BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Acanthopanax24_contig00013134
         (1532 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_017257659.1| PREDICTED: bifunctional dihydrofolate reduct...   947   0.0  
ref|XP_017215083.1| PREDICTED: bifunctional dihydrofolate reduct...   929   0.0  
sp|P45350.1|DRTS_DAUCA RecName: Full=Bifunctional dihydrofolate ...   910   0.0  
emb|CAA05895.1| dihydrofolate reductase-thymidylate synthetase p...   910   0.0  
gb|KZN11004.1| hypothetical protein DCAR_003660 [Daucus carota s...   907   0.0  
ref|XP_021662680.1| bifunctional dihydrofolate reductase-thymidy...   905   0.0  
ref|XP_021658747.1| bifunctional dihydrofolate reductase-thymidy...   905   0.0  
ref|XP_002280254.1| PREDICTED: bifunctional dihydrofolate reduct...   895   0.0  
gb|KZM89650.1| hypothetical protein DCAR_022987 [Daucus carota s...   892   0.0  
ref|XP_021628142.1| bifunctional dihydrofolate reductase-thymidy...   891   0.0  
gb|OMO75612.1| Thymidylate synthase [Corchorus olitorius]             890   0.0  
gb|OMO74316.1| Thymidylate synthase [Corchorus capsularis]            890   0.0  
ref|XP_021285499.1| bifunctional dihydrofolate reductase-thymidy...   889   0.0  
ref|XP_007042127.2| PREDICTED: bifunctional dihydrofolate reduct...   889   0.0  
gb|EOX97956.1| Thymidylate synthase 1 isoform 1 [Theobroma cacao...   888   0.0  
ref|XP_011037491.1| PREDICTED: bifunctional dihydrofolate reduct...   887   0.0  
ref|XP_010254750.1| PREDICTED: putative bifunctional dihydrofola...   887   0.0  
ref|XP_010254749.1| PREDICTED: putative bifunctional dihydrofola...   887   0.0  
ref|XP_010254751.1| PREDICTED: putative bifunctional dihydrofola...   886   0.0  
ref|XP_020533467.1| bifunctional dihydrofolate reductase-thymidy...   885   0.0  

>ref|XP_017257659.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
 ref|XP_017257740.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
          Length = 576

 Score =  947 bits (2447), Expect = 0.0
 Identities = 451/510 (88%), Positives = 483/510 (94%), Gaps = 2/510 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MA + L +  NGSGIT  DPQRTYQVVVAATQNMGIGKDGK+PWRLPSD+KFFKDVTMTT
Sbjct: 50   MASEALANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFFKDVTMTT 109

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            SDP+K+NAVIMGRKTWESIP++HRPLP RLNVVLTRSGSFDIAT ENVVICGSMISALEL
Sbjct: 110  SDPLKRNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGSMISALEL 169

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LA SPYCVS+EKVFVIGGGQIYREALNAPGCDA+HIT+IEE IECDTFIP LDESVFQPW
Sbjct: 170  LAGSPYCVSVEKVFVIGGGQIYREALNAPGCDAVHITEIEEHIECDTFIPLLDESVFQPW 229

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 722
            YSSFPLVEN IRYCFTTYVRVR+S  E   QTNGLSSD+ SDSG FEIQ FSFLPK +FE
Sbjct: 230  YSSFPLVENKIRYCFTTYVRVRNSVAELTSQTNGLSSDSKSDSGNFEIQNFSFLPKTVFE 289

Query: 723  KHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 902
            KHEEY+YL +VENIISNGV+K+DRTRTGT+SIFGCQMRFNLRKSFPLLTTKKVFWRGVVE
Sbjct: 290  KHEEYLYLGLVENIISNGVTKNDRTRTGTVSIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 349

Query: 903  ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1082
            ELLWFISGSTNAK+L+EKG++IWEGNGSR+YLDSIGL DREEGDLGPIYGFQWRHFGARY
Sbjct: 350  ELLWFISGSTNAKILKEKGVNIWEGNGSREYLDSIGLTDREEGDLGPIYGFQWRHFGARY 409

Query: 1083 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1262
            TDMHADY+GQGFDQLLDV+SKIKNNPDDRRIILSAWNPSDL+LMALPPCHMFAQFYVA G
Sbjct: 410  TDMHADYSGQGFDQLLDVISKIKNNPDDRRIILSAWNPSDLRLMALPPCHMFAQFYVANG 469

Query: 1263 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1442
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+H+IGDAHVYC HVRPL+
Sbjct: 470  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHSIGDAHVYCNHVRPLR 529

Query: 1443 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            +QLQKLPKPFP+LKINSEKRDIDSF AADF
Sbjct: 530  DQLQKLPKPFPVLKINSEKRDIDSFEAADF 559


>ref|XP_017215083.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
 ref|XP_017215084.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
 ref|XP_017215085.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
          Length = 527

 Score =  929 bits (2400), Expect = 0.0
 Identities = 445/510 (87%), Positives = 478/510 (93%), Gaps = 2/510 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MA +TL +  NGS IT ++PQRTYQVVVAATQNMGIGKDG +PW LPSDLKFFKDVTMTT
Sbjct: 1    MASETLTNPTNGSVITSSNPQRTYQVVVAATQNMGIGKDGSLPWSLPSDLKFFKDVTMTT 60

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            SDP+K+NAVIMGRKTWESIPL+HRPLP R NVVLTRSGSFDIATAENVVICGS++SALEL
Sbjct: 61   SDPLKRNAVIMGRKTWESIPLQHRPLPGRFNVVLTRSGSFDIATAENVVICGSLLSALEL 120

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LA SPYCVSIEKVFVIGGGQIYREALNAPGCDA+HIT+I + IECDTFIP LDESVFQPW
Sbjct: 121  LAESPYCVSIEKVFVIGGGQIYREALNAPGCDAVHITEIGKHIECDTFIPALDESVFQPW 180

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 722
            YSSFP+VENNIRYCFTTYVRVR+S VE   + NGL SD NSDSGKFE+Q+FSFLPK +FE
Sbjct: 181  YSSFPVVENNIRYCFTTYVRVRNSGVELASEANGLLSDGNSDSGKFEVQRFSFLPKPVFE 240

