BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Acanthopanax21_contig00005447
         (1778 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_017257659.1| PREDICTED: bifunctional dihydrofolate reduct...   945   0.0  
ref|XP_017215083.1| PREDICTED: bifunctional dihydrofolate reduct...   924   0.0  
emb|CAA05895.1| dihydrofolate reductase-thymidylate synthetase p...   908   0.0  
sp|P45350.1|DRTS_DAUCA RecName: Full=Bifunctional dihydrofolate ...   905   0.0  
ref|XP_021662680.1| bifunctional dihydrofolate reductase-thymidy...   905   0.0  
ref|XP_021658747.1| bifunctional dihydrofolate reductase-thymidy...   905   0.0  
gb|KZN11004.1| hypothetical protein DCAR_003660 [Daucus carota s...   903   0.0  
ref|XP_002280254.1| PREDICTED: bifunctional dihydrofolate reduct...   892   0.0  
gb|KZM89650.1| hypothetical protein DCAR_022987 [Daucus carota s...   888   0.0  
ref|XP_021628142.1| bifunctional dihydrofolate reductase-thymidy...   887   0.0  
gb|OMO75612.1| Thymidylate synthase [Corchorus olitorius]             887   0.0  
gb|OMO74316.1| Thymidylate synthase [Corchorus capsularis]            886   0.0  
ref|XP_021285499.1| bifunctional dihydrofolate reductase-thymidy...   886   0.0  
ref|XP_007042127.2| PREDICTED: bifunctional dihydrofolate reduct...   886   0.0  
ref|XP_011037491.1| PREDICTED: bifunctional dihydrofolate reduct...   884   0.0  
ref|XP_010254750.1| PREDICTED: putative bifunctional dihydrofola...   884   0.0  
ref|XP_010254749.1| PREDICTED: putative bifunctional dihydrofola...   884   0.0  
gb|EOX97956.1| Thymidylate synthase 1 isoform 1 [Theobroma cacao...   884   0.0  
ref|XP_006384511.1| hypothetical protein POPTR_0004s16470g [Popu...   883   0.0  
ref|XP_010254751.1| PREDICTED: putative bifunctional dihydrofola...   882   0.0  

>ref|XP_017257659.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
 ref|XP_017257740.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
          Length = 576

 Score =  945 bits (2442), Expect = 0.0
 Identities = 448/517 (86%), Positives = 484/517 (93%), Gaps = 2/517 (0%)
 Frame = +3

Query: 234  CQPLISLMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFF 413
            C    + MA + L +  NGSGIT  DPQRTYQVVVAATQNMGIGKDGK+PWRLPSD+KFF
Sbjct: 43   CHRFTTYMASEALANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFF 102

Query: 414  KDITMTTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGS 593
            KD+TMTTSDP+K+NAVIMGRKTWESIP++HRPLP RLNVVLTRSGSFDIAT ENVVICGS
Sbjct: 103  KDVTMTTSDPLKRNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGS 162

Query: 594  MVSALELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLD 773
            M+SALELLA SPYCVS+EKVFVIGGGQIYREALNAPGCDA+HIT+IEE IECDTFIP LD
Sbjct: 163  MISALELLAGSPYCVSVEKVFVIGGGQIYREALNAPGCDAVHITEIEEHIECDTFIPLLD 222

Query: 774  ESVFQPWYSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSF 947
            ESVFQPWYSS PLVEN IRYCFTTYVRVR+S  E   QTNGLSSD+ SDSG FEIQ FSF
Sbjct: 223  ESVFQPWYSSFPLVENKIRYCFTTYVRVRNSVAELTSQTNGLSSDSKSDSGNFEIQNFSF 282

Query: 948  LPKKIFEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKV 1127
            LPK +FEKHEEY+YL +VENI+SNGV+K+DRTRTGT+SIFGCQMRFNLRKSFPLLTTKKV
Sbjct: 283  LPKTVFEKHEEYLYLGLVENIISNGVTKNDRTRTGTVSIFGCQMRFNLRKSFPLLTTKKV 342

Query: 1128 FWRGVVEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQW 1307
            FWRGVVEELLWFISGSTNAK+L+EKG++IWEGNGSR+YLDSIGL DREEGDLGPIYGFQW
Sbjct: 343  FWRGVVEELLWFISGSTNAKILKEKGVNIWEGNGSREYLDSIGLTDREEGDLGPIYGFQW 402

Query: 1308 RHFGARYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFA 1487
            RHFGARYTDMHADY+GQGFDQLLDV+SKIKNNPDDRRIILSAWNPSDL+LMALPPCHMFA
Sbjct: 403  RHFGARYTDMHADYSGQGFDQLLDVISKIKNNPDDRRIILSAWNPSDLRLMALPPCHMFA 462

Query: 1488 QFYVAKGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYC 1667
            QFYVA GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+H+IGDAHVYC
Sbjct: 463  QFYVANGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHSIGDAHVYC 522

Query: 1668 THVRPLQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
             HVRPL++QLQKLPKPFP+LKINSEKRDIDSF AADF
Sbjct: 523  NHVRPLRDQLQKLPKPFPVLKINSEKRDIDSFEAADF 559


>ref|XP_017215083.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
 ref|XP_017215084.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
 ref|XP_017215085.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Daucus carota subsp. sativus]
          Length = 527

 Score =  924 bits (2389), Expect = 0.0
 Identities = 442/510 (86%), Positives = 477/510 (93%), Gaps = 2/510 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITMTT 434
            MA +TL +  NGS IT ++PQRTYQVVVAATQNMGIGKDG +PW LPSDLKFFKD+TMTT
Sbjct: 1    MASETLTNPTNGSVITSSNPQRTYQVVVAATQNMGIGKDGSLPWSLPSDLKFFKDVTMTT 60

Query: 435  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSALEL 614
            SDP+K+NAVIMGRKTWESIPL+HRPLP R NVVLTRSGSFDIATAENVVICGS++SALEL
Sbjct: 61   SDPLKRNAVIMGRKTWESIPLQHRPLPGRFNVVLTRSGSFDIATAENVVICGSLLSALEL 120

Query: 615  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 794
            LA SPYCVSIEKVFVIGGGQIYREALNAPGCDA+HIT+I + IECDTFIP LDESVFQPW
Sbjct: 121  LAESPYCVSIEKVFVIGGGQIYREALNAPGCDAVHITEIGKHIECDTFIPALDESVFQPW 180

Query: 795  YSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 968
            YSS P+VENNIRYCFTTYVRVR+S VE   + NGL SD NSDSGKFE+Q+FSFLPK +FE
Sbjct: 181  YSSFPVVENNIRYCFTTYVRVRNSGVELASEANGLLSDGNSDSGKFEVQRFSFLPKPVFE 240

Query: 969  KHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 1148
            KH+EY+YLR+VENI+ NGV K+DRTRTGT+S+FGCQMRFNLRKSFPLLTTKKVFWRGVVE
Sbjct: 241  KHQEYLYLRLVENIILNGVEKNDRTRTGTVSMFGCQMRFNLRKSFPLLTTKKVFWRGVVE 300

