BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Achyranthes22_contig00004057
         (2882 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                 937   0.0  
ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform ...   935   0.0  
ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citr...   935   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]               934   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]       924   0.0  
gb|EOY12189.1| DNA topoisomerase I alpha isoform 1 [Theobroma ca...   914   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]                913   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...   913   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]             912   0.0  
ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis...   904   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                  901   0.0  
ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis v...   900   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]               899   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                  897   0.0  
ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinife...   895   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]             894   0.0  
dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]                  888   0.0  
ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...   880   0.0  
dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]                 880   0.0  
dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]              878   0.0  

>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score =  937 bits (2421), Expect = 0.0
 Identities = 493/836 (58%), Positives = 585/836 (69%), Gaps = 10/836 (1%)
 Frame = -3

Query: 2751 LSRGLPKKLPSTNGASSANDKSKKDVLVK--EQNRAPVAVKEEKSDKRMCXXXXXXXXDK 2578
            +S    KK P ++  +++   +     VK   Q+++   +KEEKS               
Sbjct: 106  VSTSSAKKSPVSSLPANSKPSTSGSFKVKPFNQHKSATVIKEEKSS-------------- 151

Query: 2577 PLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNVK 2398
            PL    ++++   +S                 KPLS R          +Q  K  +   K
Sbjct: 152  PLRLASAIINDSEDSD--------------DGKPLSLRHSASSSKGNTNQVSKEGS---K 194

Query: 2397 PAADDSDDEKPLSIKLN-KSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGS 2221
            P  +DSDDEKPLS +   KS  G S+ K YDSD+ KPLA KL  NG+  R+    K    
Sbjct: 195  PENEDSDDEKPLSSRFPLKSGVGESTSKAYDSDDDKPLAKKLQHNGSAMRDGQPNKYSNM 254

Query: 2220 SVKRPSAEA-SSGQSSVKKAKLSDASSSGKAKQIPVKGAAK---DDDDHIPISQRMXXXX 2053
            S KRP  +  SS Q SVKK KLS  ++    KQ  VK   K   DDDDH+PISQR+    
Sbjct: 255  SNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQASVKPEPKAEDDDDDHLPISQRIKKSP 314

Query: 2052 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKELP-NSGEGQKWTTLVHNGV 1876
                                                    ++P +SGEG+KW  L HNGV
Sbjct: 315  TSESKSSSIKKTTKVVSSSVKKVNKKSKKVMKNSKYSKSSKVPPSSGEGKKWNKLEHNGV 374

Query: 1875 IFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLLG 1696
            IFPPPY+ HGIKMLY GKPVDLTPEQEEVATM+AVML+TDY+ K +F ENFFGDWKK+LG
Sbjct: 375  IFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILG 434

Query: 1695 KNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEK 1516
            KNHVIQ+L  CDF+PIYEWH                           KYMWA +DG KEK
Sbjct: 435  KNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEEKKALKEEKLKQEEKYMWAWVDGKKEK 494

Query: 1515 VGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHDN 1336
            VGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIGKDAPIPECP+PG+RWKEVRHDN
Sbjct: 495  VGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDN 554

Query: 1335 TVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS 1156
            TVTWLA+WNDPINP+EFKYVFLAASS+LKG SDKEKYEKAR LKDYI+GIR+AYTKDF S
Sbjct: 555  TVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKDFAS 614

Query: 1155 KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKD 976
            KD T++QIAVATYLID+LALRAGNEKD++EADTVGCCTLKVENV+P+PPNIL+FDFLGKD
Sbjct: 615  KDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKD 674

Query: 975  SIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFN 796
            SI+Y  + E +  V+KA+++FR GK+G+ DLFD+LDTSKLNAHLKELMPGLTAKVFRT+N
Sbjct: 675  SIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYN 734

Query: 795  ASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEA 616
            AS TLDDML++    G+V EK+ +YQHANKEVAIICNHQRTVSKSHSAQM RL  +I+E 
Sbjct: 735  ASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEEL 794

Query: 615  KAELNDLEKDLARARKGKPLL--KDSSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSK 442
            KA + +L+ DL+R +KGKP L  K++ GK KRNL+PE++EKKI  T  +IEK ERDK++K
Sbjct: 795  KAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPESLEKKIAQTNAKIEKMERDKETK 854

Query: 441  EDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 274
            EDLK +ALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKF+WAMD DPSFRF
Sbjct: 855  EDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWAMDVDPSFRF 910


>ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform X1 [Citrus sinensis]
            gi|568842074|ref|XP_006474978.1| PREDICTED: DNA
            topoisomerase 1-like isoform X2 [Citrus sinensis]
            gi|568842076|ref|XP_006474979.1| PREDICTED: DNA
            topoisomerase 1-like isoform X3 [Citrus sinensis]
            gi|568842078|ref|XP_006474980.1| PREDICTED: DNA
            topoisomerase 1-like isoform X4 [Citrus sinensis]
          Length = 902

 Score =  935 bits (2417), Expect = 0.0
 Identities = 509/840 (60%), Positives = 580/840 (69%), Gaps = 19/840 (2%)
 Frame = -3

Query: 2736 PKKLPSTNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCS 2557
            P +  +T+ A ++  KS     VK   R+PV      S +             PL  R  
Sbjct: 76   PSQKATTSSAKASPSKSPMRSPVKSPVRSPVKSPVANSKES-----------SPLDDRLK 124

Query: 2556 VLSQRGNSTVANVE-------VKPXXXXXXXDKPLSARMDKGRPM-----AGASQTQK-M 2416
               Q     V   E       +K        DKPLSAR+ KG         GAS+    +
Sbjct: 125  QSPQHNALAVVKKEEIKDGNGLKSDDNDSEDDKPLSARL-KGNSKNVNQGIGASKADAAI 183

Query: 2415 KAMNVKPAADDSDDEKPLSIKLNKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSM 2236
              +NVK   +DSDDE PLS +  KSN+G S  K  DSDE KPLASK+ QNG+  R T   
Sbjct: 184  SEVNVKTDPEDSDDEVPLSSRFPKSNAGTSGAKPIDSDEKKPLASKVQQNGSTSRET-QQ 242

Query: 2235 KVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK-DDDDHIPISQRMX 2062
            K     VKRP  +ASS G SS KK K+SD S   K KQ+ VK   K DDDDHIPISQRM 
Sbjct: 243  KSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKKADDDDHIPISQRMK 302

Query: 2061 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKE--LPNSGEGQK-WTTL 1891
                                                          LP SG+GQK WTTL
Sbjct: 303  NSAPSVKKSVTNTAKATKSVSSSSNKINKKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTL 362

Query: 1890 VHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDW 1711
            VHNGVIFPPPY  HG+KMLY GK V+LTPEQEEVATM+AVML+TDY++K KF ENF+ DW
Sbjct: 363  VHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDW 422

Query: 1710 KKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILD 1531
            +KLLGKNHVIQ+L  CDF PIY+WH                           KYMWAI+D
Sbjct: 423  RKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEKLKQEEKYMWAIVD 482

Query: 1530 GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKE 1351
            GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIGKD PIPECPIPG+ WKE
Sbjct: 483  GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVPIPECPIPGESWKE 542

Query: 1350 VRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYT 1171
            V+HDNTVTWLA+WNDPINP+EFKYVFLAASSSLKGQSDKEKYEKARKLKDYI  IR+AYT
Sbjct: 543  VKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHSIRAAYT 602

Query: 1170 KDFTSKDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFD 991
            KDF S+D TR+QIAVATYLID+LALRAGNEKD++EADTVGCCTLKV NV+ IPPN L+FD
Sbjct: 603  KDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLKFD 662

Query: 990  FLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKV 811
            FLGKDSI+Y    E +  VYKA+ +F+ GKK NDDLFD LDT+KLNAHLKELMPGLTAKV
Sbjct: 663  FLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKV 722

Query: 810  FRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQT 631
            FRT+NAS TLD ML KG G G+V  KI +YQ ANKEVAIICNHQRTVSK+HSAQM RL  
Sbjct: 723  FRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTE 782

Query: 630  RIDEAKAELNDLEKDLARARKGK-PLLKDSSGKQKRNLSPEAIEKKIISTRNRIEKFERD 454
            +I++ K  L DL  DL RA+KGK PL+KDS GK+KRNL+PEA+E+K+  T  +IEK ERD
Sbjct: 783  KIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERD 842

