BLASTX nr result
ID: Akebia22_contig00028468
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Akebia22_contig00028468
(238 letters)
Database: ./nr
38,876,450 sequences; 13,856,398,315 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_007049497.1| Cytochrome b561/ferric reductase transmembra... 110 2e-22
ref|XP_003548431.1| PREDICTED: uncharacterized protein LOC100804... 110 2e-22
ref|XP_003529906.1| PREDICTED: uncharacterized protein LOC100803... 110 2e-22
ref|XP_007135210.1| hypothetical protein PHAVU_010G110300g [Phas... 108 6e-22
ref|XP_004510729.1| PREDICTED: uncharacterized protein LOC101514... 106 3e-21
ref|XP_006366806.1| PREDICTED: uncharacterized protein LOC102589... 105 5e-21
ref|XP_004242458.1| PREDICTED: uncharacterized protein LOC101263... 105 5e-21
ref|XP_003637246.1| Ferric-chelate reductase [Medicago truncatul... 105 5e-21
gb|EXB40467.1| Putative ferric-chelate reductase 1 [Morus notabi... 103 2e-20
ref|XP_004246246.1| PREDICTED: ferric-chelate reductase 1-like i... 100 4e-19
ref|XP_004246245.1| PREDICTED: ferric-chelate reductase 1-like i... 100 4e-19
ref|XP_003635609.1| PREDICTED: uncharacterized protein LOC100853... 100 4e-19
ref|XP_002270178.2| PREDICTED: putative ferric-chelate reductase... 100 4e-19
emb|CBI38284.3| unnamed protein product [Vitis vinifera] 100 4e-19
ref|XP_006469476.1| PREDICTED: uncharacterized protein LOC102623... 99 8e-19
ref|XP_006447897.1| hypothetical protein CICLE_v10015681mg [Citr... 99 8e-19
ref|XP_006344352.1| PREDICTED: uncharacterized protein LOC102596... 98 1e-18
ref|NP_566313.2| Cytochrome b561/ferric reductase transmembrane ... 97 3e-18
ref|XP_002884658.1| predicted protein [Arabidopsis lyrata subsp.... 97 3e-18
gb|AAF13075.1|AC009176_2 unknown protein [Arabidopsis thaliana] 97 3e-18
>ref|XP_007049497.1| Cytochrome b561/ferric reductase transmembrane with DOMON related
domain, putative [Theobroma cacao]
gi|508701758|gb|EOX93654.1| Cytochrome b561/ferric
reductase transmembrane with DOMON related domain,
putative [Theobroma cacao]
Length = 364
Score = 110 bits (276), Expect = 2e-22
Identities = 48/78 (61%), Positives = 67/78 (85%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W+FVLSAP+ NS++A+GFS+NG MVGSSAMVGW+ +G+ IKQY+LG T N V+PDQ
Sbjct: 67 LWSFVLSAPDKNSFVAMGFSSNGMMVGSSAMVGWISTDGTATIKQYFLGGTRSNLVLPDQ 126
Query: 183 GSLSIVSNSTTVISQSSR 236
G+L++V+NS+++ SQSSR
Sbjct: 127 GNLTVVNNSSSITSQSSR 144
>ref|XP_003548431.1| PREDICTED: uncharacterized protein LOC100804791 [Glycine max]
Length = 562
Score = 110 bits (275), Expect = 2e-22
Identities = 52/79 (65%), Positives = 65/79 (82%), Gaps = 1/79 (1%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGS-GVIKQYYLGATNPNQVIPD 179
IW+F+LSAPN NSYIAIGFS NG MVGSSA+VGW+ NG+ G +KQYYL PNQV+PD