Query: 1149 ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1328
            ELLWFISGSTNAKVL+EKGI+IWEGNGSRDYLDSIGL  REEGDLGPIYGFQWRHFGARY
Sbjct: 301  ELLWFISGSTNAKVLKEKGINIWEGNGSRDYLDSIGLTHREEGDLGPIYGFQWRHFGARY 360

Query: 1329 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1508
            TDMHADYTGQGFDQL DV+SKIK NPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA G
Sbjct: 361  TDMHADYTGQGFDQLQDVISKIKENPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 420

Query: 1509 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1688
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+HTIGDAH+Y  HVRPLQ
Sbjct: 421  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHTIGDAHIYLNHVRPLQ 480

Query: 1689 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            +QLQKLPKPFP+LKINSEKR+IDSF AADF
Sbjct: 481  DQLQKLPKPFPVLKINSEKRNIDSFEAADF 510


>emb|CAA05895.1| dihydrofolate reductase-thymidylate synthetase precursor [Daucus
            carota]
          Length = 577

 Score =  908 bits (2346), Expect = 0.0
 Identities = 434/518 (83%), Positives = 473/518 (91%), Gaps = 3/518 (0%)
 Frame = +3

Query: 234  CQPLISLMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFF 413
            C    + MA + L +  NGSGIT  DPQRTYQVVVAATQNMGIGKDGK+PWRLPSD+KFF
Sbjct: 43   CHRFTTYMASERLANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFF 102

Query: 414  KDITMTTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGS 593
            KD+TMTTSDP+K+NAVIMGRKTWESIP++HRPLP RLNVVLTRSGSFDIAT ENVVICGS
Sbjct: 103  KDVTMTTSDPLKRNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGS 162

Query: 594  MVSALELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLD 773
            M+SALELLA SPYCVS+EKVFVIGGGQIYREALNAPGCDA+HIT+IEE IECDTFIP LD
Sbjct: 163  MISALELLAGSPYCVSVEKVFVIGGGQIYREALNAPGCDAVHITEIEEHIECDTFIPLLD 222

Query: 774  ESVFQPWYSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSF 947
            ESVFQPWYSS PLVEN IRYCFTTYVRVR+S  E   QTNG SSD+ SDSG FEIQ FSF
Sbjct: 223  ESVFQPWYSSFPLVENKIRYCFTTYVRVRNSVAELTSQTNGCSSDSKSDSGNFEIQNFSF 282

Query: 948  LPKKIFEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKV 1127
            LPK +FEKHEEY+YL +VENI+SNGV+K+DRTRTGT+SIFGCQMRFNLRKSFPLLTTKKV
Sbjct: 283  LPKTVFEKHEEYLYLGLVENIISNGVTKNDRTRTGTVSIFGCQMRFNLRKSFPLLTTKKV 342

Query: 1128 FWRGVVEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQW 1307
            FWRGVVEELLWFISGSTNAK+L+EKG++IWEGNGSR+YLDSIGL DREEGDLGPIYGFQW
Sbjct: 343  FWRGVVEELLWFISGSTNAKILKEKGVNIWEGNGSREYLDSIGLTDREEGDLGPIYGFQW 402

Query: 1308 RHFGARYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFA 1487
            RHFGARYTDMHADY+GQGFDQLLDV+SKIKNNPDDRRII SAWNPSDL+LMALPPCHMFA
Sbjct: 403  RHFGARYTDMHADYSGQGFDQLLDVISKIKNNPDDRRIIQSAWNPSDLRLMALPPCHMFA 462

Query: 1488 QFYVAKGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYC 1667
            QFYVA GELSCQMYQRSADMGLGVPFNIA+YALLTCMIAHVCDLVPGDF+H+IGDAHVY 
Sbjct: 463  QFYVANGELSCQMYQRSADMGLGVPFNIAAYALLTCMIAHVCDLVPGDFVHSIGDAHVYS 522

Query: 1668 THVRPLQE-QLQKLPKPFPILKINSEKRDIDSFVAADF 1778
             H+  L E   + LPK FP+LKINS ++DIDSF AADF
Sbjct: 523  NHLSDLFETSFRMLPKTFPVLKINSGEKDIDSFEAADF 560


>sp|P45350.1|DRTS_DAUCA RecName: Full=Bifunctional dihydrofolate reductase-thymidylate
            synthase; Short=DHFR-TS; Includes: RecName:
            Full=Dihydrofolate reductase; Includes: RecName:
            Full=Thymidylate synthase
 emb|CAA78954.1| dihydrofolate reductase-thymidylate synthetase [Daucus carota]
          Length = 528

 Score =  905 bits (2340), Expect = 0.0
 Identities = 433/511 (84%), Positives = 471/511 (92%), Gaps = 3/511 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITMTT 434
            MA + L +  NGSGIT  DPQRTYQVVVAATQNMGIGKDGK+PWRLPSD+KFFKD+TMTT
Sbjct: 1    MASELLANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFFKDVTMTT 60

Query: 435  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSALEL 614
            SDP+K+NAVIMGRKTWESIP++HRPLP RLNVVLTRSGSFDIAT ENVVICGSM+SALEL
Sbjct: 61   SDPLKRNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGSMISALEL 120

Query: 615  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 794
            LA SPYCVS+EKVFVIGGGQIYREALNAPGCDA+HIT+IEE IECDTFIP LDESVFQPW
Sbjct: 121  LAGSPYCVSVEKVFVIGGGQIYREALNAPGCDAVHITEIEEHIECDTFIPLLDESVFQPW 180

Query: 795  YSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 968
            YSS PLVEN IRYCFTTYVRVR+S  E   QTNG SSD+ SDSG FEIQ FSFLPK +FE
Sbjct: 181  YSSFPLVENKIRYCFTTYVRVRNSVAELTSQTNGCSSDSKSDSGNFEIQNFSFLPKTVFE 240

Query: 969  KHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 1148
            KHEEY+YL +VENI+SNGV+K+DRTRTGT+SIFGCQMRFNLRKSFPLLTTKKVFWRGVVE
Sbjct: 241  KHEEYLYLGLVENIISNGVTKNDRTRTGTVSIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 300

Query: 1149 ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1328
            ELLWFISGSTNAK+L+EKG++IWEGNGSR+YLDSIGL DREEGDLGPIYGFQWRHFGARY
Sbjct: 301  ELLWFISGSTNAKILKEKGVNIWEGNGSREYLDSIGLTDREEGDLGPIYGFQWRHFGARY 360

Query: 1329 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1508
            TDMHADY+GQGFDQLLDV+SKIKNNPDDRRII SAWNPSDL+LMALPPCHMFAQFYVA G
Sbjct: 361  TDMHADYSGQGFDQLLDVISKIKNNPDDRRIIQSAWNPSDLRLMALPPCHMFAQFYVANG 420

