BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Akebia24_contig00005982
         (2528 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

emb|CBI28783.3| unnamed protein product [Vitis vinifera]             1001   0.0  
ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis v...   999   0.0  
ref|XP_002300344.1| DNA topoisomerase family protein [Populus tr...   984   0.0  
ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform ...   976   0.0  
ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinife...   975   0.0  
ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citr...   974   0.0  
ref|XP_002529020.1| DNA topoisomerase type I, putative [Ricinus ...   965   0.0  
ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobro...   950   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]               936   0.0  
ref|XP_002317355.1| DNA topoisomerase family protein [Populus tr...   936   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                 929   0.0  
ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis...   924   0.0  
ref|NP_001157806.1| topoisomerase I [Zea mays] gi|240065169|gb|A...   923   0.0  
gb|EMS46223.1| DNA topoisomerase 1 [Triticum urartu]                  920   0.0  
ref|XP_006659124.1| PREDICTED: DNA topoisomerase 1-like [Oryza b...   916   0.0  
ref|XP_007201211.1| hypothetical protein PRUPE_ppa001622mg [Prun...   914   0.0  
ref|XP_004972822.1| PREDICTED: DNA topoisomerase 1-like isoform ...   913   0.0  
ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...   912   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]       911   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]                911   0.0  

>emb|CBI28783.3| unnamed protein product [Vitis vinifera]
          Length = 724

 Score = 1001 bits (2589), Expect = 0.0
 Identities = 519/737 (70%), Positives = 570/737 (77%), Gaps = 17/737 (2%)
 Frame = -3

Query: 2523 SEDSEDEIPFSLRFKFKSGAGSSS-----------------EKFYDSNEEKPFASKIQQN 2395
            SEDSED+ P S +   +   G+S                  +   DS +E P   K+Q  
Sbjct: 16   SEDSEDDKPLSAKLSARLPKGNSHVLKGLSSPVLQSQKTKVDSSDDSEDEIPLLLKLQLK 75

Query: 2394 GSIKGGNELVKSPKVLNKRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDD 2215
             S KG +    S K+L+ + LS  +P++  P + QK            A V  +   +D 
Sbjct: 76   -SRKGAS----SSKLLDSKGLS--SPASSRP-QSQK------------AKVNNKNLSDDS 115

Query: 2214 DDDVPLSQRMXXXXXXXXXXXXXXXXKVFFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2035
            +D++PLS +                  +                                
Sbjct: 116  EDEIPLSSKFRLKTVSSDNKKASKTKVI--------PSSRKKATKKAKKSKKLAKSSKYS 167

Query: 2034 XXXXVPPSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMK 1855
                VPP+ GEG+KW+TLEHNGVIFPPPYK HGVKMLYNG+PVDLTPEQEEVATMFAVMK
Sbjct: 168  KSTKVPPNSGEGQKWTTLEHNGVIFPPPYKPHGVKMLYNGRPVDLTPEQEEVATMFAVMK 227

Query: 1854 DTEYATKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXX 1675
            DT+YATKPRFIENFMNDWR+ LGKNH+IKKFELC+FTPIYEWH  EKEKKKQM+T     
Sbjct: 228  DTDYATKPRFIENFMNDWRVRLGKNHVIKKFELCDFTPIYEWHEKEKEKKKQMTTEEKKA 287

Query: 1674 XXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINI 1495
                      KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI PSDITINI
Sbjct: 288  LKEEKLKQEDKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINI 347

Query: 1494 GKDAPIPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKY 1315
            GK+AP+PECPIPG+RWKEV+HDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKY
Sbjct: 348  GKEAPVPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKY 407

Query: 1314 EKARVLKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCC 1135
            EKAR+LKDYI +IRATYTKDF +KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCC
Sbjct: 408  EKARLLKDYIQNIRATYTKDFTNKDTMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCC 467

Query: 1134 TLKVENVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDT 955
            TLKVENV LVPPNKL+FDFLGKDS+RYFNTVEVELPVYKAIGQFK+GKS GDDLFDKLDT
Sbjct: 468  TLKVENVALVPPNKLEFDFLGKDSIRYFNTVEVELPVYKAIGQFKTGKSGGDDLFDKLDT 527

Query: 954  SKLNAHLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICN 775
            SKLNAHLKELMPGLTAKVFRTYNASITLDEMLNRE + G+  EKIVIYQHANKEVAIICN
Sbjct: 528  SKLNAHLKELMPGLTAKVFRTYNASITLDEMLNREARGGDAMEKIVIYQHANKEVAIICN 587

Query: 774  HQRSVSKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEAL 595
            HQRSVSKSH  QMSRLSEKM EL+ VLDELKTDL RAKKGKPPL D+DGKPKKN+TPE L
Sbjct: 588  HQRSVSKSHDVQMSRLSEKMRELQGVLDELKTDLARAKKGKPPLKDSDGKPKKNMTPEVL 647

Query: 594  EKKIAQTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKS 415
            E+KIAQTN KIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKR EVPIEKIFNKS
Sbjct: 648  ERKIAQTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKS 707

Query: 414  LLAKFAWSMDVDPTFRF 364
            LLAKFAW+MDVDP+FRF
Sbjct: 708  LLAKFAWAMDVDPSFRF 724


>ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis vinifera]
          Length = 883

 Score =  999 bits (2583), Expect = 0.0
 Identities = 483/552 (87%), Positives = 512/552 (92%)
 Frame = -3

Query: 2019 PPSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYA 1840
            PP+ GEG+KW+TLEHNGVIFPPPYK HGVKMLYNG+PVDLTPEQEEVATMFAVMKDT+YA
Sbjct: 332  PPNSGEGQKWTTLEHNGVIFPPPYKPHGVKMLYNGRPVDLTPEQEEVATMFAVMKDTDYA 391

Query: 1839 TKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXX 1660
            TKPRFIENFMNDWR+ LGKNH+IKKFELC+FTPIYEWH  EKEKKKQM+T          
Sbjct: 392  TKPRFIENFMNDWRVRLGKNHVIKKFELCDFTPIYEWHEKEKEKKKQMTTEEKKALKEEK 451

Query: 1659 XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1480
                 KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI PSDITINIGK+AP
Sbjct: 452  LKQEDKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGKEAP 511

Query: 1479 IPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARV 1300
            +PECPIPG+RWKEV+HDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR+
Sbjct: 512  VPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARL 571

Query: 1299 LKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 1120
            LKDYI +IRATYTKDF +KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE
Sbjct: 572  LKDYIQNIRATYTKDFTNKDTMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 631

Query: 1119 NVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNA 940
            NV LVPPNKL+FDFLGKDS+RYFNTVEVELPVYKAIGQFK+GKS GDDLFDKLDTSKLNA
Sbjct: 632  NVALVPPNKLEFDFLGKDSIRYFNTVEVELPVYKAIGQFKTGKSGGDDLFDKLDTSKLNA 691

Query: 939  HLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSV 760
            HLKELMPGLTAKVFRTYNASITLDEMLNRE + G+  EKIVIYQHANKEVAIICNHQRSV
Sbjct: 692  HLKELMPGLTAKVFRTYNASITLDEMLNREARGGDAMEKIVIYQHANKEVAIICNHQRSV 751

Query: 759  SKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIA 580
            SKSH  QMSRLSEKM EL+ VLDELKTDL RAKKGKPPL D+DGKPKKN+TPE LE+KIA
Sbjct: 752  SKSHDVQMSRLSEKMRELQGVLDELKTDLARAKKGKPPLKDSDGKPKKNMTPEVLERKIA 811

Query: 579  QTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKF 400
            QTN KIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKR EVPIEKIFNKSLLAKF
Sbjct: 812  QTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKSLLAKF 871

Query: 399  AWSMDVDPTFRF 364
            AW+MDVDP+FRF
Sbjct: 872  AWAMDVDPSFRF 883



 Score =  100 bits (250), Expect = 3e-18
 Identities = 54/106 (50%), Positives = 69/106 (65%)
 Frame = -3

Query: 2523 SEDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLN 2344
            S+DSEDEIP S +F+ K+G G+S +K  + +E+KP  S ++ NG  K  +E VKSPK  N
Sbjct: 167  SDDSEDEIPLSSKFRLKTGMGASLDKLDNFDEKKPLTSTLKPNGISKKDDERVKSPKGQN 226

Query: 2343 KRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDD 2206
            KR L  AN S     KK KL D  V GK+ Q  VKAEQK +DDDD+
Sbjct: 227  KRPLGQANTSHHSSSKKPKLLDGSVKGKVKQVSVKAEQKDDDDDDN 272


>ref|XP_002300344.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222847602|gb|EEE85149.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 877

 Score =  984 bits (2545), Expect = 0.0
 Identities = 506/716 (70%), Positives = 552/716 (77%)
 Frame = -3

Query: 2511 EDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLNKRTL 2332
            +DE+P S RF  KS AG+SS K   S+E +PF SK Q NGS K   +  KS  V  KR +
Sbjct: 171  DDEVPLSSRFAMKSNAGTSSSKSIRSSEIRPFPSKSQLNGSTKNDKQQ-KSSVVPTKRPM 229

