BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Akebia24_contig00005983
         (3215 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]              1120   0.0  
ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis v...  1110   0.0  
ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobro...  1105   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                1082   0.0  
ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform ...  1070   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]      1066   0.0  
ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citr...  1066   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]               1061   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...  1054   0.0  
ref|XP_002300344.1| DNA topoisomerase family protein [Populus tr...  1054   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]            1054   0.0  
ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis...  1051   0.0  
ref|XP_002317355.1| DNA topoisomerase family protein [Populus tr...  1049   0.0  
emb|CBI28783.3| unnamed protein product [Vitis vinifera]             1044   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]            1044   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                 1035   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]              1034   0.0  
gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Mimulus...  1033   0.0  
ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinife...  1033   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                 1030   0.0  

>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1120 bits (2898), Expect = 0.0
 Identities = 598/910 (65%), Positives = 668/910 (73%), Gaps = 13/910 (1%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQNDGLSGRHPRDAVS 2833
            MAV  CVK K        DEP+VFKR+   SK NQLNS+ KK S + DG SGR   D  S
Sbjct: 1    MAVQACVKEKMMDEIDEDDEPLVFKRSNATSKHNQLNSDTKKSSQRYDGQSGRQVSDVPS 60

Query: 2832 PNGQNTSSHKRKV---------VSSTKALTT---KFTIGNLKESTSIADKSKHSSGKSAG 2689
             NGQ++S+ K K          ++S KA T+      + N K S+S  D+SKHSS K   
Sbjct: 61   TNGQSSSASKGKTTKLSSMKSPIASPKASTSFAKASPVANPKVSSSSDDRSKHSS-KQNT 119

Query: 2688 VNDAGXXXXXXXXXXXNVDSEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLXXXXXXXX 2509
            +N                   DS+D+KPLS RL    T L K +S   +KGL        
Sbjct: 120  INVVKEEKELVNPAAEPYG--DSEDEKPLSARL---FTGLTKGSSNNANKGLINSSPASL 174

Query: 2508 XSEKAKVNXXXXXXXXXXXXXXXSRFKLKSCGPSSVKKYDSDEEKPLASKILQNGSNKRD 2329
               K ++N                R K  + G S+VK Y+SD+ K L S   QNGS  R 
Sbjct: 175  PVPKPEINRYSDDSDDEIPLSSKFRLKANA-GTSTVKSYESDDNKTLVSNFQQNGSINRG 233

Query: 2328 SELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTDD-DDDYVP 2152
            S   KS   +NKRPL +V +SVQS+VKKPKLSDA           KAE K DD DDD+VP
Sbjct: 234  S---KSSIKVNKRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKADDSDDDHVP 290

Query: 2151 IGQRMKKLTVPDNKSQSAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSTKVPP 1972
            I QRMKK     NKS +A                                     +KVPP
Sbjct: 291  ISQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSKS------SKVPP 344

Query: 1971 GSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQPVQLTPEQEEVATMFAVMKDTDYATK 1792
             SGEG+KW TLVH+GVIFPPPYKPHGVKMLY G+PV LTPEQEEVATMFAVM DTDY TK
Sbjct: 345  SSGEGKKWNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMTK 404

Query: 1791 PKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSTDEKKAVKEEKLK 1612
             KF ENFM DWR ILGKNHVI+  E CDFTPIYEWHQREKEKKK+M+ +EKK +KEE+LK
Sbjct: 405  SKFKENFMDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEERLK 464

Query: 1611 QEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPRDITINIGKDAPIP 1432
            QEEKYMWAIV+GVKEKVGNFRVEPP LFRGRGEHPKMGKLK+ IRP DITINIGKDAPIP
Sbjct: 465  QEEKYMWAIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIP 524

Query: 1431 ECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLK 1252
            ECPIPGE WKE++HDNTVTWLAFWNDPI P+EFKYVFLAASSSLKGQSDKEKYEKARLLK
Sbjct: 525  ECPIPGESWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLK 584

Query: 1251 DYIHNIRANYTKDFVSKDISKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 1072
            D+I  IRA YTKDF SKDI+KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV
Sbjct: 585  DFIQGIRAAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 644

Query: 1071 SLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAIGLFKSGKKDGEDLFDKLDTNKLNAHL 892
               PP+ L+FDFLGKDSIRY N VEVELPVYKAI  F++GK+ G+DLFDKLDT+KLNAHL
Sbjct: 645  EPKPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNAHL 704

Query: 891  KELMPGLTAKVFRTYNASITLDGMLSNETKAGDVAEKIVIYQHANKEVAIICNHQRSVSK 712
            K LMPGLTAKVFRTYNASITLD MLS ETK G+VAEKIV+YQHANKEVAIICNHQR+VSK
Sbjct: 705  KGLMPGLTAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSK 764

Query: 711  SHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGKPPLKDADGKQKKNLAPEALERKIAQT 532
            SH AQM+RL+ K+DELK ++D L+TDL RAKKGKPPL+DADGK K+NL PEALERKI QT
Sbjct: 765  SHPAQMTRLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKIGQT 824

Query: 531  NAKIEKMERDMRTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAW 352
            NAKIEKMERD  TKE LKT+ALGTSKI+YLDPRI+VAWCKRHEVPIEK+FNKSLLAKFAW
Sbjct: 825  NAKIEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSLLAKFAW 884

Query: 351  AMDVDPSFRF 322
            +MDVDPSFRF
Sbjct: 885  SMDVDPSFRF 894


>ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis vinifera]
          Length = 883

 Score = 1110 bits (2872), Expect = 0.0
 Identities = 592/889 (66%), Positives = 654/889 (73%), Gaps = 18/889 (2%)
 Frame = -3

Query: 2934 NKTISKQNQLNSEIKKPSSQNDGLSGRHPRDAVSPNGQNTSSHKRKVVSSTKA-LTTKFT 2758
            N  ++     +SE  KP S    LS R P+     N          V+ S K  +  K +
Sbjct: 8    NPPVANGESEDSEDDKPLSAK--LSARLPKG----NSHVLKGLSSPVLQSQKTKVDVKKS 61

Query: 2757 IGNLKESTSIADKS------KHSSGKSAGVNDAGXXXXXXXXXXXNV----DSEDSDDDK 2608
             G+ ++   ++ K       + SSGKS G                 V     S+DS+D+ 
Sbjct: 62   DGDSEDEVPLSSKFPLKTYVRSSSGKSLGSKGLNSPSLSSHPPETKVGVKESSDDSEDEI 121

Query: 2607 PLSYRLPIASTTLPKSNSPRVSKGLXXXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFK 2428
            PL  +L + S     S+    SKGL         S+KAKVN               S+F+
Sbjct: 122  PLLLKLQLKSRKGASSSKLLDSKGLSSPASSRPQSQKAKVNNKNLSDDSEDEIPLSSKFR 181

Query: 2427 LKSCGPSSVKKYDS-DEEKPLASKILQNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAV 2251
            LK+   +S+ K D+ DE+KPL S +  NG +K+D E VKS K  NKRPL   +TS  S+ 
Sbjct: 182  LKTGMGASLDKLDNFDEKKPLTSTLKPNGISKKDDERVKSPKGQNKRPLGQANTSHHSSS 241

Query: 2250 KKPKLSDAXXXXXXXXXXXKAESKTDDDDD------YVPIGQRMKKLTVPDNKSQSAXXX 2089
            KKPKL D            KAE K DDDDD      Y P  +R+KK    DNK  S    
Sbjct: 242  KKPKLLDGSVKGKVKQVSVKAEQKDDDDDDNDDDDEYTPTVKRLKKSVSSDNKKASKTKV 301

Query: 2088 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPP 1909
                                              TKVPP SGEGQKWTTL H+GVIFPPP
Sbjct: 302  IPSSRKKATKKAKKSKKLAKSSKYSKS-------TKVPPNSGEGQKWTTLEHNGVIFPPP 354

Query: 1908 YKPHGVKMLYNGQPVQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVI 1729
            YKPHGVKMLYNG+PV LTPEQEEVATMFAVMKDTDYATKP+FIENFM DWR  LGKNHVI
Sbjct: 355  YKPHGVKMLYNGRPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRVRLGKNHVI 414

Query: 1728 KKFELCDFTPIYEWHQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFR 1549
            KKFELCDFTPIYEWH++EKEKKKQM+T+EKKA+KEEKLKQE+KYMWA+VDGVKEKVGNFR
Sbjct: 415  KKFELCDFTPIYEWHEKEKEKKKQMTTEEKKALKEEKLKQEDKYMWAVVDGVKEKVGNFR 474

Query: 1548 VEPPGLFRGRGEHPKMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWL 1369
            VEPPGLFRGRGEHPKMGKLK+RI P DITINIGK+AP+PECPIPGERWKEV+HDNTVTWL
Sbjct: 475  VEPPGLFRGRGEHPKMGKLKKRICPSDITINIGKEAPVPECPIPGERWKEVRHDNTVTWL 534

Query: 1368 AFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVSKDISK 1189
            AFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYI NIRA YTKDF +KD  K
Sbjct: 535  AFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIQNIRATYTKDFTNKDTMK 594

Query: 1188 RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYF 1009
            RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+LVPPN+L+FDFLGKDSIRYF
Sbjct: 595  RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNKLEFDFLGKDSIRYF 654

Query: 1008 NTVEVELPVYKAIGLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITL 829
            NTVEVELPVYKAIG FK+GK  G+DLFDKLDT+KLNAHLKELMPGLTAKVFRTYNASITL
Sbjct: 655  NTVEVELPVYKAIGQFKTGKSGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITL 714

Query: 828  DGMLSNETKAGDVAEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMD 649
            D ML+ E + GD  EKIVIYQHANKEVAIICNHQRSVSKSH  QMSRLSEKM EL+ V+D
Sbjct: 715  DEMLNREARGGDAMEKIVIYQHANKEVAIICNHQRSVSKSHDVQMSRLSEKMRELQGVLD 774

Query: 648  ELKTDLTRAKKGKPPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVA 469
            ELKTDL RAKKGKPPLKD+DGK KKN+ PE LERKIAQTN KIEKMERDM+TKEDLKTVA
Sbjct: 775  ELKTDLARAKKGKPPLKDSDGKPKKNMTPEVLERKIAQTNTKIEKMERDMKTKEDLKTVA 834

Query: 468  LGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            LGTSKINYLDPRISVAWCKR EVPIEKIFNKSLLAKFAWAMDVDPSFRF
Sbjct: 835  LGTSKINYLDPRISVAWCKRQEVPIEKIFNKSLLAKFAWAMDVDPSFRF 883


>ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
            gi|590606147|ref|XP_007020665.1| DNA topoisomerase I
            alpha isoform 1 [Theobroma cacao]
            gi|508720292|gb|EOY12189.1| DNA topoisomerase I alpha
            isoform 1 [Theobroma cacao] gi|508720293|gb|EOY12190.1|
            DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
          Length = 904

