BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Acanthopanax21_contig00026287
         (1271 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_017218991.1| PREDICTED: dihydrofolate synthetase isoform ...   613   0.0  
ref|XP_017218990.1| PREDICTED: dihydrofolate synthetase isoform ...   614   0.0  
gb|KZM87282.1| hypothetical protein DCAR_024416 [Daucus carota s...   590   0.0  
ref|XP_002267695.2| PREDICTED: dihydrofolate synthetase isoform ...   587   0.0  
ref|XP_010662583.1| PREDICTED: dihydrofolate synthetase isoform ...   577   0.0  
ref|XP_023904165.1| dihydrofolate synthetase-like [Quercus suber...   576   0.0  
ref|XP_006490572.1| PREDICTED: dihydrofolate synthetase isoform ...   573   0.0  
gb|ESR35358.1| hypothetical protein CICLE_v10007115mg [Citrus cl...   573   0.0  
ref|XP_012090121.1| dihydrofolate synthetase [Jatropha curcas]        572   0.0  
ref|XP_022006741.1| dihydrofolate synthetase [Helianthus annuus]...   572   0.0  
gb|KVI10194.1| Folylpolyglutamate synthetase [Cynara cardunculus...   571   0.0  
dbj|GAV66233.1| Mur_ligase_M domain-containing protein [Cephalot...   570   0.0  
ref|XP_024046876.1| dihydrofolate synthetase isoform X2 [Citrus ...   563   0.0  
ref|XP_007038953.2| PREDICTED: dihydrofolate synthetase isoform ...   566   0.0  
ref|XP_023740748.1| dihydrofolate synthetase isoform X1 [Lactuca...   566   0.0  
ref|XP_008234781.1| PREDICTED: dihydrofolate synthetase [Prunus ...   566   0.0  
gb|KDP22174.1| hypothetical protein JCGZ_26005 [Jatropha curcas]      565   0.0  
ref|XP_021616708.1| dihydrofolate synthetase [Manihot esculenta]...   566   0.0  
ref|XP_015389579.1| PREDICTED: dihydrofolate synthetase isoform ...   566   0.0  
ref|XP_010249972.1| PREDICTED: dihydrofolate synthetase isoform ...   565   0.0  

>ref|XP_017218991.1| PREDICTED: dihydrofolate synthetase isoform X2 [Daucus carota subsp.
            sativus]
          Length = 457

 Score =  613 bits (1580), Expect = 0.0
 Identities = 313/422 (74%), Positives = 360/422 (85%), Gaps = 1/422 (0%)
 Frame = -1

Query: 1265 PFNRGFSVL-QEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGN 1089
            P NRG S L Q+D +LK+   YLDN KNYEK GVP GAGTDS+DGFD           GN
Sbjct: 26   PLNRGLSQLPQQDPELKDLLSYLDNRKNYEKLGVPTGAGTDSDDGFDLGRMTSLMQFLGN 85

Query: 1088 PQSKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSA 909
            P SKF+A+HVAGTKGKGSTAAFLSNILRA+GYSVGCYTSPHI +IRE ISVG++SEPVSA
Sbjct: 86   PHSKFQAIHVAGTKGKGSTAAFLSNILRAQGYSVGCYTSPHIHSIRERISVGKISEPVSA 145

Query: 908  KSLNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDAT 729
            +SLN LFQR K +LDQA+E E+  ISHFEVLTA+AF+LFADENID+AV+EAGLGGARDAT
Sbjct: 146  RSLNLLFQRSKMMLDQAIEKEDKRISHFEVLTAMAFKLFADENIDIAVVEAGLGGARDAT 205

Query: 728  NIISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILR 549
            NI+SSS LAASVITTIGEEH+AALGGSLESIA+AK+GI+K+ RPLVLGGP+L ++E ILR
Sbjct: 206  NILSSSTLAASVITTIGEEHMAALGGSLESIAIAKSGIVKTNRPLVLGGPYLPEIESILR 265

Query: 548  GKASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCML 369
             KAS MGSPVVSASD GN+S+IKG+ ++CGKPCQ+CDIVLEI+ D+KL  +LLNVNL ML
Sbjct: 266  AKASSMGSPVVSASDSGNKSVIKGVGDVCGKPCQTCDIVLEIESDLKLCTQLLNVNLRML 325

Query: 368  GPHQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGAT 189
            GPHQLQN          LRHQGW I+D AIR GLEHT LLGRS FL+S+EAEA+GLPG  
Sbjct: 326  GPHQLQNAATATCAALCLRHQGWSIADEAIRTGLEHTELLGRSHFLSSEEAEAIGLPGTK 385

Query: 188  ILLDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            ILLDGAHTKESAKALADTI+MTFPKARL+LVVAMASDKDHI+FA+ELL VRQL+AV+L +
Sbjct: 386  ILLDGAHTKESAKALADTIRMTFPKARLVLVVAMASDKDHISFAKELLQVRQLEAVVLAD 445

Query: 8    VS 3
            VS
Sbjct: 446  VS 447


>ref|XP_017218990.1| PREDICTED: dihydrofolate synthetase isoform X1 [Daucus carota subsp.
            sativus]
          Length = 540

 Score =  614 bits (1584), Expect = 0.0
 Identities = 314/422 (74%), Positives = 361/422 (85%), Gaps = 1/422 (0%)
 Frame = -1

Query: 1265 PFNRGFSVL-QEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGN 1089
            P NRG S L Q+D +LK+   YLDN KNYEK GVP GAGTDS+DGFD           GN
Sbjct: 26   PLNRGLSQLPQQDPELKDLLSYLDNRKNYEKLGVPTGAGTDSDDGFDLGRMTSLMQFLGN 85

Query: 1088 PQSKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSA 909
            P SKF+A+HVAGTKGKGSTAAFLSNILRA+GYSVGCYTSPHI +IRE ISVG++SEPVSA
Sbjct: 86   PHSKFQAIHVAGTKGKGSTAAFLSNILRAQGYSVGCYTSPHIHSIRERISVGKISEPVSA 145

Query: 908  KSLNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDAT 729
            +SLN LFQR K +LDQA+E E+  ISHFEVLTA+AF+LFADENID+AV+EAGLGGARDAT
Sbjct: 146  RSLNLLFQRSKMMLDQAIEKEDKRISHFEVLTAMAFKLFADENIDIAVVEAGLGGARDAT 205

Query: 728  NIISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILR 549
            NI+SSS LAASVITTIGEEH+AALGGSLESIA+AK+GI+K+ RPLVLGGP+L ++E ILR
Sbjct: 206  NILSSSTLAASVITTIGEEHMAALGGSLESIAIAKSGIVKTNRPLVLGGPYLPEIESILR 265

Query: 548  GKASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCML 369
             KAS MGSPVVSASD GN+S+IKG+ ++CGKPCQ+CDIVLEI+ D+KL  +LLNVNL ML
Sbjct: 266  AKASSMGSPVVSASDSGNKSVIKGVGDVCGKPCQTCDIVLEIESDLKLCTQLLNVNLRML 325