Query: 1509 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1688
            ELSCQMYQRSADMGLGVPFNIA+YALLTCMIAHVCDLVPGDF+H+IGDAHVY  H+  L 
Sbjct: 421  ELSCQMYQRSADMGLGVPFNIAAYALLTCMIAHVCDLVPGDFVHSIGDAHVYSNHLSDLF 480

Query: 1689 E-QLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            E   + LPK FP+LKINS ++DIDSF AADF
Sbjct: 481  ETSFRMLPKTFPVLKINSGEKDIDSFEAADF 511


>ref|XP_021662680.1| bifunctional dihydrofolate reductase-thymidylate synthase 1-like
            [Hevea brasiliensis]
          Length = 550

 Score =  905 bits (2338), Expect = 0.0
 Identities = 431/517 (83%), Positives = 472/517 (91%), Gaps = 2/517 (0%)
 Frame = +3

Query: 234  CQPLISLMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFF 413
            C    S+MAGD+  ++ NG+      PQRTYQVVVAAT +MGIGKDGK+PWRLPSDLKFF
Sbjct: 17   CWAFFSIMAGDSKANLSNGNANIQPAPQRTYQVVVAATGDMGIGKDGKLPWRLPSDLKFF 76

Query: 414  KDITMTTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGS 593
            KD+TMTTSD  KKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVV+CGS
Sbjct: 77   KDVTMTTSDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGS 136

Query: 594  MVSALELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLD 773
            + SALELLAASPYC+SIEK +VIGGGQI REALNAPGCDAIHIT+IE  I+CDTFIP +D
Sbjct: 137  LSSALELLAASPYCLSIEKAYVIGGGQILREALNAPGCDAIHITEIETNIDCDTFIPTID 196

Query: 774  ESVFQPWYSSVPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSF 947
             SVFQPWYSS P+VENNIRYCF TYVRVRS+AVE   Q NGLSSD  S++ KFE++KFSF
Sbjct: 197  SSVFQPWYSSFPMVENNIRYCFATYVRVRSTAVESNGQNNGLSSDVGSENSKFEVKKFSF 256

Query: 948  LPKKIFEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKV 1127
            LPK +FE+HEE+ YLR+V++I+S+G+ KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKV
Sbjct: 257  LPKMVFERHEEFFYLRLVQDIISDGILKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKV 316

Query: 1128 FWRGVVEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQW 1307
            FWRGVVEELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQW
Sbjct: 317  FWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQW 376

Query: 1308 RHFGARYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFA 1487
            RHFGARY+DMHADYTGQGFDQLLDV+ KIKNNPDDRRIILSAWNPSDLKLMALPPCHMFA
Sbjct: 377  RHFGARYSDMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFA 436

Query: 1488 QFYVAKGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYC 1667
            QFYVA GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVC+LVPGDF+H  GDAHVYC
Sbjct: 437  QFYVAHGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLVPGDFVHVFGDAHVYC 496

Query: 1668 THVRPLQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            THVRPLQEQLQKLPKPFPILKIN +K++IDSFVAADF
Sbjct: 497  THVRPLQEQLQKLPKPFPILKINPDKKNIDSFVAADF 533


>ref|XP_021658747.1| bifunctional dihydrofolate reductase-thymidylate synthase-like [Hevea
            brasiliensis]
          Length = 550

 Score =  905 bits (2338), Expect = 0.0
 Identities = 431/517 (83%), Positives = 472/517 (91%), Gaps = 2/517 (0%)
 Frame = +3

Query: 234  CQPLISLMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFF 413
            C    S+MAGD+  ++ NG+      PQRTYQVVVAAT +MGIGKDGK+PWRLPSDLKFF
Sbjct: 17   CWAFFSIMAGDSKANLSNGNANIQPAPQRTYQVVVAATGDMGIGKDGKLPWRLPSDLKFF 76

Query: 414  KDITMTTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGS 593
            KD+TMTTSD  KKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVV+CGS
Sbjct: 77   KDVTMTTSDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGS 136

Query: 594  MVSALELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLD 773
            + SALELLAASPYC+SIEK +VIGGGQI REALNAPGCDAIHIT+IE  I+CDTFIP +D
Sbjct: 137  LSSALELLAASPYCLSIEKAYVIGGGQILREALNAPGCDAIHITEIEANIDCDTFIPTID 196

Query: 774  ESVFQPWYSSVPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSF 947
             SVFQPWYSS P+VENNIRYCF TYVRVRS+AVE   Q NGLS+D  S++ KFE++KFSF
Sbjct: 197  SSVFQPWYSSFPMVENNIRYCFATYVRVRSTAVESNGQNNGLSADVGSENSKFEVKKFSF 256

Query: 948  LPKKIFEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKV 1127
            LPK +FE+HEE+ YLR+V++I+S+G+ KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKV
Sbjct: 257  LPKMVFERHEEFFYLRLVQDIISDGILKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKV 316

Query: 1128 FWRGVVEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQW 1307
            FWRGVVEELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQW
Sbjct: 317  FWRGVVEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQW 376

Query: 1308 RHFGARYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFA 1487
            RHFGARY+DMHADYTGQGFDQLLDV+ KIKNNPDDRRIILSAWNPSDLKLMALPPCHMFA
Sbjct: 377  RHFGARYSDMHADYTGQGFDQLLDVIDKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFA 436

Query: 1488 QFYVAKGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYC 1667
            QFYVA GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVC+LVPGDF+H  GDAHVYC
Sbjct: 437  QFYVAHGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLVPGDFVHVFGDAHVYC 496

Query: 1668 THVRPLQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            THVRPLQEQLQKLPKPFPILKIN EK++IDSFVAADF
Sbjct: 497  THVRPLQEQLQKLPKPFPILKINPEKKNIDSFVAADF 533


>gb|KZN11004.1| hypothetical protein DCAR_003660 [Daucus carota subsp. sativus]
          Length = 560

 Score =  903 bits (2334), Expect = 0.0
 Identities = 432/510 (84%), Positives = 467/510 (91%), Gaps = 2/510 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITMTT 434
            MA + L +  NGSGIT  DPQRTYQVVVAATQNMGIGKDGK+PWRLPSD+KFFKD+TMTT
Sbjct: 1    MASEALANPTNGSGITRPDPQRTYQVVVAATQNMGIGKDGKLPWRLPSDMKFFKDVTMTT 60

Query: 435  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSALEL 614
            SDP+K+NAVIMGRKTWESIP++HRPLP RLNVVLTRSGSFDIAT ENVVICGSM+SALEL
Sbjct: 61   SDPLKRNAVIMGRKTWESIPIQHRPLPGRLNVVLTRSGSFDIATVENVVICGSMISALEL 120

Query: 615  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 794
            LA SPYCVS+EKVFVIGGGQIYREALNAPGCDA+HIT+IEE IECDTFIP LDESVFQPW
Sbjct: 121  LAGSPYCVSVEKVFVIGGGQIYREALNAPGCDAVHITEIEEHIECDTFIPLLDESVFQPW 180

