BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Anemarrhena21_contig00014882
         (3254 letters)

Database: ./nr 
           69,698,275 sequences; 24,982,196,650 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guine...  1457   0.0  
ref|XP_008779357.1| PREDICTED: DNA topoisomerase 2, partial [Pho...  1455   0.0  
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1399   0.0  
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1399   0.0  
ref|XP_009402954.1| PREDICTED: DNA topoisomerase 2-like [Musa ac...  1394   0.0  
ref|XP_009399445.1| PREDICTED: DNA topoisomerase 2-like [Musa ac...  1390   0.0  
ref|XP_010257162.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1375   0.0  
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]  1369   0.0  
emb|CDP07797.1| unnamed protein product [Coffea canephora]           1328   0.0  
ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2-like [Eucalyp...  1320   0.0  
ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cac...  1318   0.0  
ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cac...  1317   0.0  
gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984...  1303   0.0  
ref|XP_009630917.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1300   0.0  
ref|XP_009800897.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1298   0.0  
ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum...  1296   0.0  
ref|XP_010324649.1| PREDICTED: DNA topoisomerase 2 isoform X1 [S...  1281   0.0  
ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2 isoform X2 [S...  1279   0.0  
ref|XP_008231457.1| PREDICTED: DNA topoisomerase 2 isoform X1 [P...  1274   0.0  
ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [P...  1272   0.0  

>ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guineensis]
          Length = 1486

 Score = 1457 bits (3773), Expect = 0.0
 Identities = 766/1070 (71%), Positives = 855/1070 (79%), Gaps = 10/1070 (0%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSG+V +LLSWADFKQ+KELKKTDGTK+Q+I GIPKL+DANDAGGRNSEKCTLILTEGDS
Sbjct: 406  KSGVVNSLLSWADFKQSKELKKTDGTKRQRIVGIPKLEDANDAGGRNSEKCTLILTEGDS 465

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGR+HYGVFPLRGKLLNVREA+ +QI +NAEIQ+IKQILGLQ GKEY+S
Sbjct: 466  AKALAMAGISVVGRNHYGVFPLRGKLLNVREASHKQIMDNAEIQSIKQILGLQQGKEYES 525

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
             KGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKI  FMVEFITPIVKA+H   K
Sbjct: 526  TKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFMVEFITPIVKATHNRNK 585

Query: 2709 -VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANE 2533
             VL FY+MPEYEAWKESL GNASGWSIKYYKGLGTST+KEGKEYF+ I +HKK F+W + 
Sbjct: 586  NVLPFYSMPEYEAWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFQDIVKHKKDFMWVDN 645

Query: 2532 QDGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSI 2353
            QDGDAIELAFSKKKIEARKNWLRQFE GTYLD +EK IKYSDFVNKELILFS ADLQRSI
Sbjct: 646  QDGDAIELAFSKKKIEARKNWLRQFEPGTYLDQREKLIKYSDFVNKELILFSMADLQRSI 705

Query: 2352 PSVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDF 2173
            PS+VDGLKPGQRKILFC+FKRNFVKEAKVAQF+GYVSEHSAYHHGEQSL STI+GMAQDF
Sbjct: 706  PSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFAGYVSEHSAYHHGEQSLASTIIGMAQDF 765

Query: 2172 VGSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQS 1993
            VGSNNINL QPNGQFGTR++GGKD ASARYIYT LSP+TRFLFPK        LNEDGQ 
Sbjct: 766  VGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPLTRFLFPKDDDILLDYLNEDGQL 825

Query: 1992 IEPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGF 1813
            IEP WY+PIIPMVLVNGSEGIGTGWS+++PNYNPRD++ANVRRLLN+EPMQPMDPWYR F
Sbjct: 826  IEPTWYMPIIPMVLVNGSEGIGTGWSTFVPNYNPRDIVANVRRLLNNEPMQPMDPWYRSF 885

Query: 1812 KGTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKE 1633
            KG IEKSA KE GVTYTI+G+ EEVDSTTL+ITELPIR WT DY +FL+ +M G DKIKE
Sbjct: 886  KGLIEKSASKEAGVTYTITGLAEEVDSTTLKITELPIRRWTQDYKEFLESLMTGNDKIKE 945

Query: 1632 PFIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKK 1453
            PFI+D R  NDD  VHFE+IL+EE L  A +EGLEKKFKL TTIST+NMHLFDS GVIKK
Sbjct: 946  PFIKDYREQNDDVNVHFEIILTEEKLNMAREEGLEKKFKLTTTISTTNMHLFDSKGVIKK 1005

Query: 1452 YDSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRA 1273
            YD+PEQILEDFFHLRL+FY KRKK               KVRFIL VV GEIIVNNRKRA
Sbjct: 1006 YDTPEQILEDFFHLRLEFYAKRKKALLDNLELDLLKLDNKVRFILGVVRGEIIVNNRKRA 1065

Query: 1272 ELFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSI 1093
            +LF EL QKGF PFPKK+KGIDAAIAGATV           +  GG +A+DYEYLLSM+I
Sbjct: 1066 DLFLELQQKGFAPFPKKSKGIDAAIAGATVEEDGNEESPEVVNGGGARAADYEYLLSMAI 1125

Query: 1092 GTLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQ 913
            GTLT EKVQELCAE+ + E E+EEL+ +SP+ LWM+DLDA E +LDEQ+RKD E + +K+
Sbjct: 1126 GTLTWEKVQELCAERKKLEDEVEELRKSSPRDLWMKDLDAFEMELDEQERKDAE-EGIKR 1184

Query: 912  ELRRKINTGAAVSRKAGPKKPRKNNATKGSXXXXXXXXXXXXGNVLEMGKPKPRGGQKKA 733
            E R K  TGAA+S K GPKKPRKNNA   S            GN  E  KPKPRG  KKA
Sbjct: 1185 ETRMKNITGAALS-KQGPKKPRKNNANNSS--TVSDVTSTDAGNAPEASKPKPRGRAKKA 1241

Query: 732  -AAKTSVVES--DDEDELIELKDRLAAYNLDSSPD-QASVETEE-LPQEVVTKKQPGKRA 568
             A K +VVES  DDE+E++ LKDRLAAYNLDSSPD Q+++ETE  L Q+   KK+P KR 
Sbjct: 1242 PAKKVAVVESDEDDEEEVLALKDRLAAYNLDSSPDHQSAMETEAVLSQKEQRKKEPSKRT 1301

Query: 567  AARNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRKPRNATAK- 391
            AAR   ST   +         + M TI+ED  DEDF+++EAP       G+KP N  AK 
Sbjct: 1302 AARKAPST--FTEISDGDDAEDDMPTILEDDDDEDFELVEAPPKGGKARGKKPANEKAKG 1359

Query: 390  -DTTTANPRKRGGTQGKTVLSQKLITDVLKSVKNA--SPEKKVRKMRASPFNKKSGSVLG 220
                T   RKRG  Q K VLSQKLIT+VLK V+N   SPEKKVRKMRASPFNKKSGSVLG
Sbjct: 1360 GKAGTTTTRKRGTAQSKPVLSQKLITEVLKPVENTGISPEKKVRKMRASPFNKKSGSVLG 1419

Query: 219  RAGGSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRTKVTYVESGS 70
            R G S   SE+S GS S GN  AE+N V      PKREN  +  Y+ES S
Sbjct: 1420 RIGSSPTSSEES-GSSSPGN-PAELNEVLAAAARPKRENSRRAVYIESDS 1467


>ref|XP_008779357.1| PREDICTED: DNA topoisomerase 2, partial [Phoenix dactylifera]
          Length = 1401

 Score = 1455 bits (3766), Expect = 0.0
 Identities = 768/1067 (71%), Positives = 856/1067 (80%), Gaps = 7/1067 (0%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSG+V +LLSWADFKQ+KELKKTDGTK+Q+ITGIPKL+DANDAGGRNSEKCTLILTEGDS
Sbjct: 327  KSGVVNSLLSWADFKQSKELKKTDGTKRQRITGIPKLEDANDAGGRNSEKCTLILTEGDS 386

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGR++YGVFPLRGKLLNVREA+ +QI  NAEIQNIKQILGLQHGKEYDS
Sbjct: 387  AKALAMAGISVVGRNYYGVFPLRGKLLNVREASHKQIMENAEIQNIKQILGLQHGKEYDS 446

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
             KGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKI  FMVEFITPIVKA+H   K
Sbjct: 447  TKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFMVEFITPIVKATHSKNK 506

Query: 2709 -VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANE 2533
             VL FY+MPEYEAWKE L GNASGWSIKYYKGLGTST+KEGKEYF  ID+HKK FIW ++
Sbjct: 507  TVLPFYSMPEYEAWKERLGGNASGWSIKYYKGLGTSTSKEGKEYFHDIDKHKKDFIWVDD 566

Query: 2532 QDGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSI 2353
            QDGDAIELAFSKKKIEARKNWLR FE GTYLD ++K IKYSDFVNKELILFS ADLQRSI
Sbjct: 567  QDGDAIELAFSKKKIEARKNWLRHFETGTYLDQRQKHIKYSDFVNKELILFSMADLQRSI 626

Query: 2352 PSVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDF 2173
            PS VDGLKPGQRKILFC+FKRNFVKEAKVAQFSGYVSEHSAYHHGEQSL STI+GMAQDF
Sbjct: 627  PSTVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDF 686

Query: 2172 VGSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQS 1993
            VGSNNINL QPNGQFGTR++GGKD ASARYIYT LSP+TRFLFPK        LNEDGQS
Sbjct: 687  VGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPLTRFLFPKDDDMLLDYLNEDGQS 746

Query: 1992 IEPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGF 1813
            IEP WY+PIIP+VLVNGSEGIGTGWSS++PNYNPRD++ANVRRLLN EPMQPMDPWYRGF
Sbjct: 747  IEPTWYMPIIPLVLVNGSEGIGTGWSSFVPNYNPRDIVANVRRLLNDEPMQPMDPWYRGF 806

Query: 1812 KGTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKE 1633
            KG IEKSA KE GVTYTI+G+IEEVDSTTLRITELPIR WT DY +FL+ MM G DKIKE
Sbjct: 807  KGLIEKSATKEAGVTYTITGLIEEVDSTTLRITELPIRRWTQDYKEFLESMMTGNDKIKE 866

Query: 1632 PFIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKK 1453
            PFI+D R +NDD  VHFE+IL+EE LK A +EGLE+KFKL TTIST+NMHLFDS GVIKK
Sbjct: 867  PFIKDYREHNDDINVHFEIILTEEKLKMAKEEGLERKFKLTTTISTTNMHLFDSEGVIKK 926

Query: 1452 YDSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRA 1273
            YD+PEQILEDFFHLRL++Y KRKKV              KVRFIL VV GEIIV+NRKRA
Sbjct: 927  YDTPEQILEDFFHLRLEYYAKRKKVLLDNLEMDLLKLDNKVRFILGVVRGEIIVSNRKRA 986

Query: 1272 ELFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSI 1093
            +LF EL QKGFTPFPKK+KGIDAAIAGAT           E  +   +A+DYEYLLSM+I
Sbjct: 987  DLFLELQQKGFTPFPKKSKGIDAAIAGAT-----EEDDNEESPEVAARATDYEYLLSMAI 1041

Query: 1092 GTLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQ 913
            GTLT EKVQELCA++ + E E+EELK +SP+ LWM+DLD  E++LDE +RKD E + +K+
Sbjct: 1042 GTLTWEKVQELCADRKKLEGEVEELKKSSPRDLWMKDLDDFERELDELERKDAE-EGMKR 1100

Query: 912  ELRRKINTGAAVSRKAGPKKPRKNNATKGSXXXXXXXXXXXXGNVLEMGKPKPRGGQKKA 733
            E R K  TGAAVSR+ GPKKPRKNNA   S            GN  E  K K RGG KKA
Sbjct: 1101 ETRTKNITGAAVSRQ-GPKKPRKNNANNSS--SISNVTSTDAGNAPEPSKLKARGGAKKA 1157

Query: 732  -AAKTSVVESDDEDELIELKDRLAAYNLDSSPDQASVETE-ELPQEVVTKKQPGKRAAAR 559
             A K  VVESD+++E++ LKDRLAAYNLDSSPDQ+++E E  L Q    KK+P KR A R
Sbjct: 1158 PAKKVMVVESDEDEEVLALKDRLAAYNLDSSPDQSAMEAEAALSQREHRKKEPSKRTALR 1217

Query: 558  NTKSTL-RISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRKPRNATAK-DT 385
               ST   IS         E    I+ +  DEDF++ EAPKG +   GRKP N  AK   
Sbjct: 1218 KAPSTFTEISDGDDV----EDNMPIVGEDDDEDFELAEAPKGGQ-ARGRKPANEKAKRGK 1272

Query: 384  TTANPRKRGGTQGKTVLSQKLITDVLKSVKNA--SPEKKVRKMRASPFNKKSGSVLGRAG 211
             T   RKRG  Q K VLSQKLIT+VLK V+NA  SP+KKVRKMRASPFNKKSG VLGR G
Sbjct: 1273 ATTTTRKRGAAQSKPVLSQKLITEVLKPVENAGISPDKKVRKMRASPFNKKSGPVLGRTG 1332

Query: 210  GSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRTKVTYVESGS 70
             S  +SE+S GS SSG+  AEMN V +    PKR NR +  Y+ES S
Sbjct: 1333 SSPTDSEES-GSHSSGS-PAEMNEVPVAAPRPKRGNRIRAVYMESDS 1377


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score = 1399 bits (3621), Expect = 0.0
 Identities = 738/1087 (67%), Positives = 849/1087 (78%), Gaps = 29/1087 (2%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSG+VENLLSWADFKQ+K+LKKTDG K+Q+ITGI KL+DANDAGGRNSEKCTLILTEGDS
Sbjct: 404  KSGVVENLLSWADFKQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDS 463

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGR++YGVFPLRGKLLNVREAT +QI +NAEIQNIKQILGLQHGKEYDS
Sbjct: 464  AKALAMAGISVVGRNNYGVFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDS 523

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            VK LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKI  F+VEFITPIVKA+HK+GK
Sbjct: 524  VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGK 583

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
            VLSFY+MPEYE+WK  L GNASGWSIKYYKGLGTST+KEGKEYF+ + +HKK F+W +++
Sbjct: 584  VLSFYSMPEYESWKX-LGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDR 642