Query: 2331 SDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQRMXXXXXXXXXXX 2152
             +  PS     KK KL D     K+ Q  VK EQK  DDDD + +SQRM           
Sbjct: 230  DNKVPSNHSSAKKPKLLDACTTTKVKQVTVKVEQKA-DDDDHLTISQRMKKADSSANKSS 288

Query: 2151 XXXXXKVFFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPSFGEGKKWSTLEHN 1972
                   F                                    P S    KKW+TL HN
Sbjct: 289  -------FAKKKVTKVVSSSLKKTTQKNKKQMKNSKYSKSTKVQPGSSDGQKKWTTLVHN 341

Query: 1971 GVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYATKPRFIENFMNDWRLI 1792
            GVIFPPPYK HGVK+LY G+P+DLTPEQEEVATMFAVMKDT+Y  KP+F +NF NDWR +
Sbjct: 342  GVIFPPPYKPHGVKILYKGKPIDLTPEQEEVATMFAVMKDTDYVQKPQFRQNFWNDWRKL 401

Query: 1791 LGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVK 1612
            LGKNH+I+K + C+F PIYEWH  EKEKKKQMST               KYMWAIV+GVK
Sbjct: 402  LGKNHVIQKLDDCDFNPIYEWHQQEKEKKKQMSTEEKKVLKEEKLKQEEKYMWAIVNGVK 461

Query: 1611 EKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGQRWKEVKH 1432
            EKVGNFRVEPPGLFRGRGEHPKMGKLK RIRPSDITINIGKDAPIPECPIPG+RWKEVKH
Sbjct: 462  EKVGNFRVEPPGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPECPIPGERWKEVKH 521

Query: 1431 DNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARVLKDYIHDIRATYTKDF 1252
            DNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIH+IRA YTKDF
Sbjct: 522  DNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIRAAYTKDF 581

Query: 1251 ASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPNKLQFDFLG 1072
            ASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NVE +PPNKL+FDFLG
Sbjct: 582  ASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLG 641

Query: 1071 KDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNAHLKELMPGLTAKVFRT 892
            KDS+RY NTVEVELPVYKAIG F+  K + DDLFD LDTSKLNAHLKELMPGLTAKVFRT
Sbjct: 642  KDSIRYENTVEVELPVYKAIGHFQVAKKQTDDLFDSLDTSKLNAHLKELMPGLTAKVFRT 701

Query: 891  YNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSVSKSHSAQMSRLSEKMD 712
            YNASITLDE L  ET+DG+VAEKIVIY  ANK+VAIICNHQR++SKSH AQMSRL+EK++
Sbjct: 702  YNASITLDEKLYEETEDGDVAEKIVIYNQANKQVAIICNHQRTISKSHDAQMSRLTEKIE 761

Query: 711  ELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIAQTNVKIEKMERDMKTK 532
            ELK+ L ELKTDL RAKKGKPPL  ADGK K++LTPEA+EKKIA TN KIEKME  MKTK
Sbjct: 762  ELKSTLKELKTDLDRAKKGKPPLKGADGKQKRSLTPEAIEKKIATTNQKIEKMEMAMKTK 821

Query: 531  EDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPTFRF 364
            EDLKTVALGTSKINYLDPRI+VAWCKRHEVPI+KIFNKSLLAKF W+MDVDP FRF
Sbjct: 822  EDLKTVALGTSKINYLDPRITVAWCKRHEVPIDKIFNKSLLAKFTWAMDVDPQFRF 877


>ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform X1 [Citrus sinensis]
            gi|568842074|ref|XP_006474978.1| PREDICTED: DNA
            topoisomerase 1-like isoform X2 [Citrus sinensis]
            gi|568842076|ref|XP_006474979.1| PREDICTED: DNA
            topoisomerase 1-like isoform X3 [Citrus sinensis]
            gi|568842078|ref|XP_006474980.1| PREDICTED: DNA
            topoisomerase 1-like isoform X4 [Citrus sinensis]
          Length = 902

 Score =  976 bits (2522), Expect = 0.0
 Identities = 503/720 (69%), Positives = 559/720 (77%), Gaps = 1/720 (0%)
 Frame = -3

Query: 2520 EDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLNK 2341
            EDS+DE+P S RF  KS AG+S  K  DS+E+KP ASK+QQNGS     +  KS  V  K
Sbjct: 193  EDSDDEVPLSSRFP-KSNAGTSGAKPIDSDEKKPLASKVQQNGSTSRETQ-QKSSSVPVK 250

Query: 2340 RTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQRMXXXXXXXX 2161
            R L  A+ S     KK K+SD     K+ Q  VK E+K  DDDD +P+SQRM        
Sbjct: 251  RPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKK-ADDDDHIPISQRM-------K 302

Query: 2160 XXXXXXXXKVFFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPSFGEGKKWSTL 1981
                     V                                    +P S    KKW+TL
Sbjct: 303  NSAPSVKKSVTNTAKATKSVSSSSNKINKKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTL 362

Query: 1980 EHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYATKPRFIENFMNDW 1801
             HNGVIFPPPY  HGVKMLY G+ V+LTPEQEEVATMFAVM DT+Y  KP+F ENF NDW
Sbjct: 363  VHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDW 422

Query: 1800 RLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVD 1621
            R +LGKNH+I+  E C+F PIY+WH  +KEKKKQMS+               KYMWAIVD
Sbjct: 423  RKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEKLKQEEKYMWAIVD 482

Query: 1620 GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGQRWKE 1441
            GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI+PSDITINIGKD PIPECPIPG+ WKE
Sbjct: 483  GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVPIPECPIPGESWKE 542

Query: 1440 VKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARVLKDYIHDIRATYT 1261
            VKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIH IRA YT
Sbjct: 543  VKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHSIRAAYT 602

Query: 1260 KDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPNKLQFD 1081
            KDF S+D T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NVE +PPNKL+FD
Sbjct: 603  KDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLKFD 662

Query: 1080 FLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNAHLKELMPGLTAKV 901
            FLGKDS++Y NTVEVELPVYKAIGQF++GK + DDLFDKLDT+KLNAHLKELMPGLTAKV
Sbjct: 663  FLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKV 722

Query: 900  FRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSVSKSHSAQMSRLSE 721
            FRTYNASITLD MLN+ T DG+VA KI +YQ ANKEVAIICNHQR+VSK+HSAQMSRL+E
Sbjct: 723  FRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTE 782

Query: 720  KMDELKAVLDELKTDLVRAKKGKPPL-NDADGKPKKNLTPEALEKKIAQTNVKIEKMERD 544
            K+++LK VL +L+ DL RAKKGKPPL  D+DGK K+NL PEALE+K+AQTN KIEKMERD
Sbjct: 783  KIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERD 842

Query: 543  MKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPTFRF 364
            MKTKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 843  MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPEFRF 902


>ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinifera]
            gi|296082698|emb|CBI21703.3| unnamed protein product
            [Vitis vinifera]
          Length = 857

 Score =  975 bits (2521), Expect = 0.0
 Identities = 510/724 (70%), Positives = 562/724 (77%), Gaps = 5/724 (0%)
 Frame = -3

Query: 2520 EDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLNK 2341
            +D +D+IP S +F+ KS            +E+KP   K+ QNG   G ++  KSP VLNK
Sbjct: 155  DDDDDKIPLSSKFQLKS------------DEKKPLPLKVNQNG---GTDKRDKSPTVLNK 199

Query: 2340 -RTLSDANPSA--QCPIKKQKLSDIPVHG-KIGQAHVKAEQKIEDDDDD-VPLSQRMXXX 2176
             R L   N S      +KK K+S       K+  A  KAE K+EDDDDD +P+SQRM   
Sbjct: 200  KRPLDGVNSSLGQSSLVKKPKISGQSAQPFKVTHATAKAEPKVEDDDDDDMPISQRMKKS 259

Query: 2175 XXXXXXXXXXXXXKVFFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPSFGEGK 1996
                         KV                                    VPPS GEG+
Sbjct: 260  GASSGNKPVPAKQKV-----TKVVSSTSFKKTKDIKSKKMEKNSKYSKSTKVPPSSGEGQ 314

Query: 1995 KWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYATKPRFIEN 1816
            KW+TL HNGVIFPPPYK HGVKMLY G+PVDLTPEQEEVATMFAVM DT+Y  K +F EN
Sbjct: 315  KWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMQKEKFKEN 374

Query: 1815 FMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXXXXXXXKYM 1636
            FM DWR ILGKNH+I++ + C+FTPIYEWH  EKEKKKQMST               KYM
Sbjct: 375  FMADWRKILGKNHVIQRLDDCDFTPIYEWHQEEKEKKKQMSTEEKKTLKEEKLKLEEKYM 434

