BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia32_contig00015897
         (1280 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe ...   683   0.0  
ref|XP_011087923.1| DNA topoisomerase 2 isoform X2 [Sesamum indi...   670   0.0  
ref|XP_011087914.1| DNA topoisomerase 2 isoform X1 [Sesamum indi...   670   0.0  
gb|KZV36276.1| DNA topoisomerase 2 [Dorcoceras hygrometricum]         628   0.0  
dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]            624   0.0  
gb|EPS67102.1| hypothetical protein M569_07672 [Genlisea aurea]       570   0.0  
gb|EPS73185.1| hypothetical protein M569_01571, partial [Genlise...   565   0.0  
emb|CDP07797.1| unnamed protein product [Coffea canephora]            551   e-180
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...   543   e-177
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...   543   e-177
ref|XP_020113224.1| DNA topoisomerase 2-like [Ananas comosus]         514   e-177
gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]                534   e-173
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]   531   e-173
gb|EOY18139.1| Topoisomerase II isoform 3 [Theobroma cacao]           523   e-172
gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]        519   e-170
gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]        523   e-170
ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]          523   e-169
ref|XP_007009327.2| PREDICTED: DNA topoisomerase 2 [Theobroma ca...   520   e-168
ref|XP_022896608.1| DNA topoisomerase 2 [Olea europaea var. sylv...   520   e-168
ref|XP_019150958.1| PREDICTED: DNA topoisomerase 2 [Ipomoea nil]...   520   e-168

>ref|XP_012849677.1| PREDICTED: DNA topoisomerase 2 [Erythranthe guttata]
 gb|EYU27037.1| hypothetical protein MIMGU_mgv1a000169mg [Erythranthe guttata]
          Length = 1503

 Score =  683 bits (1763), Expect = 0.0
 Identities = 335/422 (79%), Positives = 377/422 (89%), Gaps = 2/422 (0%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D Q IEPTWYVP IP VLVNGSEGIGTGWS+F+PNYNPLDIIANVRHLLN EPME MHPW
Sbjct: 829  DGQMIEPTWYVPIIPTVLVNGSEGIGTGWSSFVPNYNPLDIIANVRHLLNGEPMEAMHPW 888

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF G IEKTATKEAG SYTV+GIIEEVDET+L ITELPIR+WTQDYKEFLES+SAEND
Sbjct: 889  YKGFKGTIEKTATKEAGFSYTVTGIIEEVDETTLTITELPIRRWTQDYKEFLESISAEND 948

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            KSKDPFIEGCRDNS GEI+HF+VY+S  NL  AKQEGL+KKFKLTT++STSNMHLFDSKG
Sbjct: 949  KSKDPFIEGCRDNSGGEIIHFAVYLSETNLLVAKQEGLLKKFKLTTTMSTSNMHLFDSKG 1008

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            VIKKYD+PEQI+EEFF+IRLEFY+KRKKALLANLE DMLKCDNKYRFIRGVV+G+I+VSN
Sbjct: 1009 VIKKYDSPEQILEEFFYIRLEFYEKRKKALLANLELDMLKCDNKYRFIRGVVEGTIVVSN 1068

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RK+ADLFLELK KGFTPFPKKK   E+A+AG+TDD +E+E+N +V I KGVSASDYDYLL
Sbjct: 1069 RKKADLFLELKAKGFTPFPKKKNTPEVAVAGATDDTEETEDNTEVEIAKGVSASDYDYLL 1128

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            SLAIGTLTAEK++ELRDER++L QEVE+LK++TVKSLW  DLDALE+K IE+L  SEKKW
Sbjct: 1129 SLAIGTLTAEKLQELRDERERLTQEVEDLKKSTVKSLWTKDLDALEAKIIEDLKNSEKKW 1188

Query: 198  AENRQRIL-GEAKGTRPVQTKPRKNTKKA-SNKESVVEQMEVSDNTVTETDKVGEVKKPR 25
             E+RQRI  GE K  RP+   PRKNTKKA + KES  E M+VSDNTVTETDKV E+KKPR
Sbjct: 1189 EEDRQRIQGGETKIARPLAKNPRKNTKKATTKKESTAEHMDVSDNTVTETDKVAEIKKPR 1248