Query: 453  KQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 274
             ++KEDLK +ALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKF+WAMD DP FRF
Sbjct: 843  MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPEFRF 902


>ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|567920950|ref|XP_006452481.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555705|gb|ESR65719.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555707|gb|ESR65721.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 902

 Score =  935 bits (2416), Expect = 0.0
 Identities = 509/840 (60%), Positives = 581/840 (69%), Gaps = 19/840 (2%)
 Frame = -3

Query: 2736 PKKLPSTNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCS 2557
            P +  +T+ A ++  KS     VK   R+PV      S +             PL  R  
Sbjct: 76   PSQKATTSSAKASPLKSPMRSPVKSPVRSPVKSPVANSKES-----------SPLDDRLK 124

Query: 2556 VLSQRGNSTVANVE-------VKPXXXXXXXDKPLSARMDKGRPM-----AGASQTQK-M 2416
             L Q     V   E       +K        DKPLSAR+ KG         GAS+    +
Sbjct: 125  QLPQHNALAVVKKEEIKDGNGLKSDDNDSEDDKPLSARL-KGNTKNVNQGIGASKADAAI 183

Query: 2415 KAMNVKPAADDSDDEKPLSIKLNKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSM 2236
              +NVK   +DSDDE PLS +  KSN+G S  K  DSDE KPLASK+ QNG+  R T   
Sbjct: 184  SEVNVKTDPEDSDDEVPLSSRFPKSNAGTSGAKPIDSDEKKPLASKVQQNGSTSRET-QQ 242

Query: 2235 KVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK-DDDDHIPISQRMX 2062
            K     VKRP  +ASS G SS KK K+SD S   K KQ+ VK   K DDDDHIPISQRM 
Sbjct: 243  KSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKKADDDDHIPISQRMK 302

Query: 2061 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKE--LPNSGEGQK-WTTL 1891
                                                          LP SG+GQK WTTL
Sbjct: 303  NSAPSVKKSVTNTAKATKSVSSSSKKINKKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTL 362

Query: 1890 VHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDW 1711
            VHNGVIFPPPY  HG+KMLY GK V+LTPEQEEVATM+AVML+TDY++K KF ENF+ DW
Sbjct: 363  VHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDW 422

Query: 1710 KKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILD 1531
            +KLLGKNHVIQ+L  CDF PIY+WH                           KYMWAI+D
Sbjct: 423  RKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEKLKQEEKYMWAIVD 482

Query: 1530 GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKE 1351
            GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIGKD PIPECPIPG+ WKE
Sbjct: 483  GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVPIPECPIPGESWKE 542

Query: 1350 VRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYT 1171
            V+HDNTVTWLA+WNDPINP+EFKYVFLAASSSLKGQSD+EKYEKARKLKDYI  IR+AYT
Sbjct: 543  VKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDREKYEKARKLKDYIHSIRAAYT 602

Query: 1170 KDFTSKDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFD 991
            KDF S+D TR+QIAVATYLID+LALRAGNEKD++EADTVGCCTLKV NV+ IPPN L+FD
Sbjct: 603  KDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLKFD 662

Query: 990  FLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKV 811
            FLGKDSI+Y    E +  VYKA+ +F+ GKK NDDLFD LDT+KLNAHLKELMPGLTAKV
Sbjct: 663  FLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKV 722

Query: 810  FRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQT 631
            FRT+NAS TLD ML KG G G+V  KI +YQ ANKEVAIICNHQRTVSK+HSAQM RL  
Sbjct: 723  FRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTE 782

Query: 630  RIDEAKAELNDLEKDLARARKGK-PLLKDSSGKQKRNLSPEAIEKKIISTRNRIEKFERD 454
            +I++ K  L DL  DL RA+KGK PL+KDS GK+KRNL+PEA+E+K+  T  +IEK ERD
Sbjct: 783  KIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERD 842

Query: 453  KQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 274
             ++KEDLK +ALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKF+WAMD DP FRF
Sbjct: 843  MKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPEFRF 902


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score =  934 bits (2414), Expect = 0.0
 Identities = 502/843 (59%), Positives = 582/843 (69%), Gaps = 25/843 (2%)
 Frame = -3

Query: 2727 LPSTNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVLS 2548
            +PSTNG SS+  K K   L     ++P+A  +  +                   R    S
Sbjct: 58   VPSTNGQSSSASKGKTTKL--SSMKSPIASPKASTSFAKASPVANPKVSSSSDDRSKHSS 115

Query: 2547 QRGNSTVANVE---VKPXXXXXXXD---KPLSARMDKGRPMAGASQTQKMKAMNVKPAA- 2389
            ++    V   E   V P           KPLSAR+  G    G+S       +N  PA+ 
Sbjct: 116  KQNTINVVKEEKELVNPAAEPYGDSEDEKPLSARLFTGLTK-GSSNNANKGLINSSPASL 174

Query: 2388 -----------DDSDDEKPLSIKLN-KSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNT 2245
                       DDSDDE PLS K   K+N+G S+VK Y+SD++K L S   QNG+I R +
Sbjct: 175  PVPKPEINRYSDDSDDEIPLSSKFRLKANAGTSTVKSYESDDNKTLVSNFQQNGSINRGS 234

Query: 2244 PSMKVLGSSVKRPSAEA-SSGQSSVKKAKLSDASSSGKAKQIPVKGAAK---DDDDHIPI 2077
             S   +    KRP  E  SS QSSVKK KLSDAS+    KQ   K   K    DDDH+PI
Sbjct: 235  KSSIKVN---KRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKADDSDDDHVPI 291

Query: 2076 SQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEL--PNSGEGQK 1903
            SQRM                                                P+SGEG+K
Sbjct: 292  SQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSKSSKVPPSSGEGKK 351

Query: 1902 WTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENF 1723
            W TLVHNGVIFPPPY+ HG+KMLY GKPVDLTPEQEEVATM+AVML+TDY+ K KF ENF
Sbjct: 352  WNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMTKSKFKENF 411

Query: 1722 FGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMW 1543
              DW+K+LGKNHVIQ+L  CDFTPIYEWH R                         KYMW
Sbjct: 412  MDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEERLKQEEKYMW 471

Query: 1542 AILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQ 1363
            AI++GVKEKVGNFRVEPP LFRGRGEHPKMGKLKK I P DITINIGKDAPIPECPIPG+
Sbjct: 472  AIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIPECPIPGE 531

Query: 1362 RWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIR 1183
             WKE+RHDNTVTWLA+WNDPI PREFKYVFLAASSSLKGQSDKEKYEKAR LKD+I+GIR
Sbjct: 532  SWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLKDFIQGIR 591

Query: 1182 SAYTKDFTSKDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNI 1003
            +AYTKDF SKD+T++QIAVATYLID+LALRAGNEKD++EADTVGCCTLKVENV+P PP+I
Sbjct: 592  AAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPKPPSI 651

Query: 1002 LEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGL 823
            L+FDFLGKDSI+Y  + E +  VYKA+++FR GK+G DDLFD LDTSKLNAHLK LMPGL
Sbjct: 652  LKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNAHLKGLMPGL 711

Query: 822  TAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQME 643
            TAKVFRT+NAS TLD+ML++    G V EKI +YQHANKEVAIICNHQRTVSKSH AQM 
Sbjct: 712  TAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSKSHPAQMT 771

Query: 642  RLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSPEAIEKKIISTRNRIEKF 463
            RL  +IDE K  L+ L+ DLARA+KGKP L+D+ GK KRNL+PEA+E+KI  T  +IEK 
Sbjct: 772  RLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKIGQTNAKIEKM 831

Query: 462  ERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPS 283
            ERDK++KE LK IALGTSKI+YLDPRITVAWCKR+EVPIEK+FNKSLLAKF+W+MD DPS
Sbjct: 832  ERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSLLAKFAWSMDVDPS 891

Query: 282  FRF 274
            FRF
Sbjct: 892  FRF 894


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score =  924 bits (2389), Expect = 0.0
 Identities = 502/867 (57%), Positives = 589/867 (67%), Gaps = 53/867 (6%)
 Frame = -3