Query: 1635 WAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPG 1456
            WAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRI PSDITINIGK++ IPECPIPG
Sbjct: 435  WAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIHPSDITINIGKNSQIPECPIPG 494

Query: 1455 QRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARVLKDYIHDI 1276
            + WKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LK+YI DI
Sbjct: 495  ESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKNYIKDI 554

Query: 1275 RATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPN 1096
            RATYTKDF SKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV   PPN
Sbjct: 555  RATYTKDFVSKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVIPEPPN 614

Query: 1095 KLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNAHLKELMPG 916
             LQFDFLGKDS+RY  TVEVELPVYKAI QF+ GKS  DDLFDKLDTSKLNAHLKELMPG
Sbjct: 615  SLQFDFLGKDSIRYEKTVEVELPVYKAIEQFRVGKSGSDDLFDKLDTSKLNAHLKELMPG 674

Query: 915  LTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSVSKSHSAQM 736
            LTAKVFRTYNASITLDEMLN++TK+G+VA+K+V+YQHANKEVAIICNHQR++SKSH+AQM
Sbjct: 675  LTAKVFRTYNASITLDEMLNKDTKEGDVAQKVVVYQHANKEVAIICNHQRTISKSHTAQM 734

Query: 735  SRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIAQTNVKIEK 556
            +RL+EK+DE+K VL+ LKTDL RAKKGKPPL DADGK ++NLTPEALE+KIAQTN KIEK
Sbjct: 735  TRLTEKIDEMKGVLNGLKTDLARAKKGKPPLKDADGK-RRNLTPEALERKIAQTNAKIEK 793

Query: 555  MERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDP 376
            MERD  TKEDLKTVALGTSKINYLDPRISVAWCKR EVPIEK+FNKSLLAKFAW+MDV P
Sbjct: 794  MERDKDTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKVFNKSLLAKFAWAMDVPP 853

Query: 375  TFRF 364
             FRF
Sbjct: 854  DFRF 857


>ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|567920950|ref|XP_006452481.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555705|gb|ESR65719.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555707|gb|ESR65721.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 902

 Score =  974 bits (2519), Expect = 0.0
 Identities = 502/720 (69%), Positives = 559/720 (77%), Gaps = 1/720 (0%)
 Frame = -3

Query: 2520 EDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLNK 2341
            EDS+DE+P S RF  KS AG+S  K  DS+E+KP ASK+QQNGS     +  KS  V  K
Sbjct: 193  EDSDDEVPLSSRFP-KSNAGTSGAKPIDSDEKKPLASKVQQNGSTSRETQ-QKSSSVPVK 250

Query: 2340 RTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQRMXXXXXXXX 2161
            R L  A+ S     KK K+SD     K+ Q  VK E+K  DDDD +P+SQRM        
Sbjct: 251  RPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKK-ADDDDHIPISQRM-------K 302

Query: 2160 XXXXXXXXKVFFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPSFGEGKKWSTL 1981
                     V                                    +P S    KKW+TL
Sbjct: 303  NSAPSVKKSVTNTAKATKSVSSSSKKINKKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTL 362

Query: 1980 EHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYATKPRFIENFMNDW 1801
             HNGVIFPPPY  HGVKMLY G+ V+LTPEQEEVATMFAVM DT+Y  KP+F ENF NDW
Sbjct: 363  VHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDW 422

Query: 1800 RLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIVD 1621
            R +LGKNH+I+  E C+F PIY+WH  +KEKKKQMS+               KYMWAIVD
Sbjct: 423  RKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEKLKQEEKYMWAIVD 482

Query: 1620 GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGQRWKE 1441
            GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI+PSDITINIGKD PIPECPIPG+ WKE
Sbjct: 483  GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVPIPECPIPGESWKE 542

Query: 1440 VKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARVLKDYIHDIRATYT 1261
            VKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSD+EKYEKAR LKDYIH IRA YT
Sbjct: 543  VKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDREKYEKARKLKDYIHSIRAAYT 602

Query: 1260 KDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPNKLQFD 1081
            KDF S+D T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NVE +PPNKL+FD
Sbjct: 603  KDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLKFD 662

Query: 1080 FLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNAHLKELMPGLTAKV 901
            FLGKDS++Y NTVEVELPVYKAIGQF++GK + DDLFDKLDT+KLNAHLKELMPGLTAKV
Sbjct: 663  FLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKV 722

Query: 900  FRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSVSKSHSAQMSRLSE 721
            FRTYNASITLD MLN+ T DG+VA KI +YQ ANKEVAIICNHQR+VSK+HSAQMSRL+E
Sbjct: 723  FRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTE 782

Query: 720  KMDELKAVLDELKTDLVRAKKGKPPL-NDADGKPKKNLTPEALEKKIAQTNVKIEKMERD 544
            K+++LK VL +L+ DL RAKKGKPPL  D+DGK K+NL PEALE+K+AQTN KIEKMERD
Sbjct: 783  KIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERD 842

Query: 543  MKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPTFRF 364
            MKTKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAKFAW+MDVDP FRF
Sbjct: 843  MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPEFRF 902


>ref|XP_002529020.1| DNA topoisomerase type I, putative [Ricinus communis]
            gi|223531500|gb|EEF33331.1| DNA topoisomerase type I,
            putative [Ricinus communis]
          Length = 891

 Score =  965 bits (2495), Expect = 0.0
 Identities = 497/721 (68%), Positives = 554/721 (76%), Gaps = 2/721 (0%)
 Frame = -3

Query: 2520 EDSEDE-IPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLN 2344
            EDS+D+ +P   RF  KS AG+S  K  + +E+KP  SK+QQNGS     +  K+P +  
Sbjct: 182  EDSDDDKVPLCSRFPMKSTAGTSGNKPNNISEKKPLPSKVQQNGSTSKDKQQ-KAPLIPT 240

Query: 2343 KRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQRMXXXXXXX 2164
            KR L  AN S Q  IKK KLS      K+ QA VKAE   EDD DD+P++QR        
Sbjct: 241  KRPLDKANSSEQSSIKKPKLSAGSTITKVKQATVKAE---EDDPDDIPIAQRKKSLGSSE 297

Query: 2163 XXXXXXXXXKVFFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPSFGEGKKWST 1984
                      +                                     P S    KKW+T
Sbjct: 298  SKLSSAKQKAI-------KVVSSSFKKPIKKNKKQMKNTKYSKSTKVQPSSTDGQKKWTT 350

Query: 1983 LEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYATKPRFIENFMND 1804
            L HNGVIFPPPYK HG+K+LY G+PVDL PEQEEVATMFAVMKDT+Y  KP+F+ENF ND
Sbjct: 351  LIHNGVIFPPPYKPHGIKILYKGRPVDLAPEQEEVATMFAVMKDTDYMQKPKFLENFWND 410

Query: 1803 WRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAIV 1624
            WR +LG+NH+I+K E C+FTPIYEWH  EKEKKKQMST               KYMWAIV
Sbjct: 411  WRKLLGRNHVIQKLEDCDFTPIYEWHEREKEKKKQMSTEEKKAQKEEKLRQEEKYMWAIV 470

Query: 1623 DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGQRWK 1444
            DGVKEKVGNFRVEPP LFRGRGEHPKMGKLK+RI+PSDITINIGKDAPIPECPIPG+ WK
Sbjct: 471  DGVKEKVGNFRVEPPALFRGRGEHPKMGKLKKRIQPSDITINIGKDAPIPECPIPGESWK 530

Query: 1443 EVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARVLKDYIHDIRATY 1264
            EVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIH+IRA Y
Sbjct: 531  EVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIRAAY 590

Query: 1263 TKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPN-KLQ 1087
             KD  SKDITK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NVE +P +  L+
Sbjct: 591  QKDLRSKDITKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPGSFNLK 650

Query: 1086 FDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNAHLKELMPGLTA 907
            FDFLGKDS+RY NTVEV+  VY+AIG F+ GK + DDLFDKLDT+KLNAHLKELMPGLTA
Sbjct: 651  FDFLGKDSIRYENTVEVKPEVYEAIGTFQKGKKQTDDLFDKLDTTKLNAHLKELMPGLTA 710

Query: 906  KVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSVSKSHSAQMSRL 727
            KVFRTYNASITLDE L  ET+DG+VAEK+VIYQ ANKEVAIICNHQR++SKSH AQMS+L
Sbjct: 711  KVFRTYNASITLDEKLYEETEDGDVAEKVVIYQRANKEVAIICNHQRTISKSHGAQMSKL 770

Query: 726  SEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIAQTNVKIEKMER 547
             EK++ELKA L ELKTDL RAKKGKPPL DADGK K+NL+PE +EKKIA TN +IEKME 
Sbjct: 771  IEKIEELKATLKELKTDLDRAKKGKPPLKDADGKQKRNLSPENIEKKIASTNQRIEKMEL 830

Query: 546  DMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPTFR 367
            +MKTKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAKF W+MDVDP FR
Sbjct: 831  NMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPQFR 890