Sbjct: 263 IWSFILSAPNPNSYIAIGFSPNGGMVGSSAIVGWISSNGAGGGMKQYYLTGLTPNQVVPD 322
Query: 180 QGSLSIVSNSTTVISQSSR 236
+G+L +++NST + SQSSR
Sbjct: 323 RGNLKVLTNSTFITSQSSR 341
Score = 109 bits (272), Expect = 5e-22
Identities = 52/78 (66%), Positives = 61/78 (78%), Gaps = 1/78 (1%)
Frame = +3
Query: 6 WNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNG-SGVIKQYYLGATNPNQVIPDQ 182
W+F+LS P+TNSYIAIGFS G MVGSSAMVGWV G SG IKQYYLG PNQV+PD+
Sbjct: 72 WSFILSTPDTNSYIAIGFSAGGGMVGSSAMVGWVASRGASGGIKQYYLGGVTPNQVVPDK 131
Query: 183 GSLSIVSNSTTVISQSSR 236
G+L ++ NST + QSSR
Sbjct: 132 GNLQVIDNSTFITLQSSR 149
>ref|XP_003529906.1| PREDICTED: uncharacterized protein LOC100803524 [Glycine max]
Length = 558
Score = 110 bits (275), Expect = 2e-22
Identities = 52/79 (65%), Positives = 65/79 (82%), Gaps = 1/79 (1%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGS-GVIKQYYLGATNPNQVIPD 179
IW+F+LSAPN NSYIAIGFS NG MVGSSA+VGW+ NG+ G +KQYYL PNQV+PD
Sbjct: 258 IWSFILSAPNPNSYIAIGFSPNGGMVGSSAIVGWISSNGAGGGMKQYYLTGLTPNQVVPD 317
Query: 180 QGSLSIVSNSTTVISQSSR 236
+G+L +++NST + SQSSR
Sbjct: 318 RGNLKVLTNSTFITSQSSR 336
Score = 108 bits (269), Expect = 1e-21
Identities = 51/78 (65%), Positives = 61/78 (78%), Gaps = 1/78 (1%)
Frame = +3
Query: 6 WNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNG-SGVIKQYYLGATNPNQVIPDQ 182
W+F+LS P+TNSYIA+GFS G MVGSSAMVGWV G SG IKQYYLG PNQV+PD+
Sbjct: 67 WSFILSTPDTNSYIAMGFSVGGGMVGSSAMVGWVASRGASGGIKQYYLGGVTPNQVVPDK 126
Query: 183 GSLSIVSNSTTVISQSSR 236
G+L ++ NST + QSSR
Sbjct: 127 GNLQVIDNSTFITLQSSR 144
>ref|XP_007135210.1| hypothetical protein PHAVU_010G110300g [Phaseolus vulgaris]
gi|561008255|gb|ESW07204.1| hypothetical protein
PHAVU_010G110300g [Phaseolus vulgaris]
Length = 555
Score = 108 bits (271), Expect = 6e-22
Identities = 51/79 (64%), Positives = 66/79 (83%), Gaps = 1/79 (1%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGS-GVIKQYYLGATNPNQVIPD 179
IW+F+LSAPNTNSYIA+GFS NG MVGSSA+VGW+ +G+ G +KQYYL PNQV+PD
Sbjct: 257 IWSFILSAPNTNSYIAMGFSPNGGMVGSSAIVGWISSSGAGGGMKQYYLTGLAPNQVVPD 316
Query: 180 QGSLSIVSNSTTVISQSSR 236
+G+L +++NST + SQSSR
Sbjct: 317 RGNLKVLTNSTFITSQSSR 335
Score = 107 bits (267), Expect = 2e-21
Identities = 51/79 (64%), Positives = 63/79 (79%), Gaps = 1/79 (1%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNG-SGVIKQYYLGATNPNQVIPD 179
IW+F+LS P+TNSYIA+GFS +G MVGSSAMVGWV G SG IKQYYLG NQV+PD
Sbjct: 65 IWSFILSTPDTNSYIAMGFSVSGGMVGSSAMVGWVASRGASGGIKQYYLGGVTSNQVVPD 124
Query: 180 QGSLSIVSNSTTVISQSSR 236
+G+L +++NST + QSSR
Sbjct: 125 KGNLQVIANSTFITLQSSR 143
>ref|XP_004510729.1| PREDICTED: uncharacterized protein LOC101514851 [Cicer arietinum]
Length = 554
Score = 106 bits (265), Expect = 3e-21
Identities = 50/78 (64%), Positives = 63/78 (80%), Gaps = 1/78 (1%)
Frame = +3
Query: 6 WNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNG-SGVIKQYYLGATNPNQVIPDQ 182