Query: 368  GPHQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGAT 189
            GPHQLQN          LRHQGW I+D AIR GLEHT LLGRS FL+S+EAEA+GLPG  
Sbjct: 326  GPHQLQNAATATCAALCLRHQGWSIADEAIRTGLEHTELLGRSHFLSSEEAEAIGLPGTK 385

Query: 188  ILLDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            ILLDGAHTKESAKALADTI+MTFPKARL+LVVAMASDKDHI+FA+ELL VRQL+AV+LT+
Sbjct: 386  ILLDGAHTKESAKALADTIRMTFPKARLVLVVAMASDKDHISFAKELLQVRQLEAVVLTK 445

Query: 8    VS 3
            VS
Sbjct: 446  VS 447


>gb|KZM87282.1| hypothetical protein DCAR_024416 [Daucus carota subsp. sativus]
          Length = 534

 Score =  590 bits (1521), Expect = 0.0
 Identities = 307/422 (72%), Positives = 353/422 (83%), Gaps = 1/422 (0%)
 Frame = -1

Query: 1265 PFNRGFSVL-QEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGN 1089
            P NRG S L Q+D +LK+   YLDN KNYEK GVP GAGTDS+DGFD           GN
Sbjct: 26   PLNRGLSQLPQQDPELKDLLSYLDNRKNYEKLGVPTGAGTDSDDGFDLGRMTSLMQFLGN 85

Query: 1088 PQSKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSA 909
            P SKF+A+HVAGTKGKGSTAAFLSNILRA+GYS+ C  SPHI +IRE ISVG++SEPVSA
Sbjct: 86   PHSKFQAIHVAGTKGKGSTAAFLSNILRAQGYSLCCLNSPHIHSIRERISVGKISEPVSA 145

Query: 908  KSLNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDAT 729
            +SLN LFQR K +LDQA+E E+  ISHFEVLTA+AF+LFADENID+AV+EAGLGGARDAT
Sbjct: 146  RSLNLLFQRSKMMLDQAIEKEDKRISHFEVLTAMAFKLFADENIDIAVVEAGLGGARDAT 205

Query: 728  NIISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILR 549
            NI+SSS LAASVITTIGEEH+AALGGSLESIA+AK+GI      LVLGGP+L ++E ILR
Sbjct: 206  NILSSSTLAASVITTIGEEHMAALGGSLESIAIAKSGI------LVLGGPYLPEIESILR 259

Query: 548  GKASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCML 369
             KAS MGSPVVSASD GN+S+IKG+ ++CGKPCQ+CDIVLEI+ D+KL  +LLNVNL ML
Sbjct: 260  AKASSMGSPVVSASDSGNKSVIKGVGDVCGKPCQTCDIVLEIESDLKLCTQLLNVNLRML 319

Query: 368  GPHQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGAT 189
            GPHQLQN          LRHQGW I+D AIR GLEHT LLGRS FL+S+EAEA+GLPG  
Sbjct: 320  GPHQLQNAATATCAALCLRHQGWSIADEAIRTGLEHTELLGRSHFLSSEEAEAIGLPGTK 379

Query: 188  ILLDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            ILLDGAHTKESAKALADTI+MTFPKARL+LVVAMASDKDHI+FA+ELL VRQL+AV+LT+
Sbjct: 380  ILLDGAHTKESAKALADTIRMTFPKARLVLVVAMASDKDHISFAKELLQVRQLEAVVLTK 439

Query: 8    VS 3
            VS
Sbjct: 440  VS 441


>ref|XP_002267695.2| PREDICTED: dihydrofolate synthetase isoform X2 [Vitis vinifera]
 emb|CBI22549.3| unnamed protein product, partial [Vitis vinifera]
          Length = 536

 Score =  587 bits (1512), Expect = 0.0
 Identities = 306/420 (72%), Positives = 345/420 (82%)
 Frame = -1

Query: 1262 FNRGFSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQ 1083
            F R FS    + +LK+F +YLDNLKNYEK GVP  AGTDS  GFD           GNP+
Sbjct: 16   FKRSFST---EPELKDFLNYLDNLKNYEKCGVPKDAGTDSSHGFDLGRMNRLMDRLGNPE 72

Query: 1082 SKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKS 903
            + FKAVH+AGTKGKGSTAAFL+NILR EGY+VGCYTSPH++TIRE IS+G+L EPVSAK+
Sbjct: 73   TGFKAVHIAGTKGKGSTAAFLANILRTEGYAVGCYTSPHVRTIRERISLGKLGEPVSAKA 132

Query: 902  LNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNI 723
            LNCLF RIK ILD+AV LENG +SHFE+LTA+AF+LFA EN+DVAVIEAGLGGARDATNI
Sbjct: 133  LNCLFHRIKPILDEAVALENGRLSHFEILTAMAFKLFAQENVDVAVIEAGLGGARDATNI 192

Query: 722  ISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGK 543
            ISSSGLAA+VITTIGEEHLAALGGSLESIAMAK+GIIK G PLVLGGPFL  +EHI   K
Sbjct: 193  ISSSGLAAAVITTIGEEHLAALGGSLESIAMAKSGIIKQGCPLVLGGPFLPHIEHIFLDK 252

Query: 542  ASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGP 363
            AS M SPVVSAS PGNRS +KG++   GKP QSCDIV+E++RD KLFIEL +V L MLG 
Sbjct: 253  ASSMCSPVVSASGPGNRSAVKGVSKSNGKPFQSCDIVIEVERDFKLFIELFDVKLQMLGI 312

Query: 362  HQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATIL 183
            HQLQN          LR +GW+ISD +I AGLEH YLLGRSQFLTS EAE LGLPGATI+
Sbjct: 313  HQLQNAATATCVALCLRDKGWRISDESIHAGLEHAYLLGRSQFLTSTEAETLGLPGATIM 372

Query: 182  LDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTEVS 3
            LDGAHTKESAKAL DTIQMTFP+ARL L+VAMASDKDH+AFARE LS  QL+AV LTEV+
Sbjct: 373  LDGAHTKESAKALVDTIQMTFPEARLALIVAMASDKDHMAFAREFLSGGQLEAVFLTEVN 432


>ref|XP_010662583.1| PREDICTED: dihydrofolate synthetase isoform X1 [Vitis vinifera]
 ref|XP_019081777.1| PREDICTED: dihydrofolate synthetase isoform X1 [Vitis vinifera]
          Length = 549

 Score =  577 bits (1488), Expect = 0.0
 Identities = 306/433 (70%), Positives = 345/433 (79%), Gaps = 13/433 (3%)
 Frame = -1

Query: 1262 FNRGFSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQ 1083
            F R FS    + +LK+F +YLDNLKNYEK GVP  AGTDS  GFD           GNP+
Sbjct: 16   FKRSFST---EPELKDFLNYLDNLKNYEKCGVPKDAGTDSSHGFDLGRMNRLMDRLGNPE 72