Query: 366  F 364
            F
Sbjct: 891  F 891


>ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
            gi|590606147|ref|XP_007020665.1| DNA topoisomerase I
            alpha isoform 1 [Theobroma cacao]
            gi|508720292|gb|EOY12189.1| DNA topoisomerase I alpha
            isoform 1 [Theobroma cacao] gi|508720293|gb|EOY12190.1|
            DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
          Length = 904

 Score =  950 bits (2455), Expect = 0.0
 Identities = 461/553 (83%), Positives = 501/553 (90%), Gaps = 1/553 (0%)
 Frame = -3

Query: 2019 PPSFGEG-KKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEY 1843
            PPS G+G KKWSTL HNGVIFP PY  HGVKMLY+G+PVDLTPEQEEVATMFAVMKDT+Y
Sbjct: 352  PPSSGDGQKKWSTLVHNGVIFPSPYTPHGVKMLYDGRPVDLTPEQEEVATMFAVMKDTDY 411

Query: 1842 ATKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXX 1663
             +K +F +NF  DW  +LGKNH IK  + C+FTPIYEWHL EKEKKKQMS+         
Sbjct: 412  MSKTQFKKNFWEDWSKLLGKNHTIKDLDRCDFTPIYEWHLQEKEKKKQMSSEEKKALKEE 471

Query: 1662 XXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDA 1483
                  K+MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDA
Sbjct: 472  KLKQEEKFMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDA 531

Query: 1482 PIPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 1303
            PIPECPIPG+RWK++KHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR
Sbjct: 532  PIPECPIPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 591

Query: 1302 VLKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 1123
            +LKDYI +IRA YTKDF +KD+ KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 592  MLKDYIKNIRAAYTKDFTTKDVMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 651

Query: 1122 ENVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLN 943
             NVE +PPNKL+FDFLGKDS++Y NTVEVELPVYKAIGQF++GKS+ DDLFDKLDTSKLN
Sbjct: 652  GNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKSKSDDLFDKLDTSKLN 711

Query: 942  AHLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRS 763
            AHLKELMPGLTAKVFRTYNASITLDEMLN+ETKDG+VAEK+V+YQ ANKEVAIICNHQRS
Sbjct: 712  AHLKELMPGLTAKVFRTYNASITLDEMLNKETKDGDVAEKVVVYQRANKEVAIICNHQRS 771

Query: 762  VSKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKI 583
            +SKSHSAQMSRL+EK+ ELK VL ELK DL RAKKGKPPL DADGK K+NLTP+A++KKI
Sbjct: 772  ISKSHSAQMSRLTEKITELKGVLKELKIDLDRAKKGKPPLKDADGKQKRNLTPQAIQKKI 831

Query: 582  AQTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAK 403
             QTN KIEKMERDM+TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAK
Sbjct: 832  DQTNAKIEKMERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAK 891

Query: 402  FAWSMDVDPTFRF 364
            FAW+MDVDP FRF
Sbjct: 892  FAWAMDVDPDFRF 904



 Score = 97.1 bits (240), Expect = 4e-17
 Identities = 55/114 (48%), Positives = 69/114 (60%)
 Frame = -3

Query: 2526 SSEDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVL 2347
            S+ED +DE P S RF  KS  G+SS + +D +E+KP ASKIQQNGSI  G +   S  + 
Sbjct: 193  SAEDPDDEAPLSARFNVKSNTGTSSSRLHDCDEKKPLASKIQQNGSIMKGKQ-QNSSTLS 251

Query: 2346 NKRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQRM 2185
             KR L   N S     KK K SD P   K  Q  VKAE K ++DDD +P++QRM
Sbjct: 252  GKRPLDKGNSSDHSSAKKPKTSDAPTTMKTKQVTVKAE-KADEDDDHMPIAQRM 304


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score =  936 bits (2420), Expect = 0.0
 Identities = 455/552 (82%), Positives = 494/552 (89%)
 Frame = -3

Query: 2019 PPSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYA 1840
            PPS GEGKKW+TL HNGVIFPPPYK HGVKMLY G+PVDLTPEQEEVATMFAVM DT+Y 
Sbjct: 343  PPSSGEGKKWNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYM 402

Query: 1839 TKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXX 1660
            TK +F ENFM+DWR ILGKNH+I+  E C+FTPIYEWH  EKEKKK+M+           
Sbjct: 403  TKSKFKENFMDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEER 462

Query: 1659 XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1480
                 KYMWAIV+GVKEKVGNFRVEPP LFRGRGEHPKMGKLK+ IRPSDITINIGKDAP
Sbjct: 463  LKQEEKYMWAIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAP 522

Query: 1479 IPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARV 1300
            IPECPIPG+ WKE++HDNTVTWLAFWNDPI P+EFKYVFLAASSSLKGQSDKEKYEKAR+
Sbjct: 523  IPECPIPGESWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARL 582

Query: 1299 LKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 1120
            LKD+I  IRA YTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE
Sbjct: 583  LKDFIQGIRAAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 642

Query: 1119 NVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNA 940
            NVE  PP+ L+FDFLGKDS+RY N VEVELPVYKAI QF++GK  GDDLFDKLDTSKLNA
Sbjct: 643  NVEPKPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNA 702

Query: 939  HLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSV 760
            HLK LMPGLTAKVFRTYNASITLDEML+RETK G VAEKIV+YQHANKEVAIICNHQR+V
Sbjct: 703  HLKGLMPGLTAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTV 762

Query: 759  SKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIA 580
            SKSH AQM+RL+ K+DELK +LD L+TDL RAKKGKPPL DADGKPK+NLTPEALE+KI 
Sbjct: 763  SKSHPAQMTRLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKIG 822

Query: 579  QTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKF 400
            QTN KIEKMERD +TKE LKT+ALGTSKI+YLDPRI+VAWCKRHEVPIEK+FNKSLLAKF
Sbjct: 823  QTNAKIEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSLLAKF 882

Query: 399  AWSMDVDPTFRF 364
            AWSMDVDP+FRF
Sbjct: 883  AWSMDVDPSFRF 894



 Score = 97.4 bits (241), Expect = 3e-17
 Identities = 58/116 (50%), Positives = 75/116 (64%), Gaps = 3/116 (2%)
 Frame = -3

Query: 2523 SEDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLN 2344
            S+DS+DEIP S +F+ K+ AG+S+ K Y+S++ K   S  QQNGSI  G+   KS   +N
Sbjct: 185  SDDSDDEIPLSSKFRLKANAGTSTVKSYESDDNKTLVSNFQQNGSINRGS---KSSIKVN 241

Query: 2343 KRTLSDANPSAQCPIKKQKLSD--IPVHGKIGQAHVKAEQKIEDDDDD-VPLSQRM 2185
            KR L +   S Q  +KK KLSD   PV+ K  QA  KAE K +D DDD VP+SQRM
Sbjct: 242  KRPLGEVKSSVQSSVKKPKLSDASTPVNNK--QASKKAEPKADDSDDDHVPISQRM 295


>ref|XP_002317355.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222860420|gb|EEE97967.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 860

 Score =  936 bits (2418), Expect = 0.0
 Identities = 456/552 (82%), Positives = 484/552 (87%)
 Frame = -3

Query: 2019 PPSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYA 1840
            P S    KKW TL HNGVIFPPPYK HGVKMLY G+PVDLTPEQEEVATMFAVMKDTEY 
Sbjct: 309  PGSSDGQKKWKTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTEYV 368

Query: 1839 TKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXX 1660
             KP+F++NF NDWR +LGKNH+I+K E C+F PIYEWH  EKEKKKQMST          
Sbjct: 369  QKPQFLQNFWNDWRTLLGKNHVIQKLEACDFNPIYEWHQKEKEKKKQMSTEEKKAVREEK 428

Query: 1659 XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1480
                  YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK RIRPSDITINIGKDAP
Sbjct: 429  LKQEEMYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAP 488

Query: 1479 IPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARV 1300
            IP+CPIPG+RWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 
Sbjct: 489  IPKCPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARK 548

Query: 1299 LKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 1120
            LKDYIH+IR  YTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 
Sbjct: 549  LKDYIHNIRTAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVA 608

Query: 1119 NVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNA 940
            NVE +PPNKL+FDFLGKDS+RY NTVEVELPVYKAI QF+  K   DDLFD LDTSKLNA
Sbjct: 609  NVECIPPNKLKFDFLGKDSIRYENTVEVELPVYKAIRQFQVAKKPTDDLFDSLDTSKLNA 668

Query: 939  HLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSV 760
            HLKELMPGLTAKVFRTYNASITLDE L  ET+DG+VAEK VIY  ANK+VAIICNHQR++
Sbjct: 669  HLKELMPGLTAKVFRTYNASITLDEKLYEETEDGDVAEKFVIYNQANKQVAIICNHQRTI 728

Query: 759  SKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIA 580
            SKSH AQMSRL+EK++ELK  L E KTDL RAKKGKPPL DADGK K+NLTPEA+EKKIA
Sbjct: 729  SKSHDAQMSRLTEKLEELKGTLKEFKTDLDRAKKGKPPLKDADGKQKRNLTPEAIEKKIA 788