Query: 723  KHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 902
            KH+EY+YLR+VENII NGV K+DRTRTGT+S+FGCQMRFNLRKSFPLLTTKKVFWRGVVE
Sbjct: 241  KHQEYLYLRLVENIILNGVEKNDRTRTGTVSMFGCQMRFNLRKSFPLLTTKKVFWRGVVE 300

Query: 903  ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1082
            ELLWFISGSTNAKVL+EKGI+IWEGNGSRDYLDSIGL  REEGDLGPIYGFQWRHFGARY
Sbjct: 301  ELLWFISGSTNAKVLKEKGINIWEGNGSRDYLDSIGLTHREEGDLGPIYGFQWRHFGARY 360

Query: 1083 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1262
            TDMHADYTGQGFDQL DV+SKIK NPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA G
Sbjct: 361  TDMHADYTGQGFDQLQDVISKIKENPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 420

Query: 1263 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1442
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+HTIGDAH+Y  HVRPLQ
Sbjct: 421  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHTIGDAHIYLNHVRPLQ 480

Query: 1443 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            +QLQKLPKPFP+LKINSEKR+IDSF AADF
Sbjct: 481  DQLQKLPKPFPVLKINSEKRNIDSFEAADF 510


>sp|P45350.1|DRTS_DAUCA RecName: Full=Bifunctional dihydrofolate reductase-thymidylate
            synthase; Short=DHFR-TS; Includes: RecName:
            Full=Dihydrofolate reductase; Includes: RecName:
            Full=Thymidylate synthase
 emb|CAA78954.1| dihydrofolate reductase-thymidylate synthetase [Daucus carota]
          Length = 528

 Score =  910 bits (2351), Expect = 0.0
 Identities = 437/511 (85%), Positives = 472/511 (92%), Gaps = 3/511 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MA + L +  NGSGIT  DPQRTYQVVVAATQNMGIGKDGK+PWRLPSD+KFFKDVTMTT
Sbjct: 1    MASELLANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFFKDVTMTT 60

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            SDP+K+NAVIMGRKTWESIP++HRPLP RLNVVLTRSGSFDIAT ENVVICGSMISALEL
Sbjct: 61   SDPLKRNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGSMISALEL 120

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LA SPYCVS+EKVFVIGGGQIYREALNAPGCDA+HIT+IEE IECDTFIP LDESVFQPW
Sbjct: 121  LAGSPYCVSVEKVFVIGGGQIYREALNAPGCDAVHITEIEEHIECDTFIPLLDESVFQPW 180

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 722
            YSSFPLVEN IRYCFTTYVRVR+S  E   QTNG SSD+ SDSG FEIQ FSFLPK +FE
Sbjct: 181  YSSFPLVENKIRYCFTTYVRVRNSVAELTSQTNGCSSDSKSDSGNFEIQNFSFLPKTVFE 240

Query: 723  KHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 902
            KHEEY+YL +VENIISNGV+K+DRTRTGT+SIFGCQMRFNLRKSFPLLTTKKVFWRGVVE
Sbjct: 241  KHEEYLYLGLVENIISNGVTKNDRTRTGTVSIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 300

Query: 903  ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1082
            ELLWFISGSTNAK+L+EKG++IWEGNGSR+YLDSIGL DREEGDLGPIYGFQWRHFGARY
Sbjct: 301  ELLWFISGSTNAKILKEKGVNIWEGNGSREYLDSIGLTDREEGDLGPIYGFQWRHFGARY 360

Query: 1083 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1262
            TDMHADY+GQGFDQLLDV+SKIKNNPDDRRII SAWNPSDL+LMALPPCHMFAQFYVA G
Sbjct: 361  TDMHADYSGQGFDQLLDVISKIKNNPDDRRIIQSAWNPSDLRLMALPPCHMFAQFYVANG 420

Query: 1263 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1442
            ELSCQMYQRSADMGLGVPFNIA+YALLTCMIAHVCDLVPGDF+H+IGDAHVY  H+  L 
Sbjct: 421  ELSCQMYQRSADMGLGVPFNIAAYALLTCMIAHVCDLVPGDFVHSIGDAHVYSNHLSDLF 480

Query: 1443 E-QLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            E   + LPK FP+LKINS ++DIDSF AADF
Sbjct: 481  ETSFRMLPKTFPVLKINSGEKDIDSFEAADF 511


>emb|CAA05895.1| dihydrofolate reductase-thymidylate synthetase precursor [Daucus
            carota]
          Length = 577

 Score =  910 bits (2351), Expect = 0.0
 Identities = 437/511 (85%), Positives = 472/511 (92%), Gaps = 3/511 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MA + L +  NGSGIT  DPQRTYQVVVAATQNMGIGKDGK+PWRLPSD+KFFKDVTMTT
Sbjct: 50   MASERLANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFFKDVTMTT 109

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            SDP+K+NAVIMGRKTWESIP++HRPLP RLNVVLTRSGSFDIAT ENVVICGSMISALEL
Sbjct: 110  SDPLKRNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGSMISALEL 169

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LA SPYCVS+EKVFVIGGGQIYREALNAPGCDA+HIT+IEE IECDTFIP LDESVFQPW
Sbjct: 170  LAGSPYCVSVEKVFVIGGGQIYREALNAPGCDAVHITEIEEHIECDTFIPLLDESVFQPW 229

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 722
            YSSFPLVEN IRYCFTTYVRVR+S  E   QTNG SSD+ SDSG FEIQ FSFLPK +FE
Sbjct: 230  YSSFPLVENKIRYCFTTYVRVRNSVAELTSQTNGCSSDSKSDSGNFEIQNFSFLPKTVFE 289

Query: 723  KHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 902
            KHEEY+YL +VENIISNGV+K+DRTRTGT+SIFGCQMRFNLRKSFPLLTTKKVFWRGVVE
Sbjct: 290  KHEEYLYLGLVENIISNGVTKNDRTRTGTVSIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 349

Query: 903  ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1082
            ELLWFISGSTNAK+L+EKG++IWEGNGSR+YLDSIGL DREEGDLGPIYGFQWRHFGARY
Sbjct: 350  ELLWFISGSTNAKILKEKGVNIWEGNGSREYLDSIGLTDREEGDLGPIYGFQWRHFGARY 409

