BLASTX nr result
ID: Anemarrhena21_contig00023320
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Anemarrhena21_contig00023320
(787 letters)
Database: ./nr
69,698,275 sequences; 24,982,196,650 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|EMS67946.1| L-type lectin-domain containing receptor kinase I... 67 8e-11
ref|XP_004958075.1| PREDICTED: L-type lectin-domain containing r... 65 2e-10
ref|XP_007047721.1| Concanavalin A-like lectin protein kinase fa... 56 2e-10
ref|XP_003562911.1| PREDICTED: L-type lectin-domain containing r... 64 7e-10
ref|XP_008670494.1| PREDICTED: L-type lectin-domain containing r... 62 1e-09
ref|XP_006657862.1| PREDICTED: L-type lectin-domain containing r... 63 1e-09
gb|KCW76068.1| hypothetical protein EUGRSUZ_D00436 [Eucalyptus g... 50 1e-09
ref|XP_010104514.1| L-type lectin-domain containing receptor kin... 53 3e-09
gb|EAZ40356.1| hypothetical protein OsJ_24802 [Oryza sativa Japo... 61 4e-09
dbj|BAC79695.1| putative lectin-like protein kinase [Oryza sativ... 61 4e-09
ref|XP_012492069.1| PREDICTED: L-type lectin-domain containing r... 60 7e-09
ref|XP_012492068.1| PREDICTED: L-type lectin-domain containing r... 60 7e-09
ref|XP_007206505.1| hypothetical protein PRUPE_ppa019242mg [Prun... 59 9e-09
ref|XP_010090631.1| L-type lectin-domain containing receptor kin... 58 9e-09
ref|XP_012068410.1| PREDICTED: L-type lectin-domain containing r... 59 2e-08
ref|XP_010054310.1| PREDICTED: L-type lectin-domain containing r... 54 2e-08
ref|XP_007047724.1| Concanavalin A-like lectin protein kinase fa... 57 2e-08
ref|XP_007047722.1| Concanavalin A-like lectin protein kinase fa... 57 3e-08
emb|CBI35414.3| unnamed protein product [Vitis vinifera] 52 3e-08
ref|XP_010695030.1| PREDICTED: L-type lectin-domain containing r... 60 3e-08
>gb|EMS67946.1| L-type lectin-domain containing receptor kinase IX.1 [Triticum
urartu]
Length = 693
Score = 67.0 bits (162), Expect(2) = 8e-11
Identities = 33/53 (62%), Positives = 42/53 (79%), Gaps = 2/53 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDK--DVAIKSFCRVSTR 27
P+RF +NELVAAT NFA+ERKLG+GGF +Y+GLL D+ DVAIK + ST+
Sbjct: 336 PRRFRYNELVAATRNFALERKLGEGGFGAVYQGLLKDQNLDVAIKRVAKGSTQ 388
Score = 27.3 bits (59), Expect(2) = 8e-11
Identities = 12/17 (70%), Positives = 14/17 (82%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
+V GS QG+KEYISEV
Sbjct: 381 RVAKGSTQGRKEYISEV 397
>ref|XP_004958075.1| PREDICTED: L-type lectin-domain containing receptor kinase
IX.1-like [Setaria italica]
Length = 688
Score = 64.7 bits (156), Expect(2) = 2e-10
Identities = 31/55 (56%), Positives = 42/55 (76%), Gaps = 2/55 (3%)
Frame = -3
Query: 185 RRPKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDK--DVAIKSFCRVSTR 27
R P+RF +NELVAAT NFA+ERKLG+GGF +Y+G L D+ ++AIK + ST+
Sbjct: 330 RGPRRFRYNELVAATKNFALERKLGEGGFGAVYQGFLKDQNLNIAIKRVAKGSTQ 384
Score = 28.5 bits (62), Expect(2) = 2e-10
Identities = 13/17 (76%), Positives = 14/17 (82%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
+V GS QGKKEYISEV
Sbjct: 377 RVAKGSTQGKKEYISEV 393
>ref|XP_007047721.1| Concanavalin A-like lectin protein kinase family protein, putative
