BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Akebia25_contig00019895
         (3115 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis v...  1290   0.0  
emb|CBI24922.3| unnamed protein product [Vitis vinifera]             1233   0.0  
ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cac...  1193   0.0  
ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cac...  1190   0.0  
ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum...  1170   0.0  
ref|XP_006439079.1| hypothetical protein CICLE_v10030505mg [Citr...  1167   0.0  
ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2-like [Citrus ...  1166   0.0  
ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2-like [Solanum...  1162   0.0  
ref|XP_006439078.1| hypothetical protein CICLE_v10030505mg [Citr...  1161   0.0  
ref|XP_002298421.2| DNA topoisomerase family protein [Populus tr...  1157   0.0  
gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984...  1154   0.0  
ref|XP_002314046.2| DNA topoisomerase family protein [Populus tr...  1139   0.0  
ref|XP_007220582.1| hypothetical protein PRUPE_ppa000202mg [Prun...  1137   0.0  
ref|XP_004308680.1| PREDICTED: DNA topoisomerase 2-like [Fragari...  1132   0.0  
ref|XP_006838283.1| hypothetical protein AMTR_s00103p00101630 [A...  1110   0.0  
ref|XP_007009329.1| Topoisomerase II isoform 3 [Theobroma cacao]...  1101   0.0  
gb|EYU27037.1| hypothetical protein MIMGU_mgv1a000169mg [Mimulus...  1086   0.0  
ref|XP_002517802.1| DNA topoisomerase II, putative [Ricinus comm...  1069   0.0  
ref|XP_004149716.1| PREDICTED: DNA topoisomerase 2-like [Cucumis...  1066   0.0  
gb|EXB68160.1| DNA topoisomerase 2 [Morus notabilis]                 1066   0.0  

>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis vinifera]
          Length = 1489

 Score = 1290 bits (3337), Expect = 0.0
 Identities = 671/919 (73%), Positives = 744/919 (80%), Gaps = 12/919 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKAT++NGRV
Sbjct: 521  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHRNGRV 580

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFYSMPEYE WKESLGG  +G SIK  KGLGTSTSKEGKEYFKDL  HKKDF+WVDE+D
Sbjct: 581  LSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEKD 640

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            GDAI+LAFSKKKIE RKNWLRQF+PGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS
Sbjct: 641  GDAIELAFSKKKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 700

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNF+KEAKIAQF+GYVSEHSAYHHGEQSL+STIIGMAQD+VG
Sbjct: 701  MVDGLKPGQRKILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVG 760

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLL PNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDD LLDYLNEDGQSIE
Sbjct: 761  SNNINLLLPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIE 820

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT YVP IP VLVNGSEGIGTGWSS IPNYNPRDI+AN+R LLNGE MEPMDPWY+GF+G
Sbjct: 821  PTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFRG 880

Query: 2033 TIEKT-ATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEP 1857
            TIEKT  TK+    YTV GIIEEVNETTLRI+ELPVR+WTQDYKEFLESIMTGNDKIK+P
Sbjct: 881  TIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKDP 940

Query: 1856 FIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKY 1677
            FIKDY+EHNDDTTVHFEVIMSEENL+MAK EGL++KFKLTT ISTSNMHLFD  G IKKY
Sbjct: 941  FIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKY 1000

Query: 1676 DTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRAD 1497
            +TPEQIL+EFFHLRLEFYEKR                 KVRFILGVVRGEIIVSNRKRAD
Sbjct: 1001 ETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRAD 1060

Query: 1496 LFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIG-GKVRASDYEYLLSMAI 1320
            LF EL +KGFTPFPKK KS+E A+AG  T+D EE E+N++ +  G VRA+DYEYLLSMAI
Sbjct: 1061 LFHELHQKGFTPFPKKSKSVEIAVAG-ATDDTEEAEENTDAVSKGGVRATDYEYLLSMAI 1119

Query: 1319 GSLTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARK 1140
            G+LTLEKVQELCAD+D+L   VD+LK++TPK+LW+ DLDAL+++LDEQDKNDA+AE  RK
Sbjct: 1120 GTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKNDARAEETRK 1179

Query: 1139 ALKGKVMTEAGLKASR-AVKNPRKNNTKKANN-----PPIEATVSSAVEIGNPSEVLKPK 978
             LK +VM+EAG+K SR A KNPRKNN KKANN       ++ + SSA+E+ +  EV+KPK
Sbjct: 1180 QLKSRVMSEAGMKVSRQAPKNPRKNN-KKANNAEPAAETMDVSASSAMEMESVPEVVKPK 1238

Query: 977  GRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEAP----A 810
            GR  PRKAPAKK+E  T                 LAAYNL+SSPD SAAM++E P    A
Sbjct: 1239 GRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAA 1298

Query: 809  RTKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXX 630
            R KEPS+RAAA+K PL++FTEISDDD   +D+     EE    +    G  +P       
Sbjct: 1299 RKKEPSRRAAAQKKPLASFTEISDDD---EDDEDFEVEEVSASDVKKKGGRKPAANA--- 1352

Query: 629  XXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMRA 450
                                         QLL Q L+T+  KP E  GISPEKK+RKMRA
Sbjct: 1353 -----KAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLGISPEKKVRKMRA 1407

Query: 449  SPFNKKSGSVLGRIGTKDK 393
            SPFNKKSGSVLG  G +D+
Sbjct: 1408 SPFNKKSGSVLGSTGEEDE 1426


>emb|CBI24922.3| unnamed protein product [Vitis vinifera]
          Length = 1452

 Score = 1233 bits (3191), Expect = 0.0
 Identities = 650/918 (70%), Positives = 716/918 (77%), Gaps = 11/918 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKAT++NGRV
Sbjct: 521  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHRNGRV 580

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFYSMPEYE WKESLGG  +G SIK  KGLGTSTSKEGKEYFKDL  HKKDF+WVDE+D
Sbjct: 581  LSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKDFMWVDEKD 640

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            GDAI+LAFSKKKIE RKNWLRQF+PGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS
Sbjct: 641  GDAIELAFSKKKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 700

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNF+KEAKIAQF+GYVSEHSAYHHGEQSL+STIIGMAQD+VG
Sbjct: 701  MVDGLKPGQRKILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVG 760

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLL PNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDD LLDYLNEDGQSIE
Sbjct: 761  SNNINLLLPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIE 820

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT YVP IP VLVNGSEGIGTGWSS IPNYNPRDI+AN+R LLNGE MEPMDPWY+GF+G
Sbjct: 821  PTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPWYRGFRG 880

Query: 2033 TIEKT-ATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEP 1857
            TIEKT  TK+    YTV GIIEEVNETTLRI+ELPVR+WTQDYKEFLESIMTGNDKIK+P
Sbjct: 881  TIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGNDKIKDP 940

Query: 1856 FIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKY 1677
            FIKDY+EHNDDTTVHFEVIMSEENL+MAK EGL++KFKLTT ISTSNMHLFD  G IKKY
Sbjct: 941  FIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSNGTIKKY 1000

Query: 1676 DTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRAD 1497
            +TPEQIL+EFFHLRLEFYEKR                 KVRFILGVVRGEIIVSNRKRAD
Sbjct: 1001 ETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVSNRKRAD 1060

Query: 1496 LFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIG 1317
            LF EL +                                     KVRA+DYEYLLSMAIG
Sbjct: 1061 LFHELHQ-------------------------------------KVRATDYEYLLSMAIG 1083

Query: 1316 SLTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKA 1137
            +LTLEKVQELCAD+D+L   VD+LK++TPK+LW+ DLDAL+++LDEQDKNDA+AE  RK 
Sbjct: 1084 TLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKNDARAEETRKQ 1143

Query: 1136 LKGKVMTEAGLKASR-AVKNPRKNNTKKANN-----PPIEATVSSAVEIGNPSEVLKPKG 975
            LK +VM+EAG+K SR A KNPRKNN KKANN       ++ + SSA+E+ +  EV+KPKG
Sbjct: 1144 LKSRVMSEAGMKVSRQAPKNPRKNN-KKANNAEPAAETMDVSASSAMEMESVPEVVKPKG 1202

Query: 974  RGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEAP----AR 807
            R  PRKAPAKK+E  T                 LAAYNL+SSPD SAAM++E P    AR
Sbjct: 1203 RAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVPAAR 1262

Query: 806  TKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXXX 627
             KEPS+RAAA+K PL++FTEISDDD   +D+     EE    +    G  +P        
Sbjct: 1263 KKEPSRRAAAQKKPLASFTEISDDD---EDDEDFEVEEVSASDVKKKGGRKPAANA---- 1315

Query: 626  XXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMRAS 447
                                        QLL Q L+T+  KP E  GISPEKK+RKMRAS
Sbjct: 1316 ----KAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLGISPEKKVRKMRAS 1371

Query: 446  PFNKKSGSVLGRIGTKDK 393
            PFNKKSGSVLG  G +D+
Sbjct: 1372 PFNKKSGSVLGSTGEEDE 1389


>ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
            gi|508726240|gb|EOY18137.1| DNA topoisomerase 2 isoform 1
            [Theobroma cacao]
          Length = 1473

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 627/915 (68%), Positives = 720/915 (78%), Gaps = 12/915 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+PSF+VEFITPIVKAT+K   V
Sbjct: 518  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKTKGV 577

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFYSMPEYE WKESLGG   G SIK  KGLGTSTSKEGK+YFK+LD H+K+FVW DEQD
Sbjct: 578  LSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQD 637

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G+AI+LAFSKKKIEARKNWLRQFEPGT+LDQ +KLIKYS+F+NKELILFSMADLQRSIPS
Sbjct: 638  GEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPS 697

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            M+DGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STI+GMAQD+VG
Sbjct: 698  MIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVG 757

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLL P GQFGTR+QGGKD ASARYI+T LSPITR+LFPKDDDGLLDYLNEDGQSIE
Sbjct: 758  SNNINLLNPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIE 817

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            P  YVPIIP VLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM PWY+GFKG
Sbjct: 818  PIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKG 877

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
             IEKTA+KEAG +YT++GIIEEV+ETTLRITELPVRRWTQDY+EFLESI+TGND    PF
Sbjct: 878  NIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND----PF 933

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            IK++R+++DDTTV FEVI++EEN+++AK EGL+KKFKLTTTISTSNMHLFD KG+IKKYD
Sbjct: 934  IKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYD 993

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            TPEQIL+EFFHLR EFYEKR                 KVRFILGVV+GEIIV+NRKRADL
Sbjct: 994  TPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADL 1053

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
            FLELQ KGFTPFPKK K++E A+AG  T+D EE E+NSEV    ++ASDY+YLLSMAIGS
Sbjct: 1054 FLELQTKGFTPFPKKAKTVEVAVAG-ATDDTEETEENSEVSAKGLQASDYDYLLSMAIGS 1112

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LTLEKVQELCAD+D+L  EV++L+++TPKSLW+KDLD L+ QLDEQDK  AQAE A K +
Sbjct: 1113 LTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDK-AAQAEEAAKLV 1171

Query: 1133 KGKVMTEAGLKASR-AVKNPRKNNTKKANNPPIEATV----SSAVEIGNPSEVLKPKGRG 969
            KG+   EAG +A R A K PRK N K+ N   +  T     SSA+E       +KPKGRG
Sbjct: 1172 KGR--GEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETETAPAAVKPKGRG 1229

Query: 968  GPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSE---APARTKE 798
            G RKA     +K                   LA YNLDSSPD SAAM++E    PA  KE
Sbjct: 1230 GSRKA-----KKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKKE 1284

Query: 797  PSKR-AAAKKPPLSTFTEISDDDGNM---DDEMQMIPEEKKGDNDDSDGDFEPEVEVVXX 630
            PSKR AAA+K P ++ +EIS+  G +   D++++++            G  +P       
Sbjct: 1285 PSKRAAAARKKPATSLSEISESIGEIDINDEDLEVVEVAAAAAPAGKKGGRKPAAN---- 1340

Query: 629  XXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMRA 450
                                        K+   QKL+T+ LKP E++GISPEKK+RKMRA
Sbjct: 1341 --------SKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMRA 1392

Query: 449  SPFNKKSGSVLGRIG 405
            SPFNKKSGSVLGR+G
Sbjct: 1393 SPFNKKSGSVLGRVG 1407


>ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
            gi|508726241|gb|EOY18138.1| DNA topoisomerase 2 isoform 2
            [Theobroma cacao]
          Length = 1285

 Score = 1190 bits (3079), Expect = 0.0
 Identities = 627/916 (68%), Positives = 721/916 (78%), Gaps = 13/916 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+PSF+VEFITPIVKAT+K   V
Sbjct: 329  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKTKGV 388

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFYSMPEYE WKESLGG   G SIK  KGLGTSTSKEGK+YFK+LD H+K+FVW DEQD
Sbjct: 389  LSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQD 448

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G+AI+LAFSKKKIEARKNWLRQFEPGT+LDQ +KLIKYS+F+NKELILFSMADLQRSIPS
Sbjct: 449  GEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPS 508

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            M+DGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STI+GMAQD+VG
Sbjct: 509  MIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVG 568

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLL P GQFGTR+QGGKD ASARYI+T LSPITR+LFPKDDDGLLDYLNEDGQSIE
Sbjct: 569  SNNINLLNPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIE 628

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            P  YVPIIP VLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM PWY+GFKG
Sbjct: 629  PIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKG 688

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
             IEKTA+KEAG +YT++GIIEEV+ETTLRITELPVRRWTQDY+EFLESI+TGND    PF
Sbjct: 689  NIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND----PF 744

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            IK++R+++DDTTV FEVI++EEN+++AK EGL+KKFKLTTTISTSNMHLFD KG+IKKYD
Sbjct: 745  IKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYD 804

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            TPEQIL+EFFHLR EFYEKR                 KVRFILGVV+GEIIV+NRKRADL
Sbjct: 805  TPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADL 864

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
            FLELQ KGFTPFPKK K++E A+AG  T+D EE E+NSEV    ++ASDY+YLLSMAIGS
Sbjct: 865  FLELQTKGFTPFPKKAKTVEVAVAG-ATDDTEETEENSEVSAKGLQASDYDYLLSMAIGS 923

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LTLEKVQELCAD+D+L  EV++L+++TPKSLW+KDLD L+ QLDEQDK  AQAE A K +
Sbjct: 924  LTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDK-AAQAEEAAKLV 982

Query: 1133 KGKVMTEAGLKASR-AVKNPRKNNTKKANNPPIEATV----SSAVEIGNPS-EVLKPKGR 972
            KG+   EAG +A R A K PRK N K+ N   +  T     SSA+E    +   +KPKGR
Sbjct: 983  KGR--GEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETAETAPAAVKPKGR 1040

Query: 971  GGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSE---APARTK 801
            GG RKA     +K                   LA YNLDSSPD SAAM++E    PA  K
Sbjct: 1041 GGSRKA-----KKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVPQVPAGKK 1095

Query: 800  EPSKR-AAAKKPPLSTFTEISDDDGNM---DDEMQMIPEEKKGDNDDSDGDFEPEVEVVX 633
            EPSKR AAA+K P ++ +EIS+  G +   D++++++            G  +P      
Sbjct: 1096 EPSKRAAAARKKPATSLSEISESIGEIDINDEDLEVVEVAAAAAPAGKKGGRKPAAN--- 1152

Query: 632  XXXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMR 453
                                         K+   QKL+T+ LKP E++GISPEKK+RKMR
Sbjct: 1153 ---------SKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGISPEKKVRKMR 1203

Query: 452  ASPFNKKSGSVLGRIG 405
            ASPFNKKSGSVLGR+G
Sbjct: 1204 ASPFNKKSGSVLGRVG 1219


>ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum tuberosum]
          Length = 1485

 Score = 1170 bits (3028), Expect = 0.0
 Identities = 604/908 (66%), Positives = 710/908 (78%), Gaps = 7/908 (0%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+PSFLVEFITPIVKAT+K+GR+
Sbjct: 518  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFLVEFITPIVKATHKSGRI 577

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            L+FY+MPEYE W+ SLG T++G SIK  KGLGTSTSKEGKEYF+DL  H+KDF+W D QD
Sbjct: 578  LAFYTMPEYEAWRRSLGATSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQD 637

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G++I+LAFSKKKIEARKNWLRQFEPGT+LDQKEK I Y++FVNKELILFSMADLQRSIPS
Sbjct: 638  GESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPS 697

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            M+DGLKPGQRKILFC+FKRNFVKEAK++QF+GYVSEHSAYHHGEQSLSSTIIGMAQDYVG
Sbjct: 698  MLDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 757

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNN+NLLQPNGQFGTR+ GGKDHAS+RYIYTRLSPI RFLFPKDDD +LDYLNEDGQSIE
Sbjct: 758  SNNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKDDDTVLDYLNEDGQSIE 817

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT Y+PIIP VLVNGSEGIGTGWSSY+PNYNPRD+VAN+R LLN E MEPMDPWYKGFKG
Sbjct: 818  PTWYIPIIPMVLVNGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDELMEPMDPWYKGFKG 877

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
            TIEKTATKE GA+YTV+GIIEE +ETTLRI+ELPVRRWT+DYK+FLES+    DK K+ F
Sbjct: 878  TIEKTATKETGATYTVTGIIEEFSETTLRISELPVRRWTEDYKQFLESMTVSTDKSKDAF 937

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            IK+ R + D+ +V FEVIMSEENL++A+ EGL+KKFKLTTTISTSNMHLFD KG IKKYD
Sbjct: 938  IKEVRAYGDENSVCFEVIMSEENLLLAQQEGLLKKFKLTTTISTSNMHLFDSKGKIKKYD 997

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
             PE+IL+EF+H+RLE+YEKR                 KVRFILGVV+GEIIV+NRKRADL
Sbjct: 998  APEEILEEFYHVRLEYYEKRKKTLLEILELELLRIENKVRFILGVVKGEIIVNNRKRADL 1057

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
             LEL+ KGFTPFPKK K +EA +A  +T+DAE++E++ E     VRASDY+YLLSMAIG+
Sbjct: 1058 LLELKNKGFTPFPKK-KPVEAVVAD-STDDAEDSEESPEESNKGVRASDYDYLLSMAIGT 1115

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LTLEKVQELCAD+D+L  EV++++ +TPK LWMKDLD LDKQLDEQDK D Q E AR+ L
Sbjct: 1116 LTLEKVQELCADRDKLNAEVEDMRNATPKDLWMKDLDVLDKQLDEQDKLDIQTEEAREKL 1175

Query: 1133 KGKVMTEAGLKASRAVKNPRKNNTKKA-----NNPPIEATVSSAVEIGNPSEVLKPKGR- 972
            K KVM  AG    +A K   +  TKKA        P++ +V S  E  N +EV KPKGR 
Sbjct: 1176 KKKVMNAAG----KAPKPKPRKTTKKAAVVESTAEPMDVSVGSMAETANVTEVAKPKGRG 1231

Query: 971  GGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEAP-ARTKEP 795
            GG +KAPAK   K                   LAAYNL+SSPD+S   ++EAP A+TK P
Sbjct: 1232 GGSKKAPAK--AKPVVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEAPKAQTKAP 1289

Query: 794  SKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXXXXXXX 615
            +KRAAA+K  L +  ++S+     +DE+++            D +F PEV V        
Sbjct: 1290 AKRAAAQKKALPSTPDVSEG----EDEIEI----------SDDNEFAPEVAVGGKKKGGR 1335

Query: 614  XXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMRASPFNK 435
                                    Q + Q+LIT  LKP E+AG+SP++K+RKMR SPFNK
Sbjct: 1336 KPAAAKAAAAPKPPKKRAPANKQSQSVGQRLITQVLKPAEDAGVSPDRKVRKMRESPFNK 1395

Query: 434  KSGSVLGR 411
            KSG+V+GR
Sbjct: 1396 KSGAVMGR 1403


>ref|XP_006439079.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
            gi|557541275|gb|ESR52319.1| hypothetical protein
            CICLE_v10030505mg [Citrus clementina]
          Length = 1456

 Score = 1167 bits (3020), Expect = 0.0
 Identities = 617/916 (67%), Positives = 717/916 (78%), Gaps = 12/916 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNG+V
Sbjct: 517  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGKV 576

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFYSMP+YE WKESLGG  +  SIK  KGLGTSTSKEGKEYF+++ LHKKDFVW D+QD
Sbjct: 577  LSFYSMPDYEAWKESLGGNASSWSIKYYKGLGTSTSKEGKEYFQNITLHKKDFVWEDDQD 636

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G+AI+LAFSKKKIEARK WL QFEPG +LDQKEK IKYSDFVNKELILFSMADLQRSIPS
Sbjct: 637  GEAIELAFSKKKIEARKKWLLQFEPGNHLDQKEKYIKYSDFVNKELILFSMADLQRSIPS 696

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNF+KEAK+AQF+GYVSEHSAYHHGEQSL+STI+GMAQD+VG
Sbjct: 697  MVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTILGMAQDFVG 756

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLLQPNGQFGTR+QGGKD ASARYI+TRLSPITRFLFPKDDD LLDYLNEDGQ IE
Sbjct: 757  SNNINLLQPNGQFGTRNQGGKDAASARYIFTRLSPITRFLFPKDDDKLLDYLNEDGQQIE 816

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT Y+PIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM PWY+GF+G
Sbjct: 817  PTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMHPWYRGFRG 876

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
            TIEKTA+KEAG +YTV+GIIEEVNETTLRI ELP+RRWTQDY+EFLESI+  ND     F
Sbjct: 877  TIEKTASKEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDS----F 932

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            I+ +R+++DDTTV FEV +SEE+++  K EGL+KKFKLTTTISTSNMHLFD KGVIKKYD
Sbjct: 933  IRGFRQYSDDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYD 992

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            TPEQIL+EFFH+RLEFYEKR                 KVRFILGVV GEI+V+NRKR DL
Sbjct: 993  TPEQILEEFFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTDL 1052

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
             LEL++KGFTPFPK  KSIEA +AG  T++ EE+E+N EV+ G V++ DY+YLLSMAIG+
Sbjct: 1053 LLELRQKGFTPFPKNSKSIEAVVAG-ATDETEESEENPEVVNG-VQSIDYDYLLSMAIGT 1110