 Score = 1105 bits (2858), Expect = 0.0
 Identities = 593/920 (64%), Positives = 671/920 (72%), Gaps = 23/920 (2%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTIS-KQNQLNSEIKKPSSQ-NDGLSGRHPRDA 2839
            MAV+   K  +       D P+VFKRN T S KQNQLNSE+KK SSQ +DG SGR   D 
Sbjct: 1    MAVEAPAKHVYDFDDDDDDGPVVFKRNNTSSSKQNQLNSEVKKASSQRSDGQSGRQVSDV 60

Query: 2838 VSPNGQNTSSHKRKVVSS-------------------TKALTTKFTIGNLKESTSIADKS 2716
             SPNGQ++++ K K +SS                   TKAL  K  + N K STS+ D+S
Sbjct: 61   RSPNGQSSNAPKNKSISSSKSPPVKSPILSPKASTSSTKALPVKSPVVNFKASTSLNDQS 120

Query: 2715 KHSSGKSAGVNDAGXXXXXXXXXXXNVDSEDSDDDKPLSYRLPIASTTLPKSNSPRVSKG 2536
            K +  ++                  N D +D DD  PLS RL        K  S + +KG
Sbjct: 121  KQALKQNMTTAVKEGRSPIKGTTEPNSDDDDDDDSLPLSARL--------KGISNQGNKG 172

Query: 2535 LXXXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKS-CGPSSVKKYDSDEEKPLASK 2359
                          K                 +RF +KS  G SS + +D DE+KPLASK
Sbjct: 173  ASTSAPAQSRRLVPKTEVKVSAEDPDDEAPLSARFNVKSNTGTSSSRLHDCDEKKPLASK 232

Query: 2358 ILQNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESK 2179
            I QNGS  +  +   S  +  KRPL   ++S  S+ KKPK SDA           KAE K
Sbjct: 233  IQQNGSIMKGKQQ-NSSTLSGKRPLDKGNSSDHSSAKKPKTSDAPTTMKTKQVTVKAE-K 290

Query: 2178 TDDDDDYVPIGQRMKKLTVPDNKSQSAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1999
             D+DDD++PI QRMKK T  ++K  S                                  
Sbjct: 291  ADEDDDHMPIAQRMKKSTASNSKLSSMKQKTTKVVSSSFKKINKKSKKEMKSSKYIKS-- 348

Query: 1998 XXXSTKVPPGSGEGQK-WTTLVHSGVIFPPPYKPHGVKMLYNGQPVQLTPEQEEVATMFA 1822
                TKVPP SG+GQK W+TLVH+GVIFP PY PHGVKMLY+G+PV LTPEQEEVATMFA
Sbjct: 349  ----TKVPPSSGDGQKKWSTLVHNGVIFPSPYTPHGVKMLYDGRPVDLTPEQEEVATMFA 404

Query: 1821 VMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSTDE 1642
            VMKDTDY +K +F +NF  DW  +LGKNH IK  + CDFTPIYEWH +EKEKKKQMS++E
Sbjct: 405  VMKDTDYMSKTQFKKNFWEDWSKLLGKNHTIKDLDRCDFTPIYEWHLQEKEKKKQMSSEE 464

Query: 1641 KKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPRDIT 1462
            KKA+KEEKLKQEEK+MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRP DIT
Sbjct: 465  KKALKEEKLKQEEKFMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDIT 524

Query: 1461 INIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDK 1282
            INIGKDAPIPECPIPGERWK++KHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDK
Sbjct: 525  INIGKDAPIPECPIPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDK 584

Query: 1281 EKYEKARLLKDYIHNIRANYTKDFVSKDISKRQIAVATYLIDKLALRAGNEKDDDEADTV 1102
            EKYEKAR+LKDYI NIRA YTKDF +KD+ KRQIAVATYLIDKLALRAGNEKDDDEADTV
Sbjct: 585  EKYEKARMLKDYIKNIRAAYTKDFTTKDVMKRQIAVATYLIDKLALRAGNEKDDDEADTV 644

Query: 1101 GCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAIGLFKSGKKDGEDLFDK 922
            GCCTLKV NV  +PPN+L+FDFLGKDSI+Y NTVEVELPVYKAIG F++GK   +DLFDK
Sbjct: 645  GCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKSKSDDLFDK 704

Query: 921  LDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDVAEKIVIYQHANKEVAI 742
            LDT+KLNAHLKELMPGLTAKVFRTYNASITLD ML+ ETK GDVAEK+V+YQ ANKEVAI
Sbjct: 705  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNKETKDGDVAEKVVVYQRANKEVAI 764

Query: 741  ICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGKPPLKDADGKQKKNLAP 562
            ICNHQRS+SKSH+AQMSRL+EK+ ELK V+ ELK DL RAKKGKPPLKDADGKQK+NL P
Sbjct: 765  ICNHQRSISKSHSAQMSRLTEKITELKGVLKELKIDLDRAKKGKPPLKDADGKQKRNLTP 824

Query: 561  EALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIF 382
            +A+++KI QTNAKIEKMERDM+TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIF
Sbjct: 825  QAIQKKIDQTNAKIEKMERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF 884

Query: 381  NKSLLAKFAWAMDVDPSFRF 322
            NKSLLAKFAWAMDVDP FRF
Sbjct: 885  NKSLLAKFAWAMDVDPDFRF 904


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score = 1082 bits (2798), Expect = 0.0
 Identities = 591/936 (63%), Positives = 662/936 (70%), Gaps = 39/936 (4%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQN-DGLSGRHPRDAV 2836
            MAV+ C  P         DEPIVFKRN + SKQ+Q NSE +K SSQ  DG S R   D+ 
Sbjct: 1    MAVEACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDSR 60

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNL--------------KESTSIADKSKHSS-- 2704
              NG+++S  K ++V  +K    K  + +               K STS A KS  SS  
Sbjct: 61   PANGESSSGQKGRMVPPSKPSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPVSSLP 120

Query: 2703 ------------------GKSAGVNDAGXXXXXXXXXXXNVDSEDSDDDKPLSYRLPIAS 2578
                               KSA V                 DSEDSDD KPLS R   +S
Sbjct: 121  ANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRHSASS 180

Query: 2577 TTLPKSNSPRVSKGLXXXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKS-CGPSSV 2401
            +   K N+ +VSK            EK   +                RF LKS  G S+ 
Sbjct: 181  S---KGNTNQVSKEGSKPENEDSDDEKPLSS----------------RFPLKSGVGESTS 221

Query: 2400 KKYDSDEEKPLASKILQNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXX 2221
            K YDSD++KPLA K+  NGS  RD +  K   + NKRP  D+ +S Q +VKKPKLS    
Sbjct: 222  KAYDSDDDKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTA 281

Query: 2220 XXXXXXXXXKAESKT-DDDDDYVPIGQRMKKLTVPDNKSQSAXXXXXXXXXXXXXXXXXX 2044
                     K E K  DDDDD++PI QR+KK    ++KS S                   
Sbjct: 282  PTNKKQASVKPEPKAEDDDDDHLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKS 341

Query: 2043 XXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQPV 1864
                               +KVPP SGEG+KW  L H+GVIFPPPYKPHG+KMLY G+PV
Sbjct: 342  KKVMKNSKYSKS-------SKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPV 394

Query: 1863 QLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEWH 1684
             LTPEQEEVATMFAVM DTDY  KP+F ENF  DW+ ILGKNHVI+  E CDF+PIYEWH
Sbjct: 395  DLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWH 454

Query: 1683 QREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPK 1504
            Q EKEKKKQM+T+EKKA+KEEKLKQEEKYMWA VDG KEKVGNFRVEPPGLFRGRGEHPK
Sbjct: 455  QSEKEKKKQMTTEEKKALKEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPK 514

Query: 1503 MGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYV 1324
            MGKLK+RIRP DITINIGKDAPIPECP+PGERWKEV+HDNTVTWLAFWNDPINPKEFKYV
Sbjct: 515  MGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYV 574

Query: 1323 FLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVSKDISKRQIAVATYLIDKLAL 1144
            FLAASS+LKG SDKEKYEKARLLKDYI  IRA YTKDF SKD +K+QIAVATYLIDKLAL
Sbjct: 575  FLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLAL 634

Query: 1143 RAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAIGL 964
            RAGNEKDDDEADTVGCCTLKVENV  VPPN L+FDFLGKDSIRY N VEVE  V+KAI  
Sbjct: 635  RAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQ 694

Query: 963  FKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDVAE 784
            F+SGK+   DLFD LDT+KLNAHLKELMPGLTAKVFRTYNASITLD MLS ETK GDVAE
Sbjct: 695  FRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAE 754

Query: 783  KIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGKPP 604
            K+V+YQHANKEVAIICNHQR+VSKSH+AQM RL+EK++ELKAV++ELK+DL+R KKGKPP
Sbjct: 755  KVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPP 814

Query: 603  L--KDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRI 430
            L  K+ADGK K+NL PE+LE+KIAQTNAKIEKMERD  TKEDLKTVALGTSKINYLDPRI
Sbjct: 815  LKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRI 874

Query: 429  SVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            +VAWCKRHEVPIEKIFNKSLLAKF WAMDVDPSFRF
Sbjct: 875  TVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 910


>ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform X1 [Citrus sinensis]
            gi|568842074|ref|XP_006474978.1| PREDICTED: DNA
            topoisomerase 1-like isoform X2 [Citrus sinensis]
            gi|568842076|ref|XP_006474979.1| PREDICTED: DNA
            topoisomerase 1-like isoform X3 [Citrus sinensis]
            gi|568842078|ref|XP_006474980.1| PREDICTED: DNA
            topoisomerase 1-like isoform X4 [Citrus sinensis]
          Length = 902

 Score = 1070 bits (2768), Expect = 0.0
 Identities = 583/923 (63%), Positives = 657/923 (71%), Gaps = 26/923 (2%)
 Frame = -3

Query: 3012 MAVDTCVKP-KFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQN-DGLSGRHPRDA 2839
            MAV+   KP + +      D P VFKRN   S+QN  N E+K+PSS   +G +   P+D 
Sbjct: 1    MAVEASSKPSRVYDFDDDEDGPAVFKRNTAASRQNLANPEVKRPSSSTANGQNSNAPKDK 60

Query: 2838 VSPNGQN--------------TSSHK--------RKVVSSTKALTTKFTIGNLKESTSIA 2725
             + +                 TSS K        R  V S      K  + N KES+ + 
Sbjct: 61   TTVSSSKVLPVKSPPPSQKATTSSAKASPSKSPMRSPVKSPVRSPVKSPVANSKESSPLD 120

Query: 2724 DKSKHSSGKSAGVNDAGXXXXXXXXXXXNVDSEDSDDDKPLSYRLPIASTTLPKSNSPRV 2545
            D+ K S   +A                   D  DS+DDKPLS RL        K NS  V
Sbjct: 121  DRLKQSPQHNALA--VVKKEEIKDGNGLKSDDNDSEDDKPLSARL--------KGNSKNV 170

Query: 2544 SKGLXXXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSCGPSSVKKYDSDEEKPLA 2365
            ++G+         SE   VN               SRF   + G S  K  DSDE+KPLA
Sbjct: 171  NQGIGASKADAAISE---VNVKTDPEDSDDEVPLSSRFPKSNAGTSGAKPIDSDEKKPLA 227