Query: 2715 NGASSANDK-----SKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVL 2551
            NG SS+  K     S K   VK    +P   K   S  +           KP ++  S  
Sbjct: 62   NGESSSAQKGRIQPSAKTPPVKSPLSSP---KASNSSAKASPITSPGANSKPSASATSTA 118

Query: 2550 SQRGN--STVANVEVKPXXXXXXXD---------KPLSARM----DKGRPMAGASQTQKM 2416
             Q+ +  S+ A +E KP       +         KPLSAR      KG+      +    
Sbjct: 119  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 178

Query: 2415 KAMN--VKPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNT 2245
             ++   V   ++DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ 
Sbjct: 179  CSIRRPVIEESEDSEDEKPLSCRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDG 238

Query: 2244 PSMKVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK----------- 2101
            P  K    S KRP  EA S  QSSVKK KLS   +S   KQ  VK   K           
Sbjct: 239  PMNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 298

Query: 2100 ---------------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1966
                           DDDD++PISQR+                                 
Sbjct: 299  QRGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNKNSK 358

Query: 1965 XXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEE 1792
                           P SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEE
Sbjct: 359  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEE 418

Query: 1791 VATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXX 1612
            VATM+AVML+TDY+ K  F ENFF DWKK+LGKNH+IQ+L  CDF PIYEWH +      
Sbjct: 419  VATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKK 478

Query: 1611 XXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1432
                               KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI
Sbjct: 479  QMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 538

Query: 1431 YPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSL 1252
             PRDITINIGKDAPIPECPIPG+RWKEVR+ NTVTWLAYWNDPIN +EFKYVFLAASS+L
Sbjct: 539  RPRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTL 598

Query: 1251 KGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKD 1075
            KGQSDKEKYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD
Sbjct: 599  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 658

Query: 1074 EEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKG 895
            ++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + + +P V+KA+++FR GK+G
Sbjct: 659  DDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 718

Query: 894  NDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQH 715
            ++DLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    GEV E + +YQH
Sbjct: 719  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVVYQH 778

Query: 714  ANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGK 535
            ANKEVAIICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K + GK
Sbjct: 779  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGADGK 838

Query: 534  QKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNE 355
             KRNL+PEA+E+KI  T  +IEK ERDK++KEDLK +ALGTSKINYLDPRITVAWCKR+E
Sbjct: 839  AKRNLNPEALERKITQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 898

Query: 354  VPIEKMFNKSLLAKFSWAMDCDPSFRF 274
            VPIEK+FNKSLLAKF+W+MD DPSFRF
Sbjct: 899  VPIEKIFNKSLLAKFAWSMDVDPSFRF 925


>gb|EOY12189.1| DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
            gi|508720293|gb|EOY12190.1| DNA topoisomerase I alpha
            isoform 1 [Theobroma cacao]
          Length = 904

 Score =  914 bits (2361), Expect = 0.0
 Identities = 488/837 (58%), Positives = 584/837 (69%), Gaps = 12/837 (1%)
 Frame = -3

Query: 2748 SRGLPKKLPSTN--GASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDK- 2578
            ++ LP K P  N   ++S ND+SK+ +   +QN    AVKE +S  +          D  
Sbjct: 98   TKALPVKSPVVNFKASTSLNDQSKQAL---KQNMT-TAVKEGRSPIKGTTEPNSDDDDDD 153

Query: 2577 ---PLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKM-KA 2410
               PLSAR   +S +GN                          KG   +  +Q++++   
Sbjct: 154  DSLPLSARLKGISNQGN--------------------------KGASTSAPAQSRRLVPK 187

Query: 2409 MNVKPAADDSDDEKPLSIKLN-KSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMK 2233
              VK +A+D DDE PLS + N KSN+G SS + +D DE KPLASK+ QNG+I +      
Sbjct: 188  TEVKVSAEDPDDEAPLSARFNVKSNTGTSSSRLHDCDEKKPLASKIQQNGSIMKGKQQNS 247

Query: 2232 VLGSSVKRPSAEASSGQSSVKKAKLSDASSSGKAKQIPVKGA-AKDDDDHIPISQRMXXX 2056
               S  +      SS  SS KK K SDA ++ K KQ+ VK   A +DDDH+PI+QRM   
Sbjct: 248  STLSGKRPLDKGNSSDHSSAKKPKTSDAPTTMKTKQVTVKAEKADEDDDHMPIAQRMKKS 307

Query: 2055 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEL--PNSGEGQK-WTTLVH 1885
                                                         P+SG+GQK W+TLVH
Sbjct: 308  TASNSKLSSMKQKTTKVVSSSFKKINKKSKKEMKSSKYIKSTKVPPSSGDGQKKWSTLVH 367

Query: 1884 NGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDWKK 1705
            NGVIFP PY  HG+KMLY+G+PVDLTPEQEEVATM+AVM +TDY+ K +F +NF+ DW K
Sbjct: 368  NGVIFPSPYTPHGVKMLYDGRPVDLTPEQEEVATMFAVMKDTDYMSKTQFKKNFWEDWSK 427

Query: 1704 LLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGV 1525
            LLGKNH I+DL +CDFTPIYEWHL+                         K+MWAI+DGV
Sbjct: 428  LLGKNHTIKDLDRCDFTPIYEWHLQEKEKKKQMSSEEKKALKEEKLKQEEKFMWAIVDGV 487

Query: 1524 KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKEVR 1345
            KEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI P DITINIGKDAPIPECPIPG+RWK+++
Sbjct: 488  KEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGERWKDIK 547

Query: 1344 HDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKD 1165
            HDNTVTWLA+WNDPINP+EFKYVFLAASSSLKGQSDKEKYEKAR LKDYI+ IR+AYTKD
Sbjct: 548  HDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRAAYTKD 607

Query: 1164 FTSKDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFDFL 985
            FT+KD+ ++QIAVATYLID+LALRAGNEKD++EADTVGCCTLKV NV+ IPPN L+FDFL
Sbjct: 608  FTTKDVMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLKFDFL 667

Query: 984  GKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFR 805
            GKDSI+Y    E +  VYKA+ +F+ GK  +DDLFD LDTSKLNAHLKELMPGLTAKVFR
Sbjct: 668  GKDSIQYVNTVEVELPVYKAIGQFQTGKSKSDDLFDKLDTSKLNAHLKELMPGLTAKVFR 727

Query: 804  TFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQTRI 625
            T+NAS TLD+ML K    G+V EK+ +YQ ANKEVAIICNHQR++SKSHSAQM RL  +I
Sbjct: 728  TYNASITLDEMLNKETKDGDVAEKVVVYQRANKEVAIICNHQRSISKSHSAQMSRLTEKI 787

Query: 624  DEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQS 445
             E K  L +L+ DL RA+KGKP LKD+ GKQKRNL+P+AI+KKI  T  +IEK ERD Q+
Sbjct: 788  TELKGVLKELKIDLDRAKKGKPPLKDADGKQKRNLTPQAIQKKIDQTNAKIEKMERDMQT 847

Query: 444  KEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 274
            KEDLK +ALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKF+WAMD DP FRF
Sbjct: 848  KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF 904


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score =  913 bits (2360), Expect = 0.0
 Identities = 494/869 (56%), Positives = 587/869 (67%), Gaps = 55/869 (6%)
 Frame = -3

Query: 2715 NGASSANDK-----SKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVL 2551
            NG SS+  K     S K   VK    +P   K   S  +           KP ++  S  
Sbjct: 62   NGESSSAQKGRIQPSAKTPPVKSPLSSP---KASNSSAKASPITSPGANSKPSASATSTA 118

Query: 2550 SQRGN--STVANVEVKPXXXXXXXD---------KPLSARM----DKGRPMAGASQTQKM 2416
             Q+ +  S+ A +E KP       +         KPLSAR      KG+      +    
Sbjct: 119  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 178

Query: 2415 KAMN--VKPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNT 2245
             ++   V   ++DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG++ R+ 
Sbjct: 179  CSIRRRVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSVSRDG 238

Query: 2244 PSMKVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK----------- 2101
            P  K    S KRP  E  S  QSSVKK KLS   +S   KQ  VK   +           
Sbjct: 239  PMNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIP 298

Query: 2100 -----------------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1972
                             +DDD++PI+QR+                               
Sbjct: 299  LSQRGKKSQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKN 358