Query: 1082 SKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKS 903
            + FKAVH+AGTKGKGSTAAFL+NILR EGY+VGCYTSPH++TIRE IS+G+L EPVSAK+
Sbjct: 73   TGFKAVHIAGTKGKGSTAAFLANILRTEGYAVGCYTSPHVRTIRERISLGKLGEPVSAKA 132

Query: 902  LNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNI 723
            LNCLF RIK ILD+AV LENG +SHFE+LTA+AF+LFA EN+DVAVIEAGLGGARDATNI
Sbjct: 133  LNCLFHRIKPILDEAVALENGRLSHFEILTAMAFKLFAQENVDVAVIEAGLGGARDATNI 192

Query: 722  ISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRP-------------LVLGG 582
            ISSSGLAA+VITTIGEEHLAALGGSLESIAMAK+GIIK G P             LVLGG
Sbjct: 193  ISSSGLAAAVITTIGEEHLAALGGSLESIAMAKSGIIKQGCPVRWFSLHIYSALWLVLGG 252

Query: 581  PFLSKVEHILRGKASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLF 402
            PFL  +EHI   KAS M SPVVSAS PGNRS +KG++   GKP QSCDIV+E++RD KLF
Sbjct: 253  PFLPHIEHIFLDKASSMCSPVVSASGPGNRSAVKGVSKSNGKPFQSCDIVIEVERDFKLF 312

Query: 401  IELLNVNLCMLGPHQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSK 222
            IEL +V L MLG HQLQN          LR +GW+ISD +I AGLEH YLLGRSQFLTS 
Sbjct: 313  IELFDVKLQMLGIHQLQNAATATCVALCLRDKGWRISDESIHAGLEHAYLLGRSQFLTST 372

Query: 221  EAEALGLPGATILLDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLS 42
            EAE LGLPGATI+LDGAHTKESAKAL DTIQMTFP+ARL L+VAMASDKDH+AFARE LS
Sbjct: 373  EAETLGLPGATIMLDGAHTKESAKALVDTIQMTFPEARLALIVAMASDKDHMAFAREFLS 432

Query: 41   VRQLDAVILTEVS 3
              QL+AV LTEV+
Sbjct: 433  GGQLEAVFLTEVN 445


>ref|XP_023904165.1| dihydrofolate synthetase-like [Quercus suber]
 gb|POE45606.1| dihydrofolate synthetase [Quercus suber]
          Length = 553

 Score =  576 bits (1485), Expect = 0.0
 Identities = 300/416 (72%), Positives = 343/416 (82%)
 Frame = -1

Query: 1256 RGFSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSK 1077
            R FS   E+ +LKE  +Y+D+LKNYEK GVP GAGTDS+DGFD           GNPQ++
Sbjct: 32   RWFSAHSEEPELKELMEYMDSLKNYEKVGVPKGAGTDSDDGFDLGRMRRLMERLGNPQAQ 91

Query: 1076 FKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLN 897
            FKAVH+AGTKGKGSTAAFLSNILR EGYSVGCY+SPHIQTIRE IS+GR  EPVSAK+LN
Sbjct: 92   FKAVHIAGTKGKGSTAAFLSNILRVEGYSVGCYSSPHIQTIRERISLGRFGEPVSAKTLN 151

Query: 896  CLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIIS 717
            CLF +IK ILDQA++ ENG+ISHFE+ TA+AF LFA EN+D+AVIEAGLGGARDATNIIS
Sbjct: 152  CLFLQIKKILDQAMKHENGHISHFEIFTAMAFTLFARENVDIAVIEAGLGGARDATNIIS 211

Query: 716  SSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKAS 537
            SSGLAASVITTIGEEHLAALGGSLESIAMAK+GIIK G PLVLGGPFL  +E ILR KA 
Sbjct: 212  SSGLAASVITTIGEEHLAALGGSLESIAMAKSGIIKHGCPLVLGGPFLPHIECILRDKAL 271

Query: 536  LMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQ 357
             M SPVVSASD GN+S IKGI+ + G+P QSCD+V++I+RD KLF+ELL+V LCMLG HQ
Sbjct: 272  SMSSPVVSASDAGNQSTIKGISRMNGRPYQSCDLVIQIERDFKLFLELLDVKLCMLGSHQ 331

Query: 356  LQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLD 177
            LQN          LR+ GW+ISD +IRAGLEHT+LLGRSQ LTSKE EALGL G T+LLD
Sbjct: 332  LQNAATATCAALCLRNLGWRISDGSIRAGLEHTFLLGRSQILTSKETEALGLHGTTVLLD 391

Query: 176  GAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            GAHTKESA AL  TI+MTF +A L LVVAMASDKDH+ FARE LS  +L+AV+LTE
Sbjct: 392  GAHTKESANALVKTIKMTFGEAPLFLVVAMASDKDHVGFAREFLSGGELEAVLLTE 447


>ref|XP_006490572.1| PREDICTED: dihydrofolate synthetase isoform X2 [Citrus sinensis]
 ref|XP_024046873.1| dihydrofolate synthetase isoform X1 [Citrus clementina]
          Length = 556

 Score =  573 bits (1477), Expect = 0.0
 Identities = 295/414 (71%), Positives = 344/414 (83%)
 Frame = -1

Query: 1250 FSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSKFK 1071
            FS   E+ +L  F +YLD+LKN+EKSGVP GAGTDS+DGFD           GNP SKFK
Sbjct: 36   FSTSSEEPELMNFMNYLDSLKNFEKSGVPKGAGTDSDDGFDLGRMNRLMDRLGNPHSKFK 95

Query: 1070 AVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLNCL 891
             VH+AGTKGKGSTAAFLS+ILRAEGYSVGCYTSPHI+TIRE ++VGRL+ PVSAK+LNCL
Sbjct: 96   TVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCL 155

Query: 890  FQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIISSS 711
            F +IK +LD+A+ LENG I+HFEVLTA+AF LFA  ++D+AVIEAGLGGARDATNIISSS
Sbjct: 156  FHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARDATNIISSS 215

Query: 710  GLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKASLM 531
            GLAASVITTIGEEH AALGGSLE+IAMAK+GIIK GRPLVLGGPFL  +EHILR +ASLM
Sbjct: 216  GLAASVITTIGEEHTAALGGSLETIAMAKSGIIKYGRPLVLGGPFLPHIEHILRDEASLM 275

Query: 530  GSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQLQ 351
             S VVSA D G R+ I G++    +PCQSCDI+++ +RD+KL IELL+V LCM+G HQL 
Sbjct: 276  CSQVVSAYDAGIRATINGLSMFNDRPCQSCDIIVQAERDLKLSIELLDVKLCMIGNHQLH 335

Query: 350  NXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLDGA 171
            N          LR QGWKISD ++RAGLE+T L+GR+QFLTSK+AE LGLPGATIL+DGA
Sbjct: 336  NALTATCAALCLRDQGWKISDGSVRAGLENTCLVGRTQFLTSKQAELLGLPGATILVDGA 395

