BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Achyranthes23_contig00002614
         (2639 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                 936   0.0  
ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform ...   933   0.0  
ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citr...   932   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]               930   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]       924   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]                913   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...   913   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]             912   0.0  
gb|EOY12189.1| DNA topoisomerase I alpha isoform 1 [Theobroma ca...   910   0.0  
ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis...   904   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                  900   0.0  
ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis v...   900   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]               898   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                  896   0.0  
ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinife...   895   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]             893   0.0  
dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]                  887   0.0  
dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]                 879   0.0  
dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]              877   0.0  
ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...   877   0.0  

>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score =  936 bits (2418), Expect = 0.0
 Identities = 478/744 (64%), Positives = 554/744 (74%), Gaps = 8/744 (1%)
 Frame = -3

Query: 2265 KPLSARMDKGRPMAGASQTQKMKAMNVKPAADDSDDEKPLSIKLN-KSNSGVSSVKYYDS 2089
            KPLS R          +Q  K  +   KP  +DSDDEKPLS +   KS  G S+ K YDS
Sbjct: 170  KPLSLRHSASSSKGNTNQVSKEGS---KPENEDSDDEKPLSSRFPLKSGVGESTSKAYDS 226

Query: 2088 DEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEA-SSGQSSVKKAKLSDASSSGKAK 1912
            D+ KPLA KL  NG+  R+    K    S KRP  +  SS Q SVKK KLS  ++    K
Sbjct: 227  DDDKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKK 286

Query: 1911 QIPVKGAAK---DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1741
            Q  VK   K   DDDDH+PISQR+                                    
Sbjct: 287  QASVKPEPKAEDDDDDHLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMK 346

Query: 1740 XXXXXXXKELP-NSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATM 1564
                    ++P +SGEG+KW  L HNGVIFPPPY+ HGIKMLY GKPVDLTPEQEEVATM
Sbjct: 347  NSKYSKSSKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATM 406

Query: 1563 YAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXX 1384
            +AVML+TDY+ K +F ENFFGDWKK+LGKNHVIQ+L  CDF+PIYEWH            
Sbjct: 407  FAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTT 466

Query: 1383 XXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRD 1204
                           KYMWA +DG KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P D
Sbjct: 467  EEKKALKEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCD 526

Query: 1203 ITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQS 1024
            ITINIGKDAPIPECP+PG+RWKEVRHDNTVTWLA+WNDPINP+EFKYVFLAASS+LKG S
Sbjct: 527  ITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLS 586

Query: 1023 DKEKYEKARKLKDYIEGIRSAYTKDFTSKDLTRQQIAVATYLIDRLALRAGNEKDEEEAD 844
            DKEKYEKAR LKDYI+GIR+AYTKDF SKD T++QIAVATYLID+LALRAGNEKD++EAD
Sbjct: 587  DKEKYEKARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEAD 646

Query: 843  TVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLF 664
            TVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + E +  V+KA+++FR GK+G+ DLF
Sbjct: 647  TVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLF 706

Query: 663  DMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEV 484
            D+LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML++    G+V EK+ +YQHANKEV
Sbjct: 707  DLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEV 766

Query: 483  AIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLL--KDSSGKQKR 310
            AIICNHQRTVSKSHSAQM RL  +I+E KA + +L+ DL+R +KGKP L  K++ GK KR
Sbjct: 767  AIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKR 826

Query: 309  NLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPI 130
            NL+PE++EKKI  T  +IEK ERDK++KEDLK +ALGTSKINYLDPRITVAWCKR+EVPI
Sbjct: 827  NLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 886

Query: 129  EKMFNKSLLAKFSWAMDCDPSFRF 58
            EK+FNKSLLAKF+WAMD DPSFRF
Sbjct: 887  EKIFNKSLLAKFTWAMDVDPSFRF 910


>ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform X1 [Citrus sinensis]
            gi|568842074|ref|XP_006474978.1| PREDICTED: DNA
            topoisomerase 1-like isoform X2 [Citrus sinensis]
            gi|568842076|ref|XP_006474979.1| PREDICTED: DNA
            topoisomerase 1-like isoform X3 [Citrus sinensis]
            gi|568842078|ref|XP_006474980.1| PREDICTED: DNA
            topoisomerase 1-like isoform X4 [Citrus sinensis]
          Length = 902

 Score =  933 bits (2411), Expect = 0.0
 Identities = 508/834 (60%), Positives = 577/834 (69%), Gaps = 19/834 (2%)
 Frame = -3

Query: 2502 TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVLSQRG 2323
            T+ A ++  KS     VK   R+PV      S +             PL  R     Q  
Sbjct: 82   TSSAKASPSKSPMRSPVKSPVRSPVKSPVANSKES-----------SPLDDRLKQSPQHN 130

Query: 2322 NSTVANVE-------VKPXXXXXXXDKPLSARMDKGRPM-----AGASQTQK-MKAMNVK 2182
               V   E       +K        DKPLSAR+ KG         GAS+    +  +NVK
Sbjct: 131  ALAVVKKEEIKDGNGLKSDDNDSEDDKPLSARL-KGNSKNVNQGIGASKADAAISEVNVK 189

Query: 2181 PAADDSDDEKPLSIKLNKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSS 2002
               +DSDDE PLS +  KSN+G S  K  DSDE KPLASK+ QNG+  R T   K     
Sbjct: 190  TDPEDSDDEVPLSSRFPKSNAGTSGAKPIDSDEKKPLASKVQQNGSTSRET-QQKSSSVP 248

Query: 2001 VKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK-DDDDHIPISQRMXXXXXXX 1828
            VKRP  +ASS G SS KK K+SD S   K KQ+ VK   K DDDDHIPISQRM       
Sbjct: 249  VKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKKADDDDHIPISQRMKNSAPSV 308

Query: 1827 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKE--LPNSGEGQK-WTTLVHNGVI 1657
                                                    LP SG+GQK WTTLVHNGVI
Sbjct: 309  KKSVTNTAKATKSVSSSSNKINKKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTLVHNGVI 368

Query: 1656 FPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGK 1477
            FPPPY  HG+KMLY GK V+LTPEQEEVATM+AVML+TDY++K KF ENF+ DW+KLLGK
Sbjct: 369  FPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLLGK 428

Query: 1476 NHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKV 1297
            NHVIQ+L  CDF PIY+WH                           KYMWAI+DGVKEKV
Sbjct: 429  NHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEKLKQEEKYMWAIVDGVKEKV 488

Query: 1296 GNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNT 1117
            GNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIGKD PIPECPIPG+ WKEV+HDNT
Sbjct: 489  GNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVPIPECPIPGESWKEVKHDNT 548

Query: 1116 VTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTSK 937
            VTWLA+WNDPINP+EFKYVFLAASSSLKGQSDKEKYEKARKLKDYI  IR+AYTKDF S+
Sbjct: 549  VTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHSIRAAYTKDFVSR 608

Query: 936  DLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDS 757
            D TR+QIAVATYLID+LALRAGNEKD++EADTVGCCTLKV NV+ IPPN L+FDFLGKDS
Sbjct: 609  DGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLKFDFLGKDS 668

Query: 756  IKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNA 577
            I+Y    E +  VYKA+ +F+ GKK NDDLFD LDT+KLNAHLKELMPGLTAKVFRT+NA
Sbjct: 669  IQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNA 728

Query: 576  SFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAK 397
            S TLD ML KG G G+V  KI +YQ ANKEVAIICNHQRTVSK+HSAQM RL  +I++ K
Sbjct: 729  SITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLK 788

Query: 396  AELNDLEKDLARARKGK-PLLKDSSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKED 220
              L DL  DL RA+KGK PL+KDS GK+KRNL+PEA+E+K+  T  +IEK ERD ++KED
Sbjct: 789  GVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKED 848

Query: 219  LKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 58
            LK +ALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKF+WAMD DP FRF
Sbjct: 849  LKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPEFRF 902


>ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|567920950|ref|XP_006452481.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555705|gb|ESR65719.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555707|gb|ESR65721.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 902

 Score =  932 bits (2410), Expect = 0.0
 Identities = 508/834 (60%), Positives = 578/834 (69%), Gaps = 19/834 (2%)
 Frame = -3