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LTLEKVQ L AD+D+L  EVD+L+++TP+SLW+KDLDALD QLDE DK+DA+AE  R  +
Sbjct: 1111 LTLEKVQGLLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLDELDKSDARAEEERMKI 1170

Query: 1133 KGKVMTEAGLK--ASRAVKNPRKNNTKKANNPPIEATVSSAV-EIGNPSEVLKPKGRGGP 963
            KG   ++AG K  A RA KN RKN+ KK+NN    A  + A+ E+ N ++V+KPKGR G 
Sbjct: 1171 KGNGNSDAGPKIVAKRAPKNARKND-KKSNN----ARATEAMGEMDNVTKVVKPKGRAGL 1225

Query: 962  RKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSE---APARTKEPS 792
            +KAPA+K +                    LA+  L+ SPDQS  M++E    PA+ KEPS
Sbjct: 1226 KKAPAEKLDDEEEDEVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEKVQVPAKKKEPS 1285

Query: 791  KRAAAKKPPLSTFTEISDDDGNMDDEMQM---IPEEKKGDNDDSDGD---FEPEVEVVXX 630
            KR AA+K  ++  T  S+D+  +DD+       PE  K     + G+    +P VE    
Sbjct: 1286 KRTAAQKKAVTVETSDSEDEIIIDDDEAFEIAAPEAGKKGGRKAAGNTKAAKPAVET--- 1342

Query: 629  XXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMRA 450
                                        +  L Q+L+T+ LKP E+   SPEKK+RKMRA
Sbjct: 1343 -----------------KKRGPAKKQQPEASLGQRLLTEMLKPTES---SPEKKVRKMRA 1382

Query: 449  SPFNKKSGSVLGRIGT 402
            SPFNKKSGS+LGR GT
Sbjct: 1383 SPFNKKSGSMLGRAGT 1398


>ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2-like [Citrus sinensis]
          Length = 1456

 Score = 1166 bits (3016), Expect = 0.0
 Identities = 616/916 (67%), Positives = 716/916 (78%), Gaps = 12/916 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNG+V
Sbjct: 517  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGKV 576

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFYSMP+YE WKESLGG  +  SIK  KGLGTSTSKEGKEYF+++ LHKKDFVW D+QD
Sbjct: 577  LSFYSMPDYEAWKESLGGNASSWSIKYYKGLGTSTSKEGKEYFQNITLHKKDFVWEDDQD 636

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G+AI+LAFSKKKIEARK WL QFEPG +LDQKEK IKYSDFVNKELILFSMADLQRSIPS
Sbjct: 637  GEAIELAFSKKKIEARKKWLLQFEPGNHLDQKEKYIKYSDFVNKELILFSMADLQRSIPS 696

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNF+KEAK+AQF+GYVSEHSAYHHGEQSL+STI+GMAQD+VG
Sbjct: 697  MVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTILGMAQDFVG 756

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLLQPNGQFGTR+QGGKD ASARYI+TRLSPITRFLFPKDDD LLDYLNEDGQ IE
Sbjct: 757  SNNINLLQPNGQFGTRNQGGKDAASARYIFTRLSPITRFLFPKDDDKLLDYLNEDGQQIE 816

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT Y+PIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM PWY+GF+G
Sbjct: 817  PTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMHPWYRGFRG 876

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
            TIEKTA+KEAG +YTV+GIIEEVNETTLRI ELP+RRWTQDY+EFLESI+  ND     F
Sbjct: 877  TIEKTASKEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDS----F 932

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            I+ +R+++DDTTV FEV +SEE+++  K EGL+KKFKLTTTISTSNMHLFD KGVIKKYD
Sbjct: 933  IRGFRQYSDDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYD 992

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            TPEQIL+EFFH+RLEFYEKR                 KVRFILGVV GEI+V+NRKR DL
Sbjct: 993  TPEQILEEFFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTDL 1052

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
             LEL++KGFTPFPK  KSIEA +AG  T++ EE+E+N EV+ G V++ DY+YLLSMAIG+
Sbjct: 1053 LLELRQKGFTPFPKNSKSIEAVVAG-ATDETEESEENPEVVNG-VQSIDYDYLLSMAIGT 1110

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LTLEKVQ L AD+D+L  EVD+L+++TP+SLW+KDLDALD QLDE DK+DA+AE  R  +
Sbjct: 1111 LTLEKVQGLLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLDELDKSDARAEEERMKI 1170

Query: 1133 KGKVMTEAGLK--ASRAVKNPRKNNTKKANNPPIEATVSSAV-EIGNPSEVLKPKGRGGP 963
            KG   ++AG K  A RA KN RKN+ KK+NN    A  + A+ E+ N ++V+KPKGR G 
Sbjct: 1171 KGNGNSDAGPKIVAKRAPKNARKND-KKSNN----ARATEAMGEMDNVTKVVKPKGRAGL 1225

Query: 962  RKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSE---APARTKEPS 792
            +KAPA+K +                    LA+  L+ SPDQS  M++E    PA+ KEPS
Sbjct: 1226 KKAPAEKLDDEEEDEVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEKVQVPAKKKEPS 1285

Query: 791  KRAAAKKPPLSTFTEISDDDGNMDDEMQM---IPEEKKGDNDDSDGD---FEPEVEVVXX 630
            KR AA+K  ++  T  S+D+  +DD+       PE  K     + G+    +P  E    
Sbjct: 1286 KRTAAQKKAVTVETSDSEDEIIIDDDEAFEIAAPEAGKKGGRKAAGNTKAAKPAAET--- 1342

Query: 629  XXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMRA 450
                                        +  L Q+L+T+ LKP E+   SPEKK+RKMRA
Sbjct: 1343 -----------------KKRGPAKKQQPEASLGQRLLTEMLKPTES---SPEKKVRKMRA 1382

Query: 449  SPFNKKSGSVLGRIGT 402
            SPFNKKSGS+LGR GT
Sbjct: 1383 SPFNKKSGSMLGRAGT 1398


>ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2-like [Solanum lycopersicum]
          Length = 1477

 Score = 1162 bits (3005), Expect = 0.0
 Identities = 595/903 (65%), Positives = 704/903 (77%), Gaps = 2/903 (0%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+PSFLVEFITPIVKAT+K+GR+
Sbjct: 518  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFLVEFITPIVKATHKSGRI 577

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            L+FY+MPEYE W+ SLG T++G SIK  KGLGTSTSKEGKEYF+DL  H+KDFVW D QD
Sbjct: 578  LAFYTMPEYEAWRRSLGATSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFVWADNQD 637

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G++I+LAFSKKKIEARKNWLRQFEPGT+LDQKEK I Y++FVNKELILFSMADLQRSIPS
Sbjct: 638  GESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPS 697

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            M+DGLKPGQRKILFC+FKRNFVKEAK++QF+GYVSEHSAYHHGEQSLSSTIIGMAQDYVG
Sbjct: 698  MLDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 757

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNN+NLLQPNGQFGTR+ GGKDHAS+RYIYTRLSPI RFLFPKDDD +LDYLNEDGQSIE
Sbjct: 758  SNNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKDDDTILDYLNEDGQSIE 817

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT YVP+IPTVLVNGSEGIGTGWSSY+PNYNPRD+VAN+R LLN E MEPMDPWYKGFKG
Sbjct: 818  PTWYVPVIPTVLVNGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDELMEPMDPWYKGFKG 877

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
             IEKTATKE GA+YTV+GIIEEV+ETTLRI+ELPVRRWT+DYK+FLES+    DK K+ F
Sbjct: 878  KIEKTATKETGATYTVTGIIEEVSETTLRISELPVRRWTEDYKQFLESMTVSTDKAKDSF 937

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            IK+ R + D+ +V FEVIMSE+NL++A+ EGL+KKFKLTTTISTSNMHLFD KG IKKYD
Sbjct: 938  IKEVRAYGDENSVCFEVIMSEDNLLLAQQEGLLKKFKLTTTISTSNMHLFDSKGKIKKYD 997

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
             PE+IL+EF+H+RLE+YEKR                 KV+FILGVV+GEIIV+NRKRA+L
Sbjct: 998  APEEILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKGEIIVNNRKRAEL 1057

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
             LEL+ KGFTPFPKK K +EA +A  +T+DA+++E++ E     VRASDY+YLLSMAIG+
Sbjct: 1058 LLELKNKGFTPFPKK-KPVEAVVAD-STDDADDSEESPEESSRGVRASDYDYLLSMAIGT 1115

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LTLEKVQELCAD+D+L  EV++++ +TPK LWMKDLD LDKQLDEQDK D Q E AR+ L
Sbjct: 1116 LTLEKVQELCADRDKLNAEVEDMRNATPKHLWMKDLDVLDKQLDEQDKIDIQTEEAREKL 1175

Query: 1133 KGKVMTEAGLKASRAVKNPRKNNTK-KANNPPIEATVSSAVEIGNPSEVLKPKGRGGPRK 957
            K KVM  AG  A +    PRK N K ++    ++ +  S  E  N SEV+KPKGRG P K
Sbjct: 1176 KKKVMNAAGKAAPK--PKPRKTNKKAESTAESMDVSFGSTAETANVSEVVKPKGRGRPAK 1233

Query: 956  APAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEAP-ARTKEPSKRAA 780
            A      K                   LAAYNL+SSPD+S   ++E P A+TK P+KRAA
Sbjct: 1234 A------KPIVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEVPKAQTKAPAKRAA 1287

Query: 779  AKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXXXXXXXXXXXX 600
            A+K  L +  ++SD +  ++ +               D +FEP   V             
Sbjct: 1288 AQKKALPSTPDVSDGEDAIEID---------------DDEFEPAAAVGGKKKGGRKPAAA 1332

Query: 599  XXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMRASPFNKKSGSV 420
                               Q + Q+LIT  LKP E+AG+SP++K+RKMRASPFNKKSG+V
Sbjct: 1333 KAAAAPKPPGKKAPANNQSQSVGQRLITQVLKPAEDAGVSPDRKVRKMRASPFNKKSGAV 1392

Query: 419  LGR 411
            +G+
Sbjct: 1393 MGK 1395


>ref|XP_006439078.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
            gi|557541274|gb|ESR52318.1| hypothetical protein
            CICLE_v10030505mg [Citrus clementina]
          Length = 1455

 Score = 1161 bits (3003), Expect = 0.0
 Identities = 616/916 (67%), Positives = 716/916 (78%), Gaps = 12/916 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNG+V
Sbjct: 517  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGKV 576

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFYSMP+YE WKESLGG  +  SIK  KGLGTSTSKEGKEYF+++ LHKKDFVW D+QD
Sbjct: 577  LSFYSMPDYEAWKESLGGNASSWSIKYYKGLGTSTSKEGKEYFQNITLHKKDFVWEDDQD 636

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G+AI+LAFSKKKIEARK WL QFEPG +LDQKEK IKYSDFVNKELILFSMADLQRSIPS
Sbjct: 637  GEAIELAFSKKKIEARKKWLLQFEPGNHLDQKEKYIKYSDFVNKELILFSMADLQRSIPS 696

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNF+KEAK+AQF+GYVSEHSAYHHGEQSL+STI+GMAQD+VG
Sbjct: 697  MVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTILGMAQDFVG 756