Query: 2364 SKILQNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAE 2185
            SK+ QNGS  R+++  KS  V  KRPL   S+S  S+ KKPK+SD            K E
Sbjct: 228  SKVQQNGSTSRETQQ-KSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVE 286

Query: 2184 SKTDDDDDYVPIGQRMKKLTVPDNKSQSAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2005
             K DDDD ++PI QRMK      N + S                                
Sbjct: 287  KKADDDD-HIPISQRMK------NSAPSVKKSVTNTAKATKSVSSSSNKINKKTKKVIKN 339

Query: 2004 XXXXXSTKVPPGSGEGQK-WTTLVHSGVIFPPPYKPHGVKMLYNGQPVQLTPEQEEVATM 1828
                 STK+ PGSG+GQK WTTLVH+GVIFPPPY PHGVKMLY G+ V LTPEQEEVATM
Sbjct: 340  SQYSKSTKMLPGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATM 399

Query: 1827 FAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMST 1648
            FAVM DTDY  KPKF ENF  DWR +LGKNHVI+  E CDF PIY+WHQ +KEKKKQMS+
Sbjct: 400  FAVMLDTDYMQKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSS 459

Query: 1647 DEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPRD 1468
            +EKKA+KEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI+P D
Sbjct: 460  EEKKALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSD 519

Query: 1467 ITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQS 1288
            ITINIGKD PIPECPIPGE WKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQS
Sbjct: 520  ITINIGKDVPIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQS 579

Query: 1287 DKEKYEKARLLKDYIHNIRANYTKDFVSKDISKRQIAVATYLIDKLALRAGNEKDDDEAD 1108
            DKEKYEKAR LKDYIH+IRA YTKDFVS+D ++RQIAVATYLIDKLALRAGNEKDDDEAD
Sbjct: 580  DKEKYEKARKLKDYIHSIRAAYTKDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEAD 639

Query: 1107 TVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAIGLFKSGKKDGEDLF 928
            TVGCCTLKV NV  +PPN+L+FDFLGKDSI+Y NTVEVELPVYKAIG F++GKK  +DLF
Sbjct: 640  TVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLF 699

Query: 927  DKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDVAEKIVIYQHANKEV 748
            DKLDT KLNAHLKELMPGLTAKVFRTYNASITLDGML+  T  GDVA KI +YQ ANKEV
Sbjct: 700  DKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEV 759

Query: 747  AIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGKPPL-KDADGKQKKN 571
            AIICNHQR+VSK+H+AQMSRL+EK+++LK V+ +L+ DL RAKKGKPPL KD+DGK+K+N
Sbjct: 760  AIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRN 819

Query: 570  LAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIE 391
            LAPEALERK+AQTNAKIEKMERDM+TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIE
Sbjct: 820  LAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE 879

Query: 390  KIFNKSLLAKFAWAMDVDPSFRF 322
            KIFNKSLLAKFAWAMDVDP FRF
Sbjct: 880  KIFNKSLLAKFAWAMDVDPEFRF 902


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score = 1066 bits (2758), Expect = 0.0
 Identities = 579/936 (61%), Positives = 650/936 (69%), Gaps = 39/936 (4%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQN-DGLSGRHPRDAV 2836
            MAV+ C              P++FKR+K   KQNQ NSE KK S Q  DG S  H  D  
Sbjct: 1    MAVEACTT-NLMEDMEDDGGPVIFKRSKPAPKQNQANSEKKKLSLQKQDGQSAVHTSDVR 59

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIADKSK-----HSSGKSAGVNDAGX 2671
              NG+++S+ K ++  S K    K  + + K S S A  S       +S  SA       
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 119

Query: 2670 XXXXXXXXXXNVD-------------SEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLX 2530
                       ++             SE SDD+KPLS R     ++  KSN      G  
Sbjct: 120  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSART-FGCSSKGKSNHANKEGGDS 178

Query: 2529 XXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSC-GPSSVKKYDSDEEKPLASKIL 2353
                     E                     RF  KS  G S+ K YDSDE+KPLA+K+ 
Sbjct: 179  CSIRRPVIEESEDSEDEKPLSC---------RFTSKSSLGESTSKSYDSDEKKPLAAKVQ 229

Query: 2352 QNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTD 2173
            QNGS  RD  + KS  + NKRP  +  +  QS+VKKPKLS             K E K +
Sbjct: 230  QNGSASRDGPMNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAE 289

Query: 2172 DDDDYVPIGQRMKKLTVPDNKSQ------------------SAXXXXXXXXXXXXXXXXX 2047
            DDDD +P+ QR KK     +K +                  S                  
Sbjct: 290  DDDDNIPLSQRGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSS 349

Query: 2046 XXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQP 1867
                               S+KVPPGSGEGQKWTTLVH+GVIFPPPYKPHGVKMLY  QP
Sbjct: 350  LKKVNKNSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQP 409

Query: 1866 VQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEW 1687
            + LTPEQEEVATMFAVM DTDY  KP F ENF +DW+ ILGKNH+I+  E CDF PIYEW
Sbjct: 410  ITLTPEQEEVATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEW 469

Query: 1686 HQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 1507
            HQ+EKEKKKQM+T+EKKA+KEEKL+QEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP
Sbjct: 470  HQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 529

Query: 1506 KMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKY 1327
            KMGKLK+RIRPRDITINIGKDAPIPECPIPGERWKEV++ NTVTWLA+WNDPIN KEFKY
Sbjct: 530  KMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKY 589

Query: 1326 VFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVS-KDISKRQIAVATYLIDKL 1150
            VFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDF + KD  K+QIAVATYLIDKL
Sbjct: 590  VFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKL 649

Query: 1149 ALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAI 970
            ALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+FDFLGKDSIRY N V+VE  V+KAI
Sbjct: 650  ALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAI 709

Query: 969  GLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDV 790
              F+SGK+  EDLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD MLS ETK G+V
Sbjct: 710  QQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEV 769

Query: 789  AEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGK 610
            AE +V+YQHANKEVAIICNHQR+VSKSH+AQMSRL+EK+DELK  ++ELKTDL+RAKKGK
Sbjct: 770  AENVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGK 829

Query: 609  PPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRI 430
            PP K ADGK K+NL PEALERKI QTNAKIEKMERD  TKEDLKTVALGTSKINYLDPRI
Sbjct: 830  PPTKGADGKAKRNLNPEALERKITQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRI 889

Query: 429  SVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            +VAWCKRHEVPIEKIFNKSLLAKFAW+MDVDPSFRF
Sbjct: 890  TVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 925


>ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|567920950|ref|XP_006452481.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555705|gb|ESR65719.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555707|gb|ESR65721.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 902

 Score = 1066 bits (2756), Expect = 0.0
 Identities = 580/923 (62%), Positives = 656/923 (71%), Gaps = 26/923 (2%)
 Frame = -3

Query: 3012 MAVDTCVKP-KFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQN-DGLSGRHPRDA 2839
            MAV+   KP + +      D P VFKRN   S+QN  N E+K+PSS   +G +   P+D 
Sbjct: 1    MAVEASSKPSRVYDFDDDEDGPAVFKRNTAASRQNLANPEVKRPSSSTANGQNSNAPKDK 60

Query: 2838 VSPNGQN--------------TSSHK--------RKVVSSTKALTTKFTIGNLKESTSIA 2725
             + +                 TSS K        R  V S      K  + N KES+ + 
Sbjct: 61   TTVSSSKVLPVKSPPPSQKATTSSAKASPLKSPMRSPVKSPVRSPVKSPVANSKESSPLD 120

Query: 2724 DKSKHSSGKSAGVNDAGXXXXXXXXXXXNVDSEDSDDDKPLSYRLPIASTTLPKSNSPRV 2545
            D+ K     +A                   D  DS+DDKPLS RL        K N+  V
Sbjct: 121  DRLKQLPQHNALA--VVKKEEIKDGNGLKSDDNDSEDDKPLSARL--------KGNTKNV 170

Query: 2544 SKGLXXXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSCGPSSVKKYDSDEEKPLA 2365
            ++G+         SE   VN               SRF   + G S  K  DSDE+KPLA
Sbjct: 171  NQGIGASKADAAISE---VNVKTDPEDSDDEVPLSSRFPKSNAGTSGAKPIDSDEKKPLA 227

Query: 2364 SKILQNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAE 2185
            SK+ QNGS  R+++  KS  V  KRPL   S+S  S+ KKPK+SD            K E
Sbjct: 228  SKVQQNGSTSRETQQ-KSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVE 286

Query: 2184 SKTDDDDDYVPIGQRMKKLTVPDNKSQSAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2005
             K DDDD ++PI QRMK      N + S                                
Sbjct: 287  KKADDDD-HIPISQRMK------NSAPSVKKSVTNTAKATKSVSSSSKKINKKTKKVIKN 339

Query: 2004 XXXXXSTKVPPGSGEGQK-WTTLVHSGVIFPPPYKPHGVKMLYNGQPVQLTPEQEEVATM 1828
                 STK+ PGSG+GQK WTTLVH+GVIFPPPY PHGVKMLY G+ V LTPEQEEVATM
Sbjct: 340  SQYSKSTKMLPGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATM 399

Query: 1827 FAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMST 1648
            FAVM DTDY  KPKF ENF  DWR +LGKNHVI+  E CDF PIY+WHQ +KEKKKQMS+
Sbjct: 400  FAVMLDTDYMQKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSS 459

Query: 1647 DEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPRD 1468
            +EKKA+KEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI+P D
Sbjct: 460  EEKKALKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSD 519

Query: 1467 ITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQS 1288
            ITINIGKD PIPECPIPGE WKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQS
Sbjct: 520  ITINIGKDVPIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQS 579

Query: 1287 DKEKYEKARLLKDYIHNIRANYTKDFVSKDISKRQIAVATYLIDKLALRAGNEKDDDEAD 1108
            D+EKYEKAR LKDYIH+IRA YTKDFVS+D ++RQIAVATYLIDKLALRAGNEKDDDEAD
Sbjct: 580  DREKYEKARKLKDYIHSIRAAYTKDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEAD 639

Query: 1107 TVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAIGLFKSGKKDGEDLF 928
            TVGCCTLKV NV  +PPN+L+FDFLGKDSI+Y NTVEVELPVYKAIG F++GKK  +DLF
Sbjct: 640  TVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLF 699

Query: 927  DKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDVAEKIVIYQHANKEV 748
            DKLDT KLNAHLKELMPGLTAKVFRTYNASITLDGML+  T  GDVA KI +YQ ANKEV
Sbjct: 700  DKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEV 759

Query: 747  AIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGKPPL-KDADGKQKKN 571
            AIICNHQR+VSK+H+AQMSRL+EK+++LK V+ +L+ DL RAKKGKPPL KD+DGK+K+N
Sbjct: 760  AIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRN 819

Query: 570  LAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIE 391
            LAPEALERK+AQTNAKIEKMERDM+TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIE
Sbjct: 820  LAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIE 879

