BLASTX nr result
ID: Akebia27_contig00006487
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Akebia27_contig00006487
(1121 letters)
Database: ./nr
38,876,450 sequences; 13,856,398,315 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|EXB52898.1| Calcium-dependent protein kinase 8 [Morus notabilis] 173 1e-40
ref|XP_002513496.1| calcium-dependent protein kinase, putative [... 173 1e-40
ref|XP_002322709.1| calcium-dependent protein kinase [Populus tr... 173 1e-40
gb|AEI70328.1| calcium-dependent protein kinase [Hevea brasilien... 171 4e-40
gb|AFR11232.1| calcium dependent protein kinase 3 [Chenopodium a... 170 9e-40
gb|EYU18750.1| hypothetical protein MIMGU_mgv1a004372mg [Mimulus... 169 1e-39
gb|AGI21023.1| calcium-dependent protein kinase 3 [Dendrobium of... 169 1e-39
ref|XP_004150764.1| PREDICTED: calcium-dependent protein kinase ... 169 1e-39
gb|EYU31372.1| hypothetical protein MIMGU_mgv1a004319mg [Mimulus... 169 2e-39
ref|XP_006366539.1| PREDICTED: calcium-dependent protein kinase ... 169 2e-39
ref|XP_007028795.1| Calcium-dependent protein kinase 19 [Theobro... 168 4e-39
ref|NP_001060031.1| Os07g0568600 [Oryza sativa Japonica Group] g... 168 4e-39
dbj|BAJ96261.1| predicted protein [Hordeum vulgare subsp. vulgare] 168 4e-39
ref|NP_001147084.1| LOC100280693 [Zea mays] gi|195607124|gb|ACG2... 168 4e-39
gb|EAZ04388.1| hypothetical protein OsI_26532 [Oryza sativa Indi... 168 4e-39
ref|XP_006657859.1| PREDICTED: calcium-dependent protein kinase ... 167 6e-39
ref|XP_006489930.1| PREDICTED: calcium-dependent protein kinase ... 167 6e-39
ref|XP_006489929.1| PREDICTED: calcium-dependent protein kinase ... 167 6e-39
ref|XP_006421421.1| hypothetical protein CICLE_v10004707mg [Citr... 167 6e-39
ref|XP_004958070.1| PREDICTED: calcium-dependent protein kinase ... 167 6e-39
>gb|EXB52898.1| Calcium-dependent protein kinase 8 [Morus notabilis]
Length = 530
Score = 173 bits (439), Expect = 1e-40
Identities = 81/103 (78%), Positives = 95/103 (92%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGND++HLHKAF FFD+N++GYIEI+ELR ADE++ NNE+VINAI +DVDTDKDGRI
Sbjct: 424 KMGNDEEHLHKAFEFFDKNQTGYIEIEELRHALADEVEDNNEEVINAIMQDVDTDKDGRI 483
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQVN 813
SYEEFA MMKAGTDWRKASRQYSRE FNSLSL+LMK+GSLQ++
Sbjct: 484 SYEEFATMMKAGTDWRKASRQYSRELFNSLSLRLMKEGSLQLD 526
>ref|XP_002513496.1| calcium-dependent protein kinase, putative [Ricinus communis]
gi|223547404|gb|EEF48899.1| calcium-dependent protein
kinase, putative [Ricinus communis]
Length = 536
Score = 173 bits (438), Expect = 1e-40
Identities = 85/102 (83%), Positives = 93/102 (91%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGND+ H+HKAFAFFDQN+SGYIEI+ELR+ DE+D +EDVINAI DVDTDKDGRI
Sbjct: 434 KMGNDE-HIHKAFAFFDQNQSGYIEIEELREALNDEVDTCSEDVINAIMHDVDTDKDGRI 492
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SYEEFA MMKAGTDWRKASRQYSRERFNSLSLKLM+DGSLQV
Sbjct: 493 SYEEFATMMKAGTDWRKASRQYSRERFNSLSLKLMRDGSLQV 534
>ref|XP_002322709.1| calcium-dependent protein kinase [Populus trichocarpa]
gi|222867339|gb|EEF04470.1| calcium-dependent protein
kinase [Populus trichocarpa]
Length = 532
Score = 173 bits (438), Expect = 1e-40
Identities = 85/102 (83%), Positives = 94/102 (92%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGND+ HL KAF FFDQN+SG+IEIDELRD ADE+D +NEDVINAI DVDTDKDG+I
Sbjct: 427 KMGNDE-HLRKAFEFFDQNQSGHIEIDELRDALADEVDGSNEDVINAIIHDVDTDKDGKI 485
