BLASTX nr result
ID: Akebia25_contig00017002
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Akebia25_contig00017002
(711 letters)
Database: ./nr
38,876,450 sequences; 13,856,398,315 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|AAU20768.1| 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltra... 149 1e-33
sp|Q9LEL5.1|4OMT_COPJA RecName: Full=3'-hydroxy-N-methyl-(S)-coc... 143 6e-32
gb|ABY75613.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclau... 143 6e-32
dbj|BAM37633.1| 3'-hydroxy-N-methylcoclaurine-4'-O-methyltransfe... 135 1e-29
gb|AAP45313.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclau... 134 2e-29
gb|AAP45314.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclau... 134 3e-29
gb|AAU20765.1| (S)-norcoclaurine 6-O-methyltransferase [Thalictr... 130 4e-28
gb|ACO90241.1| norcoclaurine 6-O-methyltransferase [Thalictrum f... 127 4e-27
dbj|BAM37634.1| O-methyltransferase [Eschscholzia californica] 125 1e-26
sp|Q9LEL6.1|6OMT_COPJA RecName: Full=(RS)-norcoclaurine 6-O-meth... 125 1e-26
gb|ACO90250.1| norcoclaurine 6-O-methyltransferase-like protein ... 119 1e-24
gb|ACO90232.1| putative norcoclaurine 6-O-methyltransferase [Pap... 118 2e-24
sp|Q6WUC1.1|6OMT_PAPSO RecName: Full=(RS)-norcoclaurine 6-O-meth... 115 1e-23
gb|AAP45315.1| S-adenosyl-L-methionine:norcoclaurine 6-O-methylt... 115 2e-23
gb|AFB74613.1| O-methyltransferase 3 [Papaver somniferum] gi|388... 110 5e-22
gb|ACO90225.1| putative norcoclaurine 6-O-methyltransferase [Pap... 103 7e-20
ref|XP_002529795.1| o-methyltransferase, putative [Ricinus commu... 102 1e-19
ref|XP_002534989.1| o-methyltransferase, putative [Ricinus commu... 102 1e-19
gb|AFK73710.1| narcotoline-O-methyltransferase [Papaver somniferum] 101 2e-19
gb|AFB74612.1| O-methyltransferase 2 [Papaver somniferum] 101 2e-19
>gb|AAU20768.1| 3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase
[Thalictrum flavum subsp. glaucum]
Length = 348
Score = 149 bits (375), Expect = 1e-33
Identities = 69/99 (69%), Positives = 84/99 (84%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
LKL+L DW+D+D ++ILK+C++AV +D GK+IIVDV LDE+SDHELS RL LDIDMLVN
Sbjct: 250 LKLILHDWNDEDSIKILKQCRKAVPKDGGKVIIVDVALDEDSDHELSSTRLILDIDMLVN 309
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERTKEDW K++KCAG G KIR +A +QS IEVFP
Sbjct: 310 TGGKERTKEDWEKLVKCAGFSGCKIRHIAAIQSVIEVFP 348
>sp|Q9LEL5.1|4OMT_COPJA RecName: Full=3'-hydroxy-N-methyl-(S)-coclaurine
4'-O-methyltransferase; AltName:
Full=S-adenosyl-L-methionine:3'-hydroxy-N-
methylcoclaurine 4'-O-methyltransferase; Short=4'-OMT
gi|9711916|dbj|BAB08005.1|
S-adenosyl-L-methionine:3'-hydroxy-N-methylcocla urine
4'-O-methyltransferase [Coptis japonica]
Length = 350
Score = 143 bits (360), Expect = 6e-32
Identities = 69/99 (69%), Positives = 81/99 (81%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
LKL+L DW+D+D ++ILK+C+ AV +D GK+IIVDV LDEESDHELS RL LDIDMLVN
Sbjct: 252 LKLILHDWNDEDSIKILKQCRNAVPKDGGKVIIVDVALDEESDHELSSTRLILDIDMLVN 311
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERTKE W KI+K AG G KIR +A +QS IEVFP
Sbjct: 312 TGGKERTKEVWEKIVKSAGFSGCKIRHIAAIQSVIEVFP 350
>gb|ABY75613.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine
4'-O-methyltransferase [Coptis chinensis]
Length = 350
Score = 143 bits (360), Expect = 6e-32
Identities = 69/99 (69%), Positives = 81/99 (81%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