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DGDAIELAFSKKKIEARKNWLRQFE GT LD KEK IKYSDFVNKELILFS ADLQRSIP
Sbjct: 643  DGDAIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIP 702

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S+VDGLKPGQRKILFCAFKRN +KEAKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+V
Sbjct: 703  SMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYV 762

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINLFQPNGQFGTR++GGKD ASARYIYT LSPITRFLFPK        LNEDGQSI
Sbjct: 763  GSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSI 822

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WY+PIIP VLVNGSEGIGTGWSSYIPNYNPRD++AN++RLLN EPM+PMDPWY+GFK
Sbjct: 823  EPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFK 882

Query: 1809 GTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEP 1630
            G IEK+A KE G +YT+SGIIEE++ TTLRITELPIR WT DY +FL+ +M G DKIKEP
Sbjct: 883  GLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEP 942

Query: 1629 FIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKY 1450
            FI+D + +NDDT VHFE+ILSEENL  A QEGL KKFKL TTISTSNMHLFD  G IKKY
Sbjct: 943  FIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKY 1002

Query: 1449 DSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAE 1270
            D+PEQILE+FFHLRL+FYEKRKK               KVRFIL VV GEIIV+NRKR +
Sbjct: 1003 DNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVD 1062

Query: 1269 LFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIG 1090
            LF EL QKGFTPFPKKTK ++AA+AGA             +   GV+ASDYEYLLSM+IG
Sbjct: 1063 LFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIG 1122

Query: 1089 TLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQE 910
            TLT+EKVQELC+++D+  HE+EEL+  +P +LWM DLDALEK+LDEQD+ D +A+  ++E
Sbjct: 1123 TLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALEKELDEQDKNDAQAEEARKE 1182

Query: 909  LRRKI--NTGAAVSRKAGPKKPRKNNATKGS------XXXXXXXXXXXXGNVLEMGKPKP 754
            L+ ++    G   SR+A PK PRK NA K S                    V E+ KPK 
Sbjct: 1183 LKNRVMSEAGMKASRQA-PKNPRKTNAKKPSTSETVTESVAASSVGSAMETVPEVVKPKG 1241

Query: 753  RGGQ-KKAAAKTS---VVESDDED-ELIELKDRLAAYNLDSSPDQASVETEELPQEVVTK 589
            RGG+ KKA AK     +V+SD++D ++IELK+RLAAYNLDSSP+Q++V   E+ +    K
Sbjct: 1242 RGGRPKKAPAKKDNMRLVDSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAKK 1301

Query: 588  KQPGKRAAARNTKSTLRISXXXXXXXDGERMQTIIEDG-----SDEDF--QVMEAPKGKK 430
            K+P KRAAA+   S+           DG  +QTI E+      SDEDF  +V EAPKG +
Sbjct: 1302 KEPSKRAAAQKQPSSY---TEISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGGR 1358

Query: 429  TGAGRKPRNATAKDTTTANPRKRGGTQGKT-VLSQKLITDVLKSVKNA--SPEKKVRKMR 259
               GRKP    A     A+ +KRG    +T VL QK ITD+LK  +NA  SPEKKVRKMR
Sbjct: 1359 --GGRKP---AANGKAAASTKKRGAANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKMR 1413

Query: 258  ASPFNKKSGSVLGRAGGSAIE------SEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRT 97
            ASPFNKKSGSVLGR GG   +       E   G+ S+    AE++ V   R  P+R NR 
Sbjct: 1414 ASPFNKKSGSVLGRVGGMVGDISPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNRG 1473

Query: 96   KVTYVES 76
            K  YV S
Sbjct: 1474 KAKYVIS 1480


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score = 1399 bits (3620), Expect = 0.0
 Identities = 738/1088 (67%), Positives = 849/1088 (78%), Gaps = 30/1088 (2%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSG+VENLLSWADFKQ+K+LKKTDG K+Q+ITGI KL+DANDAGGRNSEKCTLILTEGDS
Sbjct: 404  KSGVVENLLSWADFKQSKDLKKTDGAKRQRITGITKLEDANDAGGRNSEKCTLILTEGDS 463

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGR++YGVFPLRGKLLNVREAT +QI +NAEIQNIKQILGLQHGKEYDS
Sbjct: 464  AKALAMAGISVVGRNNYGVFPLRGKLLNVREATHKQIMDNAEIQNIKQILGLQHGKEYDS 523

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            VK LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKI  F+VEFITPIVKA+HK+GK
Sbjct: 524  VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGK 583

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
            VLSFY+MPEYE+WK  L GNASGWSIKYYKGLGTST+KEGKEYF+ + +HKK F+W +++
Sbjct: 584  VLSFYSMPEYESWKX-LGGNASGWSIKYYKGLGTSTSKEGKEYFKDLHKHKKDFLWVDDR 642

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DGDAIELAFSKKKIEARKNWLRQFE GT LD KEK IKYSDFVNKELILFS ADLQRSIP
Sbjct: 643  DGDAIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLIKYSDFVNKELILFSMADLQRSIP 702

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S+VDGLKPGQRKILFCAFKRN +KEAKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+V
Sbjct: 703  SMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYV 762

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINLFQPNGQFGTR++GGKD ASARYIYT LSPITRFLFPK        LNEDGQSI
Sbjct: 763  GSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKGDDILLDYLNEDGQSI 822

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WY+PIIP VLVNGSEGIGTGWSSYIPNYNPRD++AN++RLLN EPM+PMDPWY+GFK
Sbjct: 823  EPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPWYKGFK 882

Query: 1809 GTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEP 1630
            G IEK+A KE G +YT+SGIIEE++ TTLRITELPIR WT DY +FL+ +M G DKIKEP
Sbjct: 883  GLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGNDKIKEP 942

Query: 1629 FIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKY 1450
            FI+D + +NDDT VHFE+ILSEENL  A QEGL KKFKL TTISTSNMHLFD  G IKKY
Sbjct: 943  FIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKGTIKKY 1002

Query: 1449 DSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAE 1270
            D+PEQILE+FFHLRL+FYEKRKK               KVRFIL VV GEIIV+NRKR +
Sbjct: 1003 DNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRVD 1062

Query: 1269 LFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIG 1090
            LF EL QKGFTPFPKKTK ++AA+AGA             +   GV+ASDYEYLLSM+IG
Sbjct: 1063 LFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLLSMAIG 1122

Query: 1089 TLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQE 910
            TLT+EKVQELC+++D+  HE+EEL+  +P +LWM DLDALEK+LDEQD+ D +A+  ++E
Sbjct: 1123 TLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALEKELDEQDKNDAQAEEARKE 1182

Query: 909  LRRKI--NTGAAVSRKAGPKKPRKNNATKGS------XXXXXXXXXXXXGNVLEMGKPKP 754
            L+ ++    G   SR+A PK PRK NA K S                    V E+ KPK 
Sbjct: 1183 LKNRVMSEAGMKASRQA-PKNPRKTNAKKPSTSETVTESVAASSVGSAMETVPEVVKPKG 1241

Query: 753  RGGQ-KKAAAKTS----VVESDDED-ELIELKDRLAAYNLDSSPDQASVETEELPQEVVT 592
            RGG+ KKA AK      +V+SD++D ++IELK+RLAAYNLDSSP+Q++V   E+ +    
Sbjct: 1242 RGGRPKKAPAKKQDNMRLVDSDEDDVDVIELKERLAAYNLDSSPEQSAVMETEVAKVPAK 1301

Query: 591  KKQPGKRAAARNTKSTLRISXXXXXXXDGERMQTIIEDG-----SDEDF--QVMEAPKGK 433
            KK+P KRAAA+   S+           DG  +QTI E+      SDEDF  +V EAPKG 
Sbjct: 1302 KKEPSKRAAAQKQPSSY---TEISDDDDGMDVQTIREESIGEIVSDEDFEPEVEEAPKGG 1358

Query: 432  KTGAGRKPRNATAKDTTTANPRKRGGTQGKT-VLSQKLITDVLKSVKNA--SPEKKVRKM 262
            +   GRKP    A     A+ +KRG    +T VL QK ITD+LK  +NA  SPEKKVRKM
Sbjct: 1359 R--GGRKP---AANGKAAASTKKRGAANKQTSVLGQKKITDLLKPAENAGVSPEKKVRKM 1413

Query: 261  RASPFNKKSGSVLGRAGGSAIE------SEDSAGSLSSGNLEAEMNGVRLTRNMPKRENR 100
            RASPFNKKSGSVLGR GG   +       E   G+ S+    AE++ V   R  P+R NR
Sbjct: 1414 RASPFNKKSGSVLGRVGGMVGDISPMGSEEQQTGTSSASTDSAELSEVVPARPRPQRVNR 1473

Query: 99   TKVTYVES 76
             K  YV S
Sbjct: 1474 GKAKYVIS 1481


>ref|XP_009402954.1| PREDICTED: DNA topoisomerase 2-like [Musa acuminata subsp.
            malaccensis]
          Length = 1473

 Score = 1394 bits (3609), Expect = 0.0
 Identities = 724/1069 (67%), Positives = 836/1069 (78%), Gaps = 9/1069 (0%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSG+V  LL+WADFKQ+KELKKTDG K+Q+ITGIPKL+DANDAGGRNS+KCTL+LTEGDS
Sbjct: 410  KSGVVNTLLTWADFKQSKELKKTDGAKRQRITGIPKLEDANDAGGRNSDKCTLVLTEGDS 469

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGR++YGVFPLRGKLLNVREA  +QI +NAEIQN+KQILGLQHGKEYDS
Sbjct: 470  AKALAMAGISVVGRNYYGVFPLRGKLLNVREANHKQIMDNAEIQNVKQILGLQHGKEYDS 529

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
             KGLRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+  FMVEFITP++KA++   K
Sbjct: 530  TKGLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFMVEFITPLLKATNNKNK 589

Query: 2709 -VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANE 2533
             VLSFY+MPEYEAWKESL GN+SGWSIKYYKGLGTS ++EGKEYF+ ID+HKK F+WA+E
Sbjct: 590  TVLSFYSMPEYEAWKESLGGNSSGWSIKYYKGLGTSKSEEGKEYFKDIDKHKKEFVWADE 649

Query: 2532 QDGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSI 2353
            QDG+AIELAFSKKKIEARKNWLRQFE   YLD K+K IKYSDF+NKELILFSRADLQRSI
Sbjct: 650  QDGNAIELAFSKKKIEARKNWLRQFEPDNYLDQKQKLIKYSDFINKELILFSRADLQRSI 709

Query: 2352 PSVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDF 2173
            PS+VDGLKPGQRKILFCAFKRNFVK+AKVAQF GYVSE SAYHHGEQSL +TI+GMAQDF
Sbjct: 710  PSMVDGLKPGQRKILFCAFKRNFVKQAKVAQFVGYVSEKSAYHHGEQSLSTTIIGMAQDF 769

Query: 2172 VGSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQS 1993
            VGSNNINL  P GQFGTR++GGKD ASARYI+TC+SP+TRFLF K        LNEDGQS
Sbjct: 770  VGSNNINLLLPEGQFGTRHQGGKDHASARYIFTCMSPVTRFLFSKDDDILLDYLNEDGQS 829

Query: 1992 IEPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGF 1813
            IEP WY+P+IP VLVNGSEGIGTGWSSY+PNYNP+D++AN+RRLLN EPMQPMDPWYRGF
Sbjct: 830  IEPTWYMPVIPTVLVNGSEGIGTGWSSYVPNYNPKDIVANIRRLLNDEPMQPMDPWYRGF 889

Query: 1812 KGTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKE 1633
            KG IEKSA KE GVTYTI+G+IEEVD+TTLRITELP+R WT DY +FL+ MM G DKIKE
Sbjct: 890  KGRIEKSATKEAGVTYTIAGVIEEVDNTTLRITELPVRRWTQDYKEFLESMMTGNDKIKE 949

Query: 1632 PFIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKK 1453
            PFI+D R YNDD  VHFEV L+EEN+  A QEGLEKKFKL TTI T+NMHLFDS GVIKK
Sbjct: 950  PFIKDYREYNDDKTVHFEVTLTEENMNIARQEGLEKKFKLTTTIGTTNMHLFDSKGVIKK 1009

Query: 1452 YDSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRA 1273
            YD+PEQILE+FFH+R +FYEKRKK               K RFIL VV GEIIV+NRKRA
Sbjct: 1010 YDNPEQILEEFFHMRYEFYEKRKKALLDNLELDLLKLDNKARFILGVVRGEIIVSNRKRA 1069

Query: 1272 ELFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSI 1093
            +LF EL QKGFTP PKK KGIDA +AGA            E+ KGGVKASDYEYL+ M I
Sbjct: 1070 DLFLELQQKGFTPMPKKKKGIDAVVAGAVEEEEDQEEESPEVGKGGVKASDYEYLMCMPI 1129

Query: 1092 GTLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQ 913
            G+LT+EKVQELCA+KDR E E++EL+ TS K+LW+++LDALE++LD+ +RKD E + V++
Sbjct: 1130 GSLTLEKVQELCADKDRLEGEVDELRRTSAKSLWLKELDALEEELDKLERKDAEDEGVRK 1189

Query: 912  ELRRKINTGAAVSRKAGPKKPRKNNATKGSXXXXXXXXXXXXGNVLEMGKPKPRGGQKKA 733
            E+R K   G A SR  GPKKPRKN A   S                + G+ KPRG  K+A
Sbjct: 1190 EMRMKTTAGLAPSR-PGPKKPRKNAANNSS-------VVGSEATATDAGQKKPRGATKRA 1241

Query: 732  AAKTSVV--ESDDEDELIELKDRLAAYNLDSSPDQ--ASVETEELPQEVVTKKQPGKRAA 565
             AK  VV    D++D+++ LKDRLAAYNLDSSPD   A   T+ +  +   KKQ  + +A
Sbjct: 1242 PAKQRVVVESGDEDDDILALKDRLAAYNLDSSPDHHPAMETTDAVVGQGEDKKQADRNSA 1301

Query: 564  ARNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRKPRNATAKDT 385
            A    +++ +S        G  M  I ED +DEDF V+EAPKG K G G+KP  A  K T
Sbjct: 1302 ATRKATSIDLS-DDEDNEAGNHMPAIDED-NDEDFSVVEAPKGGK-GRGKKP--AKEKAT 1356