Query: 795  YSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 968
            YSS PLVEN IRYCFTTYVRVR+S  E   QTNGLSSD+ SDSG FEIQ FSFLPK +FE
Sbjct: 181  YSSFPLVENKIRYCFTTYVRVRNSVAELTSQTNGLSSDSKSDSGNFEIQNFSFLPKTVFE 240

Query: 969  KHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 1148
            KHEEY+YL +VENI+SNGV+K+DRTRTGT+SIFGCQ               KVFWRGVVE
Sbjct: 241  KHEEYLYLGLVENIISNGVTKNDRTRTGTVSIFGCQ---------------KVFWRGVVE 285

Query: 1149 ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1328
            ELLWFISGSTNAK+L+EKG++IWEGNGSR+YLDSIGL DREEGDLGPIYGFQWRHFGARY
Sbjct: 286  ELLWFISGSTNAKILKEKGVNIWEGNGSREYLDSIGLTDREEGDLGPIYGFQWRHFGARY 345

Query: 1329 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1508
            TDMHADY+GQGFDQLLDV+SKIKNNPDDRRIILSAWNPSDL+LMALPPCHMFAQFYVA G
Sbjct: 346  TDMHADYSGQGFDQLLDVISKIKNNPDDRRIILSAWNPSDLRLMALPPCHMFAQFYVANG 405

Query: 1509 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1688
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+H+IGDAHVYC HVRPL+
Sbjct: 406  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHSIGDAHVYCNHVRPLR 465

Query: 1689 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            +QLQKLPKPFP+LKINSEKRDIDSF AADF
Sbjct: 466  DQLQKLPKPFPVLKINSEKRDIDSFEAADF 495


>ref|XP_002280254.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X1 [Vitis vinifera]
 ref|XP_010645204.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            isoform X1 [Vitis vinifera]
          Length = 524

 Score =  892 bits (2306), Expect = 0.0
 Identities = 430/508 (84%), Positives = 465/508 (91%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITMTT 434
            MA DT++S+PNG+     DPQRTYQVVVAAT++MGIGKDGK+PWRLPSD+K FKDITMT 
Sbjct: 1    MASDTVVSLPNGNANIQPDPQRTYQVVVAATRDMGIGKDGKLPWRLPSDMKIFKDITMTV 60

Query: 435  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSALEL 614
            +D VKKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVVICGSM SALEL
Sbjct: 61   ADTVKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMASALEL 120

Query: 615  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 794
            LAASPYC+SIEKVFVIGGGQI REALNAPGCDAIHIT+IE   ECDTFIP +D  VFQPW
Sbjct: 121  LAASPYCLSIEKVFVIGGGQILREALNAPGCDAIHITEIETSFECDTFIPAIDSLVFQPW 180

Query: 795  YSSVPLVENNIRYCFTTYVRVRSSAVEPQTNGLSSDTNSDSGKFEIQKFSFLPKKIFEKH 974
            YSS PLVENNIRY F TYVRVRSSA E Q    + D+  +S KFE++KFSFLPK IFE+H
Sbjct: 181  YSSFPLVENNIRYSFMTYVRVRSSADESQIQN-NGDSGLESIKFEVKKFSFLPKMIFERH 239

Query: 975  EEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVEEL 1154
            EEY+YLR+VE+I+SNGV +DDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGVVEEL
Sbjct: 240  EEYIYLRLVEDIISNGVQRDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVVEEL 299

Query: 1155 LWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARYTD 1334
            LWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGPIYGFQWRHFGA Y D
Sbjct: 300  LWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLADREEGDLGPIYGFQWRHFGASYID 359

Query: 1335 MHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKGEL 1514
            MHADYTGQGFDQLLDV++KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYV+ GEL
Sbjct: 360  MHADYTGQGFDQLLDVINKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVSHGEL 419

Query: 1515 SCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQEQ 1694
            SCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIH IGD+HVY TH+RPLQEQ
Sbjct: 420  SCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHVIGDSHVYLTHIRPLQEQ 479

Query: 1695 LQKLPKPFPILKINSEKRDIDSFVAADF 1778
            LQKLPKPFPILKIN +K++IDSFVAADF
Sbjct: 480  LQKLPKPFPILKINPQKKNIDSFVAADF 507


>gb|KZM89650.1| hypothetical protein DCAR_022987 [Daucus carota subsp. sativus]
          Length = 518

 Score =  888 bits (2294), Expect = 0.0
 Identities = 427/510 (83%), Positives = 465/510 (91%), Gaps = 2/510 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITMTT 434
            MA +TL +  NGS IT ++PQRTYQVVVAATQNMGIGKDG +PW LPSDLKFFKD+TMTT
Sbjct: 1    MASETLTNPTNGSVITSSNPQRTYQVVVAATQNMGIGKDGSLPWSLPSDLKFFKDVTMTT 60

Query: 435  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSALEL 614
            SDP+K+NAVIMGRKTWESIPL+HRPLP R NVVLTRSGSFDIATAENVVICGS++SALEL
Sbjct: 61   SDPLKRNAVIMGRKTWESIPLQHRPLPGRFNVVLTRSGSFDIATAENVVICGSLLSALEL 120

Query: 615  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 794
            LA SPYCVSIEKVFVIGGGQIYREALNAPGCDA+HIT+I + IECDTFIP LDESVFQPW
Sbjct: 121  LAESPYCVSIEKVFVIGGGQIYREALNAPGCDAVHITEIGKHIECDTFIPALDESVFQPW 180

Query: 795  YSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 968
            YSS P+VENNIRYCFTTYVRVR+S VE   + NGL SD NSDSGKFE+Q+FSFLPK +FE
Sbjct: 181  YSSFPVVENNIRYCFTTYVRVRNSGVELASEANGLLSDGNSDSGKFEVQRFSFLPKPVFE 240

Query: 969  KHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 1148
            KH+EY+YLR+VENI+ NGV K+DRTRTGT+S+FGCQ+          +  +KVFWRGVVE
Sbjct: 241  KHQEYLYLRLVENIILNGVEKNDRTRTGTVSMFGCQL---------FVIGQKVFWRGVVE 291

Query: 1149 ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1328
            ELLWFISGSTNAKVL+EKGI+IWEGNGSRDYLDSIGL  REEGDLGPIYGFQWRHFGARY
Sbjct: 292  ELLWFISGSTNAKVLKEKGINIWEGNGSRDYLDSIGLTHREEGDLGPIYGFQWRHFGARY 351

Query: 1329 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1508
            TDMHADYTGQGFDQL DV+SKIK NPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA G
Sbjct: 352  TDMHADYTGQGFDQLQDVISKIKENPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 411

Query: 1509 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1688
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+HTIGDAH+Y  HVRPLQ
Sbjct: 412  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHTIGDAHIYLNHVRPLQ 471

Query: 1689 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            +QLQKLPKPFP+LKINSEKR+IDSF AADF
Sbjct: 472  DQLQKLPKPFPVLKINSEKRNIDSFEAADF 501


>ref|XP_021628142.1| bifunctional dihydrofolate reductase-thymidylate synthase-like
            isoform X1 [Manihot esculenta]
 gb|OAY37221.1| hypothetical protein MANES_11G084400 [Manihot esculenta]
          Length = 527

 Score =  887 bits (2292), Expect = 0.0
 Identities = 425/510 (83%), Positives = 467/510 (91%), Gaps = 2/510 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITMTT 434
            MAG+   ++ NG+       QRTYQVVVAAT++MGIGKDGK+PWRLPSDLKFFKD+TMTT
Sbjct: 1    MAGEFKANLSNGNANVQPAAQRTYQVVVAATRDMGIGKDGKLPWRLPSDLKFFKDVTMTT 60

Query: 435  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSALEL 614
            SD  KKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVV+CGS+ SALEL
Sbjct: 61   SDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVMCGSLNSALEL 120

Query: 615  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 794
            LAASPYC+SIEK FVIGGGQI REALNAPGCDAIH+T+IE  I+CDTFIP +D SVFQPW
Sbjct: 121  LAASPYCLSIEKAFVIGGGQILREALNAPGCDAIHMTEIETNIDCDTFIPTVDSSVFQPW 180

Query: 795  YSSVPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 968
            YSS P+VEN+IRYCF TYVRVRSS VE   + NGLSSD+ S++ KFE++KFSFLPK +FE
Sbjct: 181  YSSFPMVENSIRYCFATYVRVRSSVVESNGENNGLSSDSGSENSKFEVKKFSFLPKMVFE 240

Query: 969  KHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 1148
            +HEE++YLR+V++I+S+GV KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGVVE
Sbjct: 241  RHEEFLYLRLVQDIISDGVLKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGVVE 300

Query: 1149 ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1328
            ELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGARY
Sbjct: 301  ELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQWRHFGARY 360

Query: 1329 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1508
            TDMHADYTGQGFDQLLDV+ KIK+NPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA G
Sbjct: 361  TDMHADYTGQGFDQLLDVIDKIKSNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANG 420

Query: 1509 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1688
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVC+LVPGDFIH  GDAHVY +HVRPLQ
Sbjct: 421  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCNLVPGDFIHVFGDAHVYSSHVRPLQ 480

Query: 1689 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            EQLQKLPKPFPIL IN EK++IDSFVAADF
Sbjct: 481  EQLQKLPKPFPILMINPEKKNIDSFVAADF 510


>gb|OMO75612.1| Thymidylate synthase [Corchorus olitorius]
          Length = 529

 Score =  887 bits (2291), Expect = 0.0
 Identities = 425/512 (83%), Positives = 469/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITM 428
            M+ D +M+I NG+G  +   DPQRT+Q+VVAAT+++GIGKDGK+PW+LPSDLKFFKD+T+
Sbjct: 1    MSADIMMNISNGNGNGNAQPDPQRTFQIVVAATKDLGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 429  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSAL 608
            TTSD  KKNAVIMGRKTWESIPL+HRPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQHRPLPGRLNVVLTRSGSFDIATAENVVICGSMASAL 120

Query: 609  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 788
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE RIECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETRIECDTFMPAIDSSVFQ 180

Query: 789  PWYSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 962
            PWYSS P+VENNIRYCFTTYVRVR+SAVE   Q N    D+   + KFEIQKFSFLPK I
Sbjct: 181  PWYSSFPVVENNIRYCFTTYVRVRNSAVENLSQNNDKILDSIPATSKFEIQKFSFLPKMI 240

Query: 963  FEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 1142
            FEKHEEY+YL+MV++I+++G  KDDRT TGT+S FGCQMRFNLR++FPLLTTKKVFWRGV
Sbjct: 241  FEKHEEYLYLKMVQDIIADGNLKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGV 300

Query: 1143 VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1322
            VEELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1323 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1502
            RYTDMHADYTGQGFDQLLDV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1503 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1682
             GELSCQ YQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+H +GD HVY  HVRP
Sbjct: 421  NGELSCQTYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHVLGDTHVYSNHVRP 480

Query: 1683 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            LQEQLQKLPKPFPILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFPILKINPEKKNIDSFVASDF 512


>gb|OMO74316.1| Thymidylate synthase [Corchorus capsularis]
          Length = 529

 Score =  886 bits (2290), Expect = 0.0
 Identities = 424/512 (82%), Positives = 469/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITM 428
            M+ D +M+IPNG+G  +   DPQRT+Q+VVAAT+++GIGKDGK+PW+LPSDLKFFKD+T+
Sbjct: 1    MSADIMMNIPNGNGNGNAQPDPQRTFQIVVAATKDLGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 429  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSAL 608
            TTSD  KKNAVIMGRKTWESIPL+HRPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQHRPLPGRLNVVLTRSGSFDIATAENVVICGSMASAL 120

Query: 609  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 788
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE  IECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETNIECDTFMPAIDSSVFQ 180

Query: 789  PWYSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 962
            PWYSS P+VENNIRYCFTTYVRVR+SAVE   Q      D+   + KFEIQKFSFLPK I
Sbjct: 181  PWYSSFPVVENNIRYCFTTYVRVRNSAVENLSQNKDKILDSIPATSKFEIQKFSFLPKMI 240

Query: 963  FEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 1142
            FEKHEEY+YL+MV++I+++G  KDDRT TGT+S FGCQMRFNLR++FPLLTTKKVFWRGV
Sbjct: 241  FEKHEEYLYLKMVQDIIADGNLKDDRTGTGTLSKFGCQMRFNLRRTFPLLTTKKVFWRGV 300

Query: 1143 VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1322
            VEELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1323 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1502
            RYTDMHADYTG+GFDQLLDV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGKGFDQLLDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1503 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1682
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDF+H +GD HVY  HVRP
Sbjct: 421  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFVHVLGDTHVYSNHVRP 480

Query: 1683 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            LQEQLQKLPKPFPILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFPILKINPEKKNIDSFVASDF 512


>ref|XP_021285499.1| bifunctional dihydrofolate reductase-thymidylate synthase-like
            isoform X1 [Herrania umbratica]
          Length = 529

 Score =  886 bits (2289), Expect = 0.0
 Identities = 425/512 (83%), Positives = 470/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITM 428
            M+ D +MSIPNG+G  +   DPQRTYQVVVAAT+++GIGKDGK+PW+LPSDLKFFKD+T+
Sbjct: 1    MSADIMMSIPNGNGNGNAQPDPQRTYQVVVAATKDLGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 429  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSAL 608
            TTSD  KKNAVIMGRKTWESIPL++RPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQNRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSAL 120

Query: 609  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 788
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE  IECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETSIECDTFMPSIDSSVFQ 180

Query: 789  PWYSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 962
            PW+SS P+VENNIRYCFTT+VRVR+SAVE   Q +    D   D+GKFE++KFSFLPK I
Sbjct: 181  PWHSSFPVVENNIRYCFTTFVRVRNSAVEHISQNSDQVFDDKPDAGKFEVKKFSFLPKMI 240

Query: 963  FEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 1142
            FEKHEEY+YL+MV++I+S+G  KDDRT TGT S FGCQMRFNLRK+FPLLTTKKVFWRGV
Sbjct: 241  FEKHEEYLYLKMVQDIISDGNLKDDRTGTGTFSKFGCQMRFNLRKTFPLLTTKKVFWRGV 300

Query: 1143 VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1322
            VEELLWFISGSTNAKVLQ+ GIHIW+GN SRD+LDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQDMGIHIWDGNASRDFLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1323 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1502
            RYTDMHADYTGQGFDQLLDV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1503 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1682
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDL+PGDFIH +GDAHVY  HVRP
Sbjct: 421  YGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVLGDAHVYSNHVRP 480

Query: 1683 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            LQEQLQKLPKPFPILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFPILKINPEKKNIDSFVASDF 512


>ref|XP_007042127.2| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            [Theobroma cacao]
          Length = 529

 Score =  886 bits (2289), Expect = 0.0
 Identities = 426/512 (83%), Positives = 470/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITM 428
            M+ D +MSIPNG+G  +   DPQRTYQVVVAAT++MGIGKDGK+PW+LPSDLKFFKD+T+
Sbjct: 1    MSADIMMSIPNGNGNGNAQPDPQRTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 429  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSAL 608
            TTSD  KKNAVIMGRKTWESIPL++RPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQNRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSAL 120

Query: 609  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 788
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE  IECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETSIECDTFMPSIDSSVFQ 180

Query: 789  PWYSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 962
            PWYSS P+VEN+IRYCFTT+VRVR+SAVE   Q +    D   D+GKFE++KFSFLPK I
Sbjct: 181  PWYSSFPVVENDIRYCFTTFVRVRNSAVEHISQNSDQVFDDKPDAGKFEVKKFSFLPKMI 240

Query: 963  FEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 1142
            FEKHEEY+YL+MV++I+S+G  KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGV
Sbjct: 241  FEKHEEYLYLKMVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGV 300

Query: 1143 VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1322
            VEELLWFISGSTNAKVLQ+KGIHIW+GN SRD+LDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQDKGIHIWDGNASRDFLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1323 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1502
            RYTDMHADYTGQGFDQL DV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGQGFDQLSDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1503 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1682
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIH +GDAHVY  HVRP
Sbjct: 421  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHVLGDAHVYTNHVRP 480

Query: 1683 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            LQEQLQKLPKPF ILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFSILKINPEKKNIDSFVASDF 512


>ref|XP_011037491.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like [Populus euphratica]
 ref|XP_011037492.1| PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase
            1-like [Populus euphratica]
          Length = 528

 Score =  884 bits (2285), Expect = 0.0
 Identities = 423/511 (82%), Positives = 470/511 (91%), Gaps = 3/511 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHTD-PQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITMT 431
            M+GD++ ++ NG+  T    PQ+TYQVVVAAT++MGIGKDGK+PW+LPSDLKFFKD+T+T
Sbjct: 1    MSGDSVANLSNGNANTQQPAPQKTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDLTLT 60

Query: 432  TSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSALE 611
            T D  KKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVVICGSM SALE
Sbjct: 61   TMDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALE 120

Query: 612  LLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQP 791
            LLAASPYC+SIEKVFVIGGGQI RE+LNAPGCDAIHIT+IE   +CDTFIP +D SVFQP
Sbjct: 121  LLAASPYCLSIEKVFVIGGGQILRESLNAPGCDAIHITEIEMDFDCDTFIPAIDTSVFQP 180

Query: 792  WYSSVPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIF 965
            WYSS P VEN+IR+CFTTYVRVRSS +E   Q NG +SD NS++ KFE+ KFSFLPK +F
Sbjct: 181  WYSSFPNVENDIRHCFTTYVRVRSSTIESHSQNNGENSDGNSENSKFEVMKFSFLPKMVF 240

Query: 966  EKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVV 1145
            E+HEEY+YLRMV++I+S+G  KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGVV
Sbjct: 241  ERHEEYLYLRMVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKNFPLLTTKKVFWRGVV 300

Query: 1146 EELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGAR 1325
            EELLWFISGST+AKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGP+YGFQWRHFGAR
Sbjct: 301  EELLWFISGSTSAKVLQEKGIHIWDGNASRDYLDSIGLKDREEGDLGPVYGFQWRHFGAR 360

Query: 1326 YTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAK 1505
            YTDMHADYTGQGFDQLLDV+ KIKNNP+DRRII+SAWNPSDLKLMALPPCHMFAQFYVA 
Sbjct: 361  YTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIIISAWNPSDLKLMALPPCHMFAQFYVAN 420

Query: 1506 GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPL 1685
            GELSCQMYQRSADMGLGVPFNIASYALLTC+IAHVCDL+PGDF+H IGDAHVY TH+RPL
Sbjct: 421  GELSCQMYQRSADMGLGVPFNIASYALLTCIIAHVCDLIPGDFVHVIGDAHVYHTHIRPL 480

Query: 1686 QEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            QEQL+KLPKPFPILKINSEK+DID+FVAADF
Sbjct: 481  QEQLRKLPKPFPILKINSEKKDIDTFVAADF 511


>ref|XP_010254750.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X2 [Nelumbo nucifera]
          Length = 569

 Score =  884 bits (2285), Expect = 0.0
 Identities = 427/512 (83%), Positives = 462/512 (90%), Gaps = 2/512 (0%)
 Frame = +3

Query: 249  SLMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITM 428
            S+MAG+T+M++PNG+     DP+RT+QVVVAAT++MGIGKDGK+PWRLPSDLKFF+++TM
Sbjct: 41   SVMAGETIMNVPNGNASIQPDPKRTFQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTM 100

Query: 429  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSAL 608
             TSDP KKNAVIMGRKTWE IP EHRPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 101  GTSDPAKKNAVIMGRKTWEGIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSAL 160

Query: 609  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 788
            ELLA+SPYC+SIEKVFVIGGGQI RE+LNAP CDAIHIT+IE   ECDTFIPP++ SVFQ
Sbjct: 161  ELLASSPYCLSIEKVFVIGGGQILRESLNAPECDAIHITEIETSFECDTFIPPIELSVFQ 220

Query: 789  PWYSSVPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKI 962
            PWYSS PL+ENNIR  F TYVRVR SA E   Q NG   D NS++ KFEI+KFSFLPK I
Sbjct: 221  PWYSSFPLIENNIRCSFVTYVRVRRSAAEYLYQDNGGMFDGNSNNTKFEIEKFSFLPKMI 280