Query: 1971 XXXXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQ 1798
                             P SGEGQKWTTLVHNGVIFPPPY  HG+KMLY  +P+ LTPEQ
Sbjct: 359  SKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQ 418

Query: 1797 EEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXX 1618
            EEVATM+AVML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +    
Sbjct: 419  EEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEK 478

Query: 1617 XXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK 1438
                                 KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK
Sbjct: 479  KKQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKK 538

Query: 1437 RIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASS 1258
            RI PRDITINIGKDAPIPECPIPG+RWKEVR+DNTVTWLA+W DPIN +EFKYVFLAASS
Sbjct: 539  RIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASS 598

Query: 1257 SLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNE 1081
            +LKGQSDKEKYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNE
Sbjct: 599  TLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNE 658

Query: 1080 KDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGK 901
            KD++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + + +P V+KA+++FR GK
Sbjct: 659  KDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGK 718

Query: 900  KGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIY 721
            +G++DLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    GEV EK+ +Y
Sbjct: 719  EGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVY 778

Query: 720  QHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSS 541
            QHANKEVAIICNHQRTVSKSHSAQM RL  +IDE K  + +L+ DL+R +KGKP  K + 
Sbjct: 779  QHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSKGAD 838

Query: 540  GKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKR 361
            GK KRNL+PEA+E+K+     +IEK ERDK++KEDLK +ALGTSKINYLDPRITVAWCKR
Sbjct: 839  GKPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKR 898

Query: 360  NEVPIEKMFNKSLLAKFSWAMDCDPSFRF 274
            +EVPIEK+FNKSLLAKF+W+MD DPSFRF
Sbjct: 899  HEVPIEKIFNKSLLAKFAWSMDVDPSFRF 927


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score =  913 bits (2359), Expect = 0.0
 Identities = 494/860 (57%), Positives = 585/860 (68%), Gaps = 53/860 (6%)
 Frame = -3

Query: 2715 NGASSANDK-----SKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVL 2551
            NG +S+  K     S K   VK    +P   K   S  +           KP ++  S  
Sbjct: 63   NGENSSAQKGRIQPSAKTPPVKSPLSSP---KASNSSAKASPITSAGANSKPSASATSTA 119

Query: 2550 SQRGN--STVANVEVKPXXXXXXXD---------KPLSARM----DKGRPMAGASQTQKM 2416
             Q+ +  S+ A +E KP       +         KPLSAR      KG+      +    
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 179

Query: 2415 KAMN--VKPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNT 2245
             ++   V   ++DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+  NG+  R++
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDS 239

Query: 2244 PSMKVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK----------- 2101
            P  K    S KRP  E  S  QSS+KK KLS   +S   KQ  VK   K           
Sbjct: 240  PMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 2100 ---------------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1966
                           +DDD++PISQR+                                 
Sbjct: 300  QRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 1965 XXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEE 1792
                           P SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEE 419

Query: 1791 VATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXX 1612
            VATM+AVML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +      
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1611 XXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1432
                               KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI
Sbjct: 480  QMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 539

Query: 1431 YPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSL 1252
             PRDITINIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDPIN +EFKYVFLAASS+L
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTL 599

Query: 1251 KGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKD 1075
            KGQSDKEKYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 1074 EEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKG 895
            ++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + + +P V+KA+++FR GK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEG 719

Query: 894  NDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQH 715
            ++DLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    GEV EK+ +YQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQH 779

Query: 714  ANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGK 535
            ANKEVAIICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKPL K + GK
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGK 839

Query: 534  QKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNE 355
             KRNL+PEA+E+KI  T  +IEK ERDK++KEDLK +ALGTSKINYLDPRITVAWCKR+E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 899

Query: 354  VPIEKMFNKSLLAKFSWAMD 295
            VPIEK+FNKSLLAKF+WAM+
Sbjct: 900  VPIEKIFNKSLLAKFAWAMN 919


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score =  912 bits (2357), Expect = 0.0
 Identities = 494/860 (57%), Positives = 584/860 (67%), Gaps = 53/860 (6%)
 Frame = -3

Query: 2715 NGASSANDK-----SKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVL 2551
            NG +S+  K     S K   VK    +P   K   S  +           KP ++  S  
Sbjct: 63   NGENSSAQKGRIQPSAKTPPVKSPLSSP---KASNSSAKASPITSPGANSKPSASATSTA 119

Query: 2550 SQRGN--STVANVEVKPXXXXXXXD---------KPLSARM----DKGRPMAGASQTQKM 2416
             Q+ +  S+ A +E KP       +         KPLSAR      KG+      +    
Sbjct: 120  KQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDS 179

Query: 2415 KAMN--VKPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNT 2245
             ++   V   ++DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+  NG+  R++
Sbjct: 180  CSIRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDS 239

Query: 2244 PSMKVLGSSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK----------- 2101
            P  K    S KRP  E  S  QSS+KK KLS   +S   KQ  VK   K           
Sbjct: 240  PMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLS 299

Query: 2100 ---------------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1966
                           +DDD++PISQR+                                 
Sbjct: 300  QRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSK 359

Query: 1965 XXXXXXXXXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEE 1792
                           P SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEE
Sbjct: 360  KVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEE 419

Query: 1791 VATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXX 1612
            VATM+AVML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +      
Sbjct: 420  VATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKK 479

Query: 1611 XXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 1432
                               KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI
Sbjct: 480  QMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 539

Query: 1431 YPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSL 1252
             PRDITINIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDPIN +EFKYVFLAASS+L
Sbjct: 540  RPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTL 599

Query: 1251 KGQSDKEKYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKD 1075
            KGQSDKEKYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD
Sbjct: 600  KGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKD 659

Query: 1074 EEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKG 895
            ++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + + +P V+KA+ +FR GK+G
Sbjct: 660  DDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSGKEG 719

Query: 894  NDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQH 715
            ++DLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    GEV EK+ +YQH
Sbjct: 720  SEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQH 779

Query: 714  ANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGK 535
            ANKEVAIICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKPL K + GK
Sbjct: 780  ANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGK 839

Query: 534  QKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNE 355
             KRNL+PEA+E+KI  T  +IEK ERDK++KEDLK +ALGTSKINYLDPRITVAWCKR+E
Sbjct: 840  PKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHE 899

Query: 354  VPIEKMFNKSLLAKFSWAMD 295
            VPIEK+FNKSLLAKF+WAM+
Sbjct: 900  VPIEKIFNKSLLAKFAWAMN 919


>ref|XP_004149585.1| PREDICTED: DNA topoisomerase 1-like [Cucumis sativus]
            gi|449503189|ref|XP_004161878.1| PREDICTED: DNA
            topoisomerase 1-like [Cucumis sativus]
          Length = 889

 Score =  904 bits (2337), Expect = 0.0
 Identities = 496/835 (59%), Positives = 570/835 (68%), Gaps = 17/835 (2%)
 Frame = -3

Query: 2727 LPSTNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCSVLS 2548
            L STNG SS N K    +      R+ +   ++ S                L A  S+ S
Sbjct: 58   LCSTNGQSSNNQKRMTSLPKTSPMRSEIG-SQKASRSSPIPEPLTKSLGTSLKASHSMDS 116

Query: 2547 QRGNSTVA-----NVEVKPXXXXXXXD--KPLSARMDKGRP-MAGASQTQKMKAMNVKPA 2392
            +  +   A     NV + P       +  KPLS R+ KG P          +    VK +
Sbjct: 117  RPKSLVNAVVKEENVSINPSQENSDSEDDKPLSIRL-KGNPNQPNKGLVSTVPKNKVKKS 175

Query: 2391 ADDSDDEKPLSIKLN-KSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSV 2215
              DSDDE PLS K   K  SGV   K +  DE KPL  K+ QNG+  R+      + SS 
Sbjct: 176  LADSDDEVPLSSKFQMKHASGVLGSKQHGFDEKKPLVPKVHQNGSTSRDKLQKPAVLSS- 234

Query: 2214 KRPSAEASS---GQSSVKKAKLSDASSSGKAKQIPVKGAAK--DDDDHIPISQRMXXXXX 2050
            KRP     S    Q   KK KL+D+SS   +K + +K   +  DDDD IPISQRM     
Sbjct: 235  KRPLPNEDSHSPSQFPTKKPKLTDSSSPLNSKLVSLKAKQEVDDDDDDIPISQRMKKVSA 294