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SYEEFAAMMKAGTDWRKASRQYSRERFN+LSLKLMKDGSL++
Sbjct: 486 SYEEFAAMMKAGTDWRKASRQYSRERFNNLSLKLMKDGSLKL 527
>gb|AEI70328.1| calcium-dependent protein kinase [Hevea brasiliensis]
Length = 530
Score = 171 bits (434), Expect = 4e-40
Identities = 83/103 (80%), Positives = 94/103 (91%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGND+ HL KAF FFD+N+SGYIEI+ELRD ADE+D N+E++INAI DVDTDKDGRI
Sbjct: 426 KMGNDE-HLLKAFEFFDKNQSGYIEIEELRDALADEVDENSEEIINAIIHDVDTDKDGRI 484
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQVN 813
SY+EFA MMKAGTDWRKASRQYSRERFN+LSLKLMKDGSLQ+N
Sbjct: 485 SYDEFATMMKAGTDWRKASRQYSRERFNNLSLKLMKDGSLQMN 527
>gb|AFR11232.1| calcium dependent protein kinase 3 [Chenopodium album]
Length = 529
Score = 170 bits (431), Expect = 9e-40
Identities = 84/101 (83%), Positives = 93/101 (92%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGND+ HL KAF FFDQN++GYIEI+ELR ADE+D N+E+VINAI RDVDTDKDGRI
Sbjct: 424 KMGNDE-HLQKAFLFFDQNKNGYIEIEELRHSLADELDDNSEEVINAIMRDVDTDKDGRI 482
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQ 819
SYEEFAAMMKAGTDWRKASRQYSRERFN+LSLKL+KDGSLQ
Sbjct: 483 SYEEFAAMMKAGTDWRKASRQYSRERFNNLSLKLIKDGSLQ 523
>gb|EYU18750.1| hypothetical protein MIMGU_mgv1a004372mg [Mimulus guttatus]
Length = 530
Score = 169 bits (429), Expect = 1e-39
Identities = 83/103 (80%), Positives = 94/103 (91%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGNDD HL KAF FFD+NESGYIEI+ELRD FADE + +E+VINAI +DVDTDKDGRI
Sbjct: 426 KMGNDD-HLRKAFQFFDRNESGYIEIEELRDAFADEAEATSEEVINAIIQDVDTDKDGRI 484
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQVN 813
S+EEFAAMMK+GTDWRKASRQYSRER+NSLSLKLM DGSLQ++
Sbjct: 485 SFEEFAAMMKSGTDWRKASRQYSRERYNSLSLKLMTDGSLQMS 527
>gb|AGI21023.1| calcium-dependent protein kinase 3 [Dendrobium officinale]
Length = 536
Score = 169 bits (429), Expect = 1e-39
Identities = 82/102 (80%), Positives = 93/102 (91%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
K+GND+ HLHKAFA+FDQN+SGYIEI+EL D D++ PN E+VINAI RDVDTDKDG+I
Sbjct: 431 KLGNDE-HLHKAFAYFDQNKSGYIEIEELSDALQDDLGPNYEEVINAIIRDVDTDKDGKI 489
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SYEEFAAMMKAGTDWRKASRQYSRERF SLSLKL+KDGSLQ+
Sbjct: 490 SYEEFAAMMKAGTDWRKASRQYSRERFTSLSLKLIKDGSLQL 531
>ref|XP_004150764.1| PREDICTED: calcium-dependent protein kinase 7-like [Cucumis sativus]
gi|449508351|ref|XP_004163290.1| PREDICTED:
calcium-dependent protein kinase 7-like [Cucumis sativus]
Length = 535
Score = 169 bits (429), Expect = 1e-39
Identities = 81/102 (79%), Positives = 92/102 (90%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
+MG+D++HL KAF FFDQN SGYIEI+ELR ADE+D N+E+VINAI DVDTDKDGRI
Sbjct: 432 RMGDDEEHLRKAFDFFDQNLSGYIEIEELRSTLADEIDENSEEVINAIINDVDTDKDGRI 491
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SY+EFAAMMKAGTDWRKASRQYSRERFNSLSL LM+DGSLQ+
Sbjct: 492 SYDEFAAMMKAGTDWRKASRQYSRERFNSLSLNLMRDGSLQL 533
>gb|EYU31372.1| hypothetical protein MIMGU_mgv1a004319mg [Mimulus guttatus]
Length = 533
Score = 169 bits (428), Expect = 2e-39
Identities = 84/102 (82%), Positives = 92/102 (90%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KM ND+ HLHKAFAFFD+NESGYIEIDELRD +DE D N+E+VI AI DVDTDKDGRI
Sbjct: 428 KMANDE-HLHKAFAFFDRNESGYIEIDELRDALSDEDDANSEEVIIAIMHDVDTDKDGRI 486
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SYEEFA+MMKAGTDWRKASRQYSRERFNSLSLKLMK+GSL +