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLLQPNGQFGTR+QGGKD ASARYI+TRLSPITRFLFPKDDD LLDYLNEDGQ IE
Sbjct: 757  SNNINLLQPNGQFGTRNQGGKDAASARYIFTRLSPITRFLFPKDDDKLLDYLNEDGQQIE 816

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT Y+PIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM PWY+GF+G
Sbjct: 817  PTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMHPWYRGFRG 876

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
            TIEKTA+KEAG +YTV+GIIEEVNETTLRI ELP+RRWTQDY+EFLESI+  ND     F
Sbjct: 877  TIEKTASKEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQNDS----F 932

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            I+ +R+++DDTTV FEV +SEE+++  K EGL+KKFKLTTTISTSNMHLFD KGVIKKYD
Sbjct: 933  IRGFRQYSDDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLFDSKGVIKKYD 992

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            TPEQIL+EFFH+RLEFYEKR                 KVRFILGVV GEI+V+NRKR DL
Sbjct: 993  TPEQILEEFFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVVNNRKRTDL 1052

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
             LEL++KGFTPFPK  KSIEA +AG  T++ EE+E+N EV+ G V++ DY+YLLSMAIG+
Sbjct: 1053 LLELRQKGFTPFPKNSKSIEAVVAG-ATDETEESEENPEVVNG-VQSIDYDYLLSMAIGT 1110

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LTLEKVQ L AD+D+L  EVD+L+++TP+SLW+KDLDALD QLD  DK+DA+AE  R  +
Sbjct: 1111 LTLEKVQGLLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLD-LDKSDARAEEERMKI 1169

Query: 1133 KGKVMTEAGLK--ASRAVKNPRKNNTKKANNPPIEATVSSAV-EIGNPSEVLKPKGRGGP 963
            KG   ++AG K  A RA KN RKN+ KK+NN    A  + A+ E+ N ++V+KPKGR G 
Sbjct: 1170 KGNGNSDAGPKIVAKRAPKNARKND-KKSNN----ARATEAMGEMDNVTKVVKPKGRAGL 1224

Query: 962  RKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSE---APARTKEPS 792
            +KAPA+K +                    LA+  L+ SPDQS  M++E    PA+ KEPS
Sbjct: 1225 KKAPAEKLDDEEEDEVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEKVQVPAKKKEPS 1284

Query: 791  KRAAAKKPPLSTFTEISDDDGNMDDEMQM---IPEEKKGDNDDSDGD---FEPEVEVVXX 630
            KR AA+K  ++  T  S+D+  +DD+       PE  K     + G+    +P VE    
Sbjct: 1285 KRTAAQKKAVTVETSDSEDEIIIDDDEAFEIAAPEAGKKGGRKAAGNTKAAKPAVET--- 1341

Query: 629  XXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMRA 450
                                        +  L Q+L+T+ LKP E+   SPEKK+RKMRA
Sbjct: 1342 -----------------KKRGPAKKQQPEASLGQRLLTEMLKPTES---SPEKKVRKMRA 1381

Query: 449  SPFNKKSGSVLGRIGT 402
            SPFNKKSGS+LGR GT
Sbjct: 1382 SPFNKKSGSMLGRAGT 1397


>ref|XP_002298421.2| DNA topoisomerase family protein [Populus trichocarpa]
            gi|550348289|gb|EEE83226.2| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 1485

 Score = 1157 bits (2993), Expect = 0.0
 Identities = 618/934 (66%), Positives = 704/934 (75%), Gaps = 28/934 (2%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQ-------------DHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFI 2973
            KSLRYGHLMIMTDQ             DHDGSHIKGLLINF+HSFWPSLLK+PSFLVEFI
Sbjct: 522  KSLRYGHLMIMTDQAKERFANFLCFKQDHDGSHIKGLLINFLHSFWPSLLKVPSFLVEFI 581

Query: 2972 TPIVKATNKNGRVLSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLD 2793
            TPIVKAT++NG VLSFYSMPEYE WK SL G  +G SIK  KGLGTSTSKEGK YF+ LD
Sbjct: 582  TPIVKATHRNGTVLSFYSMPEYESWKGSLAGNASGWSIKYYKGLGTSTSKEGKAYFQSLD 641

Query: 2792 LHKKDFVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELI 2613
             HKKDF+W+DEQDGDAI+LAFSKKKIEARKNWLRQ+EPGT+LDQ +KLIKYSDF+NKELI
Sbjct: 642  KHKKDFIWMDEQDGDAIELAFSKKKIEARKNWLRQYEPGTHLDQNQKLIKYSDFINKELI 701

Query: 2612 LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSL 2433
            LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKI+QF+GYVSEHSAYHHGEQSL
Sbjct: 702  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKISQFSGYVSEHSAYHHGEQSL 761

Query: 2432 SSTIIGMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDG 2253
            +STIIGMAQD+VGSNNINLL PNGQFGTR  GGKDHASARYIYT+LSPITRFLFPKDDDG
Sbjct: 762  ASTIIGMAQDFVGSNNINLLLPNGQFGTRSVGGKDHASARYIYTQLSPITRFLFPKDDDG 821

Query: 2252 LLDYLNEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEP 2073
            LLDYL+EDGQ+IEP  Y+PIIP VLVNG EGIGTGWS++IPNYNPRDIVANIR LLNGE 
Sbjct: 822  LLDYLDEDGQTIEPNWYMPIIPMVLVNGCEGIGTGWSTFIPNYNPRDIVANIRRLLNGEM 881

Query: 2072 MEPMDPWYKGFKGTIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLE 1893
            MEPM+PWY+GFKGTIEK A+KEAG SYTV+G+I EVNETTLRITELP+RRWT DYK FL 
Sbjct: 882  MEPMNPWYRGFKGTIEKGASKEAGCSYTVNGVINEVNETTLRITELPIRRWTDDYKAFLN 941

Query: 1892 SIMTGN-----DKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTI 1728
            S+  GN     +  K+PFIKD+R++ DD TV FEV++SEEN+++AK EGL+KKFKLTTTI
Sbjct: 942  SVTEGNRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQEGLLKKFKLTTTI 1001

Query: 1727 STSNMHLFDPKGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFI 1548
            STSNMHLFD  GVIKKYD PEQIL+EFFHLRLE+YE+R                 KVRFI
Sbjct: 1002 STSNMHLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEFELLKLENKVRFI 1061

Query: 1547 LGVVRGEIIVSNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIG 1368
            LGVVRGEIIV+NRKRADLFLEL +KGFTP PKK K++ A      T+D +E ED+ EV G
Sbjct: 1062 LGVVRGEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAG----ATDDKDEAEDSLEVSG 1117

Query: 1367 GKVRASDYEYLLSMAIGSLTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQ 1188
              VRASDY+YLLSMAIG+LTLEKVQ+LCAD D+L  EVD L+++TP  LW+KDL+AL+ Q
Sbjct: 1118 --VRASDYDYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDLEALEMQ 1175

Query: 1187 LDEQDKNDAQAEVARKALKGKVMTEAGLKASR-AVKNPRKNNTKKANNPPIEATV----- 1026
            LD  DK DA+AE ARK LKG    EAG K S+ A KNPRK  TKKA N  +         
Sbjct: 1176 LDVLDKYDAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKY-TKKAINEEVSVETMGKAS 1234

Query: 1025 SSAVEIGNPSEVLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSP 846
            SSA+E  N +EV+KPKGR G RKAPAKKQEK +                   AY LDSSP
Sbjct: 1235 SSAMETENAAEVVKPKGRAGSRKAPAKKQEKPSPISDEDDEIESLKDRLK--AYRLDSSP 1292

Query: 845  DQSAAMDSEAPARTKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSD 666
            +QSA M++E     + P+ R AA+K PL+  + ISD +                D  D D
Sbjct: 1293 EQSADMETEV---LRVPAGRKAARKKPLAAVSVISDSE----------------DEPDLD 1333

Query: 665  GDFEPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXP----MNKQLLNQKLITDTLKPV 498
             DF+ +V+ V                                   Q L Q+L+T+ LKP 
Sbjct: 1334 DDFDVQVKAVPETKKKGGRKAAAANDKAAKPPAATKRRGPASKQSQGLGQQLLTEMLKPA 1393

Query: 497  ENAGISPEKKMRKMRASPFNKKSGSVLGRIGTKD 396
            E +GISPEKK+RKMRASPFNKKSGS+LG I   D
Sbjct: 1394 EESGISPEKKVRKMRASPFNKKSGSLLGGIHKGD 1427


>gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984168|gb|AAN85208.1|
            DNA topoisomerase II [Nicotiana tabacum]
          Length = 1482

 Score = 1154 bits (2984), Expect = 0.0
 Identities = 602/912 (66%), Positives = 715/912 (78%), Gaps = 11/912 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+PSFL+EFITPIVKAT+K+G++
Sbjct: 517  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPSFLIEFITPIVKATHKSGKI 576

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFY+MPEYE W++SLG  ++G SIK  KGLGTSTSKEGKEYF+DL  H+KDF+W D QD
Sbjct: 577  LSFYTMPEYESWRKSLGANSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKDFIWADNQD 636

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G++I+LAFSKKKIEARKNWLRQFEPGT+LDQKEK I Y++FVNKELILFSMADLQRSIPS
Sbjct: 637  GESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMADLQRSIPS 696

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            M+DGLKPGQRKILFC+FKRNFVKEAK++QF+GYVSEHSAYHHGEQSLSSTIIGMAQDYVG
Sbjct: 697  MLDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 756

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNN+NLLQPNGQFGTR+ GGKDHAS+RYIYTRLSPI RFLFPK+DD + DYLNEDGQ IE
Sbjct: 757  SNNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKEDDTIHDYLNEDGQYIE 816

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT YVPI+P VL+NGSEGIGTGWSSY+PNYNPRD+VAN+R LLN EPMEPMDPWYKGFKG
Sbjct: 817  PTWYVPIVPMVLINGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDEPMEPMDPWYKGFKG 876

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
            TIEKTATKEAGA+YTV+GIIEEVNETTLRI+ELPVRRWT+DYK+FLES+   NDK K+PF
Sbjct: 877  TIEKTATKEAGATYTVTGIIEEVNETTLRISELPVRRWTEDYKQFLESMTVSNDKAKDPF 936

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            IK+ R + D+ +V FEVIMSEENL++A+ EGL+KKFKL TTISTSNMHLFD  G IKKYD
Sbjct: 937  IKEVRAYGDENSVCFEVIMSEENLILAQQEGLLKKFKLATTISTSNMHLFDSNGKIKKYD 996

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
             PE IL+EF+H+RLE+YEKR                 KV+FILGVV+ EIIV+NRKRADL
Sbjct: 997  NPEDILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKVEIIVNNRKRADL 1056

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
             LEL++KGFTPFPKK K++EA +A  T++DAE++E   E +   VRA DY+YLLSM IG+
Sbjct: 1057 LLELKEKGFTPFPKK-KAVEAVVAD-TSDDAEDSE---EELNRGVRAGDYDYLLSMPIGT 1111

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LTLEKVQELCA++D+L  EV++++ +TPK LW+KDLD L+KQLDEQDK D QAE AR+ +
Sbjct: 1112 LTLEKVQELCAERDQLNGEVEDMRNATPKLLWLKDLDVLEKQLDEQDKIDIQAEEAREKI 1171

