BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Alisma22_contig00004295
         (3476 letters)

Database: ./nr 
           115,041,592 sequences; 42,171,959,267 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_010928876.1 PREDICTED: DNA topoisomerase 1 alpha [Elaeis guin...  1006   0.0  
JAT43915.1 DNA topoisomerase 1, partial [Anthurium amnicola] JAT...  1003   0.0  
XP_008782916.2 PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase...  1003   0.0  
XP_010913963.1 PREDICTED: DNA topoisomerase 1 alpha-like isoform...   990   0.0  
XP_009398771.1 PREDICTED: DNA topoisomerase 1 [Musa acuminata su...   988   0.0  
XP_020110486.1 DNA topoisomerase 1 alpha-like isoform X1 [Ananas...   980   0.0  
XP_010252639.1 PREDICTED: DNA topoisomerase 1 alpha-like [Nelumb...   980   0.0  
XP_008798752.1 PREDICTED: DNA topoisomerase 1-like [Phoenix dact...   977   0.0  
XP_009407901.1 PREDICTED: DNA topoisomerase 1-like isoform X2 [M...   976   0.0  
XP_010266803.1 PREDICTED: DNA topoisomerase 1 alpha-like [Nelumb...   966   0.0  
XP_009411876.1 PREDICTED: DNA topoisomerase 1 [Musa acuminata su...   953   0.0  
OAY66604.1 DNA topoisomerase 1 [Ananas comosus]                       944   0.0  
XP_020111558.1 DNA topoisomerase 1 beta-like isoform X1 [Ananas ...   942   0.0  
KMZ57043.1 DNA topoisomerase 1 [Zostera marina]                       938   0.0  
XP_002265386.1 PREDICTED: DNA topoisomerase 1 alpha isoform X1 [...   937   0.0  
XP_006659124.1 PREDICTED: DNA topoisomerase 1-like [Oryza brachy...   931   0.0  
ONK79065.1 uncharacterized protein A4U43_C01F2540 [Asparagus off...   929   0.0  
NP_001157806.2 topoisomerase I [Zea mays] AQK50787.1 DNA topoiso...   929   0.0  
ACS44671.1 DNA topoisomerase I [Zea mays]                             928   0.0  
XP_016720339.1 PREDICTED: DNA topoisomerase 1-like [Gossypium hi...   928   0.0  

>XP_010928876.1 PREDICTED: DNA topoisomerase 1 alpha [Elaeis guineensis]
          Length = 956

 Score = 1006 bits (2602), Expect = 0.0
 Identities = 554/960 (57%), Positives = 627/960 (65%), Gaps = 43/960 (4%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRRNXXXXXXXXXXXXXXXXXATPNPSLVKCPASQV 3073
            MAVHGCV Q I DN        +  R N                    + SL K  + + 
Sbjct: 1    MAVHGCVKQVIYDNGDDDDGPTVFKRPNSASKQSQLNSALKKSVSQRCDSSLGKLTSEKS 60

Query: 3072 SPNCENTYSRRNKVVS-VATSFKPSQVDLASSSRKSEGVSNQQKVSMNKPSSKTAEL--- 2905
            + N  N+  ++NK+ S V    + S+  +A S+ +       + +   KP+S + E    
Sbjct: 61   AMNHGNSNFQKNKITSTVKAPSEKSKSIIAGSNSRIALPDRSKHLPEKKPTSNSRETMHL 120

Query: 2904 ----------EDSDDEKPLSFRLAGTPLGINKESRTPLMKI------------------- 2812
                      +DSDD+KPLS RL    +   K +     K+                   
Sbjct: 121  DNICADAESSDDSDDDKPLSHRLNAASMVFQKNNSMHPEKVVNHSSEHKLATSSKDKMDL 180

Query: 2811 -----KPEDATSDDSDDEKPLSFRIPASGSGASQNSLNLKKKLTXXXXXXXXXXXXXXXX 2647
                 K ED  SDDSDD+KPLS +   S S   +NS    KK+                 
Sbjct: 181  DKPCRKRED--SDDSDDDKPLSSKF--SSSVVEKNSSLHSKKVLESPRHASPSAQKVQES 236

Query: 2646 XXXXXXXXXXXXXXXSLGATKNE----SPDSDDDDKPLAARFQQNGYSKNGSQISRHLLS 2479
                                K+     +  SDDD+KPLA + + NG  K G+        
Sbjct: 237  TKEDSDDSEDDKPLLFRFQPKSSGGASTKISDDDEKPLAFKVKPNGSIKKGTSNELRFPK 296

Query: 2478 GSGKRPSTSADKSALAANKKPKFSEGISQNKVKPEH-SXXXXXXXXDYVPISQRLXXXXX 2302
            G+ KRP    +     + KK K S      KVK E           D +PISQR+     
Sbjct: 297  GANKRPLGDTNNPIDYSIKKAKVSGSSYHEKVKQEVVEKKTDTDDNDRIPISQRIKKSGS 356

Query: 2301 XXXXXXXXXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVI 2122
                      +                             VPPGSG GQKWTTLEH+G+I
Sbjct: 357  SDSKSSTNKVMKKITGSLLKKDSKKMKKALKNSKFSKSLKVPPGSGGGQKWTTLEHNGLI 416

Query: 2121 FPPAYKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGE 1942
            FPP Y PHGVKMLY+G+PV+LTPEQEEVATMFAVMKDTDYA K  FI NFWNDWK ILG+
Sbjct: 417  FPPTYVPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPKFIENFWNDWKRILGK 476

Query: 1941 NHVIKDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKV 1762
            NHVIK F  CDFTPIYEWH +EKEKKKQMS                KYMWA+VDGVKEKV
Sbjct: 477  NHVIKKFELCDFTPIYEWHQREKEKKKQMSAEEKKALKEEKMKKEEKYMWAVVDGVKEKV 536

Query: 1761 GNFRVEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNT 1582
            GNFRVEPP LFRGRGEHPKMGKLKKR+ P DITINIGKG PIPECP+PGERWKE+KHDNT
Sbjct: 537  GNFRVEPPALFRGRGEHPKMGKLKKRVRPSDITINIGKGAPIPECPVPGERWKEVKHDNT 596

Query: 1581 VTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSK 1402
            VTWLAFWNDPINPKE KYVFLAASSSLKGQSDKEKYEKAR LKDYI  IRANYT+DFTSK
Sbjct: 597  VTWLAFWNDPINPKECKYVFLAASSSLKGQSDKEKYEKARLLKDYIDNIRANYTRDFTSK 656

Query: 1401 DESRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDS 1222
            D ++RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV LVPPN++QFDFLGKDS
Sbjct: 657  DATKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVVLVPPNKLQFDFLGKDS 716

Query: 1221 IRYFNTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAK 1042
            IRYFNTV VEP VYKAIGEF            + DDLFD LDTSKLN HLKELMPGLTAK
Sbjct: 717  IRYFNTVEVEPPVYKAIGEFRTARKSDGSKKGDGDDLFDLLDTSKLNAHLKELMPGLTAK 776

Query: 1041 VFRTYNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLN 862
            VFRTYNASITLD +LNK+T+DGT+ EKIAVYQ ANKEVAIICNHQRSVSK+HDAQMSRLN
Sbjct: 777  VFRTYNASITLDDILNKKTKDGTLPEKIAVYQHANKEVAIICNHQRSVSKSHDAQMSRLN 836

Query: 861  EKIEELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELD 682
            EKI +LKAQREELK DL RARKGKPPLK+ EGKPKRN++P+ALEKK++Q+DAKIEKMELD
Sbjct: 837  EKIADLKAQREELKVDLSRARKGKPPLKNGEGKPKRNLSPEALEKKIAQMDAKIEKMELD 896

Query: 681  KKIKDDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            KK+K+DLKTVALGTSKINYLDPRI+VAWCKR+EVPIEKIFNKSLLAKFTWAMD DPSFRF
Sbjct: 897  KKVKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 956


>JAT43915.1 DNA topoisomerase 1, partial [Anthurium amnicola] JAT66129.1 DNA
            topoisomerase 1, partial [Anthurium amnicola]
          Length = 929

 Score = 1003 bits (2594), Expect = 0.0
 Identities = 554/929 (59%), Positives = 634/929 (68%), Gaps = 12/929 (1%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRRNXXXXXXXXXXXXXXXXXATPNPSLVKCPAS-Q 3076
            MAV+ C S+ + DN     D+PI+F+RN                 +     L   P   Q
Sbjct: 22   MAVYDCSSKNLCDN-GDEDDQPIVFKRNNATSKQNQLHSALKKPSSQKTDRLSGKPGPVQ 80

Query: 3075 VSPNCENTYSRRNKVVSVATSFKPSQVDLASSSRKSEGVSNQQKVS--MNKPSSKTAELE 2902
             +P+   + SR+ +V S + +         S++R +  V  ++  S   N  +  T + +
Sbjct: 81   SAPSGGGSSSRKGEVPSASKAVAGRAGGPISNNRSALPVQLKRSSSNGTNNVNGDTPDND 140

Query: 2901 DSDDEKPLSFRLAGTPLGINKESRTPLMKIKPEDATSDDSDDEKPLSFRIP-ASGSGASQ 2725
            DSDD+KPLSFRL+ T     K S   L K +     SDDSDD KPLSFR+  AS  G   
Sbjct: 141  DSDDDKPLSFRLSATSATPQKSSS--LTKSQGGGENSDDSDDNKPLSFRVSGASLGGQKS 198

Query: 2724 NSLNLKKK-----LTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGATKNESPDSDD 2560
            N+LN +K      +                                 +    + +PD  D
Sbjct: 199  NTLNSRKVQSSSVINPSSSQKSKPEIKKYSDDSEDEKPLFSRFQSKPVLGKSSRTPDDSD 258

Query: 2559 DDKPLAARFQQNGYSKNGSQISRHLLSGSGKRPSTSADKSALAANKKPKFSEGISQNKVK 2380
            D+KPLA+RF QNG               S KRP  S +KS   +NKK K  +  +  KVK
Sbjct: 259  DEKPLASRFHQNG---------------SNKRPFNSVNKSGEPSNKKAKLLDTTAA-KVK 302

Query: 2379 PEHSXXXXXXXXD--YVPISQRLXXXXXXXXXXXXXXKVLNKVVXXXXXXXXXXXXXXXX 2206
             E +        D  ++PI+QR                V+ KV                 
Sbjct: 303  CEAAVKKEVNADDDDHIPIAQRTKKLASNEKQSSTKK-VIKKVTTTSFKKKKMTKKMMKN 361

Query: 2205 XXXXXXSTVPPGSGEGQKWTTLEHSGVIFPPAYKPHGVKMLYDGKPVNLTPEQEEVATMF 2026
                    VPPGSGEGQKWTTL HSGVIFPP YKPHG+KMLY+ KPVNLTPEQEEVATMF
Sbjct: 362  SKYSKSFKVPPGSGEGQKWTTLAHSGVIFPPPYKPHGIKMLYNRKPVNLTPEQEEVATMF 421

Query: 2025 AVMKDTDYAAKKTFITNFWNDWKEILGENHVIKDFAQCDFTPIYEWHLKEKEKKKQMSTX 1846
            AVMKDT+YA KK FI NF  DW+ ILG NH+IK F  CDFTPIYEWHL+EKEKKKQMST 
Sbjct: 422  AVMKDTEYATKKIFIDNFMKDWRAILGPNHIIKQFELCDFTPIYEWHLEEKEKKKQMSTE 481

Query: 1845 XXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPHDI 1666
                          KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DI
Sbjct: 482  EKKALKEEKLKQEEKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDI 541

Query: 1665 TINIGKGVPIPECPIPGERWKEIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSD 1486
            TINIGK  PIPECPI GERWKEI+HDNTVTWLA+W DPIN +EFKYVFLAASS+LKGQSD
Sbjct: 542  TINIGKDAPIPECPIAGERWKEIRHDNTVTWLAYWIDPINQREFKYVFLAASSTLKGQSD 601

Query: 1485 KEKYEKARKLKDYIQTIRANYTKDFTSKDESRRQIAVATYLIDKLALRAGNEKDD-DEAD 1309
            KEKYEKAR LKDYIQ IRA YTKDFTSKD+++RQIAVATYLIDKLALRAGNEK++ +EAD
Sbjct: 602  KEKYEKARMLKDYIQNIRAKYTKDFTSKDDTKRQIAVATYLIDKLALRAGNEKEEGEEAD 661

Query: 1308 TVGCCTLKVENVALVPPNQIQFDFLGKDSIRYFNTVVVEPAVYKAIGEFXXXXXXXXXXX 1129
            TVGCCTLKVENVALVPPN +QFDFLGKDSIRYFNTV VEPAVYKAIGEF           
Sbjct: 662  TVGCCTLKVENVALVPPNNLQFDFLGKDSIRYFNTVEVEPAVYKAIGEFRLKSFNGKKKH 721

Query: 1128 XNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRTYNASITLDQMLNKETRDGTVQEKIAVY 949
              +D LF  LDTSKLN HLKELMPGLTAKVFRTYNASITLD+MLNKET+DGTV EK+AVY
Sbjct: 722  D-TDLLFHMLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNKETKDGTVPEKLAVY 780

Query: 948  QTANKEVAIICNHQRSVSKTHDAQMSRLNEKIEELKAQREELKEDLHRARKGKPPLKDAE 769
            Q ANKEVAIICNHQRSVSK+HDAQM+RLN+K+ ELK Q EELK DL RARKGKPPLKDAE
Sbjct: 781  QQANKEVAIICNHQRSVSKSHDAQMTRLNDKLAELKTQHEELKVDLSRARKGKPPLKDAE 840

Query: 768  GKPKRNMAPDALEKKLSQVDAKIEKMELDKKIKDDLKTVALGTSKINYLDPRITVAWCKR 589
            GK K+N++P+ALEKKL+Q+D KIEK+ELDKK+K+DLKTVALGTSKINYLDPRI+VAWCKR
Sbjct: 841  GKMKKNLSPEALEKKLAQLDVKIEKIELDKKLKEDLKTVALGTSKINYLDPRISVAWCKR 900

Query: 588  YEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            +EVPIEKIFNKSLLAKF WAMDADPSFRF
Sbjct: 901  HEVPIEKIFNKSLLAKFAWAMDADPSFRF 929