[Theobroma cacao] gi|508699982|gb|EOX91878.1|
Concanavalin A-like lectin protein kinase family
protein, putative [Theobroma cacao]
Length = 666
Score = 55.8 bits (133), Expect(3) = 2e-10
Identities = 25/42 (59%), Positives = 32/42 (76%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKDVAI 54
P RF F ELV+AT+NFA ERKLG+GGF +Y+ L D D+A+
Sbjct: 342 PSRFAFQELVSATNNFANERKLGEGGFGTVYRVYLADLDIAV 383
Score = 28.9 bits (63), Expect(3) = 2e-10
Identities = 11/28 (39%), Positives = 18/28 (64%)
Frame = -2
Query: 339 VTIGFAASTGLAAEIHQTLAWDFCSNLE 256
V +GF+A+TG E H +W+F S+ +
Sbjct: 280 VMVGFSAATGQNVERHTIQSWEFSSSFD 307
Score = 27.7 bits (60), Expect(3) = 2e-10
Identities = 11/17 (64%), Positives = 15/17 (88%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K+ GS+QGK+EYI+EV
Sbjct: 387 KISRGSRQGKREYITEV 403
>ref|XP_003562911.1| PREDICTED: L-type lectin-domain containing receptor kinase
IX.1-like [Brachypodium distachyon]
Length = 690
Score = 63.9 bits (154), Expect(2) = 7e-10
Identities = 31/55 (56%), Positives = 40/55 (72%), Gaps = 2/55 (3%)
Frame = -3
Query: 185 RRPKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDK--DVAIKSFCRVSTR 27
R P+RF +NELV AT NF +ERKLG+GGF +Y+G L D+ DVAIK + ST+
Sbjct: 331 RGPRRFRYNELVGATKNFVLERKLGEGGFGAVYQGFLKDQNLDVAIKRVAKGSTQ 385
Score = 27.3 bits (59), Expect(2) = 7e-10
Identities = 12/17 (70%), Positives = 14/17 (82%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
+V GS QG+KEYISEV
Sbjct: 378 RVAKGSTQGRKEYISEV 394
>ref|XP_008670494.1| PREDICTED: L-type lectin-domain containing receptor kinase
IX.1-like [Zea mays] gi|414590583|tpg|DAA41154.1| TPA:
putative lectin-domain receptor-like protein kinase
family protein [Zea mays]
Length = 696
Score = 62.0 bits (149), Expect(2) = 1e-09
Identities = 31/55 (56%), Positives = 41/55 (74%), Gaps = 2/55 (3%)
Frame = -3
Query: 185 RRPKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKD--VAIKSFCRVSTR 27
R P+RF ++ELV+AT NFA+ERKLG+GGF +YKG L D + VAIK + ST+
Sbjct: 334 RGPRRFRYDELVSATKNFALERKLGEGGFGAVYKGSLKDPNLTVAIKRVAKGSTQ 388
Score = 28.5 bits (62), Expect(2) = 1e-09
Identities = 13/17 (76%), Positives = 14/17 (82%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
+V GS QGKKEYISEV
Sbjct: 381 RVAKGSTQGKKEYISEV 397
>ref|XP_006657862.1| PREDICTED: L-type lectin-domain containing receptor kinase
IX.1-like [Oryza brachyantha]
Length = 689
Score = 63.2 bits (152), Expect(2) = 1e-09
Identities = 30/55 (54%), Positives = 42/55 (76%), Gaps = 2/55 (3%)
Frame = -3
Query: 185 RRPKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDK--DVAIKSFCRVSTR 27
R P+RF +NEL+AAT+NFA ERKLG+GGF +Y+G L D+ ++AIK + ST+
Sbjct: 333 RGPRRFRYNELIAATNNFAEERKLGEGGFGAVYQGFLKDQNIEIAIKRVAKGSTQ 387
Score = 27.3 bits (59), Expect(2) = 1e-09
Identities = 12/17 (70%), Positives = 14/17 (82%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
+V GS QG+KEYISEV
Sbjct: 380 RVAKGSTQGRKEYISEV 396
>gb|KCW76068.1| hypothetical protein EUGRSUZ_D00436 [Eucalyptus grandis]
Length = 560
Score = 50.4 bits (119), Expect(3) = 1e-09