Query: 2502 TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVLSQRG 2323
            T+ A ++  KS     VK   R+PV      S +             PL  R   L Q  
Sbjct: 82   TSSAKASPLKSPMRSPVKSPVRSPVKSPVANSKES-----------SPLDDRLKQLPQHN 130

Query: 2322 NSTVANVE-------VKPXXXXXXXDKPLSARMDKGRPM-----AGASQTQK-MKAMNVK 2182
               V   E       +K        DKPLSAR+ KG         GAS+    +  +NVK
Sbjct: 131  ALAVVKKEEIKDGNGLKSDDNDSEDDKPLSARL-KGNTKNVNQGIGASKADAAISEVNVK 189

Query: 2181 PAADDSDDEKPLSIKLNKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSS 2002
               +DSDDE PLS +  KSN+G S  K  DSDE KPLASK+ QNG+  R T   K     
Sbjct: 190  TDPEDSDDEVPLSSRFPKSNAGTSGAKPIDSDEKKPLASKVQQNGSTSRET-QQKSSSVP 248

Query: 2001 VKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK-DDDDHIPISQRMXXXXXXX 1828
            VKRP  +ASS G SS KK K+SD S   K KQ+ VK   K DDDDHIPISQRM       
Sbjct: 249  VKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKKADDDDHIPISQRMKNSAPSV 308

Query: 1827 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKE--LPNSGEGQK-WTTLVHNGVI 1657
                                                    LP SG+GQK WTTLVHNGVI
Sbjct: 309  KKSVTNTAKATKSVSSSSKKINKKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTLVHNGVI 368

Query: 1656 FPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGK 1477
            FPPPY  HG+KMLY GK V+LTPEQEEVATM+AVML+TDY++K KF ENF+ DW+KLLGK
Sbjct: 369  FPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLLGK 428

Query: 1476 NHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKV 1297
            NHVIQ+L  CDF PIY+WH                           KYMWAI+DGVKEKV
Sbjct: 429  NHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEKLKQEEKYMWAIVDGVKEKV 488

Query: 1296 GNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNT 1117
            GNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIGKD PIPECPIPG+ WKEV+HDNT
Sbjct: 489  GNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVPIPECPIPGESWKEVKHDNT 548

Query: 1116 VTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTSK 937
            VTWLA+WNDPINP+EFKYVFLAASSSLKGQSD+EKYEKARKLKDYI  IR+AYTKDF S+
Sbjct: 549  VTWLAFWNDPINPKEFKYVFLAASSSLKGQSDREKYEKARKLKDYIHSIRAAYTKDFVSR 608

Query: 936  DLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDS 757
            D TR+QIAVATYLID+LALRAGNEKD++EADTVGCCTLKV NV+ IPPN L+FDFLGKDS
Sbjct: 609  DGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLKFDFLGKDS 668

Query: 756  IKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNA 577
            I+Y    E +  VYKA+ +F+ GKK NDDLFD LDT+KLNAHLKELMPGLTAKVFRT+NA
Sbjct: 669  IQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNA 728

Query: 576  SFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAK 397
            S TLD ML KG G G+V  KI +YQ ANKEVAIICNHQRTVSK+HSAQM RL  +I++ K
Sbjct: 729  SITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLK 788

Query: 396  AELNDLEKDLARARKGK-PLLKDSSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKED 220
              L DL  DL RA+KGK PL+KDS GK+KRNL+PEA+E+K+  T  +IEK ERD ++KED
Sbjct: 789  GVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKED 848

Query: 219  LKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 58
            LK +ALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKF+WAMD DP FRF
Sbjct: 849  LKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPEFRF 902


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score =  930 bits (2403), Expect = 0.0
 Identities = 484/755 (64%), Positives = 555/755 (73%), Gaps = 19/755 (2%)
 Frame = -3

Query: 2265 KPLSARMDKGRPMAGASQTQKMKAMNVKPAA------------DDSDDEKPLSIKLN-KS 2125
            KPLSAR+  G    G+S       +N  PA+            DDSDDE PLS K   K+
Sbjct: 144  KPLSARLFTGLTK-GSSNNANKGLINSSPASLPVPKPEINRYSDDSDDEIPLSSKFRLKA 202

Query: 2124 NSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEA-SSGQSSVKKA 1948
            N+G S+VK Y+SD++K L S   QNG+I R + S   +    KRP  E  SS QSSVKK 
Sbjct: 203  NAGTSTVKSYESDDNKTLVSNFQQNGSINRGSKSSIKVN---KRPLGEVKSSVQSSVKKP 259

Query: 1947 KLSDASSSGKAKQIPVKGAAK---DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXX 1777
            KLSDAS+    KQ   K   K    DDDH+PISQRM                        
Sbjct: 260  KLSDASTPVNNKQASKKAEPKADDSDDDHVPISQRMKKSATSGNKSSTAKQKVTKVVSSS 319

Query: 1776 XXXXXXXXXXXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKP 1603
                                    P+SGEG+KW TLVHNGVIFPPPY+ HG+KMLY GKP
Sbjct: 320  MKKASKKFKKVVKKSKYSKSSKVPPSSGEGKKWNTLVHNGVIFPPPYKPHGVKMLYKGKP 379

Query: 1602 VDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEW 1423
            VDLTPEQEEVATM+AVML+TDY+ K KF ENF  DW+K+LGKNHVIQ+L  CDFTPIYEW
Sbjct: 380  VDLTPEQEEVATMFAVMLDTDYMTKSKFKENFMDDWRKILGKNHVIQNLEDCDFTPIYEW 439

Query: 1422 HLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHP 1243
            H R                         KYMWAI++GVKEKVGNFRVEPP LFRGRGEHP
Sbjct: 440  HQREKEKKKKMTAEEKKVLKEERLKQEEKYMWAIVNGVKEKVGNFRVEPPSLFRGRGEHP 499

Query: 1242 KMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKY 1063
            KMGKLKK I P DITINIGKDAPIPECPIPG+ WKE+RHDNTVTWLA+WNDPI PREFKY
Sbjct: 500  KMGKLKKCIRPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAFWNDPIKPREFKY 559

Query: 1062 VFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTSKDLTRQQIAVATYLIDRLA 883
            VFLAASSSLKGQSDKEKYEKAR LKD+I+GIR+AYTKDF SKD+T++QIAVATYLID+LA
Sbjct: 560  VFLAASSSLKGQSDKEKYEKARLLKDFIQGIRAAYTKDFASKDITKRQIAVATYLIDKLA 619

Query: 882  LRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVE 703
            LRAGNEKD++EADTVGCCTLKVENV+P PP+IL+FDFLGKDSI+Y  + E +  VYKA++
Sbjct: 620  LRAGNEKDDDEADTVGCCTLKVENVEPKPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQ 679

Query: 702  RFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVL 523
            +FR GK+G DDLFD LDTSKLNAHLK LMPGLTAKVFRT+NAS TLD+ML++    G V 
Sbjct: 680  QFRTGKRGGDDLFDKLDTSKLNAHLKGLMPGLTAKVFRTYNASITLDEMLSRETKGGNVA 739

Query: 522  EKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKP 343
            EKI +YQHANKEVAIICNHQRTVSKSH AQM RL  +IDE K  L+ L+ DLARA+KGKP
Sbjct: 740  EKIVVYQHANKEVAIICNHQRTVSKSHPAQMTRLNGKIDELKGILDGLQTDLARAKKGKP 799

Query: 342  LLKDSSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRIT 163
             L+D+ GK KRNL+PEA+E+KI  T  +IEK ERDK++KE LK IALGTSKI+YLDPRIT
Sbjct: 800  PLEDADGKPKRNLTPEALERKIGQTNAKIEKMERDKETKEGLKTIALGTSKISYLDPRIT 859

Query: 162  VAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 58
            VAWCKR+EVPIEK+FNKSLLAKF+W+MD DPSFRF
Sbjct: 860  VAWCKRHEVPIEKVFNKSLLAKFAWSMDVDPSFRF 894


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score =  924 bits (2389), Expect = 0.0
 Identities = 502/867 (57%), Positives = 589/867 (67%), Gaps = 53/867 (6%)
 Frame = -3