>XP_008782916.2 PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Phoenix
            dactylifera]
          Length = 950

 Score = 1003 bits (2592), Expect = 0.0
 Identities = 548/952 (57%), Positives = 625/952 (65%), Gaps = 35/952 (3%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRRNXXXXXXXXXXXXXXXXXATPNPSLVKCPASQV 3073
            MAVH C+ Q I D+        +  R N                    + SL K  + + 
Sbjct: 1    MAVHSCIKQVIYDDGDDDDGPAVFKRSNSASKQKQLNSASKKSTSQRCDSSLGKLRSEKS 60

Query: 3072 SPNCENTYSRRNKVVSV--ATSFKPSQVDLASSSRKSEGVSNQQKVSMNKPSSKTAELE- 2902
              N  N+  ++NK+ S   A S K   +   S+SR ++   +  +  +   S +TA L+ 
Sbjct: 61   VTNYGNSNFQKNKITSTVKAASEKSESMVAGSNSRIADQSKHFAEHKLASNSKETAHLDN 120

Query: 2901 ---------DSDDEKPLSFRLAGTP-----------------LGINKESRTPLMKIKPED 2800
                     DSDD+KPLS RL                     L  + + +  L K   + 
Sbjct: 121  ICADAESSDDSDDDKPLSHRLNAASMVFHRNNSMHADSSEHKLATSSKDKMDLDKPCNKS 180

Query: 2799 ATSDDSDDEKPLSFRIPASGSGASQNSLNLKK-----KLTXXXXXXXXXXXXXXXXXXXX 2635
              SDDSDD+KPLS +  +S      +S + KK     + T                    
Sbjct: 181  EDSDDSDDDKPLSSKFSSSVVVEKSSSSHAKKVFESPRHTSLSSQKLKERTKEDSDDSED 240

Query: 2634 XXXXXXXXXXXSLGATKNESPDSDDDDKPLAARFQQNGYSKNGSQISRHLLSGSGKRPST 2455
                       S G    +   SDDD+KPLA++ + NG  K G+        G+ KRP  
Sbjct: 241  DEPLLSRFQPKSAGGASTKI--SDDDEKPLASKVKPNGSVKKGTSNELRFSKGANKRPLG 298

Query: 2454 SADKSALAANKKPKFSEGISQNKVKPEH-SXXXXXXXXDYVPISQRLXXXXXXXXXXXXX 2278
              +    ++ KK K S+     KVK E           D++PI+QR+             
Sbjct: 299  DTNNRIDSSIKKAKVSDSSYHAKVKQEVVEKKPGTDDNDHIPIAQRIKKSGSSDNKSSTN 358

Query: 2277 XKVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIFPPAYKPH 2098
              +                             VPPGSG GQKWTTLEH+GVIFPP YKPH
Sbjct: 359  KVMKKITCSPFKKDSKKMKKAMKNSKFSKSLKVPPGSGGGQKWTTLEHNGVIFPPPYKPH 418

Query: 2097 GVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHVIKDFA 1918
            GV+MLY+G+PV+LTPEQEEVATMFAVMKDTDYA K  FI NFWNDWK+ILG+NHVIK F 
Sbjct: 419  GVRMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPKFIENFWNDWKQILGKNHVIKKFE 478

Query: 1917 QCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPP 1738
             CDFTPIYEWH ++KEK KQMS                KYMWA+VDGVKEKVGNFRVEPP
Sbjct: 479  LCDFTPIYEWHQRQKEKNKQMSAEEKKALKEDKLKQEEKYMWAVVDGVKEKVGNFRVEPP 538

Query: 1737 GLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTVTWLAFWN 1558
            GLFRGRGEHPKMGKLKKRI P DITINIGKG PIPECPIPGERWKE+KHDNTVTWLAFWN
Sbjct: 539  GLFRGRGEHPKMGKLKKRIRPSDITINIGKGAPIPECPIPGERWKEVKHDNTVTWLAFWN 598

Query: 1557 DPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDESRRQIA 1378
            DPIN KEFKYVFLAASSSLKGQSDKEKYEKAR LKDYI  IRANYT+DFTSKD ++RQIA
Sbjct: 599  DPINLKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTRDFTSKDAAKRQIA 658

Query: 1377 VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRYFNTVV 1198
            VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV LVPPN++QFDFLGKDSIRYFNTV 
Sbjct: 659  VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVVLVPPNKLQFDFLGKDSIRYFNTVE 718

Query: 1197 VEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRTYNAS 1018
            VEP VYKAIGEF              DDLFD LDTSKLN HLKELMPGLTAKVFRTYNAS
Sbjct: 719  VEPPVYKAIGEFRTARKSHGSKKSGGDDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNAS 778

Query: 1017 ITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKIEELKA 838
            ITLD +LN+ET+DGT+ EKIAVYQ ANKEVAIICNHQRSVSK+HDAQMSRLN KI ++KA
Sbjct: 779  ITLDDILNRETKDGTLPEKIAVYQHANKEVAIICNHQRSVSKSHDAQMSRLNGKIADIKA 838

Query: 837  QREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKIKDDLK 658
            QREELK DL RARKGKPPLKD EGKPKR M+P  LEKK++Q+DAKIEKMELD KIK+DLK
Sbjct: 839  QREELKVDLSRARKGKPPLKDGEGKPKRIMSPQVLEKKVAQIDAKIEKMELDXKIKEDLK 898

Query: 657  TVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            TVALGTSKINYLDPRI+VAWCKR+EVPIEKIFNKSLLAKF WAMD DP+FRF
Sbjct: 899  TVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPTFRF 950


>XP_010913963.1 PREDICTED: DNA topoisomerase 1 alpha-like isoform X1 [Elaeis
            guineensis] XP_019704056.1 PREDICTED: DNA topoisomerase 1
            alpha-like isoform X1 [Elaeis guineensis]
          Length = 951

 Score =  990 bits (2560), Expect = 0.0
 Identities = 556/962 (57%), Positives = 638/962 (66%), Gaps = 45/962 (4%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRR-NXXXXXXXXXXXXXXXXXATPNPSLVKCPASQ 3076
            MAV G + Q   D+     D P IF+R N                      SL K  + +
Sbjct: 1    MAVPGSIKQVPYDDGDDDDDGPTIFKRPNSASRQSQLNSGSKKPASQKRINSLGKLASDE 60

Query: 3075 VSPNCENTYSRRNKVVSV--ATSFKPSQVDLASSSR-----KSEGVSNQQKVSMNKPSSK 2917
             +PN  N+  ++NK+     A S K   +   S+SR     +S+  + Q+  S N  ++ 
Sbjct: 61   GTPNYGNSNFQKNKMTCTVKAPSEKSKSIIAGSNSRTSFPDQSKHFAEQKLTSNNNETTH 120

Query: 2916 TAEL-------EDSDDEKPLSFRLAGTPLGINKESRTPLMKI------------------ 2812
                       +DSDD+KPLS RL    + + K +   + K+                  
Sbjct: 121  LDNFGADAENSDDSDDDKPLSHRLNAVSMAVQKNNSVHMEKVANHSSEHKLATSCKGKMN 180

Query: 2811 ------KPEDATSDDSDDEKPLSFRIPASGSGASQNSLNLKKKLTXXXXXXXXXXXXXXX 2650
                  K ED  SDDSDD+K LS +  +S   A +NS +  K+                 
Sbjct: 181  LDKPCGKIED--SDDSDDDKTLSSKF-SSSVVAEKNSFSQAKRALESPRPTSLSSQKLKE 237

Query: 2649 XXXXXXXXXXXXXXXXSLGATKN----ESPDSDDDDKPLAARFQQNGYSKNGSQISRHLL 2482
                            S   TK+     +  SD   KPLA++F+ NG  K   + S  L 
Sbjct: 238  IAKEDSDDSEDDKPLLSRFQTKSTGGASTKLSDSVGKPLASKFKPNGSIKK--ETSNELS 295

Query: 2481 -SGSGKRPSTSADKSALAANKKPKFSEGISQNKVKPEH-SXXXXXXXXDYVPISQRLXXX 2308
              G+ KRP    +K   ++ KK K S+     K+K E           D++PI+QR+   
Sbjct: 296  PKGANKRPLGDTNKFIYSSIKKAKVSDSSRPIKIKQEVVKKETNTDDYDHIPIAQRIKKS 355

Query: 2307 XXXXXXXXXXXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSG 2128
                        +                             VPPGSG GQKWTTLEH+G
Sbjct: 356  GSSDNKSSTNKVMKKITSSSFKKDGKKMKKAMKDSKFSKSLKVPPGSGGGQKWTTLEHNG 415

Query: 2127 VIFPPAYKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEIL 1948
            VIFPPAY+PHGVKMLY+G+PV+LTPEQEEVATMFAVMKDTDYA K  FI NFWNDWK+IL
Sbjct: 416  VIFPPAYQPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPKFIENFWNDWKQIL 475

Query: 1947 GENHVIKDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKE 1768
            G++HVIK F  CDFTPIYEWHL+EKEKKKQMS                KYMWAIVDGVKE
Sbjct: 476  GKSHVIKKFDLCDFTPIYEWHLREKEKKKQMSAEEKKALKEEKLKQEEKYMWAIVDGVKE 535

Query: 1767 KVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHD 1588
            KVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIGKG PIPECPIPGERWKE+KH+
Sbjct: 536  KVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKGAPIPECPIPGERWKEVKHE 595

Query: 1587 NTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFT 1408
            NTVTWLAFWNDPINPKEFKYVFLAASS+LKGQSDKEKYEKAR LKDYI  IRANYT+DFT
Sbjct: 596  NTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHNIRANYTRDFT 655

Query: 1407 SKDESRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGK 1228
            SKD ++RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV L+PPN++QFDFLGK
Sbjct: 656  SKDATKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVVLIPPNKLQFDFLGK 715

Query: 1227 DSIRYFNTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLT 1048
            DSIRYFNTV VE  VYKAIGEF            + DDLFD LDTSKLN HLKELMPGLT
Sbjct: 716  DSIRYFNTVEVELPVYKAIGEF------RTARKSDGDDLFDLLDTSKLNAHLKELMPGLT 769

Query: 1047 AKVFRTYNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSR 868
            AKVFRTYNASITLD +LNKET++GT+ EKIAVYQ ANKEVAIICNHQRSVSK+HDAQMSR
Sbjct: 770  AKVFRTYNASITLDDILNKETKEGTLPEKIAVYQHANKEVAIICNHQRSVSKSHDAQMSR 829

Query: 867  LNEKIEELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKME 688
            LNEKI +LK QREELK DL RARKGKPPLKD EGK KRN++ +ALEKK++Q+D+KIEKME
Sbjct: 830  LNEKIMDLKTQREELKVDLSRARKGKPPLKDREGKTKRNLSSEALEKKIAQIDSKIEKME 889

Query: 687  LDKKIKDDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSF 508
            LDKKIK+DLKTVALGTSKINYLDPRITVAWCKR+EVPIEKIFNKSLLAKFTWAMD DPSF
Sbjct: 890  LDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSF 949

Query: 507  RF 502
            RF
Sbjct: 950  RF 951


>XP_009398771.1 PREDICTED: DNA topoisomerase 1 [Musa acuminata subsp. malaccensis]
          Length = 948

 Score =  988 bits (2555), Expect = 0.0
 Identities = 550/957 (57%), Positives = 634/957 (66%), Gaps = 40/957 (4%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRR-NXXXXXXXXXXXXXXXXXATPNPSLVKCPASQ 3076
            M+VHGC++Q ++++     + PIIF+R N                      +LV   + Q
Sbjct: 1    MSVHGCINQ-VMNDSGEDDEGPIIFKRPNSSSKQSHLSSTSKKTTQKHDGSNLV---SGQ 56

Query: 3075 VSPNCENTYSRRNKVVSVATSF--KPSQVDLASSSRKSEGVSNQQKVS-------MNKPS 2923
            ++ N EN+  +  +V+  A +   KP     +S S +S+ +S  +  +        +  S
Sbjct: 57   IARNGENSRLQSAEVLPTAKTLNEKPISHSQSSVSVQSKHISYHKSTTNDVRPKYQDVSS 116

Query: 2922 SKTAELEDSDDEKPLSFRLAGTPLGINKESRTPLMK------------------------ 2815
             +  E +DSDD KPLS RL   P  + K++     K                        
Sbjct: 117  LEVRESDDSDDGKPLSHRLNSPPAAVQKKNTMGSEKTHMHSSDHKFVNKSTDKMNLDKPI 176

Query: 2814 IKPEDATSDDSDDEKPLSFRIPASG----SGASQNSLNLKKKLTXXXXXXXXXXXXXXXX 2647
            IK ED  SDDSDDEKPLS +  +S      G S        K T                
Sbjct: 177  IKRED--SDDSDDEKPLSLKFSSSTVVNKGGPSHAMKTQSAKPTLLPSLKINSDIKGCSD 234

Query: 2646 XXXXXXXXXXXXXXXSLGATKNESPDSDDDDKPLAARFQQNGYSKNGSQISRHLLSGSGK 2467
                           ++G++  +S  S  DDKPL+++ + NG SK           G  K
Sbjct: 235  DSEDEKPLLSRFQSKAIGSSSMKS--STSDDKPLSSKLKLNGSSKKEGNSENRSSGGGQK 292

Query: 2466 RPSTSADKSALAANKKPKFSEGISQNKVKPEHSXXXXXXXXD--YVPISQRLXXXXXXXX 2293
            RP    D +  ++ KK K SE  +  KVK E +        D  +V ISQR+        
Sbjct: 293  RPLGDPDPTGSSSVKKAKVSETSASVKVKHEVAVKKEIKADDTNHVSISQRIKKSVSSNS 352

Query: 2292 XXXXXXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIFPP 2113
                   V  K                          VPPGSG GQKWTTLEH+GVIFPP
Sbjct: 353  ASTSKN-VSQKNHSLFKKDIKKMKKKDKDSKFSKILKVPPGSGGGQKWTTLEHNGVIFPP 411

Query: 2112 AYKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHV 1933
             Y PHG+KMLY G+PV+LTPEQEEVATMFAVMKDT+YA K  FI NF NDW++ILG++HV
Sbjct: 412  PYNPHGIKMLYKGQPVDLTPEQEEVATMFAVMKDTEYATKNQFIENFMNDWRQILGKSHV 471