Query: 384  TTANPRKRGGTQGKTVLSQKLITDVLKSVKNA----SPEKKVRKMRASPFNKKSGSVLGR 217
            TTA  RKRG      V SQK IT+VLK  +NA    SP+KKVRKMRASPFN KSGSVLGR
Sbjct: 1357 TTAT-RKRG--LALPVSSQKRITEVLKPAENATTRISPQKKVRKMRASPFNNKSGSVLGR 1413

Query: 216  AGGSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRTKVTYVESGS 70
              GS   SEDS GS + G   + +N V   R  P+R N T+  YV S S
Sbjct: 1414 LKGSPSGSEDSGGSSNGG--PSPINEVAAARTRPRRANSTRAVYVLSDS 1460


>ref|XP_009399445.1| PREDICTED: DNA topoisomerase 2-like [Musa acuminata subsp.
            malaccensis]
          Length = 1466

 Score = 1390 bits (3599), Expect = 0.0
 Identities = 735/1067 (68%), Positives = 834/1067 (78%), Gaps = 7/1067 (0%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSG+V  LL+WADFKQ+KELKKTDG K+Q+ITGIPKL+DANDAGG+NS+KCTLILTEGDS
Sbjct: 404  KSGVVNTLLTWADFKQSKELKKTDGAKRQRITGIPKLEDANDAGGKNSDKCTLILTEGDS 463

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGR++YGVFPLRGKLLNVREA  +QI +NAEIQNIKQILGLQHGKEYDS
Sbjct: 464  AKALAMAGISVVGRNYYGVFPLRGKLLNVREANHKQILDNAEIQNIKQILGLQHGKEYDS 523

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
             KGLRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+  FMVEFITP++KA++   K
Sbjct: 524  AKGLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFMVEFITPLLKATNNKNK 583

Query: 2709 -VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANE 2533
             VLSFY+MPEYEAWKESL GNA+GWSIKYYKGLGTS ++EGK+YF+AID+HKK F+W +E
Sbjct: 584  TVLSFYSMPEYEAWKESLGGNANGWSIKYYKGLGTSKSEEGKDYFKAIDKHKKDFVWVDE 643

Query: 2532 QDGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSI 2353
            QDGDAIELAFSKKKIEARKNWLRQFE   YLD +EK IKYSDF+NKELILFSRADLQRSI
Sbjct: 644  QDGDAIELAFSKKKIEARKNWLRQFEPENYLDQREKLIKYSDFINKELILFSRADLQRSI 703

Query: 2352 PSVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDF 2173
            PS+VDGLKPGQRKILFCAFKRNFVK+AKVAQF GYVSE SAYHHGEQSL +TI+GMAQDF
Sbjct: 704  PSMVDGLKPGQRKILFCAFKRNFVKQAKVAQFVGYVSEKSAYHHGEQSLATTIIGMAQDF 763

Query: 2172 VGSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQS 1993
            VGSNNINL QP GQFGTR++GGKD ASARYI+TCLSPITRFLFPK        LNEDGQS
Sbjct: 764  VGSNNINLLQPEGQFGTRHQGGKDHASARYIFTCLSPITRFLFPKDDDILLDYLNEDGQS 823

Query: 1992 IEPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGF 1813
            IEP WY+PIIPMVL NGSEGIGTGWSSYIPNYNP+D++ANVRRLLN+EPMQPMDPWYRGF
Sbjct: 824  IEPTWYMPIIPMVLANGSEGIGTGWSSYIPNYNPKDIVANVRRLLNNEPMQPMDPWYRGF 883

Query: 1812 KGTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKE 1633
             G IEKSA KE GVTYTI+G IEEV+ TTLRITELPIR WT DY +FL+ MM G DK KE
Sbjct: 884  TGRIEKSATKEAGVTYTITGAIEEVNGTTLRITELPIRRWTQDYKEFLESMMTGNDKSKE 943

Query: 1632 PFIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKK 1453
            PFI+D R YNDD  VHFEV L+E+NL  A QEGLEKKFKL T+I T+NMHLFD  GVIKK
Sbjct: 944  PFIKDYREYNDDKTVHFEVTLTEDNLSIARQEGLEKKFKLTTSIGTTNMHLFDPKGVIKK 1003

Query: 1452 YDSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRA 1273
            YD+ EQILE+FFHLR +FYEKRKK               KVRFIL VV GEIIVNNRKRA
Sbjct: 1004 YDNSEQILEEFFHLRYEFYEKRKKALLDNLEFQLLKLDNKVRFILGVVRGEIIVNNRKRA 1063

Query: 1272 ELFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSI 1093
            +LF EL QKGF P PKKTKGIDAA A              E  K GVKASDYEYL+SM I
Sbjct: 1064 DLFLELQQKGFAPMPKKTKGIDAA-ATEEEEEDEQEEESPEAGKRGVKASDYEYLMSMPI 1122

Query: 1092 GTLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQ 913
            GTLT+EKVQELCAEKD+ E E++EL+ TSP++LW+++LDALE++LD+ +RKD EA    +
Sbjct: 1123 GTLTLEKVQELCAEKDKLEGEVDELRRTSPRSLWLKELDALEEELDKLERKDAEA----E 1178

Query: 912  ELRRKINTGAAVSRKAGPKKPRKNNATKGSXXXXXXXXXXXXGNVLEMGKPKPRGGQKKA 733
            E+R K N GA  SR+A PKKPRK  + K                V + G+ K  GG K+A
Sbjct: 1179 EIRMKNNAGAVPSRQA-PKKPRKKASNKS--------VTGPEKTVTDAGQKKTNGGSKRA 1229

Query: 732  -AAKTSVVESDDEDELIELKDRLAAYNLDSSPDQASVETEE--LPQEVVTKKQPGKRAAA 562
               K +V+ESD++D++ +LKDRLAAYNLDSSPDQ  +ET+   + Q+   KKQ  + AAA
Sbjct: 1230 PVKKNTVIESDEDDDIDDLKDRLAAYNLDSSPDQTVMETDSVVVEQQGGQKKQASRTAAA 1289

Query: 561  RNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRKPRNATAKDTT 382
            R  K+T  +            M TI ED  D+DF ++E PKG+K   GRKP N  AK  T
Sbjct: 1290 R--KATHTVLSDNEDDEAQNYMPTIEED-KDKDFNLVE-PKGRKV-RGRKPANEKAKPAT 1344

Query: 381  TANPRKRGGTQ-GKTVLSQKLITDVLKSVKNA--SPEKKVRKMRASPFNKKSGSVLGRAG 211
            T   RKRG  Q  K VLSQKLIT+VLK  +N   SPEKK+RKMR SPFNK+SGSVLGR  
Sbjct: 1345 TT--RKRGPAQSSKPVLSQKLITEVLKPAENGGNSPEKKMRKMRDSPFNKRSGSVLGRPT 1402

Query: 210  GSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRTKVTYVESGS 70
             S   SEDS G   SG  E   N V   R  PKREN TK  YV S S
Sbjct: 1403 SSPSGSEDSNGLSPSGPAET-TNVVAAARTRPKRENMTKAVYVLSDS 1448


>ref|XP_010257162.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Nelumbo
            nucifera]
          Length = 1489

 Score = 1375 bits (3559), Expect = 0.0
 Identities = 735/1092 (67%), Positives = 841/1092 (77%), Gaps = 32/1092 (2%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSG+VENLLSWADFKQ+K+LKKTDG K+Q+ITGI KL+DANDAGG+NSEKCTLILTEGDS
Sbjct: 404  KSGVVENLLSWADFKQSKDLKKTDGAKRQRITGITKLEDANDAGGKNSEKCTLILTEGDS 463

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGR+HYGVFPLRGKLLNVREA  +QI  NAEIQNIKQILGLQHGKEYDS
Sbjct: 464  AKALAMAGISVVGRNHYGVFPLRGKLLNVREANHKQIMENAEIQNIKQILGLQHGKEYDS 523

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            VK LRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLKI  F+VEFITP+VKA HK+G+
Sbjct: 524  VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKIPSFLVEFITPVVKAIHKNGR 583

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
            VLSFY+MPEYE+WKESL+GNASGWSIKYYKGLGTST+KEGKEYF+ +D HKK FIW NEQ
Sbjct: 584  VLSFYSMPEYESWKESLAGNASGWSIKYYKGLGTSTSKEGKEYFKDLDMHKKDFIWINEQ 643

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DGDAIELAFSKKKIEARKNWLR FE GTYLD KEK IKYSDFVNKELILFS ADLQRSIP
Sbjct: 644  DGDAIELAFSKKKIEARKNWLRNFEPGTYLDQKEKFIKYSDFVNKELILFSMADLQRSIP 703

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S+VDGLKPGQRKILFCAFKRNF+KEAKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+V
Sbjct: 704  SMVDGLKPGQRKILFCAFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLMSTIIGMAQDYV 763

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINLFQPNGQFGTR++GGKD ASARYIYT LSPITRFLFPK        LNEDGQSI
Sbjct: 764  GSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSI 823

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WY+PI+PMVLVNGSEGIGTGWSSYIPNYNPRD++AN+RRLLN EPM+ MDPWY+GF+
Sbjct: 824  EPTWYMPIVPMVLVNGSEGIGTGWSSYIPNYNPRDIVANIRRLLNGEPMEAMDPWYKGFR 883

Query: 1809 GTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEP 1630
            G IEK+A KE G +YT+SGIIE+ D                   +FL+ +M G DKIKEP
Sbjct: 884  GLIEKTATKEAGSSYTVSGIIEDXDD-----------------KEFLESIMTGNDKIKEP 926

Query: 1629 FIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKY 1450
            FI+D R +NDDT VHFEVILSEENL+AA QEGL KKFKL TTISTSNMHLFD  GVIKKY
Sbjct: 927  FIKDYREHNDDTTVHFEVILSEENLQAAKQEGLMKKFKLTTTISTSNMHLFDPKGVIKKY 986

Query: 1449 DSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAE 1270
            D+PEQILE+FFHLRL+FYEKRKKV              KVRFIL VV GEIIV+NRKRA+
Sbjct: 987  DNPEQILEEFFHLRLEFYEKRKKVLLDNLELDLLKLDNKVRFILGVVKGEIIVSNRKRAD 1046

Query: 1269 LFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIG 1090
            LF EL QKGFTPFPKKTK ++ A+AGAT            +   GV+ASDYEYLLSM+IG
Sbjct: 1047 LFLELQQKGFTPFPKKTKTVEVAVAGATEDAEENEENSEVVSSKGVRASDYEYLLSMAIG 1106

Query: 1089 TLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQE 910
            TLT+EKVQELCA+ ++  HE++EL+  +PKTLW+RDLDALEK+LDEQD+ D +A+  ++E
Sbjct: 1107 TLTLEKVQELCADSNKLNHEVDELRKATPKTLWLRDLDALEKELDEQDKNDAQAEDARKE 1166

Query: 909  LRRKI--NTGAAVSRKAGPKKPRKNNATKGS-------XXXXXXXXXXXXGNVLEMGKPK 757
            L+ ++  + G  VSR+A PK PRK NA K +                   GNV E+ KPK
Sbjct: 1167 LKSRVMSDAGLKVSRQA-PKNPRKTNAKKNNNLEPVAESVAASVGSAMETGNVAEVAKPK 1225

Query: 756  PRGGQKKAAAK----TSVVESDDEDE-LIELKDRLAAYNLDSSPDQ-ASVETEELPQEVV 595
             RGG  KA+AK     ++ +SD++DE ++ELK+RLAAYNLDSSPDQ A++ETE       
Sbjct: 1226 GRGGPMKASAKKQDQLALADSDEDDEDVLELKERLAAYNLDSSPDQSAAMETEVAKPPAA 1285

Query: 594  TKKQPGKRAAARNTKSTLRISXXXXXXXDGERMQTI----IEDGSDEDFQVMEA-PKGKK 430
             KK P K AAA+    +   S       D   M TI     E+G+DEDF+   A P+G K
Sbjct: 1286 RKKGPSKMAAAQKKHPS---SYTENSDDDDVTMHTIEENMRENGNDEDFEPEAAGPRGGK 1342

Query: 429  TGAGRKPRNA---TAKDTTTANPRKRG-GTQGKTVLSQKLITDVLKSVKNA--SPEKKVR 268
             G GRKP  A   TA    TA  +KRG   +  ++LSQKLIT+VLK V N+  SPEKKVR
Sbjct: 1343 KG-GRKPAAAKVKTAAAKPTAATKKRGPANKQPSLLSQKLITEVLKPVDNSGVSPEKKVR 1401

Query: 267  KMRASPFNKKSGSVLGRAGGSAIE-----SEDSAGSLS-SGNLEAEMNGVRLTRNMPKRE 106
            KMRA PFN+KS SVLGR  G   E     SE+  GS S S +   E     + R  P+R 
Sbjct: 1402 KMRAFPFNRKSASVLGRVSGKVGEVSPKLSEEEPGSSSGSASTNTEEVSEVVARPRPQRA 1461

Query: 105  NRTKVTYVESGS 70
            NR K  YV S S
Sbjct: 1462 NRGKARYVLSDS 1473


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]
          Length = 1489

 Score = 1369 bits (3544), Expect = 0.0
 Identities = 718/1091 (65%), Positives = 839/1091 (76%), Gaps = 31/1091 (2%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSG+VE+LLSWAD+KQNK+LKKTDGTK+Q++TGI KL+DANDAGGRNSEKCTLILTEGDS
Sbjct: 400  KSGVVESLLSWADYKQNKDLKKTDGTKRQRLTGITKLEDANDAGGRNSEKCTLILTEGDS 459

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGR+HYGVFPLRGKLLNVR+A  +QI  NAEIQNIKQILGLQ GKEYDS
Sbjct: 460  AKALAMAGISVVGRNHYGVFPLRGKLLNVRDAQKKQILENAEIQNIKQILGLQQGKEYDS 519

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            +K LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKI  F+VEFITPIVKA+H++G+
Sbjct: 520  IKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHRNGR 579

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
            VLSFY+MPEYE+WKESL GNASGWSIKYYKGLGTST+KEGKEYF+ + +HKK F+W +E+
Sbjct: 580  VLSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEK 639

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DGDAIELAFSKKKIE RKNWLRQF+ GTYLD KEK IKYSDFVNKELILFS ADLQRSIP
Sbjct: 640  DGDAIELAFSKKKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIP 699

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S+VDGLKPGQRKILFC+FKRNF+KEAK+AQFSGYVSEHSAYHHGEQSL STI+GMAQDFV
Sbjct: 700  SMVDGLKPGQRKILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFV 759