Identities = 25/45 (55%), Positives = 32/45 (71%), Gaps = 2/45 (4%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLN--DKDVAIK 51
PK+ F +LV AT NFAIER LG+GGF +Y+G L + +VAIK
Sbjct: 241 PKKIPFKDLVVATENFAIERLLGEGGFGRVYEGYLTSVNANVAIK 285
Score = 34.7 bits (78), Expect(3) = 1e-09
Identities = 14/28 (50%), Positives = 20/28 (71%)
Frame = -2
Query: 339 VTIGFAASTGLAAEIHQTLAWDFCSNLE 256
VT GF+A+TG E+H AW+F SN++
Sbjct: 174 VTFGFSATTGTYFELHTIEAWEFSSNVQ 201
Score = 24.6 bits (52), Expect(3) = 1e-09
Identities = 11/17 (64%), Positives = 13/17 (76%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K+ GS+QG KEY SEV
Sbjct: 286 KINPGSRQGIKEYASEV 302
>ref|XP_010104514.1| L-type lectin-domain containing receptor kinase IX.1 [Morus
notabilis] gi|587913298|gb|EXC01115.1| L-type
lectin-domain containing receptor kinase IX.1 [Morus
notabilis]
Length = 568
Score = 53.1 bits (126), Expect(2) = 3e-09
Identities = 29/57 (50%), Positives = 35/57 (61%), Gaps = 2/57 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKD--VAIKSFCRVSTREEGI 15
PKRFT+ ELV T+ FA +RKLG+GG +YKG L D D VA+K S E I
Sbjct: 272 PKRFTYQELVNTTNGFAEDRKLGRGGSGHVYKGTLRDLDRQVAVKRIFGESEHSERI 328
Score = 35.8 bits (81), Expect(2) = 3e-09
Identities = 15/33 (45%), Positives = 24/33 (72%)
Frame = -2
Query: 339 VTIGFAASTGLAAEIHQTLAWDFCSNLEEGIES 241
VT+G ++STGL +E H +W+F S+L+ +ES
Sbjct: 234 VTVGISSSTGLDSEEHTISSWEFYSSLDLDVES 266
>gb|EAZ40356.1| hypothetical protein OsJ_24802 [Oryza sativa Japonica Group]
Length = 886
Score = 61.2 bits (147), Expect(2) = 4e-09
Identities = 29/53 (54%), Positives = 39/53 (73%), Gaps = 2/53 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDK--DVAIKSFCRVSTR 27
P+RF +NELV AT NFA ERKLG+GGF +Y+G L D+ ++AIK + ST+
Sbjct: 532 PRRFQYNELVVATDNFAAERKLGEGGFGAVYQGFLKDQNIEIAIKRVAKGSTQ 584
Score = 27.3 bits (59), Expect(2) = 4e-09
Identities = 12/17 (70%), Positives = 14/17 (82%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
+V GS QG+KEYISEV
Sbjct: 577 RVAKGSTQGRKEYISEV 593
>dbj|BAC79695.1| putative lectin-like protein kinase [Oryza sativa Japonica Group]
Length = 689
Score = 61.2 bits (147), Expect(2) = 4e-09
Identities = 29/53 (54%), Positives = 39/53 (73%), Gaps = 2/53 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDK--DVAIKSFCRVSTR 27
P+RF +NELV AT NFA ERKLG+GGF +Y+G L D+ ++AIK + ST+
Sbjct: 335 PRRFQYNELVVATDNFAAERKLGEGGFGAVYQGFLKDQNIEIAIKRVAKGSTQ 387
Score = 27.3 bits (59), Expect(2) = 4e-09
Identities = 12/17 (70%), Positives = 14/17 (82%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
+V GS QG+KEYISEV
Sbjct: 380 RVAKGSTQGRKEYISEV 396
>ref|XP_012492069.1| PREDICTED: L-type lectin-domain containing receptor kinase
IX.1-like [Gossypium raimondii]
gi|763776914|gb|KJB44037.1| hypothetical protein
B456_007G231500 [Gossypium raimondii]
Length = 656
Score = 60.5 bits (145), Expect(2) = 7e-09
Identities = 28/51 (54%), Positives = 38/51 (74%), Gaps = 2/51 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKD--VAIKSFCRVS 33
P+RF++N+LV AT+NF+ +RKLG+GGF +YKG ND D VA+K R S
Sbjct: 327 PRRFSYNDLVVATNNFSNQRKLGEGGFGAVYKGYFNDSDTTVAVKKISRGS 377
Score = 27.3 bits (59), Expect(2) = 7e-09