Query: 1932 IKDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNF 1753
            IK F  CDFTPIYEWHL+EKEKKKQMST               KYMWAIVDGVKEKVGNF
Sbjct: 472  IKKFELCDFTPIYEWHLREKEKKKQMSTEEKKALKEEKLKQEEKYMWAIVDGVKEKVGNF 531

Query: 1752 RVEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTVTW 1573
            RVEPPGLFRGRGEHPKMGKLKKRI P DITINIGK  PIPECPIPGERWKE+KHDNTVTW
Sbjct: 532  RVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKEAPIPECPIPGERWKEVKHDNTVTW 591

Query: 1572 LAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDES 1393
            LAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LK+YI  IRANYT+DFTSKD +
Sbjct: 592  LAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKNYIHNIRANYTRDFTSKDPT 651

Query: 1392 RRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRY 1213
            +RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV LVPPN ++FDFLGKDSIRY
Sbjct: 652  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPNMLKFDFLGKDSIRY 711

Query: 1212 FNTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFR 1033
             NTVVVE  VYKAIGEF              DDLFD LDTSKLN HLKELMPGLTAKVFR
Sbjct: 712  LNTVVVELPVYKAIGEFQTAKKSDGGRKSKGDDLFDLLDTSKLNAHLKELMPGLTAKVFR 771

Query: 1032 TYNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKI 853
            TYNASITLD +LNKET+DGT+ EKIAVYQ ANKEVAIICNHQRSVSK+H++QMS+LNEKI
Sbjct: 772  TYNASITLDDILNKETKDGTLPEKIAVYQHANKEVAIICNHQRSVSKSHESQMSKLNEKI 831

Query: 852  EELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKI 673
             +LK QREEL+ DL RARKGKPPLKD EGK K+N++P+ +EKKL+QVDAKIEKMELDKKI
Sbjct: 832  NDLKTQREELEMDLSRARKGKPPLKDREGKTKKNLSPEVIEKKLAQVDAKIEKMELDKKI 891

Query: 672  KDDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            K+DLKTVALGTSKINYLDPRI+VAWCKR+EVPIEKIFNKSLLAKF WAMD +P FRF
Sbjct: 892  KEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVEPDFRF 948


>XP_020110486.1 DNA topoisomerase 1 alpha-like isoform X1 [Ananas comosus] OAY76967.1
            DNA topoisomerase 1 [Ananas comosus]
          Length = 885

 Score =  980 bits (2534), Expect = 0.0
 Identities = 536/934 (57%), Positives = 617/934 (66%), Gaps = 17/934 (1%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRRNXXXXXXXXXXXXXXXXXATPNPSLVKCPASQV 3073
            MAV+GC+S    DN        I  R +                    N SL +  +++ 
Sbjct: 1    MAVNGCISPVPYDNDEDEDGPAIFKRPSSSKNGQINSSLKKPASQNHYNSSLGRTTSNKH 60

Query: 3072 SPNCENTYSRRNKVVSVATSFKPSQVDLASSSRKSEGVSNQQKVSMNKPSSKTAELEDSD 2893
            S N EN+ S++NK +S       +    +  SR S  VSN +   + +P S+    +DSD
Sbjct: 61   SSNGENSNSQKNKAISAVKISNQNPRSTSLVSRASVPVSNVKSTHLQRPHSEAENTDDSD 120

Query: 2892 DEKPLSFRLAGTPLGINKESRTPLMKIKPEDATSD---DSDDEKPLSFR-IPASGSGASQ 2725
            D+KPL++RL  +    +++S + L++    D+ S+   DSDD +PLS + +PA     S 
Sbjct: 121  DDKPLTYRL-NSASAASQKSNSMLVERAILDSKSEFSYDSDDNRPLSSKSLPAVTEKGS- 178

Query: 2724 NSLNLKKKLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGATKNESPDSDDDDKPL 2545
                                                          K E  D  +DDKPL
Sbjct: 179  ----------------------------------------------KKEYSDDSEDDKPL 192

Query: 2544 ----------AARFQQNGYSKNGSQISRHLLSGSGKRPSTSADKSALAANKKPKFSEGIS 2395
                      A++   N   K  S        G  KRP   ++ S   + KKPK     +
Sbjct: 193  LSRLPLKSTSASKVAPNASIKKESSSDLGFTKGLNKRPLGDSNSSIGPSIKKPKIFNSSA 252

Query: 2394 QNKVKPEHSXXXXXXXXDY---VPISQRLXXXXXXXXXXXXXXKVLNKVVXXXXXXXXXX 2224
              KVK E S        D    +P+SQRL               ++ K            
Sbjct: 253  SVKVKDEGSVKEELKTEDDDDDIPLSQRLKNSQSSERKPSSNK-IIKKPTSSFKKDWKKM 311

Query: 2223 XXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIFPPAYKPHGVKMLYDGKPVNLTPEQE 2044
                          VPPGSG G+KWTTLEH+GVIFPP Y PHGVKMLY+G+PV+LTPEQE
Sbjct: 312  KKSFKNSQFSKRLKVPPGSGGGKKWTTLEHNGVIFPPPYAPHGVKMLYNGQPVDLTPEQE 371

Query: 2043 EVATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHVIKDFAQCDFTPIYEWHLKEKEKK 1864
            EVATMFAVMKDTDYA K  FI NFWNDW++ILG+NHVIK F  CDFTPIYEWHL+EKEKK
Sbjct: 372  EVATMFAVMKDTDYATKPKFIENFWNDWRQILGKNHVIKKFELCDFTPIYEWHLREKEKK 431

Query: 1863 KQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 1684
            KQMS+               KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+R
Sbjct: 432  KQMSSEEKKALKEEKLKKEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRR 491

Query: 1683 IYPHDITINIGKGVPIPECPIPGERWKEIKHDNTVTWLAFWNDPINPKEFKYVFLAASSS 1504
            I P DITINIGK  PIPECPI GERWKEIKHDNTVTWLAFW DPIN +EFKYVFLAASSS
Sbjct: 492  IRPSDITINIGKDAPIPECPILGERWKEIKHDNTVTWLAFWPDPINSREFKYVFLAASSS 551

Query: 1503 LKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDESRRQIAVATYLIDKLALRAGNEKD 1324
            LKGQSDKEKYEKAR LKDYI TIR NYT+DFTS+D ++RQIAVATYLIDKLALRAGNEKD
Sbjct: 552  LKGQSDKEKYEKARLLKDYIHTIRENYTRDFTSRDATKRQIAVATYLIDKLALRAGNEKD 611

Query: 1323 DDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRYFNTVVVEPAVYKAIGEFXXXXXX 1144
            DDEADTVGCCTLKVENV  VPPN++QFDFLGKDSIRYFNTV VE  VYKAI EF      
Sbjct: 612  DDEADTVGCCTLKVENVVCVPPNKLQFDFLGKDSIRYFNTVEVELPVYKAIEEFRTAKKS 671

Query: 1143 XXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRTYNASITLDQMLNKETRDGTVQE 964
                    DDLFD LDTSKLN HLKELMPGLTAKVFRTYNASITLD +LNKET++GT+ E
Sbjct: 672  DGKRKSIGDDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDNILNKETKEGTLPE 731

Query: 963  KIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKIEELKAQREELKEDLHRARKGKPP 784
            KIAVYQ ANKEVAIICNHQRSVSK+H++QMS+LNEKI +LKA REELK DL RARKGKPP
Sbjct: 732  KIAVYQHANKEVAIICNHQRSVSKSHESQMSKLNEKINDLKALREELKVDLSRARKGKPP 791

Query: 783  LKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKIKDDLKTVALGTSKINYLDPRITV 604
            LKD EG PK+N++PDA+EKKLSQ + KIEKME+DKKIK+DLKTVALGTSKINYLDPRI+V
Sbjct: 792  LKDKEGTPKKNLSPDAIEKKLSQTEVKIEKMEIDKKIKEDLKTVALGTSKINYLDPRISV 851

Query: 603  AWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            AWCKR+EVPIEKIFNKSLLAKF WAMD DP +RF
Sbjct: 852  AWCKRHEVPIEKIFNKSLLAKFAWAMDVDPGYRF 885


>XP_010252639.1 PREDICTED: DNA topoisomerase 1 alpha-like [Nelumbo nucifera]
          Length = 883

 Score =  980 bits (2534), Expect = 0.0
 Identities = 538/927 (58%), Positives = 620/927 (66%), Gaps = 10/927 (1%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRRNXXXXXXXXXXXXXXXXXATPNP-SLVKCPASQ 3076
            MAV  C+  KI+D+     + P +F+RN                 +  N  S  K  +  
Sbjct: 1    MAVDACIKPKIIDD-DDDDEGPAVFKRNNTASRKNQVNSELKKASSQRNDGSSGKHVSGS 59

Query: 3075 VSPNCENTYSRRNKVVSVATSFKPSQVDLASSSRKSEGVSNQQKVSMNKPSSKTAELEDS 2896
            +SPN +N+  ++ K VS  ++ KP+    A+SS  S  ++++ + S  K           
Sbjct: 60   LSPNGQNSSLQKGKAVSKTSAGKPT----AASSNASTSIADKSRCSPQKN---------- 105

Query: 2895 DDEKPLSFRLAGTPLGINKESRTPLMK-IKPEDATSDDSDDEKPLSFRIPASGS------ 2737
                          L IN   +  L K         DDSDD+KPLSFR+  SGS      
Sbjct: 106  --------------LAINNMQKQQLNKPCNGPKEDPDDSDDDKPLSFRLATSGSSLKIKS 151

Query: 2736 --GASQNSLNLKKKLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGATKNESPDSD 2563
              G   +   +   L                                     K +S    
Sbjct: 152  QPGTKGHGSPVPSSLQMDKTKITCKKSSADSEDEIPLSSKFQLKTNVGSSVKKYDS---- 207

Query: 2562 DDDKPLAARFQQNGYSKNGSQISRHLLSGSGKRPSTSADKSALAANKKPKFSEGISQNKV 2383
            D++KPL  +FQQNG SK  +++S+ L S   KRP +  + S  +  KKPK SE I     
Sbjct: 208  DEEKPLIFKFQQNGSSKKDNELSKSLKS-LNKRPMSDVNTSGQSLVKKPKLSESIPAKVK 266

Query: 2382 KPEHSXXXXXXXXDYVPISQRLXXXXXXXXXXXXXXKVLNKVVXXXXXXXXXXXXXXXXX 2203
            +            D +PISQRL              K   KVV                 
Sbjct: 267  QAPIKSEPKEDDEDNIPISQRLKKSAPSDNKSSSTKKTTTKVVSSSFKKTSKKLKKDKYS 326

Query: 2202 XXXXXSTVPPGSGEGQKWTTLEHSGVIFPPAYKPHGVKMLYDGKPVNLTPEQEEVATMFA 2023
                   VPP SGEGQKWTTLEH+GVIFPP YKPHGVKMLY+G+PV+LTPEQEEVATMFA
Sbjct: 327  KSTK---VPPSSGEGQKWTTLEHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFA 383

Query: 2022 VMKDTDYAAKKTFITNFWNDWKEILGENHVIKDFAQCDFTPIYEWHLKEKEKKKQMSTXX 1843
            VMKDT+YA K+ F+ NF NDWK ILG+NHVIK F  CDFTPIYEWH +EKEKKKQMS   
Sbjct: 384  VMKDTEYATKQKFVENFMNDWKVILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSAEE 443

Query: 1842 XXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPHDIT 1663
                         KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI P+DIT
Sbjct: 444  KKALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDIT 503

Query: 1662 INIGKGVPIPECPIPGERWKEIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDK 1483
            INIGKG P+PECPIPGERWKE+KHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDK
Sbjct: 504  INIGKGAPVPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDK 563

Query: 1482 EKYEKARKLKDYIQTIRANYTKDFTSKDESRRQIAVATYLIDKLALRAGNEKDDDEADTV 1303
            EKYEKAR LKDYI+ IRANYT+DF+SKD ++RQIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 564  EKYEKARLLKDYIKDIRANYTRDFSSKDIAKRQIAVATYLIDKLALRAGNEKDDDEADTV 623

Query: 1302 GCCTLKVENVALVPPNQIQFDFLGKDSIRYFNTVVVEPAVYKAIGEFXXXXXXXXXXXXN 1123
            GCCTLKVENV L+PPN++QFDFLGKDSIRYFNTV VE  VYKAIG+F             
Sbjct: 624  GCCTLKVENVELIPPNKLQFDFLGKDSIRYFNTVEVELPVYKAIGQF-------KEGKKE 676

Query: 1122 SDDLFDKLDTSKLNTHLKELMPGLTAKVFRTYNASITLDQMLNKETRDGTVQEKIAVYQT 943
             +DLFDKLDTSKLN HLKELMPGLTAKVFRTYNASITLD MLNKET+DG V EKI VYQ 
Sbjct: 677  GEDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKETKDGDVAEKITVYQH 736

Query: 942  ANKEVAIICNHQRSVSKTHDAQMSRLNEKIEELKAQREELKEDLHRARKGKPPLKDAEGK 763
            ANKEVAIICNHQRSVSK+H AQM+RL++KI+ELK   +ELK DL RA+KGKPPLK A+GK
Sbjct: 737  ANKEVAIICNHQRSVSKSHSAQMNRLDDKIKELKELLDELKTDLARAKKGKPPLKGADGK 796

Query: 762  PKRNMAPDALEKKLSQVDAKIEKMELDKKIKDDLKTVALGTSKINYLDPRITVAWCKRYE 583
            PKRN+ P+ALE+K++Q +AKIEKME DK+IK+DLKTVALGTSKINYLDPRI+VAWCKR+E
Sbjct: 797  PKRNLTPEALERKIAQANAKIEKMERDKQIKEDLKTVALGTSKINYLDPRISVAWCKRHE 856

Query: 582  VPIEKIFNKSLLAKFTWAMDADPSFRF 502
            VPIEKIFNKSLLAKF WAMD DPSFRF
Sbjct: 857  VPIEKIFNKSLLAKFAWAMDVDPSFRF 883


>XP_008798752.1 PREDICTED: DNA topoisomerase 1-like [Phoenix dactylifera]
          Length = 948