Sbjct: 487 SYEEFASMMKAGTDWRKASRQYSRERFNSLSLKLMKEGSLHL 528
>ref|XP_006366539.1| PREDICTED: calcium-dependent protein kinase 8-like [Solanum
tuberosum]
Length = 533
Score = 169 bits (428), Expect = 2e-39
Identities = 83/102 (81%), Positives = 92/102 (90%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KM ND+ HLHKAF+FFD+N+SGYIEI+ELR +DE D N+E+V NAI DVDTDKDGRI
Sbjct: 429 KMANDE-HLHKAFSFFDKNQSGYIEIEELRSALSDEDDSNSEEVTNAIMHDVDTDKDGRI 487
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLM+DGSLQV
Sbjct: 488 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMRDGSLQV 529
>ref|XP_007028795.1| Calcium-dependent protein kinase 19 [Theobroma cacao]
gi|508717400|gb|EOY09297.1| Calcium-dependent protein
kinase 19 [Theobroma cacao]
Length = 533
Score = 168 bits (425), Expect = 4e-39
Identities = 82/103 (79%), Positives = 94/103 (91%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGND+ HL KAF FFD+N+SG+IEI+ELRD ADE++ N+E+VI+AI DVDTDKDGRI
Sbjct: 428 KMGNDE-HLKKAFEFFDRNQSGFIEIEELRDALADEVETNSEEVISAIMHDVDTDKDGRI 486
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQVN 813
SY+EFAAMMKAGTDWRKASRQYSRERFNSLSLKLM+DGSLQ N
Sbjct: 487 SYDEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMRDGSLQSN 529
>ref|NP_001060031.1| Os07g0568600 [Oryza sativa Japonica Group]
gi|34393291|dbj|BAC83205.1| putative calcium-dependent
protein kinase [Oryza sativa Japonica Group]
gi|113611567|dbj|BAF21945.1| Os07g0568600 [Oryza sativa
Japonica Group] gi|125600773|gb|EAZ40349.1| hypothetical
protein OsJ_24795 [Oryza sativa Japonica Group]
Length = 550
Score = 168 bits (425), Expect = 4e-39
Identities = 81/102 (79%), Positives = 94/102 (92%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
K+GND+ HLHKAFA+FD+N+SGYIEIDELR+ AD++ N+E+VINAI RDVDTDKDG+I
Sbjct: 446 KIGNDE-HLHKAFAYFDRNQSGYIEIDELRESLADDLGANHEEVINAIIRDVDTDKDGKI 504
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SY+EFAAMMKAGTDWRKASRQYSRERF SLSLKL KDGSLQ+
Sbjct: 505 SYDEFAAMMKAGTDWRKASRQYSRERFTSLSLKLQKDGSLQL 546
>dbj|BAJ96261.1| predicted protein [Hordeum vulgare subsp. vulgare]
Length = 545
Score = 168 bits (425), Expect = 4e-39
Identities = 80/102 (78%), Positives = 93/102 (91%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
K+GND+ HLHKAF +FD+N+SGYIEIDELR+ AD++ PN+E+VINAI RDVDTDKDG+I
Sbjct: 441 KIGNDE-HLHKAFGYFDRNKSGYIEIDELRESLADDLGPNHEEVINAIIRDVDTDKDGKI 499
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
S+EEF AMMKAGTDWRKASRQYSRERF SLSLKL KDGSLQ+
Sbjct: 500 SFEEFVAMMKAGTDWRKASRQYSRERFTSLSLKLQKDGSLQI 541
>ref|NP_001147084.1| LOC100280693 [Zea mays] gi|195607124|gb|ACG25392.1| calcium-dependent
protein kinase, isoform AK1 [Zea mays]
gi|223947505|gb|ACN27836.1| unknown [Zea mays]
gi|414590577|tpg|DAA41148.1| TPA: putative
calcium-dependent protein kinase family protein [Zea
mays]
Length = 539
Score = 168 bits (425), Expect = 4e-39
Identities = 81/102 (79%), Positives = 94/102 (92%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
K+GND+ HLHKAFA+FD+N+SGYIEIDELR+ AD++ N+E+VINAI RDVDTDKDG+I
Sbjct: 435 KIGNDE-HLHKAFAYFDRNQSGYIEIDELRESLADDLGQNHEEVINAIIRDVDTDKDGKI 493
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SY+EFAAMMKAGTDWRKASRQYSRERF SLSLKL KDGSLQ+
Sbjct: 494 SYDEFAAMMKAGTDWRKASRQYSRERFTSLSLKLQKDGSLQM 535
>gb|EAZ04388.1| hypothetical protein OsI_26532 [Oryza sativa Indica Group]
Length = 550
Score = 168 bits (425), Expect = 4e-39