Query: 963  FEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 1142
            FE+HEEYMYLR+VE+I+SNG  KDDRT TGT+S FGCQM FNLRKSFPLLTTKKVFWRGV
Sbjct: 281  FERHEEYMYLRLVEDIISNGNQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFWRGV 340

Query: 1143 VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1322
            VEELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGPIYGFQWRH GA
Sbjct: 341  VEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRHHGA 400

Query: 1323 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1502
            RYT+MHADY+GQGFDQLLDV+ KIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYV 
Sbjct: 401  RYTNMHADYSGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVV 460

Query: 1503 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1682
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDL+PGDFIH IGDAHVY THVRP
Sbjct: 461  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTHVRP 520

Query: 1683 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            LQEQLQKLPKPFPILKIN  K+DIDSFVA DF
Sbjct: 521  LQEQLQKLPKPFPILKINPHKKDIDSFVATDF 552


>ref|XP_010254749.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X1 [Nelumbo nucifera]
          Length = 578

 Score =  884 bits (2285), Expect = 0.0
 Identities = 427/512 (83%), Positives = 462/512 (90%), Gaps = 2/512 (0%)
 Frame = +3

Query: 249  SLMAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITM 428
            S+MAG+T+M++PNG+     DP+RT+QVVVAAT++MGIGKDGK+PWRLPSDLKFF+++TM
Sbjct: 50   SVMAGETIMNVPNGNASIQPDPKRTFQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTM 109

Query: 429  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSAL 608
             TSDP KKNAVIMGRKTWE IP EHRPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 110  GTSDPAKKNAVIMGRKTWEGIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSAL 169

Query: 609  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 788
            ELLA+SPYC+SIEKVFVIGGGQI RE+LNAP CDAIHIT+IE   ECDTFIPP++ SVFQ
Sbjct: 170  ELLASSPYCLSIEKVFVIGGGQILRESLNAPECDAIHITEIETSFECDTFIPPIELSVFQ 229

Query: 789  PWYSSVPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKI 962
            PWYSS PL+ENNIR  F TYVRVR SA E   Q NG   D NS++ KFEI+KFSFLPK I
Sbjct: 230  PWYSSFPLIENNIRCSFVTYVRVRRSAAEYLYQDNGGMFDGNSNNTKFEIEKFSFLPKMI 289

Query: 963  FEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 1142
            FE+HEEYMYLR+VE+I+SNG  KDDRT TGT+S FGCQM FNLRKSFPLLTTKKVFWRGV
Sbjct: 290  FERHEEYMYLRLVEDIISNGNQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFWRGV 349

Query: 1143 VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1322
            VEELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGPIYGFQWRH GA
Sbjct: 350  VEELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRHHGA 409

Query: 1323 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1502
            RYT+MHADY+GQGFDQLLDV+ KIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYV 
Sbjct: 410  RYTNMHADYSGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVV 469

Query: 1503 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1682
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDL+PGDFIH IGDAHVY THVRP
Sbjct: 470  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTHVRP 529

Query: 1683 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            LQEQLQKLPKPFPILKIN  K+DIDSFVA DF
Sbjct: 530  LQEQLQKLPKPFPILKINPHKKDIDSFVATDF 561


>gb|EOX97956.1| Thymidylate synthase 1 isoform 1 [Theobroma cacao]
 gb|EOX97958.1| Thymidylate synthase 1 isoform 1 [Theobroma cacao]
          Length = 529

 Score =  884 bits (2285), Expect = 0.0
 Identities = 425/512 (83%), Positives = 470/512 (91%), Gaps = 4/512 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHT--DPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITM 428
            M+ D +MSIPNG+G  +   DPQRTYQVVVAAT++MGIGKDGK+PW+LPSDLKFFKD+T+
Sbjct: 1    MSADIMMSIPNGNGNGNAQPDPQRTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDVTL 60

Query: 429  TTSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSAL 608
            TTSD  KKNAVIMGRKTWESIPL++RPLP RLNVVLTRSGSFDIATAENVVICGSM SAL
Sbjct: 61   TTSDSGKKNAVIMGRKTWESIPLQNRPLPGRLNVVLTRSGSFDIATAENVVICGSMTSAL 120

Query: 609  ELLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQ 788
            ELLAASPYC+SIEKVFVIGGGQI+RE+LNAPGCDAIHIT+IE  IECDTF+P +D SVFQ
Sbjct: 121  ELLAASPYCLSIEKVFVIGGGQIFRESLNAPGCDAIHITEIETSIECDTFMPSIDSSVFQ 180

Query: 789  PWYSSVPLVENNIRYCFTTYVRVRSSAVE--PQTNGLSSDTNSDSGKFEIQKFSFLPKKI 962
            PWYSS P+VEN+IRYCFTT+VRVR+SAVE   Q +    D   D+GKFE++KFSFLPK I
Sbjct: 181  PWYSSFPVVENDIRYCFTTFVRVRNSAVEHISQNSDQVFDDKPDAGKFEVKKFSFLPKMI 240

Query: 963  FEKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGV 1142
            F+KHEEY+YL+MV++I+S+G  KDDRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGV
Sbjct: 241  FKKHEEYLYLKMVQDIISDGNLKDDRTGTGTLSKFGCQMRFNLRKTFPLLTTKKVFWRGV 300

Query: 1143 VEELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGA 1322
            VEELLWFISGSTNAKVLQ+KGIHIW+GN SRD+LDSIGL DREEGDLGP+YGFQWRHFGA
Sbjct: 301  VEELLWFISGSTNAKVLQDKGIHIWDGNASRDFLDSIGLTDREEGDLGPVYGFQWRHFGA 360

Query: 1323 RYTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 1502
            RYTDMHADYTGQGFDQL DV+ KIKNNP+DRRIILSAWNPSDLKLMALPPCHMFAQFYVA
Sbjct: 361  RYTDMHADYTGQGFDQLSDVIDKIKNNPNDRRIILSAWNPSDLKLMALPPCHMFAQFYVA 420

Query: 1503 KGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRP 1682
             GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIH +GDAHVY  HVRP
Sbjct: 421  NGELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHVLGDAHVYTNHVRP 480

Query: 1683 LQEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            LQEQLQKLPKPF ILKIN EK++IDSFVA+DF
Sbjct: 481  LQEQLQKLPKPFSILKINPEKKNIDSFVASDF 512


>ref|XP_006384511.1| hypothetical protein POPTR_0004s16470g [Populus trichocarpa]
 ref|XP_002306118.2| hypothetical protein POPTR_0004s16470g [Populus trichocarpa]
 ref|XP_006384512.1| dihydrofolate reductase-thymidylate synthase family protein [Populus
            trichocarpa]
          Length = 528

 Score =  883 bits (2281), Expect = 0.0
 Identities = 421/511 (82%), Positives = 472/511 (92%), Gaps = 3/511 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITH-TDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITMT 431
            M+GD++ ++ NG+  T  +DP++TYQVVVAAT++MGIGKDGK+PW+LPSDLKFFKD+T+T
Sbjct: 1    MSGDSVANLSNGNANTQQSDPRKTYQVVVAATKDMGIGKDGKLPWKLPSDLKFFKDLTLT 60