Query: 1083 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1262
            TDMHADY+GQGFDQLLDV+SKIKNNPDDRRII SAWNPSDL+LMALPPCHMFAQFYVA G
Sbjct: 410  TDMHADYSGQGFDQLLDVISKIKNNPDDRRIIQSAWNPSDLRLMALPPCHMFAQFYVANG 469

Query: 1263 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1442
            ELSCQMYQRSADMGLGVPFNIA+YALLTCMIAHVCDLVPGDF+H+IGDAHVY  H+  L 
Sbjct: 470  ELSCQMYQRSADMGLGVPFNIAAYALLTCMIAHVCDLVPGDFVHSIGDAHVYSNHLSDLF 529

Query: 1443 E-QLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            E   + LPK FP+LKINS ++DIDSF AADF
Sbjct: 530  ETSFRMLPKTFPVLKINSGEKDIDSFEAADF 560


>gb|KZN11004.1| hypothetical protein DCAR_003660 [Daucus carota subsp. sativus]
          Length = 560

 Score =  907 bits (2345), Expect = 0.0
 Identities = 436/510 (85%), Positives = 468/510 (91%), Gaps = 2/510 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MA + L +  NGSGIT  DPQRTYQVVVAATQNMGIGKDGK+PWRLPSD+KFFKDVTMTT
Sbjct: 1    MASEALANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFFKDVTMTT 60

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            SDP+K+NAVIMGRKTWESIP++HRPLP RLNVVLTRSGSFDIAT ENVVICGSMISALEL
Sbjct: 61   SDPLKRNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGSMISALEL 120

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LA SPYCVS+EKVFVIGGGQIYREALNAPGCDA+HIT+IEE IECDTFIP LDESVFQPW
Sbjct: 121  LAGSPYCVSVEKVFVIGGGQIYREALNAPGCDAVHITEIEEHIECDTFIPLLDESVFQPW 180

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 722
            YSSFPLVEN IRYCFTTYVRVR+S  E   QTNGLSSD+ SDSG FEIQ FSFLPK +FE
Sbjct: 181  YSSFPLVENKIRYCFTTYVRVRNSVAELTSQTNGLSSDSKSDSGNFEIQNFSFLPKTVFE 240

Query: 723  KHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 902
            KHEEY+YL +VENIISNGV+K+DRTRTGT+SIFGCQ               KVFWRGVVE
Sbjct: 241  KHEEYLYLGLVENIISNGVTKNDRTRTGTVSIFGCQ---------------KVFWRGVVE 285

Query: 903  ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1082
            ELLWFISGSTNAK+L+EKG++IWEGNGSR+YLDSIGL DREEGDLGPIYGFQWRHFGARY
Sbjct: 286  ELLWFISGSTNAKILKEKGVNIWEGNGSREYLDSIGLTDREEGDLGPIYGFQWRHFGARY 345

Query: 1083 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1262
            TDMHADY+GQGFDQLLDV+SKIKNNPDDRRIILSAWNPSDL+LMALPPCHMFAQFYVA G
Sbjct: 346  TDMHADYSGQGFDQLLDVISKIKNNPDDRRIILSAWNPSDLRLMALPPCHMFAQFYVANG 405

Query: 1263 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1442
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+H+IGDAHVYC HVRPL+
Sbjct: 406  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHSIGDAHVYCNHVRPLR 465

Query: 1443 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            +QLQKLPKPFP+LKINSEKRDIDSF AADF
Sbjct: 466  DQLQKLPKPFPVLKINSEKRDIDSFEAADF 495


>ref|XP_021662680.1| bifunctional dihydrofolate reductase-thymidylate synthase 1-like
            [Hevea brasiliensis]
          Length = 550

 Score =  905 bits (2338), Expect = 0.0
 Identities = 432/511 (84%), Positives = 471/511 (92%), Gaps = 2/511 (0%)
 Frame = +3

Query: 6    LMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMT 185
            +MAGD+  ++ NG+      PQRTYQVVVAAT +MGIGKDGK+PWRLPSDLKFFKDVTMT
Sbjct: 23   IMAGDSKANLSNGNANIQPAPQRTYQVVVAATGDMGIGKDGKLPWRLPSDLKFFKDVTMT 82

Query: 186  TSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALE 365
            TSD  KKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVV+CGS+ SALE
Sbjct: 83   TSDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGSLSSALE 142

Query: 366  LLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQP 545
            LLAASPYC+SIEK +VIGGGQI REALNAPGCDAIHIT+IE  I+CDTFIP +D SVFQP
Sbjct: 143  LLAASPYCLSIEKAYVIGGGQILREALNAPGCDAIHITEIETNIDCDTFIPTIDSSVFQP 202

Query: 546  WYSSFPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIF 719
            WYSSFP+VENNIRYCF TYVRVRS+AVE   Q NGLSSD  S++ KFE++KFSFLPK +F
Sbjct: 203  WYSSFPMVENNIRYCFATYVRVRSTAVESNGQNNGLSSDVGSENSKFEVKKFSFLPKMVF 262

Query: 720  EKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVV 899
            E+HEE+ YLR+V++IIS+G+ KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGVV
Sbjct: 263  ERHEEFFYLRLVQDIISDGILKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVV 322

Query: 900  EELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGAR 1079
            EELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGAR
Sbjct: 323  EELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQWRHFGAR 382

Query: 1080 YTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAK 1259
            Y+DMHADYTGQGFDQLLDV+ KIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 
Sbjct: 383  YSDMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAH 442

Query: 1260 GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPL 1439
            GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVC+LVPGDF+H  GDAHVYCTHVRPL
Sbjct: 443  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLVPGDFVHVFGDAHVYCTHVRPL 502

Query: 1440 QEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            QEQLQKLPKPFPILKIN +K++IDSFVAADF
Sbjct: 503  QEQLQKLPKPFPILKINPDKKNIDSFVAADF 533


>ref|XP_021658747.1| bifunctional dihydrofolate reductase-thymidylate synthase-like [Hevea
            brasiliensis]
          Length = 550