 Score =  977 bits (2526), Expect = 0.0
 Identities = 524/895 (58%), Positives = 606/895 (67%), Gaps = 46/895 (5%)
 Frame = -3

Query: 3048 SRRNKVVSVATSFKPSQVDLASSSRKSEGVSNQQKVSMNKPSSKTAELEDSDDEKPLSFR 2869
            S ++K +   ++ + +  D +    + +  SN  K +     +     +DSDD+KPLS R
Sbjct: 81   SEKSKSIIAGSNSRTALPDQSKHFAEQKLTSNNNKTTHYNFCANAENSDDSDDDKPLSHR 140

Query: 2868 LAGTPLGINKESRTPLMKI--------------------KP--EDATSDDSDDEKPLSFR 2755
            L      + K +   + K+                    KP  ++  SDDSDD+KPLS +
Sbjct: 141  LNAVSTVVQKNNSMHMEKVVNHSSEHKLATSCKGKMTLDKPCGKNEDSDDSDDDKPLSSK 200

Query: 2754 IPASGSGASQNSLNLKKKLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGATKNES 2575
              +S      +SL+ K+ L                                   +TK +S
Sbjct: 201  FSSSVVAGKNSSLHAKQALESPRHTSLSSQKPKE--------------------STKEDS 240

Query: 2574 PDSDDDDKPLAARFQQNGY----SKNGSQISRHLLS-------------------GSGKR 2464
             DS+DD KPL +RFQ        +KN   + + L S                   G+ KR
Sbjct: 241  DDSEDD-KPLLSRFQPKSTGGASTKNSHSVEKPLASKVKPNGSIKKEASNESNPKGANKR 299

Query: 2463 PSTSADKSALAANKKPKFSEGISQNKVKPEH-SXXXXXXXXDYVPISQRLXXXXXXXXXX 2287
            P    +    ++ KK K S+     K+K E           D++P++QR+          
Sbjct: 300  PLGDTNNPIYSSIKKAKVSDSSHPIKIKQEVVKKETDKDDDDHIPVAQRIKKSGSSDNKS 359

Query: 2286 XXXXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIFPPAY 2107
                 +                             VPPGSG GQKWTTLEH+GVIFPP Y
Sbjct: 360  STNKVMKKITSSSFKKDGKKMKKALKGSKFSKSLNVPPGSGGGQKWTTLEHNGVIFPPPY 419

Query: 2106 KPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHVIK 1927
            KPHGVKMLY+G+ V+LTPEQEEVATMFAVMKDTDYA K  FI NFWNDWK+ILG++HVIK
Sbjct: 420  KPHGVKMLYNGQLVDLTPEQEEVATMFAVMKDTDYATKPKFIENFWNDWKQILGKSHVIK 479

Query: 1926 DFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRV 1747
             F  CDFTPIYEWHL+EKEKKKQMS                KYMWAIVDGVKEKVGNFRV
Sbjct: 480  KFELCDFTPIYEWHLREKEKKKQMSAEEKKALKEEKLKQEEKYMWAIVDGVKEKVGNFRV 539

Query: 1746 EPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTVTWLA 1567
            EPPGLFRGRGEHPKMGKLKKRI P DITINIGKG PIPECP+PGERWKE+KH+NTVTWLA
Sbjct: 540  EPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKGAPIPECPVPGERWKEVKHENTVTWLA 599

Query: 1566 FWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDESRR 1387
            FWNDPINPKEFKYVFLAASS+LKGQSDKEKYEKAR LKDYI  IRANYT+DFTSKD ++R
Sbjct: 600  FWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHNIRANYTRDFTSKDATKR 659

Query: 1386 QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRYFN 1207
            QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV L+PPN++QFDFLGKDSIRYFN
Sbjct: 660  QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVVLIPPNKLQFDFLGKDSIRYFN 719

Query: 1206 TVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRTY 1027
            TV VE  VYKAIGEF            + +DLFD LDTSKLN HLKELMPGLTAKVFRT+
Sbjct: 720  TVEVELPVYKAIGEF------RTARKSDGEDLFDLLDTSKLNAHLKELMPGLTAKVFRTF 773

Query: 1026 NASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKIEE 847
            NASITLD +LNKET++GT+ EKIAVYQ A K+VAIICNHQRSVSK+HDAQMSRLNEKI +
Sbjct: 774  NASITLDDILNKETKEGTLPEKIAVYQHATKQVAIICNHQRSVSKSHDAQMSRLNEKIMD 833

Query: 846  LKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKIKD 667
            LK QREELK DL RARKGKPPLKD EGK KRN++P+ALEKK++Q+DAKIEKMELDKKIK+
Sbjct: 834  LKTQREELKVDLSRARKGKPPLKDREGKTKRNLSPEALEKKIAQIDAKIEKMELDKKIKE 893

Query: 666  DLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            DLKTVALGTSKINYLDPRI+VAWCKR+EVPIEKIFNKSLL KF WAMD DP FRF
Sbjct: 894  DLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLGKFAWAMDVDPGFRF 948


>XP_009407901.1 PREDICTED: DNA topoisomerase 1-like isoform X2 [Musa acuminata subsp.
            malaccensis] XP_009407902.1 PREDICTED: DNA topoisomerase
            1-like isoform X1 [Musa acuminata subsp. malaccensis]
          Length = 951

 Score =  976 bits (2524), Expect = 0.0
 Identities = 546/956 (57%), Positives = 630/956 (65%), Gaps = 39/956 (4%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRRNXXXXXXXXXXXXXXXXXATPNPSLVKCPASQV 3073
            M+VHGCV+Q I DN     + PIIF+R                             ++Q 
Sbjct: 1    MSVHGCVNQVIDDN-GEDDEGPIIFKRPNSSSKQSRLICSSKKTAPQKYDGF-NITSNQN 58

Query: 3072 SPNCENTYSRRNKVVSVA--TSFKPSQVDLASSSRKSEGVSNQQKVSMN--------KPS 2923
              N +N++ +  KV S    +S KP+    +S S  S   ++  K + N        K S
Sbjct: 59   VGNGDNSHFQNAKVFSTVKPSSEKPNVAISSSRSWASVQDTSYHKSTTNDVGLEHQDKSS 118

Query: 2922 SKTAELEDSDDEKPLSFRLAGTPLGINKESRTPLMKI--------------------KP- 2806
             +  EL+DS+D+KPLS RL    + + K++ T L KI                    KP 
Sbjct: 119  PEVQELDDSNDDKPLSHRLNSVSVAVQKKNSTDLEKIDMHSLDHKFVKKSTDKMDLDKPI 178

Query: 2805 -EDATSDDSDDEKPLSFRIPASGSGASQNSLNLKK-----KLTXXXXXXXXXXXXXXXXX 2644
             ++  SD SDD+KPLS++  +S +        + K     K T                 
Sbjct: 179  IKNEDSDYSDDDKPLSYKFSSSAAVNKSGFSRVMKAPQSSKPTSPPSMKMNSNIEGFSDD 238

Query: 2643 XXXXXXXXXXXXXXSLGATKNESPDSDDDDKPLAARFQQNGYSKNGSQISRHLLSGSGKR 2464
                          + G +  +   S+ D+KP +++ + +G SK           G  KR
Sbjct: 239  SEDEKPLLSRFQSKATGGSSMKG--SNSDEKPFSSKLKVHGSSKKEGNSDNTFPKGGQKR 296

Query: 2463 PSTSADKSALAANKKPKFSEGISQNKVKPEHSXXXXXXXXD--YVPISQRLXXXXXXXXX 2290
            P      +  +  KK K SE  +  KVK E +        D   +PI+QR+         
Sbjct: 297  PLGGIKPTESSNIKKVKVSETPASVKVKHEIAVKKEIKADDSDQIPIAQRMKKTVSSNST 356

Query: 2289 XXXXXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIFPPA 2110
                  VL+K                          VPPGSG GQKWTTLEH+GVIFPP 
Sbjct: 357  SVSKS-VLHKTHSSFKTDGKKMKTNMKDFKYSKSLKVPPGSGGGQKWTTLEHNGVIFPPP 415

Query: 2109 YKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHVI 1930
            YKPHGVKMLY+G+PV+LTPEQEEVATMFAVMKDTDYA KK FI NF NDW++ILG+NHVI
Sbjct: 416  YKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKKQFIENFMNDWRQILGKNHVI 475

Query: 1929 KDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFR 1750
            K F  CDFTPI EWHL+EKEKKKQMS                KYMWAIVD VKEKVGNFR
Sbjct: 476  KKFELCDFTPINEWHLREKEKKKQMSAEEKKAVKEEKLKQEEKYMWAIVDDVKEKVGNFR 535

Query: 1749 VEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTVTWL 1570
            VEPPGLFRGRGEHPKMGKLKKRI P DITINIGK  PIPECPI GERWKEIKHDNTVTWL
Sbjct: 536  VEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPISGERWKEIKHDNTVTWL 595

Query: 1569 AFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDESR 1390
            AFWNDPINPKEFKYVFLAASSSLKGQSD+EKYEKAR LKDYI  IRANYT+DF SKD ++
Sbjct: 596  AFWNDPINPKEFKYVFLAASSSLKGQSDREKYEKARLLKDYIHNIRANYTRDFASKDPTK 655

Query: 1389 RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRYF 1210
            +QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV LVPPN ++FDFLGKDSIRY 
Sbjct: 656  QQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPNMLKFDFLGKDSIRYL 715

Query: 1209 NTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRT 1030
            NTV VE  VYKAIGEF              DDLFD LDTSKLN HLKELMPGLTAKVFRT
Sbjct: 716  NTVEVELPVYKAIGEFQTAKKSDGGRKGKGDDLFDLLDTSKLNAHLKELMPGLTAKVFRT 775

Query: 1029 YNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKIE 850
            YNASITLD +LNKET+DG+V EKIAVYQ ANKEVAIICNHQRSVSK+H+ QMSRLNEKI 
Sbjct: 776  YNASITLDDILNKETKDGSVPEKIAVYQHANKEVAIICNHQRSVSKSHENQMSRLNEKIN 835

Query: 849  ELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKIK 670
            +LKAQR+ELK DL RARKGKPPLKD EGK K+N++P+ +EKKLSQVDAKIEK+ELDK+IK
Sbjct: 836  DLKAQRDELKMDLSRARKGKPPLKDKEGKTKKNLSPEVIEKKLSQVDAKIEKLELDKQIK 895

Query: 669  DDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            +DLKTVALGTSKINYLDPRI+VAWCKR+EVPIEKIFNKSLLAKF WAMD +P+FRF
Sbjct: 896  EDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVEPNFRF 951


>XP_010266803.1 PREDICTED: DNA topoisomerase 1 alpha-like [Nelumbo nucifera]
          Length = 890

 Score =  966 bits (2497), Expect = 0.0
 Identities = 542/933 (58%), Positives = 622/933 (66%), Gaps = 15/933 (1%)
 Frame = -3

Query: 3255 LMAVHGCVSQKIVDNLXXXXDEPIIFRRNXXXXXXXXXXXXXXXXXATPNP-SLVKCPAS 3079
            +MAV  C+  K  D+     + PIIF+RN                 +     S  KC + 
Sbjct: 1    MMAVDACIKPKFFDD-GDDDEGPIIFKRNNASSKKNQLNKELKKVSSRKRDGSSGKCVSD 59

Query: 3078 QVSPNCENTYSRRNKVV---------SVATSFKPSQV---DLASSSRKSEGVSNQQKVSM 2935
              SPN +N+  ++ K V         S  TS K S      L  S +K+  + N +K  +
Sbjct: 60   SFSPNGQNSSLQKGKAVQSSKASTGKSTETSSKASTSITDKLKCSPQKNSSIDNMEK-QL 118

Query: 2934 NKPSSKT-AELEDSDDEKPLSFRLAGTPLGINKESRTPLMKIKPEDATSDDSDDEKPLSF 2758
             KP ++   +  DSDD+KPLS RL  T   + K   +P+ K       S  S  EK    
Sbjct: 119  KKPCNEPYTDSVDSDDDKPLSIRLP-TSASLLKCKSSPVSKGLSSPVASS-SQSEKTNVT 176

Query: 2757 RIPASGSGASQNSLNLKKKLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGATKNE 2578
               +S     +  L+LK KL                                 +G +  +
Sbjct: 177  NKKSSEDSEDELPLSLKLKLKPS------------------------------VGLSGKK 206

Query: 2577 SPDSDDDDKPLAARFQQNGYSKNGSQISRHLLSGSGKRPSTSADKSALAANKKPKFSEGI 2398
              DS ++ KPL ++ QQNG SK  ++  +       KRP + A+ S  +  KK K SE  
Sbjct: 207  FYDSGEE-KPLVSKLQQNGSSKRDNEPLKSP-KNLNKRPLSGANSSGQSLVKKLKVSEVS 264

Query: 2397 SQNKVKPEH-SXXXXXXXXDYVPISQRLXXXXXXXXXXXXXXKVLNKVVXXXXXXXXXXX 2221
               KVK             D +PISQRL              K    V            
Sbjct: 265  VPTKVKQTSIKSEPKEEDEDDIPISQRLKKSASSDDKSLSLKKTTKVVSSSFKKTTNKLK 324

Query: 2220 XXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIFPPAYKPHGVKMLYDGKPVNLTPEQEE 2041
                       + +PP SGEGQKWTTLEH+GVIFPP YKPHGVKMLY+GKPV+LTPEQEE
Sbjct: 325  KAAKNSKYSKSTKMPPSSGEGQKWTTLEHNGVIFPPLYKPHGVKMLYNGKPVDLTPEQEE 384

Query: 2040 VATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHVIKDFAQCDFTPIYEWHLKEKEKKK 1861
            VATMFAVMKDTDYA K  FI NF NDW+ ILG+NHVIK F  CDFTPIYEWH +EKEKKK
Sbjct: 385  VATMFAVMKDTDYATKSRFIENFMNDWRTILGKNHVIKKFELCDFTPIYEWHQREKEKKK 444

Query: 1860 QMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1681
            QMS                KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI
Sbjct: 445  QMSAEEKKALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 504