Query: 390  KIFNKSLLAKFAWAMDVDPSFRF 322
            KIFNKSLLAKFAWAMDVDP FRF
Sbjct: 880  KIFNKSLLAKFAWAMDVDPEFRF 902


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score = 1061 bits (2744), Expect = 0.0
 Identities = 577/938 (61%), Positives = 651/938 (69%), Gaps = 41/938 (4%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQND-GLSGRHPRDAV 2836
            MAV+ C  P         + P++FKR+   SKQNQ NSE KK S Q   G S  H  D  
Sbjct: 1    MAVEACT-PNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 59

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIADKSK-----HSSGKSAGVNDAGX 2671
              NG+++S+ K ++  S K    K  + + K S S A  S       +S  SA       
Sbjct: 60   PANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 119

Query: 2670 XXXXXXXXXXNVD-------------SEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLX 2530
                       ++             SE SDD+KPLS R     ++  KSN      G  
Sbjct: 120  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSART-FGCSSKGKSNHANKEGGDS 178

Query: 2529 XXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSC-GPSSVKKYDSDEEKPLASKIL 2353
                     E                     RF  KS  G S+ K YDSDE+KPLA+K+ 
Sbjct: 179  CSIRRRVIEESEDSEDEKPLSR---------RFTSKSSLGESTSKSYDSDEKKPLAAKVQ 229

Query: 2352 QNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSD--AXXXXXXXXXXXKAESK 2179
            QNGS  RD  + KS  + NKRP  +V +  QS+VKKPKLS               + E K
Sbjct: 230  QNGSVSRDGPMNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPK 289

Query: 2178 TDDDDDYVPIGQRMKKLTVPDNKSQ------------------SAXXXXXXXXXXXXXXX 2053
             +DDDD +P+ QR KK     +K +                  S                
Sbjct: 290  AEDDDDNIPLSQRGKKSQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVS 349

Query: 2052 XXXXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNG 1873
                                 S+KVPPGSGEGQKWTTLVH+GVIFPPPY PHGVKMLY  
Sbjct: 350  PSLKKVNKNSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKR 409

Query: 1872 QPVQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIY 1693
            QP+ LTPEQEEVATMFAVM DTDY  KP+F ENF +DW+ +LGKNH I+  E CDF PIY
Sbjct: 410  QPITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIY 469

Query: 1692 EWHQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGE 1513
            EWHQ+EKEKKKQM+T+EKKA+KE+KL+QEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGE
Sbjct: 470  EWHQQEKEKKKQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGE 529

Query: 1512 HPKMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEF 1333
            HPKMGKLK+RIRPRDITINIGKDAPIPECPIPGERWKEV++DNTVTWLAFW DPIN KEF
Sbjct: 530  HPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEF 589

Query: 1332 KYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVS-KDISKRQIAVATYLID 1156
            KYVFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDF + KD  K+QIAVATYLID
Sbjct: 590  KYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLID 649

Query: 1155 KLALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYK 976
            KLALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+FDFLGKDSIRY N V+VE  V+K
Sbjct: 650  KLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFK 709

Query: 975  AIGLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAG 796
            AI  F+SGK+  EDLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD MLS ETK G
Sbjct: 710  AIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGG 769

Query: 795  DVAEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKK 616
            +VAEK+V+YQHANKEVAIICNHQR+VSKSH+AQMSRL+EK+DELK  M+ELKTDL+R KK
Sbjct: 770  EVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKK 829

Query: 615  GKPPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDP 436
            GKPP K ADGK K+NL PEALERK+AQ NAKIEKMERD  TKEDLKTVALGTSKINYLDP
Sbjct: 830  GKPPSKGADGKPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINYLDP 889

Query: 435  RISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            RI+VAWCKRHEVPIEKIFNKSLLAKFAW+MDVDPSFRF
Sbjct: 890  RITVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 927


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score = 1054 bits (2726), Expect = 0.0
 Identities = 571/929 (61%), Positives = 645/929 (69%), Gaps = 39/929 (4%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQND-GLSGRHPRDAV 2836
            MAV+ C            + P++FKR+   SKQNQ NSE KK S Q   G S  H  D  
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQRHVGQSAVHTSDVR 60

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIADKSKHSSG-----KSAGVNDAGX 2671
              NG+N+S+ K ++  S K    K  + + K S S A  S  +S       SA       
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAGANSKPSASATSTAK 120

Query: 2670 XXXXXXXXXXNVD-------------SEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLX 2530
                       ++             SE SDD+KPLS R     ++  KSN      G  
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSART-FGCSSKGKSNHANKEGGDS 179

Query: 2529 XXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSC-GPSSVKKYDSDEEKPLASKIL 2353
                     E                     RF  KS  G S+ K YDSDE+KPLA+K+ 
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSR---------RFTSKSSLGESTSKSYDSDEKKPLAAKVQ 230

Query: 2352 QNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTD 2173
             NGS  RDS + KS  + NKRP  +V +  QS++KKPKLS             K E K +
Sbjct: 231  PNGSASRDSPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAE 290

Query: 2172 DDDDYVPIGQRMKKLTVPDNKSQ------------------SAXXXXXXXXXXXXXXXXX 2047
            DDDD +P+ QR KK     +K +                  S                  
Sbjct: 291  DDDDNIPLSQRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPS 350

Query: 2046 XXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQP 1867
                               S+KVPPGSGEGQKWTTLVH+GVIFPPPYKPHGVKMLY  QP
Sbjct: 351  LKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQP 410

Query: 1866 VQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEW 1687
            + LTPEQEEVATMFAVM DTDY  KP+F ENF +DW+ +LGKNH I+  E CDF PIYEW
Sbjct: 411  ITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEW 470

Query: 1686 HQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 1507
            HQ+EKEKKKQM+T+EKKA+KEEKL+QEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP
Sbjct: 471  HQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 530

Query: 1506 KMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKY 1327
            KMGKLK+RIRPRDITINIGKDAPIPECPIPGERWKEV++DNTVTWLA+WNDPIN KEFKY
Sbjct: 531  KMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKY 590

Query: 1326 VFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFV-SKDISKRQIAVATYLIDKL 1150
            VFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDF  +KD  K+QIAVATYLIDKL
Sbjct: 591  VFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKL 650

Query: 1149 ALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAI 970
            ALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+FDFLGKDSIRY N V+VE  V+KAI
Sbjct: 651  ALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAI 710

Query: 969  GLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDV 790
              F+SGK+  EDLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD MLS +T  G+V
Sbjct: 711  QQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEV 770

Query: 789  AEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGK 610
            AEK+V+YQHANKEVAIICNHQR+VSKSH+AQMSRL+EK+DELK  ++ELKTDL+RAKKGK
Sbjct: 771  AEKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGK 830

Query: 609  PPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRI 430
            P  K ADGK K+NL PEALERKIAQTNAKIEKMERD  TKEDLKTVALGTSKINYLDPRI
Sbjct: 831  PLSKGADGKPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRI 890

Query: 429  SVAWCKRHEVPIEKIFNKSLLAKFAWAMD 343
            +VAWCKRHEVPIEKIFNKSLLAKFAWAM+
Sbjct: 891  TVAWCKRHEVPIEKIFNKSLLAKFAWAMN 919


>ref|XP_002300344.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222847602|gb|EEE85149.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 877

 Score = 1054 bits (2726), Expect = 0.0
 Identities = 575/890 (64%), Positives = 638/890 (71%), Gaps = 13/890 (1%)
 Frame = -3

Query: 2952 PIVFKRN-KTISKQNQLNSEIKKPSSQNDGLSGRH----------PRDAVSPNGQNTSSH 2806
            PIVFKR   + SKQNQLN E KKPSS +   +G+           P    SP   +T S 
Sbjct: 24   PIVFKRGGNSTSKQNQLNPEAKKPSSSSQNSNGQSLNLQKGKSPIPSSNASPMKSSTGSP 83

Query: 2805 KRKVVSSTKALTTKFTIGNLKESTSIADKSKHSSGKSAGVNDAGXXXXXXXXXXXNVDSE 2626
            K    SS KA   K  +   +  TS  D+ K +S +   V++A             VD E
Sbjct: 84   KASA-SSAKASPLKSPLTYTRALTSSNDQLKQASKQV--VSNA-----VKEETKSIVDDE 135

Query: 2625 DSDDDKPLSYRLPIASTTLPKSNSPRVSKGLXXXXXXXXXSEKAKVNXXXXXXXXXXXXX 2446
            DS+DDKPLS R+        K ++  V+KG+                             
Sbjct: 136  DSEDDKPLSSRI--------KGSTNNVNKGVTAPAHVKDEPSD------------DDEVP 175

Query: 2445 XXSRFKLKS-CGPSSVKKYDSDEEKPLASKILQNGSNKRDSELVKSHKVLNKRPLSDVST 2269
              SRF +KS  G SS K   S E +P  SK   NGS K D +  KS  V  KRP+ +   
Sbjct: 176  LSSRFAMKSNAGTSSSKSIRSSEIRPFPSKSQLNGSTKNDKQQ-KSSVVPTKRPMDNKVP 234

Query: 2268 SVQSAVKKPKLSDAXXXXXXXXXXXKAESKTDDDDDYVPIGQRMKKLTVPDNKSQSAXXX 2089
            S  S+ KKPKL DA           K E K DDDD ++ I QRMKK     NKS  A   
Sbjct: 235  SNHSSAKKPKLLDACTTTKVKQVTVKVEQKADDDD-HLTISQRMKKADSSANKSSFAKKK 293

Query: 2088 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQK-WTTLVHSGVIFPP 1912
                                              TKV PGS +GQK WTTLVH+GVIFPP
Sbjct: 294  VTKVVSSSLKKTTQKNKKQMKNSKYSKS------TKVQPGSSDGQKKWTTLVHNGVIFPP 347

Query: 1911 PYKPHGVKMLYNGQPVQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHV 1732
            PYKPHGVK+LY G+P+ LTPEQEEVATMFAVMKDTDY  KP+F +NF  DWR +LGKNHV
Sbjct: 348  PYKPHGVKILYKGKPIDLTPEQEEVATMFAVMKDTDYVQKPQFRQNFWNDWRKLLGKNHV 407

Query: 1731 IKKFELCDFTPIYEWHQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNF 1552
            I+K + CDF PIYEWHQ+EKEKKKQMST+EKK +KEEKLKQEEKYMWAIV+GVKEKVGNF
Sbjct: 408  IQKLDDCDFNPIYEWHQQEKEKKKQMSTEEKKVLKEEKLKQEEKYMWAIVNGVKEKVGNF 467

Query: 1551 RVEPPGLFRGRGEHPKMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTW 1372
            RVEPPGLFRGRGEHPKMGKLK RIRP DITINIGKDAPIPECPIPGERWKEVKHDNTVTW
Sbjct: 468  RVEPPGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPECPIPGERWKEVKHDNTVTW 527

Query: 1371 LAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVSKDIS 1192
            LAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIHNIRA YTKDF SKDI+
Sbjct: 528  LAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIRAAYTKDFASKDIT 587

Query: 1191 KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRY 1012
            KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV  +PPN+L+FDFLGKDSIRY
Sbjct: 588  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLGKDSIRY 647

Query: 1011 FNTVEVELPVYKAIGLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASIT 832
             NTVEVELPVYKAIG F+  KK  +DLFD LDT+KLNAHLKELMPGLTAKVFRTYNASIT
Sbjct: 648  ENTVEVELPVYKAIGHFQVAKKQTDDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASIT 707

Query: 831  LDGMLSNETKAGDVAEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVM 652
            LD  L  ET+ GDVAEKIVIY  ANK+VAIICNHQR++SKSH AQMSRL+EK++ELK+ +
Sbjct: 708  LDEKLYEETEDGDVAEKIVIYNQANKQVAIICNHQRTISKSHDAQMSRLTEKIEELKSTL 767

Query: 651  DELKTDLTRAKKGKPPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTV 472
             ELKTDL RAKKGKPPLK ADGKQK++L PEA+E+KIA TN KIEKME  M+TKEDLKTV
Sbjct: 768  KELKTDLDRAKKGKPPLKGADGKQKRSLTPEAIEKKIATTNQKIEKMEMAMKTKEDLKTV 827

Query: 471  ALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            ALGTSKINYLDPRI+VAWCKRHEVPI+KIFNKSLLAKF WAMDVDP FRF
Sbjct: 828  ALGTSKINYLDPRITVAWCKRHEVPIDKIFNKSLLAKFTWAMDVDPQFRF 877


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score = 1054 bits (2725), Expect = 0.0
 Identities = 571/929 (61%), Positives = 645/929 (69%), Gaps = 39/929 (4%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQND-GLSGRHPRDAV 2836
            MAV+ C            + P++FKR+   SKQNQ NSE KK S Q   G S  H  D  
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIADKSK-----HSSGKSAGVNDAGX 2671
              NG+N+S+ K ++  S K    K  + + K S S A  S       +S  SA       
Sbjct: 61   PANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAK 120

Query: 2670 XXXXXXXXXXNVD-------------SEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLX 2530
                       ++             SE SDD+KPLS R     ++  KSN      G  
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSART-FGCSSKGKSNHANKEGGDS 179

Query: 2529 XXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSC-GPSSVKKYDSDEEKPLASKIL 2353
                     E                     RF  KS  G S+ K YDSDE+KPLA+K+ 
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSR---------RFTSKSSLGESTSKSYDSDEKKPLAAKVQ 230

Query: 2352 QNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTD 2173
             NGS  RDS + KS  + NKRP  +V +  QS++KKPKLS             K E K +
Sbjct: 231  PNGSASRDSPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAE 290

Query: 2172 DDDDYVPIGQRMKKLTVPDNKSQ------------------SAXXXXXXXXXXXXXXXXX 2047
            DDDD +P+ QR KK     +K +                  S                  
Sbjct: 291  DDDDNIPLSQRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPS 350

Query: 2046 XXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQP 1867
                               S+KVPPGSGEGQKWTTLVH+GVIFPPPYKPHGVKMLY  QP
Sbjct: 351  LKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQP 410

Query: 1866 VQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEW 1687
            + LTPEQEEVATMFAVM DTDY  KP+F ENF +DW+ +LGKNH I+  E CDF PIYEW
Sbjct: 411  ITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEW 470

Query: 1686 HQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 1507
            HQ+EKEKKKQM+T+EKKA+KEEKL+QEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP
Sbjct: 471  HQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 530

Query: 1506 KMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKY 1327
            KMGKLK+RIRPRDITINIGKDAPIPECPIPGERWKEV++DNTVTWLA+WNDPIN KEFKY
Sbjct: 531  KMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKY 590

Query: 1326 VFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFV-SKDISKRQIAVATYLIDKL 1150
            VFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDF  +KD  K+QIAVATYLIDKL
Sbjct: 591  VFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKL 650

Query: 1149 ALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAI 970
            ALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+FDFLGKDSIRY N V+VE  V+KAI
Sbjct: 651  ALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAI 710

Query: 969  GLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDV 790
              F+SGK+  EDLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD MLS +T  G+V
Sbjct: 711  HQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEV 770

Query: 789  AEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGK 610
            AEK+V+YQHANKEVAIICNHQR+VSKSH+AQMSRL+EK+DELK  ++ELKTDL+RAKKGK
Sbjct: 771  AEKVVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGK 830

Query: 609  PPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRI 430
            P  K ADGK K+NL PEALERKIAQTNAKIEKMERD  TKEDLKTVALGTSKINYLDPRI
Sbjct: 831  PLSKGADGKPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRI 890

Query: 429  SVAWCKRHEVPIEKIFNKSLLAKFAWAMD 343
            +VAWCKRHEVPIEKIFNKSLLAKFAWAM+
Sbjct: 891  TVAWCKRHEVPIEKIFNKSLLAKFAWAMN 919


>ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis sativus]
            gi|449503189|ref|XP_004161878.1| PREDICTED: DNA
            topoisomerase 1-like [Cucumis sativus]
          Length = 889

 Score = 1051 bits (2717), Expect = 0.0
 Identities = 575/913 (62%), Positives = 656/913 (71%), Gaps = 16/913 (1%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQN-DGLSGRHPRDAV 2836
            MAV+T  K   F      + PIVFKR    S+QNQL+SEIK   +Q    L GR   D  
Sbjct: 1    MAVETFGKAPMFDDDDEDNMPIVFKRTSA-SRQNQLDSEIKHSQAQRLSKLPGRQGSDLC 59

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIA-----DKSKHSSGKSAGVNDA-- 2677
            S NGQ++++ KR + S  K    +  IG+ K S S        KS  +S K++   D+  
Sbjct: 60   STNGQSSNNQKR-MTSLPKTSPMRSEIGSQKASRSSPIPEPLTKSLGTSLKASHSMDSRP 118

Query: 2676 -----GXXXXXXXXXXXNVDSEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLXXXXXXX 2512
                             + ++ DS+DDKPLS RL        K N  + +KGL       
Sbjct: 119  KSLVNAVVKEENVSINPSQENSDSEDDKPLSIRL--------KGNPNQPNKGLVSTVP-- 168

Query: 2511 XXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSCGPSSVKKYDSDEEKPLASKILQNGSNKR 2332
                K KV                 + K  S G    K++  DE+KPL  K+ QNGS  R
Sbjct: 169  ----KNKVKKSLADSDDEVPLSSKFQMKHAS-GVLGSKQHGFDEKKPLVPKVHQNGSTSR 223

Query: 2331 DSELVKSHKVLNKRPL--SDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTDDDDDY 2158
            D +L K   + +KRPL   D  +  Q   KKPKL+D+           KA+ + DDDDD 
Sbjct: 224  D-KLQKPAVLSSKRPLPNEDSHSPSQFPTKKPKLTDSSSPLNSKLVSLKAKQEVDDDDDD 282

Query: 2157 VPIGQRMKKLTVPDNKSQSAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSTKV 1978
            +PI QRMKK++   NKS S+                                     TK+
Sbjct: 283  IPISQRMKKVSATVNKSSSSKPTISKVVSSSIKKTFKKSKKPVKKSKYVKS------TKL 336

Query: 1977 PPGSGEGQK-WTTLVHSGVIFPPPYKPHGVKMLYNGQPVQLTPEQEEVATMFAVMKDTDY 1801
             P +G+GQK WTTLVH+GVIFPPPY+ HGVKMLY G+PV LTP QEEVATMFAVMKDTDY
Sbjct: 337  LPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPPQEEVATMFAVMKDTDY 396

Query: 1800 ATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSTDEKKAVKEE 1621
              KPKF ENF  DWR +LGKNHVI+  + CDFTPIY+W+Q EKEKKKQM+T+EKKAVKEE
Sbjct: 397  MLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQMEKEKKKQMTTEEKKAVKEE 456

Query: 1620 KLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPRDITINIGKDA 1441
            KLKQEEKYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRI P DITINIGK A
Sbjct: 457  KLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRICPSDITINIGKGA 516

Query: 1440 PIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 1261
            PIPECPIPGERWKEV+HDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR
Sbjct: 517  PIPECPIPGERWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKAR 576

Query: 1260 LLKDYIHNIRANYTKDFVSKDISKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 1081
            +LKDYI NIR  YTKDF SKD ++RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 577  MLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 636

Query: 1080 ENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAIGLFKSGKKDGEDLFDKLDTNKLN 901
            ENV  VPPN L+F+FLGKDSIRY NTVEVELPV+KAI  F+SGK   +DLFDKLDT+KLN
Sbjct: 637  ENVKAVPPNLLEFNFLGKDSIRYENTVEVELPVFKAITQFQSGKSGTDDLFDKLDTSKLN 696

Query: 900  AHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDVAEKIVIYQHANKEVAIICNHQRS 721
            AHLK+LMPGLTAKVFRTYNASITLD ML+  TK G+V+EKIV YQHANKEVAIICNHQR+
Sbjct: 697  AHLKDLMPGLTAKVFRTYNASITLDDMLNRGTKNGEVSEKIVTYQHANKEVAIICNHQRT 756

Query: 720  VSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGKPPLKDADGKQKKNLAPEALERKI 541
            VSKSH AQM+RL+EK+ EL+ ++ ELK DL RAKKGKPPLK +DGKQK+NL PEALE+KI
Sbjct: 757  VSKSHGAQMTRLNEKISELRDILKELKIDLDRAKKGKPPLKGSDGKQKRNLTPEALEKKI 816

Query: 540  AQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAK 361
            +QTNAKIEK+ERDM+TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAK
Sbjct: 817  SQTNAKIEKIERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAK 876

Query: 360  FAWAMDVDPSFRF 322
            FAWAMDVDP FRF
Sbjct: 877  FAWAMDVDPDFRF 889


>ref|XP_002317355.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222860420|gb|EEE97967.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 860

 Score = 1049 bits (2713), Expect = 0.0
 Identities = 574/887 (64%), Positives = 635/887 (71%), Gaps = 10/887 (1%)
 Frame = -3

Query: 2952 PIVFKRN-KTISKQNQLNSEIKKPSSQNDGLSGRHPRDAVSPNGQNTSSHKRKV-VSSTK 2779
            PIVFKR   + SKQNQ N E KKPSS +            + NGQ+ ++HK K  +SS+ 
Sbjct: 23   PIVFKRGGNSTSKQNQPNLEAKKPSSSSQ-----------NSNGQSLNAHKGKSPISSSN 71

Query: 2778 ALTTKFTIGNLKESTSIADKSK------HSSGKSAGVNDAGXXXXXXXXXXXNVDSEDSD 2617
            A   K  IG+ K S S A  S       +S   S+ +                VD +DS+
Sbjct: 72   ASPVKSPIGSPKASASSAKASPMKPPVTYSRVPSSSI-------AVKEETKPIVDDDDSE 124