Query: 1133 KGKVMTEAGLKASRAVKNPRKNNTKKAN------NPPIEATVSSAVEIGNPSEVLKPKGR 972
            K KVM  AGLKA +    PRK N KKA+       P    +  ++    N +EV+KPK R
Sbjct: 1172 KKKVMNAAGLKAPK--PKPRK-NVKKASVVESTAEPMDRVSCFNSGNRSNVTEVVKPKAR 1228

Query: 971  GGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSA-AMDSEAP-ARTKE 798
            GG +KAPAK +                     LAAYNL+SSPD SA AM++EAP A+ K 
Sbjct: 1229 GGSKKAPAKAKPIAVEDEEEEEDDEVLALKDRLAAYNLNSSPDHSAEAMETEAPKAQKKA 1288

Query: 797  PSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXXXXXX 618
            P+++AAAKK  L +  ++S+     +DE+++       D+D+S    EPEV V       
Sbjct: 1289 PTRKAAAKKKTLPSIADVSEG----EDEIEI------SDDDES----EPEVAVGGKKKGG 1334

Query: 617  XXXXXXXXXXXXXXXXXXXXXPMNKQL--LNQKLITDTLKPVENA-GISPEKKMRKMRAS 447
                                 P NKQ   + QKLIT  LKP EN    SPEKK+RKMRAS
Sbjct: 1335 RKPATAKAAPAAAKQPPKKRGPANKQAVGIGQKLITSILKPAENTDNSSPEKKVRKMRAS 1394

Query: 446  PFNKKSGSVLGR 411
            PFN+KSG+VLG+
Sbjct: 1395 PFNEKSGAVLGK 1406


>ref|XP_002314046.2| DNA topoisomerase family protein [Populus trichocarpa]
            gi|550331162|gb|EEE88001.2| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 1482

 Score = 1139 bits (2945), Expect = 0.0
 Identities = 605/928 (65%), Positives = 705/928 (75%), Gaps = 22/928 (2%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+PSFLVEFITPIVKAT++NG V
Sbjct: 521  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTV 580

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFYSMPEYE WKESL G  +G SIK  KGLGTSTSKEGK+YFK+L  HKKDF+W+DE D
Sbjct: 581  LSFYSMPEYEYWKESLSGNASGWSIKYYKGLGTSTSKEGKDYFKNLHKHKKDFLWMDELD 640

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            GDAI+LAFSKKKIEARKNWLRQ EPGT+LD  +K+IKYSDF+NKELILFSMADLQRSIPS
Sbjct: 641  GDAIELAFSKKKIEARKNWLRQHEPGTHLDHNQKIIKYSDFINKELILFSMADLQRSIPS 700

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNFVKEAK++QF+GYVSEHSAYHHGEQSL+ TIIGMAQD+VG
Sbjct: 701  MVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLAGTIIGMAQDFVG 760

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLLQPNGQFGTR  GGKDHASARYIYT+LSPITRFLFPKDDDGLL+YL+EDGQ+IE
Sbjct: 761  SNNINLLQPNGQFGTRSVGGKDHASARYIYTQLSPITRFLFPKDDDGLLNYLDEDGQTIE 820

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT Y+PIIPTVLVNG EGIGTGWS++IPNYNPRD+VANIR LLNGE MEPM+PWY+GFKG
Sbjct: 821  PTWYMPIIPTVLVNGCEGIGTGWSTFIPNYNPRDVVANIRRLLNGEMMEPMNPWYRGFKG 880

Query: 2033 TIEKTATKEAG-ASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGN-----D 1872
            TIEK A+KE G +SYTV+G+I EVNETTLRITELP+RRWT DYK FL S+  G      +
Sbjct: 881  TIEKGASKEGGCSSYTVNGVINEVNETTLRITELPIRRWTDDYKAFLNSVTEGTRDENGN 940

Query: 1871 KIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKG 1692
              K+PF+KD+R++ DD  VHFEV +SEEN+++AK EGL+KKFKLTTTISTSNMHLFD  G
Sbjct: 941  LPKDPFVKDFRKYGDDAAVHFEVQLSEENMLVAKQEGLLKKFKLTTTISTSNMHLFDSAG 1000

Query: 1691 VIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSN 1512
            VIKKYD PEQIL+ FFHLRLE+YE R                 KVRFILGVVRGEIIV+N
Sbjct: 1001 VIKKYDNPEQILENFFHLRLEYYETRKKVLLENLEFELLKLENKVRFILGVVRGEIIVNN 1060

Query: 1511 RKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLL 1332
            RKRADL LEL +KGF   PKK K++ A      T+D EE ED+ +V G  VRASDY+YLL
Sbjct: 1061 RKRADLLLELHQKGFNAIPKKSKAVVAG----ATDDTEEAEDSPDVSG--VRASDYDYLL 1114

Query: 1331 SMAIGSLTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAE 1152
            SMAIG+LTLE+VQ+LCAD+D+L  EVD L+++TPK LW+KDL+AL+ QLD  D+ DA+AE
Sbjct: 1115 SMAIGTLTLERVQQLCADRDKLNGEVDSLRKTTPKVLWVKDLEALEMQLDMLDEYDAEAE 1174

Query: 1151 VARKALKGK-VMTEAGLKASR-AVKNPRKNNTKKANNPPIEATV-----SSAVEIG---N 1002
             AR+ LKG     EAG K S+ A K PRKN TKKA N  +         S A+E     N
Sbjct: 1175 EARRKLKGGGAKGEAGFKVSKQAPKYPRKN-TKKAINEEVSVETTGTSSSFAIETASSEN 1233

Query: 1001 PSEVLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDS 822
             + V+KPKGR G +KAPAK ++                    L AY LDSSP+QSA M++
Sbjct: 1234 AAAVVKPKGRAGSKKAPAKMEKLSPVLDDFDEDDEIESLKDRLNAYRLDSSPEQSADMET 1293

Query: 821  EAPARTKEPSKRAAAKKPPLSTFTEISD--DDGNMDD----EMQMIPEEKKGDNDDSDGD 660
            +     + P++R AA+K PL+  + ISD  D+ N+DD    E++ +PE KK     +   
Sbjct: 1294 DV---LQVPARRGAARKKPLANVSVISDSEDEPNLDDDADVEVKALPETKKKGGRKAAAA 1350

Query: 659  FEPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGIS 480
             +   +                                 Q L QKL+T+ LKP E AGIS
Sbjct: 1351 NDKAAK------------------PPAATKRRGPASQQSQGLGQKLLTEMLKPAEGAGIS 1392

Query: 479  PEKKMRKMRASPFNKKSGSVLGRIGTKD 396
            PEKK+RK+RASPFNKKSGSVLGRI  +D
Sbjct: 1393 PEKKVRKVRASPFNKKSGSVLGRIHKED 1420


>ref|XP_007220582.1| hypothetical protein PRUPE_ppa000202mg [Prunus persica]
            gi|462417044|gb|EMJ21781.1| hypothetical protein
            PRUPE_ppa000202mg [Prunus persica]
          Length = 1471

 Score = 1137 bits (2942), Expect = 0.0
 Identities = 604/917 (65%), Positives = 691/917 (75%), Gaps = 15/917 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKAT+KNG+ 
Sbjct: 524  KSLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATHKNGKS 583

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            L+FYSMPEYE WKESL G  +G SIK  KGLGTSTSKEG++YF++L +HKKDF+W+DE+D
Sbjct: 584  LAFYSMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGRDYFQNLAMHKKDFIWIDERD 643

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G+AI+LAFSKKKIE RKNWLRQFEP  +LDQKEKLIKYSDFV+KELI FSMADLQRSIPS
Sbjct: 644  GEAIELAFSKKKIEERKNWLRQFEPSVHLDQKEKLIKYSDFVHKELIQFSMADLQRSIPS 703

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STIIGMAQDYVG
Sbjct: 704  MVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVG 763

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLLQPNGQFGTR+ GGKDHASARYIYTRLSPITRFLFPKDDD LLDYLNEDGQSIE
Sbjct: 764  SNNINLLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYLNEDGQSIE 823

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT YVPIIPTVLVNGSEGIGTGWSSYIPNYN RDIVAN+R LLNGE M PMDPWY+GF G
Sbjct: 824  PTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNTRDIVANVRRLLNGEAMVPMDPWYRGFSG 883

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
            TIEKT  KE+G SYTV G+IEE NETT+RI+ELP+RRWTQDYKEFLESI  GNDK K+PF
Sbjct: 884  TIEKT-VKESGVSYTVCGVIEEGNETTVRISELPIRRWTQDYKEFLESISQGNDKAKDPF 942

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            I+ + +H+D +TV   V + EENL+ A+ EGL+KKFKLTT+ISTSNMHLFDPKGVIKKYD
Sbjct: 943  IEGFTQHSDHSTVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDPKGVIKKYD 1002

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            TPEQIL+EFFHLRLEFYEKR                 KVRFIL VV GEIIVSNR+RADL
Sbjct: 1003 TPEQILEEFFHLRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIVSNRRRADL 1062

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGK-VRASDYEYLLSMAIG 1317
            FLELQ+KGFTPFPKK K+ E  +AG   ED EE E+NSE   G   R SDYEYL+SMAIG
Sbjct: 1063 FLELQQKGFTPFPKKTKAQEPEVAG-AIEDTEETEENSESASGNGARISDYEYLISMAIG 1121

Query: 1316 SLTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKA 1137
            +LT+E+VQ LCAD+D++ NEV EL+ STP+SLW+KDLDAL+ +L E +K++A AE A+K 
Sbjct: 1122 TLTIERVQALCADRDKVNNEVAELRNSTPRSLWLKDLDALEMELGELEKSEALAEEAKKK 1181

Query: 1136 LKGKVMTEAGLKASR-AVKNPRKNNTKKANNPPI-----EATVSSAVEIGNPSEVLKPKG 975
             + +V      K SR A KNPRKNN KKANN        E + S   E+    E++K K 
Sbjct: 1182 SRNQVKNAPAAKVSRPAPKNPRKNN-KKANNAEAAAESRETSSSFVFEMEKAPEIVKRKV 1240

Query: 974  RGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEA---PART 804
                +KAPA K++ ++                 LAAYNLDSSP+ SA  ++E    P + 
Sbjct: 1241 GAVAKKAPAGKKQAKSAVVLSDDDDEVLELKDRLAAYNLDSSPENSAGKETEVPQEPVQR 1300

Query: 803  KEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXXXX 624
            KEPSKRA              DDD + + E+   P   K     + G  +          
Sbjct: 1301 KEPSKRAMQ-----------IDDDEDFEVEIAAAPAAGKKGGRKAAGTTKAS-------- 1341

Query: 623  XXXXXXXXXXXXXXXXXXXXXXXPMNKQ-----LLNQKLITDTLKPVENAGISPEKKMRK 459
                                     NKQ        QKL+TD LKPVE +G+SPE K+RK
Sbjct: 1342 ------------KPPAAAKKRGAAANKQSQASSSSGQKLLTDMLKPVETSGVSPEPKVRK 1389

Query: 458  MRASPFNKKSGSVLGRI 408
            MRASPFNKKS SV+G++
Sbjct: 1390 MRASPFNKKSSSVMGKV 1406


>ref|XP_004308680.1| PREDICTED: DNA topoisomerase 2-like [Fragaria vesca subsp. vesca]
          Length = 1469