Query: 2499 NGASSANDK-----SKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVL 2335
            NG SS+  K     S K   VK    +P   K   S  +           KP ++  S  
Sbjct: 62   NGESSSAQKGRIQPSAKTPPVKSPLSSP---KASNSSAKASPITSPGANSKPSASATSTA 118

Query: 2334 SQRGN--STVANVEVKPXXXXXXXD---------KPLSARM----DKGRPMAGASQTQKM 2200
             Q+ +  S+ A +E KP       +         KPLSAR      KG+      +    
Sbjct: 119  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 178

Query: 2199 KAMN--VKPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNT 2029
             ++   V   ++DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ 
Sbjct: 179  CSIRRPVIEESEDSEDEKPLSCRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDG 238

Query: 2028 PSMKVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK----------- 1885
            P  K    S KRP  EA S  QSSVKK KLS   +S   KQ  VK   K           
Sbjct: 239  PMNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 298

Query: 1884 ---------------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1750
                           DDDD++PISQR+                                 
Sbjct: 299  QRGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNKNSK 358

Query: 1749 XXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEE 1576
                           P SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEE
Sbjct: 359  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEE 418

Query: 1575 VATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXX 1396
            VATM+AVML+TDY+ K  F ENFF DWKK+LGKNH+IQ+L  CDF PIYEWH +      
Sbjct: 419  VATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKK 478

Query: 1395 XXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1216
                               KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI
Sbjct: 479  QMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 538

Query: 1215 YPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSL 1036
             PRDITINIGKDAPIPECPIPG+RWKEVR+ NTVTWLAYWNDPIN +EFKYVFLAASS+L
Sbjct: 539  RPRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTL 598

Query: 1035 KGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKD 859
            KGQSDKEKYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD
Sbjct: 599  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 658

Query: 858  EEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKG 679
            ++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + + +P V+KA+++FR GK+G
Sbjct: 659  DDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 718

Query: 678  NDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQH 499
            ++DLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    GEV E + +YQH
Sbjct: 719  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVVYQH 778

Query: 498  ANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGK 319
            ANKEVAIICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K + GK
Sbjct: 779  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGADGK 838

Query: 318  QKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNE 139
             KRNL+PEA+E+KI  T  +IEK ERDK++KEDLK +ALGTSKINYLDPRITVAWCKR+E
Sbjct: 839  AKRNLNPEALERKITQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 898

Query: 138  VPIEKMFNKSLLAKFSWAMDCDPSFRF 58
            VPIEK+FNKSLLAKF+W+MD DPSFRF
Sbjct: 899  VPIEKIFNKSLLAKFAWSMDVDPSFRF 925


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score =  913 bits (2360), Expect = 0.0
 Identities = 494/869 (56%), Positives = 587/869 (67%), Gaps = 55/869 (6%)
 Frame = -3

Query: 2499 NGASSANDK-----SKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVL 2335
            NG SS+  K     S K   VK    +P   K   S  +           KP ++  S  
Sbjct: 62   NGESSSAQKGRIQPSAKTPPVKSPLSSP---KASNSSAKASPITSPGANSKPSASATSTA 118

Query: 2334 SQRGN--STVANVEVKPXXXXXXXD---------KPLSARM----DKGRPMAGASQTQKM 2200
             Q+ +  S+ A +E KP       +         KPLSAR      KG+      +    
Sbjct: 119  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 178

Query: 2199 KAMN--VKPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNT 2029
             ++   V   ++DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG++ R+ 
Sbjct: 179  CSIRRRVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSVSRDG 238

Query: 2028 PSMKVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK----------- 1885
            P  K    S KRP  E  S  QSSVKK KLS   +S   KQ  VK   +           
Sbjct: 239  PMNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIP 298

Query: 1884 -----------------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1756
                             +DDD++PI+QR+                               
Sbjct: 299  LSQRGKKSQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKN 358

Query: 1755 XXXXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQ 1582
                             P SGEGQKWTTLVHNGVIFPPPY  HG+KMLY  +P+ LTPEQ
Sbjct: 359  SKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQ 418

Query: 1581 EEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXX 1402
            EEVATM+AVML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +    
Sbjct: 419  EEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEK 478

Query: 1401 XXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK 1222
                                 KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK
Sbjct: 479  KKQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK 538

Query: 1221 RIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASS 1042
            RI PRDITINIGKDAPIPECPIPG+RWKEVR+DNTVTWLA+W DPIN +EFKYVFLAASS
Sbjct: 539  RIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASS 598

Query: 1041 SLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNE 865
            +LKGQSDKEKYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNE
Sbjct: 599  TLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNE 658

Query: 864  KDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGK 685
            KD++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + + +P V+KA+++FR GK
Sbjct: 659  KDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGK 718

Query: 684  KGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIY 505
            +G++DLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    GEV EK+ +Y
Sbjct: 719  EGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVY 778

Query: 504  QHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSS 325
            QHANKEVAIICNHQRTVSKSHSAQM RL  +IDE K  + +L+ DL+R +KGKP  K + 
Sbjct: 779  QHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSKGAD 838

Query: 324  GKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKR 145
            GK KRNL+PEA+E+K+     +IEK ERDK++KEDLK +ALGTSKINYLDPRITVAWCKR
Sbjct: 839  GKPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKR 898

Query: 144  NEVPIEKMFNKSLLAKFSWAMDCDPSFRF 58
            +EVPIEK+FNKSLLAKF+W+MD DPSFRF
Sbjct: 899  HEVPIEKIFNKSLLAKFAWSMDVDPSFRF 927


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score =  913 bits (2359), Expect = 0.0
 Identities = 494/860 (57%), Positives = 585/860 (68%), Gaps = 53/860 (6%)
 Frame = -3

Query: 2499 NGASSANDK-----SKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVL 2335
            NG +S+  K     S K   VK    +P   K   S  +           KP ++  S  
Sbjct: 63   NGENSSAQKGRIQPSAKTPPVKSPLSSP---KASNSSAKASPITSAGANSKPSASATSTA 119

Query: 2334 SQRGN--STVANVEVKPXXXXXXXD---------KPLSARM----DKGRPMAGASQTQKM 2200
             Q+ +  S+ A +E KP       +         KPLSAR      KG+      +    
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 179

Query: 2199 KAMN--VKPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNT 2029
             ++   V   ++DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+  NG+  R++
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDS 239

Query: 2028 PSMKVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK----------- 1885
            P  K    S KRP  E  S  QSS+KK KLS   +S   KQ  VK   K           
Sbjct: 240  PMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 1884 ---------------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1750
                           +DDD++PISQR+                                 
Sbjct: 300  QRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 1749 XXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEE 1576
                           P SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEE 419

Query: 1575 VATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXX 1396
            VATM+AVML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +      
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1395 XXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1216
                               KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI
Sbjct: 480  QMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 539

Query: 1215 YPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSL 1036
             PRDITINIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDPIN +EFKYVFLAASS+L
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTL 599

Query: 1035 KGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKD 859
            KGQSDKEKYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 858  EEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKG 679
            ++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + + +P V+KA+++FR GK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 678  NDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQH 499
            ++DLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    GEV EK+ +YQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQH 779

Query: 498  ANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGK 319
            ANKEVAIICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKPL K + GK
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGK 839

Query: 318  QKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNE 139
             KRNL+PEA+E+KI  T  +IEK ERDK++KEDLK +ALGTSKINYLDPRITVAWCKR+E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 899

Query: 138  VPIEKMFNKSLLAKFSWAMD 79
            VPIEK+FNKSLLAKF+WAM+
Sbjct: 900  VPIEKIFNKSLLAKFAWAMN 919


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score =  912 bits (2357), Expect = 0.0
 Identities = 494/860 (57%), Positives = 584/860 (67%), Gaps = 53/860 (6%)
 Frame = -3

Query: 2499 NGASSANDK-----SKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVL 2335
            NG +S+  K     S K   VK    +P   K   S  +           KP ++  S  
Sbjct: 63   NGENSSAQKGRIQPSAKTPPVKSPLSSP---KASNSSAKASPITSPGANSKPSASATSTA 119