Query: 1680 YPHDITINIGKGVPIPECPIPGERWKEIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSL 1501
            +P DITINIGKG PIPECPIPGERWKE++HDNTVTWLAFWNDPINPKEFKYVFLAASSSL
Sbjct: 505  HPSDITINIGKGAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSL 564

Query: 1500 KGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDESRRQIAVATYLIDKLALRAGNEKDD 1321
            KGQSDKEKYEKAR LKDYI+ IRANYT+DF SKD ++RQIAVATYLIDKLALRAGNEKDD
Sbjct: 565  KGQSDKEKYEKARLLKDYIKDIRANYTRDFVSKDITKRQIAVATYLIDKLALRAGNEKDD 624

Query: 1320 DEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRYFNTVVVEPAVYKAIGEFXXXXXXX 1141
            DEADTVGCCTLKVENV LVPPN++QFDFLGKDSIRYFNTV VE AVYKAIG+F       
Sbjct: 625  DEADTVGCCTLKVENVELVPPNKLQFDFLGKDSIRYFNTVEVELAVYKAIGQF------- 677

Query: 1140 XXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRTYNASITLDQMLNKETRDGTVQEK 961
                 + +DLFD LDTSKLN HLKELMPGLTAKVFRTYNASITLD+MLN+E++ G V EK
Sbjct: 678  KNGKEDGEDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNRESKGGDVAEK 737

Query: 960  IAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKIEELKAQREELKEDLHRARKGKPPL 781
            IAVYQ ANKEVAIICNHQRSVSK+H AQM RL++KI+ELK   +ELK DL RA+KGKPPL
Sbjct: 738  IAVYQHANKEVAIICNHQRSVSKSHSAQMHRLDDKIKELKDALDELKTDLARAKKGKPPL 797

Query: 780  KDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKIKDDLKTVALGTSKINYLDPRITVA 601
            K A+GKPKRN+ P+ALEKK++Q +AKIEKME DK+IK+DLKTVALGTSKINYLDPRI+VA
Sbjct: 798  KGADGKPKRNLTPEALEKKIAQANAKIEKMERDKQIKEDLKTVALGTSKINYLDPRISVA 857

Query: 600  WCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            WCKR+EVPIEKIFNKSLLAKF WAMD DP FRF
Sbjct: 858  WCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF 890


>XP_009411876.1 PREDICTED: DNA topoisomerase 1 [Musa acuminata subsp. malaccensis]
          Length = 926

 Score =  953 bits (2464), Expect = 0.0
 Identities = 533/951 (56%), Positives = 617/951 (64%), Gaps = 34/951 (3%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRRNXXXXXXXXXXXXXXXXXATPNPSLVKCPASQV 3073
            M++HGC++ +++++     + PI F+R+                    N S  +  +S  
Sbjct: 1    MSIHGCIN-RVMNDSGEDEEGPITFKRS--------------------NSSSKQVRSSSA 39

Query: 3072 S----PNCENTYSRRNKVVSVATSFKPSQVDLASSSRKSEGVSNQQKVSMNKPS-SKTAE 2908
            S    P   +  +   K    ++S   S   L   S   +  ++  K      S ++   
Sbjct: 40   SRKTAPQKHDAKATIEKPFVSSSSSHSSIPALTKHSSNCKSTTSHVKPQHQDESIAEVQN 99

Query: 2907 LEDSDDEKPLSFRLAGTPLGINKESRTPLMKIKPEDAT---------------------- 2794
             +DSDD+KPLS RL    + + K+      KI    +                       
Sbjct: 100  SDDSDDDKPLSHRLNSASVAVQKKFFMDSEKIHKHSSDHYFAKNNTNKMIVDKSIIRNEE 159

Query: 2793 SDDSDDEKPLSFRIP---ASGSGASQNSLNLKK--KLTXXXXXXXXXXXXXXXXXXXXXX 2629
            S+DSDD KPLS +I    A  +G   + + L +  K T                      
Sbjct: 160  SNDSDDNKPLSSKISSIAACSTGGPSHVVKLPQSAKPTSHPSMKVNSNIKEDSDDSEDEK 219

Query: 2628 XXXXXXXXXSLGATKNESPDSDDDDKPLAARFQQNGYSKNGSQISRHLLSGSGKRPSTSA 2449
                       G +  ++PDS    K L+ + + N  SK  +        G  KR     
Sbjct: 220  PLISRFQSKVFGGSSVKNPDSYQ--KSLSPKLKFNASSKKEASKEIRSPKGGQKRALGDT 277

Query: 2448 DKSALAANKKPKFSEGISQNKVKPEHSXXXXXXXXD--YVPISQRLXXXXXXXXXXXXXX 2275
              S  ++ KK K SE     KVK E +        D  ++PI+QR+              
Sbjct: 278  KTSDSSSIKKAKVSETSFLVKVKNEVAVKKEVKEDDNDHIPIAQRMKKSVSSNSTSTTKN 337

Query: 2274 KVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIFPPAYKPHG 2095
              L K                          VPPGSG GQKWTTLEH+GVIFPP YKPHG
Sbjct: 338  --LLKKTSSFKKDSKQMKKKMKDSKFSKTLKVPPGSGGGQKWTTLEHNGVIFPPPYKPHG 395

Query: 2094 VKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHVIKDFAQ 1915
            VKMLY+G+PV+LTPEQEEVATMFAVMKDT+YA KK FI NF  DW++ILG+NH+IK F  
Sbjct: 396  VKMLYNGQPVDLTPEQEEVATMFAVMKDTEYATKKQFIENFMYDWRQILGKNHIIKKFEL 455

Query: 1914 CDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPG 1735
            CDFTPIYEWHL+EKEKKKQMS                KYMWAIVDGVKEKVGNFRVEPPG
Sbjct: 456  CDFTPIYEWHLREKEKKKQMSGEEKKALKEEKMKQEEKYMWAIVDGVKEKVGNFRVEPPG 515

Query: 1734 LFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTVTWLAFWND 1555
            LFRGRGEHPKMGKLKKRI P DITINIGK  PIPECPIPGERWKE+KHDNTVTWLAFWND
Sbjct: 516  LFRGRGEHPKMGKLKKRIRPRDITINIGKNAPIPECPIPGERWKEVKHDNTVTWLAFWND 575

Query: 1554 PINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDESRRQIAV 1375
            PINPKEFKYVFLAASSSLKGQSDKEKYEKAR+L D IQ IRANYT+DF+SKD ++RQIAV
Sbjct: 576  PINPKEFKYVFLAASSSLKGQSDKEKYEKARRLTDCIQNIRANYTRDFSSKDPTKRQIAV 635

Query: 1374 ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRYFNTVVV 1195
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV LVPPN ++FDFLGKDSIRY NTV V
Sbjct: 636  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPNMLKFDFLGKDSIRYLNTVEV 695

Query: 1194 EPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRTYNASI 1015
            E  VYKAIGEF              DDLFD LDTSKLN HLKELMPGLTAKVFRTYNASI
Sbjct: 696  ELPVYKAIGEFQTAKKSGGGRKGKGDDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASI 755

Query: 1014 TLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKIEELKAQ 835
            TLD +LNKET+DGT+ EKIAVYQ ANKEVAIICNHQRSVSK+H++QMSRLNEKI +LKAQ
Sbjct: 756  TLDDILNKETKDGTLPEKIAVYQHANKEVAIICNHQRSVSKSHESQMSRLNEKINDLKAQ 815

Query: 834  REELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKIKDDLKT 655
            R+EL  DL+RARKGKPPLKD EGK K+N++PD +EKKL QVDAKIEKMELDK+IK+DLKT
Sbjct: 816  RDELNMDLNRARKGKPPLKDKEGKTKKNLSPDVIEKKLVQVDAKIEKMELDKRIKEDLKT 875

Query: 654  VALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            VALGTSKINYLDPRI+VAWCKR+EVPIEKIFNKSLLAKF WAMD DP FRF
Sbjct: 876  VALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF 926


>OAY66604.1 DNA topoisomerase 1 [Ananas comosus]
          Length = 970

 Score =  944 bits (2440), Expect = 0.0
 Identities = 530/976 (54%), Positives = 626/976 (64%), Gaps = 59/976 (6%)
 Frame = -3

Query: 3252 MAVHGCVSQKIVDNLXXXXDEPIIFRRNXXXXXXXXXXXXXXXXXATPNPSLVKCPASQV 3073
            MAV GCV+  I DN     D P+ F+R+                    + SL +  +   
Sbjct: 1    MAVDGCVNPVIYDN-GDDDDAPLTFKRSSSSRHSSLNSTSNKSTSQKRDISLQRARSDHS 59

Query: 3072 SPNCENTYSRRNKVVSVATSFK-----PSQVDLAS-------SSRKSEGVSNQQKVSMNK 2929
            SPN EN+  +++K  S +         P+ V  +S       SS      S+  K ++ +
Sbjct: 60   SPNGENSNLQKSKGTSTSKMPTERPKIPNPVSRSSVPGPPNHSSENKHTTSSMDKTNLKR 119

Query: 2928 PSSKTAELEDSDDEKPLSFRLAGT-------------------PLGINKESRTPLM---- 2818
            P   +   +DSDD  PLS R                       P   + +   PL+    
Sbjct: 120  PHENS---DDSDDNIPLSQRANPASKMVKHFSEQRDTSHGKVEPSSDSDDDNKPLISKYS 176

Query: 2817 ------------KIKPEDATSDDSDDEKPLSFRIPASGSGA--------SQNSLNLKKKL 2698
                        K +    ++DDS+D+KPL+ ++ A+ S A        S   +N   K 
Sbjct: 177  SVGAGKVPASSSKNRSGKESADDSEDKKPLASKVKANASTAGAEHVASSSARKINSSSKE 236

Query: 2697 TXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGATKNESPDSDDDDKPLAARFQQNGY 2518
                                               ++ +++ DS+D  KPLA++ + N  
Sbjct: 237  NADDSEDEKPLAFKFKANAATTGAGQVASSSSKKISSSSKANDSEDR-KPLASKIKANMS 295

Query: 2517 SKNGSQISRHLLSGSGKRPSTSADKSALAANKKPKFSEGISQNKVKPEH--SXXXXXXXX 2344
             K  +           KR     +    +  KK K S+  +  KVK E            
Sbjct: 296  IKKETGNESRSPKDINKRTLGDVNNRNDSLVKKAKVSDNSAFVKVKHESVVKKELKTDDG 355

Query: 2343 DYVPISQRLXXXXXXXXXXXXXXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXST--VPPG 2170
            D  P+++++               V+ K                         +  VPPG
Sbjct: 356  DRKPLAEKMRKLGSSDSKSSTTK-VIKKTTPSSKKDGKKLKMKKAMKKSTFSKSLKVPPG 414

Query: 2169 SGEGQKWTTLEHSGVIFPPAYKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKK 1990
            SG GQKWTTLEH+GVIFPP Y+PHGVKMLY+G+PV+LTPEQEEVATMFAVMKDTDYA K 
Sbjct: 415  SGGGQKWTTLEHNGVIFPPPYQPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKP 474

Query: 1989 TFITNFWNDWKEILGENHVIKDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXX 1810
             FI NF+NDW+++LG+NHVIK F  CDFTPIYEWHLKEKEKKKQMS              
Sbjct: 475  KFIHNFFNDWRQVLGKNHVIKKFELCDFTPIYEWHLKEKEKKKQMSAAEKKALKEEKLKK 534

Query: 1809 XXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPE 1630
              KYMWAIVDGVKEKVGNFRVEPP LFRGRGEHPKMGKLK+RI P DITINIGK  PIPE
Sbjct: 535  EDKYMWAIVDGVKEKVGNFRVEPPALFRGRGEHPKMGKLKRRIRPSDITINIGKNAPIPE 594

Query: 1629 CPIPGERWKEIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKD 1450
            CPIPGERW+E+KHDNTVTWLA+W+DPINPK+ KYVFLAASSSLKGQSDKEKYEKAR+LKD
Sbjct: 595  CPIPGERWREVKHDNTVTWLAYWSDPINPKDSKYVFLAASSSLKGQSDKEKYEKARQLKD 654

Query: 1449 YIQTIRANYTKDFTSKDESRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVA 1270
            YI  IR+ YTKDF SKD ++RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 
Sbjct: 655  YIHNIRSTYTKDFNSKDPTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVI 714

Query: 1269 LVPPNQIQFDFLGKDSIRYFNTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTS 1090
             VPPNQ+QFDFLGKDSIRYFNTV VE  VYKAIGEF            + DDLFD LDTS
Sbjct: 715  CVPPNQLQFDFLGKDSIRYFNTVEVEAPVYKAIGEFRTARKGDGKRKGDGDDLFDLLDTS 774

Query: 1089 KLNTHLKELMPGLTAKVFRTYNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNH 910
            KLN HLKELMPGLTAKVFRTYNASITLD +LNKET++GT+ EKIAVYQ ANKEVAIICNH
Sbjct: 775  KLNAHLKELMPGLTAKVFRTYNASITLDDILNKETKEGTLPEKIAVYQRANKEVAIICNH 834

Query: 909  QRSVSKTHDAQMSRLNEKIEELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALE 730
            QRSVSK+H++QMSRLNEKI+ELKA REELK DL RARKGKPPLKDA+GK KRN++P+A++
Sbjct: 835  QRSVSKSHESQMSRLNEKIDELKALREELKVDLSRARKGKPPLKDADGKTKRNLSPEAIQ 894

Query: 729  KKLSQVDAKIEKMELDKKIKDDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSL 550
            KKL+Q +AKIEKMELDKKIK+DLKTVALGTSKINYLDPRI+VAWCKR+EVPIEKIFNKSL
Sbjct: 895  KKLAQTNAKIEKMELDKKIKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSL 954

Query: 549  LAKFTWAMDADPSFRF 502
            LAKF WAMD DPS+RF
Sbjct: 955  LAKFAWAMDVDPSYRF 970


>XP_020111558.1 DNA topoisomerase 1 beta-like isoform X1 [Ananas comosus]
          Length = 970

 Score =  942 bits (2436), Expect = 0.0
 Identities = 504/839 (60%), Positives = 585/839 (69%), Gaps = 13/839 (1%)
 Frame = -3