 Score = 1132 bits (2927), Expect = 0.0
 Identities = 598/917 (65%), Positives = 696/917 (75%), Gaps = 10/917 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+PSFLVEFITPIVKAT+KNG+ 
Sbjct: 521  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHKNGKE 580

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            L+FYSMPEYE W+ESL G  +G +IK  KGLGTSTSKEG++YF++LD+HKKDFVW+DE+D
Sbjct: 581  LAFYSMPEYEAWRESLRGNASGWTIKYYKGLGTSTSKEGRDYFQNLDMHKKDFVWIDERD 640

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G+AI+LAFSKKKIE RKNWLRQFEPGT+LDQKEKL+KYSDFV+KELI FSMADLQRSIPS
Sbjct: 641  GEAIELAFSKKKIEERKNWLRQFEPGTHLDQKEKLVKYSDFVHKELIQFSMADLQRSIPS 700

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNF+KEAK+AQF+GYVSEHSAYHHGEQSL+STIIGMAQDYVG
Sbjct: 701  MVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYVG 760

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNIN LQPNGQFGTR+ GGKDHASARYIYTRLSPITRFLFPKDDD LLDYLNEDGQSIE
Sbjct: 761  SNNINFLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYLNEDGQSIE 820

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT YVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNG+ M PMDPWY+GF G
Sbjct: 821  PTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGDEMVPMDPWYRGFTG 880

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
             IEKT  KE G SYT  GIIEEVNETTLRI+ELP+RRWTQDYKEFLESI  GNDK K+PF
Sbjct: 881  FIEKT-VKETGTSYTACGIIEEVNETTLRISELPIRRWTQDYKEFLESISQGNDKAKDPF 939

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            I+ + +H+D +TV   V + EENL+ A+ EGL+KKF+LTT+I+T+NMHLFDPKGVIKKYD
Sbjct: 940  IEGFTQHSDHSTVEILVHLPEENLMAARKEGLLKKFRLTTSIATTNMHLFDPKGVIKKYD 999

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            T EQIL+EFF LRLEFYEKR                 KVRFILGVV GEIIVSNRKRADL
Sbjct: 1000 TAEQILEEFFPLRLEFYEKRKKVLLDNLELELLKMENKVRFILGVVNGEIIVSNRKRADL 1059

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSE-VIGGKVRASDYEYLLSMAIG 1317
            FLELQ+KGFTPFPKK KS+E  +AG  TED EE E+NSE VI   VR SDYEYL+SMAIG
Sbjct: 1060 FLELQQKGFTPFPKKTKSVEPEVAG-ATEDTEETEENSETVISNGVRISDYEYLISMAIG 1118

Query: 1316 SLTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKA 1137
            +LT+E+V+ L AD+D++  +V++L+ STPKSLW+KDLD L+ +L+E +K++A A+ A++ 
Sbjct: 1119 TLTIERVEALLADRDKVNEQVNDLRGSTPKSLWLKDLDVLEAELNELEKSEALADEAKRK 1178

Query: 1136 LKGKVMTEAGL-KASRAVKNPRKNNTKKANNPPI-----EATVSSAVEIGNPSEVLKPKG 975
             +   +  A + K S+    PRK NTKK NN        E + SSA+EI  P EV+K +G
Sbjct: 1179 SRNNQIKNAPVGKVSKQAPKPRK-NTKKVNNAEAIPESRETSSSSAMEIEKPPEVMKRRG 1237

Query: 974  -RGGPRKAPAKKQEKRT-XXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEAPARTK 801
               G +KAPAKKQ K T                  LAAYNLDSSPD+   +  + PA+ K
Sbjct: 1238 VAAGSKKAPAKKQVKSTVVLSDDDDDEEMLDLKDRLAAYNLDSSPDKETEVPLK-PAQKK 1296

Query: 800  EPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXXXXX 621
            E SK+A  K        +  DDD + + E+   P   K       G  +           
Sbjct: 1297 EASKKATLK-------DDEDDDDDDFEVEIAAAPAAVKKGGRKPAGAAKAAAAA------ 1343

Query: 620  XXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKP-VENAGISPEKKMRKMRASP 444
                                          QKL+TD LKP  E++G+SP+ K+RKMR SP
Sbjct: 1344 ------KPPVAAKKRGAAAKKDTQTSSSSGQKLLTDMLKPAAESSGVSPDPKVRKMRESP 1397

Query: 443  FNKKSGSVLGRIGTKDK 393
            FNKKSGSVL R+  +D+
Sbjct: 1398 FNKKSGSVLSRVNLEDE 1414


>ref|XP_006838283.1| hypothetical protein AMTR_s00103p00101630 [Amborella trichopoda]
            gi|548840751|gb|ERN00852.1| hypothetical protein
            AMTR_s00103p00101630 [Amborella trichopoda]
          Length = 1505

 Score = 1110 bits (2870), Expect = 0.0
 Identities = 588/941 (62%), Positives = 691/941 (73%), Gaps = 34/941 (3%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+PSFLVEFITPIVKA NKNG+V
Sbjct: 530  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKARNKNGKV 589

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFY++PEYE WKESLGG   G +IK  KGLGTSTS+EGKEYFK+++ HKKDF+WVD+QD
Sbjct: 590  LSFYTLPEYESWKESLGGNARGWTIKYYKGLGTSTSQEGKEYFKEINKHKKDFIWVDDQD 649

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            GDAI+LAFSKKKIEARKNWLR FEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS
Sbjct: 650  GDAIELAFSKKKIEARKNWLRHFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 709

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNFV +AK+ QF+GYVSEHSAYHHGEQSL++TI+GMAQD+VG
Sbjct: 710  MVDGLKPGQRKILFCSFKRNFVSQAKVVQFSGYVSEHSAYHHGEQSLAATIVGMAQDFVG 769

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            +NNINLLQP GQFGTR++GGKD ASARYI+T LSPITRFLFPKDDD LLDY NEDGQ IE
Sbjct: 770  TNNINLLQPLGQFGTRNRGGKDAASARYIFTCLSPITRFLFPKDDDVLLDYQNEDGQCIE 829

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            P  Y+PIIP VL+NGSEGIGTGWSSY+PNYNPRD+ AN++ LLNGE M PM+PWYKGFKG
Sbjct: 830  PNWYMPIIPLVLINGSEGIGTGWSSYVPNYNPRDVAANVKRLLNGESMLPMEPWYKGFKG 889

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
            TIEK+ATKE G  YTVSGI+EE+NETTLRITELP+RRWT+DYK +LES+ TG++K KEPF
Sbjct: 890  TIEKSATKEGGVGYTVSGIVEEINETTLRITELPIRRWTEDYKVYLESLRTGSEKTKEPF 949

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            I DY+EHN DT VHF+V++ EEN+ +++ EGLMK FKLTTTISTSNMHLF+ KGVIKKYD
Sbjct: 950  IVDYKEHNTDTRVHFDVLLPEENMKISQQEGLMKMFKLTTTISTSNMHLFNAKGVIKKYD 1009

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            TPEQIL+EFFHLRL++Y KR                 K RFILGVV GEI+VS RKRADL
Sbjct: 1010 TPEQILEEFFHLRLDYYGKRKKVLLDNLELELLKLDNKARFILGVVNGEIVVSKRKRADL 1069

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
             LEL+ KGFTPFPKK K++EAA+AG T  D EE E++ EV    + ASDY+YLLSMAIG+
Sbjct: 1070 VLELRDKGFTPFPKKSKNVEAALAGATPVD-EEGEESPEVDDRGINASDYDYLLSMAIGT 1128

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LT+EKVQELCA+KD+L ++V EL+  TPK+LW+KDLDA   QLD +   +A+ +      
Sbjct: 1129 LTIEKVQELCAEKDKLEHDVKELRGLTPKALWIKDLDAFLAQLDAEAVQEAKDDEYEL-- 1186

Query: 1133 KGKVMTEAGLKASRAVKNPRKNNTKKANNPPIEATVSSAVEIGNPSEVLKPKGRGGPRKA 954
               ++++A     +  KNPRKN  K A   P E   + A +        KPK R  P+KA
Sbjct: 1187 -NNMVSDAAKIFRQVGKNPRKNTKKPA---PAEHVDTDASDTTTTEVAAKPKKRA-PKKA 1241

Query: 953  PAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEAPARTKEPSKRAAAK 774
            P KK+                     LA YN++SSP+  A M+++ P R +EPSKRA +K
Sbjct: 1242 PTKKK----VDVEDMEDDLLLDLNARLAKYNIESSPEH-ADMETDLPER-REPSKRAVSK 1295

Query: 773  KPPLSTFTEISDDDGNMDDEMQMI----------------------PEEKK--------- 687
              P   + +ISDD+    +E++                        P+EKK         
Sbjct: 1296 --PQQVYADISDDESEHLEEIEEEKEEEQEDEDPKPAKGKKKQAPKPKEKKKMDGSSDEE 1353

Query: 686  ---GDNDDSDGDFEPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLIT 516
                D D S  D E E                                  + +LNQKLIT
Sbjct: 1354 FVISDEDLSVFDIETEDAPPKPKGRAKKPLSNKPKAPTGAAKKRGAASSKQPILNQKLIT 1413

Query: 515  DTLKPVENAGISPEKKMRKMRASPFNKKSGSVLGRIGTKDK 393
            + LKPV   G+SPEKK+RKMRASPFNKKSGSVLGRI  + K
Sbjct: 1414 EVLKPV---GVSPEKKVRKMRASPFNKKSGSVLGRIERESK 1451


>ref|XP_007009329.1| Topoisomerase II isoform 3 [Theobroma cacao]
            gi|508726242|gb|EOY18139.1| Topoisomerase II isoform 3
            [Theobroma cacao]
          Length = 1244

 Score = 1101 bits (2847), Expect = 0.0
 Identities = 556/725 (76%), Positives = 626/725 (86%), Gaps = 5/725 (0%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+PSF+VEFITPIVKAT+K   V
Sbjct: 518  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMVEFITPIVKATHKTKGV 577

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFYSMPEYE WKESLGG   G SIK  KGLGTSTSKEGK+YFK+LD H+K+FVW DEQD
Sbjct: 578  LSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKEFVWQDEQD 637

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G+AI+LAFSKKKIEARKNWLRQFEPGT+LDQ +KLIKYS+F+NKELILFSMADLQRSIPS
Sbjct: 638  GEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMADLQRSIPS 697

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            M+DGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STI+GMAQD+VG
Sbjct: 698  MIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIVGMAQDFVG 757

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLL P GQFGTR+QGGKD ASARYI+T LSPITR+LFPKDDDGLLDYLNEDGQSIE
Sbjct: 758  SNNINLLNPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYLNEDGQSIE 817

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            P  YVPIIP VLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM PWY+GFKG
Sbjct: 818  PIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPWYRGFKG 877

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
             IEKTA+KEAG +YT++GIIEEV+ETTLRITELPVRRWTQDY+EFLESI+TGND    PF
Sbjct: 878  NIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND----PF 933

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            IK++R+++DDTTV FEVI++EEN+++AK EGL+KKFKLTTTISTSNMHLFD KG+IKKYD
Sbjct: 934  IKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKGMIKKYD 993