Query: 2334 SQRGN--STVANVEVKPXXXXXXXD---------KPLSARM----DKGRPMAGASQTQKM 2200
             Q+ +  S+ A +E KP       +         KPLSAR      KG+      +    
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 179

Query: 2199 KAMN--VKPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNT 2029
             ++   V   ++DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+  NG+  R++
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDS 239

Query: 2028 PSMKVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK----------- 1885
            P  K    S KRP  E  S  QSS+KK KLS   +S   KQ  VK   K           
Sbjct: 240  PMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 1884 ---------------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1750
                           +DDD++PISQR+                                 
Sbjct: 300  QRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 1749 XXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEE 1576
                           P SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEE 419

Query: 1575 VATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXX 1396
            VATM+AVML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +      
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1395 XXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1216
                               KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI
Sbjct: 480  QMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 539

Query: 1215 YPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSL 1036
             PRDITINIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDPIN +EFKYVFLAASS+L
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTL 599

Query: 1035 KGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKD 859
            KGQSDKEKYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 858  EEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKG 679
            ++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + + +P V+KA+ +FR GK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSGKEG 719

Query: 678  NDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQH 499
            ++DLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    GEV EK+ +YQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQH 779

Query: 498  ANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGK 319
            ANKEVAIICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKPL K + GK
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGK 839

Query: 318  QKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNE 139
             KRNL+PEA+E+KI  T  +IEK ERDK++KEDLK +ALGTSKINYLDPRITVAWCKR+E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 899

Query: 138  VPIEKMFNKSLLAKFSWAMD 79
            VPIEK+FNKSLLAKF+WAM+
Sbjct: 900  VPIEKIFNKSLLAKFAWAMN 919


>gb|EOY12189.1| DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
            gi|508720293|gb|EOY12190.1| DNA topoisomerase I alpha
            isoform 1 [Theobroma cacao]
          Length = 904

 Score =  910 bits (2352), Expect = 0.0
 Identities = 467/748 (62%), Positives = 553/748 (73%), Gaps = 13/748 (1%)
 Frame = -3

Query: 2262 PLSARM-------DKGRPMAGASQTQKM-KAMNVKPAADDSDDEKPLSIKLN-KSNSGVS 2110
            PLSAR+       +KG   +  +Q++++     VK +A+D DDE PLS + N KSN+G S
Sbjct: 157  PLSARLKGISNQGNKGASTSAPAQSRRLVPKTEVKVSAEDPDDEAPLSARFNVKSNTGTS 216

Query: 2109 SVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEASSGQSSVKKAKLSDAS 1930
            S + +D DE KPLASK+ QNG+I +         S  +      SS  SS KK K SDA 
Sbjct: 217  SSRLHDCDEKKPLASKIQQNGSIMKGKQQNSSTLSGKRPLDKGNSSDHSSAKKPKTSDAP 276

Query: 1929 SSGKAKQIPVKGA-AKDDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1753
            ++ K KQ+ VK   A +DDDH+PI+QRM                                
Sbjct: 277  TTMKTKQVTVKAEKADEDDDHMPIAQRMKKSTASNSKLSSMKQKTTKVVSSSFKKINKKS 336

Query: 1752 XXXXXXXXXXXKEL--PNSGEGQK-WTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQ 1582
                            P+SG+GQK W+TLVHNGVIFP PY  HG+KMLY+G+PVDLTPEQ
Sbjct: 337  KKEMKSSKYIKSTKVPPSSGDGQKKWSTLVHNGVIFPSPYTPHGVKMLYDGRPVDLTPEQ 396

Query: 1581 EEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXX 1402
            EEVATM+AVM +TDY+ K +F +NF+ DW KLLGKNH I+DL +CDFTPIYEWHL+    
Sbjct: 397  EEVATMFAVMKDTDYMSKTQFKKNFWEDWSKLLGKNHTIKDLDRCDFTPIYEWHLQEKEK 456

Query: 1401 XXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK 1222
                                 K+MWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+
Sbjct: 457  KKQMSSEEKKALKEEKLKQEEKFMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKR 516

Query: 1221 RIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASS 1042
            RI P DITINIGKDAPIPECPIPG+RWK+++HDNTVTWLA+WNDPINP+EFKYVFLAASS
Sbjct: 517  RIRPSDITINIGKDAPIPECPIPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLAASS 576

Query: 1041 SLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTSKDLTRQQIAVATYLIDRLALRAGNEK 862
            SLKGQSDKEKYEKAR LKDYI+ IR+AYTKDFT+KD+ ++QIAVATYLID+LALRAGNEK
Sbjct: 577  SLKGQSDKEKYEKARMLKDYIKNIRAAYTKDFTTKDVMKRQIAVATYLIDKLALRAGNEK 636

Query: 861  DEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKK 682
            D++EADTVGCCTLKV NV+ IPPN L+FDFLGKDSI+Y    E +  VYKA+ +F+ GK 
Sbjct: 637  DDDEADTVGCCTLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKS 696

Query: 681  GNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQ 502
             +DDLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLD+ML K    G+V EK+ +YQ
Sbjct: 697  KSDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNKETKDGDVAEKVVVYQ 756

Query: 501  HANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSG 322
             ANKEVAIICNHQR++SKSHSAQM RL  +I E K  L +L+ DL RA+KGKP LKD+ G
Sbjct: 757  RANKEVAIICNHQRSISKSHSAQMSRLTEKITELKGVLKELKIDLDRAKKGKPPLKDADG 816

Query: 321  KQKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRN 142
            KQKRNL+P+AI+KKI  T  +IEK ERD Q+KEDLK +ALGTSKINYLDPRITVAWCKR+
Sbjct: 817  KQKRNLTPQAIQKKIDQTNAKIEKMERDMQTKEDLKTVALGTSKINYLDPRITVAWCKRH 876

Query: 141  EVPIEKMFNKSLLAKFSWAMDCDPSFRF 58
            EVPIEK+FNKSLLAKF+WAMD DP FRF
Sbjct: 877  EVPIEKIFNKSLLAKFAWAMDVDPDFRF 904


>ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis sativus]
            gi|449503189|ref|XP_004161878.1| PREDICTED: DNA
            topoisomerase 1-like [Cucumis sativus]
          Length = 889

 Score =  904 bits (2336), Expect = 0.0
 Identities = 477/746 (63%), Positives = 541/746 (72%), Gaps = 10/746 (1%)
 Frame = -3

Query: 2265 KPLSARMDKGRP-MAGASQTQKMKAMNVKPAADDSDDEKPLSIKLN-KSNSGVSSVKYYD 2092
            KPLS R+ KG P          +    VK +  DSDDE PLS K   K  SGV   K + 
Sbjct: 146  KPLSIRL-KGNPNQPNKGLVSTVPKNKVKKSLADSDDEVPLSSKFQMKHASGVLGSKQHG 204

Query: 2091 SDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEASS---GQSSVKKAKLSDASSSG 1921
             DE KPL  K+ QNG+  R+      + SS KRP     S    Q   KK KL+D+SS  
Sbjct: 205  FDEKKPLVPKVHQNGSTSRDKLQKPAVLSS-KRPLPNEDSHSPSQFPTKKPKLTDSSSPL 263

Query: 1920 KAKQIPVKGAAK--DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1747
             +K + +K   +  DDDD IPISQRM                                  
Sbjct: 264  NSKLVSLKAKQEVDDDDDDIPISQRMKKVSATVNKSSSSKPTISKVVSSSIKKTFKKSKK 323

Query: 1746 XXXXXXXXXKE--LPNSGEGQK-WTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEE 1576
                         LP++G+GQK WTTLVHNGVIFPPPYQ+HG+KMLY GKPVDLTP QEE
Sbjct: 324  PVKKSKYVKSTKLLPSAGDGQKKWTTLVHNGVIFPPPYQTHGVKMLYKGKPVDLTPPQEE 383

Query: 1575 VATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXX 1396
            VATM+AVM +TDY+ K KF ENF+ DW+KLLGKNHVIQ+L  CDFTPIY+W+        
Sbjct: 384  VATMFAVMKDTDYMLKPKFKENFWNDWRKLLGKNHVIQNLDDCDFTPIYDWYQMEKEKKK 443