Query: 2979 SRKSEGVSNQQKVSMNKPSSKTAELEDSDDEKPLSFRLAG--TPLGINKESRTPLMKIKP 2806
            S+ S   + +   S +K  S     +DS+D+KPL+ ++    +  G    + +   KI  
Sbjct: 173  SKYSSVGAGKVPASSSKNRSGKESADDSEDKKPLASKVKANASTAGAEHVASSSARKINS 232

Query: 2805 EDA-TSDDSDDEKPLSFRIPASGS--GASQNSLNLKKKLTXXXXXXXXXXXXXXXXXXXX 2635
                 +DDS+DEKPL+F+  A+ +  GA Q + +  KK+                     
Sbjct: 233  SSKENADDSEDEKPLAFKFKANAATTGAGQVASSSSKKIN-------------------- 272

Query: 2634 XXXXXXXXXXXSLGATKNESPDSDDDDKPLAARFQQNGYSKNGSQISRHLLSGSGKRPST 2455
                             +   +  +D KPLA++ + N   K  +           KR   
Sbjct: 273  ----------------SSSKANDSEDRKPLASKIKANMSIKKETGSESRSPKDINKRTLG 316

Query: 2454 SADKSALAANKKPKFSEGISQNKVKPEH--SXXXXXXXXDYVPISQRLXXXXXXXXXXXX 2281
              +    +  KK K S+  +  KVK E            D  P+++++            
Sbjct: 317  DVNNRNDSLVKKAKVSDNSAFVKVKHESVVKKELKTDDGDRKPLAEKMRKLGSSDSKSST 376

Query: 2280 XXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXST------VPPGSGEGQKWTTLEHSGVIF 2119
                  KV+                      ST      VPPGSG GQKWTTLEH+GVIF
Sbjct: 377  -----TKVIKKPTPSSKKDGKKLKMKKAMKKSTFSKSLKVPPGSGGGQKWTTLEHNGVIF 431

Query: 2118 PPAYKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGEN 1939
            PP Y+PHGVKMLY+G+PV+LTPEQEEVATMFAVMKDTDYA K  FI NF+NDW+++LG+N
Sbjct: 432  PPPYQPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPKFIHNFFNDWRQVLGKN 491

Query: 1938 HVIKDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVG 1759
            HVIK F  CDFTPIYEWHLKEKEKKKQMS                KYMWAIVDGVKEKVG
Sbjct: 492  HVIKKFELCDFTPIYEWHLKEKEKKKQMSAAEKKALKEEKLKKEDKYMWAIVDGVKEKVG 551

Query: 1758 NFRVEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTV 1579
            NFRVEPP LFRGRGEHPKMGKLK+RI P DITINIGK  PIPECPIPGERW+E+KHDNTV
Sbjct: 552  NFRVEPPALFRGRGEHPKMGKLKRRIRPSDITINIGKNAPIPECPIPGERWREVKHDNTV 611

Query: 1578 TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKD 1399
            TWLA+W+DPINPK+ KYVFLAASSSLKGQSDKEKYEKAR+LKDYI  IR+ YTKDF SKD
Sbjct: 612  TWLAYWSDPINPKDSKYVFLAASSSLKGQSDKEKYEKARQLKDYIHNIRSTYTKDFNSKD 671

Query: 1398 ESRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSI 1219
             ++RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV  VPPNQ+QFDFLGKDSI
Sbjct: 672  PTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVICVPPNQLQFDFLGKDSI 731

Query: 1218 RYFNTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKV 1039
            RYFNTV VE  VYKAIGEF            + DDLFD LDTSKLN HLKELMPGLTAKV
Sbjct: 732  RYFNTVEVEAPVYKAIGEFRTAKKGDGKRKGDGDDLFDLLDTSKLNAHLKELMPGLTAKV 791

Query: 1038 FRTYNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNE 859
            FRTYNASITLD +LNKET++GT+ EKIAVYQ ANKEVAIICNHQRSVSK+H++QMSRLNE
Sbjct: 792  FRTYNASITLDDILNKETKEGTLPEKIAVYQRANKEVAIICNHQRSVSKSHESQMSRLNE 851

Query: 858  KIEELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDK 679
            KI+ELKA REELK DL RARKGKPPLKDA+GK KRN++P+A++KKL+Q +AKIEKMELDK
Sbjct: 852  KIDELKALREELKVDLSRARKGKPPLKDADGKTKRNLSPEAIQKKLAQTNAKIEKMELDK 911

Query: 678  KIKDDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            KIK+DLKTVALGTSKINYLDPRI+VAWCKR+EVPIEKIFNKSLLAKF WAMD DPS+RF
Sbjct: 912  KIKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSYRF 970


>KMZ57043.1 DNA topoisomerase 1 [Zostera marina]
          Length = 971

 Score =  938 bits (2425), Expect = 0.0
 Identities = 506/839 (60%), Positives = 586/839 (69%), Gaps = 14/839 (1%)
 Frame = -3

Query: 2976 RKSEGVSNQQKVSMNKPSSKTAELEDSDDEKPLSFRLAGTPLGINKESRT-PLMKIKPED 2800
            R ++       V   K   +T   E+SDD+KPL F+         K+  + P  K+K E 
Sbjct: 160  RHTKVTKQMNSVPCKKIKEETCATENSDDDKPLIFKRNLHSAAHTKQMNSLPCKKLK-EV 218

Query: 2799 ATSDDSDDEKPLSF---------RIPASGSGASQNSLNLKKKLTXXXXXXXXXXXXXXXX 2647
               +DSDD+KP+           ++  SG   S +  N+K                    
Sbjct: 219  HVDEDSDDDKPIDSIRQKVNSLPKMHGSGCSTSPHLQNIKTNA------------HNNGN 266

Query: 2646 XXXXXXXXXXXXXXXSLGATKNESPDSDDDDKPLAARFQQNGYSKNGSQISRHLLSGSGK 2467
                            LG++K  S DS +  KP A+  QQN   K     +   +  + K
Sbjct: 267  VKVEGASSSKIPTNSGLGSSKKRSYDSIEK-KPSASMIQQNSSFKREPNGASKSIINANK 325

Query: 2466 RPSTSADKSALAANKKPKFSEGISQNKVKPE----HSXXXXXXXXDYVPISQRLXXXXXX 2299
            RP  S   S  ++NKK K S+  + +K   +              DYVPIS+++      
Sbjct: 326  RPLGSILNSVQSSNKKVKLSDSPAPSKTTKKLNLKEESRQSSDSDDYVPISRQIKKTISS 385

Query: 2298 XXXXXXXXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIF 2119
                     V  +V+                        V PGSGEGQKWTTLEH+GVIF
Sbjct: 386  NNKSPSKP-VSKRVISKPIQSEKNVKRSNSSK-------VAPGSGEGQKWTTLEHNGVIF 437

Query: 2118 PPAYKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGEN 1939
            PP YKPHG+K+LY+GKPV+LTPEQEEVATMFAVMKDT+YA KKTF+ NF +DWK ILG N
Sbjct: 438  PPPYKPHGIKILYNGKPVDLTPEQEEVATMFAVMKDTEYAKKKTFLDNFMSDWKSILGAN 497

Query: 1938 HVIKDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVG 1759
            HVIK    CDFTPIY+WH++EKEKKK+MS                K+MWAIVDGVKE+VG
Sbjct: 498  HVIKKLELCDFTPIYDWHMREKEKKKEMSAEEKKVLKEEKLQQEEKFMWAIVDGVKERVG 557

Query: 1758 NFRVEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTV 1579
            NFRVEPPGLFRGRGEHPKMGKLK+RI+PHDITINIGK  PIP+ PIPGERWKEIKHDNTV
Sbjct: 558  NFRVEPPGLFRGRGEHPKMGKLKRRIFPHDITINIGKSAPIPKSPIPGERWKEIKHDNTV 617

Query: 1578 TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKD 1399
            TWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR LK+YI  IRANYT+DF +K+
Sbjct: 618  TWLAFWNDPINIKEFKYVFLAASSSLKGQSDKEKYEKARMLKEYIHNIRANYTRDFNNKN 677

Query: 1398 ESRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSI 1219
            E +RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV LV PN++QFDFLGKDSI
Sbjct: 678  EMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVQPNKLQFDFLGKDSI 737

Query: 1218 RYFNTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKV 1039
            RYFNTV VE  VYKAIGEF            N DDLFDKLDTSKLN HLKELMPGLTAKV
Sbjct: 738  RYFNTVEVELPVYKAIGEF-----RKVGEKENGDDLFDKLDTSKLNAHLKELMPGLTAKV 792

Query: 1038 FRTYNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNE 859
            FRTYNASITLDQMLNKET+DG V EKIAVYQ+ANKEVAIICNHQRSVSK+H+AQM+R + 
Sbjct: 793  FRTYNASITLDQMLNKETKDGIVPEKIAVYQSANKEVAIICNHQRSVSKSHEAQMTRFDT 852

Query: 858  KIEELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDK 679
            KI ELK Q+EELK+DL+R RKGKP  KD +GK KRN++ +ALEKKLSQ+DAKIEK+ELDK
Sbjct: 853  KITELKDQQEELKDDLNRIRKGKPLSKDKDGKAKRNLSSEALEKKLSQIDAKIEKIELDK 912

Query: 678  KIKDDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            ++K+DLKTVALGTSKINYLDPRI+VAWCKR EVPIEKIFNKSLLAKF+WAMDA+P+FRF
Sbjct: 913  RLKEDLKTVALGTSKINYLDPRISVAWCKRNEVPIEKIFNKSLLAKFSWAMDAEPTFRF 971


>XP_002265386.1 PREDICTED: DNA topoisomerase 1 alpha isoform X1 [Vitis vinifera]
            XP_010657183.1 PREDICTED: DNA topoisomerase 1 alpha
            isoform X1 [Vitis vinifera] XP_010657184.1 PREDICTED: DNA
            topoisomerase 1 alpha isoform X1 [Vitis vinifera]
          Length = 883

 Score =  937 bits (2423), Expect = 0.0
 Identities = 518/899 (57%), Positives = 598/899 (66%), Gaps = 30/899 (3%)
 Frame = -3

Query: 3108 NPSLVKCPASQVSPNCENTYSRRNKVVSVATSFKPSQVDLASSSRKSEGVSNQQKVSMNK 2929
            N  L+  P +    N E+  S  +K +S   S +  + +       S  V   QK  ++ 
Sbjct: 3    NKQLINPPVA----NGESEDSEDDKPLSAKLSARLPKGNSHVLKGLSSPVLQSQKTKVDV 58

Query: 2928 PSSKTAELEDSDDEKPLSFRL---------AGTPLGINKESRTPLMKIKPEDA------T 2794
              S      DS+DE PLS +          +G  LG +K   +P +   P +       +
Sbjct: 59   KKSDG----DSEDEVPLSSKFPLKTYVRSSSGKSLG-SKGLNSPSLSSHPPETKVGVKES 113

Query: 2793 SDDSDDEKPLSFRIPA-SGSGASQNSLNLKKKLTXXXXXXXXXXXXXXXXXXXXXXXXXX 2617
            SDDS+DE PL  ++   S  GAS + L   K L+                          
Sbjct: 114  SDDSEDEIPLLLKLQLKSRKGASSSKLLDSKGLSSPASSRPQSQKAKVNNKNLSDDSEDE 173

Query: 2616 XXXXXS------LGATKNESPDSDDDDKPLAARFQQNGYSKNGSQISRHLLSGSGKRPST 2455
                        +GA+ ++  D+ D+ KPL +  + NG SK   +  +    G  KRP  
Sbjct: 174  IPLSSKFRLKTGMGASLDKL-DNFDEKKPLTSTLKPNGISKKDDERVKSP-KGQNKRPLG 231

Query: 2454 SADKSALAANKKPKFSEGISQNKVKP--------EHSXXXXXXXXDYVPISQRLXXXXXX 2299
             A+ S  +++KKPK  +G  + KVK         +          +Y P  +RL      
Sbjct: 232  QANTSHHSSSKKPKLLDGSVKGKVKQVSVKAEQKDDDDDDNDDDDEYTPTVKRLKKSVSS 291

Query: 2298 XXXXXXXXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIF 2119
                    KV+                          + VPP SGEGQKWTTLEH+GVIF
Sbjct: 292  DNKKASKTKVIPSSRKKATKKAKKSKKLAKSSKYSKSTKVPPNSGEGQKWTTLEHNGVIF 351

Query: 2118 PPAYKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGEN 1939
            PP YKPHGVKMLY+G+PV+LTPEQEEVATMFAVMKDTDYA K  FI NF NDW+  LG+N
Sbjct: 352  PPPYKPHGVKMLYNGRPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRVRLGKN 411

Query: 1938 HVIKDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVG 1759
            HVIK F  CDFTPIYEWH KEKEKKKQM+T               KYMWA+VDGVKEKVG
Sbjct: 412  HVIKKFELCDFTPIYEWHEKEKEKKKQMTTEEKKALKEEKLKQEDKYMWAVVDGVKEKVG 471

Query: 1758 NFRVEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTV 1579
            NFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIGK  P+PECPIPGERWKE++HDNTV
Sbjct: 472  NFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGKEAPVPECPIPGERWKEVRHDNTV 531

Query: 1578 TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKD 1399
            TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIQ IRA YTKDFT+KD
Sbjct: 532  TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIQNIRATYTKDFTNKD 591

Query: 1398 ESRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSI 1219
              +RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPN+++FDFLGKDSI
Sbjct: 592  TMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNKLEFDFLGKDSI 651

Query: 1218 RYFNTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKV 1039
            RYFNTV VE  VYKAIG+F              DDLFDKLDTSKLN HLKELMPGLTAKV
Sbjct: 652  RYFNTVEVELPVYKAIGQF-------KTGKSGGDDLFDKLDTSKLNAHLKELMPGLTAKV 704

Query: 1038 FRTYNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNE 859
            FRTYNASITLD+MLN+E R G   EKI +YQ ANKEVAIICNHQRSVSK+HD QMSRL+E
Sbjct: 705  FRTYNASITLDEMLNREARGGDAMEKIVIYQHANKEVAIICNHQRSVSKSHDVQMSRLSE 764

Query: 858  KIEELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDK 679
            K+ EL+   +ELK DL RA+KGKPPLKD++GKPK+NM P+ LE+K++Q + KIEKME D 
Sbjct: 765  KMRELQGVLDELKTDLARAKKGKPPLKDSDGKPKKNMTPEVLERKIAQTNTKIEKMERDM 824