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            TPEQIL+EFFHLR EFYEKR                 KVRFILGVV+GEIIV+NRKRADL
Sbjct: 994  TPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNNRKRADL 1053

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGS 1314
            FLELQ KGFTPFPKK K++E A+AG  T+D EE E+NSEV    ++ASDY+YLLSMAIGS
Sbjct: 1054 FLELQTKGFTPFPKKAKTVEVAVAG-ATDDTEETEENSEVSAKGLQASDYDYLLSMAIGS 1112

Query: 1313 LTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKAL 1134
            LTLEKVQELCAD+D+L  EV++L+++TPKSLW+KDLD L+ QLDEQDK  AQAE A K +
Sbjct: 1113 LTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDK-AAQAEEAAKLV 1171

Query: 1133 KGKVMTEAGLKASR-AVKNPRKNNTKKANNPPIEATV----SSAVEIGNPSEVLKPKGRG 969
            KG+   EAG +A R A K PRK N K+ N   +  T     SSA+E       +KPKGRG
Sbjct: 1172 KGR--GEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETETAPAAVKPKGRG 1229

Query: 968  GPRKA 954
            G RKA
Sbjct: 1230 GSRKA 1234


>gb|EYU27037.1| hypothetical protein MIMGU_mgv1a000169mg [Mimulus guttatus]
          Length = 1503

 Score = 1086 bits (2809), Expect = 0.0
 Identities = 579/910 (63%), Positives = 681/910 (74%), Gaps = 9/910 (0%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGR- 2937
            KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+PSF++EFITPIVKATNK G+ 
Sbjct: 534  KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFMLEFITPIVKATNKYGKN 593

Query: 2936 VLSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQ 2757
              SFY+MP+YE WKES+G      +IK  KGLGTST KEGKEYF+DL  HKKDFVWVDEQ
Sbjct: 594  KKSFYTMPQYEAWKESIGSDAKNWTIKYYKGLGTSTDKEGKEYFEDLGKHKKDFVWVDEQ 653

Query: 2756 DGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIP 2577
            DGDAI+LAFSKKKIEARK+WLRQFEPGTYLD ++  IKY DFV+KELILFS+ADLQRSIP
Sbjct: 654  DGDAIELAFSKKKIEARKSWLRQFEPGTYLDDRDSHIKYRDFVHKELILFSIADLQRSIP 713

Query: 2576 SMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYV 2397
            SMVDGLKPGQRKIL+CSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STIIGMAQDYV
Sbjct: 714  SMVDGLKPGQRKILYCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMAQDYV 773

Query: 2396 GSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSI 2217
            GSNNINLL PNGQFGTR QGGKDHASARY+YT+LSP+TRFLFPK DD LLDYLNEDGQ I
Sbjct: 774  GSNNINLLLPNGQFGTRGQGGKDHASARYVYTQLSPVTRFLFPKADDILLDYLNEDGQMI 833

Query: 2216 EPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFK 2037
            EPT YVPIIPTVLVNGSEGIGTGWSS++PNYNP DI+AN+R LLNGEPME M PWYKGFK
Sbjct: 834  EPTWYVPIIPTVLVNGSEGIGTGWSSFVPNYNPLDIIANVRHLLNGEPMEAMHPWYKGFK 893

Query: 2036 GTIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEP 1857
            GTIEKTATKEAG SYTV+GIIEEV+ETTL ITELP+RRWTQDYKEFLESI   NDK K+P
Sbjct: 894  GTIEKTATKEAGFSYTVTGIIEEVDETTLTITELPIRRWTQDYKEFLESISAENDKSKDP 953

Query: 1856 FIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKY 1677
            FI+  R+++    +HF V +SE NL++AK EGL+KKFKLTTT+STSNMHLFD KGVIKKY
Sbjct: 954  FIEGCRDNSGGEIIHFAVYLSETNLLVAKQEGLLKKFKLTTTMSTSNMHLFDSKGVIKKY 1013

Query: 1676 DTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRAD 1497
            D+PEQIL+EFF++RLEFYEKR                 K RFI GVV G I+VSNRK+AD
Sbjct: 1014 DSPEQILEEFFYIRLEFYEKRKKALLANLELDMLKCDNKYRFIRGVVEGTIVVSNRKKAD 1073

Query: 1496 LFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEV-IGGKVRASDYEYLLSMAI 1320
            LFLEL+ KGFTPFPKK  + E A+AG  T+D EE EDN+EV I   V ASDY+YLLS+AI
Sbjct: 1074 LFLELKAKGFTPFPKKKNTPEVAVAG-ATDDTEETEDNTEVEIAKGVSASDYDYLLSLAI 1132

Query: 1319 GSLTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKN-DAQAEVAR 1143
            G+LT EK+QEL  +++RLT EV++LK+ST KSLW KDLDAL+ ++ E  KN + + E  R
Sbjct: 1133 GTLTAEKLQELRDERERLTQEVEDLKKSTVKSLWTKDLDALEAKIIEDLKNSEKKWEEDR 1192

Query: 1142 KALKGKVMTEAGLKASRAVKNPRKNNTKKANNPP-IEATVSSAVEIGNPSEVLKPKGR-- 972
            + ++G     A   A    KN +K  TKK +    ++ + ++  E    +E+ KP+G+  
Sbjct: 1193 QRIQGGETKIARPLAKNPRKNTKKATTKKESTAEHMDVSDNTVTETDKVAEIKKPRGKAA 1252

Query: 971  GGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEAP---ARTK 801
               +KAP  K                      +AAYN DSSPD++  M++E P    + K
Sbjct: 1253 AAKKKAPVAKV---VAEADEDDDDGVAELRQRIAAYNFDSSPDRAEDMETELPQLQTKKK 1309

Query: 800  EPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXXXXX 621
            EP+KRAA +K  +S    +SDD+   DD++++I           D DFEPE +       
Sbjct: 1310 EPTKRAAPRKKQVSI---VSDDE--EDDDIEII----------DDDDFEPE-DKKKKGGR 1353

Query: 620  XXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISPEKKMRKMRASPF 441
                                      QL+ QKLIT+ LKP   A  SPEKK+R+MRASPF
Sbjct: 1354 KPANPKAAAAKPPAGAKKRGPASKQSQLVGQKLITEVLKPTAAADDSPEKKVRRMRASPF 1413

Query: 440  NKKSGSVLGR 411
            NKKS S+LGR
Sbjct: 1414 NKKSSSILGR 1423


>ref|XP_002517802.1| DNA topoisomerase II, putative [Ricinus communis]
            gi|223543074|gb|EEF44609.1| DNA topoisomerase II,
            putative [Ricinus communis]
          Length = 1212

 Score = 1069 bits (2764), Expect = 0.0
 Identities = 570/923 (61%), Positives = 676/923 (73%), Gaps = 21/923 (2%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            K LRYGHLMIMTDQD+DGSHIKGLLINFI+ FWPSLLKIPSFLVEFITPIVKAT+++G++
Sbjct: 236  KPLRYGHLMIMTDQDYDGSHIKGLLINFIYYFWPSLLKIPSFLVEFITPIVKATHRSGKI 295

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            LSFY+MPEY  WKESL G  NG +IK  KGLGT+  KEG +YF+D+D H+KDFVW++E+D
Sbjct: 296  LSFYTMPEYYSWKESLMGNANGWTIKYYKGLGTNDKKEGMQYFRDIDKHQKDFVWMNEED 355

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G AI+LAFSKKK++ RKNWLR F+PGT+L+QK KLIKYSDF+NKELILFS+ADLQRSIPS
Sbjct: 356  GTAIELAFSKKKVDERKNWLRHFQPGTHLEQKNKLIKYSDFINKELILFSVADLQRSIPS 415

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKP QRKILF  FKRN VK+ K+ Q  GYVSE SAYHHGEQSL STI+GMAQ++VG
Sbjct: 416  MVDGLKPAQRKILFSCFKRNLVKDLKVVQLQGYVSEQSAYHHGEQSLQSTIVGMAQNFVG 475

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLL P GQFGTR  GGKDHAS RYIYT LSPITRFLFPKDDD LLDYL EDG SIE
Sbjct: 476  SNNINLLAPKGQFGTRCSGGKDHASPRYIYTCLSPITRFLFPKDDDCLLDYLQEDGLSIE 535

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT Y PIIP VLVNG EGIGTGWS++IPNYNPRDIVAN+R  LNGE MEPM PWYKGFKG
Sbjct: 536  PTWYAPIIPLVLVNGCEGIGTGWSTFIPNYNPRDIVANLRRFLNGEKMEPMHPWYKGFKG 595

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTG-----NDK 1869
            TIEK+A+KE G SY V+GIIEEVNETT+RITELP+RRWT +YK+FL S++        + 
Sbjct: 596  TIEKSASKEGGGSYAVNGIIEEVNETTVRITELPIRRWTDEYKDFLNSVIENVRDEKGNL 655

Query: 1868 IKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGV 1689
             K+ FIKD+R++ DD +V FEV++SEE +   K EGL+KKFKL TTISTSNMHLFDPKGV
Sbjct: 656  PKDAFIKDFRKYGDDVSVCFEVLLSEEKMKQVKDEGLLKKFKLATTISTSNMHLFDPKGV 715

Query: 1688 IKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNR 1509
            IKKYD+PE+IL+EF HLR E YEKR                 KVRFILGVV GEIIV+NR
Sbjct: 716  IKKYDSPEEILEEFVHLRFELYEKRKNFKLASLEMEALILENKVRFILGVVTGEIIVNNR 775

Query: 1508 KRADLFLELQKKGFTPFPKKIKSIEAAIAGVT--TEDAEENEDNSEVIGGKVRASDYEYL 1335
            KRA+L LEL++KGFTPFPK  K +EA +AG    TE++E  ED  E     V+A+DYEYL
Sbjct: 776  KRAELLLELRQKGFTPFPKN-KPVEAVVAGAADDTEESESTEDVEENSKTGVQATDYEYL 834

Query: 1334 LSMAIGSLTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQA 1155
            LSM+IG+LTLEKVQ+LCADKD+++ EV+ L+R+ PK LW+KDL+A + QLD+ D  DA  
Sbjct: 835  LSMSIGTLTLEKVQKLCADKDKISEEVENLRRTAPKDLWLKDLEAFESQLDKLDAEDA-- 892

Query: 1154 EVARKALKGKVMTEAGLKASR-AVKNPRKNNTKKANNPPIEA-----TVSSAVEIGNPSE 993
             + R+        + G K SR   KNPRKNN K A N    A     T +SA+E  + SE
Sbjct: 893  -LERQKSVKDTNGQGGFKVSRQPPKNPRKNN-KTAKNTEAAAEIMGQTSNSAMETESVSE 950

Query: 992  VLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEAP 813
             +KPKGR   +KAPAKKQEK T                 L AY LDSSP+QS  M+++ P
Sbjct: 951  EVKPKGRAASKKAPAKKQEKPT-PISDDEDDEVEALKDRLKAYRLDSSPEQSTTMETDMP 1009