Query: 1395 XXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1216
                               KYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI
Sbjct: 444  QMTTEEKKAVKEEKLKQEEKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRI 503

Query: 1215 YPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSL 1036
             P DITINIGK APIPECPIPG+RWKEVRHDNTVTWLA+WNDPIN +EFKYVFLAASSSL
Sbjct: 504  CPSDITINIGKGAPIPECPIPGERWKEVRHDNTVTWLAFWNDPINQKEFKYVFLAASSSL 563

Query: 1035 KGQSDKEKYEKARKLKDYIEGIRSAYTKDFTSKDLTRQQIAVATYLIDRLALRAGNEKDE 856
            KGQSDKEKYEKAR LKDYI+ IR+AYTKDFTSKD TR+QIAVATYLID+LALRAGNEKD+
Sbjct: 564  KGQSDKEKYEKARMLKDYIKNIRNAYTKDFTSKDPTRRQIAVATYLIDKLALRAGNEKDD 623

Query: 855  EEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGN 676
            +EADTVGCCTLKVENVK +PPN+LEF+FLGKDSI+Y    E +  V+KA+ +F+ GK G 
Sbjct: 624  DEADTVGCCTLKVENVKAVPPNLLEFNFLGKDSIRYENTVEVELPVFKAITQFQSGKSGT 683

Query: 675  DDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHA 496
            DDLFD LDTSKLNAHLK+LMPGLTAKVFRT+NAS TLDDML +G  +GEV EKI  YQHA
Sbjct: 684  DDLFDKLDTSKLNAHLKDLMPGLTAKVFRTYNASITLDDMLNRGTKNGEVSEKIVTYQHA 743

Query: 495  NKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQ 316
            NKEVAIICNHQRTVSKSH AQM RL  +I E +  L +L+ DL RA+KGKP LK S GKQ
Sbjct: 744  NKEVAIICNHQRTVSKSHGAQMTRLNEKISELRDILKELKIDLDRAKKGKPPLKGSDGKQ 803

Query: 315  KRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEV 136
            KRNL+PEA+EKKI  T  +IEK ERD ++KEDLK +ALGTSKINYLDPRITVAWCKR+EV
Sbjct: 804  KRNLTPEALEKKISQTNAKIEKIERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEV 863

Query: 135  PIEKMFNKSLLAKFSWAMDCDPSFRF 58
            PIEK+FNKSLLAKF+WAMD DP FRF
Sbjct: 864  PIEKIFNKSLLAKFAWAMDVDPDFRF 889


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score =  900 bits (2327), Expect = 0.0
 Identities = 477/800 (59%), Positives = 556/800 (69%), Gaps = 31/800 (3%)
 Frame = -3

Query: 2364 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2185
            KPL AR S  S +G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSKGKSNHANKE---------GGDSCSIR----RPVVEESE--------- 191

Query: 2184 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2008
                 DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2007 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 1885
             S KR   E  S  QSS+KK KLS   +S   KQ  VK   K                  
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 1884 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1729
                    +DDD+ PISQR+                                        
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1728 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1555
                    P SGEGQKWTTLVHNGV+FPPPY+ HG+KMLY  +P+ LTPEQEEVATM+A 
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAA 426

Query: 1554 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1375
            ML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEREKKKQMTTEEK 486

Query: 1374 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1195
                        KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI+PRDITI
Sbjct: 487  KALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIHPRDITI 546

Query: 1194 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1015
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDP+N +E KYVFLA SS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLKGQSDKE 606

Query: 1014 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 838
            KYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 837  GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 658
            GCCTLKVENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G++DLFD 
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 657  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 478
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 477  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 298
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K   G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 297  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 118
            EA+E+KI  T  +IEK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 117  NKSLLAKFSWAMDCDPSFRF 58
            NKSLLAKF+WAMD DPSFRF
Sbjct: 907  NKSLLAKFAWAMDVDPSFRF 926


>ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis vinifera]
          Length = 883

 Score =  900 bits (2325), Expect = 0.0
 Identities = 460/736 (62%), Positives = 533/736 (72%), Gaps = 11/736 (1%)
 Frame = -3

Query: 2232 PMAGASQTQKMKAMNVKPAADDSDDEKPLSIKLN-KSNSGVSSVKYYDSDEHKPLASKLL 2056
            P +   Q+QK K  N K  +DDS+DE PLS K   K+  G S  K  + DE KPL S L 
Sbjct: 149  PASSRPQSQKAKVNN-KNLSDDSEDEIPLSSKFRLKTGMGASLDKLDNFDEKKPLTSTLK 207

Query: 2055 QNGTIKRNTPSMKVLGSSVKRPSAEAS-SGQSSVKKAKLSDASSSGKAKQIPVKGAAKDD 1879
             NG  K++   +K      KRP  +A+ S  SS KK KL D S  GK KQ+ VK   KDD
Sbjct: 208  PNGISKKDDERVKSPKGQNKRPLGQANTSHHSSSKKPKLLDGSVKGKVKQVSVKAEQKDD 267

Query: 1878 DD--------HIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1723
            DD        + P  +R+                                          
Sbjct: 268  DDDDNDDDDEYTPTVKRLKKSVSSDNKKASKTKVIPSSRKKATKKAKKSKKLAKSSKYSK 327

Query: 1722 XKELP-NSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLE 1546
              ++P NSGEGQKWTTL HNGVIFPPPY+ HG+KMLYNG+PVDLTPEQEEVATM+AVM +
Sbjct: 328  STKVPPNSGEGQKWTTLEHNGVIFPPPYKPHGVKMLYNGRPVDLTPEQEEVATMFAVMKD 387

Query: 1545 TDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXX 1366
            TDY  K +F ENF  DW+  LGKNHVI+    CDFTPIYEWH +                
Sbjct: 388  TDYATKPRFIENFMNDWRVRLGKNHVIKKFELCDFTPIYEWHEKEKEKKKQMTTEEKKAL 447

Query: 1365 XXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIG 1186
                     KYMWA++DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIG
Sbjct: 448  KEEKLKQEDKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIG 507

Query: 1185 KDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYE 1006
            K+AP+PECPIPG+RWKEVRHDNTVTWLA+WNDPINP+EFKYVFLAASSSLKGQSDKEKYE
Sbjct: 508  KEAPVPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYE 567

Query: 1005 KARKLKDYIEGIRSAYTKDFTSKDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCT 826
            KAR LKDYI+ IR+ YTKDFT+KD  ++QIAVATYLID+LALRAGNEKD++EADTVGCCT
Sbjct: 568  KARLLKDYIQNIRATYTKDFTNKDTMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCT 627

Query: 825  LKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTS 646
            LKVENV  +PPN LEFDFLGKDSI+Y+   E +  VYKA+ +F+ GK G DDLFD LDTS
Sbjct: 628  LKVENVALVPPNKLEFDFLGKDSIRYFNTVEVELPVYKAIGQFKTGKSGGDDLFDKLDTS 687

Query: 645  KLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNH 466
            KLNAHLKELMPGLTAKVFRT+NAS TLD+ML + A  G+ +EKI IYQHANKEVAIICNH
Sbjct: 688  KLNAHLKELMPGLTAKVFRTYNASITLDEMLNREARGGDAMEKIVIYQHANKEVAIICNH 747

Query: 465  QRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSPEAIE 286
            QR+VSKSH  QM RL  ++ E +  L++L+ DLARA+KGKP LKDS GK K+N++PE +E
Sbjct: 748  QRSVSKSHDVQMSRLSEKMRELQGVLDELKTDLARAKKGKPPLKDSDGKPKKNMTPEVLE 807

Query: 285  KKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSL 106
            +KI  T  +IEK ERD ++KEDLK +ALGTSKINYLDPRI+VAWCKR EVPIEK+FNKSL
Sbjct: 808  RKIAQTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKSL 867

Query: 105  LAKFSWAMDCDPSFRF 58
            LAKF+WAMD DPSFRF
Sbjct: 868  LAKFAWAMDVDPSFRF 883


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score =  898 bits (2320), Expect = 0.0
 Identities = 468/773 (60%), Positives = 549/773 (71%), Gaps = 37/773 (4%)
 Frame = -3