Query: 24   GR 19
            G+
Sbjct: 1249 GK 1250


>ref|XP_011087923.1| DNA topoisomerase 2 isoform X2 [Sesamum indicum]
          Length = 1483

 Score =  670 bits (1729), Expect = 0.0
 Identities = 336/420 (80%), Positives = 371/420 (88%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEP+WYVP IPMVLVNGSEGIGTGWS+FIPNYNPLDIIAN+RHLLNDEPM PMHPW
Sbjct: 827  DGQSIEPSWYVPIIPMVLVNGSEGIGTGWSSFIPNYNPLDIIANLRHLLNDEPMVPMHPW 886

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF G IEKTATKEAGNSYTVSGIIEE+DE +L ITELP+RKWTQDYKEFLES+SAEN+
Sbjct: 887  YKGFRGSIEKTATKEAGNSYTVSGIIEELDERTLSITELPVRKWTQDYKEFLESISAENE 946

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            KSKDPFIEGCRDNS GEIV+F VY+S  NL  AKQEGL+KKFKLTTSISTSNMHLFD+KG
Sbjct: 947  KSKDPFIEGCRDNSGGEIVNFLVYLSAENLLIAKQEGLLKKFKLTTSISTSNMHLFDAKG 1006

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            VIKKYDTPEQI+EEFFHIRLEFY+KRK+ LLANLENDMLKC+NK RFI+ VV+ SIIVSN
Sbjct: 1007 VIKKYDTPEQILEEFFHIRLEFYEKRKRVLLANLENDMLKCENKCRFIQCVVESSIIVSN 1066

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            R+RADLFLELKEKGFTPFPKKKTAAE+AIAGS D+A+E+EEN         SASDYDYLL
Sbjct: 1067 RRRADLFLELKEKGFTPFPKKKTAAEVAIAGSLDEAEETEEN--------TSASDYDYLL 1118

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            SLAIGTLTAEK++ELR ERDKLMQEVE LKRATVKSLWM+DLDALESKFIEE NKSEKKW
Sbjct: 1119 SLAIGTLTAEKIQELRAERDKLMQEVENLKRATVKSLWMNDLDALESKFIEEQNKSEKKW 1178

Query: 198  AENRQRILGEAKGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVKKPRGR 19
             + R++I G    +RPVQ  PRKN KKA+NKES   QMEVS +TV E    G++KKP+GR
Sbjct: 1179 EKEREKINGTVNISRPVQKNPRKNNKKATNKES---QMEVSGDTVPEAGNAGDIKKPKGR 1235


>ref|XP_011087914.1| DNA topoisomerase 2 isoform X1 [Sesamum indicum]
          Length = 1484

 Score =  670 bits (1729), Expect = 0.0
 Identities = 336/420 (80%), Positives = 371/420 (88%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEP+WYVP IPMVLVNGSEGIGTGWS+FIPNYNPLDIIAN+RHLLNDEPM PMHPW
Sbjct: 827  DGQSIEPSWYVPIIPMVLVNGSEGIGTGWSSFIPNYNPLDIIANLRHLLNDEPMVPMHPW 886

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF G IEKTATKEAGNSYTVSGIIEE+DE +L ITELP+RKWTQDYKEFLES+SAEN+
Sbjct: 887  YKGFRGSIEKTATKEAGNSYTVSGIIEELDERTLSITELPVRKWTQDYKEFLESISAENE 946

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            KSKDPFIEGCRDNS GEIV+F VY+S  NL  AKQEGL+KKFKLTTSISTSNMHLFD+KG
Sbjct: 947  KSKDPFIEGCRDNSGGEIVNFLVYLSAENLLIAKQEGLLKKFKLTTSISTSNMHLFDAKG 1006

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            VIKKYDTPEQI+EEFFHIRLEFY+KRK+ LLANLENDMLKC+NK RFI+ VV+ SIIVSN
Sbjct: 1007 VIKKYDTPEQILEEFFHIRLEFYEKRKRVLLANLENDMLKCENKCRFIQCVVESSIIVSN 1066