Query: 2049 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKE--LPNSGEGQK-WTTLVHNG 1879
                                                      LP++G+GQK WTTLVHNG
Sbjct: 295  TVNKSSSSKPTISKVVSSSIKKTFKKSKKPVKKSKYVKSTKLLPSAGDGQKKWTTLVHNG 354

Query: 1878 VIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLL 1699
            VIFPPPYQ+HG+KMLY GKPVDLTP QEEVATM+AVM +TDY+ K KF ENF+ DW+KLL
Sbjct: 355  VIFPPPYQTHGVKMLYKGKPVDLTPPQEEVATMFAVMKDTDYMLKPKFKENFWNDWRKLL 414

Query: 1698 GKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKE 1519
            GKNHVIQ+L  CDFTPIY+W+                           KYMWAILDGVKE
Sbjct: 415  GKNHVIQNLDDCDFTPIYDWYQMEKEKKKQMTTEEKKAVKEEKLKQEEKYMWAILDGVKE 474

Query: 1518 KVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHD 1339
            KVGNFRVEPPGLFRGRGEHPKMGKLK+RI P DITINIGK APIPECPIPG+RWKEVRHD
Sbjct: 475  KVGNFRVEPPGLFRGRGEHPKMGKLKRRICPSDITINIGKGAPIPECPIPGERWKEVRHD 534

Query: 1338 NTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFT 1159
            NTVTWLA+WNDPIN +EFKYVFLAASSSLKGQSDKEKYEKAR LKDYI+ IR+AYTKDFT
Sbjct: 535  NTVTWLAFWNDPINQKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRNAYTKDFT 594

Query: 1158 SKDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGK 979
            SKD TR+QIAVATYLID+LALRAGNEKD++EADTVGCCTLKVENVK +PPN+LEF+FLGK
Sbjct: 595  SKDPTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVKAVPPNLLEFNFLGK 654

Query: 978  DSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTF 799
            DSI+Y    E +  V+KA+ +F+ GK G DDLFD LDTSKLNAHLK+LMPGLTAKVFRT+
Sbjct: 655  DSIRYENTVEVELPVFKAITQFQSGKSGTDDLFDKLDTSKLNAHLKDLMPGLTAKVFRTY 714

Query: 798  NASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDE 619
            NAS TLDDML +G  +GEV EKI  YQHANKEVAIICNHQRTVSKSH AQM RL  +I E
Sbjct: 715  NASITLDDMLNRGTKNGEVSEKIVTYQHANKEVAIICNHQRTVSKSHGAQMTRLNEKISE 774

Query: 618  AKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKE 439
             +  L +L+ DL RA+KGKP LK S GKQKRNL+PEA+EKKI  T  +IEK ERD ++KE
Sbjct: 775  LRDILKELKIDLDRAKKGKPPLKGSDGKQKRNLTPEALEKKISQTNAKIEKIERDMKTKE 834

Query: 438  DLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 274
            DLK +ALGTSKINYLDPRITVAWCKR+EVPIEK+FNKSLLAKF+WAMD DP FRF
Sbjct: 835  DLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPDFRF 889


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score =  901 bits (2328), Expect = 0.0
 Identities = 487/860 (56%), Positives = 574/860 (66%), Gaps = 33/860 (3%)
 Frame = -3

Query: 2754 LLSRGLPKKLPS--TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXD 2581
            + S G   KL +  T+ A   N        ++ +   P A     S+            +
Sbjct: 102  ITSPGANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPPAKANSNSESS--------DDE 153

Query: 2580 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2401
            KPL AR S  S +G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSKGKSNHANKE---------GGDSCSIR----RPVVEESE--------- 191

Query: 2400 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2224
                 DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2223 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 2101
             S KR   E  S  QSS+KK KLS   +S   KQ  VK   K                  
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2100 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1945
                    +DDD+ PISQR+                                        
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1944 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1771
                    P SGEGQKWTTLVHNGV+FPPPY+ HG+KMLY  +P+ LTPEQEEVATM+A 
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAA 426

Query: 1770 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1591
            ML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEREKKKQMTTEEK 486

Query: 1590 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1411
                        KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI+PRDITI
Sbjct: 487  KALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIHPRDITI 546

Query: 1410 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1231
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDP+N +E KYVFLA SS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLKGQSDKE 606

Query: 1230 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 1054
            KYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1053 GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 874
            GCCTLKVENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G++DLFD 
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 873  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 694
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 693  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 514
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K   G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 513  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 334
            EA+E+KI  T  +IEK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 333  NKSLLAKFSWAMDCDPSFRF 274
            NKSLLAKF+WAMD DPSFRF
Sbjct: 907  NKSLLAKFAWAMDVDPSFRF 926


>ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis vinifera]
          Length = 883

 Score =  900 bits (2325), Expect = 0.0
 Identities = 460/736 (62%), Positives = 533/736 (72%), Gaps = 11/736 (1%)
 Frame = -3

Query: 2448 PMAGASQTQKMKAMNVKPAADDSDDEKPLSIKLN-KSNSGVSSVKYYDSDEHKPLASKLL 2272
            P +   Q+QK K  N K  +DDS+DE PLS K   K+  G S  K  + DE KPL S L 
Sbjct: 149  PASSRPQSQKAKVNN-KNLSDDSEDEIPLSSKFRLKTGMGASLDKLDNFDEKKPLTSTLK 207

Query: 2271 QNGTIKRNTPSMKVLGSSVKRPSAEAS-SGQSSVKKAKLSDASSSGKAKQIPVKGAAKDD 2095
             NG  K++   +K      KRP  +A+ S  SS KK KL D S  GK KQ+ VK   KDD
Sbjct: 208  PNGISKKDDERVKSPKGQNKRPLGQANTSHHSSSKKPKLLDGSVKGKVKQVSVKAEQKDD 267

Query: 2094 DD--------HIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1939
            DD        + P  +R+                                          
Sbjct: 268  DDDDNDDDDEYTPTVKRLKKSVSSDNKKASKTKVIPSSRKKATKKAKKSKKLAKSSKYSK 327

Query: 1938 XKELP-NSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAVMLE 1762
              ++P NSGEGQKWTTL HNGVIFPPPY+ HG+KMLYNG+PVDLTPEQEEVATM+AVM +
Sbjct: 328  STKVPPNSGEGQKWTTLEHNGVIFPPPYKPHGVKMLYNGRPVDLTPEQEEVATMFAVMKD 387

Query: 1761 TDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXXXXX 1582
            TDY  K +F ENF  DW+  LGKNHVI+    CDFTPIYEWH +                
Sbjct: 388  TDYATKPRFIENFMNDWRVRLGKNHVIKKFELCDFTPIYEWHEKEKEKKKQMTTEEKKAL 447

Query: 1581 XXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITINIG 1402
                     KYMWA++DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIG
Sbjct: 448  KEEKLKQEDKYMWAVVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIG 507

Query: 1401 KDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKEKYE 1222
            K+AP+PECPIPG+RWKEVRHDNTVTWLA+WNDPINP+EFKYVFLAASSSLKGQSDKEKYE
Sbjct: 508  KEAPVPECPIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYE 567

Query: 1221 KARKLKDYIEGIRSAYTKDFTSKDLTRQQIAVATYLIDRLALRAGNEKDEEEADTVGCCT 1042
            KAR LKDYI+ IR+ YTKDFT+KD  ++QIAVATYLID+LALRAGNEKD++EADTVGCCT
Sbjct: 568  KARLLKDYIQNIRATYTKDFTNKDTMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCT 627

Query: 1041 LKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDMLDTS 862
            LKVENV  +PPN LEFDFLGKDSI+Y+   E +  VYKA+ +F+ GK G DDLFD LDTS
Sbjct: 628  LKVENVALVPPNKLEFDFLGKDSIRYFNTVEVELPVYKAIGQFKTGKSGGDDLFDKLDTS 687

Query: 861  KLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAIICNH 682
            KLNAHLKELMPGLTAKVFRT+NAS TLD+ML + A  G+ +EKI IYQHANKEVAIICNH
Sbjct: 688  KLNAHLKELMPGLTAKVFRTYNASITLDEMLNREARGGDAMEKIVIYQHANKEVAIICNH 747