Identities = 10/17 (58%), Positives = 15/17 (88%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K+ GS+QG+KEYI+E+
Sbjct: 372 KISRGSRQGRKEYITEI 388
>ref|XP_012492068.1| PREDICTED: L-type lectin-domain containing receptor kinase
IX.1-like [Gossypium raimondii]
gi|763776912|gb|KJB44035.1| hypothetical protein
B456_007G231300 [Gossypium raimondii]
Length = 648
Score = 60.1 bits (144), Expect(2) = 7e-09
Identities = 26/42 (61%), Positives = 35/42 (83%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKDVAI 54
P+RFTF ELV+AT+NF+ ERKLG+GGF +Y+G L D D+A+
Sbjct: 324 PRRFTFEELVSATNNFSNERKLGEGGFGAVYRGYLADLDMAV 365
Score = 27.7 bits (60), Expect(2) = 7e-09
Identities = 11/17 (64%), Positives = 15/17 (88%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K+ GS+QGK+EYI+EV
Sbjct: 369 KISRGSRQGKREYITEV 385
>ref|XP_007206505.1| hypothetical protein PRUPE_ppa019242mg [Prunus persica]
gi|462402147|gb|EMJ07704.1| hypothetical protein
PRUPE_ppa019242mg [Prunus persica]
Length = 714
Score = 58.9 bits (141), Expect(2) = 9e-09
Identities = 24/42 (57%), Positives = 35/42 (83%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKDVAI 54
P+RF++++LV AT+NF+ ERKLG+GGF +YKG L D D+A+
Sbjct: 328 PRRFSYSDLVTATNNFSNERKLGEGGFGAVYKGYLTDLDIAV 369
Score = 28.5 bits (62), Expect(2) = 9e-09
Identities = 11/17 (64%), Positives = 16/17 (94%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K+ +GS+QG+KEYI+EV
Sbjct: 373 KISSGSRQGRKEYITEV 389
>ref|XP_010090631.1| L-type lectin-domain containing receptor kinase IX.1 [Morus
notabilis] gi|587950579|gb|EXC36487.1| L-type
lectin-domain containing receptor kinase IX.1 [Morus
notabilis]
Length = 652
Score = 58.2 bits (139), Expect(2) = 9e-09
Identities = 24/42 (57%), Positives = 35/42 (83%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKDVAI 54
P+RF++ +L +AT+NF+ +RKLGQGGF E+YKG LND D+ +
Sbjct: 330 PRRFSYADLASATNNFSEKRKLGQGGFGEVYKGYLNDLDLIV 371
Score = 29.3 bits (64), Expect(2) = 9e-09
Identities = 11/17 (64%), Positives = 16/17 (94%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K+ +GS+QGKKEY++EV
Sbjct: 375 KISSGSRQGKKEYVTEV 391
>ref|XP_012068410.1| PREDICTED: L-type lectin-domain containing receptor kinase
IX.1-like [Jatropha curcas] gi|643734430|gb|KDP41155.1|
hypothetical protein JCGZ_03649 [Jatropha curcas]
Length = 658
Score = 59.3 bits (142), Expect(2) = 2e-08
Identities = 27/51 (52%), Positives = 40/51 (78%), Gaps = 2/51 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKD--VAIKSFCRVS 33
P+RF++ +LV++T+NF+ ERKLG+GGF +YKG LN+ D +A+K F R S
Sbjct: 333 PRRFSYEDLVSSTNNFSDERKLGEGGFGAVYKGYLNEIDMAIAVKKFSRGS 383
Score = 27.3 bits (59), Expect(2) = 2e-08
Identities = 12/17 (70%), Positives = 14/17 (82%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K GS+QGKKEYI+EV
Sbjct: 378 KFSRGSKQGKKEYITEV 394
>ref|XP_010054310.1| PREDICTED: L-type lectin-domain containing receptor kinase
IX.1-like [Eucalyptus grandis]
Length = 593
Score = 53.5 bits (127), Expect(2) = 2e-08
Identities = 22/42 (52%), Positives = 32/42 (76%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKDVAI 54