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            R+RADLFLELKEKGFTPFPKKKTAAE+AIAGS D+A+E+EEN         SASDYDYLL
Sbjct: 1067 RRRADLFLELKEKGFTPFPKKKTAAEVAIAGSLDEAEETEEN--------TSASDYDYLL 1118

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            SLAIGTLTAEK++ELR ERDKLMQEVE LKRATVKSLWM+DLDALESKFIEE NKSEKKW
Sbjct: 1119 SLAIGTLTAEKIQELRAERDKLMQEVENLKRATVKSLWMNDLDALESKFIEEQNKSEKKW 1178

Query: 198  AENRQRILGEAKGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVKKPRGR 19
             + R++I G    +RPVQ  PRKN KKA+NKES   QMEVS +TV E    G++KKP+GR
Sbjct: 1179 EKEREKINGTVNISRPVQKNPRKNNKKATNKES---QMEVSGDTVPEAGNAGDIKKPKGR 1235


>gb|KZV36276.1| DNA topoisomerase 2 [Dorcoceras hygrometricum]
          Length = 1455

 Score =  628 bits (1620), Expect = 0.0
 Identities = 314/421 (74%), Positives = 365/421 (86%), Gaps = 1/421 (0%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D Q IEP+WYVP IPMVLVNGSEGIGTGWS+F+PNYNP DIIANVRHLLNDE M+ MHPW
Sbjct: 796  DGQRIEPSWYVPIIPMVLVNGSEGIGTGWSSFVPNYNPKDIIANVRHLLNDEKMDAMHPW 855

Query: 1098 YKGFIGLIEKTATKEAGN-SYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEN 922
            Y+GF G IEKTATKEAG  SYT+SGIIEEVD+ +LRITELPIRKWTQDYKEFLESV+AEN
Sbjct: 856  YRGFRGTIEKTATKEAGGVSYTISGIIEEVDDATLRITELPIRKWTQDYKEFLESVAAEN 915

Query: 921  DKSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSK 742
            +KSKDPFIEGC D+S+G+IVHF V MS +NL +A+QEGL+KKFKLTTSISTSNMHLFDS 
Sbjct: 916  EKSKDPFIEGCSDHSTGDIVHFLVCMSQDNLLQARQEGLLKKFKLTTSISTSNMHLFDSN 975

Query: 741  GVIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVS 562
            G+IKKYDTPEQI+EEFFHIRL+FY+KRKKALLANLEND+LKC+NKY+FIR VV+GSIIVS
Sbjct: 976  GLIKKYDTPEQILEEFFHIRLDFYEKRKKALLANLENDLLKCENKYKFIRCVVEGSIIVS 1035

Query: 561  NRKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYL 382
            NRKRADLF ELKEKGFTPFPKKK++A++ IAGSTDDA+++ EN+  A G G S SDYDYL
Sbjct: 1036 NRKRADLFRELKEKGFTPFPKKKSSADVFIAGSTDDAEDTGENSPGATGSGDSTSDYDYL 1095

Query: 381  LSLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKK 202
            LS+AIGTLT EK++ELR ERDKL+QEVEELK +T+KSLW+ DLDALE K ++EL +SE+K
Sbjct: 1096 LSMAIGTLTLEKLQELRAERDKLLQEVEELKSSTIKSLWLSDLDALEGK-LDELEQSEEK 1154

Query: 201  WAENRQRILGEAKGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVKKPRG 22
                R++ILG+AK TRPV   PRKN KK SNKES  E   +S N V ETD + E KK +G
Sbjct: 1155 IEVERKKILGKAKITRPVLKNPRKNNKKTSNKES-AEPNGISVNPVPETDNIAENKKVKG 1213

Query: 21   R 19
            +
Sbjct: 1214 K 1214


>dbj|BAE06274.1| topoisomerase II [Scutellaria baicalensis]
          Length = 1469

 Score =  624 bits (1610), Expect = 0.0
 Identities = 312/420 (74%), Positives = 356/420 (84%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEPTWYVP IPMVLVNGSEGIGTGWS+++PNYNP+DIIAN+RHLLNDE  EPMHPW
Sbjct: 824  DGQSIEPTWYVPIIPMVLVNGSEGIGTGWSSYVPNYNPVDIIANIRHLLNDEATEPMHPW 883