LKL+L DW+D+D ++ILK+C+ AV +D GK+IIVDV LDEESDHELS RL LDIDMLVN
Sbjct: 252 LKLILHDWNDEDSIKILKQCRNAVPKDGGKVIIVDVALDEESDHELSSTRLILDIDMLVN 311
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERTKE W KI+K AG G KIR +A +QS IEVFP
Sbjct: 312 TGGKERTKEVWEKIVKSAGFSGCKIRHIAAIQSVIEVFP 350
>dbj|BAM37633.1| 3'-hydroxy-N-methylcoclaurine-4'-O-methyltransferase [Eschscholzia
californica]
Length = 353
Score = 135 bits (341), Expect = 1e-29
Identities = 60/99 (60%), Positives = 83/99 (83%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
LKL+L DWSD+D V+ILK+C+EAV +D G++IIVDV L+EES+H L++ RL LD+DMLVN
Sbjct: 255 LKLILHDWSDEDSVKILKKCREAVPQDTGRVIIVDVALEEESEHPLTKTRLVLDVDMLVN 314
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGG+ER+++DW K++K AG + +KIR +A +QS IE FP
Sbjct: 315 TGGRERSEDDWAKLLKLAGFRTHKIRHIAAVQSVIEAFP 353
>gb|AAP45313.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine
4'-O-methyltransferase 1 [Papaver somniferum]
Length = 354
Score = 134 bits (338), Expect = 2e-29
Identities = 62/99 (62%), Positives = 80/99 (80%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
LK VL DW+D+ CV ILK+CKEA+ ++ GK+IIVDV L+EES+HEL++ARL LDIDMLVN
Sbjct: 256 LKCVLHDWTDEHCVNILKKCKEAIPKETGKVIIVDVALEEESEHELTKARLILDIDMLVN 315
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGG+ERT EDW ++K AG + +KIR + +QS IE FP
Sbjct: 316 TGGRERTAEDWENLLKRAGFRSHKIRPIRAIQSVIEAFP 354
>gb|AAP45314.1| S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine
4'-O-methyltransferase 2 [Papaver somniferum]
gi|571330882|gb|AHF27397.1|
S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine
4'- O-methyltransferase 2 [synthetic construct]
Length = 357
Score = 134 bits (337), Expect = 3e-29
Identities = 60/99 (60%), Positives = 81/99 (81%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
LKL+L DW+D++CV ILK+CKEA+ ++ GK+IIVDV L+EES+HEL++ RL LDIDMLVN
Sbjct: 259 LKLILHDWTDEECVNILKKCKEAIPKETGKVIIVDVALEEESNHELTKTRLILDIDMLVN 318
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGG+ERT +DW ++K AG + +KIR + +QS IE FP
Sbjct: 319 TGGRERTADDWENLLKRAGFRSHKIRPIRAIQSVIEAFP 357
>gb|AAU20765.1| (S)-norcoclaurine 6-O-methyltransferase [Thalictrum flavum subsp.
glaucum]
Length = 350
Score = 130 bits (327), Expect = 4e-28
Identities = 55/99 (55%), Positives = 79/99 (79%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K +L DW DK+C+ ILKRCK+AV D GK+II+D++LD +S+H ++ RLTLD+DM++N
Sbjct: 251 MKCILHDWDDKECIEILKRCKDAVPRDGGKVIIIDIILDVKSEHPYTKMRLTLDLDMMLN 310
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERT+E+W K+I AG +GYKI ++ +QS IE +P
Sbjct: 311 TGGKERTEEEWKKLIHDAGYKGYKITHISAVQSVIEAYP 349
>gb|ACO90241.1| norcoclaurine 6-O-methyltransferase [Thalictrum flavum]
Length = 125
Score = 127 bits (319), Expect = 4e-27
Identities = 53/99 (53%), Positives = 78/99 (78%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K +L DW DK+C+ ILKRCK+AV D GK+II+D++LD +S+H ++ RL+ D+DM++N
Sbjct: 26 MKCILHDWDDKECIEILKRCKDAVPRDGGKVIIIDIILDVKSEHPYTKMRLSYDLDMMLN 85
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERT+E+W K+I AG +GYKI ++ +QS IE +P
Sbjct: 86 TGGKERTEEEWKKLIHDAGYKGYKITEISALQSVIEAYP 124
>dbj|BAM37634.1| O-methyltransferase [Eschscholzia californica]
Length = 351
Score = 125 bits (315), Expect = 1e-26
Identities = 56/99 (56%), Positives = 76/99 (76%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K +L DW+D +C+ ILK+CKEAV ++ GK+IIVD+VLD ES H S+ RLTLD+DM++N
Sbjct: 252 MKCILHDWNDDECIEILKKCKEAVPKEGGKVIIVDIVLDMESKHPYSKVRLTLDLDMMLN 311