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINL  PNGQFGTR++GGKD ASARYIYT LSPITRFLFPK        LNEDGQSI
Sbjct: 760  GSNNINLLLPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSI 819

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WYVP IPMVLVNGSEGIGTGWSS IPNYNPRD+IANVRRLLN E M+PMDPWYRGF+
Sbjct: 820  EPTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFR 879

Query: 1809 GTIEKS-AEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKE 1633
            GTIEK+   K+  V YT+ GIIEEV+ TTLRI+ELP+R WT DY +FL+ +M G DKIK+
Sbjct: 880  GTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKD 939

Query: 1632 PFIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKK 1453
            PFI+D + +NDDT VHFEVI+SEENL  A QEGL +KFKL T ISTSNMHLFDSNG IKK
Sbjct: 940  PFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKK 999

Query: 1452 YDSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRA 1273
            Y++PEQILE+FFHLRL+FYEKRK+V              KVRFIL VV GEIIV+NRKRA
Sbjct: 1000 YETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRA 1059

Query: 1272 ELFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSI 1093
            +LFHELHQKGFTPFPKK+K ++ A+AGAT            + KGGV+A+DYEYLLSM+I
Sbjct: 1060 DLFHELHQKGFTPFPKKSKSVEIAVAGATDDTEEAEENTDAVSKGGVRATDYEYLLSMAI 1119

Query: 1092 GTLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQ 913
            GTLT+EKVQELCA++D+    +++LK  +PK LW+ DLDALE++LDEQD+ D  A+  ++
Sbjct: 1120 GTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKNDARAEETRK 1179

Query: 912  ELRRKI--NTGAAVSRKAGPKKPRKNNATKGSXXXXXXXXXXXXGNVLEMG------KPK 757
            +L+ ++    G  VSR+A PK PRKNN    +             + +EM       KPK
Sbjct: 1180 QLKSRVMSEAGMKVSRQA-PKNPRKNNKKANNAEPAAETMDVSASSAMEMESVPEVVKPK 1238

Query: 756  PRGGQKKAAAK-----TSVVESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQ-EVV 595
             R   +KA AK     TSV++ +D+DE+ ELK+RLAAYNL+SSPD ++    E+PQ    
Sbjct: 1239 GRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAA 1298

Query: 594  TKKQPGKRAAARN--TKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVME--APKGKKT 427
             KK+P +RAAA+     S   IS                +D  DEDF+V E  A   KK 
Sbjct: 1299 RKKEPSRRAAAQKKPLASFTEISD---------------DDEDDEDFEVEEVSASDVKKK 1343

Query: 426  GAGRKP----RNATAKDTTTANPRKRGGT--QGKTVLSQKLITDVLKSVK--NASPEKKV 271
            G GRKP    + A AK    A   KRG    Q   +L Q L+T++ K  +    SPEKKV
Sbjct: 1344 G-GRKPAANAKAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLGISPEKKV 1402

Query: 270  RKMRASPFNKKSGSVLGRAG--GSAIESEDSAGSLSSGNLE-AEMNGVRL-TRNMPKREN 103
            RKMRASPFNKKSGSVLG  G      E+E+++GS S+ N    E N V +  R  P+REN
Sbjct: 1403 RKMRASPFNKKSGSVLGSTGEEDETAETEENSGSASTSNSSGGESNEVVMPARTRPQREN 1462

Query: 102  RTKVTYVESGS 70
            R +  YV S S
Sbjct: 1463 RVQTRYVVSDS 1473


>emb|CDP07797.1| unnamed protein product [Coffea canephora]
          Length = 1486

 Score = 1328 bits (3436), Expect = 0.0
 Identities = 701/1088 (64%), Positives = 831/1088 (76%), Gaps = 28/1088 (2%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSG+VENLLSWADFKQ+K+LKKTDGTK+Q+ITGI KL+DANDAGG+NS++CTLILTEGDS
Sbjct: 401  KSGVVENLLSWADFKQSKDLKKTDGTKRQRITGITKLEDANDAGGKNSDRCTLILTEGDS 460

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGR+ YGVFPLRGKLLNVREA+ +QI +NAEIQ IKQILGLQHGK YDS
Sbjct: 461  AKALAMAGISVVGRNFYGVFPLRGKLLNVREASHKQIMDNAEIQYIKQILGLQHGKVYDS 520

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            VK LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKI  F+VEFITPIVKA+HK+G+
Sbjct: 521  VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGR 580

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
            VLSFYTMPEYE+WKESLSGNA+GWSIKYYKGLGTST+KEGKEYF+ + +HKK FIW ++ 
Sbjct: 581  VLSFYTMPEYESWKESLSGNATGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFIWVDDN 640

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DG+AIELAFSKKKIEARKNWLRQFE GTYLD KEK IKYSDF+NKELILFS ADLQRSIP
Sbjct: 641  DGEAIELAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFINKELILFSLADLQRSIP 700

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S+VDGLKPGQRKILFC+FKRNFVKEAKVAQFSGYVSEHSAYHHGEQSL S I+GMAQDFV
Sbjct: 701  SMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASAIIGMAQDFV 760

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINL QPNGQFGTRN+GGKD ASARY+YT LSPITR LFPK        LNEDGQSI
Sbjct: 761  GSNNINLLQPNGQFGTRNQGGKDHASARYVYTRLSPITRSLFPKDDDILLDYLNEDGQSI 820

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WY+PIIPMVLVNGSEGIGTGWSSYIPNYNPRD+I N+RRLLN+EPM+PM+PWY+GF+
Sbjct: 821  EPTWYMPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIIGNIRRLLNNEPMEPMEPWYKGFR 880

Query: 1809 GTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEP 1630
            GTIEK+A KE G +YT+SGI+EEVD TT+R+TELP+R WT DY +FL+ +M G +K+K+P
Sbjct: 881  GTIEKTATKEAGASYTVSGIVEEVDETTIRVTELPVRKWTQDYKEFLESIMMGNEKVKDP 940

Query: 1629 FIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKY 1450
            FI++ R + DDT V+ ++I+SEENL  A QEGL KKFKL TTISTSNMHLFDS G+IKK+
Sbjct: 941  FIKEFRDHTDDTTVYLDIIMSEENLLMAKQEGLLKKFKLTTTISTSNMHLFDSQGIIKKF 1000

Query: 1449 DSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAE 1270
            D+PEQILE+FFHLRL+FYEKRKKV              KVRFILAVV G IIV+NRKRA+
Sbjct: 1001 DNPEQILEEFFHLRLEFYEKRKKVLLDNLQLELLKLDNKVRFILAVVEGSIIVSNRKRAD 1060

Query: 1269 LFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIG 1090
            LF EL +KGFTPFPKK K ++AA+AG+                 GV+ASDYEYL+SM+IG
Sbjct: 1061 LFLELKEKGFTPFPKK-KSVEAAVAGSIEDAEETEESSEVATSKGVRASDYEYLISMAIG 1119

Query: 1089 TLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQE 910
            +LT+EKVQELCA++D+ + E+++L   +PK+LW +DLDALE QLDEQD  D +A+  ++E
Sbjct: 1120 SLTLEKVQELCADRDKLKGEVDDLIKATPKSLWTKDLDALESQLDEQDISDAQAEAARKE 1179

Query: 909  LRRKI--NTGAAVSRKAGPKKPRKNNATKGS------XXXXXXXXXXXXGNVLEMGKPKP 754
            +R K   + G   +R+A PK PRK N    +                   NV+E+ KPK 
Sbjct: 1180 MRSKAMKDDGPKPTRQA-PKNPRKYNKKASNTEPTTEPMEISSSSALETNNVVEVAKPKG 1238

Query: 753  RGGQKKAAAKTSVV-------ESDDEDELIELKDRLAAYNL-DSSPDQASVETEELPQEV 598
            + G KKA A+           + +D+DE++ LKDRLAAYNL  SSPDQ+     E+P   
Sbjct: 1239 KAGPKKAPARKGKTFSVLRDEDDEDDDEVLALKDRLAAYNLGSSSPDQSETMETEIP--- 1295

Query: 597  VTKKQPGKRAAARNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAG 418
              K++P KRA    TK  L +S       D ++++  I D  D + +V  APK K    G
Sbjct: 1296 --KREPSKRA---TTKKPL-VSVTEISDDDDDQIE--ISDDEDFELEVEAAPKEK----G 1343

Query: 417  RKPRNATAKDTTTANPRKRG-GTQGKTVLSQKLITDVLK--SVKNASPEKKVRKMRASPF 247
            RK    +     TA P+KRG   +   ++ QKLIT+VLK   V   SPEKKVR+MR SPF
Sbjct: 1344 RKKTANSKAAKPTAAPKKRGQANKTSQLVGQKLITEVLKPADVSKISPEKKVRRMRPSPF 1403

Query: 246  NKKSGSVLGR--------AGGSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKR-ENRTK 94
            NKKSGSVL R            + E E+S  S +SG+ E E   V + R  P+R  NR K
Sbjct: 1404 NKKSGSVLERLSQQETDKISPESEEQEESPASNASGSTE-ESAQVVVPRARPRRGGNRGK 1462

Query: 93   VTYVESGS 70
              YV S S
Sbjct: 1463 AKYVMSDS 1470


>ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2-like [Eucalyptus grandis]
            gi|629094018|gb|KCW60013.1| hypothetical protein
            EUGRSUZ_H02748 [Eucalyptus grandis]
          Length = 1496

 Score = 1320 bits (3416), Expect = 0.0
 Identities = 687/1076 (63%), Positives = 813/1076 (75%), Gaps = 16/1076 (1%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSGIVE+LLSWA+FK +K+LKKTDG+K++ + GIPKL+DANDAGGRNS+KCTLILTEGDS
Sbjct: 417  KSGIVESLLSWANFKLSKDLKKTDGSKRENLRGIPKLEDANDAGGRNSDKCTLILTEGDS 476

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG+S VGRD YGVFPLRGKLLNVREA+  QI  N EIQ IKQILGLQ  K+YDS
Sbjct: 477  AKALAMAGLSVVGRDRYGVFPLRGKLLNVREASHSQIMENKEIQYIKQILGLQQNKDYDS 536

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            VK LRYGHLMIMTDQDHDGSHIKGLLINF+HSFWPSLLK+  F+VEFITPIVKA+HK+G+
Sbjct: 537  VKSLRYGHLMIMTDQDHDGSHIKGLLINFVHSFWPSLLKVPSFLVEFITPIVKATHKNGR 596

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
             LSFYTMPEYE+WKESL G+ SGWSIKYYKGLGTST+KEGK+YF+ +D HKK F+W ++Q
Sbjct: 597  ELSFYTMPEYESWKESLGGSGSGWSIKYYKGLGTSTSKEGKQYFQNLDMHKKDFVWVDDQ 656

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DGDAIELAFSKKKIEARK WLRQFE GTYLD KEK IKYSDFVNKELILFS ADLQRSIP
Sbjct: 657  DGDAIELAFSKKKIEARKTWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIP 716

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S+VDGLKPGQRKILFC+FKRNF+KEAKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+V
Sbjct: 717  SMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYV 776

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINL  PNGQFGTRN GGKD AS RY+YT LSP TRFLFPK        LNEDGQSI
Sbjct: 777  GSNNINLLMPNGQFGTRNMGGKDHASPRYVYTKLSPTTRFLFPKDDDNLLSYLNEDGQSI 836

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WY+PI+PMVLVNGSEGIGTGWSSYIPNYNPRD+IAN+RRLLN E M+PMDPWYRGF+
Sbjct: 837  EPTWYMPILPMVLVNGSEGIGTGWSSYIPNYNPRDIIANLRRLLNGEMMEPMDPWYRGFR 896

Query: 1809 GTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNG-TDKIKE 1633
            GTIEK+A KE GVTYT+ GIIEEVD TTLRITELPIR WT DY +FL+ +  G  DK K+
Sbjct: 897  GTIEKTATKEAGVTYTVCGIIEEVDDTTLRITELPIRRWTQDYREFLESLSTGEKDKAKD 956

Query: 1632 PFIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKK 1453
            PF+++ R Y+DD  VHFEV+L+EEN+  A QEGL KKFKL ++ISTSNMHLFD NGVIKK
Sbjct: 957  PFVKEFRQYSDDVTVHFEVMLTEENMMIAKQEGLLKKFKLTSSISTSNMHLFDPNGVIKK 1016

Query: 1452 YDSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRA 1273
            YDSPEQILE+FFHLRL+ YEKRKK+              KVRFIL VVHGEIIV+NRKRA
Sbjct: 1017 YDSPEQILEEFFHLRLECYEKRKKILLENLELKLVMLDNKVRFILGVVHGEIIVSNRKRA 1076

Query: 1272 ELFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSI 1093
            +LF EL  KGFTPF K+TK I+ A+AG+T              K GVKASDYEYLLSM+I
Sbjct: 1077 DLFQELQAKGFTPFRKETKTIETAVAGSTDDAEETEENSEPTTK-GVKASDYEYLLSMAI 1135

Query: 1092 GTLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQ 913
            G LT+EKVQELCA+KD+   E++ L+  +P+ LW+ DL ALE++LDEQ++ D +A+  ++
Sbjct: 1136 GALTLEKVQELCADKDKLVDEVDALRKATPENLWLEDLAALEEKLDEQEKMDAQAEETRK 1195

Query: 912  ELRRKINTGAAVSRKAGPKKPRK-----NNATKGSXXXXXXXXXXXXGNVLEMGKPKPRG 748
               +    G  VSR+A PKKPRK     NN    +            GN  ++ KPK   
Sbjct: 1196 ARSKANGVGTKVSRQA-PKKPRKNDTKANNPEAQAEVTQGSTVTLEAGNAADVAKPKRGA 1254

Query: 747  GQKKAAA----KTSVVESDDED-ELIELKDRLAAYNLDSSPDQASVETEELPQEVVTKKQ 583
            G +KA A    K++ V  DDED E+++LK+RLAAYNL+SSPD +S   +++P+  V +K+
Sbjct: 1255 GARKAPAPKPSKSASVSDDDEDFEMLDLKERLAAYNLESSPDNSSALEDKVPEIPVKEKE 1314

Query: 582  PGKRAAARNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVM--EAPKGKKTGAGRKP 409
            P KRAA R   S +               +    D  D+D++ +  EA   KK G GRKP
Sbjct: 1315 PSKRAATRKKPSVILSEISE---------EENSNDSGDDDYETVDSEAEVAKKKG-GRKP 1364