PK+FT+ ELVA+T NFA++R LG+GGF +Y+G L +V +
Sbjct: 245 PKKFTYKELVASTGNFAVKRLLGEGGFGRVYEGYLTSMNVNV 286
Score = 33.1 bits (74), Expect(2) = 2e-08
Identities = 16/35 (45%), Positives = 20/35 (57%)
Frame = -2
Query: 339 VTIGFAASTGLAAEIHQTLAWDFCSNLEEGIESSK 235
V GF+ASTG E H AW+F SN+ + SK
Sbjct: 183 VNFGFSASTGSYVEKHTIEAWEFSSNVHVAGKKSK 217
>ref|XP_007047724.1| Concanavalin A-like lectin protein kinase family protein [Theobroma
cacao] gi|508699985|gb|EOX91881.1| Concanavalin A-like
lectin protein kinase family protein [Theobroma cacao]
Length = 659
Score = 57.4 bits (137), Expect(2) = 2e-08
Identities = 27/51 (52%), Positives = 37/51 (72%), Gaps = 2/51 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKD--VAIKSFCRVS 33
P+RF++ +LV AT+NF+ +RKLG+GGF +YKG ND D VA+K R S
Sbjct: 332 PRRFSYGDLVVATNNFSNQRKLGEGGFGAVYKGYFNDIDTAVAVKKIARGS 382
Score = 28.9 bits (63), Expect(2) = 2e-08
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K+ GS+QGKKEYI+EV
Sbjct: 377 KIARGSRQGKKEYITEV 393
>ref|XP_007047722.1| Concanavalin A-like lectin protein kinase family protein [Theobroma
cacao] gi|508699983|gb|EOX91879.1| Concanavalin A-like
lectin protein kinase family protein [Theobroma cacao]
Length = 659
Score = 57.0 bits (136), Expect(2) = 3e-08
Identities = 27/51 (52%), Positives = 38/51 (74%), Gaps = 2/51 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKD--VAIKSFCRVS 33
P+RF++ +LV AT+NF+ +RKLG+GGF +YKG L+D D VA+K R S
Sbjct: 332 PRRFSYGDLVVATNNFSNQRKLGEGGFGAVYKGYLSDIDTAVAVKKIARGS 382
Score = 28.9 bits (63), Expect(2) = 3e-08
Identities = 12/17 (70%), Positives = 15/17 (88%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K+ GS+QGKKEYI+EV
Sbjct: 377 KIARGSRQGKKEYITEV 393
>emb|CBI35414.3| unnamed protein product [Vitis vinifera]
Length = 382
Score = 51.6 bits (122), Expect(3) = 3e-08
Identities = 26/51 (50%), Positives = 36/51 (70%), Gaps = 2/51 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLNDKD--VAIKSFCRVS 33
P++F+F EL ATSNFA E+KLG+GGF +Y+G L + + VA+K R S
Sbjct: 132 PRKFSFYELALATSNFAEEQKLGEGGFGGVYRGFLRELNSYVAVKRVSRNS 182
Score = 29.3 bits (64), Expect(3) = 3e-08
Identities = 12/30 (40%), Positives = 21/30 (70%)
Frame = -2
Query: 345 KKVTIGFAASTGLAAEIHQTLAWDFCSNLE 256
+ V+IGF+A+TG ++++ +W F S LE
Sbjct: 62 ENVSIGFSAATGDLFQMNKICSWKFSSTLE 91
Score = 24.3 bits (51), Expect(3) = 3e-08
Identities = 11/17 (64%), Positives = 12/17 (70%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
+V SQQG KEY SEV
Sbjct: 177 RVSRNSQQGMKEYASEV 193
>ref|XP_010695030.1| PREDICTED: L-type lectin-domain containing receptor kinase
IX.1-like [Beta vulgaris subsp. vulgaris]
Length = 727
Score = 59.7 bits (143), Expect(2) = 3e-08
Identities = 28/51 (54%), Positives = 38/51 (74%), Gaps = 2/51 (3%)
Frame = -3
Query: 179 PKRFTFNELVAATSNFAIERKLGQGGFREIYKGLLN--DKDVAIKSFCRVS 33
PKRFT+NEL AT+NF+ ERKLG+GGF +Y+G L D+++A+K R S
Sbjct: 375 PKRFTYNELSHATNNFSEERKLGEGGFGGVYRGFLTDLDREIAVKKISRES 425
Score = 25.8 bits (55), Expect(2) = 3e-08
Identities = 11/17 (64%), Positives = 14/17 (82%)
Frame = -1
Query: 52 KVFAGSQQGKKEYISEV 2
K+ S+QGKKEY+SEV
Sbjct: 420 KISRESKQGKKEYMSEV 436