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
T GKERT+E+W K+I AG YKI ++ +QS IE FP
Sbjct: 312 TEGKERTEEEWKKLIDGAGFASYKITQISALQSVIEAFP 350
>sp|Q9LEL6.1|6OMT_COPJA RecName: Full=(RS)-norcoclaurine 6-O-methyltransferase; AltName:
Full=S-adenosyl-L-methionine:norcoclaurine
6-O-methyltransferase; Short=6-OMT
gi|9711914|dbj|BAB08004.1|
S-adenosyl-L-methionine:norcoclaurine
6-O-methyltransferase [Coptis japonica]
Length = 347
Score = 125 bits (314), Expect = 1e-26
Identities = 55/99 (55%), Positives = 77/99 (77%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K +L DW DK+C+ ILKRCKEAV GK+IIVD+VL+ +S+H ++ RLTLD+DM++N
Sbjct: 248 MKCILHDWDDKECIEILKRCKEAVPVKGGKVIIVDIVLNVQSEHPYTKMRLTLDLDMMLN 307
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERT+E+W K+I AG +G+KI + +QS IE +P
Sbjct: 308 TGGKERTEEEWKKLIHDAGYKGHKITQITAVQSVIEAYP 346
>gb|ACO90250.1| norcoclaurine 6-O-methyltransferase-like protein [Thalictrum
flavum]
Length = 346
Score = 119 bits (298), Expect = 1e-24
Identities = 55/100 (55%), Positives = 76/100 (76%), Gaps = 1/100 (1%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K VL DW D +C+ ILKRCK+AV D GK+II+DVVL+ +S+H ++ RLTLD+DM++N
Sbjct: 246 MKGVLHDWDDNECIEILKRCKDAVPRDGGKVIIIDVVLNVKSEHPYTKMRLTLDLDMMLN 305
Query: 508 TGGKERTKEDWGKII-KCAGCQGYKIRLVAVMQSFIEVFP 624
GKERT+EDW K+I AG +GYKI ++ +QS IE +P
Sbjct: 306 NKGKERTEEDWKKLIYDDAGYKGYKITQISALQSVIEAYP 345
>gb|ACO90232.1| putative norcoclaurine 6-O-methyltransferase [Papaver bracteatum]
Length = 346
Score = 118 bits (296), Expect = 2e-24
Identities = 52/99 (52%), Positives = 77/99 (77%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K +L DW+D++C++ILKRCKEA+ +D GK+IIVDVV+D +S H ++ RLTLD+DM++N
Sbjct: 248 MKCILHDWNDEECIQILKRCKEALPKD-GKVIIVDVVIDMDSTHPYAKIRLTLDLDMMLN 306
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERTKE+W + AG +K+ ++ +QS IE +P
Sbjct: 307 TGGKERTKEEWKILFDAAGFASHKVTQISAVQSVIEAYP 345
>sp|Q6WUC1.1|6OMT_PAPSO RecName: Full=(RS)-norcoclaurine 6-O-methyltransferase; Short=6OMT
gi|33286374|gb|AAQ01669.1| (R,S)-norcoclaurine
6-O-methyltransferase [Papaver somniferum]
gi|571330878|gb|AHF27395.1| (R,S)-norcoclaurine
6-O-methyltransferase [synthetic construct]
Length = 346
Score = 115 bits (289), Expect = 1e-23
Identities = 51/99 (51%), Positives = 75/99 (75%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K +L DW+D +C++ILKRCKEA+ + GK+IIVDVV+D +S H ++ RLTLD+DM++N
Sbjct: 248 MKCILHDWNDDECIQILKRCKEALPKG-GKVIIVDVVIDMDSTHPYAKIRLTLDLDMMLN 306
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERTKE+W + AG +K+ ++ +QS IE +P
Sbjct: 307 TGGKERTKEEWKTLFDAAGFASHKVTQISAVQSVIEAYP 345
>gb|AAP45315.1| S-adenosyl-L-methionine:norcoclaurine 6-O-methyltransferase
[Papaver somniferum]
Length = 346
Score = 115 bits (287), Expect = 2e-23
Identities = 51/99 (51%), Positives = 75/99 (75%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K +L DW+D +C++ILKRCKEA+ + GK+IIVDVV+D +S H ++ RLTLD+DM++N
Sbjct: 248 MKCILHDWNDDECIQILKRCKEALPKV-GKVIIVDVVIDMDSTHPYAKIRLTLDLDMMLN 306
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERTKE+W + AG +K+ ++ +QS IE +P
Sbjct: 307 TGGKERTKEEWKTLFDAAGFASHKVTQISAVQSVIEAYP 345
>gb|AFB74613.1| O-methyltransferase 3 [Papaver somniferum]
gi|388571230|gb|AFK73711.1| O-methyltransferase [Papaver
somniferum]
Length = 339
Score = 110 bits (275), Expect = 5e-22