Query: 579  QTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKF 400
             TN KIEKME  MKTKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAKF
Sbjct: 789  TTNQKIEKMELSMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 848

Query: 399  AWSMDVDPTFRF 364
             W+MDVDP FRF
Sbjct: 849  TWAMDVDPQFRF 860



 Score = 70.1 bits (170), Expect = 5e-09
 Identities = 51/109 (46%), Positives = 61/109 (55%)
 Frame = -3

Query: 2511 EDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLNKRTL 2332
            +DE+P S RF  KS AGSSS K   S+E+    SKIQ NGS    ++  KS  V  KR +
Sbjct: 157  DDEVPLSSRFAAKSNAGSSSCKTISSSEKILLVSKIQLNGS-TAKDKQQKSSAVPTKRPM 215

Query: 2331 SDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQRM 2185
             +  PS Q   KK KLSD        Q  VKAE K  DDDD + +SQRM
Sbjct: 216  DNKVPSNQSFAKKPKLSDA---STTKQVTVKAELK-ADDDDHLTISQRM 260


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score =  929 bits (2400), Expect = 0.0
 Identities = 452/554 (81%), Positives = 493/554 (88%), Gaps = 2/554 (0%)
 Frame = -3

Query: 2019 PPSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYA 1840
            PPS GEGKKW+ LEHNGVIFPPPYK HG+KMLY G+PVDLTPEQEEVATMFAVM DT+Y 
Sbjct: 357  PPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYM 416

Query: 1839 TKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXX 1660
             KPRF ENF  DW+ ILGKNH+I+  E C+F+PIYEWH +EKEKKKQM+T          
Sbjct: 417  NKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEEKKALKEEK 476

Query: 1659 XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1480
                 KYMWA VDG KEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP DITINIGKDAP
Sbjct: 477  LKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKDAP 536

Query: 1479 IPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARV 1300
            IPECP+PG+RWKEV+HDNTVTWLAFWNDPINPKEFKYVFLAASS+LKG SDKEKYEKAR+
Sbjct: 537  IPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYEKARL 596

Query: 1299 LKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 1120
            LKDYI  IRA YTKDFASKD TK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE
Sbjct: 597  LKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 656

Query: 1119 NVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNA 940
            NVE VPPN L+FDFLGKDS+RY N VEVE  V+KAI QF+SGK    DLFD LDTSKLNA
Sbjct: 657  NVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNA 716

Query: 939  HLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSV 760
            HLKELMPGLTAKVFRTYNASITLD+ML+RETK G+VAEK+V+YQHANKEVAIICNHQR+V
Sbjct: 717  HLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTV 776

Query: 759  SKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPL--NDADGKPKKNLTPEALEKK 586
            SKSHSAQM RL+EK++ELKAV++ELK+DL R KKGKPPL   +ADGKPK+NL PE+LEKK
Sbjct: 777  SKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKK 836

Query: 585  IAQTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLA 406
            IAQTN KIEKMERD +TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLA
Sbjct: 837  IAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLA 896

Query: 405  KFAWSMDVDPTFRF 364
            KF W+MDVDP+FRF
Sbjct: 897  KFTWAMDVDPSFRF 910



 Score = 98.2 bits (243), Expect = 2e-17
 Identities = 54/114 (47%), Positives = 68/114 (59%), Gaps = 1/114 (0%)
 Frame = -3

Query: 2523 SEDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLN 2344
            +EDS+DE P S RF  KSG G S+ K YDS+++KP A K+Q NGS     +  K   + N
Sbjct: 197  NEDSDDEKPLSSRFPLKSGVGESTSKAYDSDDDKPLAKKLQHNGSAMRDGQPNKYSNMSN 256

Query: 2343 KRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDD-VPLSQRM 2185
            KR   D   S Q  +KK KLS +       QA VK E K EDDDDD +P+SQR+
Sbjct: 257  KRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQASVKPEPKAEDDDDDHLPISQRI 310


>ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis sativus]
            gi|449503189|ref|XP_004161878.1| PREDICTED: DNA
            topoisomerase 1-like [Cucumis sativus]
          Length = 889

 Score =  924 bits (2387), Expect = 0.0
 Identities = 452/552 (81%), Positives = 495/552 (89%), Gaps = 1/552 (0%)
 Frame = -3

Query: 2016 PSFGEG-KKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYA 1840
            PS G+G KKW+TL HNGVIFPPPY++HGVKMLY G+PVDLTP QEEVATMFAVMKDT+Y 
Sbjct: 338  PSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPPQEEVATMFAVMKDTDYM 397

Query: 1839 TKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXX 1660
             KP+F ENF NDWR +LGKNH+I+  + C+FTPIY+W+  EKEKKKQM+T          
Sbjct: 398  LKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQMEKEKKKQMTTEEKKAVKEEK 457

Query: 1659 XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1480
                 KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRI PSDITINIGK AP
Sbjct: 458  LKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRICPSDITINIGKGAP 517

Query: 1479 IPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARV 1300
            IPECPIPG+RWKEV+HDNTVTWLAFWNDPIN KEFKYVFLAASSSLKGQSDKEKYEKAR+
Sbjct: 518  IPECPIPGERWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARM 577

Query: 1299 LKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 1120
            LKDYI +IR  YTKDF SKD T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE
Sbjct: 578  LKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 637

Query: 1119 NVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNA 940
            NV+ VPPN L+F+FLGKDS+RY NTVEVELPV+KAI QF+SGKS  DDLFDKLDTSKLNA
Sbjct: 638  NVKAVPPNLLEFNFLGKDSIRYENTVEVELPVFKAITQFQSGKSGTDDLFDKLDTSKLNA 697

Query: 939  HLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSV 760
            HLK+LMPGLTAKVFRTYNASITLD+MLNR TK+GEV+EKIV YQHANKEVAIICNHQR+V
Sbjct: 698  HLKDLMPGLTAKVFRTYNASITLDDMLNRGTKNGEVSEKIVTYQHANKEVAIICNHQRTV 757

Query: 759  SKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIA 580
            SKSH AQM+RL+EK+ EL+ +L ELK DL RAKKGKPPL  +DGK K+NLTPEALEKKI+
Sbjct: 758  SKSHGAQMTRLNEKISELRDILKELKIDLDRAKKGKPPLKGSDGKQKRNLTPEALEKKIS 817

Query: 579  QTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKF 400
            QTN KIEK+ERDMKTKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAKF
Sbjct: 818  QTNAKIEKIERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF 877

Query: 399  AWSMDVDPTFRF 364
            AW+MDVDP FRF
Sbjct: 878  AWAMDVDPDFRF 889



 Score = 82.4 bits (202), Expect = 9e-13
 Identities = 48/119 (40%), Positives = 75/119 (63%), Gaps = 5/119 (4%)
 Frame = -3

Query: 2526 SSEDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVL 2347
            S  DS+DE+P S +F+ K  +G    K +  +E+KP   K+ QNGS     + ++ P VL
Sbjct: 175  SLADSDDEVPLSSKFQMKHASGVLGSKQHGFDEKKPLVPKVHQNGST--SRDKLQKPAVL 232

Query: 2346 -NKRTL--SDANPSAQCPIKKQKLSD--IPVHGKIGQAHVKAEQKIEDDDDDVPLSQRM 2185
             +KR L   D++  +Q P KK KL+D   P++ K+    +KA+Q+++DDDDD+P+SQRM
Sbjct: 233  SSKRPLPNEDSHSPSQFPTKKPKLTDSSSPLNSKL--VSLKAKQEVDDDDDDIPISQRM 289


>ref|NP_001157806.1| topoisomerase I [Zea mays] gi|240065169|gb|ACS44671.1| DNA
            topoisomerase I [Zea mays]
          Length = 904

 Score =  923 bits (2386), Expect = 0.0
 Identities = 475/728 (65%), Positives = 543/728 (74%), Gaps = 9/728 (1%)
 Frame = -3

Query: 2520 EDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFA---SKIQQNG------SIKGGNEL 2368
            EDS+D+ P + R    +G  S  +   DS +EKP A   SK+  +G      S KG    
Sbjct: 190  EDSDDDKPLASRLPSNAGPKSGGDVSEDSEDEKPLAARFSKVAGSGNPKIASSSKGLTSD 249

Query: 2367 VKSPKVLNKRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQR 2188
                + L KR L  +N ++   +KK K S++        A V+ E K    DD+ PL+QR
Sbjct: 250  TNGQQSLGKRPLDSSNQTSSA-LKKAKPSNVSA-----SAIVRREIKT---DDNTPLAQR 300

Query: 2187 MXXXXXXXXXXXXXXXXKVFFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPSF 2008
            +                   F                                  VPP  
Sbjct: 301  LKMGESSKGKSSAKSV----FKKSPVSVKKDIKKMKGKGKLKKNMKNSQFSKIMKVPPGS 356