Query: 2265 KPLSARMDKGRPMAGASQTQKMKAMN------VKPAADDSDDEKPLSIKL-NKSNSGVSS 2107
            KPL AR      M  ++   K    +      V   ++DS+DEKPLS +  +KS+ G S+
Sbjct: 154  KPLIARTSGCSSMGKSNHANKEGGDSCSIRRPVIEESEDSEDEKPLSRRFPSKSSLGEST 213

Query: 2106 VKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEASS-GQSSVKKAKLSDAS 1930
             K YDSDE KPLA+K+ QNG+     P  K    S KR   E  S  QSS+KK KLS   
Sbjct: 214  SKSYDSDEKKPLAAKVQQNGSASPEGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPI 273

Query: 1929 SSGKAKQIPVKGAAK--------------------------DDDDHIPISQRMXXXXXXX 1828
            +S   KQ  VK   K                          +DDDH PISQR+       
Sbjct: 274  TSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDHAPISQRIKKSPVSV 333

Query: 1827 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIF 1654
                                                     P SGEGQKWTTLVHNGV+F
Sbjct: 334  SKSSAPVKKASTVVSTSLKKVNKKSKKVIRKTAYTKSSKVPPGSGEGQKWTTLVHNGVMF 393

Query: 1653 PPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGKN 1474
            PPPY+ HG+KMLY  +P+ LTPEQEEVATM+AVML+TDY+ K +F ENFF DWKK+LGKN
Sbjct: 394  PPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKILGKN 453

Query: 1473 HVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVG 1294
            H IQ+L  CDF PIYEWH +                         KYMWAI+DGVKEKVG
Sbjct: 454  HTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVG 513

Query: 1293 NFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNTV 1114
            NFRVEPPGLFRGRGEHPK+GKLKKRI PRDITINIGKDAPIPECPIPG+RWKEVR+DNTV
Sbjct: 514  NFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTV 573

Query: 1113 TWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS-K 937
            TWLAYWNDP+N +E KYVFLAASS+LKGQS KEKYEKAR LKDYI GIR+AYTK FT+ K
Sbjct: 574  TWLAYWNDPVNIKECKYVFLAASSTLKGQSVKEKYEKARVLKDYIHGIRAAYTKGFTNNK 633

Query: 936  DLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDS 757
            D  ++QIAVATYLID+LALRAGNEKD++EADTVGCCTLKVENV+P+PPNIL+ DF+GKDS
Sbjct: 634  DPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDS 693

Query: 756  IKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNA 577
            I+Y  + + +P V+KA+++FR GK+G++DLFD LDTSKLNAHLKELMPGLTAKVFRT+NA
Sbjct: 694  IRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNA 753

Query: 576  SFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAK 397
            S TLDDML+K    G++ EK+A+YQHANKEVAIICNHQRTVSKSHSAQM RL  +IDE K
Sbjct: 754  SITLDDMLSKETKGGKIAEKVAVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELK 813

Query: 396  AELNDLEKDLARARKGKPLLKDSSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDL 217
              L +L+ DL+RA+KGKP  KD+ G+ KRNL+PE++E+KI  T  +IEK ERDK++KEDL
Sbjct: 814  TALEELKTDLSRAKKGKPPSKDADGEPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDL 873

Query: 216  KEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 58
            K +AL TSKI+YLDPRITVAWCKR EVPIEKMFNKSLLAKF+WAMD DPSFRF
Sbjct: 874  KAVALSTSKISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score =  896 bits (2315), Expect = 0.0
 Identities = 481/846 (56%), Positives = 567/846 (67%), Gaps = 31/846 (3%)
 Frame = -3

Query: 2502 TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVLSQRG 2323
            T+ A   N        ++ +   P A     S+            +KPL AR S  S +G
Sbjct: 116  TSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESS--------DDEKPLIARTSGCSSKG 167

Query: 2322 NSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNVKPAADDSDDEKPLS 2143
             S  AN E              S R    RP+   S+              DS+DEKPLS
Sbjct: 168  KSNHANKE---------GGDSCSIR----RPVIEESE--------------DSEDEKPLS 200

Query: 2142 IKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEASS-G 1969
             +  +KS+ G S+ K +DSDE KPLA+K+ QNG+  R+ P  K    S KR   E  S  
Sbjct: 201  RRFPSKSSLGESTSKSHDSDEKKPLAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLN 260

Query: 1968 QSSVKKAKLSDASSSGKAKQIPVKGAAK--------------------------DDDDHI 1867
            QSS+KK KLS   +S   KQ  VK   K                          +DDD+ 
Sbjct: 261  QSSLKKPKLSSTITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNA 320

Query: 1866 PISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEL--PNSGEG 1693
            PISQR+                                                P SGEG
Sbjct: 321  PISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEG 380

Query: 1692 QKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNE 1513
            QKWTTLVHNGV+FPPPY+ HG+KMLY  +P+ LTPEQEEVATM+A ML+TDY+ K +F E
Sbjct: 381  QKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAAMLDTDYMNKPRFKE 440

Query: 1512 NFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKY 1333
            NFF DWKK+LGKNH IQ+L  CDF PIYEWH +                         KY
Sbjct: 441  NFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEERLQLEEKY 500

Query: 1332 MWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIP 1153
            MWAI+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI PRDITINIGKDAPIPECPIP
Sbjct: 501  MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIP 560

Query: 1152 GQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEG 973
            G+RWKEVR+DNTVTWLAYWNDP+N +E KYVFLAASS+LKGQSDKEKYEKAR LKDYI G
Sbjct: 561  GERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAASSTLKGQSDKEKYEKARLLKDYIHG 620

Query: 972  IRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIP 796
            IR+AYTKDFT+ KD  ++Q+AVATYLID+LALRAGNEKD++EADTVGCCTLKVENV+P+P
Sbjct: 621  IRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 680

Query: 795  PNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELM 616
            PNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G++DLFD LDTSKLNAHLKELM
Sbjct: 681  PNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELM 740

Query: 615  PGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSA 436
            PGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQ ANKEVAIICNHQRTVSKSHSA
Sbjct: 741  PGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQRANKEVAIICNHQRTVSKSHSA 800

Query: 435  QMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSPEAIEKKIISTRNRI 256
            QM RL  +IDE K  L +L+ DL+RA+KGKP  K   G+ KRNL+PEA+E+KI  T  +I
Sbjct: 801  QMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNPEALERKIAQTNAKI 860

Query: 255  EKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDC 76
            EK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR EVPIEKMFNKSLLAKF+WAMD 
Sbjct: 861  EKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMFNKSLLAKFAWAMDV 920

Query: 75   DPSFRF 58
            DPSFRF
Sbjct: 921  DPSFRF 926


>ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinifera]
            gi|296082698|emb|CBI21703.3| unnamed protein product
            [Vitis vinifera]
          Length = 857

 Score =  895 bits (2314), Expect = 0.0
 Identities = 468/751 (62%), Positives = 534/751 (71%), Gaps = 15/751 (1%)
 Frame = -3

Query: 2265 KPLSARMDKGRPMAGASQTQ----KMKAMNVKPAADDSDDEK-PLSIKLNKSNSGVSSVK 2101
            KPLS R+  G P    S       +     VK   DD DD+K PLS K            
Sbjct: 119  KPLSVRLSSGLPKGKGSSNNVGLGRGGVGGVKKEEDDDDDDKIPLSSKFQLK-------- 170

Query: 2100 YYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEASSGQSS-VKKAKLSDASSS 1924
               SDE KPL  K+ QNG   +   S  VL          +S GQSS VKK K+S  S+ 
Sbjct: 171  ---SDEKKPLPLKVNQNGGTDKRDKSPTVLNKKRPLDGVNSSLGQSSLVKKPKISGQSAQ 227

Query: 1923 G-KAKQIPVKGAAK---DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1756
              K      K   K   DDDD +PISQRM                               
Sbjct: 228  PFKVTHATAKAEPKVEDDDDDDMPISQRMKKSGASSGNKPVPAKQKVTKVVSSTSFKKTK 287