Identities = 49/99 (49%), Positives = 75/99 (75%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K +L +W+D++C++ILKRCKEA+ + GK+II DVV+D +S H S++RL +D+ M+++
Sbjct: 241 MKSILHEWNDEECIQILKRCKEAIPKG-GKVIIADVVIDMDSTHPYSKSRLAMDLAMMLH 299
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
TGGKERT+EDW K+I AG KI ++ +QS IE +P
Sbjct: 300 TGGKERTEEDWKKLIDAAGFASCKITKLSALQSVIEAYP 338
>gb|ACO90225.1| putative norcoclaurine 6-O-methyltransferase [Papaver bracteatum]
Length = 357
Score = 103 bits (256), Expect = 7e-20
Identities = 53/100 (53%), Positives = 70/100 (70%), Gaps = 3/100 (3%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
+K +L DW+D +CV+ILKRCKE V GK+I+V++V+D E H S+ RLTLD+DMLVN
Sbjct: 259 MKNILHDWNDDECVQILKRCKEVVSVG-GKVILVEMVMDTELAHPYSKLRLTLDLDMLVN 317
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVA---VMQSFIEV 618
GGKE T+E+W K+I AG YKI ++ QS IEV
Sbjct: 318 NGGKEGTEEEWKKLIYAAGFTSYKITQMSAGFAAQSVIEV 357
>ref|XP_002529795.1| o-methyltransferase, putative [Ricinus communis]
gi|223530706|gb|EEF32577.1| o-methyltransferase,
putative [Ricinus communis]
Length = 345
Score = 102 bits (254), Expect = 1e-19
Identities = 49/102 (48%), Positives = 71/102 (69%), Gaps = 1/102 (0%)
Frame = +1
Query: 322 ANLKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDML 501
A L VL DW+D DC++ILK+CKEAV E +GK+IIV+ V+ E D +L RL LD+ M+
Sbjct: 244 AFLMWVLHDWNDDDCIQILKKCKEAVTEGNGKVIIVEAVIGEAKDDKLEYVRLMLDMVMM 303
Query: 502 VNTG-GKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
+T GKERT ++WG +++ AG + + I+ + +QS IE FP
Sbjct: 304 AHTNTGKERTSKEWGYVLQKAGFRSHTIKPIGAVQSVIEAFP 345
>ref|XP_002534989.1| o-methyltransferase, putative [Ricinus communis]
gi|255595314|ref|XP_002536276.1| o-methyltransferase,
putative [Ricinus communis] gi|223520217|gb|EEF26107.1|
o-methyltransferase, putative [Ricinus communis]
gi|223524235|gb|EEF27393.1| o-methyltransferase,
putative [Ricinus communis]
Length = 110
Score = 102 bits (254), Expect = 1e-19
Identities = 48/106 (45%), Positives = 73/106 (68%), Gaps = 1/106 (0%)
Frame = +1
Query: 310 FI*IANLKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLD 489
F + L+ +L DW+D +C++ILK+CKEAV ED+GK+IIV+ V+ E D +L RL LD
Sbjct: 5 FCYLYQLQWILHDWNDDECIQILKKCKEAVPEDNGKVIIVEAVIGEVKDDKLEYVRLMLD 64
Query: 490 IDMLVNTG-GKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
+ M+ +T GKERT ++W +I+ AG + + I+ + +QS IE FP
Sbjct: 65 MVMMAHTNTGKERTSKEWESVIQKAGFRSHTIKPIGAVQSIIEAFP 110
>gb|AFK73710.1| narcotoline-O-methyltransferase [Papaver somniferum]
Length = 356
Score = 101 bits (252), Expect = 2e-19
Identities = 45/99 (45%), Positives = 72/99 (72%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
LK VL +W D +CV +LKRCKEAV D GK+II+D+V+D++ + L++A+L+LD+ ++ +
Sbjct: 258 LKYVLHNWEDTECVNLLKRCKEAVPADKGKVIIMDLVIDDDDNSILTQAKLSLDLTVMNH 317
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
GG+ERTKEDW +I+ +G ++I ++ M S I +P
Sbjct: 318 GGGRERTKEDWRNLIEMSGFSRHEIIPISAMPSIIVAYP 356
>gb|AFB74612.1| O-methyltransferase 2 [Papaver somniferum]
Length = 356
Score = 101 bits (252), Expect = 2e-19
Identities = 45/99 (45%), Positives = 72/99 (72%)
Frame = +1
Query: 328 LKLVLRDWSDKDCVRILKRCKEAVQEDDGKIIIVDVVLDEESDHELSRARLTLDIDMLVN 507
LK VL +W D +CV +LKRCKEAV D GK+II+D+V+D++ + L++A+L+LD+ ++ +
Sbjct: 258 LKYVLHNWEDTECVNLLKRCKEAVPADKGKVIIMDLVIDDDDNSILTQAKLSLDLTVMNH 317
Query: 508 TGGKERTKEDWGKIIKCAGCQGYKIRLVAVMQSFIEVFP 624
GG+ERTKEDW +I+ +G ++I ++ M S I +P
Sbjct: 318 GGGRERTKEDWRNLIEMSGFSRHEIIPISAMPSIIVAYP 356