Query: 678  KIKDDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            K K+DLKTVALGTSKINYLDPRI+VAWCKR EVPIEKIFNKSLLAKF WAMD DPSFRF
Sbjct: 825  KTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKSLLAKFAWAMDVDPSFRF 883


>XP_006659124.1 PREDICTED: DNA topoisomerase 1-like [Oryza brachyantha]
          Length = 911

 Score =  931 bits (2407), Expect = 0.0
 Identities = 504/898 (56%), Positives = 603/898 (67%), Gaps = 27/898 (3%)
 Frame = -3

Query: 3114 TPNPSLVKCPASQVSPNCENTYSRRNKVVSVATSFKPSQVDLASSSRKS-EGVSNQQKV- 2941
            TPNP     P   V  N    ++  +  +  +   +P   D +  S    + +  ++KV 
Sbjct: 76   TPNPR----PLGSVQLNSSKEHNNNSNAMDKSKLKRPFVEDKSDDSEDDHKPIGLRRKVE 131

Query: 2940 --SMNKPSSKTAELEDSDDEKPLSFRLAGTPLGINKESRTPLMKIKPEDAT-SDDSDDEK 2770
              +  K +  +   +DSDD KPLS ++  T    N  ++  ++K+ P+    +DDS+DEK
Sbjct: 132  DKNFKKAAVGSETADDSDDNKPLSLKINSTKTPSNSTNKASVLKVTPKIVQPADDSEDEK 191

Query: 2769 PLSFRIPASGSGASQNSLNLKKKLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGA 2590
            PL+ R+PA  +                                              L +
Sbjct: 192  PLARRLPAKTT----------------------------------------------LKS 205

Query: 2589 TKNESPDSDDDDKPLAARFQQ-NGYSKNGSQISRHLLSGSGKRPSTSADKS--------- 2440
              N S DS+D+ KPLAARF +  G +      S+  +  +  +PS+S+  S         
Sbjct: 206  GANASDDSEDE-KPLAARFSKVTGSASASISSSKDKVQSANLKPSSSSKVSNNDTNTSRN 264

Query: 2439 -----------ALAANKKPKFSEGISQNKVKPEHSXXXXXXXXDYVPISQRLXXXXXXXX 2293
                       +++A KK + S+      VK E            +P+SQRL        
Sbjct: 265  SIKRPIDNNNQSISALKKARPSDVSVSASVKRESKADDNDN----IPLSQRLKMGESSKS 320

Query: 2292 XXXXXXKVL-NKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIFP 2116
                   V  N                           VPPGSG GQKWTTL H+GVIFP
Sbjct: 321  KPPAKNIVKKNPSSFKKDSKKMKTKKTMKNSQFSKTMKVPPGSGGGQKWTTLVHNGVIFP 380

Query: 2115 PAYKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGENH 1936
            P YKPHGVKMLY+G+PV+LTPEQEEVATMF+VMKDTDYA+K+TFI NF+ DW++ILG+NH
Sbjct: 381  PPYKPHGVKMLYNGQPVDLTPEQEEVATMFSVMKDTDYASKQTFIDNFFTDWRKILGKNH 440

Query: 1935 VIKDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGN 1756
            +IK F  CDFTPIYEWHL+EKEKKKQM++               KYMWA+VDGVKEKVGN
Sbjct: 441  IIKKFELCDFTPIYEWHLREKEKKKQMTSEEKKAVKEEKLKQEEKYMWAVVDGVKEKVGN 500

Query: 1755 FRVEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTVT 1576
            FRVEPPGLFRGRGEHPKMGKLK+RI P DITINIGKG PIPECPIPGE WKE+KHDNTVT
Sbjct: 501  FRVEPPGLFRGRGEHPKMGKLKRRIQPSDITINIGKGAPIPECPIPGESWKEVKHDNTVT 560

Query: 1575 WLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDE 1396
            WLAFWNDPI+ K+FKYVFLAASS+LKGQSDKEKYEK+RKLK +I  IR  YTKDF SKD+
Sbjct: 561  WLAFWNDPISQKDFKYVFLAASSALKGQSDKEKYEKSRKLKHHIHKIRDTYTKDFRSKDK 620

Query: 1395 SRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIR 1216
            +++QIAVATYLIDKLALRAGNEKDDDEA+TVGCCTLKV+NV  VPPN +QFDFLGKDSIR
Sbjct: 621  TKKQIAVATYLIDKLALRAGNEKDDDEAETVGCCTLKVDNVTCVPPNNLQFDFLGKDSIR 680

Query: 1215 YFNTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVF 1036
            YFNTV VE  VYKAI EF              DDLFDKLDT++LN HLK+LMPGLTAKVF
Sbjct: 681  YFNTVEVELPVYKAIEEF-------RAGKKPGDDLFDKLDTTRLNAHLKDLMPGLTAKVF 733

Query: 1035 RTYNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEK 856
            RTYNASITLD +L+KET DGT+ EKIAVYQ ANKEVAIICNHQRSVSK+HD+QM+RLNEK
Sbjct: 734  RTYNASITLDDILHKETEDGTLLEKIAVYQRANKEVAIICNHQRSVSKSHDSQMTRLNEK 793

Query: 855  IEELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKK 676
            I+ELKAQR+ELK DL + +KGK    D +GKPKRN+AP+A EKK+SQV+ KIEKME+DKK
Sbjct: 794  IDELKAQRDELKADLSKVKKGKSLGYDKDGKPKRNLAPEAFEKKISQVETKIEKMEMDKK 853

Query: 675  IKDDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            IK+DLKTVALGTSKINYLDPRITVAWCKR+EVPIEKIFNKSL+AKF+WAMD DP FRF
Sbjct: 854  IKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLIAKFSWAMDVDPDFRF 911


>ONK79065.1 uncharacterized protein A4U43_C01F2540 [Asparagus officinalis]
          Length = 852

 Score =  929 bits (2402), Expect = 0.0
 Identities = 505/856 (58%), Positives = 582/856 (67%), Gaps = 17/856 (1%)
 Frame = -3

Query: 3018 TSFKPSQVDLASSSRKSEGVSNQQKVSMNKPSSKTAELEDSDDEKPLSFRLAGTPLGINK 2839
            T+ K S ++ A     S+     ++  ++  + +   ++ ++   P + R+    L    
Sbjct: 31   TTSKQSHLNSALKKSLSQKHEETRERPVSSHNVRNGNVQKTNSLNPATARVVKHSLEHKA 90

Query: 2838 ESRTPLMKIKPEDATSDDSDDEKPLSFRIPASGSGASQNSLNLKKKLTXXXXXXXXXXXX 2659
             +     K + +   SDDS+D  PLS + P+S SGA Q S                    
Sbjct: 91   GNENVDNKSRVKREVSDDSEDGLPLSAKFPSS-SGAVQRS-------------------- 129

Query: 2658 XXXXXXXXXXXXXXXXXXXSLGATKNESPDSDDDDKPLAARFQQNG--YSKNGSQISRHL 2485
                               S  AT  +S    +D+KPL++R         K+GS+     
Sbjct: 130  ---NPSPMPTSTTSQKIKESTAATTGDS----EDEKPLSSRLPSKSSVIKKSGSEKKPLA 182

Query: 2484 LSGS--------------GKRPSTSADKSALAANKKPKFSEGISQNKVKPEHSXXXXXXX 2347
             +GS               KRP    + S  +++KK K S      KVK E         
Sbjct: 183  SNGSKRTESSDIKPKIVLNKRPPADMNHSIESSSKKAKLSNAPVPGKVKTEAVLKKEKED 242

Query: 2346 XD-YVPISQRLXXXXXXXXXXXXXXKVLNKVVXXXXXXXXXXXXXXXXXXXXXXSTVPPG 2170
             + ++PISQR+               V  K+                         VPPG
Sbjct: 243  DNDHIPISQRIKKSVPSSSQLSTKT-VTKKIAYSFKKDKKMMKKTMKNSKYSKNLKVPPG 301

Query: 2169 SGEGQKWTTLEHSGVIFPPAYKPHGVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKK 1990
            SG GQKWTTLEH+GVIFPP YKPHGVKMLY+G+PV+LTPEQEEVATMFAVMKDTDYA K 
Sbjct: 302  SGGGQKWTTLEHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKP 361

Query: 1989 TFITNFWNDWKEILGENHVIKDFAQCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXX 1810
            TFI NF  DW  ILG+NH+IK F  CDFTPIYEWHLKEKEKKKQM++             
Sbjct: 362  TFIKNFMEDWGRILGKNHIIKKFELCDFTPIYEWHLKEKEKKKQMTSEEKKALKEEKLKQ 421

Query: 1809 XXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPE 1630
              KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK RI P DITINIGK  P+PE
Sbjct: 422  EEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKSRIRPKDITINIGKDAPVPE 481

Query: 1629 CPIPGERWKEIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKD 1450
            CPIPG+RWKEI+HDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LKD
Sbjct: 482  CPIPGQRWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKD 541

Query: 1449 YIQTIRANYTKDFTSKDESRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVA 1270
            YI+ IRA YTKDFTSKD ++RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 
Sbjct: 542  YIEGIRATYTKDFTSKDPTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVT 601

Query: 1269 LVPPNQIQFDFLGKDSIRYFNTVVVEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTS 1090
             VPPN++QFDFLGKDSIRYFNTV VE  VYKAIG+F              DDLFD LDTS
Sbjct: 602  CVPPNKLQFDFLGKDSIRYFNTVEVELPVYKAIGDFQTVTKSNGKKKAGGDDLFDMLDTS 661

Query: 1089 KLNTHLKELMPGLTAKVFRTYNASITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNH 910
            KLN HLKELMPGLTAKVFRTYNASITLD ML +ET++GT+ EKIA+YQ ANKEVAIICNH
Sbjct: 662  KLNAHLKELMPGLTAKVFRTYNASITLDSMLFEETKEGTLPEKIAIYQHANKEVAIICNH 721

Query: 909  QRSVSKTHDAQMSRLNEKIEELKAQREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALE 730
            QRSVSK+HDAQMSRLNEKI+ELKAQ+EEL+ DL RARKGKP LK      K+N++P+ LE
Sbjct: 722  QRSVSKSHDAQMSRLNEKIDELKAQKEELQVDLSRARKGKPTLKQ-----KKNLSPEVLE 776

Query: 729  KKLSQVDAKIEKMELDKKIKDDLKTVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSL 550
            KKL+QV+AKIEKME+DKK+K+DLKTVALGTSKINYLDPRI+VAWCKR EVPIEKIFNKSL
Sbjct: 777  KKLNQVEAKIEKMEIDKKVKEDLKTVALGTSKINYLDPRISVAWCKRNEVPIEKIFNKSL 836

Query: 549  LAKFTWAMDADPSFRF 502
            LAKF+WAMD DP +RF
Sbjct: 837  LAKFSWAMDVDPDYRF 852


>NP_001157806.2 topoisomerase I [Zea mays] AQK50787.1 DNA topoisomerase 1 beta [Zea
            mays] AQK50788.1 DNA topoisomerase 1 beta [Zea mays]
            AQK50791.1 DNA topoisomerase 1 beta [Zea mays] AQK50793.1
            DNA topoisomerase 1 beta [Zea mays] AQK50804.1 DNA
            topoisomerase 1 beta [Zea mays]
          Length = 904

 Score =  929 bits (2401), Expect = 0.0
 Identities = 498/892 (55%), Positives = 608/892 (68%), Gaps = 22/892 (2%)
 Frame = -3

Query: 3111 PNPSLVKCPASQVSPNCENTYSRRNKVVSVATSFKPSQVDLASSSRKSE-GVSNQQKVSM 2935
            P+ S    P+    PN    +S +   + ++   +P   D  S     E  +  ++KV  
Sbjct: 77   PSSSPNHRPSGSGQPNSLAQHSSKANSIDMSKLKRPLVKDERSDDSDDEVPIGLRRKVEE 136

Query: 2934 NK---PSSKTAELEDSDDE-KPLSFRLAGTPLGINKESRTPLMKIKPE-DATSDDSDDEK 2770
             K     ++  + +DSDD+ KPL  ++  + +  N+ ++  L +  P+ +   +DSDD+K
Sbjct: 137  KKLKGVDTRVQKTDDSDDDDKPLGLKINSSRMSSNRVNKPVLQRTVPKVEQPDEDSDDDK 196

Query: 2769 PLSFRIPASGSGASQNSLNLKKKLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGA 2590
            PL+ R+P++    S   ++                                         
Sbjct: 197  PLASRLPSNAGPKSGGDVS----------------------------------------- 215

Query: 2589 TKNESPDSDDDDKPLAARFQQNGYSKNG--SQISRHLLSGS------GKRPSTSADKSAL 2434
                  +  +D+KPLAARF +   S N   +  S+ L S +      GKRP  ++++++ 
Sbjct: 216  ------EDSEDEKPLAARFSKVAGSGNPKIASSSKGLTSDTNGQQSLGKRPLDNSNQTSS 269

Query: 2433 AANK-KPK--FSEGISQNKVKPEHSXXXXXXXXDYVPISQRLXXXXXXXXXXXXXXKVLN 2263
            A  K KP    +  I + ++K + +           P++QRL                  
Sbjct: 270  ALKKAKPSNVSASAIVRREIKTDDN----------TPLAQRLKMGESSKGKSSAKSVFKK 319

Query: 2262 -----KVVXXXXXXXXXXXXXXXXXXXXXXSTVPPGSGEGQKWTTLEHSGVIFPPAYKPH 2098
                 K                          VPPGSG G+KWTTLEH+GVIFPP YKPH
Sbjct: 320  SPASVKKDIKKMKGKGKLKKNMKNSQFSKIMKVPPGSGGGKKWTTLEHNGVIFPPPYKPH 379

Query: 2097 GVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHVIKDFA 1918
            GVKMLY+GKP++LTPEQEEVATMFAVMKDTDYAAK TFI NF+ DW+++LG+NH+IK+F 
Sbjct: 380  GVKMLYNGKPIDLTPEQEEVATMFAVMKDTDYAAKPTFIDNFFTDWRKVLGKNHIIKNFE 439