Query: 812  --ARTKEPSKRAAAKKPPLSTFTEI--SDDDGNMDDEMQM----IPEEKKGDNDDSDGDF 657
                 KE SKRAAA+K P++T +E+  S+D+ ++DDE  +    +PE KK       G  
Sbjct: 1010 QVPARKETSKRAAAQKKPVATISELSESEDEVDLDDESDVEVVPVPEAKK------KGGR 1063

Query: 656  EPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKPVENAGISP 477
            +P                                    Q L QKL+T+ LKP EN GISP
Sbjct: 1064 KPAAN-------------SRAAKPPAGTKKRGPTKKESQGLGQKLLTEMLKPAENPGISP 1110

Query: 476  EKKMRKMRASPFNKKSGSVLGRI 408
            EKK+RKMRASPFNKKSGSVLGR+
Sbjct: 1111 EKKVRKMRASPFNKKSGSVLGRV 1133


>ref|XP_004149716.1| PREDICTED: DNA topoisomerase 2-like [Cucumis sativus]
          Length = 1459

 Score = 1066 bits (2758), Expect = 0.0
 Identities = 580/921 (62%), Positives = 681/921 (73%), Gaps = 27/921 (2%)
 Frame = -3

Query: 3074 QDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRVLSFYSMPEYE*WK 2895
            QDHDGSHIKGLLINFIHSFWPSLL++PSFLVEFITPIVKAT+KNG VLSFY+MPEYE WK
Sbjct: 498  QDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWK 557

Query: 2894 ESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQDGDAIDLAFSKKKI 2715
            ESL G  +G SIK  KGLGTSTSKEG+EYF+ L  HKKDF+W D+ DG+AI+LAFSKKKI
Sbjct: 558  ESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKI 617

Query: 2714 EARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL 2535
            E RKNWLRQFEPGT+LDQ  KLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL
Sbjct: 618  EDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKIL 677

Query: 2534 FCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVGSNNINLLQPNGQF 2355
            FCSFKRNF+KEAK++QF+GYVSEHSAYHHGEQSL+STIIGMAQD+VGSNNINLL PNGQF
Sbjct: 678  FCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQF 737

Query: 2354 GTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIEPTCYVPIIPTVLV 2175
            GTR+ GGKDHAS+RYIYT+LS +TRFLFP+DDD LL+YLNEDGQSIEPT Y+PIIPTVLV
Sbjct: 738  GTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLV 797

Query: 2174 NGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKGTIEKTATKEAGAS 1995
            NGSEGIGTGWSSY+PNYNPRDI+ N+R +L GE M PMDPWY+GF GTIEKTATKE G +
Sbjct: 798  NGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTT 857

Query: 1994 YTVSGIIEEVNETTLRITELPVRRWTQDYKEFLES---IMTGNDKIKE-----PFIKDYR 1839
            YTVSGIIEEV++TTLRI ELPVRRWT DYK+FL+S   + + +DK KE     PFI+   
Sbjct: 858  YTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQAD 917

Query: 1838 EHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYDTPEQI 1659
             H+DD  V  +V ++EEN+++A  EGL KKFKLTTT+STSNMHLFD  GVIKKYDTPEQI
Sbjct: 918  HHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQI 977

Query: 1658 LQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADLFLELQ 1479
            L+EFF LRLEFYEKR                 KVRFIL VV  EI VSNRK+ DLF ELQ
Sbjct: 978  LEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQ 1037

Query: 1478 KKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEYLLSMAIGSLTLEK 1299
             KGFTPFPKK KS+E  IAG + E  +E E++ EV+ G+ R SDYEYLL++ IG+LT+EK
Sbjct: 1038 AKGFTPFPKKTKSVEPEIAGASNE-TDEAEESPEVVKGE-RISDYEYLLALPIGTLTIEK 1095

Query: 1298 VQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARKALKGKVM 1119
            VQELC+D+D+L  EVD+L+++TPKSLW+ DLD L+K+LDE D+NDAQ    RK  + K  
Sbjct: 1096 VQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKAN 1155

Query: 1118 TEAGLKASR-AVKNPRKNNTKKANN-----PPIEATVSS-AVEIGNPSEVLKPKGRGGPR 960
             +   K SR A K PR  N+KK +N       ++ T SS   E+ N + V+KPKG+  PR
Sbjct: 1156 IDLKPKVSRNAPKAPR--NSKKTSNVETVTESMDTTYSSTTTEVAN-NPVVKPKGKAAPR 1212

Query: 959  KAPAKKQEKRT--XXXXXXXXXXXXXXXXXLAAYNLDSSPDQS--AAMDSEA------PA 810
            KAPAKK+ K                     LAAY ++SSP+ S  +AM++E        A
Sbjct: 1213 KAPAKKKGKAAVLDDDEDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQQQAA 1272

Query: 809  RTKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXX 630
            + KEPSKRA AKK   +   +IS  D                  DD+DGDFE + EV   
Sbjct: 1273 KKKEPSKRAPAKKKTTAKSAQISISD------------------DDNDGDFEIK-EVDPP 1313

Query: 629  XXXXXXXXXXXXXXXXXXXXXXXXXPMNKQLLNQKLITDTLKP-VENAGISPEKKMRKMR 453
                                     P     L QKLIT  L+P  EN+GISPEKK+RK+R
Sbjct: 1314 AAKKGGGRGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGISPEKKVRKIR 1373

Query: 452  ASPFNKKSGSVLGR-IGTKDK 393
            ASPFNKKSGS+LGR IG +++
Sbjct: 1374 ASPFNKKSGSLLGRTIGEEEE 1394


>gb|EXB68160.1| DNA topoisomerase 2 [Morus notabilis]
          Length = 1451

 Score = 1066 bits (2757), Expect = 0.0
 Identities = 577/913 (63%), Positives = 670/913 (73%), Gaps = 12/913 (1%)
 Frame = -3

Query: 3113 KSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFLVEFITPIVKATNKNGRV 2934
            KSLRYGHLMIMTDQ                                         KNG+ 
Sbjct: 523  KSLRYGHLMIMTDQ-------------------------------------ATQKKNGKE 545

Query: 2933 LSFYSMPEYE*WKESLGGTTNG*SIK*NKGLGTSTSKEGKEYFKDLDLHKKDFVWVDEQD 2754
            L+FY+MPEYE WK+SL G  +G SIK  KGLGTSTSKEG+EYF++LD HKKDF+W+DEQD
Sbjct: 546  LAFYTMPEYEAWKDSLRGNASGWSIKYYKGLGTSTSKEGREYFQNLDKHKKDFLWIDEQD 605

Query: 2753 GDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPS 2574
            G+AI+LAFSKKKIE RKNWLR+FEPGT+LDQKEKLIKYSDFV+KELILFS+ADLQRSIPS
Sbjct: 606  GEAIELAFSKKKIEERKNWLRRFEPGTHLDQKEKLIKYSDFVHKELILFSLADLQRSIPS 665

Query: 2573 MVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMAQDYVG 2394
            MVDGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+ TIIGMAQD+VG
Sbjct: 666  MVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDFVG 725

Query: 2393 SNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNEDGQSIE 2214
            SNNINLL PNGQFGTR+ GGKDHASARYI+T+LSPITR LFPKDDD LLD+LNEDG SIE
Sbjct: 726  SNNINLLMPNGQFGTRNLGGKDHASARYIFTQLSPITRSLFPKDDDLLLDFLNEDGLSIE 785

Query: 2213 PTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWYKGFKG 2034
            PT YVPIIPTVL NGSEGIGTGWSSYIPNYNPRDIVAN+R LL+G+ M PM PWY+GFKG
Sbjct: 786  PTWYVPIIPTVLANGSEGIGTGWSSYIPNYNPRDIVANVRRLLDGDEMVPMIPWYRGFKG 845

Query: 2033 TIEKTATKEAGASYTVSGIIEEVNETTLRITELPVRRWTQDYKEFLESIMTGNDKIKEPF 1854
            TIEK++ +   AS+ VSG++EEVNETT+RITELP+RRWTQDYKEFL+SI  GNDK K+PF
Sbjct: 846  TIEKSSKE---ASFFVSGLMEEVNETTVRITELPIRRWTQDYKEFLDSICYGNDKAKDPF 902

Query: 1853 IKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGVIKKYD 1674
            I+D+ +H+D +TV   V ++EE L+  K EGL+KK KLTT+IST+NMHLFD  GVIKKYD
Sbjct: 903  IEDFTQHSDHSTVDILVHLAEETLIAVKQEGLLKKLKLTTSISTANMHLFDANGVIKKYD 962

Query: 1673 TPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXKVRFILGVVRGEIIVSNRKRADL 1494
            TPEQIL+EF+HLRLEFYEKR                 KVRFILGVV GEI+VSNRKRADL
Sbjct: 963  TPEQILEEFYHLRLEFYEKRKKALLDNLELELLKLANKVRFILGVVTGEIVVSNRKRADL 1022

Query: 1493 FLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNS--EVIGGKVRASDYEYLLSMAI 1320
            F+ELQ+KGFTPFPKK K++E  +AGV TEDAE+ E+NS  E I  + R SDYEYLLSMAI
Sbjct: 1023 FVELQRKGFTPFPKKTKAVEPEVAGV-TEDAEDTEENSNAEAISTEARISDYEYLLSMAI 1081

Query: 1319 GSLTLEKVQELCADKDRLTNEVDELKRSTPKSLWMKDLDALDKQLDEQDKNDAQAEVARK 1140
            G+LTLEKVQ LC +KD+L NEV+EL+++TPKSLW+KDLDAL+ QLDE +K+DAQAE ARK
Sbjct: 1082 GTLTLEKVQALCGEKDKLNNEVEELRKATPKSLWVKDLDALETQLDELNKSDAQAEEARK 1141

Query: 1139 ALKGKVMTEAGLKASR-AVKNPRKNNTKKANNPPIEATVS----SAVEIGNPSEVLKPKG 975
              KG+V   A  K SR A K PRK NTKKA+N    A ++    SA+E     EV KPKG
Sbjct: 1142 KSKGQVKNAAVSKVSRQAPKVPRK-NTKKASNAEAIADITENFDSAMEFEKAPEVAKPKG 1200

Query: 974  RGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXLAAYNLDSSPDQSAAMDSEA---PART 804
            R GP+KA +K                       LAAYNLDSSPD+S+ MD+EA   P   
Sbjct: 1201 RAGPKKAASKV----VVEDDDDDDDEVLALKDRLAAYNLDSSPDKSSEMDTEAPQVPVPK 1256

Query: 803  KEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGDNDDSDGDFEPEVEVVXXXX 624
            K P+KRAAA+K  L+T +E  + D + DDE+        GD D       P         
Sbjct: 1257 KAPTKRAAAQKKTLATVSETVNLDDDDDDEID-------GDEDFELESTAPAKAAAKKGG 1309

Query: 623  XXXXXXXXXXXXXXXXXXXXXXXPMNK--QLLNQKLITDTLKPVENAGISPEKKMRKMRA 450
                                     NK  Q+L QKL+TD LKP EN+G+SPEKK+RKMRA
Sbjct: 1310 KKPAVSTKAVSKAPAAAATKRRGAANKEPQVLGQKLLTDMLKPAENSGLSPEKKVRKMRA 1369

Query: 449  SPFNKKSGSVLGR 411
            SPFNKKSGSVLGR
Sbjct: 1370 SPFNKKSGSVLGR 1382