Query: 170  HTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            HTKESAKAL DTIQMTFP+ARL LVVAMA DKDH+AFA+E LS R+LD+VILTE
Sbjct: 396  HTKESAKALVDTIQMTFPQARLALVVAMAIDKDHLAFAKEFLSGRKLDSVILTE 449


>gb|ESR35358.1| hypothetical protein CICLE_v10007115mg [Citrus clementina]
          Length = 565

 Score =  573 bits (1477), Expect = 0.0
 Identities = 295/414 (71%), Positives = 344/414 (83%)
 Frame = -1

Query: 1250 FSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSKFK 1071
            FS   E+ +L  F +YLD+LKN+EKSGVP GAGTDS+DGFD           GNP SKFK
Sbjct: 45   FSTSSEEPELMNFMNYLDSLKNFEKSGVPKGAGTDSDDGFDLGRMNRLMDRLGNPHSKFK 104

Query: 1070 AVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLNCL 891
             VH+AGTKGKGSTAAFLS+ILRAEGYSVGCYTSPHI+TIRE ++VGRL+ PVSAK+LNCL
Sbjct: 105  TVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCL 164

Query: 890  FQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIISSS 711
            F +IK +LD+A+ LENG I+HFEVLTA+AF LFA  ++D+AVIEAGLGGARDATNIISSS
Sbjct: 165  FHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARDATNIISSS 224

Query: 710  GLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKASLM 531
            GLAASVITTIGEEH AALGGSLE+IAMAK+GIIK GRPLVLGGPFL  +EHILR +ASLM
Sbjct: 225  GLAASVITTIGEEHTAALGGSLETIAMAKSGIIKYGRPLVLGGPFLPHIEHILRDEASLM 284

Query: 530  GSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQLQ 351
             S VVSA D G R+ I G++    +PCQSCDI+++ +RD+KL IELL+V LCM+G HQL 
Sbjct: 285  CSQVVSAYDAGIRATINGLSMFNDRPCQSCDIIVQAERDLKLSIELLDVKLCMIGNHQLH 344

Query: 350  NXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLDGA 171
            N          LR QGWKISD ++RAGLE+T L+GR+QFLTSK+AE LGLPGATIL+DGA
Sbjct: 345  NALTATCAALCLRDQGWKISDGSVRAGLENTCLVGRTQFLTSKQAELLGLPGATILVDGA 404

Query: 170  HTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            HTKESAKAL DTIQMTFP+ARL LVVAMA DKDH+AFA+E LS R+LD+VILTE
Sbjct: 405  HTKESAKALVDTIQMTFPQARLALVVAMAIDKDHLAFAKEFLSGRKLDSVILTE 458


>ref|XP_012090121.1| dihydrofolate synthetase [Jatropha curcas]
          Length = 557

 Score =  572 bits (1475), Expect = 0.0
 Identities = 292/418 (69%), Positives = 336/418 (80%)
 Frame = -1

Query: 1262 FNRGFSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQ 1083
            FN+ FS   E+ +LKEF DYL +LKNYEKSG+P GAGTDS+DGFD            NPQ
Sbjct: 34   FNKLFSTYMEEPELKEFIDYLGSLKNYEKSGIPKGAGTDSDDGFDLSRMRRLMNHLDNPQ 93

Query: 1082 SKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKS 903
            SKFKA+H+AGTKGKGSTAAFLSNILRAEGYSVGCYTSPHI T+RE +S+G+L EPVSAK+
Sbjct: 94   SKFKAIHIAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIVTVRERMSIGKLGEPVSAKA 153

Query: 902  LNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNI 723
            LNC F RI+  LD+AV+LENG +SHFEVLTA+AF LFA ENID+A+IE GLGGARDATNI
Sbjct: 154  LNCHFHRIRQKLDEAVQLENGCLSHFEVLTAIAFSLFAQENIDIAIIETGLGGARDATNI 213

Query: 722  ISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGK 543
            I SSGLAASVIT+IGEEHL ALGGSLE+IAMAKAGIIK  RP+VLGGPFL  +EHILR K
Sbjct: 214  ICSSGLAASVITSIGEEHLMALGGSLETIAMAKAGIIKHNRPVVLGGPFLPHIEHILREK 273

Query: 542  ASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGP 363
            AS M +PVVSASD   R+ IKG++   G+ CQ CDI++ +DRD +LF +L  + +CMLG 
Sbjct: 274  ASQMNAPVVSASDSETRTTIKGLSMCDGRQCQLCDIIIRVDRDFQLFADLPEIKMCMLGS 333

Query: 362  HQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATIL 183
            HQLQN          LR+QGW ISD +IR G+E+T L GRSQFL SKEAEALGLPGAT+L
Sbjct: 334  HQLQNAATAACAALCLRNQGWGISDRSIRVGIENTCLPGRSQFLASKEAEALGLPGATVL 393

Query: 182  LDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            LDGAHT+ESAKAL DTIQMTFPKA L LVVAMASDKDH+AFARE    + L AV LTE
Sbjct: 394  LDGAHTRESAKALVDTIQMTFPKATLALVVAMASDKDHLAFAREFFLGKNLGAVFLTE 451


>ref|XP_022006741.1| dihydrofolate synthetase [Helianthus annuus]
 ref|XP_022006742.1| dihydrofolate synthetase [Helianthus annuus]
 gb|OTG00012.1| putative folylpolyglutamate synthetase family protein [Helianthus
            annuus]
          Length = 551

 Score =  572 bits (1473), Expect = 0.0
 Identities = 297/414 (71%), Positives = 347/414 (83%)
 Frame = -1

Query: 1244 VLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSKFKAV 1065
            + +E+ +LKEF DYL+NLKN+EKSGVP GAGTDS+DGFD           GNPQSK+K +
Sbjct: 39   ISEEESELKEFNDYLNNLKNHEKSGVPKGAGTDSDDGFDLGRMKRLMQSLGNPQSKYKVI 98

Query: 1064 HVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLNCLFQ 885
            HVAGTKGKGSTAAF+SNILRAEGYSVGCYTSPHI+TIRE I+VG+L  PVSAK++N LFQ
Sbjct: 99   HVAGTKGKGSTAAFVSNILRAEGYSVGCYTSPHIKTIRERITVGKLGNPVSAKAVNSLFQ 158

Query: 884  RIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIISSSGL 705
            RIK +LDQAV+LE+G++SHFEVLTAVAF LFA+EN+ +AVIEAGLGGARDATNIISSS L
Sbjct: 159  RIKVVLDQAVQLEHGHLSHFEVLTAVAFNLFAEENVHIAVIEAGLGGARDATNIISSSDL 218

Query: 704  AASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKASLMGS 525
            AASVITTI EEHLAALGGSLESIA+AK+GIIK G P+VLGGP+L  +E ILR KAS M S
Sbjct: 219  AASVITTISEEHLAALGGSLESIAVAKSGIIKHGCPVVLGGPYLPHIELILRNKASSMCS 278

