BLASTX nr result
ID: Wisteria21_contig00018769
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Wisteria21_contig00018769
(316 letters)
Database: ./nr
77,306,371 sequences; 28,104,191,420 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|KHN11180.1| G-type lectin S-receptor-like serine/threonine-pr... 197 2e-48
gb|KHN11179.1| G-type lectin S-receptor-like serine/threonine-pr... 197 2e-48
ref|XP_006582205.1| PREDICTED: G-type lectin S-receptor-like ser... 197 2e-48
ref|XP_006582204.1| PREDICTED: G-type lectin S-receptor-like ser... 197 2e-48
gb|KHN00064.1| G-type lectin S-receptor-like serine/threonine-pr... 196 4e-48
gb|KRH25971.1| hypothetical protein GLYMA_12G142800 [Glycine max] 196 6e-48
gb|KHN37219.1| G-type lectin S-receptor-like serine/threonine-pr... 196 6e-48
ref|XP_003541083.1| PREDICTED: G-type lectin S-receptor-like ser... 196 6e-48
gb|KRH55466.1| hypothetical protein GLYMA_06G257000 [Glycine max] 194 2e-47
ref|XP_006582198.1| PREDICTED: G-type lectin S-receptor-like ser... 194 2e-47
ref|XP_003526125.2| PREDICTED: G-type lectin S-receptor-like ser... 194 2e-47
gb|KRH55459.1| hypothetical protein GLYMA_06G256400 [Glycine max] 193 4e-47
gb|KRH55458.1| hypothetical protein GLYMA_06G256400 [Glycine max] 193 4e-47
gb|KOM49384.1| hypothetical protein LR48_Vigan08g021100 [Vigna a... 193 4e-47
gb|KHN00060.1| G-type lectin S-receptor-like serine/threonine-pr... 193 4e-47
ref|XP_006582203.1| PREDICTED: G-type lectin S-receptor-like ser... 193 4e-47
gb|KRH25979.1| hypothetical protein GLYMA_12G143200 [Glycine max] 193 5e-47
gb|KHN37216.1| G-type lectin S-receptor-like serine/threonine-pr... 193 5e-47
ref|XP_006592566.1| PREDICTED: G-type lectin S-receptor-like ser... 193 5e-47
ref|XP_003541085.2| PREDICTED: G-type lectin S-receptor-like ser... 193 5e-47
>gb|KHN11180.1| G-type lectin S-receptor-like serine/threonine-protein kinase
[Glycine soja]
Length = 795
Score = 197 bits (502), Expect = 2e-48
Identities = 96/105 (91%), Positives = 100/105 (95%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN+SLDYFVFDETKR LDW KRFN
Sbjct: 519 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNQSLDYFVFDETKRKMLDWHKRFN 578
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
IISGIARGLLYLHQDSRLRIIHRDLK SNILLD NLDPKISDFGL
Sbjct: 579 IISGIARGLLYLHQDSRLRIIHRDLKPSNILLDANLDPKISDFGL 623
>gb|KHN11179.1| G-type lectin S-receptor-like serine/threonine-protein kinase
[Glycine soja]
Length = 816
Score = 197 bits (502), Expect = 2e-48
Identities = 95/105 (90%), Positives = 100/105 (95%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN+SLDYF+FDETKR LDW KRFN
Sbjct: 540 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNQSLDYFIFDETKRKLLDWHKRFN 599
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
IISGIARGLLYLHQDSRLRIIHRDLKTSNILLD N DPKISDFGL
Sbjct: 600 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDANFDPKISDFGL 644
>ref|XP_006582205.1| PREDICTED: G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290-like isoform X2 [Glycine max]
gi|947107089|gb|KRH55472.1| hypothetical protein
GLYMA_06G257500 [Glycine max]
Length = 780
Score = 197 bits (502), Expect = 2e-48
Identities = 95/105 (90%), Positives = 100/105 (95%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN+SLDYF+FDETKR LDW KRFN
Sbjct: 504 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNQSLDYFIFDETKRKLLDWHKRFN 563
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
IISGIARGLLYLHQDSRLRIIHRDLKTSNILLD N DPKISDFGL
Sbjct: 564 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDANFDPKISDFGL 608
>ref|XP_006582204.1| PREDICTED: G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290-like isoform X1 [Glycine max]
gi|947107088|gb|KRH55471.1| hypothetical protein
GLYMA_06G257500 [Glycine max]
Length = 816
Score = 197 bits (502), Expect = 2e-48
Identities = 95/105 (90%), Positives = 100/105 (95%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN+SLDYF+FDETKR LDW KRFN
Sbjct: 540 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNQSLDYFIFDETKRKLLDWHKRFN 599
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
IISGIARGLLYLHQDSRLRIIHRDLKTSNILLD N DPKISDFGL
Sbjct: 600 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDANFDPKISDFGL 644
>gb|KHN00064.1| G-type lectin S-receptor-like serine/threonine-protein kinase
[Glycine soja]