Query: 1755 XXXXXXXXXXXXKEL-----PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLT 1591
                                P+SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY GKPVDLT
Sbjct: 288  DIKSKKMEKNSKYSKSTKVPPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLT 347

Query: 1590 PEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRX 1411
            PEQEEVATM+AVML+TDY++K+KF ENF  DW+K+LGKNHVIQ L  CDFTPIYEWH   
Sbjct: 348  PEQEEVATMFAVMLDTDYMQKEKFKENFMADWRKILGKNHVIQRLDDCDFTPIYEWHQEE 407

Query: 1410 XXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK 1231
                                    KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Sbjct: 408  KEKKKQMSTEEKKTLKEEKLKLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGK 467

Query: 1230 LKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLA 1051
            LK+RI+P DITINIGK++ IPECPIPG+ WKEV+HDNTVTWLA+WNDPINP+EFKYVFLA
Sbjct: 468  LKRRIHPSDITINIGKNSQIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLA 527

Query: 1050 ASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTSKDLTRQQIAVATYLIDRLALRAG 871
            ASSSLKGQSDKEKYEKARKLK+YI+ IR+ YTKDF SKD+T++QIAVATYLID+LALRAG
Sbjct: 528  ASSSLKGQSDKEKYEKARKLKNYIKDIRATYTKDFVSKDITKRQIAVATYLIDKLALRAG 587

Query: 870  NEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRL 691
            NEKD++EADTVGCCTLKVENV P PPN L+FDFLGKDSI+Y K  E +  VYKA+E+FR+
Sbjct: 588  NEKDDDEADTVGCCTLKVENVIPEPPNSLQFDFLGKDSIRYEKTVEVELPVYKAIEQFRV 647

Query: 690  GKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIA 511
            GK G+DDLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLD+ML K    G+V +K+ 
Sbjct: 648  GKSGSDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNKDTKEGDVAQKVV 707

Query: 510  IYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKD 331
            +YQHANKEVAIICNHQRT+SKSH+AQM RL  +IDE K  LN L+ DLARA+KGKP LKD
Sbjct: 708  VYQHANKEVAIICNHQRTISKSHTAQMTRLTEKIDEMKGVLNGLKTDLARAKKGKPPLKD 767

Query: 330  SSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWC 151
            + GK +RNL+PEA+E+KI  T  +IEK ERDK +KEDLK +ALGTSKINYLDPRI+VAWC
Sbjct: 768  ADGK-RRNLTPEALERKIAQTNAKIEKMERDKDTKEDLKTVALGTSKINYLDPRISVAWC 826

Query: 150  KRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 58
            KR EVPIEK+FNKSLLAKF+WAMD  P FRF
Sbjct: 827  KRQEVPIEKVFNKSLLAKFAWAMDVPPDFRF 857


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score =  893 bits (2308), Expect = 0.0
 Identities = 481/846 (56%), Positives = 568/846 (67%), Gaps = 31/846 (3%)
 Frame = -3

Query: 2502 TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVLSQRG 2323
            T+ A   N        ++ +   P A     S+            +KPL AR S  S +G
Sbjct: 116  TSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESS--------DDEKPLIARTSGCSSKG 167

Query: 2322 NSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNVKPAADDSDDEKPLS 2143
             S  AN E              S R    RP+   S+              DS+DEKPLS
Sbjct: 168  KSNHANKE---------GGDSCSIR----RPVIEESE--------------DSEDEKPLS 200

Query: 2142 IKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEASS-G 1969
             +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ P  K      KR   E  S  
Sbjct: 201  RRFPSKSSLGESTSKSYDSDEKKPLATKVQQNGSASRDGPMNKSASLLNKRAPGEVKSLN 260

Query: 1968 QSSVKKAKLSDASSSGKAKQIPVKGAAK--------------------------DDDDHI 1867
            QSS+KKAKLS   +S   KQ  VK   K                          +DDD+ 
Sbjct: 261  QSSLKKAKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNA 320

Query: 1866 PISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEL--PNSGEG 1693
            PISQR+                                                P SGEG
Sbjct: 321  PISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEG 380

Query: 1692 QKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNE 1513
            QKWTTLVHNGV+F PPY+ HG+KMLY  +P+ LTPEQEEVATM+AVML+TDY+ K +F E
Sbjct: 381  QKWTTLVHNGVMFLPPYKPHGVKMLYKXQPLTLTPEQEEVATMFAVMLDTDYMTKPRFKE 440

Query: 1512 NFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKY 1333
            NFF DWKK+LGKNH +Q+L  CDF PIYEWH +                         KY
Sbjct: 441  NFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQMTTEEKKALKEERLQQEEKY 500

Query: 1332 MWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIP 1153
            MWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PRDITINIGKDAPIPECPIP
Sbjct: 501  MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIP 560

Query: 1152 GQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEG 973
            G+RWKEVR+DNTVTWLA+WNDPIN +E KYVFLAASS+LKGQSDKEKYEKAR LKDYI G
Sbjct: 561  GERWKEVRNDNTVTWLAFWNDPINQKECKYVFLAASSTLKGQSDKEKYEKARLLKDYIHG 620

Query: 972  IRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIP 796
            IR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTVGCCTLKVENV+P+P
Sbjct: 621  IRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 680

Query: 795  PNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELM 616
            PNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G  DLFD LDTSKLNAHLKELM
Sbjct: 681  PNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGCADLFDRLDTSKLNAHLKELM 740

Query: 615  PGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSA 436
            PGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAIICNHQRTVSKSHSA
Sbjct: 741  PGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSA 800

Query: 435  QMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSPEAIEKKIISTRNRI 256
            QM RL  +IDE K  L +L+ DL+RA+KGKP  K + G+ KRNL+PE++E+KI  T  +I
Sbjct: 801  QMSRLNEKIDELKTALEELKTDLSRAKKGKPPAKGADGEPKRNLNPESLERKIAQTNAKI 860

Query: 255  EKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDC 76
            EK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR+EVPIEK+FNKSLLAKF+W+MD 
Sbjct: 861  EKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWSMDV 920

Query: 75   DPSFRF 58
            DPSFRF
Sbjct: 921  DPSFRF 926


>dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score =  887 bits (2293), Expect = 0.0
 Identities = 471/793 (59%), Positives = 551/793 (69%), Gaps = 31/793 (3%)
 Frame = -3

Query: 2364 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2185
            KPL AR S  S +G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSKGKSNHANKE---------GGDSCSIR----RPVVEESE--------- 191

Query: 2184 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2008
                 DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2007 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 1885
             S KR   E  S  QSS+KK KLS   +S   KQ  VK   K                  
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 1884 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1729
                    +DDD+ PISQR+                                        
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1728 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1555
                    P SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEEVATM+AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAV 426

Query: 1554 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1375
            ML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEREKKKQMTTEEK 486

Query: 1374 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1195
                        KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI+PRDITI
Sbjct: 487  KALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIHPRDITI 546

Query: 1194 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1015
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDP+N +E KYVFLA SS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLKGQSDKE 606

Query: 1014 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 838
            KYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 837  GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 658
            GCCTL+VENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G++DLFD 
Sbjct: 667  GCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 657  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 478
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 477  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 298
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K   G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 297  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 118
            EA+E+KI  T  +IEK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 117  NKSLLAKFSWAMD 79
            NKSLLAKF+WAM+
Sbjct: 907  NKSLLAKFAWAMN 919


>dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]
          Length = 920

 Score =  879 bits (2271), Expect = 0.0
 Identities = 475/839 (56%), Positives = 559/839 (66%), Gaps = 31/839 (3%)
 Frame = -3

Query: 2502 TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVLSQRG 2323
            T+ A   N        ++ +   P A     S+            +KPL AR S  S +G
Sbjct: 116  TSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESS--------DDEKPLIARTSGCSSKG 167

Query: 2322 NSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNVKPAADDSDDEKPLS 2143
             S  AN E              S R    RP+   S+              DS+DEKPLS
Sbjct: 168  KSNHANKE---------GGDSCSIR----RPVIEESE--------------DSEDEKPLS 200