 Score =  905 bits (2338), Expect = 0.0
 Identities = 432/511 (84%), Positives = 471/511 (92%), Gaps = 2/511 (0%)
 Frame = +3

Query: 6    LMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMT 185
            +MAGD+  ++ NG+      PQRTYQVVVAAT +MGIGKDGK+PWRLPSDLKFFKDVTMT
Sbjct: 23   IMAGDSKANLSNGNANIQPAPQRTYQVVVAATGDMGIGKDGKLPWRLPSDLKFFKDVTMT 82

Query: 186  TSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALE 365
            TSD  KKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVV+CGS+ SALE
Sbjct: 83   TSDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGSLSSALE 142

Query: 366  LLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQP 545
            LLAASPYC+SIEK +VIGGGQI REALNAPGCDAIHIT+IE  I+CDTFIP +D SVFQP
Sbjct: 143  LLAASPYCLSIEKAYVIGGGQILREALNAPGCDAIHITEIEANIDCDTFIPTIDSSVFQP 202

Query: 546  WYSSFPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIF 719
            WYSSFP+VENNIRYCF TYVRVRS+AVE   Q NGLS+D  S++ KFE++KFSFLPK +F
Sbjct: 203  WYSSFPMVENNIRYCFATYVRVRSTAVESNGQNNGLSADVGSENSKFEVKKFSFLPKMVF 262

Query: 720  EKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVV 899
            E+HEE+ YLR+V++IIS+G+ KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGVV
Sbjct: 263  ERHEEFFYLRLVQDIISDGILKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVV 322

Query: 900  EELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGAR 1079
            EELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGAR
Sbjct: 323  EELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQWRHFGAR 382

Query: 1080 YTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAK 1259
            Y+DMHADYTGQGFDQLLDV+ KIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 
Sbjct: 383  YSDMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAH 442

Query: 1260 GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPL 1439
            GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVC+LVPGDF+H  GDAHVYCTHVRPL
Sbjct: 443  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLVPGDFVHVFGDAHVYCTHVRPL 502

Query: 1440 QEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            QEQLQKLPKPFPILKIN EK++IDSFVAADF
Sbjct: 503  QEQLQKLPKPFPILKINPEKKNIDSFVAADF 533


>ref|XP_002280254.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X1 [Vitis vinifera]
 ref|XP_010645204.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X1 [Vitis vinifera]
          Length = 524

 Score =  895 bits (2313), Expect = 0.0
 Identities = 431/508 (84%), Positives = 466/508 (91%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MA DT++S+PNG+     DPQRTYQVVVAAT++MGIGKDGK+PWRLPSD+K FKD+TMT 
Sbjct: 1    MASDTVVSLPNGNANIQPDPQRTYQVVVAATRDMGIGKDGKLPWRLPSDMKIFKDITMTV 60

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            +D VKKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVVICGSM SALEL
Sbjct: 61   ADTVKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMASALEL 120

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LAASPYC+SIEKVFVIGGGQI REALNAPGCDAIHIT+IE   ECDTFIP +D  VFQPW
Sbjct: 121  LAASPYCLSIEKVFVIGGGQILREALNAPGCDAIHITEIETSFECDTFIPAIDSLVFQPW 180

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVEPQTNGLSSDTNSDSGKFEIQKFSFLPKKIFEKH 728
            YSSFPLVENNIRY F TYVRVRSSA E Q    + D+  +S KFE++KFSFLPK IFE+H
Sbjct: 181  YSSFPLVENNIRYSFMTYVRVRSSADESQIQN-NGDSGLESIKFEVKKFSFLPKMIFERH 239

Query: 729  EEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVEEL 908
            EEY+YLR+VE+IISNGV +DDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGVVEEL
Sbjct: 240  EEYIYLRLVEDIISNGVQRDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVVEEL 299

Query: 909  LWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARYTD 1088
            LWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGPIYGFQWRHFGA Y D
Sbjct: 300  LWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLADREEGDLGPIYGFQWRHFGASYID 359

Query: 1089 MHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKGEL 1268
            MHADYTGQGFDQLLDV++KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYV+ GEL
Sbjct: 360  MHADYTGQGFDQLLDVINKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVSHGEL 419

Query: 1269 SCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQEQ 1448
            SCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIH IGD+HVY TH+RPLQEQ
Sbjct: 420  SCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHVIGDSHVYLTHIRPLQEQ 479

Query: 1449 LQKLPKPFPILKINSEKRDIDSFVAADF 1532
            LQKLPKPFPILKIN +K++IDSFVAADF
Sbjct: 480  LQKLPKPFPILKINPQKKNIDSFVAADF 507


>gb|KZM89650.1| hypothetical protein DCAR_022987 [Daucus carota subsp. sativus]
          Length = 518

 Score =  892 bits (2305), Expect = 0.0
 Identities = 430/510 (84%), Positives = 466/510 (91%), Gaps = 2/510 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MA +TL +  NGS IT ++PQRTYQVVVAATQNMGIGKDG +PW LPSDLKFFKDVTMTT
Sbjct: 1    MASETLTNPTNGSVITSSNPQRTYQVVVAATQNMGIGKDGSLPWSLPSDLKFFKDVTMTT 60

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            SDP+K+NAVIMGRKTWESIPL+HRPLP R NVVLTRSGSFDIATAENVVICGS++SALEL
Sbjct: 61   SDPLKRNAVIMGRKTWESIPLQHRPLPGRFNVVLTRSGSFDIATAENVVICGSLLSALEL 120

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LA SPYCVSIEKVFVIGGGQIYREALNAPGCDA+HIT+I + IECDTFIP LDESVFQPW
Sbjct: 121  LAESPYCVSIEKVFVIGGGQIYREALNAPGCDAVHITEIGKHIECDTFIPALDESVFQPW 180

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 722
            YSSFP+VENNIRYCFTTYVRVR+S VE   + NGL SD NSDSGKFE+Q+FSFLPK +FE
Sbjct: 181  YSSFPVVENNIRYCFTTYVRVRNSGVELASEANGLLSDGNSDSGKFEVQRFSFLPKPVFE 240