Query: 408  RNATAKDTTTANPRK-RGGTQGKTVLSQKLITDVLKSVKN--ASPEKKVRKMRASPFNKK 238
              A  K    A  +K +   Q     SQ+L+T++LK  ++   SPEKKVRKMRASPFNKK
Sbjct: 1365 SAAAKKSKPPAATKKGQANRQQARGTSQRLLTEMLKPAESTGVSPEKKVRKMRASPFNKK 1424

Query: 237  SGSVLGRAGGSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRTKVTYVESGS 70
            S S+LG+ G +   + +   S    N   ++  V   +  P+R NR + TYV S S
Sbjct: 1425 SSSLLGKEGKADSSTSEEMSSNPMSNDGEDVVEVAPPKRRPQRVNRKQTTYVLSDS 1480


>ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
            gi|508726241|gb|EOY18138.1| DNA topoisomerase 2 isoform 2
            [Theobroma cacao]
          Length = 1285

 Score = 1318 bits (3410), Expect = 0.0
 Identities = 693/1080 (64%), Positives = 819/1080 (75%), Gaps = 20/1080 (1%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            K G+V+NLLSWA+FK +K+LKKTDG K   I GIPKLDDAN+AGGRNS+KCTLILTEGDS
Sbjct: 208  KCGVVDNLLSWAEFKHSKDLKKTDGAKTGSIRGIPKLDDANEAGGRNSDKCTLILTEGDS 267

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALA+AG++ VGR+HYGVFPLRGKLLNVREA+ +Q+ +NAEIQN+K+ILGLQ GKEY +
Sbjct: 268  AKALAVAGLAVVGRNHYGVFPLRGKLLNVREASHKQLMDNAEIQNLKRILGLQQGKEYSN 327

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            VK LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+  FMVEFITPIVKA+HK+  
Sbjct: 328  VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKTKG 387

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
            VLSFY+MPEYE WKESL GNA GWSIKYYKGLGTST+KEGK+YF+ +D+H+K F+W +EQ
Sbjct: 388  VLSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQ 447

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DG+AIELAFSKKKIEARKNWLRQFE GT+LD  +K IKYS+F+NKELILFS ADLQRSIP
Sbjct: 448  DGEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIP 507

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S++DGLKPGQRKILFC+FKRNFVKEAKVAQFSGYVSEHSAYHHGEQSL STIVGMAQDFV
Sbjct: 508  SMIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFV 567

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINL  P GQFGTRN+GGKD ASARYI+T LSPITR+LFPK        LNEDGQSI
Sbjct: 568  GSNNINLLNPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSI 627

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRD++ANVRRLLN E M+PM PWYRGFK
Sbjct: 628  EPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFK 687

Query: 1809 GTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEP 1630
            G IEK+A KE GVTYTI+GIIEEVD TTLRITELP+R WT DY +FL+ ++ G D    P
Sbjct: 688  GNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND----P 743

Query: 1629 FIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKY 1450
            FI++ R Y+DDT V FEVIL+EEN+  A QEGL KKFKL TTISTSNMHLFDS G+IKKY
Sbjct: 744  FIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKY 803

Query: 1449 DSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAE 1270
            D+PEQILE+FFHLR +FYEKRKK+              KVRFIL VV GEIIVNNRKRA+
Sbjct: 804  DTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRAD 863

Query: 1269 LFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIG 1090
            LF EL  KGFTPFPKK K ++ A+AGAT              K G++ASDY+YLLSM+IG
Sbjct: 864  LFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAK-GLQASDYDYLLSMAIG 922

Query: 1089 TLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQE 910
            +LT+EKVQELCA++D+ + E+E+L+  +PK+LW++DLD LE QLDEQD K  +A+   + 
Sbjct: 923  SLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQD-KAAQAEEAAKL 981

Query: 909  LRRKINTGAAVSRKAGPKKPRKNNATKGSXXXXXXXXXXXXGNVLEMG-------KPKPR 751
            ++ +   G    R+A PK PRK N  + +             + +E         KPK R
Sbjct: 982  VKGRGEAGKRAQRQA-PKIPRKINKKEKNAETVTETTDISSSSAMETAETAPAAVKPKGR 1040

Query: 750  GGQKKAAAKTSVVESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVVTKKQPGKR 571
            GG +KA    S  + D++  + +L++RLA YNLDSSPD ++    E+PQ    KK+P KR
Sbjct: 1041 GGSRKAKKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKEPSKR 1100

Query: 570  AAARNTKSTLRISXXXXXXXDGERMQTIIE-DGSDEDFQVME-----APKGKKTGAGRKP 409
            AAA   K    +S         E  ++I E D +DED +V+E     AP GKK   GRKP
Sbjct: 1101 AAAARKKPATSLS---------EISESIGEIDINDEDLEVVEVAAAAAPAGKK--GGRKP 1149

Query: 408  -RNATAKDTTTANPRKRG-GTQGKTVLSQKLITDVLKSVKNA--SPEKKVRKMRASPFNK 241
              N+ A     A  +KRG    GK    QKL+T++LK  +++  SPEKKVRKMRASPFNK
Sbjct: 1150 AANSKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNK 1209

Query: 240  KSGSVLGRAG---GSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRTKVTYVESGS 70
            KSGSVLGR G    S  +SE++ GS S      E+  +   R  P+R NR + TYV S S
Sbjct: 1210 KSGSVLGRVGKELESTTDSEETFGSSSMSADTEEVTEIVPARPRPQRTNRKQTTYVLSDS 1269


>ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
            gi|508726240|gb|EOY18137.1| DNA topoisomerase 2 isoform 1
            [Theobroma cacao]
          Length = 1473

 Score = 1317 bits (3409), Expect = 0.0
 Identities = 693/1079 (64%), Positives = 819/1079 (75%), Gaps = 19/1079 (1%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            K G+V+NLLSWA+FK +K+LKKTDG K   I GIPKLDDAN+AGGRNS+KCTLILTEGDS
Sbjct: 397  KCGVVDNLLSWAEFKHSKDLKKTDGAKTGSIRGIPKLDDANEAGGRNSDKCTLILTEGDS 456

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALA+AG++ VGR+HYGVFPLRGKLLNVREA+ +Q+ +NAEIQN+K+ILGLQ GKEY +
Sbjct: 457  AKALAVAGLAVVGRNHYGVFPLRGKLLNVREASHKQLMDNAEIQNLKRILGLQQGKEYSN 516

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            VK LRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+  FMVEFITPIVKA+HK+  
Sbjct: 517  VKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKTKG 576

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
            VLSFY+MPEYE WKESL GNA GWSIKYYKGLGTST+KEGK+YF+ +D+H+K F+W +EQ
Sbjct: 577  VLSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQ 636

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DG+AIELAFSKKKIEARKNWLRQFE GT+LD  +K IKYS+F+NKELILFS ADLQRSIP
Sbjct: 637  DGEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIP 696

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S++DGLKPGQRKILFC+FKRNFVKEAKVAQFSGYVSEHSAYHHGEQSL STIVGMAQDFV
Sbjct: 697  SMIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFV 756

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINL  P GQFGTRN+GGKD ASARYI+T LSPITR+LFPK        LNEDGQSI
Sbjct: 757  GSNNINLLNPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSI 816

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRD++ANVRRLLN E M+PM PWYRGFK
Sbjct: 817  EPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFK 876

Query: 1809 GTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEP 1630
            G IEK+A KE GVTYTI+GIIEEVD TTLRITELP+R WT DY +FL+ ++ G D    P
Sbjct: 877  GNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND----P 932

Query: 1629 FIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKY 1450
            FI++ R Y+DDT V FEVIL+EEN+  A QEGL KKFKL TTISTSNMHLFDS G+IKKY
Sbjct: 933  FIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKY 992

Query: 1449 DSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAE 1270
            D+PEQILE+FFHLR +FYEKRKK+              KVRFIL VV GEIIVNNRKRA+
Sbjct: 993  DTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRAD 1052

Query: 1269 LFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIG 1090
            LF EL  KGFTPFPKK K ++ A+AGAT              K G++ASDY+YLLSM+IG
Sbjct: 1053 LFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAK-GLQASDYDYLLSMAIG 1111

Query: 1089 TLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQE 910
            +LT+EKVQELCA++D+ + E+E+L+  +PK+LW++DLD LE QLDEQD K  +A+   + 
Sbjct: 1112 SLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQD-KAAQAEEAAKL 1170

Query: 909  LRRKINTGAAVSRKAGPKKPRKNNATKGSXXXXXXXXXXXXGNVLEMG------KPKPRG 748
            ++ +   G    R+A PK PRK N  + +             + +E        KPK RG
Sbjct: 1171 VKGRGEAGKRAQRQA-PKIPRKINKKEKNAETVTETTDISSSSAMETETAPAAVKPKGRG 1229

Query: 747  GQKKAAAKTSVVESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVVTKKQPGKRA 568
            G +KA    S  + D++  + +L++RLA YNLDSSPD ++    E+PQ    KK+P KRA
Sbjct: 1230 GSRKAKKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKEPSKRA 1289

Query: 567  AARNTKSTLRISXXXXXXXDGERMQTIIE-DGSDEDFQVME-----APKGKKTGAGRKP- 409
            AA   K    +S         E  ++I E D +DED +V+E     AP GKK   GRKP 
Sbjct: 1290 AAARKKPATSLS---------EISESIGEIDINDEDLEVVEVAAAAAPAGKK--GGRKPA 1338

Query: 408  RNATAKDTTTANPRKRG-GTQGKTVLSQKLITDVLKSVKNA--SPEKKVRKMRASPFNKK 238
             N+ A     A  +KRG    GK    QKL+T++LK  +++  SPEKKVRKMRASPFNKK
Sbjct: 1339 ANSKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRASPFNKK 1398

Query: 237  SGSVLGRAG---GSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRTKVTYVESGS 70
            SGSVLGR G    S  +SE++ GS S      E+  +   R  P+R NR + TYV S S
Sbjct: 1399 SGSVLGRVGKELESTTDSEETFGSSSMSADTEEVTEIVPARPRPQRTNRKQTTYVLSDS 1457


>gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984168|gb|AAN85208.1|
            DNA topoisomerase II [Nicotiana tabacum]
          Length = 1482

 Score = 1303 bits (3371), Expect = 0.0
 Identities = 685/1082 (63%), Positives = 815/1082 (75%), Gaps = 24/1082 (2%)
 Frame = -3

Query: 3243 GIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDSAK 3064
            GIVE LLSWADFK +K+LKKTDG K +K+  + KL+DANDAGGRNSEKCTLILTEGDSAK
Sbjct: 399  GIVETLLSWADFKNSKDLKKTDGKKSEKVK-VEKLEDANDAGGRNSEKCTLILTEGDSAK 457

Query: 3063 ALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDSVK 2884
            ALAMAG+S VGRDHYGVFPLRGKLLNVREA+ +Q+  N EI+ IK+ILGLQ GKEYDSVK
Sbjct: 458  ALAMAGISVVGRDHYGVFPLRGKLLNVREASHKQVSENKEIEAIKKILGLQTGKEYDSVK 517

Query: 2883 GLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGKVL 2704
             LRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+  F++EFITPIVKA+HKSGK+L
Sbjct: 518  SLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFLIEFITPIVKATHKSGKIL 577

Query: 2703 SFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQDG 2524
            SFYTMPEYE+W++SL  N+SGWSIKYYKGLGTST+KEGKEYF+ + +H+K FIWA+ QDG
Sbjct: 578  SFYTMPEYESWRKSLGANSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQDG 637

Query: 2523 DAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIPSV 2344
            ++IELAFSKKKIEARKNWLRQFE GT+LD KEK I Y++FVNKELILFS ADLQRSIPS+
Sbjct: 638  ESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSM 697

Query: 2343 VDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFVGS 2164
            +DGLKPGQRKILFCAFKRNFVKEAKV+QFSGYVSEHSAYHHGEQSL STI+GMAQD+VGS
Sbjct: 698  LDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGS 757

Query: 2163 NNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSIEP 1984
            NN+NL QPNGQFGTRN GGKD AS+RYIYT LSPI RFLFPK        LNEDGQ IEP
Sbjct: 758  NNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKEDDTIHDYLNEDGQYIEP 817

Query: 1983 AWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFKGT 1804
             WYVPI+PMVL+NGSEGIGTGWSSY+PNYNPRD++ANVRRLLN EPM+PMDPWY+GFKGT
Sbjct: 818  TWYVPIVPMVLINGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDEPMEPMDPWYKGFKGT 877

Query: 1803 IEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEPFI 1624
            IEK+A KE G TYT++GIIEEV+ TTLRI+ELP+R WT DY QFL+ M    DK K+PFI
Sbjct: 878  IEKTATKEAGATYTVTGIIEEVNETTLRISELPVRRWTEDYKQFLESMTVSNDKAKDPFI 937

Query: 1623 QDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKYDS 1444
            ++ RAY D+ +V FEVI+SEENL  A QEGL KKFKL TTISTSNMHLFDSNG IKKYD+
Sbjct: 938  KEVRAYGDENSVCFEVIMSEENLILAQQEGLLKKFKLATTISTSNMHLFDSNGKIKKYDN 997

Query: 1443 PEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAELF 1264
            PE ILE+F+H+RL++YEKRKK               KV+FIL VV  EIIVNNRKRA+L 
Sbjct: 998  PEDILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKVEIIVNNRKRADLL 1057

Query: 1263 HELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIGTL 1084
             EL +KGFTPFPKK K ++A +A  +           E +  GV+A DY+YLLSM IGTL
Sbjct: 1058 LELKEKGFTPFPKK-KAVEAVVADTS----DDAEDSEEELNRGVRAGDYDYLLSMPIGTL 1112

Query: 1083 TMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQELR 904
            T+EKVQELCAE+D+   E+E++++ +PK LW++DLD LEKQLDEQD+ D++A+  +++++
Sbjct: 1113 TLEKVQELCAERDQLNGEVEDMRNATPKLLWLKDLDVLEKQLDEQDKIDIQAEEAREKIK 1172

Query: 903  RKINTGAAVSRKAGPKKPRKN-------NATKGSXXXXXXXXXXXXGNVLEMGKPKPRGG 745
            +K+   A +  KA   KPRKN        +T                NV E+ KPK RGG
Sbjct: 1173 KKVMNAAGL--KAPKPKPRKNVKKASVVESTAEPMDRVSCFNSGNRSNVTEVVKPKARGG 1230