Identities = 81/102 (79%), Positives = 94/102 (92%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
K+GND+ HLHKAFA+FD+N+SGYIEIDELR+ AD++ N+E+VINAI RDVDTDKDG+I
Sbjct: 446 KIGNDE-HLHKAFAYFDRNQSGYIEIDELRESLADDLGANHEEVINAIIRDVDTDKDGKI 504
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SY+EFAAMMKAGTDWRKASRQYSRERF SLSLKL KDGSLQ+
Sbjct: 505 SYDEFAAMMKAGTDWRKASRQYSRERFTSLSLKLQKDGSLQL 546
>ref|XP_006657859.1| PREDICTED: calcium-dependent protein kinase 8-like [Oryza
brachyantha]
Length = 552
Score = 167 bits (424), Expect = 6e-39
Identities = 81/102 (79%), Positives = 94/102 (92%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
K+GND+ HLHKAFA+FD+N+SGYIEIDELR+ AD++ N+E+VINAI RDVDTDKDG+I
Sbjct: 448 KIGNDE-HLHKAFAYFDRNKSGYIEIDELRESLADDLGANHEEVINAIIRDVDTDKDGKI 506
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SY+EFAAMMKAGTDWRKASRQYSRERF SLSLKL KDGSLQ+
Sbjct: 507 SYDEFAAMMKAGTDWRKASRQYSRERFTSLSLKLQKDGSLQL 548
>ref|XP_006489930.1| PREDICTED: calcium-dependent protein kinase 32-like isoform X2
[Citrus sinensis]
Length = 532
Score = 167 bits (424), Expect = 6e-39
Identities = 83/103 (80%), Positives = 92/103 (89%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGND+ HLHKAF FFDQN++GYIE++ELRD ADE+D +E+V+ AI DVDTDKDGRI
Sbjct: 428 KMGNDE-HLHKAFQFFDQNQTGYIELEELRDALADEVD-TSEEVVTAIMHDVDTDKDGRI 485
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQVN 813
SYEEFA MMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQ N
Sbjct: 486 SYEEFAVMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQSN 528
>ref|XP_006489929.1| PREDICTED: calcium-dependent protein kinase 32-like isoform X1
[Citrus sinensis]
Length = 536
Score = 167 bits (424), Expect = 6e-39
Identities = 83/103 (80%), Positives = 92/103 (89%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGND+ HLHKAF FFDQN++GYIE++ELRD ADE+D +E+V+ AI DVDTDKDGRI
Sbjct: 432 KMGNDE-HLHKAFQFFDQNQTGYIELEELRDALADEVD-TSEEVVTAIMHDVDTDKDGRI 489
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQVN 813
SYEEFA MMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQ N
Sbjct: 490 SYEEFAVMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQSN 532
>ref|XP_006421421.1| hypothetical protein CICLE_v10004707mg [Citrus clementina]
gi|557523294|gb|ESR34661.1| hypothetical protein
CICLE_v10004707mg [Citrus clementina]
Length = 532
Score = 167 bits (424), Expect = 6e-39
Identities = 83/103 (80%), Positives = 92/103 (89%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
KMGND+ HLHKAF FFDQN++GYIE++ELRD ADE+D +E+V+ AI DVDTDKDGRI
Sbjct: 428 KMGNDE-HLHKAFQFFDQNQTGYIELEELRDALADEVD-TSEEVVTAIMHDVDTDKDGRI 485
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQVN 813
SYEEFA MMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQ N
Sbjct: 486 SYEEFAVMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQSN 528
>ref|XP_004958070.1| PREDICTED: calcium-dependent protein kinase 7-like [Setaria italica]
Length = 541
Score = 167 bits (424), Expect = 6e-39
Identities = 81/102 (79%), Positives = 93/102 (91%)
Frame = -1
Query: 1121 KMGNDDDHLHKAFAFFDQNESGYIEIDELRDVFADEMDPNNEDVINAIFRDVDTDKDGRI 942
K+GND+ HLHKAFA+FD+NESGYIEIDELR+ AD++ N+E+VINAI RDVDTDKDG+I
Sbjct: 437 KIGNDE-HLHKAFAYFDRNESGYIEIDELRESLADDLGQNHEEVINAIIRDVDTDKDGKI 495
Query: 941 SYEEFAAMMKAGTDWRKASRQYSRERFNSLSLKLMKDGSLQV 816
SY+EFA MMKAGTDWRKASRQYSRERF SLSLKL KDGSLQ+
Sbjct: 496 SYDEFATMMKAGTDWRKASRQYSRERFTSLSLKLQKDGSLQM 537