Query: 723  KHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 902
            KH+EY+YLR+VENII NGV K+DRTRTGT+S+FGCQ+          +  +KVFWRGVVE
Sbjct: 241  KHQEYLYLRLVENIILNGVEKNDRTRTGTVSMFGCQL---------FVIGQKVFWRGVVE 291

Query: 903  ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1082
            ELLWFISGSTNAKVL+EKGI+IWEGNGSRDYLDSIGL  REEGDLGPIYGFQWRHFGARY
Sbjct: 292  ELLWFISGSTNAKVLKEKGINIWEGNGSRDYLDSIGLTHREEGDLGPIYGFQWRHFGARY 351

Query: 1083 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1262
            TDMHADYTGQGFDQL DV+SKIK NPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA G
Sbjct: 352  TDMHADYTGQGFDQLQDVISKIKENPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 411

Query: 1263 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1442
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+HTIGDAH+Y  HVRPLQ
Sbjct: 412  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHTIGDAHIYLNHVRPLQ 471

Query: 1443 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            +QLQKLPKPFP+LKINSEKR+IDSF AADF
Sbjct: 472  DQLQKLPKPFPVLKINSEKRNIDSFEAADF 501


>ref|XP_021628142.1| bifunctional dihydrofolate reductase-thymidylate synthase-like
            isoform X1 [Manihot esculenta]
 gb|OAY37221.1| hypothetical protein MANES_11G084400 [Manihot esculenta]
          Length = 527

 Score =  891 bits (2302), Expect = 0.0
 Identities = 428/510 (83%), Positives = 468/510 (91%), Gaps = 2/510 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MAG+   ++ NG+       QRTYQVVVAAT++MGIGKDGK+PWRLPSDLKFFKDVTMTT
Sbjct: 1    MAGEFKANLSNGNANVQPAAQRTYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKDVTMTT 60

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            SD  KKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVV+CGS+ SALEL
Sbjct: 61   SDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGSLNSALEL 120

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LAASPYC+SIEK FVIGGGQI REALNAPGCDAIH+T+IE  I+CDTFIP +D SVFQPW
Sbjct: 121  LAASPYCLSIEKAFVIGGGQILREALNAPGCDAIHMTEIETNIDCDTFIPTVDSSVFQPW 180

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 722
            YSSFP+VEN+IRYCF TYVRVRSS VE   + NGLSSD+ S++ KFE++KFSFLPK +FE
Sbjct: 181  YSSFPMVENSIRYCFATYVRVRSSVVESNGENNGLSSDSGSENSKFEVKKFSFLPKMVFE 240

Query: 723  KHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 902
            +HEE++YLR+V++IIS+GV KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGVVE
Sbjct: 241  RHEEFLYLRLVQDIISDGVLKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVVE 300

Query: 903  ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1082
            ELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGARY
Sbjct: 301  ELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQWRHFGARY 360

Query: 1083 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1262
            TDMHADYTGQGFDQLLDV+ KIK+NPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA G
Sbjct: 361  TDMHADYTGQGFDQLLDVIDKIKSNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 420

Query: 1263 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1442
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVC+LVPGDFIH  GDAHVY +HVRPLQ
Sbjct: 421  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLVPGDFIHVFGDAHVYSSHVRPLQ 480

Query: 1443 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            EQLQKLPKPFPIL IN EK++IDSFVAADF
Sbjct: 481  EQLQKLPKPFPILMINPEKKNIDSFVAADF 510


>gb|OMO75612.1| Thymidylate synthase [Corchorus olitorius]
          Length = 529

 Score =  890 bits (2300), Expect = 0.0
 Identities = 428/512 (83%), Positives = 470/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTM 182
            M+ D +M+I NG+G  +   DPQRT+Q+VVAAT+++GIGKDGK+PW+LPSDLKFFKDVT+
Sbjct: 1    MSADIMMNISNGNGNGNAQPDPQRTFQIVVAATKDLGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 183  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISAL 362
            TTSD  KKNAVIMGRKTWESIPL+HRPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQHRPLPGRLNVVLTRSGSFDIATAENVVICGSMASAL 120

Query: 363  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 542
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE RIECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETRIECDTFMPAIDSSVFQ 180

Query: 543  PWYSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 716
            PWYSSFP+VENNIRYCFTTYVRVR+SAVE   Q N    D+   + KFEIQKFSFLPK I
Sbjct: 181  PWYSSFPVVENNIRYCFTTYVRVRNSAVENLSQNNDKILDSIPATSKFEIQKFSFLPKMI 240

Query: 717  FEKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 896
            FEKHEEY+YL+MV++II++G  KDDRT TGT+S FGCQMRFNLR++FPLLTTKKVFWRGV
Sbjct: 241  FEKHEEYLYLKMVQDIIADGNLKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGV 300

Query: 897  VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1076
            VEELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1077 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1256
            RYTDMHADYTGQGFDQLLDV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1257 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1436
             GELSCQ YQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+H +GD HVY  HVRP
Sbjct: 421  NGELSCQTYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHVLGDTHVYSNHVRP 480

Query: 1437 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            LQEQLQKLPKPFPILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFPILKINPEKKNIDSFVASDF 512


>gb|OMO74316.1| Thymidylate synthase [Corchorus capsularis]
          Length = 529

 Score =  890 bits (2299), Expect = 0.0
 Identities = 427/512 (83%), Positives = 470/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTM 182
            M+ D +M+IPNG+G  +   DPQRT+Q+VVAAT+++GIGKDGK+PW+LPSDLKFFKDVT+
Sbjct: 1    MSADIMMNIPNGNGNGNAQPDPQRTFQIVVAATKDLGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 183  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISAL 362
            TTSD  KKNAVIMGRKTWESIPL+HRPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQHRPLPGRLNVVLTRSGSFDIATAENVVICGSMASAL 120

Query: 363  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 542
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE  IECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETNIECDTFMPAIDSSVFQ 180

Query: 543  PWYSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 716
            PWYSSFP+VENNIRYCFTTYVRVR+SAVE   Q      D+   + KFEIQKFSFLPK I
Sbjct: 181  PWYSSFPVVENNIRYCFTTYVRVRNSAVENLSQNKDKILDSIPATSKFEIQKFSFLPKMI 240