Query: 744  QKKAAAKTSVV-----ESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVVTKKQP 580
             KKA AK   +     E +++DE++ LKDRLAAYNL+SSPD  S E  E       KK P
Sbjct: 1231 SKKAPAKAKPIAVEDEEEEEDDEVLALKDRLAAYNLNSSPDH-SAEAMETEAPKAQKKAP 1289

Query: 579  GKRAAARNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRKPRNA 400
             ++AAA+  K TL          +GE     IE   D++ +   A  GKK G GRKP  A
Sbjct: 1290 TRKAAAK--KKTL---PSIADVSEGE---DEIEISDDDESEPEVAVGGKKKG-GRKPATA 1340

Query: 399  TAKDTTTANPRKRGGTQGKTV--LSQKLITDVLK---SVKNASPEKKVRKMRASPFNKKS 235
             A       P K+ G   K    + QKLIT +LK   +  N+SPEKKVRKMRASPFN+KS
Sbjct: 1341 KAAPAAAKQPPKKRGPANKQAVGIGQKLITSILKPAENTDNSSPEKKVRKMRASPFNEKS 1400

Query: 234  GSVLGRAGGSAIESEDSAGSLSS-GNLEAEMN------GVRLTRNMPKRENRTKVTYVES 76
            G+VLG+  GS ++  + A  +SS G+LE E+N        R+TR         K TYV S
Sbjct: 1401 GAVLGKNKGSTLQENEDASPVSSLGSLEDEVNEAVVAPKARVTRG-------KKTTYVIS 1453

Query: 75   GS 70
             S
Sbjct: 1454 DS 1455


>ref|XP_009630917.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Nicotiana
            tomentosiformis]
          Length = 1486

 Score = 1300 bits (3363), Expect = 0.0
 Identities = 686/1087 (63%), Positives = 815/1087 (74%), Gaps = 29/1087 (2%)
 Frame = -3

Query: 3243 GIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDSAK 3064
            GIVE LLSWADFK +K+LKKTDG K +K+  + KL+DANDAGGRNS+KCTLILTEGDSAK
Sbjct: 399  GIVETLLSWADFKNSKDLKKTDGKKSEKVK-VEKLEDANDAGGRNSDKCTLILTEGDSAK 457

Query: 3063 ALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDSVK 2884
            ALAMAG+S VGRDHYGVFPLRGKLLNVREA+ +Q+  N EI+ IK+ILGLQ GKEY+SVK
Sbjct: 458  ALAMAGISVVGRDHYGVFPLRGKLLNVREASHKQVSENKEIEAIKKILGLQTGKEYESVK 517

Query: 2883 GLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGKVL 2704
             LRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+  F++EFITPIVKA+HKSGK+L
Sbjct: 518  SLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFLIEFITPIVKATHKSGKIL 577

Query: 2703 SFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQDG 2524
            SFYTMPEYE+W++SL  N+SGWSIKYYKGLGTST+KEGKEYF+ + +H+K FIWA+ QDG
Sbjct: 578  SFYTMPEYESWRKSLGANSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQDG 637

Query: 2523 DAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIPSV 2344
            ++IELAFSKKKIEARKNWLRQFE GT+LD KEK I Y++FVNKELILFS ADLQRSIPS+
Sbjct: 638  ESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSM 697

Query: 2343 VDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFVGS 2164
            +DGLKPGQRKILFCAFKRNFVKEAKV+QFSGYVSEHSAYHHGEQSL STI+GMAQD+VGS
Sbjct: 698  LDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGS 757

Query: 2163 NNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSIEP 1984
            NN+NL QPNGQFGTRN GGKD AS+RYIYT LSPI RFLFPK        LNEDGQ IEP
Sbjct: 758  NNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKEDDTILDYLNEDGQYIEP 817

Query: 1983 AWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFKGT 1804
             WYVPI+PMVL+NGSEGIGTGWSSY+PNYNPRD++ANVRRLLN EPM+PMDPWY+GFKGT
Sbjct: 818  TWYVPIVPMVLINGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDEPMEPMDPWYKGFKGT 877

Query: 1803 IEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEPFI 1624
            IEK+A KE G TYT++GIIEEV+ TTLRI+ELP+R WT DY QFL+ M    DK K+PFI
Sbjct: 878  IEKTATKEAGATYTVTGIIEEVNETTLRISELPVRRWTEDYKQFLESMTVSNDKAKDPFI 937

Query: 1623 QDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKYDS 1444
            ++ RAY D+ +V FEVI+SEENL  A QEGL KKFKL TTISTSNMHLFDSNG IKKYD+
Sbjct: 938  KEVRAYGDENSVCFEVIMSEENLILAQQEGLLKKFKLATTISTSNMHLFDSNGKIKKYDN 997

Query: 1443 PEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAELF 1264
            PE ILE+F+H+RL++YEKRKK               KV+FIL VV GEIIVNNRKRA+L 
Sbjct: 998  PEDILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKGEIIVNNRKRADLL 1057

Query: 1263 HELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIGTL 1084
             EL +KGFTPFPKK K ++A +A  +           E +  GV+A DY+YLLSM IGTL
Sbjct: 1058 LELKEKGFTPFPKK-KAVEAVVADTS----DDAEDSEEELNRGVRAGDYDYLLSMPIGTL 1112

Query: 1083 TMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQELR 904
            T+EKVQELCAE+D+   E+E++++ +PK LW++DLD LEKQLDEQD+ D++A+  +++++
Sbjct: 1113 TLEKVQELCAERDKLNGEVEDMRNATPKLLWLKDLDVLEKQLDEQDKIDIQAEEAREKIK 1172

Query: 903  RKINTGAAVSRKAGPKKPRKNNATKGS------------XXXXXXXXXXXXGNVLEMGKP 760
            +K+   A +  KA   KPRK N  K S                         NV E+ KP
Sbjct: 1173 KKVMNAAGL--KAPKPKPRK-NVKKASVVESTAEPMDXVSCFNSGNRLVSNSNVTEVVKP 1229

Query: 759  KPRGGQKKAAAKTSVV-----ESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVV 595
            K RGG KKA AK   +     E +++DE++ LKDRLAAYNL+SSPD  S E  E      
Sbjct: 1230 KARGGSKKAPAKAKPIAVEDEEEEEDDEVLALKDRLAAYNLNSSPDH-SAEAMETEAPKA 1288

Query: 594  TKKQPGKRAAARNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGR 415
             KK P ++AAA+  K TL          +GE     IE   D++ +   A  GKK G GR
Sbjct: 1289 QKKAPTRKAAAK--KKTL---PSIADVSEGE---DEIEISDDDESEPEVAVGGKKKG-GR 1339

Query: 414  KPRNATAKDTTTANPRKRGGTQGKTV--LSQKLITDVLK---SVKNASPEKKVRKMRASP 250
            KP  A A       P K+ G   K    + QKLIT +LK   +  N+SPEKKVRKMRASP
Sbjct: 1340 KPATAKAAPAAAKQPPKKRGPANKQAVGIGQKLITSILKPAENTDNSSPEKKVRKMRASP 1399

Query: 249  FNKKSGSVLGRAGGSAIESEDSAGSLSS-GNLEAEMN------GVRLTRNMPKRENRTKV 91
            FNKKSG+VLG+  GS  +  + A  +SS G+LE E+N        R+TR         K 
Sbjct: 1400 FNKKSGAVLGKNKGSTSQENEDASPVSSLGSLEDEVNEAVVAPKARVTRG-------KKT 1452

Query: 90   TYVESGS 70
            TYV S S
Sbjct: 1453 TYVISDS 1459


>ref|XP_009800897.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Nicotiana
            sylvestris]
          Length = 1474

 Score = 1298 bits (3358), Expect = 0.0
 Identities = 688/1086 (63%), Positives = 818/1086 (75%), Gaps = 28/1086 (2%)
 Frame = -3

Query: 3243 GIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDSAK 3064
            GIVE LLSWADFK +K+LKKTDG K +K+  + KL+DANDAGGRNSEKCTLILTEGDSAK
Sbjct: 399  GIVETLLSWADFKNSKDLKKTDGKKSEKVK-VEKLEDANDAGGRNSEKCTLILTEGDSAK 457

Query: 3063 ALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDSVK 2884
            ALAMAG+S VGRDHYGVFPLRGKLLNVREA+ +Q+  N EI+ IK+ILGLQ GKEYDSVK
Sbjct: 458  ALAMAGISVVGRDHYGVFPLRGKLLNVREASHKQVSENKEIEAIKKILGLQTGKEYDSVK 517

Query: 2883 GLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGKVL 2704
             LRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+  F++EFITPIVKA+HKSGK+L
Sbjct: 518  SLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFLIEFITPIVKATHKSGKIL 577

Query: 2703 SFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQDG 2524
            SFYTMPEYE+W++SL  N+SGWSIKYYKGLGTST+KEGKEYF+ + +H+K FIWA+ QDG
Sbjct: 578  SFYTMPEYESWRKSLGANSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQDG 637

Query: 2523 DAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIPSV 2344
            ++IELAFSKKKIEARKNWLRQFE GT+LD KEK I Y++FVNKELILFS ADLQRSIPS+
Sbjct: 638  ESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSM 697

Query: 2343 VDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFVGS 2164
            +DGLKPGQRKILFCAFKRNFVKEAKV+QFSGYVSEHSAYHHGEQSL STI+GMAQD+VGS
Sbjct: 698  LDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGS 757

Query: 2163 NNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSIEP 1984
            NN+NL QPNGQFGTRN GGKD AS+RYIYT LSPI RFLFPK        LNEDGQSIEP
Sbjct: 758  NNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKEDDTILDYLNEDGQSIEP 817

Query: 1983 AWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFKGT 1804
             WYVPI+PMVL+NGSEGIGTGWSSY+PNYNPRD++ANVRRLLN EPM+PMDPWY+GFKGT
Sbjct: 818  TWYVPIVPMVLINGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDEPMEPMDPWYKGFKGT 877

Query: 1803 IEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEPFI 1624
            IEK+A KE G TYT++GIIEE++ TTLRI+ELP+R WT DY QFL+ M    DK K+PFI
Sbjct: 878  IEKTATKEAGATYTVTGIIEELNETTLRISELPVRRWTEDYKQFLESMTVSNDKAKDPFI 937

Query: 1623 QDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKYDS 1444
            ++ RAY D+ +V FEVILSEENL  A QEGL KKFKL TTISTSNMHLFDS G IKKYD+
Sbjct: 938  KEVRAYGDENSVCFEVILSEENLILAQQEGLLKKFKLATTISTSNMHLFDSKGKIKKYDN 997

Query: 1443 PEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAELF 1264
            PE ILE+F+H+RL++YEKRK+               KV+FIL VV GEIIVNNRKRA+L 
Sbjct: 998  PEDILEEFYHVRLEYYEKRKRALLEILELELLRIENKVKFILGVVKGEIIVNNRKRADLL 1057

Query: 1263 HELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIGTL 1084
             EL +KGFTPFPKK K ++A +A  +           E +  GV+A DY+YLLSM+IGTL
Sbjct: 1058 LELKEKGFTPFPKK-KAVEAVVADTS----DDAEDSEEELNRGVRAGDYDYLLSMAIGTL 1112

Query: 1083 TMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQELR 904
            T+EKVQELCAE+D+   E+E++++ +PK LW++DLD LEKQLDEQD+ D++ +  +++++
Sbjct: 1113 TLEKVQELCAERDKLNGEVEDMRNATPKLLWLKDLDVLEKQLDEQDKIDIQTEEAREKIK 1172

Query: 903  RKINTGAAVSRKAGPKKPRKNNATKGS------------XXXXXXXXXXXXGNVLEMGKP 760
            +K+   A +  KA   KPRK N  K S                         NV E+ KP
Sbjct: 1173 KKVMNAAGL--KAPKPKPRK-NVKKASVVESTAEPMDXVSCFNKGNRLVSNSNVTEVVKP 1229

Query: 759  KPRGGQKKAAAKTSVV----ESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVVT 592
            K RGG KKA AK   +    E +++DE++ LKDRLAAYNL+SSPD  S E  E       
Sbjct: 1230 KARGGSKKAPAKAKPIAVEDEEEEDDEVLALKDRLAAYNLNSSPDH-STEGMETEAPKAQ 1288

Query: 591  KKQPGKRAAARNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRK 412
            KK P ++AAA+  K TL          +GE     IE   D++F+   A  GKK G GRK
Sbjct: 1289 KKAPTRKAAAK--KKTL---PSIADVSEGE---DEIEISDDDEFEPEVAVGGKKKG-GRK 1339

Query: 411  PRNATAKDTTTANPRKRG-GTQGKTVLSQKLITDVLK---SVKNASPEKKVRKMRASPFN 244
               A  K      P+KRG G +    + QKLIT +LK   +  N+SPEKKVRKMRASPFN
Sbjct: 1340 AAPAATKQP----PKKRGPGNKQSVGIGQKLITSILKPAENTDNSSPEKKVRKMRASPFN 1395

Query: 243  KKSGSVLG--RAGGSAIESEDSAGSLSSGNLEAEMN------GVRLTRNMPKRENRTKVT 88
            KKSGSVLG  + G ++ E+ED +   S G+LE E+N        R+TR         K T
Sbjct: 1396 KKSGSVLGKNKEGSTSQENEDVSPVSSLGSLEDEVNEAVVAPKARVTRG-------KKTT 1448

Query: 87   YVESGS 70
            YV S S
Sbjct: 1449 YVISDS 1454


>ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum tuberosum]
          Length = 1485

 Score = 1296 bits (3355), Expect = 0.0
 Identities = 684/1076 (63%), Positives = 816/1076 (75%), Gaps = 18/1076 (1%)
 Frame = -3

Query: 3243 GIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDSAK 3064
            GIV++LLSWADFK +K+LKKTDG K  K+  + KL+DANDAGGRNS+KCTLILTEGDSAK
Sbjct: 400  GIVDSLLSWADFKNSKDLKKTDGKKSDKVK-VEKLEDANDAGGRNSDKCTLILTEGDSAK 458

Query: 3063 ALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDSVK 2884
            ALAMAG+S VGRDHYGVFPLRGKLLNVREA+ +Q+  N EI++IK+ILGLQ GKEY+SVK
Sbjct: 459  ALAMAGISVVGRDHYGVFPLRGKLLNVREASHKQVSENKEIESIKKILGLQTGKEYESVK 518