Query: 432  TSDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSALE 611
            T D  KKNAVIMGRKTWESIPLEHRPLP RLNVVLTRSGSFDIATAENVVICGSM SALE
Sbjct: 61   TMDSGKKNAVIMGRKTWESIPLEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMGSALE 120

Query: 612  LLAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQP 791
            LLAASPYC+SIEKVFVIGGGQI RE+LNAPGCDAIHIT+IE   +CDTFIP +D SVFQP
Sbjct: 121  LLAASPYCLSIEKVFVIGGGQILRESLNAPGCDAIHITEIETDFDCDTFIPAIDTSVFQP 180

Query: 792  WYSSVPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIF 965
            WYSS P VEN+IR+CFTTYVRVRSS +E   Q NG +SD NS++ KFE++KFSFLPK +F
Sbjct: 181  WYSSFPKVENDIRHCFTTYVRVRSSTIESHSQNNGENSDGNSENSKFEVKKFSFLPKMVF 240

Query: 966  EKHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVV 1145
            E+HEEY+YLRMV++I+S+G  K DRT TGT+S FGCQMRFNLRK+FPLLTTKKVFWRGVV
Sbjct: 241  ERHEEYLYLRMVQDIISDGNLKGDRTGTGTLSKFGCQMRFNLRKNFPLLTTKKVFWRGVV 300

Query: 1146 EELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGAR 1325
            EELLWFISGST+AKVLQEKGIHIW+GN SR+YLDSIGL DREEGDLGP+YGFQWRHFGAR
Sbjct: 301  EELLWFISGSTSAKVLQEKGIHIWDGNASREYLDSIGLKDREEGDLGPVYGFQWRHFGAR 360

Query: 1326 YTDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAK 1505
            YTDMHADYTGQGFDQLLDV+ KIKNNP+DRRII+SAWNPSDLKLMALPPCHMFAQFYVA 
Sbjct: 361  YTDMHADYTGQGFDQLLDVIDKIKNNPNDRRIIISAWNPSDLKLMALPPCHMFAQFYVAN 420

Query: 1506 GELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPL 1685
            GELSCQMYQRSADMGLGVPFNIASYALLTC+IAHVCDL+PGDF+H IGDAHVY TH+RPL
Sbjct: 421  GELSCQMYQRSADMGLGVPFNIASYALLTCIIAHVCDLIPGDFVHVIGDAHVYHTHIRPL 480

Query: 1686 QEQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            QEQL+KLPKPFPILKINSEK+DID+FVAADF
Sbjct: 481  QEQLRKLPKPFPILKINSEKKDIDTFVAADF 511


>ref|XP_010254751.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X3 [Nelumbo nucifera]
 ref|XP_010254752.1| PREDICTED: putative bifunctional dihydrofolate reductase-thymidylate
            synthase isoform X3 [Nelumbo nucifera]
          Length = 527

 Score =  882 bits (2280), Expect = 0.0
 Identities = 426/510 (83%), Positives = 460/510 (90%), Gaps = 2/510 (0%)
 Frame = +3

Query: 255  MAGDTLMSIPNGSGITHTDPQRTYQVVVAATQNMGIGKDGKMPWRLPSDLKFFKDITMTT 434
            MAG+T+M++PNG+     DP+RT+QVVVAAT++MGIGKDGK+PWRLPSDLKFF+++TM T
Sbjct: 1    MAGETIMNVPNGNASIQPDPKRTFQVVVAATKSMGIGKDGKLPWRLPSDLKFFREVTMGT 60

Query: 435  SDPVKKNAVIMGRKTWESIPLEHRPLPNRLNVVLTRSGSFDIATAENVVICGSMVSALEL 614
            SDP KKNAVIMGRKTWE IP EHRPLP RLNVVLTRSGSFDIATAENVVICGSM SALEL
Sbjct: 61   SDPAKKNAVIMGRKTWEGIPPEHRPLPGRLNVVLTRSGSFDIATAENVVICGSMSSALEL 120

Query: 615  LAASPYCVSIEKVFVIGGGQIYREALNAPGCDAIHITQIEERIECDTFIPPLDESVFQPW 794
            LA+SPYC+SIEKVFVIGGGQI RE+LNAP CDAIHIT+IE   ECDTFIPP++ SVFQPW
Sbjct: 121  LASSPYCLSIEKVFVIGGGQILRESLNAPECDAIHITEIETSFECDTFIPPIELSVFQPW 180

Query: 795  YSSVPLVENNIRYCFTTYVRVRSSAVEP--QTNGLSSDTNSDSGKFEIQKFSFLPKKIFE 968
            YSS PL+ENNIR  F TYVRVR SA E   Q NG   D NS++ KFEI+KFSFLPK IFE
Sbjct: 181  YSSFPLIENNIRCSFVTYVRVRRSAAEYLYQDNGGMFDGNSNNTKFEIEKFSFLPKMIFE 240

Query: 969  KHEEYMYLRMVENILSNGVSKDDRTRTGTISIFGCQMRFNLRKSFPLLTTKKVFWRGVVE 1148
            +HEEYMYLR+VE+I+SNG  KDDRT TGT+S FGCQM FNLRKSFPLLTTKKVFWRGVVE
Sbjct: 241  RHEEYMYLRLVEDIISNGNQKDDRTGTGTLSKFGCQMHFNLRKSFPLLTTKKVFWRGVVE 300

Query: 1149 ELLWFISGSTNAKVLQEKGIHIWEGNGSRDYLDSIGLVDREEGDLGPIYGFQWRHFGARY 1328
            ELLWFISGSTNAKVLQEKGIHIW+GN SRDYLDSIGL DREEGDLGPIYGFQWRH GARY
Sbjct: 301  ELLWFISGSTNAKVLQEKGIHIWDGNASRDYLDSIGLTDREEGDLGPIYGFQWRHHGARY 360

Query: 1329 TDMHADYTGQGFDQLLDVVSKIKNNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVAKG 1508
            T+MHADY+GQGFDQLLDV+ KIKN PDDRRIILSAWNPSDLKLMALPPCHMFAQFYV  G
Sbjct: 361  TNMHADYSGQGFDQLLDVIDKIKNKPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVVNG 420

Query: 1509 ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHTIGDAHVYCTHVRPLQ 1688
            ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDL+PGDFIH IGDAHVY THVRPLQ
Sbjct: 421  ELSCQMYQRSADMGLGVPFNIASYALLTCMIAHVCDLIPGDFIHVIGDAHVYRTHVRPLQ 480

Query: 1689 EQLQKLPKPFPILKINSEKRDIDSFVAADF 1778
            EQLQKLPKPFPILKIN  K+DIDSFVA DF
Sbjct: 481  EQLQKLPKPFPILKINPHKKDIDSFVATDF 510