Query: 717  FEKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 896
            FEKHEEY+YL+MV++II++G  KDDRT TGT+S FGCQMRFNLR++FPLLTTKKVFWRGV
Sbjct: 241  FEKHEEYLYLKMVQDIIADGNLKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGV 300

Query: 897  VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1076
            VEELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1077 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1256
            RYTDMHADYTG+GFDQLLDV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGKGFDQLLDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1257 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1436
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+H +GD HVY  HVRP
Sbjct: 421  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHVLGDTHVYSNHVRP 480

Query: 1437 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            LQEQLQKLPKPFPILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFPILKINPEKKNIDSFVASDF 512


>ref|XP_021285499.1| bifunctional dihydrofolate reductase-thymidylate synthase-like
            isoform X1 [Herrania umbratica]
          Length = 529

 Score =  889 bits (2298), Expect = 0.0
 Identities = 428/512 (83%), Positives = 471/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTM 182
            M+ D +MSIPNG+G  +   DPQRTYQVVVAAT+++GIGKDGK+PW+LPSDLKFFKDVT+
Sbjct: 1    MSADIMMSIPNGNGNGNAQPDPQRTYQVVVAATKDLGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 183  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISAL 362
            TTSD  KKNAVIMGRKTWESIPL++RPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQNRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSAL 120

Query: 363  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 542
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE  IECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETSIECDTFMPSIDSSVFQ 180

Query: 543  PWYSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 716
            PW+SSFP+VENNIRYCFTT+VRVR+SAVE   Q +    D   D+GKFE++KFSFLPK I
Sbjct: 181  PWHSSFPVVENNIRYCFTTFVRVRNSAVEHISQNSDQVFDDKPDAGKFEVKKFSFLPKMI 240

Query: 717  FEKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 896
            FEKHEEY+YL+MV++IIS+G  KDDRT TGT S FGCQMRFNLRK+FPLLTTKKVFWRGV
Sbjct: 241  FEKHEEYLYLKMVQDIISDGNLKDDRTGTGTFSKFGCQMRFNLRKTFPLLTTKKVFWRGV 300

Query: 897  VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1076
            VEELLWFISGSTNAKVLQ+ GIHIW+GN SRD+LDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQDMGIHIWDGNASRDFLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1077 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1256
            RYTDMHADYTGQGFDQLLDV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1257 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1436
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDL+PGDFIH +GDAHVY  HVRP
Sbjct: 421  YGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVLGDAHVYSNHVRP 480

Query: 1437 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            LQEQLQKLPKPFPILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFPILKINPEKKNIDSFVASDF 512


>ref|XP_007042127.2| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Theobroma cacao]
          Length = 529

 Score =  889 bits (2298), Expect = 0.0
 Identities = 429/512 (83%), Positives = 471/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTM 182
            M+ D +MSIPNG+G  +   DPQRTYQVVVAAT++MGIGKDGK+PW+LPSDLKFFKDVT+
Sbjct: 1    MSADIMMSIPNGNGNGNAQPDPQRTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 183  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISAL 362
            TTSD  KKNAVIMGRKTWESIPL++RPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQNRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSAL 120

Query: 363  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 542
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE  IECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETSIECDTFMPSIDSSVFQ 180

Query: 543  PWYSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 716
            PWYSSFP+VEN+IRYCFTT+VRVR+SAVE   Q +    D   D+GKFE++KFSFLPK I
Sbjct: 181  PWYSSFPVVENDIRYCFTTFVRVRNSAVEHISQNSDQVFDDKPDAGKFEVKKFSFLPKMI 240

Query: 717  FEKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 896
            FEKHEEY+YL+MV++IIS+G  KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGV
Sbjct: 241  FEKHEEYLYLKMVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGV 300

Query: 897  VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1076
            VEELLWFISGSTNAKVLQ+KGIHIW+GN SRD+LDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQDKGIHIWDGNASRDFLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1077 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1256
            RYTDMHADYTGQGFDQL DV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGQGFDQLSDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1257 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1436
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIH +GDAHVY  HVRP
Sbjct: 421  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHVLGDAHVYTNHVRP 480

Query: 1437 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            LQEQLQKLPKPF ILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFSILKINPEKKNIDSFVASDF 512


>gb|EOX97956.1| Thymidylate synthase 1 isoform 1 [Theobroma cacao]
 gb|EOX97958.1| Thymidylate synthase 1 isoform 1 [Theobroma cacao]
          Length = 529

 Score =  888 bits (2294), Expect = 0.0
 Identities = 428/512 (83%), Positives = 471/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTM 182
            M+ D +MSIPNG+G  +   DPQRTYQVVVAAT++MGIGKDGK+PW+LPSDLKFFKDVT+
Sbjct: 1    MSADIMMSIPNGNGNGNAQPDPQRTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 183  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISAL 362
            TTSD  KKNAVIMGRKTWESIPL++RPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQNRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSAL 120

Query: 363  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 542
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE  IECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETSIECDTFMPSIDSSVFQ 180

Query: 543  PWYSSFPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 716
            PWYSSFP+VEN+IRYCFTT+VRVR+SAVE   Q +    D   D+GKFE++KFSFLPK I
Sbjct: 181  PWYSSFPVVENDIRYCFTTFVRVRNSAVEHISQNSDQVFDDKPDAGKFEVKKFSFLPKMI 240

Query: 717  FEKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 896
            F+KHEEY+YL+MV++IIS+G  KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGV
Sbjct: 241  FKKHEEYLYLKMVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGV 300

Query: 897  VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1076
            VEELLWFISGSTNAKVLQ+KGIHIW+GN SRD+LDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQDKGIHIWDGNASRDFLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1077 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1256
            RYTDMHADYTGQGFDQL DV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGQGFDQLSDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1257 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1436
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIH +GDAHVY  HVRP
Sbjct: 421  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHVLGDAHVYTNHVRP 480

Query: 1437 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            LQEQLQKLPKPF ILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFSILKINPEKKNIDSFVASDF 512


>ref|XP_011037491.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like [Populus euphratica]
 ref|XP_011037492.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like [Populus euphratica]
          Length = 528