Query: 2883 GLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGKVL 2704
             LRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+  F+VEFITPIVKA+HKSG++L
Sbjct: 519  SLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFLVEFITPIVKATHKSGRIL 578

Query: 2703 SFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQDG 2524
            +FYTMPEYEAW+ SL   +SGWSIKYYKGLGTST+KEGKEYF+ + +H+K FIWA+ QDG
Sbjct: 579  AFYTMPEYEAWRRSLGATSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQDG 638

Query: 2523 DAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIPSV 2344
            ++IELAFSKKKIEARKNWLRQFE GT+LD KEK I Y++FVNKELILFS ADLQRSIPS+
Sbjct: 639  ESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSM 698

Query: 2343 VDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFVGS 2164
            +DGLKPGQRKILFCAFKRNFVKEAKV+QFSGYVSEHSAYHHGEQSL STI+GMAQD+VGS
Sbjct: 699  LDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGS 758

Query: 2163 NNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSIEP 1984
            NN+NL QPNGQFGTRN GGKD AS+RYIYT LSPI RFLFPK        LNEDGQSIEP
Sbjct: 759  NNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKDDDTVLDYLNEDGQSIEP 818

Query: 1983 AWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFKGT 1804
             WY+PIIPMVLVNGSEGIGTGWSSY+PNYNPRD++ANVRRLLN E M+PMDPWY+GFKGT
Sbjct: 819  TWYIPIIPMVLVNGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDELMEPMDPWYKGFKGT 878

Query: 1803 IEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEPFI 1624
            IEK+A KETG TYT++GIIEE   TTLRI+ELP+R WT DY QFL+ M   TDK K+ FI
Sbjct: 879  IEKTATKETGATYTVTGIIEEFSETTLRISELPVRRWTEDYKQFLESMTVSTDKSKDAFI 938

Query: 1623 QDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKYDS 1444
            ++ RAY D+ +V FEVI+SEENL  A QEGL KKFKL TTISTSNMHLFDS G IKKYD+
Sbjct: 939  KEVRAYGDENSVCFEVIMSEENLLLAQQEGLLKKFKLTTTISTSNMHLFDSKGKIKKYDA 998

Query: 1443 PEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAELF 1264
            PE+ILE+F+H+RL++YEKRKK               KVRFIL VV GEIIVNNRKRA+L 
Sbjct: 999  PEEILEEFYHVRLEYYEKRKKTLLEILELELLRIENKVRFILGVVKGEIIVNNRKRADLL 1058

Query: 1263 HELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIGTL 1084
             EL  KGFTPFPKK K ++A +A +T           E  K GV+ASDY+YLLSM+IGTL
Sbjct: 1059 LELKNKGFTPFPKK-KPVEAVVADSTDDAEDSEESPEESNK-GVRASDYDYLLSMAIGTL 1116

Query: 1083 TMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQELR 904
            T+EKVQELCA++D+   E+E++++ +PK LWM+DLD L+KQLDEQD+ D++ +  +++L+
Sbjct: 1117 TLEKVQELCADRDKLNAEVEDMRNATPKDLWMKDLDVLDKQLDEQDKLDIQTEEAREKLK 1176

Query: 903  RKINTGAAVSRKAGPKKPRKNNA---TKGSXXXXXXXXXXXXGNVLEMGKPKPR-GGQKK 736
            +K+   A  + K  P+K  K  A   +                NV E+ KPK R GG KK
Sbjct: 1177 KKVMNAAGKAPKPKPRKTTKKAAVVESTAEPMDVSVGSMAETANVTEVAKPKGRGGGSKK 1236

Query: 735  AAAKTS---VVESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVVTKKQPGKRAA 565
            A AK     V + ++EDE++ LKDRLAAYNL+SSPD++ V   E P+     K P KRAA
Sbjct: 1237 APAKAKPVVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEAPK--AQTKAPAKRAA 1294

Query: 564  ARN--TKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRKPRNATAK 391
            A+     ST  +S            +  IE   D +F    A  GKK G GRKP  A AK
Sbjct: 1295 AQKKALPSTPDVSEG----------EDEIEISDDNEFAPEVAVGGKKKG-GRKP--AAAK 1341

Query: 390  DTTTANPRKRGGTQGKTVLS--QKLITDVLKSVKNA--SPEKKVRKMRASPFNKKSGSVL 223
                  P K+     K   S  Q+LIT VLK  ++A  SP++KVRKMR SPFNKKSG+V+
Sbjct: 1342 AAAAPKPPKKRAPANKQSQSVGQRLITQVLKPAEDAGVSPDRKVRKMRESPFNKKSGAVM 1401

Query: 222  GR----AGGSAIESEDSAGSLSSGNLEAEMNGVRLT-RNMPKRENRTKVTYVESGS 70
            GR    +  ++ ESE S    S G+LE E++ V +  +  P+R NRTK TYV S S
Sbjct: 1402 GRNTSSSSSTSHESEVSPPIPSLGSLEEEVSEVVVAPKARPQRANRTKTTYVISDS 1457


>ref|XP_010324649.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Solanum lycopersicum]
          Length = 1478

 Score = 1281 bits (3314), Expect = 0.0
 Identities = 674/1072 (62%), Positives = 814/1072 (75%), Gaps = 14/1072 (1%)
 Frame = -3

Query: 3243 GIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDSAK 3064
            GIV++LLSWADFK +K+LKKTDG K  K+  + KL+DANDAGGRNS+KCTLILTEGDSAK
Sbjct: 400  GIVDSLLSWADFKLSKDLKKTDGKKSDKVK-VEKLEDANDAGGRNSDKCTLILTEGDSAK 458

Query: 3063 ALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDSVK 2884
            ALAMAG+S VGRDHYGVFPLRGKLLNVREA+ +Q+  N EI++IK+ILGLQ GKEYDSVK
Sbjct: 459  ALAMAGISVVGRDHYGVFPLRGKLLNVREASHKQVSENKEIESIKKILGLQTGKEYDSVK 518

Query: 2883 GLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGKVL 2704
             LRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+  F+VEFITPIVKA+HKSG++L
Sbjct: 519  SLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFLVEFITPIVKATHKSGRIL 578

Query: 2703 SFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQDG 2524
            +FYTMPEYEAW+ SL   +SGWSIKYYKGLGTST+KEGKEYF+ + +H+K F+WA+ QDG
Sbjct: 579  AFYTMPEYEAWRRSLGATSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFVWADNQDG 638

Query: 2523 DAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIPSV 2344
            ++IELAFSKKKIEARKNWLRQFE GT+LD KEK I Y++FVNKELILFS ADLQRSIPS+
Sbjct: 639  ESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSM 698

Query: 2343 VDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFVGS 2164
            +DGLKPGQRKILFCAFKRNFVKEAKV+QFSGYVSEHSAYHHGEQSL STI+GMAQD+VGS
Sbjct: 699  LDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGS 758

Query: 2163 NNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSIEP 1984
            NN+NL QPNGQFGTRN GGKD AS+RYIYT LSPI RFLFPK        LNEDGQSIEP
Sbjct: 759  NNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKDDDTILDYLNEDGQSIEP 818

Query: 1983 AWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFKGT 1804
             WYVP+IP VLVNGSEGIGTGWSSY+PNYNPRD++ANVRRLLN E M+PMDPWY+GFKG 
Sbjct: 819  TWYVPVIPTVLVNGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDELMEPMDPWYKGFKGK 878

Query: 1803 IEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEPFI 1624
            IEK+A KETG TYT++GIIEEV  TTLRI+ELP+R WT DY QFL+ M   TDK K+ FI
Sbjct: 879  IEKTATKETGATYTVTGIIEEVSETTLRISELPVRRWTEDYKQFLESMTVSTDKAKDSFI 938

Query: 1623 QDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKYDS 1444
            ++ RAY D+ +V FEVI+SE+NL  A QEGL KKFKL TTISTSNMHLFDS G IKKYD+
Sbjct: 939  KEVRAYGDENSVCFEVIMSEDNLLLAQQEGLLKKFKLTTTISTSNMHLFDSKGKIKKYDA 998

Query: 1443 PEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAELF 1264
            PE+ILE+F+H+RL++YEKRKK               KV+FIL VV GEIIVNNRKRAEL 
Sbjct: 999  PEEILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKGEIIVNNRKRAELL 1058

Query: 1263 HELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIGTL 1084
             EL  KGFTPFPKK K ++A +A +T           E  + GV+ASDY+YLLSM+IGTL
Sbjct: 1059 LELKNKGFTPFPKK-KPVEAVVADSTDDADDSEESPEESSR-GVRASDYDYLLSMAIGTL 1116

Query: 1083 TMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQELR 904
            T+EKVQELCA++D+   E+E++++ +PK LWM+DLD L+KQLDEQD+ D++ +  +++L+
Sbjct: 1117 TLEKVQELCADRDKLNAEVEDMRNATPKHLWMKDLDVLDKQLDEQDKIDIQTEEAREKLK 1176

Query: 903  RKINTGAAVSRKAGPK-KPRKNN---ATKGSXXXXXXXXXXXXGNVLEMGKPKPRGGQKK 736
            +K+   A    KA PK KPRK N    +                NV E+ KPK RG   K
Sbjct: 1177 KKVMNAAG---KAAPKPKPRKTNKKAESTAESMDVSFGSTAETANVSEVVKPKGRGRPAK 1233

Query: 735  AAAKTSVVESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVVTKKQPGKRAAARN 556
             A    V + ++EDE++ LKDRLAAYNL+SSPD++ V   E+P+     K P KRAAA+ 
Sbjct: 1234 QAKPIVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEVPK--AQTKAPAKRAAAQK 1291

Query: 555  --TKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRKPRNATAKDTT 382
                ST  +S       DGE    I     D++F+   A  GKK G GRKP  A A    
Sbjct: 1292 KALPSTPDVS-------DGEDAIEI----DDDEFEPAAAVGGKKKG-GRKPAAAKAAAAP 1339

Query: 381  TANPRKRGGTQGKTVLSQKLITDVLKSVKNA--SPEKKVRKMRASPFNKKSGSVLGR--- 217
                +K         + Q+LIT VLK  ++A  SP++KVRKMRASPFNKKSG+V+G+   
Sbjct: 1340 KPPGKKAPANNQSQSVGQRLITQVLKPAEDAGVSPDRKVRKMRASPFNKKSGAVMGKNTS 1399

Query: 216  -AGGSAIESEDSAGSLSS-GNLEAEMNGVRLT-RNMPKRENRTKVTYVESGS 70
             +  S+ ESE+ +  + S G+L+ E++ V +  +  P+R  +   TYV S S
Sbjct: 1400 SSSTSSHESEEVSPLIPSLGSLDEEVSEVVVAPKARPQRATKKTTTYVISDS 1451


>ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Solanum lycopersicum]
          Length = 1477

 Score = 1279 bits (3309), Expect = 0.0
 Identities = 677/1073 (63%), Positives = 817/1073 (76%), Gaps = 15/1073 (1%)
 Frame = -3

Query: 3243 GIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDSAK 3064
            GIV++LLSWADFK +K+LKKTDG K  K+  + KL+DANDAGGRNS+KCTLILTEGDSAK
Sbjct: 400  GIVDSLLSWADFKLSKDLKKTDGKKSDKVK-VEKLEDANDAGGRNSDKCTLILTEGDSAK 458

Query: 3063 ALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDSVK 2884
            ALAMAG+S VGRDHYGVFPLRGKLLNVREA+ +Q+  N EI++IK+ILGLQ GKEYDSVK
Sbjct: 459  ALAMAGISVVGRDHYGVFPLRGKLLNVREASHKQVSENKEIESIKKILGLQTGKEYDSVK 518

Query: 2883 GLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGKVL 2704
             LRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+  F+VEFITPIVKA+HKSG++L
Sbjct: 519  SLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFLVEFITPIVKATHKSGRIL 578

Query: 2703 SFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQDG 2524
            +FYTMPEYEAW+ SL   +SGWSIKYYKGLGTST+KEGKEYF+ + +H+K F+WA+ QDG
Sbjct: 579  AFYTMPEYEAWRRSLGATSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFVWADNQDG 638

Query: 2523 DAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIPSV 2344
            ++IELAFSKKKIEARKNWLRQFE GT+LD KEK I Y++FVNKELILFS ADLQRSIPS+
Sbjct: 639  ESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPSM 698

Query: 2343 VDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFVGS 2164
            +DGLKPGQRKILFCAFKRNFVKEAKV+QFSGYVSEHSAYHHGEQSL STI+GMAQD+VGS
Sbjct: 699  LDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVGS 758

Query: 2163 NNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSIEP 1984
            NN+NL QPNGQFGTRN GGKD AS+RYIYT LSPI RFLFPK        LNEDGQSIEP
Sbjct: 759  NNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKDDDTILDYLNEDGQSIEP 818

Query: 1983 AWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFKGT 1804
             WYVP+IP VLVNGSEGIGTGWSSY+PNYNPRD++ANVRRLLN E M+PMDPWY+GFKG 
Sbjct: 819  TWYVPVIPTVLVNGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDELMEPMDPWYKGFKGK 878

Query: 1803 IEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEPFI 1624
            IEK+A KETG TYT++GIIEEV  TTLRI+ELP+R WT DY QFL+ M   TDK K+ FI
Sbjct: 879  IEKTATKETGATYTVTGIIEEVSETTLRISELPVRRWTEDYKQFLESMTVSTDKAKDSFI 938

Query: 1623 QDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKYDS 1444
            ++ RAY D+ +V FEVI+SE+NL  A QEGL KKFKL TTISTSNMHLFDS G IKKYD+
Sbjct: 939  KEVRAYGDENSVCFEVIMSEDNLLLAQQEGLLKKFKLTTTISTSNMHLFDSKGKIKKYDA 998

Query: 1443 PEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAELF 1264
            PE+ILE+F+H+RL++YEKRKK               KV+FIL VV GEIIVNNRKRAEL 
Sbjct: 999  PEEILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKGEIIVNNRKRAELL 1058

Query: 1263 HELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIGTL 1084
             EL  KGFTPFPKK K ++A +A +T           E  + GV+ASDY+YLLSM+IGTL
Sbjct: 1059 LELKNKGFTPFPKK-KPVEAVVADSTDDADDSEESPEESSR-GVRASDYDYLLSMAIGTL 1116