Query: 2616 DDKPLSYRLPIASTTLPKSNSPRVSKGLXXXXXXXXXSEKAKVNXXXXXXXXXXXXXXXS 2437
            DDKPLS R         K ++   +KG+            A+V                 
Sbjct: 125  DDKPLSSRF--------KGSTNNANKGVTVP---------ARVKDEHSDDDEVPLSS--- 164

Query: 2436 RFKLKS-CGPSSVKKYDSDEEKPLASKILQNGSNKRDSELVKSHKVLNKRPLSDVSTSVQ 2260
            RF  KS  G SS K   S E+  L SKI  NGS  +D +  KS  V  KRP+ +   S Q
Sbjct: 165  RFAAKSNAGSSSCKTISSSEKILLVSKIQLNGSTAKDKQQ-KSSAVPTKRPMDNKVPSNQ 223

Query: 2259 SAVKKPKLSDAXXXXXXXXXXXKAESKTDDDDDYVPIGQRMKKLTVPDNKSQSAXXXXXX 2080
            S  KKPKLSDA            AE K DDDD ++ I QRMKK +   NKS S       
Sbjct: 224  SFAKKPKLSDASTTKQVTVK---AELKADDDD-HLTISQRMKKASSSSNKSLSVKQNVTK 279

Query: 2079 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQK-WTTLVHSGVIFPPPYK 1903
                                           TKV PGS +GQK W TLVH+GVIFPPPYK
Sbjct: 280  VVSFSSKKTTKNNKKQMQNSKYSKS------TKVQPGSSDGQKKWKTLVHNGVIFPPPYK 333

Query: 1902 PHGVKMLYNGQPVQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKK 1723
            PHGVKMLY G+PV LTPEQEEVATMFAVMKDT+Y  KP+F++NF  DWR +LGKNHVI+K
Sbjct: 334  PHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTEYVQKPQFLQNFWNDWRTLLGKNHVIQK 393

Query: 1722 FELCDFTPIYEWHQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVE 1543
             E CDF PIYEWHQ+EKEKKKQMST+EKKAV+EEKLKQEE YMWAIV+GVKEKVGNFRVE
Sbjct: 394  LEACDFNPIYEWHQKEKEKKKQMSTEEKKAVREEKLKQEEMYMWAIVNGVKEKVGNFRVE 453

Query: 1542 PPGLFRGRGEHPKMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAF 1363
            PPGLFRGRGEHPKMGKLK RIRP DITINIGKDAPIP+CPIPGERWKEVKHDNTVTWLAF
Sbjct: 454  PPGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPKCPIPGERWKEVKHDNTVTWLAF 513

Query: 1362 WNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVSKDISKRQ 1183
            WNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIHNIR  YTKDF SKDI+KRQ
Sbjct: 514  WNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIRTAYTKDFASKDITKRQ 573

Query: 1182 IAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNT 1003
            IAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV  +PPN+L+FDFLGKDSIRY NT
Sbjct: 574  IAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLGKDSIRYENT 633

Query: 1002 VEVELPVYKAIGLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDG 823
            VEVELPVYKAI  F+  KK  +DLFD LDT+KLNAHLKELMPGLTAKVFRTYNASITLD 
Sbjct: 634  VEVELPVYKAIRQFQVAKKPTDDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDE 693

Query: 822  MLSNETKAGDVAEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDEL 643
             L  ET+ GDVAEK VIY  ANK+VAIICNHQR++SKSH AQMSRL+EK++ELK  + E 
Sbjct: 694  KLYEETEDGDVAEKFVIYNQANKQVAIICNHQRTISKSHDAQMSRLTEKLEELKGTLKEF 753

Query: 642  KTDLTRAKKGKPPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALG 463
            KTDL RAKKGKPPLKDADGKQK+NL PEA+E+KIA TN KIEKME  M+TKEDLKTVALG
Sbjct: 754  KTDLDRAKKGKPPLKDADGKQKRNLTPEAIEKKIATTNQKIEKMELSMKTKEDLKTVALG 813

Query: 462  TSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            TSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAKF WAMDVDP FRF
Sbjct: 814  TSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPQFRF 860


>emb|CBI28783.3| unnamed protein product [Vitis vinifera]
          Length = 724

 Score = 1044 bits (2700), Expect = 0.0
 Identities = 548/772 (70%), Positives = 601/772 (77%), Gaps = 1/772 (0%)
 Frame = -3

Query: 2634 DSEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLXXXXXXXXXSEKAKVNXXXXXXXXXX 2455
            +SEDS+DDKPLS +L   S  LPK NS  V KGL          +K KV+          
Sbjct: 15   ESEDSEDDKPLSAKL---SARLPKGNS-HVLKGLSSPVLQS---QKTKVDSSD------- 60

Query: 2454 XXXXXSRFKLKSCGPSSVKKYDSDEEKPLASKILQNGSNKRDSELVKSHKVLNKRPLSDV 2275
                                 DS++E PL  K LQ  S K  S    S K+L+ + LS  
Sbjct: 61   ---------------------DSEDEIPLLLK-LQLKSRKGAS----SSKLLDSKGLSSP 94

Query: 2274 STSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTDDDDDYVPIGQRMKKLTVP-DNKSQSA 2098
            ++S   + +K K+++              ++ +DD +D +P+  + +  TV  DNK  S 
Sbjct: 95   ASSRPQS-QKAKVNN--------------KNLSDDSEDEIPLSSKFRLKTVSSDNKKASK 139

Query: 2097 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIF 1918
                                                 TKVPP SGEGQKWTTL H+GVIF
Sbjct: 140  TKVIPSSRKKATKKAKKSKKLAKSSKYSKS-------TKVPPNSGEGQKWTTLEHNGVIF 192

Query: 1917 PPPYKPHGVKMLYNGQPVQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKN 1738
            PPPYKPHGVKMLYNG+PV LTPEQEEVATMFAVMKDTDYATKP+FIENFM DWR  LGKN
Sbjct: 193  PPPYKPHGVKMLYNGRPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRVRLGKN 252

Query: 1737 HVIKKFELCDFTPIYEWHQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVG 1558
            HVIKKFELCDFTPIYEWH++EKEKKKQM+T+EKKA+KEEKLKQE+KYMWA+VDGVKEKVG
Sbjct: 253  HVIKKFELCDFTPIYEWHEKEKEKKKQMTTEEKKALKEEKLKQEDKYMWAVVDGVKEKVG 312

Query: 1557 NFRVEPPGLFRGRGEHPKMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTV 1378
            NFRVEPPGLFRGRGEHPKMGKLK+RI P DITINIGK+AP+PECPIPGERWKEV+HDNTV
Sbjct: 313  NFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGKEAPVPECPIPGERWKEVRHDNTV 372

Query: 1377 TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVSKD 1198
            TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYI NIRA YTKDF +KD
Sbjct: 373  TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIQNIRATYTKDFTNKD 432

Query: 1197 ISKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSI 1018
              KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+LVPPN+L+FDFLGKDSI
Sbjct: 433  TMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNKLEFDFLGKDSI 492

Query: 1017 RYFNTVEVELPVYKAIGLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNAS 838
            RYFNTVEVELPVYKAIG FK+GK  G+DLFDKLDT+KLNAHLKELMPGLTAKVFRTYNAS
Sbjct: 493  RYFNTVEVELPVYKAIGQFKTGKSGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNAS 552

Query: 837  ITLDGMLSNETKAGDVAEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKA 658
            ITLD ML+ E + GD  EKIVIYQHANKEVAIICNHQRSVSKSH  QMSRLSEKM EL+ 
Sbjct: 553  ITLDEMLNREARGGDAMEKIVIYQHANKEVAIICNHQRSVSKSHDVQMSRLSEKMRELQG 612

Query: 657  VMDELKTDLTRAKKGKPPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLK 478
            V+DELKTDL RAKKGKPPLKD+DGK KKN+ PE LERKIAQTN KIEKMERDM+TKEDLK
Sbjct: 613  VLDELKTDLARAKKGKPPLKDSDGKPKKNMTPEVLERKIAQTNTKIEKMERDMKTKEDLK 672

Query: 477  TVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            TVALGTSKINYLDPRISVAWCKR EVPIEKIFNKSLLAKFAWAMDVDPSFRF
Sbjct: 673  TVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKSLLAKFAWAMDVDPSFRF 724


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score = 1044 bits (2699), Expect = 0.0
 Identities = 566/936 (60%), Positives = 647/936 (69%), Gaps = 39/936 (4%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQND-GLSGRHPRDAV 2836
            MAV+ C  P         + P++FKR+   SKQNQ NSE KK S Q   G S  H  D  
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIADKSK-----HSSGKSAGVNDAGX 2671
              NG+++S+ K ++  S +    K  + + K S S A  S       +S  SA       
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2670 XXXXXXXXXXNVD-------------SEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLX 2530
                       ++             SE SDD+KPL  R    S+   KSN      G  
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSK-GKSNHANKEGGDS 179

Query: 2529 XXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSC-GPSSVKKYDSDEEKPLASKIL 2353
                     E                     RF  KS  G S+ K YDSDE+KPLA+K+ 
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSR---------RFPSKSSLGESTSKSYDSDEKKPLATKVQ 230

Query: 2352 QNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTD 2173
            QNGS  RD  + KS  +LNKR   +V +  QS++KK KLS             K E K +
Sbjct: 231  QNGSASRDGPMNKSASLLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAAVKPEPKAE 290

Query: 2172 DDDDYVPIGQRMKKLTVPDNKSQ------------------SAXXXXXXXXXXXXXXXXX 2047
            DDDD +P+ QR KK     +K +                  S                  
Sbjct: 291  DDDDNIPLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPS 350

Query: 2046 XXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQP 1867
                               S+KVPPGSGEGQKWTTLVH+GV+F PPYKPHGVKMLY  QP
Sbjct: 351  LKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKXQP 410

Query: 1866 VQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEW 1687
            + LTPEQEEVATMFAVM DTDY TKP+F ENF +DW+ +LGKNH ++  E CDF PIYEW
Sbjct: 411  LTLTPEQEEVATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEW 470

Query: 1686 HQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 1507
            HQ+EKEK+KQM+T+EKKA+KEE+L+QEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP
Sbjct: 471  HQQEKEKRKQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 530

Query: 1506 KMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKY 1327
            KMGKLK+RIRPRDITINIGKDAPIPECPIPGERWKEV++DNTVTWLAFWNDPIN KE KY
Sbjct: 531  KMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDPINQKECKY 590

Query: 1326 VFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVS-KDISKRQIAVATYLIDKL 1150
            VFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDF + KD  K+QIAVATYLIDKL
Sbjct: 591  VFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKL 650

Query: 1149 ALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAI 970
            ALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+ DF+GKDSIRY N V+VE  V+KAI
Sbjct: 651  ALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAI 710

Query: 969  GLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDV 790
              F+SGK+   DLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD MLS ETK G V
Sbjct: 711  QQFRSGKEGCADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKV 770

Query: 789  AEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGK 610
            AEK+ +YQHANKEVAIICNHQR+VSKSH+AQMSRL+EK+DELK  ++ELKTDL+RAKKGK
Sbjct: 771  AEKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGK 830