Query: 2007 GEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYATKPR 1828
            G GKKW+TLEHNGVIFPPPYK HGVKMLYNG+PVDLTPEQEEVATMFAVMKDT+YA KP 
Sbjct: 357  GGGKKWTTLEHNGVIFPPPYKPHGVKMLYNGKPVDLTPEQEEVATMFAVMKDTDYAAKPT 416

Query: 1827 FIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXXXXXX 1648
            FI+NF  DWR +LGKNHIIK FELC+FTPIYEWHL EKE+KKQM+T              
Sbjct: 417  FIDNFFTDWRKVLGKNHIIKNFELCDFTPIYEWHLREKERKKQMTTEEKKTLREDNLKQE 476

Query: 1647 XKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPEC 1468
             KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRI PSDITINIGK AP+PEC
Sbjct: 477  EKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRILPSDITINIGKGAPVPEC 536

Query: 1467 PIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARVLKDY 1288
            PIPG+ WKEVKHDNTVTWLAFWNDPINPK+FKYVFLAASSSLKGQSDKEKYEK+R LK +
Sbjct: 537  PIPGESWKEVKHDNTVTWLAFWNDPINPKDFKYVFLAASSSLKGQSDKEKYEKSRKLKGH 596

Query: 1287 IHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEL 1108
            I  IR  YTKDF +KD+T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV+NV  
Sbjct: 597  IQRIRENYTKDFKNKDVTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNVTC 656

Query: 1107 VPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNAHLKE 928
            +PPN++QFDFLGKDS+RYFNTVEVE  VYKAI  F++GK  G DLFDK+DTS+LNAHLK+
Sbjct: 657  MPPNQIQFDFLGKDSIRYFNTVEVEELVYKAIEGFRAGKKPGQDLFDKIDTSRLNAHLKD 716

Query: 927  LMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSVSKSH 748
            LMPGLTAKVFRTYNASITLD +L+ ET+DG V EKI +YQ ANKEVAIICN QRSVSKSH
Sbjct: 717  LMPGLTAKVFRTYNASITLDGILHEETEDGTVLEKIAVYQRANKEVAIICNQQRSVSKSH 776

Query: 747  SAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIAQTNV 568
             +QM+R++EK+DELK+ ++ELK DL +AKKGKP   D++GKPK+NL PEA++KK+A    
Sbjct: 777  ESQMTRMNEKIDELKSQMEELKADLNKAKKGKPLGYDSEGKPKRNLAPEAIQKKVATLEG 836

Query: 567  KIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWSM 388
            KIEKME D + KEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAKF W+M
Sbjct: 837  KIEKMEMDKRIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFVWAM 896

Query: 387  DVDPTFRF 364
            DVDP FRF
Sbjct: 897  DVDPEFRF 904


>gb|EMS46223.1| DNA topoisomerase 1 [Triticum urartu]
          Length = 947

 Score =  920 bits (2377), Expect = 0.0
 Identities = 469/721 (65%), Positives = 537/721 (74%)
 Frame = -3

Query: 2526 SSEDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVL 2347
            S+ DSEDE P S RF    G   +S    +S ++ P  +K   N S    N  VK P   
Sbjct: 251  STSDSEDEKPLSARFS--RGTAGTSASISNSKDKLPSNNKGPTNNSSAPRNS-VKRPGYN 307

Query: 2346 NKRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQRMXXXXXX 2167
            N +T S         +KK K SD    G + +      +  +DD + VP+ +++      
Sbjct: 308  NNQTSS--------ALKKTKSSDASASGSVKR------ESTDDDSNSVPVERKLTPGESS 353

Query: 2166 XXXXXXXXXXKVFFDXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPSFGEGKKWS 1987
                          +                                 VPP  G GKKWS
Sbjct: 354  KSKPPVK-------NIVKSPLSVKKDNKKFKTKTKKTMKSSQFSKSLRVPPGSGGGKKWS 406

Query: 1986 TLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYATKPRFIENFMN 1807
            TLEHNGVIFPPPY  HGVKMLYNGQPV+LTPE+EEVATMFAVMKDTEYATK  FI+NF  
Sbjct: 407  TLEHNGVIFPPPYNPHGVKMLYNGQPVELTPEEEEVATMFAVMKDTEYATKKTFIDNFFG 466

Query: 1806 DWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXXXXXXXKYMWAI 1627
            DW+ ILGKNHIIKKFELC+FTPIYEWHL EKEKKKQM++               KYMWA+
Sbjct: 467  DWKKILGKNHIIKKFELCDFTPIYEWHLREKEKKKQMTSEEKKALREEKLKQEEKYMWAV 526

Query: 1626 VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGQRW 1447
            VDGV+EKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGK  P+PECPI GQ W
Sbjct: 527  VDGVREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGTPVPECPIEGQSW 586

Query: 1446 KEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARVLKDYIHDIRAT 1267
            KEVKHDNTVTWLAFWNDPI+ K+FKYVFLAASSSLKGQSDKEKYEK+R LKD+IH+IR  
Sbjct: 587  KEVKHDNTVTWLAFWNDPISQKDFKYVFLAASSSLKGQSDKEKYEKSRKLKDHIHNIRVN 646

Query: 1266 YTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVELVPPNKLQ 1087
            YTKDF SKD++K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV+NV  VPPNKLQ
Sbjct: 647  YTKDFNSKDVSKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVDNVTCVPPNKLQ 706

Query: 1086 FDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNAHLKELMPGLTA 907
            FDFLGKDS+RYFNTVEVELPVY AI +F++GK +GD +FD+LDT+KLN HLK+LMPGLTA
Sbjct: 707  FDFLGKDSIRYFNTVEVELPVYNAIEEFRTGKKDGDAVFDQLDTTKLNHHLKDLMPGLTA 766

Query: 906  KVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSVSKSHSAQMSRL 727
            KVFRTYNASITLD +L+ ET+DG + EKI +YQ ANKEVAIICNHQR+VSKSH  QM++L
Sbjct: 767  KVFRTYNASITLDAILHEETEDGTLLEKIAVYQRANKEVAIICNHQRAVSKSHDTQMTKL 826

Query: 726  SEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIAQTNVKIEKMER 547
            +EK+DELKA +DEL  DL + K+GKP  N ADGKPK+ L PEA+EKKI+Q   KIEKME 
Sbjct: 827  NEKIDELKAQVDELNKDLGKVKRGKPLGNGADGKPKRTLAPEAIEKKISQIETKIEKMEM 886

Query: 546  DMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWSMDVDPTFR 367
            D KTKEDLKTVALGTSKINYLDPRI+VAWCK HEVPIEKIF+K++LAKF W+MDV+P FR
Sbjct: 887  DKKTKEDLKTVALGTSKINYLDPRITVAWCKTHEVPIEKIFSKTILAKFGWAMDVEPDFR 946

Query: 366  F 364
            F
Sbjct: 947  F 947


>ref|XP_006659124.1| PREDICTED: DNA topoisomerase 1-like [Oryza brachyantha]
          Length = 911

 Score =  916 bits (2368), Expect = 0.0
 Identities = 442/552 (80%), Positives = 487/552 (88%)
 Frame = -3

Query: 2019 PPSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYA 1840
            PP  G G+KW+TL HNGVIFPPPYK HGVKMLYNGQPVDLTPEQEEVATMF+VMKDT+YA
Sbjct: 360  PPGSGGGQKWTTLVHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFSVMKDTDYA 419

Query: 1839 TKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXX 1660
            +K  FI+NF  DWR ILGKNHIIKKFELC+FTPIYEWHL EKEKKKQM++          
Sbjct: 420  SKQTFIDNFFTDWRKILGKNHIIKKFELCDFTPIYEWHLREKEKKKQMTSEEKKAVKEEK 479

Query: 1659 XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1480
                 KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRI+PSDITINIGK AP
Sbjct: 480  LKQEEKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIQPSDITINIGKGAP 539

Query: 1479 IPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARV 1300
            IPECPIPG+ WKEVKHDNTVTWLAFWNDPI+ K+FKYVFLAASS+LKGQSDKEKYEK+R 
Sbjct: 540  IPECPIPGESWKEVKHDNTVTWLAFWNDPISQKDFKYVFLAASSALKGQSDKEKYEKSRK 599

Query: 1299 LKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 1120
            LK +IH IR TYTKDF SKD TK+QIAVATYLIDKLALRAGNEKDDDEA+TVGCCTLKV+
Sbjct: 600  LKHHIHKIRDTYTKDFRSKDKTKKQIAVATYLIDKLALRAGNEKDDDEAETVGCCTLKVD 659

Query: 1119 NVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNA 940
            NV  VPPN LQFDFLGKDS+RYFNTVEVELPVYKAI +F++GK  GDDLFDKLDT++LNA
Sbjct: 660  NVTCVPPNNLQFDFLGKDSIRYFNTVEVELPVYKAIEEFRAGKKPGDDLFDKLDTTRLNA 719