Query: 681  QRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSPEAIE 502
            QR+VSKSH  QM RL  ++ E +  L++L+ DLARA+KGKP LKDS GK K+N++PE +E
Sbjct: 748  QRSVSKSHDVQMSRLSEKMRELQGVLDELKTDLARAKKGKPPLKDSDGKPKKNMTPEVLE 807

Query: 501  KKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMFNKSL 322
            +KI  T  +IEK ERD ++KEDLK +ALGTSKINYLDPRI+VAWCKR EVPIEK+FNKSL
Sbjct: 808  RKIAQTNTKIEKMERDMKTKEDLKTVALGTSKINYLDPRISVAWCKRQEVPIEKIFNKSL 867

Query: 321  LAKFSWAMDCDPSFRF 274
            LAKF+WAMD DPSFRF
Sbjct: 868  LAKFAWAMDVDPSFRF 883


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score =  899 bits (2322), Expect = 0.0
 Identities = 487/860 (56%), Positives = 573/860 (66%), Gaps = 33/860 (3%)
 Frame = -3

Query: 2754 LLSRGLPKKLPS--TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXD 2581
            + S G   KL +  T+ A   N        ++ +   P A     S+            +
Sbjct: 102  ITSPGANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESS--------DDE 153

Query: 2580 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2401
            KPL AR S  S  G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSMGKSNHANKE---------GGDSCSIR----RPVIEESE--------- 191

Query: 2400 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2224
                 DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+     P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASPEGPMNKSAS 246

Query: 2223 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 2101
             S KR   E  S  QSS+KK KLS   +S   KQ  VK   K                  
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2100 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1945
                    +DDDH PISQR+                                        
Sbjct: 307  TAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKKASTVVSTSLKKVNKKSKKVIRKTA 366

Query: 1944 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1771
                    P SGEGQKWTTLVHNGV+FPPPY+ HG+KMLY  +P+ LTPEQEEVATM+AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAV 426

Query: 1770 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1591
            ML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEK 486

Query: 1590 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1411
                        KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI PRDITI
Sbjct: 487  KALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITI 546

Query: 1410 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1231
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDP+N +E KYVFLAASS+LKGQS KE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNIKECKYVFLAASSTLKGQSVKE 606

Query: 1230 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 1054
            KYEKAR LKDYI GIR+AYTK FT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1053 GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 874
            GCCTLKVENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G++DLFD 
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 873  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 694
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G++ EK+A+YQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKIAEKVAVYQHANKEVAI 786

Query: 693  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 514
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  KD+ G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKDADGEPKRNLNP 846

Query: 513  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 334
            E++E+KI  T  +IEK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  ESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 333  NKSLLAKFSWAMDCDPSFRF 274
            NKSLLAKF+WAMD DPSFRF
Sbjct: 907  NKSLLAKFAWAMDVDPSFRF 926


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score =  897 bits (2317), Expect = 0.0
 Identities = 485/860 (56%), Positives = 573/860 (66%), Gaps = 33/860 (3%)
 Frame = -3

Query: 2754 LLSRGLPKKLPS--TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXD 2581
            + S G   KL +  T+ A   N        ++ +   P A     S+            +
Sbjct: 102  ITSPGANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESS--------DDE 153

Query: 2580 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2401
            KPL AR S  S +G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSKGKSNHANKE---------GGDSCSIR----RPVIEESE--------- 191

Query: 2400 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2224
                 DS+DEKPLS +  +KS+ G S+ K +DSDE KPLA+K+ QNG+  R+ P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSHDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2223 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 2101
             S KR   E  S  QSS+KK KLS   +S   KQ  VK   K                  
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSTITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2100 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1945
                    +DDD+ PISQR+                                        
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1944 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1771
                    P SGEGQKWTTLVHNGV+FPPPY+ HG+KMLY  +P+ LTPEQEEVATM+A 
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAA 426

Query: 1770 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1591
            ML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEK 486

Query: 1590 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1411
                        KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI PRDITI
Sbjct: 487  KALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITI 546

Query: 1410 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1231
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDP+N +E KYVFLAASS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAASSTLKGQSDKE 606

Query: 1230 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 1054
            KYEKAR LKDYI GIR+AYTKDFT+ KD  ++Q+AVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1053 GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 874
            GCCTLKVENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G++DLFD 
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 873  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 694
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQ ANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQRANKEVAI 786

Query: 693  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 514
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K   G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 513  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 334
            EA+E+KI  T  +IEK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 333  NKSLLAKFSWAMDCDPSFRF 274
            NKSLLAKF+WAMD DPSFRF
Sbjct: 907  NKSLLAKFAWAMDVDPSFRF 926


>ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinifera]
            gi|296082698|emb|CBI21703.3| unnamed protein product
            [Vitis vinifera]
          Length = 857

 Score =  895 bits (2314), Expect = 0.0
 Identities = 468/751 (62%), Positives = 534/751 (71%), Gaps = 15/751 (1%)
 Frame = -3

Query: 2481 KPLSARMDKGRPMAGASQTQ----KMKAMNVKPAADDSDDEK-PLSIKLNKSNSGVSSVK 2317
            KPLS R+  G P    S       +     VK   DD DD+K PLS K            
Sbjct: 119  KPLSVRLSSGLPKGKGSSNNVGLGRGGVGGVKKEEDDDDDDKIPLSSKFQLK-------- 170

Query: 2316 YYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSAEASSGQSS-VKKAKLSDASSS 2140
               SDE KPL  K+ QNG   +   S  VL          +S GQSS VKK K+S  S+ 
Sbjct: 171  ---SDEKKPLPLKVNQNGGTDKRDKSPTVLNKKRPLDGVNSSLGQSSLVKKPKISGQSAQ 227

Query: 2139 G-KAKQIPVKGAAK---DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1972
              K      K   K   DDDD +PISQRM                               
Sbjct: 228  PFKVTHATAKAEPKVEDDDDDDMPISQRMKKSGASSGNKPVPAKQKVTKVVSSTSFKKTK 287

Query: 1971 XXXXXXXXXXXXKEL-----PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLT 1807
                                P+SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY GKPVDLT
Sbjct: 288  DIKSKKMEKNSKYSKSTKVPPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLT 347

Query: 1806 PEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRX 1627
            PEQEEVATM+AVML+TDY++K+KF ENF  DW+K+LGKNHVIQ L  CDFTPIYEWH   
Sbjct: 348  PEQEEVATMFAVMLDTDYMQKEKFKENFMADWRKILGKNHVIQRLDDCDFTPIYEWHQEE 407

Query: 1626 XXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGK 1447
                                    KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Sbjct: 408  KEKKKQMSTEEKKTLKEEKLKLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGK 467

Query: 1446 LKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLA 1267
            LK+RI+P DITINIGK++ IPECPIPG+ WKEV+HDNTVTWLA+WNDPINP+EFKYVFLA
Sbjct: 468  LKRRIHPSDITINIGKNSQIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLA 527

Query: 1266 ASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTSKDLTRQQIAVATYLIDRLALRAG 1087
            ASSSLKGQSDKEKYEKARKLK+YI+ IR+ YTKDF SKD+T++QIAVATYLID+LALRAG
Sbjct: 528  ASSSLKGQSDKEKYEKARKLKNYIKDIRATYTKDFVSKDITKRQIAVATYLIDKLALRAG 587

Query: 1086 NEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRL 907
            NEKD++EADTVGCCTLKVENV P PPN L+FDFLGKDSI+Y K  E +  VYKA+E+FR+
Sbjct: 588  NEKDDDEADTVGCCTLKVENVIPEPPNSLQFDFLGKDSIRYEKTVEVELPVYKAIEQFRV 647

Query: 906  GKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIA 727
            GK G+DDLFD LDTSKLNAHLKELMPGLTAKVFRT+NAS TLD+ML K    G+V +K+ 
Sbjct: 648  GKSGSDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLNKDTKEGDVAQKVV 707

Query: 726  IYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKD 547
            +YQHANKEVAIICNHQRT+SKSH+AQM RL  +IDE K  LN L+ DLARA+KGKP LKD
Sbjct: 708  VYQHANKEVAIICNHQRTISKSHTAQMTRLTEKIDEMKGVLNGLKTDLARAKKGKPPLKD 767