W+F+L+APN NSYIAIGFS NG MV SSA+VGW+ NG SG +KQYYL PNQV+P++
Sbjct: 257 WSFILTAPNQNSYIAIGFSPNGGMVSSSAIVGWISSNGASGGMKQYYLAGYAPNQVVPNR 316
Query: 183 GSLSIVSNSTTVISQSSR 236
G+L ++SNST + SQSSR
Sbjct: 317 GNLQVISNSTLITSQSSR 334
Score = 103 bits (256), Expect = 3e-20
Identities = 48/79 (60%), Positives = 61/79 (77%), Gaps = 1/79 (1%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNG-SGVIKQYYLGATNPNQVIPD 179
IW+F+LS P+TNSY+A+GFS G MVGSSA+VGWV G +G IKQYYLG NQV+PD
Sbjct: 65 IWSFILSTPDTNSYVAMGFSATGGMVGSSAIVGWVASKGANGGIKQYYLGGVTSNQVVPD 124
Query: 180 QGSLSIVSNSTTVISQSSR 236
+G+L ++ NST + QSSR
Sbjct: 125 KGNLQVIGNSTFISLQSSR 143
>ref|XP_006366806.1| PREDICTED: uncharacterized protein LOC102589215 [Solanum tuberosum]
Length = 374
Score = 105 bits (263), Expect = 5e-21
Identities = 44/78 (56%), Positives = 68/78 (87%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W++VLSAPNTNSYIA+GFS GKMVGS+A+VGWV +G+ +K+Y+LG +PNQV+PD+
Sbjct: 77 VWSYVLSAPNTNSYIAMGFSEKGKMVGSTAIVGWVSNDGTATMKKYFLGGQSPNQVLPDE 136
Query: 183 GSLSIVSNSTTVISQSSR 236
G+L +V+ +++V++++SR
Sbjct: 137 GNLQLVNFTSSVVAENSR 154
>ref|XP_004242458.1| PREDICTED: uncharacterized protein LOC101263424 [Solanum
lycopersicum]
Length = 374
Score = 105 bits (263), Expect = 5e-21
Identities = 44/78 (56%), Positives = 68/78 (87%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W++VLSAPNTNSYIA+GFS GKMVGS+A+VGWV +G+ +K+Y+LG +PNQV+PD+
Sbjct: 77 VWSYVLSAPNTNSYIAMGFSEKGKMVGSTAIVGWVSNDGTATMKKYFLGGQSPNQVLPDE 136
Query: 183 GSLSIVSNSTTVISQSSR 236
G+L +V+ +++V++++SR
Sbjct: 137 GNLQLVNFTSSVVAENSR 154
>ref|XP_003637246.1| Ferric-chelate reductase [Medicago truncatula]
gi|355503181|gb|AES84384.1| Ferric-chelate reductase
[Medicago truncatula]
Length = 308
Score = 105 bits (263), Expect = 5e-21
Identities = 51/79 (64%), Positives = 64/79 (81%), Gaps = 1/79 (1%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNG-SGVIKQYYLGATNPNQVIPD 179
IW+F+LSAPN NSYI+IGFS NG MVGSSA+VGW+ NG SG +KQY L PNQV+P+
Sbjct: 10 IWSFILSAPNQNSYISIGFSPNGGMVGSSAIVGWISSNGASGGMKQYSLSGYAPNQVVPN 69
Query: 180 QGSLSIVSNSTTVISQSSR 236
+G+L I++NST + SQSSR
Sbjct: 70 RGNLPIINNSTMITSQSSR 88
>gb|EXB40467.1| Putative ferric-chelate reductase 1 [Morus notabilis]
Length = 365
Score = 103 bits (257), Expect = 2e-20
Identities = 50/79 (63%), Positives = 67/79 (84%), Gaps = 1/79 (1%)
Frame = +3
Query: 3 IWNFVLSAP-NTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPD 179
+W+FVLSAP + NSY+AIGFS++G MVGSSA+VGW+ +G+GVIKQYYLG T+ N+V PD
Sbjct: 67 VWSFVLSAPGDVNSYVAIGFSSDGGMVGSSAVVGWIS-DGAGVIKQYYLGGTSSNRVEPD 125
Query: 180 QGSLSIVSNSTTVISQSSR 236
QG+L V NS +++SQS+R
Sbjct: 126 QGNLIFVQNSPSIVSQSNR 144
>ref|XP_004246246.1| PREDICTED: ferric-chelate reductase 1-like isoform 2 [Solanum
lycopersicum]
Length = 306