Query: 939  HLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSV 760
            HLK+LMPGLTAKVFRTYNASITLD++L++ET+DG + EKI +YQ ANKEVAIICNHQRSV
Sbjct: 720  HLKDLMPGLTAKVFRTYNASITLDDILHKETEDGTLLEKIAVYQRANKEVAIICNHQRSV 779

Query: 759  SKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIA 580
            SKSH +QM+RL+EK+DELKA  DELK DL + KKGK    D DGKPK+NL PEA EKKI+
Sbjct: 780  SKSHDSQMTRLNEKIDELKAQRDELKADLSKVKKGKSLGYDKDGKPKRNLAPEAFEKKIS 839

Query: 579  QTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKF 400
            Q   KIEKME D K KEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSL+AKF
Sbjct: 840  QVETKIEKMEMDKKIKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLIAKF 899

Query: 399  AWSMDVDPTFRF 364
            +W+MDVDP FRF
Sbjct: 900  SWAMDVDPDFRF 911


>ref|XP_007201211.1| hypothetical protein PRUPE_ppa001622mg [Prunus persica]
            gi|462396611|gb|EMJ02410.1| hypothetical protein
            PRUPE_ppa001622mg [Prunus persica]
          Length = 790

 Score =  914 bits (2363), Expect = 0.0
 Identities = 442/553 (79%), Positives = 493/553 (89%), Gaps = 1/553 (0%)
 Frame = -3

Query: 2019 PPSFGEG-KKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEY 1843
            PPS  +G KKW++L HNGVIFPPPYK HGVKMLY+G+PV L+PEQEEVATM+AVMKDT+Y
Sbjct: 238  PPSSNDGQKKWTSLVHNGVIFPPPYKPHGVKMLYSGKPVTLSPEQEEVATMYAVMKDTDY 297

Query: 1842 ATKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXX 1663
              K  F  NF NDW  +LGKNHII+K + C+FTPIY+W+ NEKEKKKQMST         
Sbjct: 298  VQKQTFRNNFWNDWHKLLGKNHIIQKLDACDFTPIYDWYQNEKEKKKQMSTEEKKALKED 357

Query: 1662 XXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDA 1483
                  KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPK GKLKRRIRPSD+TINIGKDA
Sbjct: 358  KLKEEEKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKSGKLKRRIRPSDVTINIGKDA 417

Query: 1482 PIPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 1303
            PIPECPIPG+ WKEV+HDNTVTWLAFWNDPIN +EFKYVFLA SSSLKGQSDKEKYEKAR
Sbjct: 418  PIPECPIPGESWKEVRHDNTVTWLAFWNDPINQREFKYVFLAPSSSLKGQSDKEKYEKAR 477

Query: 1302 VLKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 1123
            +LKDYI +IRA YT+DF SKD TKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 478  MLKDYIGNIRAAYTRDFTSKDGTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 537

Query: 1122 ENVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLN 943
            ENV+ + PN L+F+FLGKDS+RY NTVEVE+PVYKAI QF++GK   DDLFD+LDTSKLN
Sbjct: 538  ENVKAIAPNSLEFNFLGKDSIRYENTVEVEIPVYKAIIQFQTGKRGCDDLFDRLDTSKLN 597

Query: 942  AHLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRS 763
            AHLKELMPGLTAKVFRTYNASITLD +LN+ETK+G+++EK+V+YQHANKEVAIICNHQR+
Sbjct: 598  AHLKELMPGLTAKVFRTYNASITLDNILNKETKEGDLSEKVVVYQHANKEVAIICNHQRT 657

Query: 762  VSKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKI 583
            +SK+HSAQMSRL EK+  L+++L ELKTDL RAKKG+PPL DADGK K+NLTPEALE+KI
Sbjct: 658  ISKTHSAQMSRLLEKIGNLQSILKELKTDLDRAKKGRPPLKDADGKQKRNLTPEALERKI 717

Query: 582  AQTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAK 403
            AQT VKIEKME DM+TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAK
Sbjct: 718  AQTTVKIEKMELDMRTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAK 777

Query: 402  FAWSMDVDPTFRF 364
            FAWSMDVDP FRF
Sbjct: 778  FAWSMDVDPDFRF 790



 Score = 68.6 bits (166), Expect = 1e-08
 Identities = 49/115 (42%), Positives = 61/115 (53%), Gaps = 3/115 (2%)
 Frame = -3

Query: 2520 EDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSI---KGGNELVKSPKV 2350
            EDS+D+ P S R   K   G+S  +  DS E KP ASK+Q+N S    KG    V S   
Sbjct: 82   EDSDDDKPLSSRITPKK-VGTSGSQPCDSKERKPVASKVQKNCSSTTDKGKTSYVIS--- 137

Query: 2349 LNKRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQRM 2185
              KR L  AN S +   K+ K+SD     K  Q   K E K EDDDD +P+SQR+
Sbjct: 138  -TKRPLDKANISEKSSAKRPKVSDSSTSIKNMQVSAKKEPKGEDDDDFIPISQRI 191


>ref|XP_004972822.1| PREDICTED: DNA topoisomerase 1-like isoform X3 [Setaria italica]
          Length = 903

 Score =  913 bits (2360), Expect = 0.0
 Identities = 439/552 (79%), Positives = 486/552 (88%)
 Frame = -3

Query: 2019 PPSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYA 1840
            PP  G GKKW+TLEHNGVIFPPPYK HGVKMLYNGQPVDLTPEQEEVATMFAVMKDT+YA
Sbjct: 352  PPGSGGGKKWTTLEHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYA 411

Query: 1839 TKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXX 1660
             KP FIENF  DWR +LGKNH+IKKFELC+FTPIYEWHL EKEKKKQM+T          
Sbjct: 412  GKPTFIENFFTDWRTLLGKNHVIKKFELCDFTPIYEWHLREKEKKKQMTTEEKKALREEK 471

Query: 1659 XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1480
                 KYMWA+VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRI+PSDITINIG+DAP
Sbjct: 472  LKQEEKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIKPSDITINIGEDAP 531

Query: 1479 IPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARV 1300
            +PECPIPG+RWKEVKHDNTVTWLAFWNDPI+ K+FKYVFLAASSSLKGQSDKEKYEK+R 
Sbjct: 532  VPECPIPGERWKEVKHDNTVTWLAFWNDPISQKDFKYVFLAASSSLKGQSDKEKYEKSRK 591

Query: 1299 LKDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 1120
            LK YI DIR  YTKDF SKD+ KRQIAVATYLIDKLALRAGNEKD+DEADTVGCCTLKV+
Sbjct: 592  LKGYIQDIRDNYTKDFRSKDVAKRQIAVATYLIDKLALRAGNEKDEDEADTVGCCTLKVD 651

Query: 1119 NVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNA 940
            NV  +PPNK+QFDFLGKDS+RYFNTVEVE  VYKAI  F++GK  G DLFD+LDT++LNA
Sbjct: 652  NVTCLPPNKIQFDFLGKDSIRYFNTVEVEELVYKAIEGFRAGKKPGKDLFDQLDTTRLNA 711

Query: 939  HLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSV 760
            HLK+LMPGLTAKVFRTYNASITLD +L++ET+DG + EKI +YQ ANKEVAIICNHQRSV
Sbjct: 712  HLKDLMPGLTAKVFRTYNASITLDGILHKETEDGTLLEKIAVYQRANKEVAIICNHQRSV 771

Query: 759  SKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIA 580
            SKSH +QM+RL+E++D+LKA  DELK DL +AKKGKP   D +GK K+NL P+A+EKKIA
Sbjct: 772  SKSHESQMTRLNERIDDLKAQRDELKVDLSKAKKGKPLGYDKEGKQKRNLAPDAIEKKIA 831

Query: 579  QTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKF 400
                KIEKME + KTKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSL+AKF
Sbjct: 832  AIETKIEKMEMEKKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLVAKF 891

Query: 399  AWSMDVDPTFRF 364
             W+MDVDP FRF
Sbjct: 892  GWAMDVDPEFRF 903


>ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Solanum
            tuberosum]
          Length = 905

 Score =  912 bits (2356), Expect = 0.0
 Identities = 441/551 (80%), Positives = 487/551 (88%)
 Frame = -3

Query: 2016 PSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYAT 1837
            PS G+G+KW+TLEHNGVIFPPPYK HGVKMLY G+PVDLTPEQEEVATM+AVM DTEY T
Sbjct: 355  PSSGDGQKWTTLEHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTEYLT 414

Query: 1836 KPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXXX 1657
            K +F ENFMNDWR ILGKNH+I+K E CNFTPIYEWH +EKEKKKQMS+           
Sbjct: 415  KQQFKENFMNDWRKILGKNHVIQKLEECNFTPIYEWHQSEKEKKKQMSSEEKKALREEKL 474

Query: 1656 XXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPI 1477
                KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRP+DITINIGK  P+
Sbjct: 475  KQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGVPV 534