Query: 524  PVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQLQNX 345
            PV+SASD GN+SIIKG +N+ G P Q  DI+L+I +D +L IEL +V L +LG HQLQN 
Sbjct: 279  PVISASDFGNKSIIKGFSNVSGIPFQLSDIILDIVKDFQLSIELCDVKLRLLGLHQLQNA 338

Query: 344  XXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLDGAHT 165
                     LRHQGW+ISD +IR GLE T LLGRSQFLTS EAE+LGLPGATILLDGAHT
Sbjct: 339  ATATCAALCLRHQGWRISDESIRTGLESTQLLGRSQFLTSVEAESLGLPGATILLDGAHT 398

Query: 164  KESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTEVS 3
            KESAKALAD IQ+T+P A+L+ VVAMASDKDH AFARELL+V+Q++A+ LTEVS
Sbjct: 399  KESAKALADMIQLTYPDAKLVFVVAMASDKDHQAFARELLAVKQVNAIFLTEVS 452


>gb|KVI10194.1| Folylpolyglutamate synthetase [Cynara cardunculus var. scolymus]
          Length = 556

 Score =  571 bits (1472), Expect = 0.0
 Identities = 299/419 (71%), Positives = 348/419 (83%), Gaps = 2/419 (0%)
 Frame = -1

Query: 1256 RGFS--VLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQ 1083
            R FS  +  E+ ++K+F  YLDNLKN+EKSGVP GAGTDS+DGFD           GNPQ
Sbjct: 36   RNFSEMISDEESEMKDFNAYLDNLKNHEKSGVPRGAGTDSDDGFDLGRMKRLMQSLGNPQ 95

Query: 1082 SKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKS 903
            +KFKA+H+AGTKGKGSTAAFLSNI+RAEGYSVGCYTSPHI+TIRE I++GRL +PVSAK+
Sbjct: 96   AKFKAIHIAGTKGKGSTAAFLSNIVRAEGYSVGCYTSPHIKTIRERITLGRLGDPVSAKT 155

Query: 902  LNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNI 723
            +N LFQRIK +LDQAV+LE G ++HFEVLTAVAF LFA+EN+++AVIEAGLGGARDATN+
Sbjct: 156  VNSLFQRIKVVLDQAVQLEMGCLTHFEVLTAVAFNLFAEENVEIAVIEAGLGGARDATNV 215

Query: 722  ISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGK 543
            ISSS LAASVITTIGEEHLAALGGSLESIA+AK+GIIK GRP+VLGG +L  +E IL  K
Sbjct: 216  ISSSDLAASVITTIGEEHLAALGGSLESIAIAKSGIIKYGRPVVLGGSYLPHIELILCNK 275

Query: 542  ASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGP 363
            AS M SPV+S SDP NRS IKGI+NI G+PCQ CDI+L  +RD+ L IEL +V L MLG 
Sbjct: 276  ASSMCSPVISVSDPKNRSKIKGISNISGRPCQVCDIILHAERDLPLCIELYDVKLRMLGW 335

Query: 362  HQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATIL 183
            HQLQN          LR QGW+ISD +IR GLE T LLGRSQFLTS EAEALGLPGATIL
Sbjct: 336  HQLQNAATGTCAALCLRDQGWRISDESIRTGLERTQLLGRSQFLTSVEAEALGLPGATIL 395

Query: 182  LDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTEV 6
            LDGAHTKESAKALA+ IQ+T P+A+L+ VVAMASDKDH AFA+E+L+VRQ DAV+LTEV
Sbjct: 396  LDGAHTKESAKALANMIQITHPEAQLVFVVAMASDKDHRAFAKEILAVRQPDAVLLTEV 454


>dbj|GAV66233.1| Mur_ligase_M domain-containing protein [Cephalotus follicularis]
          Length = 549

 Score =  570 bits (1469), Expect = 0.0
 Identities = 296/415 (71%), Positives = 344/415 (82%)
 Frame = -1

Query: 1247 SVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSKFKA 1068
            +V  ED++L++   Y+D+L NYEKSG P  AGTDS+ GFD           GNP S FKA
Sbjct: 31   AVAAEDRELEDLIGYMDSLNNYEKSGFPKDAGTDSDHGFDLGRMTRLMDRLGNPHSNFKA 90

Query: 1067 VHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLNCLF 888
            +H+AGTKGKGSTAAFLSNILRA+GYSVGCYTSPHI TIRE I VGR SEPVSAK+LNCLF
Sbjct: 91   IHIAGTKGKGSTAAFLSNILRAQGYSVGCYTSPHIMTIRERILVGRSSEPVSAKALNCLF 150

Query: 887  QRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIISSSG 708
            + I+ ILDQA+E+EN  ++HFEV TA+AF LFA EN+D+AVIEAGLGGARDATNIIS  G
Sbjct: 151  RNIRPILDQALEVENRCLTHFEVFTAIAFALFAQENVDIAVIEAGLGGARDATNIISRIG 210

Query: 707  LAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKASLMG 528
            LAASVITTIGEEHLAALGGSLESIA+AK+GIIK GRPL+LGGPFL  +EHILR KASLM 
Sbjct: 211  LAASVITTIGEEHLAALGGSLESIAVAKSGIIKHGRPLILGGPFLPHIEHILREKASLMC 270

Query: 527  SPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQLQN 348
            SPVVSASD G R+ IK I+ +  +PCQSCDI+++++RD +L ++L +VNL MLG HQLQN
Sbjct: 271  SPVVSASDAGVRTTIKRISMLNDRPCQSCDIMIQVERDRELLLKLNDVNLRMLGSHQLQN 330

Query: 347  XXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLDGAH 168
                      L+ QGW+IS  +IRAGLE+TYLLGRSQFLTSKEAEALGLPGATILLDGAH
Sbjct: 331  AVTAACAALCLQDQGWRISVESIRAGLENTYLLGRSQFLTSKEAEALGLPGATILLDGAH 390

Query: 167  TKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTEVS 3
            TK+SAKAL D IQMTFP+ARL+LVVAMASDKDH+AFARE LS RQL+AV+LTE S
Sbjct: 391  TKDSAKALVDMIQMTFPQARLVLVVAMASDKDHLAFAREFLSGRQLEAVLLTEAS 445


>ref|XP_024046876.1| dihydrofolate synthetase isoform X2 [Citrus clementina]
          Length = 451

 Score =  563 bits (1451), Expect = 0.0
 Identities = 289/408 (70%), Positives = 337/408 (82%)
 Frame = -1

Query: 1250 FSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSKFK 1071
            FS   E+ +L  F +YLD+LKN+EKSGVP GAGTDS+DGFD           GNP SKFK
Sbjct: 36   FSTSSEEPELMNFMNYLDSLKNFEKSGVPKGAGTDSDDGFDLGRMNRLMDRLGNPHSKFK 95

Query: 1070 AVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLNCL 891
             VH+AGTKGKGSTAAFLS+ILRAEGYSVGCYTSPHI+TIRE ++VGRL+ PVSAK+LNCL
Sbjct: 96   TVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCL 155