Length = 783
Score = 196 bits (499), Expect = 4e-48
Identities = 96/105 (91%), Positives = 100/105 (95%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN+SLDYFVFDETKR LDW KRFN
Sbjct: 507 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNQSLDYFVFDETKRKFLDWGKRFN 566
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
II GIARGLLYLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 567 IIIGIARGLLYLHQDSRLRIIHRDLKTSNILLDENLDPKISDFGL 611
>gb|KRH25971.1| hypothetical protein GLYMA_12G142800 [Glycine max]
Length = 808
Score = 196 bits (498), Expect = 6e-48
Identities = 94/105 (89%), Positives = 100/105 (95%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LI+KLQHRNLVKLLGCCI+GEEKML+YEYMPN SLDYFVFDETKR LDW KRFN
Sbjct: 536 KNEVTLISKLQHRNLVKLLGCCIEGEEKMLIYEYMPNHSLDYFVFDETKRKLLDWHKRFN 595
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
+I+GIARGLLYLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 596 VITGIARGLLYLHQDSRLRIIHRDLKTSNILLDANLDPKISDFGL 640
>gb|KHN37219.1| G-type lectin S-receptor-like serine/threonine-protein kinase SD1-1
[Glycine soja]
Length = 677
Score = 196 bits (498), Expect = 6e-48
Identities = 94/105 (89%), Positives = 100/105 (95%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LI+KLQHRNLVKLLGCCI+GEEKML+YEYMPN SLDYFVFDETKR LDW KRFN
Sbjct: 405 KNEVTLISKLQHRNLVKLLGCCIEGEEKMLIYEYMPNHSLDYFVFDETKRKLLDWHKRFN 464
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
+I+GIARGLLYLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 465 VITGIARGLLYLHQDSRLRIIHRDLKTSNILLDANLDPKISDFGL 509
>ref|XP_003541083.1| PREDICTED: G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290-like [Glycine max]
Length = 814
Score = 196 bits (498), Expect = 6e-48
Identities = 94/105 (89%), Positives = 100/105 (95%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LI+KLQHRNLVKLLGCCI+GEEKML+YEYMPN SLDYFVFDETKR LDW KRFN
Sbjct: 542 KNEVTLISKLQHRNLVKLLGCCIEGEEKMLIYEYMPNHSLDYFVFDETKRKLLDWHKRFN 601
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
+I+GIARGLLYLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 602 VITGIARGLLYLHQDSRLRIIHRDLKTSNILLDANLDPKISDFGL 646
>gb|KRH55466.1| hypothetical protein GLYMA_06G257000 [Glycine max]
Length = 812
Score = 194 bits (493), Expect = 2e-47
Identities = 95/105 (90%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN+SLDYFVFDETKR LDW KR N
Sbjct: 536 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNQSLDYFVFDETKRKFLDWGKRLN 595
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
II GIARGLLYLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 596 IIIGIARGLLYLHQDSRLRIIHRDLKTSNILLDENLDPKISDFGL 640
>ref|XP_006582198.1| PREDICTED: G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290-like isoform X2 [Glycine max]
Length = 777
Score = 194 bits (493), Expect = 2e-47
Identities = 95/105 (90%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN+SLDYFVFDETKR LDW KR N
Sbjct: 501 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNQSLDYFVFDETKRKFLDWGKRLN 560
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
II GIARGLLYLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 561 IIIGIARGLLYLHQDSRLRIIHRDLKTSNILLDENLDPKISDFGL 605
>ref|XP_003526125.2| PREDICTED: G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290-like isoform X1 [Glycine max]
Length = 814
Score = 194 bits (493), Expect = 2e-47
Identities = 95/105 (90%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN+SLDYFVFDETKR LDW KR N
Sbjct: 538 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNQSLDYFVFDETKRKFLDWGKRLN 597
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
II GIARGLLYLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 598 IIIGIARGLLYLHQDSRLRIIHRDLKTSNILLDENLDPKISDFGL 642
>gb|KRH55459.1| hypothetical protein GLYMA_06G256400 [Glycine max]
Length = 662
Score = 193 bits (491), Expect = 4e-47
Identities = 92/105 (87%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LI+KLQHRNLVKLLGCCI G+EKML+YE+MPN SLDYFVFDETKR LDWPKRFN
Sbjct: 539 KNEVALISKLQHRNLVKLLGCCIDGDEKMLIYEFMPNHSLDYFVFDETKRKFLDWPKRFN 598
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
II+GIARGLLYLHQDSRLRIIHRDLKTSN+LLD NL PKISDFGL
Sbjct: 599 IINGIARGLLYLHQDSRLRIIHRDLKTSNVLLDANLHPKISDFGL 643
>gb|KRH55458.1| hypothetical protein GLYMA_06G256400 [Glycine max]
Length = 773
Score = 193 bits (491), Expect = 4e-47