Query: 546  SSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWC 367
            + GK +RNL+PEA+E+KI  T  +IEK ERDK +KEDLK +ALGTSKINYLDPRI+VAWC
Sbjct: 768  ADGK-RRNLTPEALERKIAQTNAKIEKMERDKDTKEDLKTVALGTSKINYLDPRISVAWC 826

Query: 366  KRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 274
            KR EVPIEK+FNKSLLAKF+WAMD  P FRF
Sbjct: 827  KRQEVPIEKVFNKSLLAKFAWAMDVPPDFRF 857


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score =  894 bits (2310), Expect = 0.0
 Identities = 485/860 (56%), Positives = 574/860 (66%), Gaps = 33/860 (3%)
 Frame = -3

Query: 2754 LLSRGLPKKLPS--TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXD 2581
            + S G   KL +  T+ A   N        ++ +   P A     S+            +
Sbjct: 102  ITSPGANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESS--------DDE 153

Query: 2580 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2401
            KPL AR S  S +G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSKGKSNHANKE---------GGDSCSIR----RPVIEESE--------- 191

Query: 2400 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2224
                 DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLATKVQQNGSASRDGPMNKSAS 246

Query: 2223 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 2101
               KR   E  S  QSS+KKAKLS   +S   KQ  VK   K                  
Sbjct: 247  LLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2100 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1945
                    +DDD+ PISQR+                                        
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1944 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1771
                    P SGEGQKWTTLVHNGV+F PPY+ HG+KMLY  +P+ LTPEQEEVATM+AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKXQPLTLTPEQEEVATMFAV 426

Query: 1770 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1591
            ML+TDY+ K +F ENFF DWKK+LGKNH +Q+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQMTTEEK 486

Query: 1590 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1411
                        KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PRDITI
Sbjct: 487  KALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITI 546

Query: 1410 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1231
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLA+WNDPIN +E KYVFLAASS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDPINQKECKYVFLAASSTLKGQSDKE 606

Query: 1230 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 1054
            KYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1053 GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 874
            GCCTLKVENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G  DLFD 
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGCADLFDR 726

Query: 873  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 694
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 693  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 514
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K + G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPAKGADGEPKRNLNP 846

Query: 513  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 334
            E++E+KI  T  +IEK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR+EVPIEK+F
Sbjct: 847  ESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRHEVPIEKIF 906

Query: 333  NKSLLAKFSWAMDCDPSFRF 274
            NKSLLAKF+W+MD DPSFRF
Sbjct: 907  NKSLLAKFAWSMDVDPSFRF 926


>dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score =  888 bits (2294), Expect = 0.0
 Identities = 481/853 (56%), Positives = 569/853 (66%), Gaps = 33/853 (3%)
 Frame = -3

Query: 2754 LLSRGLPKKLPS--TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXD 2581
            + S G   KL +  T+ A   N        ++ +   P A     S+            +
Sbjct: 102  ITSPGANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPPAKANSNSESS--------DDE 153

Query: 2580 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2401
            KPL AR S  S +G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSKGKSNHANKE---------GGDSCSIR----RPVVEESE--------- 191

Query: 2400 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2224
                 DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2223 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 2101
             S KR   E  S  QSS+KK KLS   +S   KQ  VK   K                  
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2100 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1945
                    +DDD+ PISQR+                                        
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1944 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1771
                    P SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEEVATM+AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPLTLTPEQEEVATMFAV 426

Query: 1770 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1591
            ML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEREKKKQMTTEEK 486

Query: 1590 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1411
                        KYMWAI+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI+PRDITI
Sbjct: 487  KALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIHPRDITI 546

Query: 1410 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1231
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDP+N +E KYVFLA SS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLKGQSDKE 606

Query: 1230 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 1054
            KYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1053 GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 874
            GCCTL+VENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G++DLFD 
Sbjct: 667  GCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 873  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 694
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 693  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 514
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K   G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 513  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 334
            EA+E+KI  T  +IEK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 333  NKSLLAKFSWAMD 295
            NKSLLAKF+WAM+
Sbjct: 907  NKSLLAKFAWAMN 919


>ref|XP_006364175.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Solanum
            tuberosum]
          Length = 905

 Score =  880 bits (2275), Expect = 0.0
 Identities = 472/826 (57%), Positives = 561/826 (67%), Gaps = 5/826 (0%)
 Frame = -3

Query: 2736 PKKLPSTNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXDKPLSARCS 2557
            P   PS++  + A + +++  +  ++++  +  K E +D+           DKPLSAR  
Sbjct: 123  PNSRPSSSAGNQAKNVNQQSNIAPKESKQAIEPKSEPNDEA-----EDSEDDKPLSARVP 177

Query: 2556 VLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNVKPAADDSD 2377
                + NS  AN  +             S  + K RP                P  +DSD
Sbjct: 178  SGLSKSNSIHANNVLGT-----------STSVQKSRP----------------PKKEDSD 210

Query: 2376 DEKPLSIKLN-KSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLGSSVKRPSA 2200
            DE PL+ +   KS++G S+ K+  S+E KP   K+ QNG      PS  VL    KRP  
Sbjct: 211  DEIPLASRFQMKSSAGASTSKFSSSEEVKP---KIRQNGL-----PSATVLS---KRPPG 259

Query: 2199 EASSG-QSSVKKAKLSDASSSGKAKQIPVKGAAK--DDDDHIPISQRMXXXXXXXXXXXX 2029
            E S   +  +K                 VK   K  DDDD +P+SQR+            
Sbjct: 260  EVSLLLRLQLKSLDFLMHLHLFLVSNXSVKTEKKTEDDDDEVPLSQRIKKAVASASASAS 319

Query: 2028 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKEL-PNSGEGQKWTTLVHNGVIFPPPYQS 1852
                                            +L P+SG+GQKWTTL HNGVIFPPPY+ 
Sbjct: 320  KVSSVKKATKVVSSSMKKTKKKLKKPKYSKSSKLQPSSGDGQKWTTLEHNGVIFPPPYKP 379

Query: 1851 HGIKMLYNGKPVDLTPEQEEVATMYAVMLETDYVKKDKFNENFFGDWKKLLGKNHVIQDL 1672
            HG+KMLY GKPVDLTPEQEEVATMYAVML+T+Y+ K +F ENF  DW+K+LGKNHVIQ L
Sbjct: 380  HGVKMLYKGKPVDLTPEQEEVATMYAVMLDTEYLTKQQFKENFMNDWRKILGKNHVIQKL 439

Query: 1671 SKCDFTPIYEWHLRXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEP 1492
             +C+FTPIYEWH                           KYMWAI+DGVKEKVGNFRVEP
Sbjct: 440  EECNFTPIYEWHQSEKEKKKQMSSEEKKALREEKLKQEEKYMWAIVDGVKEKVGNFRVEP 499

Query: 1491 PGLFRGRGEHPKMGKLKKRIYPRDITINIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYW 1312
            PGLFRGRGEHPKMGKLK+RI P DITINIGK  P+PECPIPGQRWKEVRHDNTVTWLA+W
Sbjct: 500  PGLFRGRGEHPKMGKLKRRIRPNDITINIGKGVPVPECPIPGQRWKEVRHDNTVTWLAFW 559

Query: 1311 NDPINPREFKYVFLAASSSLKGQSDKEKYEKARKLKDYIEGIRSAYTKDFTSKDLTRQQI 1132
            NDPINPREFKYVFLAASSSLKGQSDKEKYEKAR+LKDYIEGIRSAYTKDFTSKD  ++QI
Sbjct: 560  NDPINPREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIEGIRSAYTKDFTSKDPVKRQI 619

Query: 1131 AVATYLIDRLALRAGNEKDEEEADTVGCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQF 952
            AVATYLID+LALRAGNEKD++EADTVGCCTLKVENV+P+PPNIL+FDFLGKDSI+Y  + 
Sbjct: 620  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEV 679

Query: 951  EADPRVYKAVERFRLGKKGNDDLFDMLDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDM 772
                 V+KA+++FR GKKG DDLFD LDTSKLNAHLKELMPGLTAKVFRT+NASFTL+  
Sbjct: 680  AVYEPVFKAIQQFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASFTLEQQ 739