Query: 890  FQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIISSS 711
            F +IK +LD+A+ LENG I+HFEVLTA+AF LFA  ++D+AVIEAGLGGARDATNIISSS
Sbjct: 156  FHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARDATNIISSS 215

Query: 710  GLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKASLM 531
            GLAASVITTIGEEH AALGGSLE+IAMAK+GIIK GRPLVLGGPFL  +EHILR +ASLM
Sbjct: 216  GLAASVITTIGEEHTAALGGSLETIAMAKSGIIKYGRPLVLGGPFLPHIEHILRDEASLM 275

Query: 530  GSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQLQ 351
             S VVSA D G R+ I G++    +PCQSCDI+++ +RD+KL IELL+V LCM+G HQL 
Sbjct: 276  CSQVVSAYDAGIRATINGLSMFNDRPCQSCDIIVQAERDLKLSIELLDVKLCMIGNHQLH 335

Query: 350  NXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLDGA 171
            N          LR QGWKISD ++RAGLE+T L+GR+QFLTSK+AE LGLPGATIL+DGA
Sbjct: 336  NALTATCAALCLRDQGWKISDGSVRAGLENTCLVGRTQFLTSKQAELLGLPGATILVDGA 395

Query: 170  HTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLD 27
            HTKESAKAL DTIQMTFP+ARL LVVAMA DKDH+AFA+E LSV  +D
Sbjct: 396  HTKESAKALVDTIQMTFPQARLALVVAMAIDKDHLAFAKEFLSVGHID 443


>ref|XP_007038953.2| PREDICTED: dihydrofolate synthetase isoform X2 [Theobroma cacao]
          Length = 549

 Score =  567 bits (1460), Expect = 0.0
 Identities = 292/414 (70%), Positives = 341/414 (82%)
 Frame = -1

Query: 1250 FSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSKFK 1071
            FS   E+ +LK+F  Y+D+LKNYEKSGVP  AGTDS+DGFD           GNPQS FK
Sbjct: 30   FSTYTEEPELKDFIQYIDSLKNYEKSGVPKDAGTDSDDGFDLGRMRRLMDRLGNPQSNFK 89

Query: 1070 AVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLNCL 891
            +VH+AGTKGKGSTAA+LSNILR EGYSVGCYTSPHI +IRE +SVGRL +PVS+K+LNCL
Sbjct: 90   SVHIAGTKGKGSTAAYLSNILRTEGYSVGCYTSPHILSIRERMSVGRLGKPVSSKTLNCL 149

Query: 890  FQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIISSS 711
            F+RIK  LD+A+ LENG +SHFEVLTAVAF LFA EN+D+A+IEAGLGGARDATNIISSS
Sbjct: 150  FRRIKQSLDEAIILENGCLSHFEVLTAVAFTLFAQENVDIAIIEAGLGGARDATNIISSS 209

Query: 710  GLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKASLM 531
             LAAS+ITTIGEEHLAALGGSLESIAMAKAGIIK GRPL+LGGPFL  ++ ILR KA  M
Sbjct: 210  ELAASIITTIGEEHLAALGGSLESIAMAKAGIIKHGRPLILGGPFLPHIDCILRDKALSM 269

Query: 530  GSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQLQ 351
             SP+VSASD G R+ IKG++   G+P QSCD+++++D D +L IEL ++NL MLG HQLQ
Sbjct: 270  SSPIVSASDSGIRTAIKGVSTFKGRPSQSCDLMIQLDCDFQLSIELCDLNLSMLGTHQLQ 329

Query: 350  NXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLDGA 171
            N          L +QGWKISD +IRAGLE+T L GRSQFLTSKEAE LGLPGAT+L+DGA
Sbjct: 330  NAVTAACTALCLCNQGWKISDGSIRAGLENTCLQGRSQFLTSKEAETLGLPGATVLIDGA 389

Query: 170  HTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            HTKESAKAL DTIQMTFP +RL +VVAMA DKDH+AFA+ELLS RQ++AV LTE
Sbjct: 390  HTKESAKALLDTIQMTFPDSRLAIVVAMACDKDHLAFAKELLSGRQVEAVFLTE 443


>ref|XP_023740748.1| dihydrofolate synthetase isoform X1 [Lactuca sativa]
 gb|PLY68506.1| hypothetical protein LSAT_2X134221 [Lactuca sativa]
          Length = 550

 Score =  567 bits (1460), Expect = 0.0
 Identities = 298/422 (70%), Positives = 347/422 (82%), Gaps = 2/422 (0%)
 Frame = -1

Query: 1262 FNRGFSVL--QEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGN 1089
            F   FS L  +E+ +LKEF DYLDNLKN+EKSGVP GAGTDS+DGFD           GN
Sbjct: 34   FKHKFSGLISEEESELKEFNDYLDNLKNHEKSGVPKGAGTDSDDGFDLGRMKRLMQSLGN 93

Query: 1088 PQSKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSA 909
            PQSKFKAVH+AGTKGKGSTAAFLSNILRA+GYSVGCYTSPHI+TIRE I++GRL +PVSA
Sbjct: 94   PQSKFKAVHIAGTKGKGSTAAFLSNILRAQGYSVGCYTSPHIKTIRERITLGRLGDPVSA 153

Query: 908  KSLNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDAT 729
            K++N LFQRIK +LDQAV+LE G++SHFEVLTAVAF LFA+EN+D+AVIEAGLGGARDAT
Sbjct: 154  KTVNSLFQRIKLVLDQAVQLEKGHLSHFEVLTAVAFNLFAEENVDIAVIEAGLGGARDAT 213

Query: 728  NIISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILR 549
            NIIS S +A S+ITTIGEEH+AALGGSLE+I +AK+GIIK GRP+VLGGP+L  +E ILR
Sbjct: 214  NIISGSDVAVSIITTIGEEHVAALGGSLETITVAKSGIIKHGRPVVLGGPYLPHIELILR 273

Query: 548  GKASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCML 369
             KAS   SPV+SASDPGN S+IKGI N+ G P Q  DI+L I+RD++L  E  +V L +L
Sbjct: 274  NKASSCCSPVISASDPGNTSVIKGITNVSGIPFQVSDIILHINRDLQLCFEAYDVKLRLL 333

Query: 368  GPHQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGAT 189
            G HQLQN          LR QGW+ISD +IR+GLE T+LLGRSQFLTS+E EALGLPGAT
Sbjct: 334  GWHQLQNAATATCAALCLRDQGWRISDGSIRSGLEITHLLGRSQFLTSEEIEALGLPGAT 393

Query: 188  ILLDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            ILLDGAHTKESAKALAD IQ+T P+A L+ VVAMASDKDH AFA ELL+VR+  AV+LTE
Sbjct: 394  ILLDGAHTKESAKALADMIQITSPEAALVFVVAMASDKDHQAFATELLAVRRPVAVLLTE 453

Query: 8    VS 3
            VS
Sbjct: 454  VS 455


>ref|XP_008234781.1| PREDICTED: dihydrofolate synthetase [Prunus mume]
          Length = 556