 Score =  887 bits (2293), Expect = 0.0
 Identities = 425/511 (83%), Positives = 471/511 (92%), Gaps = 3/511 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTD-PQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMT 185
            M+GD++ ++ NG+  T    PQ+TYQVVVAAT++MGIGKDGK+PW+LPSDLKFFKD+T+T
Sbjct: 1    MSGDSVANLSNGNANTQQPAPQKTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDLTLT 60

Query: 186  TSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALE 365
            T D  KKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVVICGSM SALE
Sbjct: 61   TMDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALE 120

Query: 366  LLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQP 545
            LLAASPYC+SIEKVFVIGGGQI RE+LNAPGCDAIHIT+IE   +CDTFIP +D SVFQP
Sbjct: 121  LLAASPYCLSIEKVFVIGGGQILRESLNAPGCDAIHITEIEMDFDCDTFIPAIDTSVFQP 180

Query: 546  WYSSFPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIF 719
            WYSSFP VEN+IR+CFTTYVRVRSS +E   Q NG +SD NS++ KFE+ KFSFLPK +F
Sbjct: 181  WYSSFPNVENDIRHCFTTYVRVRSSTIESHSQNNGENSDGNSENSKFEVMKFSFLPKMVF 240

Query: 720  EKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVV 899
            E+HEEY+YLRMV++IIS+G  KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGVV
Sbjct: 241  ERHEEYLYLRMVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKNFPLLTTKKVFWRGVV 300

Query: 900  EELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGAR 1079
            EELLWFISGST+AKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGAR
Sbjct: 301  EELLWFISGSTSAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQWRHFGAR 360

Query: 1080 YTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAK 1259
            YTDMHADYTGQGFDQLLDV+ KIKNNP+DRRII+SAWNPSDLKLMALPPCHMFAQFYVA 
Sbjct: 361  YTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIIISAWNPSDLKLMALPPCHMFAQFYVAN 420

Query: 1260 GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPL 1439
            GELSCQMYQRSADMGLGVPFNIASYALLTC+IAHVCDL+PGDF+H IGDAHVY TH+RPL
Sbjct: 421  GELSCQMYQRSADMGLGVPFNIASYALLTCIIAHVCDLIPGDFVHVIGDAHVYHTHIRPL 480

Query: 1440 QEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            QEQL+KLPKPFPILKINSEK+DID+FVAADF
Sbjct: 481  QEQLRKLPKPFPILKINSEKKDIDTFVAADF 511


>ref|XP_010254750.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X2 [Nelumbo nucifera]
          Length = 569

 Score =  887 bits (2291), Expect = 0.0
 Identities = 429/511 (83%), Positives = 462/511 (90%), Gaps = 2/511 (0%)
 Frame = +3

Query: 6    LMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMT 185
            +MAG+T+M++PNG+     DP+RT+QVVVAAT++MGIGKDGK+PWRLPSDLKFF++VTM 
Sbjct: 42   VMAGETIMNVPNGNASIQPDPKRTFQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTMG 101

Query: 186  TSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALE 365
            TSDP KKNAVIMGRKTWE IP EHRPLP RLNVVLTRSGSFDIATAENVVICGSM SALE
Sbjct: 102  TSDPAKKNAVIMGRKTWEGIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALE 161

Query: 366  LLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQP 545
            LLA+SPYC+SIEKVFVIGGGQI RE+LNAP CDAIHIT+IE   ECDTFIPP++ SVFQP
Sbjct: 162  LLASSPYCLSIEKVFVIGGGQILRESLNAPECDAIHITEIETSFECDTFIPPIELSVFQP 221

Query: 546  WYSSFPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIF 719
            WYSSFPL+ENNIR  F TYVRVR SA E   Q NG   D NS++ KFEI+KFSFLPK IF
Sbjct: 222  WYSSFPLIENNIRCSFVTYVRVRRSAAEYLYQDNGGMFDGNSNNTKFEIEKFSFLPKMIF 281

Query: 720  EKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVV 899
            E+HEEYMYLR+VE+IISNG  KDDRT TGT+S FGCQM FNLRKSFPLLTTKKVFWRGVV
Sbjct: 282  ERHEEYMYLRLVEDIISNGNQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFWRGVV 341

Query: 900  EELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGAR 1079
            EELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGPIYGFQWRH GAR
Sbjct: 342  EELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRHHGAR 401

Query: 1080 YTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAK 1259
            YT+MHADY+GQGFDQLLDV+ KIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYV  
Sbjct: 402  YTNMHADYSGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVVN 461

Query: 1260 GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPL 1439
            GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDL+PGDFIH IGDAHVY THVRPL
Sbjct: 462  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTHVRPL 521

Query: 1440 QEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            QEQLQKLPKPFPILKIN  K+DIDSFVA DF
Sbjct: 522  QEQLQKLPKPFPILKINPHKKDIDSFVATDF 552


>ref|XP_010254749.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Nelumbo nucifera]
          Length = 578

 Score =  887 bits (2291), Expect = 0.0
 Identities = 429/511 (83%), Positives = 462/511 (90%), Gaps = 2/511 (0%)
 Frame = +3

Query: 6    LMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMT 185
            +MAG+T+M++PNG+     DP+RT+QVVVAAT++MGIGKDGK+PWRLPSDLKFF++VTM 
Sbjct: 51   VMAGETIMNVPNGNASIQPDPKRTFQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTMG 110

Query: 186  TSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALE 365
            TSDP KKNAVIMGRKTWE IP EHRPLP RLNVVLTRSGSFDIATAENVVICGSM SALE
Sbjct: 111  TSDPAKKNAVIMGRKTWEGIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALE 170

Query: 366  LLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQP 545
            LLA+SPYC+SIEKVFVIGGGQI RE+LNAP CDAIHIT+IE   ECDTFIPP++ SVFQP
Sbjct: 171  LLASSPYCLSIEKVFVIGGGQILRESLNAPECDAIHITEIETSFECDTFIPPIELSVFQP 230

Query: 546  WYSSFPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIF 719
            WYSSFPL+ENNIR  F TYVRVR SA E   Q NG   D NS++ KFEI+KFSFLPK IF
Sbjct: 231  WYSSFPLIENNIRCSFVTYVRVRRSAAEYLYQDNGGMFDGNSNNTKFEIEKFSFLPKMIF 290