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF+G +EKTATKEAG SYTVSGIIEEVD+T+L I ELPIR+WTQDYKEFLESVSAEND
Sbjct: 884  YKGFLGSVEKTATKEAGASYTVSGIIEEVDDTTLCIKELPIRRWTQDYKEFLESVSAEND 943

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            KSKDPFIEGCRD S  E+V+F V M P  L  AK+EGL+KKFKLTTSIST NMHLFDSKG
Sbjct: 944  KSKDPFIEGCRDYSGSELVNFLVGMKPEKLEAAKREGLLKKFKLTTSISTCNMHLFDSKG 1003

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            VIKKYDTPEQI+EEFF+IRLE Y+KRKK LL  LE+DMLKCDNKYRFIR VV+GSIIVSN
Sbjct: 1004 VIKKYDTPEQILEEFFYIRLELYEKRKKVLLDILEHDMLKCDNKYRFIRCVVEGSIIVSN 1063

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKR D+F ELKEKGFTPFPKKK  AE+AIAG+TDD +E+EEN++V I  GVS+SDYDYLL
Sbjct: 1064 RKRTDVFRELKEKGFTPFPKKKNRAEVAIAGATDDGEETEENSEVPIAPGVSSSDYDYLL 1123

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            SLAIGTLT EKM+ELR ERDKLMQEVEELK++T +SLW  DLDALE K  EE    E+ W
Sbjct: 1124 SLAIGTLTTEKMQELRAERDKLMQEVEELKQSTARSLWNKDLDALEDKLAEEQKIYEETW 1183

Query: 198  AENRQRILGEAKGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVKKPRGR 19
             +N+++I G+      +Q  PRKN KK + KES VE ME+S+NT TETD   ++KKPRG+
Sbjct: 1184 EKNKRKIHGKTDTLEIIQKNPRKN-KKTTKKESAVE-MEISENTTTETDV--KIKKPRGK 1239


>gb|EPS67102.1| hypothetical protein M569_07672 [Genlisea aurea]
          Length = 1440

 Score =  570 bits (1469), Expect = 0.0
 Identities = 290/418 (69%), Positives = 338/418 (80%), Gaps = 3/418 (0%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEP WY+P IPMVLVNGSEGIGTGWSTFIPNYNP DIIANVRHLLNDE M+ M PW
Sbjct: 823  DGQSIEPIWYMPIIPMVLVNGSEGIGTGWSTFIPNYNPRDIIANVRHLLNDEMMDSMQPW 882

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            Y+GF G IEK  TKEAG  Y VSGIIEE+DET+L++TELPIRKWTQDYKEFLESVS+END
Sbjct: 883  YRGFRGSIEKNTTKEAGTGYNVSGIIEEIDETTLKVTELPIRKWTQDYKEFLESVSSEND 942

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            KSKDPFIEGC D SS  I  F VYMS   L   KQEGL+KKFK+TT+I T+NMHLFD KG
Sbjct: 943  KSKDPFIEGCSDYSSPHIPQFMVYMSAEKLLAVKQEGLLKKFKMTTNIGTTNMHLFDPKG 1002

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            VIKKYDTPEQI+EEF+H+RLE+Y+KRKKALLANLE D+LKC+NK+RFIR VVDGSI+VSN
Sbjct: 1003 VIKKYDTPEQILEEFYHLRLEYYEKRKKALLANLEVDLLKCENKWRFIRCVVDGSIVVSN 1062

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKRADL LELK+KGFTPFPKKK AAE+ +AGSTDD  E+EEN   A  +G    DYDYLL
Sbjct: 1063 RKRADLLLELKQKGFTPFPKKKLAAEVDVAGSTDDVYEAEENGATASHEG----DYDYLL 1118

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            SL+IGTLT EKM+EL  ERDKL+QE E+LKRA+VKSLWM DLDALE K ++EL K+ ++ 
Sbjct: 1119 SLSIGTLTVEKMRELEAERDKLLQEFEDLKRASVKSLWMKDLDALEGK-LDELEKNAEEQ 1177