 Score =  567 bits (1460), Expect = 0.0
 Identities = 293/418 (70%), Positives = 340/418 (81%)
 Frame = -1

Query: 1256 RGFSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSK 1077
            RGF    +D +LK+  +Y+++LKNYEKSGVP  AGTDSEDGFD           GNP SK
Sbjct: 34   RGFCASSDDLELKDLMEYMNSLKNYEKSGVPKDAGTDSEDGFDLGRMRRLLELLGNPHSK 93

Query: 1076 FKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLN 897
            FKAVH+AGTKGKGSTAAFLS+ILRAEG+SVGCYTSPHIQT+RE IS+GR  EPVSAK+L 
Sbjct: 94   FKAVHIAGTKGKGSTAAFLSSILRAEGHSVGCYTSPHIQTVRERISMGRFGEPVSAKALR 153

Query: 896  CLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIIS 717
             LF RIK ILD+A+E+ENG +SHFEVLTA+AF LFA EN+ +AVIEAGLGGARDATN+I 
Sbjct: 154  SLFHRIKKILDRAMEVENGRMSHFEVLTAMAFTLFAQENVGIAVIEAGLGGARDATNVIC 213

Query: 716  SSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKAS 537
            SSGLA SVITTIGEEHLAALGGSLESIA AK+GIIK GRP+VLGGPFL ++EHILR KA 
Sbjct: 214  SSGLATSVITTIGEEHLAALGGSLESIATAKSGIIKHGRPVVLGGPFLPRIEHILRDKAF 273

Query: 536  LMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQ 357
            LM SPVV ASD GNRS I G++ + G+P QSCDIV+ ++RD+KLFIELL+V L MLG HQ
Sbjct: 274  LMSSPVVLASDSGNRSKINGVSMLNGRPFQSCDIVIRVERDLKLFIELLDVKLYMLGTHQ 333

Query: 356  LQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLD 177
            LQN          LRH GW+ISD  IR GL+ T+LLGRSQFLTSKEA+A+GL GATILLD
Sbjct: 334  LQNAVTATCAALCLRHLGWRISDECIRTGLQQTHLLGRSQFLTSKEAQAIGLSGATILLD 393

Query: 176  GAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTEVS 3
            GAHTKESA+AL +TI+MTFP+A L LVVAMASDKDH+ FARE LS   ++ V+L E S
Sbjct: 394  GAHTKESARALMETIKMTFPEAGLTLVVAMASDKDHLGFARECLSGGHVNGVVLMEAS 451


>gb|KDP22174.1| hypothetical protein JCGZ_26005 [Jatropha curcas]
          Length = 516

 Score =  565 bits (1456), Expect = 0.0
 Identities = 288/409 (70%), Positives = 331/409 (80%)
 Frame = -1

Query: 1235 EDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSKFKAVHVA 1056
            E+ +LKEF DYL +LKNYEKSG+P GAGTDS+DGFD            NPQSKFKA+H+A
Sbjct: 2    EEPELKEFIDYLGSLKNYEKSGIPKGAGTDSDDGFDLSRMRRLMNHLDNPQSKFKAIHIA 61

Query: 1055 GTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLNCLFQRIK 876
            GTKGKGSTAAFLSNILRAEGYSVGCYTSPHI T+RE +S+G+L EPVSAK+LNC F RI+
Sbjct: 62   GTKGKGSTAAFLSNILRAEGYSVGCYTSPHIVTVRERMSIGKLGEPVSAKALNCHFHRIR 121

Query: 875  TILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIISSSGLAAS 696
              LD+AV+LENG +SHFEVLTA+AF LFA ENID+A+IE GLGGARDATNII SSGLAAS
Sbjct: 122  QKLDEAVQLENGCLSHFEVLTAIAFSLFAQENIDIAIIETGLGGARDATNIICSSGLAAS 181

Query: 695  VITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKASLMGSPVV 516
            VIT+IGEEHL ALGGSLE+IAMAKAGIIK  RP+VLGGPFL  +EHILR KAS M +PVV
Sbjct: 182  VITSIGEEHLMALGGSLETIAMAKAGIIKHNRPVVLGGPFLPHIEHILREKASQMNAPVV 241

Query: 515  SASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQLQNXXXX 336
            SASD   R+ IKG++   G+ CQ CDI++ +DRD +LF +L  + +CMLG HQLQN    
Sbjct: 242  SASDSETRTTIKGLSMCDGRQCQLCDIIIRVDRDFQLFADLPEIKMCMLGSHQLQNAATA 301

Query: 335  XXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLDGAHTKES 156
                  LR+QGW ISD +IR G+E+T L GRSQFL SKEAEALGLPGAT+LLDGAHT+ES
Sbjct: 302  ACAALCLRNQGWGISDRSIRVGIENTCLPGRSQFLASKEAEALGLPGATVLLDGAHTRES 361

Query: 155  AKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            AKAL DTIQMTFPKA L LVVAMASDKDH+AFARE    + L AV LTE
Sbjct: 362  AKALVDTIQMTFPKATLALVVAMASDKDHLAFAREFFLGKNLGAVFLTE 410


>ref|XP_021616708.1| dihydrofolate synthetase [Manihot esculenta]
 gb|OAY48411.1| hypothetical protein MANES_06G157100 [Manihot esculenta]
          Length = 559

 Score =  566 bits (1459), Expect = 0.0
 Identities = 291/418 (69%), Positives = 343/418 (82%)
 Frame = -1

Query: 1262 FNRGFSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQ 1083
            F + FS  +++ +LK+F DYLD+LKNYEKSGVP  AGTDS++GFD           GNP 
Sbjct: 36   FKQLFSSYRDEPELKDFVDYLDSLKNYEKSGVPKDAGTDSDEGFDLGRMRRLMDRLGNPH 95

Query: 1082 SKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKS 903
            +KFKA+H+AGTKGKGSTAAFLSNILRAEGYSVGCYTSPHI TIRE +S+G+  EPVSA  
Sbjct: 96   AKFKAIHIAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIMTIRERMSMGKFGEPVSAMV 155

Query: 902  LNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNI 723
            LNC F +I+  LD+A+ LENG +SHFEVLTA AF LFA ENI++AVIEAGLGGARDATNI
Sbjct: 156  LNCHFHQIRQKLDEAIRLENGCLSHFEVLTAFAFSLFAQENINIAVIEAGLGGARDATNI 215

Query: 722  ISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGK 543
            I SSGLAASVIT+IGEEHL ALGGSLESIAMAKAGIIK GRPLVLGGPFL  +E ILR K
Sbjct: 216  ICSSGLAASVITSIGEEHLMALGGSLESIAMAKAGIIKHGRPLVLGGPFLPHIERILRNK 275

Query: 542  ASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGP 363
            ASLM SPVVSASD G R+IIKG++   G+ CQ CDI++++++D +LFIE+ ++ + MLG 
Sbjct: 276  ASLMHSPVVSASDSGIRTIIKGLSMCNGRLCQLCDIMIQVEKDFQLFIEISDLKMHMLGS 335