Query: 2142 IKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEASS-G 1969
             +  +KS+ G S+ K YDSDE KPLA+K+  NG+  R+ P  K    S KR   E  S  
Sbjct: 201  RRFPSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDGPMNKSASLSNKRAPGEVKSLN 260

Query: 1968 QSSVKKAKLSDASSSGKAKQIPVKGAAK--------------------------DDDDHI 1867
            QSS+KK KLS   +S   KQ  VK   K                          +DDD+ 
Sbjct: 261  QSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNA 320

Query: 1866 PISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEL--PNSGEG 1693
            PISQR+                                                P SGEG
Sbjct: 321  PISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEG 380

Query: 1692 QKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNE 1513
            QKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEEVATM+AVML+TDY+ K +F E
Sbjct: 381  QKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKE 440

Query: 1512 NFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKY 1333
            NFF DWKK+LGKNH IQ+L  CDF PIYEWH +                         KY
Sbjct: 441  NFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEERLQQEEKY 500

Query: 1332 MWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIP 1153
            MW I+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI PRDITINIGKDAPIPECPIP
Sbjct: 501  MWVIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIP 560

Query: 1152 GQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEG 973
            G+RWKEVR+DNTVTWLAYWNDPIN +E KYVFL ASS+LKGQSDKEKYEKAR LKDYI G
Sbjct: 561  GERWKEVRNDNTVTWLAYWNDPINQKERKYVFLGASSTLKGQSDKEKYEKARLLKDYIHG 620

Query: 972  IRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIP 796
            IR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTVGCCTLKVENV+P+P
Sbjct: 621  IRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 680

Query: 795  PNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELM 616
            PNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G+ DLFD LDTSKLNAHLKELM
Sbjct: 681  PNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSADLFDRLDTSKLNAHLKELM 740

Query: 615  PGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSA 436
            PGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAIICNHQRTVSKSHSA
Sbjct: 741  PGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAIICNHQRTVSKSHSA 800

Query: 435  QMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSPEAIEKKIISTRNRI 256
            QM RL  +IDE K  L +L+ DL+RA+KGKP  K + G+ KRNL+PEA+E+KI  T  +I
Sbjct: 801  QMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGADGEPKRNLNPEALERKIAQTNAKI 860

Query: 255  EKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMD 79
            EK E DK++KEDLK +AL TSKI+YL PRITVAWCKR+EVPIEKMFNKSLLAKF+WAM+
Sbjct: 861  EKMEGDKKTKEDLKAVALSTSKISYLGPRITVAWCKRHEVPIEKMFNKSLLAKFAWAMN 919


>dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]
          Length = 920

 Score =  877 bits (2267), Expect = 0.0
 Identities = 468/793 (59%), Positives = 549/793 (69%), Gaps = 31/793 (3%)
 Frame = -3

Query: 2364 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2185
            KPL AR S  S +G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSKGKSNHANKE---------GGDSCSIR----RPVVEESE--------- 191

Query: 2184 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2008
                 DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2007 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 1885
             S KR   E  S  QSS+KK KLS   +S   KQ  VK   K                  
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 1884 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1729
                    +DDD+ PISQR+                                        
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1728 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1555
                    P SGEGQKWTTLVHNGV+F PPY+ HG+KMLY  +P+ LTPEQEEVATM+AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKQQPLTLTPEQEEVATMFAV 426

Query: 1554 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1375
            ML+TDY+ K +F ENFF DWKK+LGKNH +Q+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQMTTEEK 486

Query: 1374 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1195
                        KYM AI+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI+PRDITI
Sbjct: 487  KALKEERLQQEEKYMRAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIHPRDITI 546

Query: 1194 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1015
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDP+N +E KYVFLA SS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLKGQSDKE 606

Query: 1014 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 838
            KYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 837  GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 658
            GCCTLKVENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G++DLFD 
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 657  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 478
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 477  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 298
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K   G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 297  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 118
            EA+E+KI  T  +IEK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 117  NKSLLAKFSWAMD 79
            NKSLLAKF+WAM+
Sbjct: 907  NKSLLAKFAWAMN 919


>ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Solanum
            tuberosum]
          Length = 905

 Score =  877 bits (2266), Expect = 0.0
 Identities = 461/752 (61%), Positives = 537/752 (71%), Gaps = 16/752 (2%)
 Frame = -3

Query: 2265 KPLSARMDKGRPMAGASQTQKMKAMNV-----------KPAADDSDDEKPLSIKLN-KSN 2122
            KPLSAR+      +G S++  + A NV            P  +DSDDE PL+ +   KS+
Sbjct: 170  KPLSARVP-----SGLSKSNSIHANNVLGTSTSVQKSRPPKKEDSDDEIPLASRFQMKSS 224

Query: 2121 SGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEASSG-QSSVKKAK 1945
            +G S+ K+  S+E KP   K+ QNG      PS  VL    KRP  E S   +  +K   
Sbjct: 225  AGASTSKFSSSEEVKP---KIRQNGL-----PSATVLS---KRPPGEVSLLLRLQLKSLD 273

Query: 1944 LSDASSSGKAKQIPVKGAAK--DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXX 1771
                          VK   K  DDDD +P+SQR+                          
Sbjct: 274  FLMHLHLFLVSNXSVKTEKKTEDDDDEVPLSQRIKKAVASASASASKVSSVKKATKVVSS 333

Query: 1770 XXXXXXXXXXXXXXXXXKEL-PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDL 1594
                              +L P+SG+GQKWTTL HNGVIFPPPY+ HG+KMLY GKPVDL
Sbjct: 334  SMKKTKKKLKKPKYSKSSKLQPSSGDGQKWTTLEHNGVIFPPPYKPHGVKMLYKGKPVDL 393

Query: 1593 TPEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLR 1414
            TPEQEEVATMYAVML+T+Y+ K +F ENF  DW+K+LGKNHVIQ L +C+FTPIYEWH  
Sbjct: 394  TPEQEEVATMYAVMLDTEYLTKQQFKENFMNDWRKILGKNHVIQKLEECNFTPIYEWHQS 453

Query: 1413 XXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMG 1234
                                     KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMG
Sbjct: 454  EKEKKKQMSSEEKKALREEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMG 513

Query: 1233 KLKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFL 1054
            KLK+RI P DITINIGK  P+PECPIPGQRWKEVRHDNTVTWLA+WNDPINPREFKYVFL
Sbjct: 514  KLKRRIRPNDITINIGKGVPVPECPIPGQRWKEVRHDNTVTWLAFWNDPINPREFKYVFL 573

Query: 1053 AASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTSKDLTRQQIAVATYLIDRLALRA 874
            AASSSLKGQSDKEKYEKAR+LKDYIEGIRSAYTKDFTSKD  ++QIAVATYLID+LALRA
Sbjct: 574  AASSSLKGQSDKEKYEKARRLKDYIEGIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRA 633

Query: 873  GNEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFR 694
            GNEKD++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  +      V+KA+++FR
Sbjct: 634  GNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVAVYEPVFKAIQQFR 693

Query: 693  LGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKI 514
             GKKG DDLFD LDTSKLNAHLKELMPGLTAKVFRT+NASFTL+  L K    GE+ +K+
Sbjct: 694  SGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASFTLEQQLTKLTQGGELADKV 753

Query: 513  AIYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLK 334
            A+Y  ANKEVAIICNHQRTVSKSHS Q+ RL  +IDE KA L + + DLARA+KGKP +K
Sbjct: 754  AVYNVANKEVAIICNHQRTVSKSHSVQISRLNEKIDELKAILEEFKVDLARAKKGKPPVK 813

Query: 333  DSSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAW 154
             + GK KRNL+PEA++KKI  T  +I+  ER  ++KE+LK +ALGTSKINYLDPRITVAW
Sbjct: 814  GADGKAKRNLTPEALQKKIDQTNVKIDNIERQIETKEELKTVALGTSKINYLDPRITVAW 873

Query: 153  CKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 58
            CKR+EVPIEKMFNKSLLAKF+WAMD +PSF F
Sbjct: 874  CKRHEVPIEKMFNKSLLAKFAWAMDVEPSFTF 905