Query: 198  AENRQRILGEAKGTRPVQTKPRKNTKKASNK-ESVVEQM--EVSDNTVTETDKVGEVK 34
             ++R +++  AK  RPV   PRKN + A+ K +S   Q+  ++SDN   +T K  E K
Sbjct: 1178 EKSRSKVMNNAKLKRPVLKNPRKNKEVANGKAKSAANQVTKQISDN--ADTFKKAEAK 1233


>gb|EPS73185.1| hypothetical protein M569_01571, partial [Genlisea aurea]
          Length = 1258

 Score =  565 bits (1456), Expect = 0.0
 Identities = 285/420 (67%), Positives = 331/420 (78%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEPTWY+P IPM LVNGS+GIGTGWST IPNYNP DIIANVRHLLNDE M+PM PW
Sbjct: 826  DGQSIEPTWYMPIIPMALVNGSDGIGTGWSTSIPNYNPRDIIANVRHLLNDEMMDPMTPW 885

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            Y+G+ G IEK+ATKE    YTV+GIIEEVDET+LRITELP+RKWTQDYKEFLESVSAEND
Sbjct: 886  YRGYRGSIEKSATKEL--VYTVTGIIEEVDETTLRITELPVRKWTQDYKEFLESVSAEND 943

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            KSKDPF++GC D+SS +  HF VYM+  NL  AKQE L+KKFKLT +I T+NMHLFD  G
Sbjct: 944  KSKDPFVQGCSDHSSPQFAHFMVYMTAENLLAAKQENLLKKFKLTANICTTNMHLFDRNG 1003

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
             IKKYDTPEQI+EEFFHIRLE+Y+KRK  LLANLE D+LKC+NK+RFI+ VVDGSI+VSN
Sbjct: 1004 AIKKYDTPEQILEEFFHIRLEYYEKRKATLLANLEIDLLKCENKWRFIKSVVDGSIVVSN 1063

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RK+ADLFLELK KGFTPFPKKK AAE+   GST+D DE+EEN+ V   +  S  DYDYLL
Sbjct: 1064 RKKADLFLELKNKGFTPFPKKKQAAEVDFVGSTEDLDENEENDGVKTSQEGSIGDYDYLL 1123

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            SLAIGTLT EKM ELR ERDKL  + E+LKRATVKSLW+ DLDALE K ++EL K++ + 
Sbjct: 1124 SLAIGTLTVEKMDELRSERDKLSSDFEDLKRATVKSLWIKDLDALEEK-LDELEKADVEK 1182

Query: 198  AENRQRILGEAKGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVKKPRGR 19
             +NR   +G  K ++ V   PRKN K A+     VE M    N   E + V   KKPRG+
Sbjct: 1183 EKNRSNAVGNTKVSKLVLKNPRKNNKAANTNVESVENMRCFVNVKCERNVVS--KKPRGK 1240


>emb|CDP07797.1| unnamed protein product [Coffea canephora]
          Length = 1486

 Score =  551 bits (1419), Expect = e-180
 Identities = 278/426 (65%), Positives = 340/426 (79%), Gaps = 6/426 (1%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEPTWY+P IPMVLVNGSEGIGTGWS++IPNYNP DII N+R LLN+EPMEPM PW
Sbjct: 816  DGQSIEPTWYMPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIIGNIRRLLNNEPMEPMEPW 875

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF G IEKTATKEAG SYTVSGI+EEVDET++R+TELP+RKWTQDYKEFLES+   N+
Sbjct: 876  YKGFRGTIEKTATKEAGASYTVSGIVEEVDETTIRVTELPVRKWTQDYKEFLESIMMGNE 935

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            K KDPFI+  RD++    V+  + MS  NL  AKQEGL+KKFKLTT+ISTSNMHLFDS+G
Sbjct: 936  KVKDPFIKEFRDHTDDTTVYLDIIMSEENLLMAKQEGLLKKFKLTTTISTSNMHLFDSQG 995

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            +IKK+D PEQI+EEFFH+RLEFY+KRKK LL NL+ ++LK DNK RFI  VV+GSIIVSN
Sbjct: 996  IIKKFDNPEQILEEFFHLRLEFYEKRKKVLLDNLQLELLKLDNKVRFILAVVEGSIIVSN 1055