Query: 609  PPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRI 430
            PP K ADG+ K+NL PE+LERKIAQTNAKIEKMERD +TKEDLK VAL TSKI+YLDPRI
Sbjct: 831  PPAKGADGEPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRI 890

Query: 429  SVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            +VAWCKRHEVPIEKIFNKSLLAKFAW+MDVDPSFRF
Sbjct: 891  TVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPSFRF 926


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score = 1035 bits (2675), Expect = 0.0
 Identities = 561/936 (59%), Positives = 643/936 (68%), Gaps = 39/936 (4%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQND-GLSGRHPRDAV 2836
            MAV+ C  P         + P++FKR+   SKQNQ NSE KK S Q   G S  H  D  
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIADKSK-----HSSGKSAGVNDAGX 2671
              NG+++S+ K ++  S +    K  + + K S S A  S       +S  SA       
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2670 XXXXXXXXXXNVD-------------SEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLX 2530
                       ++             SE SDD+KPL  R    S+   KSN      G  
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSK-GKSNHANKEGGDS 179

Query: 2529 XXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSC-GPSSVKKYDSDEEKPLASKIL 2353
                     E                     RF  KS  G S+ K +DSDE+KPLA+K+ 
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSR---------RFPSKSSLGESTSKSHDSDEKKPLAAKVQ 230

Query: 2352 QNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTD 2173
            QNGS  RD  + KS  + NKR   +V +  QS++KKPKLS             K E K +
Sbjct: 231  QNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSTITSISNKQAAVKPEPKAE 290

Query: 2172 DDDDYVPIGQRMKKLTVPDNKSQ------------------SAXXXXXXXXXXXXXXXXX 2047
            DDDD +P+ QR KK     +K +                  S                  
Sbjct: 291  DDDDNIPLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPS 350

Query: 2046 XXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQP 1867
                               S+KVPPGSGEGQKWTTLVH+GV+FPPPYKPHGVKMLY  QP
Sbjct: 351  LKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQP 410

Query: 1866 VQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEW 1687
            + LTPEQEEVATMFA M DTDY  KP+F ENF +DW+ ILGKNH I+  E CDF PIYEW
Sbjct: 411  LTLTPEQEEVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEW 470

Query: 1686 HQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 1507
            HQ+EKEKKKQM+T+EKKA+KEE+L+ EEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP
Sbjct: 471  HQQEKEKKKQMTTEEKKALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 530

Query: 1506 KMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKY 1327
            K+GKLK+RIRPRDITINIGKDAPIPECPIPGERWKEV++DNTVTWLA+WNDP+N KE KY
Sbjct: 531  KVGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKY 590

Query: 1326 VFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVS-KDISKRQIAVATYLIDKL 1150
            VFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDF + KD  K+Q+AVATYLIDKL
Sbjct: 591  VFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAVATYLIDKL 650

Query: 1149 ALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAI 970
            ALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+ DF+GKDSIRY N V+VE  V+KAI
Sbjct: 651  ALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAI 710

Query: 969  GLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDV 790
              F+SGK+  EDLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD MLS ETK G V
Sbjct: 711  QQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKV 770

Query: 789  AEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGK 610
            AEK+ +YQ ANKEVAIICNHQR+VSKSH+AQMSRL+EK+DELK  ++ELKTDL+RAKKGK
Sbjct: 771  AEKVGVYQRANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGK 830

Query: 609  PPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRI 430
            PP K  DG+ K+NL PEALERKIAQTNAKIEKMERD +TKEDLK VAL TSKI+YLDPRI
Sbjct: 831  PPSKGDDGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRI 890

Query: 429  SVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            +VAWCKR EVPIEK+FNKSLLAKFAWAMDVDPSFRF
Sbjct: 891  TVAWCKRQEVPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score = 1034 bits (2673), Expect = 0.0
 Identities = 559/936 (59%), Positives = 645/936 (68%), Gaps = 39/936 (4%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQND-GLSGRHPRDAV 2836
            MAV+ C            + P++FKR+   SKQNQ N+E KK S Q   G S  H  D  
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPTSKQNQANAEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIADKSK-----HSSGKSAGVNDAGX 2671
              NG+++S+ K ++  S +    K  + + K S S A  S       +S  SA       
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2670 XXXXXXXXXXNVD-------------SEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLX 2530
                       ++             SE SDD+KPL  R    S+ + KSN      G  
Sbjct: 121  QQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSS-MGKSNHANKEGGDS 179

Query: 2529 XXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSC-GPSSVKKYDSDEEKPLASKIL 2353
                     E                     RF  KS  G S+ K YDSDE+KPLA+K+ 
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSR---------RFPSKSSLGESTSKSYDSDEKKPLAAKVQ 230

Query: 2352 QNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTD 2173
            QNGS   +  + KS  + NKR   +V +  QS++KKPKLS             K E K +
Sbjct: 231  QNGSASPEGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAE 290

Query: 2172 DDDDYVPIGQRMKKLTVPDNKSQ------------------SAXXXXXXXXXXXXXXXXX 2047
            DDDD +P+ QR KK     +K +                  S                  
Sbjct: 291  DDDDNIPLSQRGKKSQTAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKKASTVVSTS 350

Query: 2046 XXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQP 1867
                               S+KVPPGSGEGQKWTTLVH+GV+FPPPYKPHGVKMLY  QP
Sbjct: 351  LKKVNKKSKKVIRKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQP 410

Query: 1866 VQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEW 1687
            + LTPEQEEVATMFAVM DTDY  KP+F ENF +DW+ ILGKNH I+  E CDF PIYEW
Sbjct: 411  LTLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEW 470

Query: 1686 HQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 1507
            HQ+EKEKKKQM+T+EKKA+KEE+L+QEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP
Sbjct: 471  HQQEKEKKKQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 530

Query: 1506 KMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKY 1327
            K+GKLK+RIRPRDITINIGKDAPIPECPIPGERWKEV++DNTVTWLA+WNDP+N KE KY
Sbjct: 531  KVGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNIKECKY 590

Query: 1326 VFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVS-KDISKRQIAVATYLIDKL 1150
            VFLAASS+LKGQS KEKYEKAR+LKDYIH IRA YTK F + KD  K+QIAVATYLIDKL
Sbjct: 591  VFLAASSTLKGQSVKEKYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAVATYLIDKL 650

Query: 1149 ALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAI 970
            ALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+ DF+GKDSIRY N V+VE  V+KAI
Sbjct: 651  ALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAI 710

Query: 969  GLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDV 790
              F+SGK+  EDLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD MLS ETK G +
Sbjct: 711  QQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKI 770

Query: 789  AEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGK 610
            AEK+ +YQHANKEVAIICNHQR+VSKSH+AQMSRL+EK+DELK  ++ELKTDL+RAKKGK
Sbjct: 771  AEKVAVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGK 830

Query: 609  PPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRI 430
            PP KDADG+ K+NL PE+LERKIAQTNAKIEKMERD +TKEDLK VAL TSKI+YLDPRI
Sbjct: 831  PPSKDADGEPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRI 890

Query: 429  SVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            +VAWCKR EVPIEK+FNKSLLAKFAWAMDVDPSFRF
Sbjct: 891  TVAWCKRQEVPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Mimulus guttatus]
          Length = 883

 Score = 1033 bits (2672), Expect = 0.0
 Identities = 561/900 (62%), Positives = 639/900 (71%), Gaps = 23/900 (2%)
 Frame = -3

Query: 2952 PIVFKRNKTISKQNQLNSEIKKPSSQNDGLSGRHPRDAVSPNGQNTSSHKRKVV------ 2791
            P+VFKR+ + SK  Q   E K  S +++   GR   D    NG N ++ K K V      
Sbjct: 22   PLVFKRSGSSSKPKQSEPENKLSSQKHNAQVGRQSSDVRPQNGTNANAQKGKSVTSSSSM 81

Query: 2790 ---------------SSTKALTTKFTIGNLKESTSIADKSKHSSGKSAGVNDAGXXXXXX 2656
                           SS KA   K    N K STS+  +SK  S KS    +        
Sbjct: 82   KPPVRPSLVSPKSSNSSVKASPIKSPDVNSKPSTSVVGESK--SVKSTIKEE-------- 131

Query: 2655 XXXXXNVDSEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLXXXXXXXXXSEKAKVNXXX 2476
                   +SEDS+DDKPLS R    S+   K+N  + +K               K +   
Sbjct: 132  -------NSEDSEDDKPLSARQVAGSS---KNNPNQTNK--------PNAPNLGKKSNVP 173

Query: 2475 XXXXXXXXXXXXSRFKLKS-CGPSSVKKYDSDEEKPL-ASKILQNGSNKRDSELVKSHKV 2302
                        ++F+ KS  G S+ +   S+E+KPL A K  +NGS   +    K   V
Sbjct: 174  KPEDSDDEIPLSAKFQGKSNAGASTSRSSHSEEKKPLVARKPDKNGSASTER---KPSTV 230

Query: 2301 LNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTDDDDDYVPIGQRMKKLTV 2122
            L KRP   V+++ QS +KKPKLSD+             E K +DD+D VP+ QR KK T 
Sbjct: 231  LQKRPADGVASAGQSNLKKPKLSDSLASKDKKASVKP-EVKAEDDEDLVPLSQRTKKSTT 289

Query: 2121 PDNKSQSAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTT 1942
            P+ K   A                                     +K+PP SG+GQKWTT
Sbjct: 290  PEKKPSPALKTNNKTNSKTNSKTNKKSKQVSKDNNYSKS------SKLPPSSGDGQKWTT 343

Query: 1941 LVHSGVIFPPPYKPHGVKMLYNGQPVQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTD 1762
            LVH+GVIFPPPYKPHGVKMLY G+PV LTPEQEEVATM+AVM +TDY  KP+F ENFMTD
Sbjct: 344  LVHNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVMLETDYLKKPQFKENFMTD 403

Query: 1761 WRPILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIV 1582
            W+ ILGKNHVI+  E CDFTPIYEWHQREKEKKKQMSTDEKKA+KEEKLK EEKYMWA++
Sbjct: 404  WKKILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKALKEEKLKLEEKYMWAVL 463

Query: 1581 DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPRDITINIGKDAPIPECPIPGERWK 1402
            DGV+EKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRP DITINIG+DAPIPECPI GERWK
Sbjct: 464  DGVREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGRDAPIPECPIEGERWK 523

Query: 1401 EVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANY 1222
            E++HDNTVTWLA+W+DPIN KEFKYVFLAASS+LKGQSDKEKYEKARLLKDYI  IR  Y
Sbjct: 524  EIRHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIQGIRTAY 583

Query: 1221 TKDFVSKDISKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQF 1042
            T+DFVSKD +K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+F
Sbjct: 584  TRDFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKF 643

Query: 1041 DFLGKDSIRYFNTVEVELPVYKAIGLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAK 862
            DFLGKDSIRY N VEVE  V+KAI  F+SGKK G+DLFDKLDT+KLNAHLKELMPGLTAK
Sbjct: 644  DFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAK 703