Query: 1917 QCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPP 1738
             CDFTPIYEWHL+EKE+KKQM+T               KYMWA+VDGVKEKVGNFRVEPP
Sbjct: 440  LCDFTPIYEWHLREKERKKQMTTEEKKTLREDKLKQEEKYMWAVVDGVKEKVGNFRVEPP 499

Query: 1737 GLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTVTWLAFWN 1558
            GLFRGRGEHPKMGKLK+RI P DITINIGKG P+PECPIPGE WKE+KHDNTVTWLAFWN
Sbjct: 500  GLFRGRGEHPKMGKLKRRILPSDITINIGKGAPVPECPIPGESWKEVKHDNTVTWLAFWN 559

Query: 1557 DPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDESRRQIA 1378
            DPINPK+FKYVFLAASSSLKGQSDKEKYEK+RKLK +IQ IR NYTKDF +KD +RRQIA
Sbjct: 560  DPINPKDFKYVFLAASSSLKGQSDKEKYEKSRKLKGHIQRIRENYTKDFKNKDVTRRQIA 619

Query: 1377 VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRYFNTVV 1198
            VATYLIDKLALRAGNEKDDDEADTVGCCTLKV+NV  +PPNQIQFDFLGKDSIRYFNTV 
Sbjct: 620  VATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNVTCMPPNQIQFDFLGKDSIRYFNTVE 679

Query: 1197 VEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRTYNAS 1018
            VE  VYKAI  F               DLFDK+DTS+LN HLK+LMPGLTAKVFRTYNAS
Sbjct: 680  VEELVYKAIEGF-------RAGKKPGQDLFDKIDTSRLNAHLKDLMPGLTAKVFRTYNAS 732

Query: 1017 ITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKIEELKA 838
            ITLD +L++ET DGTV EKIAVYQ ANKEVAIICNHQRSVSK+H++QM+R+NEKI+ELK+
Sbjct: 733  ITLDGILHEETEDGTVLEKIAVYQRANKEVAIICNHQRSVSKSHESQMTRMNEKIDELKS 792

Query: 837  QREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKIKDDLK 658
            Q EELK DL++A+KGKP   D+EGKPKRN+AP+A++KK++ ++ KIEKME+DK+IK+DLK
Sbjct: 793  QMEELKADLNKAKKGKPLGYDSEGKPKRNLAPEAIQKKVATLEGKIEKMEMDKRIKEDLK 852

Query: 657  TVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            TVALGTSKINYLDPRITVAWCKR+EVPIEKIFNKSLLAKF WAMD DP FRF
Sbjct: 853  TVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFVWAMDVDPEFRF 904


>ACS44671.1 DNA topoisomerase I [Zea mays]
          Length = 904

 Score =  928 bits (2399), Expect = 0.0
 Identities = 499/892 (55%), Positives = 607/892 (68%), Gaps = 22/892 (2%)
 Frame = -3

Query: 3111 PNPSLVKCPASQVSPNCENTYSRRNKVVSVATSFKPSQVDLASSSRKSE-GVSNQQKVSM 2935
            P+ S    P+    PN    +S +   + ++   +P   D  S     E  +  ++KV  
Sbjct: 77   PSSSPNHRPSGSGQPNSLAQHSSKANSIDMSKLKRPLVKDERSDDSDDEVPIGLRRKVEE 136

Query: 2934 NK---PSSKTAELEDSDDE-KPLSFRLAGTPLGINKESRTPLMKIKPE-DATSDDSDDEK 2770
             K     ++  + +DSDD+ KPL  ++  + +  N+ ++  L +  P+ +   +DSDD+K
Sbjct: 137  KKLKGVDTRVQKTDDSDDDDKPLGLKINSSRMSSNRVNKPVLQRTVPKVEQPDEDSDDDK 196

Query: 2769 PLSFRIPASGSGASQNSLNLKKKLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGA 2590
            PL+ R+P++    S   ++                                         
Sbjct: 197  PLASRLPSNAGPKSGGDVS----------------------------------------- 215

Query: 2589 TKNESPDSDDDDKPLAARFQQNGYSKNG--SQISRHLLSGS------GKRPSTSADKSAL 2434
                  +  +D+KPLAARF +   S N   +  S+ L S +      GKRP  S+++++ 
Sbjct: 216  ------EDSEDEKPLAARFSKVAGSGNPKIASSSKGLTSDTNGQQSLGKRPLDSSNQTSS 269

Query: 2433 AANK-KPK--FSEGISQNKVKPEHSXXXXXXXXDYVPISQRLXXXXXXXXXXXXXXKVLN 2263
            A  K KP    +  I + ++K + +           P++QRL                  
Sbjct: 270  ALKKAKPSNVSASAIVRREIKTDDN----------TPLAQRLKMGESSKGKSSAKSVFKK 319

Query: 2262 KVVXXXXXXXXXXXXXXXXXXXXXXS-----TVPPGSGEGQKWTTLEHSGVIFPPAYKPH 2098
              V                             VPPGSG G+KWTTLEH+GVIFPP YKPH
Sbjct: 320  SPVSVKKDIKKMKGKGKLKKNMKNSQFSKIMKVPPGSGGGKKWTTLEHNGVIFPPPYKPH 379

Query: 2097 GVKMLYDGKPVNLTPEQEEVATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHVIKDFA 1918
            GVKMLY+GKPV+LTPEQEEVATMFAVMKDTDYAAK TFI NF+ DW+++LG+NH+IK+F 
Sbjct: 380  GVKMLYNGKPVDLTPEQEEVATMFAVMKDTDYAAKPTFIDNFFTDWRKVLGKNHIIKNFE 439

Query: 1917 QCDFTPIYEWHLKEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPP 1738
             CDFTPIYEWHL+EKE+KKQM+T               KYMWA+VDGVKEKVGNFRVEPP
Sbjct: 440  LCDFTPIYEWHLREKERKKQMTTEEKKTLREDNLKQEEKYMWAVVDGVKEKVGNFRVEPP 499

Query: 1737 GLFRGRGEHPKMGKLKKRIYPHDITINIGKGVPIPECPIPGERWKEIKHDNTVTWLAFWN 1558
            GLFRGRGEHPKMGKLK+RI P DITINIGKG P+PECPIPGE WKE+KHDNTVTWLAFWN
Sbjct: 500  GLFRGRGEHPKMGKLKRRILPSDITINIGKGAPVPECPIPGESWKEVKHDNTVTWLAFWN 559

Query: 1557 DPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDESRRQIA 1378
            DPINPK+FKYVFLAASSSLKGQSDKEKYEK+RKLK +IQ IR NYTKDF +KD +RRQIA
Sbjct: 560  DPINPKDFKYVFLAASSSLKGQSDKEKYEKSRKLKGHIQRIRENYTKDFKNKDVTRRQIA 619

Query: 1377 VATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRYFNTVV 1198
            VATYLIDKLALRAGNEKDDDEADTVGCCTLKV+NV  +PPNQIQFDFLGKDSIRYFNTV 
Sbjct: 620  VATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNVTCMPPNQIQFDFLGKDSIRYFNTVE 679

Query: 1197 VEPAVYKAIGEFXXXXXXXXXXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRTYNAS 1018
            VE  VYKAI  F               DLFDK+DTS+LN HLK+LMPGLTAKVFRTYNAS
Sbjct: 680  VEELVYKAIEGF-------RAGKKPGQDLFDKIDTSRLNAHLKDLMPGLTAKVFRTYNAS 732

Query: 1017 ITLDQMLNKETRDGTVQEKIAVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKIEELKA 838
            ITLD +L++ET DGTV EKIAVYQ ANKEVAIICN QRSVSK+H++QM+R+NEKI+ELK+
Sbjct: 733  ITLDGILHEETEDGTVLEKIAVYQRANKEVAIICNQQRSVSKSHESQMTRMNEKIDELKS 792

Query: 837  QREELKEDLHRARKGKPPLKDAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKIKDDLK 658
            Q EELK DL++A+KGKP   D+EGKPKRN+AP+A++KK++ ++ KIEKME+DK+IK+DLK
Sbjct: 793  QMEELKADLNKAKKGKPLGYDSEGKPKRNLAPEAIQKKVATLEGKIEKMEMDKRIKEDLK 852

Query: 657  TVALGTSKINYLDPRITVAWCKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            TVALGTSKINYLDPRITVAWCKR+EVPIEKIFNKSLLAKF WAMD DP FRF
Sbjct: 853  TVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFVWAMDVDPEFRF 904


>XP_016720339.1 PREDICTED: DNA topoisomerase 1-like [Gossypium hirsutum]
            XP_016720340.1 PREDICTED: DNA topoisomerase 1-like
            [Gossypium hirsutum] XP_016720342.1 PREDICTED: DNA
            topoisomerase 1-like [Gossypium hirsutum]
          Length = 897

 Score =  928 bits (2398), Expect = 0.0
 Identities = 509/872 (58%), Positives = 585/872 (67%), Gaps = 14/872 (1%)
 Frame = -3

Query: 3075 VSPNCENTYSRRNKVVS--VATSFKPSQVDLASSSRKSEGVSNQQKVSMNKPSSKTAELE 2902
            +SP   N+ S+ + VVS   +TSF   Q   AS   K   V  ++  S  K + +T   +
Sbjct: 89   LSPKSSNSSSKASPVVSSKASTSFN-DQSKQASKQNKFTAVKEEK--SPIKCTDETNS-D 144

Query: 2901 DSDDEKPLSFRLAGTPLGINKESRT----------PLMKIKPEDATSDDSDDEKPLSFRI 2752
            D DD KPLS RL G     NK   T          P +++K    +++D DD+ PLS R 
Sbjct: 145  DDDDSKPLSARLKGISSQGNKGVSTSTPAQSQRFVPKIEVK---GSAEDPDDDAPLSARF 201

Query: 2751 PASGSGASQNSLNLKKKLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGATKNESP 2572
                +  + +S                                                P
Sbjct: 202  STKSNTGTSSS-----------------------------------------------KP 214

Query: 2571 DSDDDDKPLAARFQQNGYSKNGSQISRHLLSGSGKRPSTSADKSALAANKKPKFSEGISQ 2392
                + KPLA++ QQNG      Q    +LS   KRP    + S  +  KKPK S+  + 
Sbjct: 215  YGSHEKKPLASKIQQNGSIMKVKQQKSSMLSD--KRPLDKGNSSDQSYAKKPKISDAPTM 272

Query: 2391 NKVKPEHSXXXXXXXXDYVPISQRLXXXXXXXXXXXXXXKVLNKVVXXXXXXXXXXXXXX 2212
             K K            D++PISQR+              +   KVV              
Sbjct: 273  MKTKQVTVKAEKDDEDDHIPISQRIKKSVSSVSKASSVKQKATKVVSSSFKKINKKSKKD 332

Query: 2211 XXXXXXXXST-VPPGSGEGQK-WTTLEHSGVIFPPAYKPHGVKMLYDGKPVNLTPEQEEV 2038
                    ST + P SG+GQK W+TL H+GVIFPP YKPHGVKMLYDG+PV+LTPEQEEV
Sbjct: 333  MKNSKYSKSTKLSPSSGDGQKKWSTLVHNGVIFPPPYKPHGVKMLYDGRPVDLTPEQEEV 392

Query: 2037 ATMFAVMKDTDYAAKKTFITNFWNDWKEILGENHVIKDFAQCDFTPIYEWHLKEKEKKKQ 1858
            ATMFAVM++TDY +K  F  NFW DW ++LG NHVIK   +CDFTPIYEWHL+EKEKKKQ
Sbjct: 393  ATMFAVMQETDYMSKPQFKKNFWEDWSKLLGRNHVIKSLDKCDFTPIYEWHLQEKEKKKQ 452

Query: 1857 MSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIY 1678
            MS+               KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI 
Sbjct: 453  MSSEEKKALKEEKLMQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIR 512

Query: 1677 PHDITINIGKGVPIPECPIPGERWKEIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLK 1498
            P DITINIGK  PIPECPIPGERWK+IKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLK
Sbjct: 513  PCDITINIGKDAPIPECPIPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLK 572

Query: 1497 GQSDKEKYEKARKLKDYIQTIRANYTKDFTSKDESRRQIAVATYLIDKLALRAGNEKDDD 1318
            GQSDKEKYEKAR LKDYI+ IRA YTKDFT+KD ++RQIAVATYLIDKLALRAGNEKDDD
Sbjct: 573  GQSDKEKYEKARLLKDYIKNIRAAYTKDFTAKDVTKRQIAVATYLIDKLALRAGNEKDDD 632

Query: 1317 EADTVGCCTLKVENVALVPPNQIQFDFLGKDSIRYFNTVVVEPAVYKAIGEFXXXXXXXX 1138
            EADTVGCCTLKV NV  +PPN+++FDFLGKDSI+Y NTV VE  VYKAIG+F        
Sbjct: 633  EADTVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQF-------Q 685

Query: 1137 XXXXNSDDLFDKLDTSKLNTHLKELMPGLTAKVFRTYNASITLDQMLNKETRDGTVQEKI 958
                 SDDLFD+LDTSKLN HLKELMPGLTAKVFRTYNASITLD MLNKET+DG V EK+
Sbjct: 686  TGKSKSDDLFDELDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLNKETKDGDVAEKV 745

Query: 957  AVYQTANKEVAIICNHQRSVSKTHDAQMSRLNEKIEELKAQREELKEDLHRARKGKPPLK 778
             +YQ ANKEVAIICNHQRS+SK+H AQMSRL EKI ELK   +ELK DL RA+KGKPPLK
Sbjct: 746  VIYQRANKEVAIICNHQRSISKSHSAQMSRLTEKITELKGLLKELKTDLDRAKKGKPPLK 805

Query: 777  DAEGKPKRNMAPDALEKKLSQVDAKIEKMELDKKIKDDLKTVALGTSKINYLDPRITVAW 598
            DA+GK KRN+ P+A+EKK++Q + KIEKME D + K+DLKTVALGTSKINYLDPRITVAW
Sbjct: 806  DADGKQKRNLTPEAIEKKIAQTNVKIEKMERDMQTKEDLKTVALGTSKINYLDPRITVAW 865

Query: 597  CKRYEVPIEKIFNKSLLAKFTWAMDADPSFRF 502
            CKR+EVPIEKIFNKSLLAKF WAMD DP FRF
Sbjct: 866  CKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF 897