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKRADLFLELKEKGFTPFPKKK + E A+AGS +DA+E+EE+++VA  KGV ASDY+YL+
Sbjct: 1056 RKRADLFLELKEKGFTPFPKKK-SVEAAVAGSIEDAEETEESSEVATSKGVRASDYEYLI 1114

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIG+LT EK++EL  +RDKL  EV++L +AT KSLW  DLDALES+ ++E + S+ + 
Sbjct: 1115 SMAIGSLTLEKVQELCADRDKLKGEVDDLIKATPKSLWTKDLDALESQ-LDEQDISDAQA 1173

Query: 198  AENRQRILGEA------KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEV 37
               R+ +  +A      K TR     PRK  KKASN E   E ME+S ++  ET+ V EV
Sbjct: 1174 EAARKEMRSKAMKDDGPKPTRQAPKNPRKYNKKASNTEPTTEPMEISSSSALETNNVVEV 1233

Query: 36   KKPRGR 19
             KP+G+
Sbjct: 1234 AKPKGK 1239


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score =  543 bits (1399), Expect = e-177
 Identities = 277/427 (64%), Positives = 336/427 (78%), Gaps = 7/427 (1%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEPTWY+P IP VLVNGSEGIGTGWS++IPNYNP DI+AN++ LLN EPMEPM PW
Sbjct: 818  DGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPW 877

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF GLIEKTATKEAG+SYTVSGIIEE++ET+LRITELPIR+WTQDYKEFLES+   ND
Sbjct: 878  YKGFKGLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGND 937

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            K K+PFI+  ++++    VHF + +S  NL  AKQEGLMKKFKLTT+ISTSNMHLFD KG
Sbjct: 938  KIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKG 997

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
             IKKYD PEQI+EEFFH+RLEFY+KRKK  L NLE D+LK DNK RFI GVV G IIVSN
Sbjct: 998  TIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSN 1057

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKR DLFLEL++KGFTPFPKK  A E A+AG+ +D +E+EEN++V   +GV ASDY+YLL
Sbjct: 1058 RKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLL 1117

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIGTLT EK++EL  +RDKL  EVEEL++AT  SLWM+DLDALE K ++E +K++ + 
Sbjct: 1118 SMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALE-KELDEQDKNDAQA 1176

Query: 198  AENRQ----RILGEA--KGTRPVQTKPRK-NTKKASNKESVVEQMEVSDNTVTETDKVGE 40
             E R+    R++ EA  K +R     PRK N KK S  E+V E +  S +  +  + V E
Sbjct: 1177 EEARKELKNRVMSEAGMKASRQAPKNPRKTNAKKPSTSETVTESVAAS-SVGSAMETVPE 1235

Query: 39   VKKPRGR 19
            V KP+GR
Sbjct: 1236 VVKPKGR 1242


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score =  543 bits (1399), Expect = e-177
 Identities = 277/427 (64%), Positives = 336/427 (78%), Gaps = 7/427 (1%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEPTWY+P IP VLVNGSEGIGTGWS++IPNYNP DI+AN++ LLN EPMEPM PW
Sbjct: 818  DGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIKRLLNGEPMEPMDPW 877

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF GLIEKTATKEAG+SYTVSGIIEE++ET+LRITELPIR+WTQDYKEFLES+   ND
Sbjct: 878  YKGFKGLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIRRWTQDYKEFLESIMTGND 937

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            K K+PFI+  ++++    VHF + +S  NL  AKQEGLMKKFKLTT+ISTSNMHLFD KG
Sbjct: 938  KIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTTTISTSNMHLFDPKG 997

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
             IKKYD PEQI+EEFFH+RLEFY+KRKK  L NLE D+LK DNK RFI GVV G IIVSN
Sbjct: 998  TIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVRFILGVVKGEIIVSN 1057

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKR DLFLEL++KGFTPFPKK  A E A+AG+ +D +E+EEN++V   +GV ASDY+YLL
Sbjct: 1058 RKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVVSSRGVRASDYEYLL 1117

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIGTLT EK++EL  +RDKL  EVEEL++AT  SLWM+DLDALE K ++E +K++ + 
Sbjct: 1118 SMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALE-KELDEQDKNDAQA 1176