Query: 362  HQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATIL 183
            HQLQN          LR+QGW+ISD +IR GLE+TYLLGRSQFL SKEAE LGLPGATIL
Sbjct: 336  HQLQNAATAACAALCLRNQGWRISDGSIRFGLENTYLLGRSQFLASKEAEVLGLPGATIL 395

Query: 182  LDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTE 9
            LDGAHTKESAKAL DT++MTFPKAR++LVVAMASDKDH+ FAR+ L  ++L+AV LTE
Sbjct: 396  LDGAHTKESAKALVDTVRMTFPKARMVLVVAMASDKDHLEFARQFLLDKRLEAVFLTE 453


>ref|XP_015389579.1| PREDICTED: dihydrofolate synthetase isoform X1 [Citrus sinensis]
          Length = 563

 Score =  566 bits (1459), Expect = 0.0
 Identities = 295/421 (70%), Positives = 344/421 (81%), Gaps = 7/421 (1%)
 Frame = -1

Query: 1250 FSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQSKFK 1071
            FS   E+ +L  F +YLD+LKN+EKSGVP GAGTDS+DGFD           GNP SKFK
Sbjct: 36   FSTSSEEPELMNFMNYLDSLKNFEKSGVPKGAGTDSDDGFDLGRMNRLMDRLGNPHSKFK 95

Query: 1070 AVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKSLNCL 891
             VH+AGTKGKGSTAAFLS+ILRAEGYSVGCYTSPHI+TIRE ++VGRL+ PVSAK+LNCL
Sbjct: 96   TVHIAGTKGKGSTAAFLSSILRAEGYSVGCYTSPHIKTIRERMNVGRLNRPVSAKALNCL 155

Query: 890  FQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNIISSS 711
            F +IK +LD+A+ LENG I+HFEVLTA+AF LFA  ++D+AVIEAGLGGARDATNIISSS
Sbjct: 156  FHKIKGVLDEAIRLENGCITHFEVLTAMAFALFAQNHVDIAVIEAGLGGARDATNIISSS 215

Query: 710  GLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGKASLM 531
            GLAASVITTIGEEH AALGGSLE+IAMAK+GIIK GRPLVLGGPFL  +EHILR +ASLM
Sbjct: 216  GLAASVITTIGEEHTAALGGSLETIAMAKSGIIKYGRPLVLGGPFLPHIEHILRDEASLM 275

Query: 530  GSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGPHQLQ 351
             S VVSA D G R+ I G++    +PCQSCDI+++ +RD+KL IELL+V LCM+G HQL 
Sbjct: 276  CSQVVSAYDAGIRATINGLSMFNDRPCQSCDIIVQAERDLKLSIELLDVKLCMIGNHQLH 335

Query: 350  NXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATILLDG- 174
            N          LR QGWKISD ++RAGLE+T L+GR+QFLTSK+AE LGLPGATIL+DG 
Sbjct: 336  NALTATCAALCLRDQGWKISDGSVRAGLENTCLVGRTQFLTSKQAELLGLPGATILVDGG 395

Query: 173  ------AHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILT 12
                  AHTKESAKAL DTIQMTFP+ARL LVVAMA DKDH+AFA+E LS R+LD+VILT
Sbjct: 396  DFYSFVAHTKESAKALVDTIQMTFPQARLALVVAMAIDKDHLAFAKEFLSGRKLDSVILT 455

Query: 11   E 9
            E
Sbjct: 456  E 456


>ref|XP_010249972.1| PREDICTED: dihydrofolate synthetase isoform X2 [Nelumbo nucifera]
          Length = 555

 Score =  565 bits (1457), Expect = 0.0
 Identities = 297/419 (70%), Positives = 339/419 (80%)
 Frame = -1

Query: 1262 FNRGFSVLQEDQDLKEFTDYLDNLKNYEKSGVPIGAGTDSEDGFDXXXXXXXXXXXGNPQ 1083
            F RG S   ED +LKEF DYL+NLKNYEKSGVP GAGTDSEDGFD           GNPQ
Sbjct: 32   FRRGVSTYSEDLELKEFLDYLENLKNYEKSGVPKGAGTDSEDGFDLGRMNRLMERLGNPQ 91

Query: 1082 SKFKAVHVAGTKGKGSTAAFLSNILRAEGYSVGCYTSPHIQTIRECISVGRLSEPVSAKS 903
            SKFKAVH+AGTKGKGSTAAFLSN+LR EGYSVGCYTSPH+ +IRE ISVGR S+PVSAK+
Sbjct: 92   SKFKAVHIAGTKGKGSTAAFLSNMLREEGYSVGCYTSPHLWSIRERISVGRKSDPVSAKA 151

Query: 902  LNCLFQRIKTILDQAVELENGYISHFEVLTAVAFRLFADENIDVAVIEAGLGGARDATNI 723
            LN +F   K ILDQ++ELENG ISHFEV TA+AF LFA E +D+AV+EAGLGGARDATN+
Sbjct: 152  LNSVFHWAKEILDQSMELENGSISHFEVFTALAFTLFAQEKVDIAVVEAGLGGARDATNV 211

Query: 722  ISSSGLAASVITTIGEEHLAALGGSLESIAMAKAGIIKSGRPLVLGGPFLSKVEHILRGK 543
              SSGLAA++ITTIGEEHLAALGGSLESIAMAK+GIIK G PLVLGGPF   +E ILR K
Sbjct: 212  FCSSGLAAAIITTIGEEHLAALGGSLESIAMAKSGIIKHGCPLVLGGPFNPHIECILRDK 271

Query: 542  ASLMGSPVVSASDPGNRSIIKGINNICGKPCQSCDIVLEIDRDIKLFIELLNVNLCMLGP 363
            AS M SPVVSA DPGN S IKG      KPCQ CDIV++I++D++LFIEL +V L MLG 
Sbjct: 272  ASSMDSPVVSAFDPGNLSRIKGFEINKEKPCQLCDIVVQIEKDMQLFIELYDVRLHMLGT 331

Query: 362  HQLQNXXXXXXXXXXLRHQGWKISDVAIRAGLEHTYLLGRSQFLTSKEAEALGLPGATIL 183
            HQLQN          LR+QGW+ISD +I AGL+HT+L GRSQFL SKE+E+LG+ GATIL
Sbjct: 332  HQLQNAVTATCAALCLRNQGWRISDESIHAGLQHTFLPGRSQFLASKESESLGIYGATIL 391

Query: 182  LDGAHTKESAKALADTIQMTFPKARLILVVAMASDKDHIAFARELLSVRQLDAVILTEV 6
            LDGAHTKESAK+LADTIQMT+P A  +LVVAMASDKDH+AFARE L+  Q +AVILT+V
Sbjct: 392  LDGAHTKESAKSLADTIQMTYPDAPAVLVVAMASDKDHLAFAREFLTGMQPEAVILTQV 450