Identities = 92/105 (87%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LI+KLQHRNLVKLLGCCI G+EKML+YE+MPN SLDYFVFDETKR LDWPKRFN
Sbjct: 497 KNEVALISKLQHRNLVKLLGCCIDGDEKMLIYEFMPNHSLDYFVFDETKRKFLDWPKRFN 556
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
II+GIARGLLYLHQDSRLRIIHRDLKTSN+LLD NL PKISDFGL
Sbjct: 557 IINGIARGLLYLHQDSRLRIIHRDLKTSNVLLDANLHPKISDFGL 601
>gb|KOM49384.1| hypothetical protein LR48_Vigan08g021100 [Vigna angularis]
Length = 802
Score = 193 bits (491), Expect = 4e-47
Identities = 93/105 (88%), Positives = 100/105 (95%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPNKSLD+FVFDETKR +DW RFN
Sbjct: 526 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNKSLDFFVFDETKRKLVDWRMRFN 585
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
IISGIARGLLYLHQDSRLRIIHRDLKTSNILLD N+DPKI+DFGL
Sbjct: 586 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDTNMDPKIADFGL 630
>gb|KHN00060.1| G-type lectin S-receptor-like serine/threonine-protein kinase
[Glycine soja]
Length = 804
Score = 193 bits (491), Expect = 4e-47
Identities = 92/105 (87%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LI+KLQHRNLVKLLGCCI G+EKML+YE+MPN SLDYFVFDETKR LDWPKRFN
Sbjct: 528 KNEVALISKLQHRNLVKLLGCCIDGDEKMLIYEFMPNHSLDYFVFDETKRKFLDWPKRFN 587
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
II+GIARGLLYLHQDSRLRIIHRDLKTSN+LLD NL PKISDFGL
Sbjct: 588 IINGIARGLLYLHQDSRLRIIHRDLKTSNVLLDANLHPKISDFGL 632
>ref|XP_006582203.1| PREDICTED: G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290-like [Glycine max]
gi|947107074|gb|KRH55457.1| hypothetical protein
GLYMA_06G256400 [Glycine max]
Length = 815
Score = 193 bits (491), Expect = 4e-47
Identities = 92/105 (87%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LI+KLQHRNLVKLLGCCI G+EKML+YE+MPN SLDYFVFDETKR LDWPKRFN
Sbjct: 539 KNEVALISKLQHRNLVKLLGCCIDGDEKMLIYEFMPNHSLDYFVFDETKRKFLDWPKRFN 598
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
II+GIARGLLYLHQDSRLRIIHRDLKTSN+LLD NL PKISDFGL
Sbjct: 599 IINGIARGLLYLHQDSRLRIIHRDLKTSNVLLDANLHPKISDFGL 643
>gb|KRH25979.1| hypothetical protein GLYMA_12G143200 [Glycine max]
Length = 839
Score = 193 bits (490), Expect = 5e-47
Identities = 93/105 (88%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN SLD F+FDETK+ LDWPKRFN
Sbjct: 563 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNLSLDCFLFDETKKKLLDWPKRFN 622
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
IISGI RGL+YLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 623 IISGITRGLVYLHQDSRLRIIHRDLKTSNILLDDNLDPKISDFGL 667
>gb|KHN37216.1| G-type lectin S-receptor-like serine/threonine-protein kinase
[Glycine soja]
Length = 809
Score = 193 bits (490), Expect = 5e-47
Identities = 93/105 (88%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN SLD F+FDETK+ LDWPKRFN
Sbjct: 533 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNLSLDCFLFDETKKKLLDWPKRFN 592
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
IISGI RGL+YLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 593 IISGITRGLVYLHQDSRLRIIHRDLKTSNILLDDNLDPKISDFGL 637
>ref|XP_006592566.1| PREDICTED: G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290-like isoform X2 [Glycine max]
Length = 800
Score = 193 bits (490), Expect = 5e-47
Identities = 93/105 (88%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN SLD F+FDETK+ LDWPKRFN
Sbjct: 524 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNLSLDCFLFDETKKKLLDWPKRFN 583
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
IISGI RGL+YLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 584 IISGITRGLVYLHQDSRLRIIHRDLKTSNILLDDNLDPKISDFGL 628
>ref|XP_003541085.2| PREDICTED: G-type lectin S-receptor-like serine/threonine-protein
kinase At4g27290-like isoform X1 [Glycine max]
gi|947077138|gb|KRH25978.1| hypothetical protein
GLYMA_12G143200 [Glycine max]
Length = 835
Score = 193 bits (490), Expect = 5e-47
Identities = 93/105 (88%), Positives = 99/105 (94%)
Frame = -1
Query: 316 KNEVSLIAKLQHRNLVKLLGCCIQGEEKMLVYEYMPNKSLDYFVFDETKRISLDWPKRFN 137
KNEV+LIAKLQHRNLVKLLGCCI+GEEKML+YEYMPN SLD F+FDETK+ LDWPKRFN
Sbjct: 559 KNEVALIAKLQHRNLVKLLGCCIEGEEKMLIYEYMPNLSLDCFLFDETKKKLLDWPKRFN 618
Query: 136 IISGIARGLLYLHQDSRLRIIHRDLKTSNILLDGNLDPKISDFGL 2
IISGI RGL+YLHQDSRLRIIHRDLKTSNILLD NLDPKISDFGL
Sbjct: 619 IISGITRGLVYLHQDSRLRIIHRDLKTSNILLDDNLDPKISDFGL 663