Query: 771  LAKGAGSGEVLEKIAIYQHANKEVAIICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLE 592
            L K    GE+ +K+A+Y  ANKEVAIICNHQRTVSKSHS Q+ RL  +IDE KA L + +
Sbjct: 740  LTKLTQGGELADKVAVYNVANKEVAIICNHQRTVSKSHSVQISRLNEKIDELKAILEEFK 799

Query: 591  KDLARARKGKPLLKDSSGKQKRNLSPEAIEKKIISTRNRIEKFERDKQSKEDLKEIALGT 412
             DLARA+KGKP +K + GK KRNL+PEA++KKI  T  +I+  ER  ++KE+LK +ALGT
Sbjct: 800  VDLARAKKGKPPVKGADGKAKRNLTPEALQKKIDQTNVKIDNIERQIETKEELKTVALGT 859

Query: 411  SKINYLDPRITVAWCKRNEVPIEKMFNKSLLAKFSWAMDCDPSFRF 274
            SKINYLDPRITVAWCKR+EVPIEKMFNKSLLAKF+WAMD +PSF F
Sbjct: 860  SKINYLDPRITVAWCKRHEVPIEKMFNKSLLAKFAWAMDVEPSFTF 905


>dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]
          Length = 920

 Score =  880 bits (2273), Expect = 0.0
 Identities = 479/853 (56%), Positives = 565/853 (66%), Gaps = 33/853 (3%)
 Frame = -3

Query: 2754 LLSRGLPKKLPS--TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXD 2581
            + S G   KL +  T+ A   N        ++ +   P A     S+            +
Sbjct: 102  ITSPGANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESS--------DDE 153

Query: 2580 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2401
            KPL AR S  S +G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSKGKSNHANKE---------GGDSCSIR----RPVIEESE--------- 191

Query: 2400 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2224
                 DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+  NG+  R+ P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDGPMNKSAS 246

Query: 2223 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 2101
             S KR   E  S  QSS+KK KLS   +S   KQ  VK   K                  
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2100 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1945
                    +DDD+ PISQR+                                        
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1944 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1771
                    P SGEGQKWTTLVHNGVIFPPPY+ HG+KMLY  +P+ LTPEQEEVATM+AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAV 426

Query: 1770 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1591
            ML+TDY+ K +F ENFF DWKK+LGKNH IQ+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEK 486

Query: 1590 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1411
                        KYMW I+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI PRDITI
Sbjct: 487  KALKEERLQQEEKYMWVIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIRPRDITI 546

Query: 1410 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1231
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDPIN +E KYVFL ASS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKERKYVFLGASSTLKGQSDKE 606

Query: 1230 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 1054
            KYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1053 GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 874
            GCCTLKVENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G+ DLFD 
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSADLFDR 726

Query: 873  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 694
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 693  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 514
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K + G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGADGEPKRNLNP 846

Query: 513  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 334
            EA+E+KI  T  +IEK E DK++KEDLK +AL TSKI+YL PRITVAWCKR+EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMEGDKKTKEDLKAVALSTSKISYLGPRITVAWCKRHEVPIEKMF 906

Query: 333  NKSLLAKFSWAMD 295
            NKSLLAKF+WAM+
Sbjct: 907  NKSLLAKFAWAMN 919


>dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]
          Length = 920

 Score =  878 bits (2268), Expect = 0.0
 Identities = 478/853 (56%), Positives = 567/853 (66%), Gaps = 33/853 (3%)
 Frame = -3

Query: 2754 LLSRGLPKKLPS--TNGASSANDKSKKDVLVKEQNRAPVAVKEEKSDKRMCXXXXXXXXD 2581
            + S G   KL +  T+ A   N        ++ +   P A     S+            +
Sbjct: 102  ITSPGANSKLSASATSTAKQQNHHKSSAAFIEPKPSVPPAKANSNSESS--------DDE 153

Query: 2580 KPLSARCSVLSQRGNSTVANVEVKPXXXXXXXDKPLSARMDKGRPMAGASQTQKMKAMNV 2401
            KPL AR S  S +G S  AN E              S R    RP+   S+         
Sbjct: 154  KPLIARTSGCSSKGKSNHANKE---------GGDSCSIR----RPVVEESE--------- 191

Query: 2400 KPAADDSDDEKPLSIKL-NKSNSGVSSVKYYDSDEHKPLASKLLQNGTIKRNTPSMKVLG 2224
                 DS+DEKPLS +  +KS+ G S+ K YDSDE KPLA+K+ QNG+  R+ P  K   
Sbjct: 192  -----DSEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSAS 246

Query: 2223 SSVKRPSAEASS-GQSSVKKAKLSDASSSGKAKQIPVKGAAK------------------ 2101
             S KR   E  S  QSS+KK KLS   +S   KQ  VK   K                  
Sbjct: 247  LSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQ 306

Query: 2100 --------DDDDHIPISQRMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1945
                    +DDD+ PISQR+                                        
Sbjct: 307  TAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTA 366

Query: 1944 XXXKEL--PNSGEGQKWTTLVHNGVIFPPPYQSHGIKMLYNGKPVDLTPEQEEVATMYAV 1771
                    P SGEGQKWTTLVHNGV+F PPY+ HG+KMLY  +P+ LTPEQEEVATM+AV
Sbjct: 367  YTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKQQPLTLTPEQEEVATMFAV 426

Query: 1770 MLETDYVKKDKFNENFFGDWKKLLGKNHVIQDLSKCDFTPIYEWHLRXXXXXXXXXXXXX 1591
            ML+TDY+ K +F ENFF DWKK+LGKNH +Q+L  CDF PIYEWH +             
Sbjct: 427  MLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQMTTEEK 486

Query: 1590 XXXXXXXXXXXXKYMWAILDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIYPRDITI 1411
                        KYM AI+DGVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI+PRDITI
Sbjct: 487  KALKEERLQQEEKYMRAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIHPRDITI 546

Query: 1410 NIGKDAPIPECPIPGQRWKEVRHDNTVTWLAYWNDPINPREFKYVFLAASSSLKGQSDKE 1231
            NIGKDAPIPECPIPG+RWKEVR+DNTVTWLAYWNDP+N +E KYVFLA SS+LKGQSDKE
Sbjct: 547  NIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLKGQSDKE 606

Query: 1230 KYEKARKLKDYIEGIRSAYTKDFTS-KDLTRQQIAVATYLIDRLALRAGNEKDEEEADTV 1054
            KYEKAR LKDYI GIR+AYTKDFT+ KD  ++QIAVATYLID+LALRAGNEKD++EADTV
Sbjct: 607  KYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTV 666

Query: 1053 GCCTLKVENVKPIPPNILEFDFLGKDSIKYYKQFEADPRVYKAVERFRLGKKGNDDLFDM 874
            GCCTLKVENV+P+PPNIL+ DF+GKDSI+Y  + + +P V+KA+++FR GK+G++DLFD 
Sbjct: 667  GCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGSEDLFDR 726

Query: 873  LDTSKLNAHLKELMPGLTAKVFRTFNASFTLDDMLAKGAGSGEVLEKIAIYQHANKEVAI 694
            LDTSKLNAHLKELMPGLTAKVFRT+NAS TLDDML+K    G+V EK+ +YQHANKEVAI
Sbjct: 727  LDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHANKEVAI 786

Query: 693  ICNHQRTVSKSHSAQMERLQTRIDEAKAELNDLEKDLARARKGKPLLKDSSGKQKRNLSP 514
            ICNHQRTVSKSHSAQM RL  +IDE K  L +L+ DL+RA+KGKP  K   G+ KRNL+P
Sbjct: 787  ICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEPKRNLNP 846

Query: 513  EAIEKKIISTRNRIEKFERDKQSKEDLKEIALGTSKINYLDPRITVAWCKRNEVPIEKMF 334
            EA+E+KI  T  +IEK ERDK++KEDLK +AL TSKI+YLDPRITVAWCKR EVPIEKMF
Sbjct: 847  EALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEVPIEKMF 906

Query: 333  NKSLLAKFSWAMD 295
            NKSLLAKF+WAM+
Sbjct: 907  NKSLLAKFAWAMN 919