Score = 99.8 bits (247), Expect = 4e-19
Identities = 41/78 (52%), Positives = 66/78 (84%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W+F+LSAPN+NS+I +GFS +GKMVGSSA+VGW+ +GS +K+YYLG + QV+PD+
Sbjct: 64 VWSFLLSAPNSNSFIGMGFSKDGKMVGSSAIVGWISNDGSSTMKRYYLGGQSSAQVVPDE 123
Query: 183 GSLSIVSNSTTVISQSSR 236
G+L +V+ ++++I+++SR
Sbjct: 124 GNLQLVNMTSSIIAENSR 141
>ref|XP_004246245.1| PREDICTED: ferric-chelate reductase 1-like isoform 1 [Solanum
lycopersicum]
Length = 362
Score = 99.8 bits (247), Expect = 4e-19
Identities = 41/78 (52%), Positives = 66/78 (84%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W+F+LSAPN+NS+I +GFS +GKMVGSSA+VGW+ +GS +K+YYLG + QV+PD+
Sbjct: 64 VWSFLLSAPNSNSFIGMGFSKDGKMVGSSAIVGWISNDGSSTMKRYYLGGQSSAQVVPDE 123
Query: 183 GSLSIVSNSTTVISQSSR 236
G+L +V+ ++++I+++SR
Sbjct: 124 GNLQLVNMTSSIIAENSR 141
>ref|XP_003635609.1| PREDICTED: uncharacterized protein LOC100853065, partial [Vitis
vinifera]
Length = 287
Score = 99.8 bits (247), Expect = 4e-19
Identities = 47/78 (60%), Positives = 62/78 (79%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W+FVLSAP+TN+YIAIGFS++G MVGSSA+VGWV NG IKQYYLG T + V P++
Sbjct: 70 LWSFVLSAPDTNAYIAIGFSSDGSMVGSSAIVGWVGSNGG--IKQYYLGGTQSSSVEPNK 127
Query: 183 GSLSIVSNSTTVISQSSR 236
GSL ++ N++ +SQS R
Sbjct: 128 GSLQVLGNTSAALSQSQR 145
>ref|XP_002270178.2| PREDICTED: putative ferric-chelate reductase 1-like [Vitis
vinifera]
Length = 357
Score = 99.8 bits (247), Expect = 4e-19
Identities = 47/78 (60%), Positives = 62/78 (79%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W+FVLSAP+TN+YIAIGFS++G MVGSSA+VGWV NG IKQYYLG T + V P++
Sbjct: 61 LWSFVLSAPDTNAYIAIGFSSDGSMVGSSAIVGWVGSNGG--IKQYYLGGTQSSSVEPNK 118
Query: 183 GSLSIVSNSTTVISQSSR 236
GSL ++ N++ +SQS R
Sbjct: 119 GSLQVLGNTSAALSQSQR 136
>emb|CBI38284.3| unnamed protein product [Vitis vinifera]
Length = 373
Score = 99.8 bits (247), Expect = 4e-19
Identities = 47/78 (60%), Positives = 62/78 (79%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W+FVLSAP+TN+YIAIGFS++G MVGSSA+VGWV NG IKQYYLG T + V P++
Sbjct: 16 LWSFVLSAPDTNAYIAIGFSSDGSMVGSSAIVGWVGSNGG--IKQYYLGGTQSSSVEPNK 73
Query: 183 GSLSIVSNSTTVISQSSR 236
GSL ++ N++ +SQS R
Sbjct: 74 GSLQVLGNTSAALSQSQR 91
>ref|XP_006469476.1| PREDICTED: uncharacterized protein LOC102623024 [Citrus sinensis]
Length = 368
Score = 98.6 bits (244), Expect = 8e-19
Identities = 46/78 (58%), Positives = 61/78 (78%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W+FVLSAP+ NSYIA+GFS +G MVGSSA+VGWV +G+ I+QY L P+QV+ +Q
Sbjct: 71 VWSFVLSAPDNNSYIAMGFSPSGGMVGSSAVVGWVSADGTPTIRQYALRGQKPSQVVVNQ 130
Query: 183 GSLSIVSNSTTVISQSSR 236
GSL I NS+ ++SQSSR
Sbjct: 131 GSLQITGNSSMILSQSSR 148
>ref|XP_006447897.1| hypothetical protein CICLE_v10015681mg [Citrus clementina]
gi|557550508|gb|ESR61137.1| hypothetical protein