Query: 1083 TMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQELR 904
            T+EKVQELCA++D+   E+E++++ +PK LWM+DLD L+KQLDEQD+ D++ +  +++L+
Sbjct: 1117 TLEKVQELCADRDKLNAEVEDMRNATPKHLWMKDLDVLDKQLDEQDKIDIQTEEAREKLK 1176

Query: 903  RKINTGAAVSRKAGPK-KPRKNN---ATKGSXXXXXXXXXXXXGNVLEMGKPKPRGGQKK 736
            +K+   A    KA PK KPRK N    +                NV E+ KPK RG  + 
Sbjct: 1177 KKVMNAAG---KAAPKPKPRKTNKKAESTAESMDVSFGSTAETANVSEVVKPKGRG--RP 1231

Query: 735  AAAKTSVVE-SDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVVTKKQPGKRAAAR 559
            A AK  VVE  ++EDE++ LKDRLAAYNL+SSPD++ V   E+P+     K P KRAAA+
Sbjct: 1232 AKAKPIVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEVPK--AQTKAPAKRAAAQ 1289

Query: 558  N--TKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRKPRNATAKDT 385
                 ST  +S       DGE    I     D++F+   A  GKK G GRKP  A A   
Sbjct: 1290 KKALPSTPDVS-------DGEDAIEI----DDDEFEPAAAVGGKKKG-GRKPAAAKAAAA 1337

Query: 384  TTANPRKRGGTQGKTVLSQKLITDVLKSVKNA--SPEKKVRKMRASPFNKKSGSVLGR-- 217
                 +K         + Q+LIT VLK  ++A  SP++KVRKMRASPFNKKSG+V+G+  
Sbjct: 1338 PKPPGKKAPANNQSQSVGQRLITQVLKPAEDAGVSPDRKVRKMRASPFNKKSGAVMGKNT 1397

Query: 216  --AGGSAIESEDSAGSLSS-GNLEAEMNGVRLT-RNMPKRENRTKVTYVESGS 70
              +  S+ ESE+ +  + S G+L+ E++ V +  +  P+R  +   TYV S S
Sbjct: 1398 SSSSTSSHESEEVSPLIPSLGSLDEEVSEVVVAPKARPQRATKKTTTYVISDS 1450


>ref|XP_008231457.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Prunus mume]
          Length = 1471

 Score = 1275 bits (3298), Expect = 0.0
 Identities = 671/1079 (62%), Positives = 796/1079 (73%), Gaps = 19/1079 (1%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSGIV++LLSWA+FKQNK+LKKTDGTK +++  I KL+DAN AGG+NSEKCTLILTEGDS
Sbjct: 403  KSGIVDSLLSWANFKQNKDLKKTDGTKTERVHNINKLEDANLAGGKNSEKCTLILTEGDS 462

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG++ VGRDHYGVFPLRGKLLNVREA+  Q+++N EI+NIK+ILGLQ  KEY S
Sbjct: 463  AKALAMAGLAVVGRDHYGVFPLRGKLLNVREASATQVRDNEEIKNIKRILGLQQDKEYTS 522

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            +K LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKI  F+VEFITPIVKA+HK+GK
Sbjct: 523  LKSLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGK 582

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
             L+FY+MPEYEAWKESL GNASGWSIKYYKGLGTST+KEG++YF+ +  HKK FIW +E+
Sbjct: 583  SLAFYSMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGRDYFQNLAMHKKDFIWIDER 642

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DG+AIELAFSKKKIE RKNWLRQFE   +LD KEK IKYSDFV+KELI FS ADLQRSIP
Sbjct: 643  DGEAIELAFSKKKIEERKNWLRQFEPSVHLDQKEKLIKYSDFVHKELIQFSMADLQRSIP 702

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S+VDGLKPGQRKILFC+FKRNFVKEAKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+V
Sbjct: 703  SMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYV 762

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINL QPNGQFGTRN GGKD ASARYIYT LSPITRFLFPK        LNEDGQSI
Sbjct: 763  GSNNINLLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYLNEDGQSI 822

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WYVPIIP VLVNGSEGIGTGWSSYIPNYNPRD++ANVRRLLN E M PMDPWYRGF 
Sbjct: 823  EPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMDPWYRGFA 882

Query: 1809 GTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEP 1630
            GTIEK+  KE+GV+YT+ G+IEE + TT+RI+ELPIR WT DY +FL+ +  G DK K+P
Sbjct: 883  GTIEKTV-KESGVSYTVCGVIEEGNETTVRISELPIRRWTQDYKEFLESISQGNDKAKDP 941

Query: 1629 FIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKY 1450
            FI+    ++D + V   V L EENL AA QEGL KKFKL T+ISTSNMHLFD  GVIKKY
Sbjct: 942  FIEGFTQHSDHSTVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDPKGVIKKY 1001

Query: 1449 DSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAE 1270
            D+PEQILE+FFHLRL+FYEKRKKV              KVRFILAVV+GEIIV+NR+RA+
Sbjct: 1002 DTPEQILEEFFHLRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIVSNRRRAD 1061

Query: 1269 LFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIG 1090
            LF EL QKGFTPFPKKTK  +  +AGA                 G + SDYEYL+SM+IG
Sbjct: 1062 LFLELQQKGFTPFPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIG 1121

Query: 1089 TLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQE 910
            TLT+E+VQ LCA++D+  +E+ EL++++P++LW++DLDALE +L E ++ +  A+  K++
Sbjct: 1122 TLTIERVQALCADRDKVNNEVAELRNSTPRSLWLKDLDALEMELGELEKSEALAEEAKKK 1181

Query: 909  LRRKI-NTGAAVSRKAGPKKPRKNNATKGSXXXXXXXXXXXXGNVLEMGK---------- 763
             R ++ N  AA   K  PK PRKNN    +              V EM K          
Sbjct: 1182 SRNQVKNAPAAKVSKPAPKNPRKNNKKANNAEAAAESRETSSSFVFEMEKAPEIVKRKVG 1241

Query: 762  --PKPRGGQKKAAAKTSVVESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVVTK 589
               K     KK  AK++VV SDD+DE++ELKDRLAAYNLDSSP+ ++ +  E+PQE V +
Sbjct: 1242 AVAKKAPAGKKQQAKSAVVLSDDDDEVLELKDRLAAYNLDSSPENSAGKETEVPQEPVQR 1301

Query: 588  KQPGKRAAARNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRKP 409
            K+P KRA                       MQ  I+D  D + ++  AP   K G GRK 
Sbjct: 1302 KEPSKRA-----------------------MQ--IDDDEDFEVEIAAAPAAGKKG-GRKA 1335

Query: 408  RNATAKDTTTANPRKRGG----TQGKTVLSQKLITDVLKSVKNA--SPEKKVRKMRASPF 247
               T      A  +KRG     +Q  +   QKL+TD+LK  + +  SPE KVRKMRASPF
Sbjct: 1336 AGTTKASKPPAAAKKRGAANKQSQASSSSGQKLLTDMLKPAETSGISPEPKVRKMRASPF 1395

Query: 246  NKKSGSVLGRAGGSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRTKVTYVESGS 70
            NKKSGSV+GR     +E  +S   + + + E   +     R  P+R NR +  YV S S
Sbjct: 1396 NKKSGSVMGRE-SLEVEMAESEEKVDTPSTEERSDAPVAARARPQRANRRQTRYVLSDS 1453


>ref|XP_008231458.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Prunus mume]
          Length = 1470

 Score = 1272 bits (3292), Expect = 0.0
 Identities = 671/1080 (62%), Positives = 798/1080 (73%), Gaps = 20/1080 (1%)
 Frame = -3

Query: 3249 KSGIVENLLSWADFKQNKELKKTDGTKKQKITGIPKLDDANDAGGRNSEKCTLILTEGDS 3070
            KSGIV++LLSWA+FKQNK+LKKTDGTK +++  I KL+DAN AGG+NSEKCTLILTEGDS
Sbjct: 403  KSGIVDSLLSWANFKQNKDLKKTDGTKTERVHNINKLEDANLAGGKNSEKCTLILTEGDS 462

Query: 3069 AKALAMAGVSEVGRDHYGVFPLRGKLLNVREATVQQIKNNAEIQNIKQILGLQHGKEYDS 2890
            AKALAMAG++ VGRDHYGVFPLRGKLLNVREA+  Q+++N EI+NIK+ILGLQ  KEY S
Sbjct: 463  AKALAMAGLAVVGRDHYGVFPLRGKLLNVREASATQVRDNEEIKNIKRILGLQQDKEYTS 522

Query: 2889 VKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIRGFMVEFITPIVKASHKSGK 2710
            +K LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKI  F+VEFITPIVKA+HK+GK
Sbjct: 523  LKSLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGK 582

Query: 2709 VLSFYTMPEYEAWKESLSGNASGWSIKYYKGLGTSTAKEGKEYFRAIDQHKKSFIWANEQ 2530
             L+FY+MPEYEAWKESL GNASGWSIKYYKGLGTST+KEG++YF+ +  HKK FIW +E+
Sbjct: 583  SLAFYSMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGRDYFQNLAMHKKDFIWIDER 642

Query: 2529 DGDAIELAFSKKKIEARKNWLRQFEHGTYLDHKEKEIKYSDFVNKELILFSRADLQRSIP 2350
            DG+AIELAFSKKKIE RKNWLRQFE   +LD KEK IKYSDFV+KELI FS ADLQRSIP
Sbjct: 643  DGEAIELAFSKKKIEERKNWLRQFEPSVHLDQKEKLIKYSDFVHKELIQFSMADLQRSIP 702

Query: 2349 SVVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLGSTIVGMAQDFV 2170
            S+VDGLKPGQRKILFC+FKRNFVKEAKVAQFSGYVSEHSAYHHGEQSL STI+GMAQD+V
Sbjct: 703  SMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYV 762

Query: 2169 GSNNINLFQPNGQFGTRNKGGKDCASARYIYTCLSPITRFLFPKXXXXXXXXLNEDGQSI 1990
            GSNNINL QPNGQFGTRN GGKD ASARYIYT LSPITRFLFPK        LNEDGQSI
Sbjct: 763  GSNNINLLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYLNEDGQSI 822

Query: 1989 EPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDVIANVRRLLNSEPMQPMDPWYRGFK 1810
            EP WYVPIIP VLVNGSEGIGTGWSSYIPNYNPRD++ANVRRLLN E M PMDPWYRGF 
Sbjct: 823  EPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEAMVPMDPWYRGFA 882

Query: 1809 GTIEKSAEKETGVTYTISGIIEEVDSTTLRITELPIRCWTTDYNQFLDDMMNGTDKIKEP 1630
            GTIEK+  KE+GV+YT+ G+IEE + TT+RI+ELPIR WT DY +FL+ +  G DK K+P
Sbjct: 883  GTIEKTV-KESGVSYTVCGVIEEGNETTVRISELPIRRWTQDYKEFLESISQGNDKAKDP 941

Query: 1629 FIQDKRAYNDDTAVHFEVILSEENLKAAIQEGLEKKFKLMTTISTSNMHLFDSNGVIKKY 1450
            FI+    ++D + V   V L EENL AA QEGL KKFKL T+ISTSNMHLFD  GVIKKY
Sbjct: 942  FIEGFTQHSDHSTVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDPKGVIKKY 1001

Query: 1449 DSPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXKVRFILAVVHGEIIVNNRKRAE 1270
            D+PEQILE+FFHLRL+FYEKRKKV              KVRFILAVV+GEIIV+NR+RA+
Sbjct: 1002 DTPEQILEEFFHLRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIVSNRRRAD 1061

Query: 1269 LFHELHQKGFTPFPKKTKGIDAAIAGATVXXXXXXXXXXEMVKGGVKASDYEYLLSMSIG 1090
            LF EL QKGFTPFPKKTK  +  +AGA                 G + SDYEYL+SM+IG
Sbjct: 1062 LFLELQQKGFTPFPKKTKAQEPEVAGAIEDTEETEENSESASGNGARISDYEYLISMAIG 1121

Query: 1089 TLTMEKVQELCAEKDRQEHELEELKSTSPKTLWMRDLDALEKQLDEQDRKDVEADRVKQE 910
            TLT+E+VQ LCA++D+  +E+ EL++++P++LW++DLDALE +L E ++ +  A+  K++
Sbjct: 1122 TLTIERVQALCADRDKVNNEVAELRNSTPRSLWLKDLDALEMELGELEKSEALAEEAKKK 1181

Query: 909  LRRKI-NTGAAVSRKAGPKKPRKNNATKGSXXXXXXXXXXXXGNVLEMGK---------- 763
             R ++ N  AA   K  PK PRKNN    +              V EM K          
Sbjct: 1182 SRNQVKNAPAAKVSKPAPKNPRKNNKKANNAEAAAESRETSSSFVFEMEKAPEIVKRKVG 1241

Query: 762  ---PKPRGGQKKAAAKTSVVESDDEDELIELKDRLAAYNLDSSPDQASVETEELPQEVVT 592
                K   G+K+  AK++VV SDD+DE++ELKDRLAAYNLDSSP+ ++ +  E+PQE V 
Sbjct: 1242 AVAKKAPAGKKQ--AKSAVVLSDDDDEVLELKDRLAAYNLDSSPENSAGKETEVPQEPVQ 1299

Query: 591  KKQPGKRAAARNTKSTLRISXXXXXXXDGERMQTIIEDGSDEDFQVMEAPKGKKTGAGRK 412
            +K+P KRA                       MQ  I+D  D + ++  AP   K G GRK
Sbjct: 1300 RKEPSKRA-----------------------MQ--IDDDEDFEVEIAAAPAAGKKG-GRK 1333

Query: 411  PRNATAKDTTTANPRKRGG----TQGKTVLSQKLITDVLKSVKNA--SPEKKVRKMRASP 250
                T      A  +KRG     +Q  +   QKL+TD+LK  + +  SPE KVRKMRASP
Sbjct: 1334 AAGTTKASKPPAAAKKRGAANKQSQASSSSGQKLLTDMLKPAETSGISPEPKVRKMRASP 1393

Query: 249  FNKKSGSVLGRAGGSAIESEDSAGSLSSGNLEAEMNGVRLTRNMPKRENRTKVTYVESGS 70
            FNKKSGSV+GR     +E  +S   + + + E   +     R  P+R NR +  YV S S
Sbjct: 1394 FNKKSGSVMGRE-SLEVEMAESEEKVDTPSTEERSDAPVAARARPQRANRRQTRYVLSDS 1452