Query: 1476 PECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARVL 1297
            PECPIPGQRWKEV+HDNTVTWLAFWNDPINP+EFKYVFLAASSSLKGQSDKEKYEKAR L
Sbjct: 535  PECPIPGQRWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARRL 594

Query: 1296 KDYIHDIRATYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN 1117
            KDYI  IR+ YTKDF SKD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN
Sbjct: 595  KDYIEGIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN 654

Query: 1116 VELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLNAH 937
            VE VPPN L+FDFLGKDS+RY N V V  PV+KAI QF+SGK  GDDLFDKLDTSKLNAH
Sbjct: 655  VEPVPPNILKFDFLGKDSIRYQNEVAVYEPVFKAIQQFRSGKKGGDDLFDKLDTSKLNAH 714

Query: 936  LKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRSVS 757
            LKELMPGLTAKVFRTYNAS TL++ L + T+ GE+A+K+ +Y  ANKEVAIICNHQR+VS
Sbjct: 715  LKELMPGLTAKVFRTYNASFTLEQQLTKLTQGGELADKVAVYNVANKEVAIICNHQRTVS 774

Query: 756  KSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKIAQ 577
            KSHS Q+SRL+EK+DELKA+L+E K DL RAKKGKPP+  ADGK K+NLTPEAL+KKI Q
Sbjct: 775  KSHSVQISRLNEKIDELKAILEEFKVDLARAKKGKPPVKGADGKAKRNLTPEALQKKIDQ 834

Query: 576  TNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFA 397
            TNVKI+ +ER ++TKE+LKTVALGTSKINYLDPRI+VAWCKRHEVPIEK+FNKSLLAKFA
Sbjct: 835  TNVKIDNIERQIETKEELKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLAKFA 894

Query: 396  WSMDVDPTFRF 364
            W+MDV+P+F F
Sbjct: 895  WAMDVEPSFTF 905



 Score = 72.0 bits (175), Expect = 1e-09
 Identities = 48/115 (41%), Positives = 65/115 (56%), Gaps = 3/115 (2%)
 Frame = -3

Query: 2520 EDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLNK 2341
            EDS+DEIP + RF+ KS AG+S+ KF  S E KP   KI+QNG        + S  VL+K
Sbjct: 207  EDSDDEIPLASRFQMKSSAGASTSKFSSSEEVKP---KIRQNG--------LPSATVLSK 255

Query: 2340 RTLSDANPSAQCPIKKQKLSDIPVH---GKIGQAHVKAEQKIEDDDDDVPLSQRM 2185
            R   + +   +  +K     D  +H     +    VK E+K EDDDD+VPLSQR+
Sbjct: 256  RPPGEVSLLLRLQLKS---LDFLMHLHLFLVSNXSVKTEKKTEDDDDEVPLSQRI 307


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score =  911 bits (2355), Expect = 0.0
 Identities = 446/553 (80%), Positives = 486/553 (87%), Gaps = 1/553 (0%)
 Frame = -3

Query: 2019 PPSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYA 1840
            PP  GEG+KW+TL HNGVIFPPPYK HGVKMLY  QP+ LTPEQEEVATMFAVM DT+Y 
Sbjct: 373  PPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDYM 432

Query: 1839 TKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXX 1660
             KP F ENF +DW+ ILGKNH+I+  E C+F PIYEWH  EKEKKKQM+T          
Sbjct: 433  NKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEEK 492

Query: 1659 XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1480
                 KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP DITINIGKDAP
Sbjct: 493  LQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAP 552

Query: 1479 IPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARV 1300
            IPECPIPG+RWKEV++ NTVTWLA+WNDPIN KEFKYVFLAASS+LKGQSDKEKYEKAR+
Sbjct: 553  IPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKEKYEKARL 612

Query: 1299 LKDYIHDIRATYTKDFAS-KDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 1123
            LKDYIH IRA YTKDF + KD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 613  LKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 672

Query: 1122 ENVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLN 943
            ENVE VPPN L+FDFLGKDS+RY N V+VE  V+KAI QF+SGK   +DLFD+LDTSKLN
Sbjct: 673  ENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLN 732

Query: 942  AHLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRS 763
            AHLKELMPGLTAKVFRTYNASITLD+ML++ETK GEVAE +V+YQHANKEVAIICNHQR+
Sbjct: 733  AHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVVYQHANKEVAIICNHQRT 792

Query: 762  VSKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKI 583
            VSKSHSAQMSRL+EK+DELK  L+ELKTDL RAKKGKPP   ADGK K+NL PEALE+KI
Sbjct: 793  VSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGADGKAKRNLNPEALERKI 852

Query: 582  AQTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAK 403
             QTN KIEKMERD +TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAK
Sbjct: 853  TQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAK 912

Query: 402  FAWSMDVDPTFRF 364
            FAWSMDVDP+FRF
Sbjct: 913  FAWSMDVDPSFRF 925



 Score =  102 bits (254), Expect = 9e-19
 Identities = 57/112 (50%), Positives = 68/112 (60%)
 Frame = -3

Query: 2523 SEDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLN 2344
            SEDSEDE P S RF  KS  G S+ K YDS+E+KP A+K+QQNGS      + KS  + N
Sbjct: 189  SEDSEDEKPLSCRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSASLSN 248

Query: 2343 KRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVKAEQKIEDDDDDVPLSQR 2188
            KR   +A    Q  +KK KLS         QA VK E K EDDDD++PLSQR
Sbjct: 249  KRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQR 300


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score =  911 bits (2355), Expect = 0.0
 Identities = 445/553 (80%), Positives = 486/553 (87%), Gaps = 1/553 (0%)
 Frame = -3

Query: 2019 PPSFGEGKKWSTLEHNGVIFPPPYKSHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYA 1840
            PP  GEG+KW+TL HNGVIFPPPY  HGVKMLY  QP+ LTPEQEEVATMFAVM DT+Y 
Sbjct: 375  PPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDYM 434

Query: 1839 TKPRFIENFMNDWRLILGKNHIIKKFELCNFTPIYEWHLNEKEKKKQMSTXXXXXXXXXX 1660
             KPRF ENF +DW+ +LGKNH I+  E C+F PIYEWH  EKEKKKQM+T          
Sbjct: 435  NKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEDK 494

Query: 1659 XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAP 1480
                 KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP DITINIGKDAP
Sbjct: 495  LQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAP 554

Query: 1479 IPECPIPGQRWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARV 1300
            IPECPIPG+RWKEV++DNTVTWLAFW DPIN KEFKYVFLAASS+LKGQSDKEKYEKAR+
Sbjct: 555  IPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASSTLKGQSDKEKYEKARL 614

Query: 1299 LKDYIHDIRATYTKDFAS-KDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 1123
            LKDYIH IRA YTKDF + KD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 615  LKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 674

Query: 1122 ENVELVPPNKLQFDFLGKDSVRYFNTVEVELPVYKAIGQFKSGKSEGDDLFDKLDTSKLN 943
            ENVE VPPN L+FDFLGKDS+RY N V+VE  V+KAI QF+SGK   +DLFD+LDTSKLN
Sbjct: 675  ENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLN 734

Query: 942  AHLKELMPGLTAKVFRTYNASITLDEMLNRETKDGEVAEKIVIYQHANKEVAIICNHQRS 763
            AHLKELMPGLTAKVFRTYNASITLD+ML++ETK GEVAEK+V+YQHANKEVAIICNHQR+
Sbjct: 735  AHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVYQHANKEVAIICNHQRT 794

Query: 762  VSKSHSAQMSRLSEKMDELKAVLDELKTDLVRAKKGKPPLNDADGKPKKNLTPEALEKKI 583
            VSKSHSAQMSRL+EK+DELK  ++ELKTDL R KKGKPP   ADGKPK+NL PEALE+K+
Sbjct: 795  VSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSKGADGKPKRNLNPEALERKM 854

Query: 582  AQTNVKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAK 403
            AQ N KIEKMERD +TKEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAK
Sbjct: 855  AQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAK 914

Query: 402  FAWSMDVDPTFRF 364
            FAWSMDVDP+FRF
Sbjct: 915  FAWSMDVDPSFRF 927



 Score = 97.1 bits (240), Expect = 4e-17
 Identities = 56/114 (49%), Positives = 68/114 (59%), Gaps = 2/114 (1%)
 Frame = -3

Query: 2523 SEDSEDEIPFSLRFKFKSGAGSSSEKFYDSNEEKPFASKIQQNGSIKGGNELVKSPKVLN 2344
            SEDSEDE P S RF  KS  G S+ K YDS+E+KP A+K+QQNGS+     + KS  + N
Sbjct: 189  SEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSVSRDGPMNKSASLSN 248

Query: 2343 KRTLSDANPSAQCPIKKQKLSDIPVHGKIGQAHVK--AEQKIEDDDDDVPLSQR 2188
            KR   +     Q  +KK KLS         QA VK   E K EDDDD++PLSQR
Sbjct: 249  KRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIPLSQR 302