CICLE_v10015681mg [Citrus clementina]
Length = 368
Score = 98.6 bits (244), Expect = 8e-19
Identities = 46/78 (58%), Positives = 61/78 (78%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W+FVLSAP+ NSYIA+GFS +G MVGSSA+VGWV +G+ I+QY L P+QV+ +Q
Sbjct: 71 VWSFVLSAPDNNSYIAMGFSPSGGMVGSSAVVGWVSADGTPTIRQYALRGQKPSQVVVNQ 130
Query: 183 GSLSIVSNSTTVISQSSR 236
GSL I NS+ ++SQSSR
Sbjct: 131 GSLQITGNSSMILSQSSR 148
>ref|XP_006344352.1| PREDICTED: uncharacterized protein LOC102596514 [Solanum tuberosum]
Length = 362
Score = 98.2 bits (243), Expect = 1e-18
Identities = 41/77 (53%), Positives = 65/77 (84%)
Frame = +3
Query: 3 IWNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPNGSGVIKQYYLGATNPNQVIPDQ 182
+W+FV+SAPN+NS+I +GFS +GKMVGSSA+VGWV +GS +K+Y+LG + +V+PDQ
Sbjct: 64 VWSFVISAPNSNSFIGMGFSKDGKMVGSSAIVGWVSNDGSSTMKRYFLGGESSAEVVPDQ 123
Query: 183 GSLSIVSNSTTVISQSS 233
G+L +V+ ++++I+Q+S
Sbjct: 124 GNLQLVNMTSSIIAQNS 140
>ref|NP_566313.2| Cytochrome b561/ferric reductase transmembrane with DOMON related
domain [Arabidopsis thaliana]
gi|110736322|dbj|BAF00131.1| hypothetical protein
[Arabidopsis thaliana] gi|332641046|gb|AEE74567.1|
Cytochrome b561/ferric reductase transmembrane with
DOMON related domain [Arabidopsis thaliana]
Length = 369
Score = 96.7 bits (239), Expect = 3e-18
Identities = 44/78 (56%), Positives = 62/78 (79%), Gaps = 1/78 (1%)
Frame = +3
Query: 6 WNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPN-GSGVIKQYYLGATNPNQVIPDQ 182
W+F+LSAP+++++I IGFSTNG+M+GSSA+VGW+P + GSG +K Y LG +P +V PDQ
Sbjct: 69 WSFILSAPDSSAFIGIGFSTNGQMIGSSAIVGWIPSDGGSGTVKPYLLGGKSPGEVNPDQ 128
Query: 183 GSLSIVSNSTTVISQSSR 236
G L+IV+ S + S SSR
Sbjct: 129 GDLTIVNGSLKIESVSSR 146
>ref|XP_002884658.1| predicted protein [Arabidopsis lyrata subsp. lyrata]
gi|297330498|gb|EFH60917.1| predicted protein
[Arabidopsis lyrata subsp. lyrata]
Length = 467
Score = 96.7 bits (239), Expect = 3e-18
Identities = 44/78 (56%), Positives = 62/78 (79%), Gaps = 1/78 (1%)
Frame = +3
Query: 6 WNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPN-GSGVIKQYYLGATNPNQVIPDQ 182
W+F+LSAP+++++I IGFSTNG+M+GSSA+VGW+P + GSG +K Y LG +P +V PDQ
Sbjct: 70 WSFILSAPDSSAFIGIGFSTNGQMIGSSAIVGWIPSDGGSGTVKPYLLGGKSPGEVNPDQ 129
Query: 183 GSLSIVSNSTTVISQSSR 236
G L+IV+ S + S SSR
Sbjct: 130 GDLTIVNGSLKIESVSSR 147
>gb|AAF13075.1|AC009176_2 unknown protein [Arabidopsis thaliana]
Length = 457
Score = 96.7 bits (239), Expect = 3e-18
Identities = 44/78 (56%), Positives = 62/78 (79%), Gaps = 1/78 (1%)
Frame = +3
Query: 6 WNFVLSAPNTNSYIAIGFSTNGKMVGSSAMVGWVPPN-GSGVIKQYYLGATNPNQVIPDQ 182
W+F+LSAP+++++I IGFSTNG+M+GSSA+VGW+P + GSG +K Y LG +P +V PDQ
Sbjct: 69 WSFILSAPDSSAFIGIGFSTNGQMIGSSAIVGWIPSDGGSGTVKPYLLGGKSPGEVNPDQ 128
Query: 183 GSLSIVSNSTTVISQSSR 236
G L+IV+ S + S SSR
Sbjct: 129 GDLTIVNGSLKIESVSSR 146