Query: 861  VFRTYNASITLDGMLSNETKAGDVAEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLS 682
            VFRTYNASITLD  LS ETK GD+AEK+V Y HANKEVAIICNHQR+VSK+H+AQM RL 
Sbjct: 704  VFRTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICNHQRTVSKTHSAQMLRLD 763

Query: 681  EKMDELKAVMDELKTDLTRAKKGKPPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERD 502
            EK+DELK V++ELKTDL RA+KGKP L  ADGK K+N+ PEALERKIAQT AKIEKMERD
Sbjct: 764  EKIDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEALERKIAQTTAKIEKMERD 823

Query: 501  MRTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
              TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEK+FNKSLL KF+WAMDVDPSFRF
Sbjct: 824  KETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLEKFSWAMDVDPSFRF 883


>ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinifera]
            gi|296082698|emb|CBI21703.3| unnamed protein product
            [Vitis vinifera]
          Length = 857

 Score = 1033 bits (2672), Expect = 0.0
 Identities = 580/907 (63%), Positives = 637/907 (70%), Gaps = 10/907 (1%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDE----PIVFKRNKTISKQNQLNSEIKKPSSQNDGLSGRHPR 2845
            MAV+ CV PK F      D+    P+VFKR+   S  N  NS +K  S     +SG    
Sbjct: 1    MAVEACVNPKMFNNEVDDDDDDERPLVFKRSSNSSASNN-NSRLKIQS-----ISGSKRP 54

Query: 2844 DAVSPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIADKSKHSSGKSAGVNDAGXXX 2665
            D    NGQ             K +            T          G+   V   G   
Sbjct: 55   DDAHSNGQKKD----------KGMAPPMPAKGSGRVTGSVKSPPQQVGRGVVV---GNSK 101

Query: 2664 XXXXXXXXNVDSEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLXXXXXXXXXSEKAKVN 2485
                     +DS DS+DDKPLS RL   S+ LPK      + GL          E+    
Sbjct: 102  VEAQNKKAELDS-DSEDDKPLSVRL---SSGLPKGKGSSNNVGLGRGGVGGVKKEE---- 153

Query: 2484 XXXXXXXXXXXXXXXSRFKLKSCGPSSVKKYDSDEEKPLASKILQNG-SNKRDSELVKSH 2308
                           S+F+LKS           DE+KPL  K+ QNG ++KRD    KS 
Sbjct: 154  ----DDDDDDKIPLSSKFQLKS-----------DEKKPLPLKVNQNGGTDKRD----KSP 194

Query: 2307 KVLNK-RPLSDVSTSV--QSAVKKPKLS-DAXXXXXXXXXXXKAESKT-DDDDDYVPIGQ 2143
             VLNK RPL  V++S+   S VKKPK+S  +           KAE K  DDDDD +PI Q
Sbjct: 195  TVLNKKRPLDGVNSSLGQSSLVKKPKISGQSAQPFKVTHATAKAEPKVEDDDDDDMPISQ 254

Query: 2142 RMKKLTVPDNKSQSAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSTKVPPGSG 1963
            RMKK       S +                                     STKVPP SG
Sbjct: 255  RMKKSGA---SSGNKPVPAKQKVTKVVSSTSFKKTKDIKSKKMEKNSKYSKSTKVPPSSG 311

Query: 1962 EGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQPVQLTPEQEEVATMFAVMKDTDYATKPKF 1783
            EGQKWTTLVH+GVIFPPPYKPHGVKMLY G+PV LTPEQEEVATMFAVM DTDY  K KF
Sbjct: 312  EGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMQKEKF 371

Query: 1782 IENFMTDWRPILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSTDEKKAVKEEKLKQEE 1603
             ENFM DWR ILGKNHVI++ + CDFTPIYEWHQ EKEKKKQMST+EKK +KEEKLK EE
Sbjct: 372  KENFMADWRKILGKNHVIQRLDDCDFTPIYEWHQEEKEKKKQMSTEEKKTLKEEKLKLEE 431

Query: 1602 KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPRDITINIGKDAPIPECP 1423
            KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRI P DITINIGK++ IPECP
Sbjct: 432  KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIHPSDITINIGKNSQIPECP 491

Query: 1422 IPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYI 1243
            IPGE WKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LK+YI
Sbjct: 492  IPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKNYI 551

Query: 1242 HNIRANYTKDFVSKDISKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLV 1063
             +IRA YTKDFVSKDI+KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV   
Sbjct: 552  KDIRATYTKDFVSKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVIPE 611

Query: 1062 PPNQLQFDFLGKDSIRYFNTVEVELPVYKAIGLFKSGKKDGEDLFDKLDTNKLNAHLKEL 883
            PPN LQFDFLGKDSIRY  TVEVELPVYKAI  F+ GK   +DLFDKLDT+KLNAHLKEL
Sbjct: 612  PPNSLQFDFLGKDSIRYEKTVEVELPVYKAIEQFRVGKSGSDDLFDKLDTSKLNAHLKEL 671

Query: 882  MPGLTAKVFRTYNASITLDGMLSNETKAGDVAEKIVIYQHANKEVAIICNHQRSVSKSHT 703
            MPGLTAKVFRTYNASITLD ML+ +TK GDVA+K+V+YQHANKEVAIICNHQR++SKSHT
Sbjct: 672  MPGLTAKVFRTYNASITLDEMLNKDTKEGDVAQKVVVYQHANKEVAIICNHQRTISKSHT 731

Query: 702  AQMSRLSEKMDELKAVMDELKTDLTRAKKGKPPLKDADGKQKKNLAPEALERKIAQTNAK 523
            AQM+RL+EK+DE+K V++ LKTDL RAKKGKPPLKDADGK ++NL PEALERKIAQTNAK
Sbjct: 732  AQMTRLTEKIDEMKGVLNGLKTDLARAKKGKPPLKDADGK-RRNLTPEALERKIAQTNAK 790

Query: 522  IEKMERDMRTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAMD 343
            IEKMERD  TKEDLKTVALGTSKINYLDPRISVAWCKR EVPIEK+FNKSLLAKFAWAMD
Sbjct: 791  IEKMERDKDTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKVFNKSLLAKFAWAMD 850

Query: 342  VDPSFRF 322
            V P FRF
Sbjct: 851  VPPDFRF 857


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score = 1030 bits (2664), Expect = 0.0
 Identities = 559/936 (59%), Positives = 641/936 (68%), Gaps = 39/936 (4%)
 Frame = -3

Query: 3012 MAVDTCVKPKFFXXXXXXDEPIVFKRNKTISKQNQLNSEIKKPSSQND-GLSGRHPRDAV 2836
            MAV+ C            + P++FKR+   SKQNQ NSE KK S Q   G S  H  D  
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDVR 60

Query: 2835 SPNGQNTSSHKRKVVSSTKALTTKFTIGNLKESTSIADKSK-----HSSGKSAGVNDAGX 2671
              NG+++S+ K ++  S +    K  + + K S S A  S       +S  SA       
Sbjct: 61   PANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAK 120

Query: 2670 XXXXXXXXXXNVD-------------SEDSDDDKPLSYRLPIASTTLPKSNSPRVSKGLX 2530
                       ++             SE SDD+KPL  R    S+   KSN      G  
Sbjct: 121  QQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSK-GKSNHANKEGGDS 179

Query: 2529 XXXXXXXXSEKAKVNXXXXXXXXXXXXXXXSRFKLKSC-GPSSVKKYDSDEEKPLASKIL 2353
                     E                     RF  KS  G S+ K YDSDE+KPLA+K+ 
Sbjct: 180  CSIRRPVVEESEDSEDEKPLSR---------RFPSKSSLGESTSKSYDSDEKKPLAAKVQ 230

Query: 2352 QNGSNKRDSELVKSHKVLNKRPLSDVSTSVQSAVKKPKLSDAXXXXXXXXXXXKAESKTD 2173
            QNGS  RD  + KS  + NKR   +V +  QS++KKPKLS             K E K +
Sbjct: 231  QNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAE 290

Query: 2172 DDDDYVPIGQRMKKLTVPDNKSQ------------------SAXXXXXXXXXXXXXXXXX 2047
            DDDD +P+ QR KK     +K +                  S                  
Sbjct: 291  DDDDNIPLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPS 350

Query: 2046 XXXXXXXXXXXXXXXXXXXSTKVPPGSGEGQKWTTLVHSGVIFPPPYKPHGVKMLYNGQP 1867
                               S+KVPPGSGEGQKWTTLVH+GV+FPPPYKPHGVKMLY  QP
Sbjct: 351  LKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQP 410

Query: 1866 VQLTPEQEEVATMFAVMKDTDYATKPKFIENFMTDWRPILGKNHVIKKFELCDFTPIYEW 1687
            + LTPEQEEVATMFA M DTDY  KP+F ENF +DW+ ILGKNH I+  E CDF PIYEW
Sbjct: 411  LTLTPEQEEVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEW 470

Query: 1686 HQREKEKKKQMSTDEKKAVKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 1507
            HQ+E+EKKKQM+T+EKKA+K+E+L+ EEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP
Sbjct: 471  HQQEREKKKQMTTEEKKALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHP 530

Query: 1506 KMGKLKRRIRPRDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKY 1327
            K+GKLK+RI PRDITINIGKDAPIPECPIPGERWKEV++DNTVTWLA+WNDP+N KE KY
Sbjct: 531  KVGKLKKRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKY 590

Query: 1326 VFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFVS-KDISKRQIAVATYLIDKL 1150
            VFLA SS+LKGQSDKEKYEKARLLKDYIH IRA YTKDF + KD  K+QIAVATYLIDKL
Sbjct: 591  VFLAPSSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKL 650

Query: 1149 ALRAGNEKDDDEADTVGCCTLKVENVSLVPPNQLQFDFLGKDSIRYFNTVEVELPVYKAI 970
            ALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+ DF+GKDSIRY N V+VE  V+KAI
Sbjct: 651  ALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAI 710

Query: 969  GLFKSGKKDGEDLFDKLDTNKLNAHLKELMPGLTAKVFRTYNASITLDGMLSNETKAGDV 790
              F+SGK+  EDLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD MLS ETK G V
Sbjct: 711  QQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKV 770

Query: 789  AEKIVIYQHANKEVAIICNHQRSVSKSHTAQMSRLSEKMDELKAVMDELKTDLTRAKKGK 610
            AEK+ +YQHANKEVAIICNHQR+VSKSH+AQMSRL+EK+DELK  ++ELKTDL+RAKKGK
Sbjct: 771  AEKVGVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGK 830

Query: 609  PPLKDADGKQKKNLAPEALERKIAQTNAKIEKMERDMRTKEDLKTVALGTSKINYLDPRI 430
            PP K  DG+ K+NL PEALERKIAQTNAKIEKMERD +TKEDLK VAL TSKI+YLDPRI
Sbjct: 831  PPSKGDDGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRI 890

Query: 429  SVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 322
            +VAWCKR EVPIEK+FNKSLLAKFAWAMDVDPSFRF
Sbjct: 891  TVAWCKRQEVPIEKMFNKSLLAKFAWAMDVDPSFRF 926