Query: 720  EKHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVV 899
            E+HEEYMYLR+VE+IISNG  KDDRT TGT+S FGCQM FNLRKSFPLLTTKKVFWRGVV
Sbjct: 291  ERHEEYMYLRLVEDIISNGNQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFWRGVV 350

Query: 900  EELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGAR 1079
            EELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGPIYGFQWRH GAR
Sbjct: 351  EELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRHHGAR 410

Query: 1080 YTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAK 1259
            YT+MHADY+GQGFDQLLDV+ KIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYV  
Sbjct: 411  YTNMHADYSGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVVN 470

Query: 1260 GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPL 1439
            GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDL+PGDFIH IGDAHVY THVRPL
Sbjct: 471  GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTHVRPL 530

Query: 1440 QEQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            QEQLQKLPKPFPILKIN  K+DIDSFVA DF
Sbjct: 531  QEQLQKLPKPFPILKINPHKKDIDSFVATDF 561


>ref|XP_010254751.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X3 [Nelumbo nucifera]
 ref|XP_010254752.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X3 [Nelumbo nucifera]
          Length = 527

 Score =  886 bits (2290), Expect = 0.0
 Identities = 429/510 (84%), Positives = 461/510 (90%), Gaps = 2/510 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MAG+T+M++PNG+     DP+RT+QVVVAAT++MGIGKDGK+PWRLPSDLKFF++VTM T
Sbjct: 1    MAGETIMNVPNGNASIQPDPKRTFQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTMGT 60

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            SDP KKNAVIMGRKTWE IP EHRPLP RLNVVLTRSGSFDIATAENVVICGSM SALEL
Sbjct: 61   SDPAKKNAVIMGRKTWEGIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALEL 120

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LA+SPYC+SIEKVFVIGGGQI RE+LNAP CDAIHIT+IE   ECDTFIPP++ SVFQPW
Sbjct: 121  LASSPYCLSIEKVFVIGGGQILRESLNAPECDAIHITEIETSFECDTFIPPIELSVFQPW 180

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 722
            YSSFPL+ENNIR  F TYVRVR SA E   Q NG   D NS++ KFEI+KFSFLPK IFE
Sbjct: 181  YSSFPLIENNIRCSFVTYVRVRRSAAEYLYQDNGGMFDGNSNNTKFEIEKFSFLPKMIFE 240

Query: 723  KHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 902
            +HEEYMYLR+VE+IISNG  KDDRT TGT+S FGCQM FNLRKSFPLLTTKKVFWRGVVE
Sbjct: 241  RHEEYMYLRLVEDIISNGNQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFWRGVVE 300

Query: 903  ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1082
            ELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGPIYGFQWRH GARY
Sbjct: 301  ELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRHHGARY 360

Query: 1083 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1262
            T+MHADY+GQGFDQLLDV+ KIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYV  G
Sbjct: 361  TNMHADYSGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVVNG 420

Query: 1263 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1442
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDL+PGDFIH IGDAHVY THVRPLQ
Sbjct: 421  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTHVRPLQ 480

Query: 1443 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            EQLQKLPKPFPILKIN  K+DIDSFVA DF
Sbjct: 481  EQLQKLPKPFPILKINPHKKDIDSFVATDF 510


>ref|XP_020533467.1| bifunctional dihydrofolate reductase-thymidylate synthase 1 [Jatropha
            curcas]
 gb|KDP41765.1| hypothetical protein JCGZ_26783 [Jatropha curcas]
          Length = 525

 Score =  885 bits (2288), Expect = 0.0
 Identities = 424/510 (83%), Positives = 468/510 (91%), Gaps = 2/510 (0%)
 Frame = +3

Query: 9    MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDVTMTT 188
            MAGD+  S+ NG+    +DP+RTYQVVVAAT++MGIGK+GK+PWRLPSDLKFFKDVT+TT
Sbjct: 1    MAGDSKASLSNGTANIQSDPRRTYQVVVAATRDMGIGKEGKLPWRLPSDLKFFKDVTLTT 60

Query: 189  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMISALEL 368
            SD  +KNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVVICGS+ SALEL
Sbjct: 61   SDSGRKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSLTSALEL 120

Query: 369  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 548
            LAASPYC+SIEKVF+IGGGQI RE+LNAPGCDAIHIT+IE  I+CDTFIP +D SVFQPW
Sbjct: 121  LAASPYCLSIEKVFIIGGGQILRESLNAPGCDAIHITEIETSIDCDTFIPKIDSSVFQPW 180

Query: 549  YSSFPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 722
            YSSFP+VENN+RYCF TYVRVR SAVE   Q NGLSSD +    KFE++KFSFLPK +FE
Sbjct: 181  YSSFPIVENNVRYCFATYVRVRVSAVESHGQDNGLSSDNSYI--KFEVKKFSFLPKMVFE 238

Query: 723  KHEEYMYLRMVENIISNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 902
            +HEE++YLR+V++IIS+G  KDDRT TGT+S FGCQMRFNLR++FPLLTTKKVFWRGVVE
Sbjct: 239  RHEEFLYLRLVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGVVE 298

Query: 903  ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1082
            ELLWFISGSTN KVLQEKGIHIW+GN SRDYLD IGL DREEGDLGP+YGFQWRHFGARY
Sbjct: 299  ELLWFISGSTNCKVLQEKGIHIWDGNASRDYLDGIGLKDREEGDLGPVYGFQWRHFGARY 358

Query: 1083 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1262
            TDMHADYTGQGFDQLLDV+ KIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA G
Sbjct: 359  TDMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 418

Query: 1263 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1442
            ELSCQMYQRSADMGLGVPFNIASYALLTC+++HVCDLVPGDF+H +GDAHVY THVRPLQ
Sbjct: 419  ELSCQMYQRSADMGLGVPFNIASYALLTCIVSHVCDLVPGDFVHVLGDAHVYRTHVRPLQ 478

Query: 1443 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1532
            EQLQK PKPFPILKIN EK++IDSFVAADF
Sbjct: 479  EQLQKPPKPFPILKINPEKKNIDSFVAADF 508