Query: 198  AENRQ----RILGEA--KGTRPVQTKPRK-NTKKASNKESVVEQMEVSDNTVTETDKVGE 40
             E R+    R++ EA  K +R     PRK N KK S  E+V E +  S +  +  + V E
Sbjct: 1177 EEARKELKNRVMSEAGMKASRQAPKNPRKTNAKKPSTSETVTESVAAS-SVGSAMETVPE 1235

Query: 39   VKKPRGR 19
            V KP+GR
Sbjct: 1236 VVKPKGR 1242


>ref|XP_020113224.1| DNA topoisomerase 2-like [Ananas comosus]
          Length = 536

 Score =  514 bits (1323), Expect = e-177
 Identities = 258/409 (63%), Positives = 319/409 (77%), Gaps = 7/409 (1%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEPTWY+P IPMVL+NGSEGIGTGWS+F+PNYNP DIIANVR LLNDEPM+PM PW
Sbjct: 115  DGQSIEPTWYIPIIPMVLINGSEGIGTGWSSFVPNYNPRDIIANVRRLLNDEPMQPMDPW 174

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            Y+GF GLIEK+ATKEAG +YT++GIIEEVD T+LRI ELP+R+WTQDYKEFLE++   ND
Sbjct: 175  YRGFKGLIEKSATKEAGVTYTITGIIEEVDNTTLRIMELPVRRWTQDYKEFLEALMTGND 234

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            K K+PFI+  R+++    VHF V ++  NL+ A QEGL KKFKLTT+I T+NMHLFDS G
Sbjct: 235  KVKEPFIKDYREHNDDTTVHFEVTLTEENLNIALQEGLEKKFKLTTTIGTTNMHLFDSNG 294

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            VIKKYDTPEQI+E+FFH+RLEFY+KRKK LL NLE D+LK DNK RFI GVV G IIV+N
Sbjct: 295  VIKKYDTPEQILEDFFHLRLEFYEKRKKVLLDNLEMDLLKLDNKVRFILGVVRGEIIVNN 354

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKRA+LF+EL +KGFTPFPKK    ++AI G+T + +E+EE+ ++  G GV ASDY+YLL
Sbjct: 355  RKRAELFIELHQKGFTPFPKKSKGIDVAIVGATTEEEENEESPEMGKG-GVRASDYEYLL 413

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIGTLT EK++EL  ERDKL  EVEEL++AT +SLW+ DLDALE     EL + E+K 
Sbjct: 414  SMAIGTLTLEKVQELCGERDKLESEVEELRKATPRSLWLKDLDALE----RELEEQERKD 469

Query: 198  AE-------NRQRILGEAKGTRPVQTKPRKNTKKASNKESVVEQMEVSD 73
            AE        R + +G A  ++    KPRKNT KA   +   E +E+ +
Sbjct: 470  AEADGARRAMRAKNIGAAAASKQGAKKPRKNTSKAVESDDEDEVLELKE 518


>gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]
          Length = 1515

 Score =  534 bits (1375), Expect = e-173
 Identities = 270/427 (63%), Positives = 333/427 (77%), Gaps = 7/427 (1%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEPTWYVP IP VLVNGSEGIGTGWS +IPNYNP DI+ NV+ LLN EPMEPM PW
Sbjct: 846  DGQSIEPTWYVPVIPTVLVNGSEGIGTGWSCYIPNYNPRDIVENVKRLLNGEPMEPMDPW 905

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF G IEKTATKE G SYTVSGIIEEV+ET+LRI+ELP+R+WTQDYKEFLES+   ND
Sbjct: 906  YKGFKGRIEKTATKEGGVSYTVSGIIEEVNETTLRISELPVRRWTQDYKEFLESIMTGND 965

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            K K+PFI+  R+++    VHF V +S  NL  AKQEGL+KKFKLTT++STSNMHLFD KG
Sbjct: 966  KIKEPFIKDYREHNDDTTVHFEVILSEENLVMAKQEGLLKKFKLTTTVSTSNMHLFDPKG 1025

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            VIKKYD PEQI+EEFFH+RLEFY+KRK+ LL NLE ++LK DNK RFI GVV G IIVSN
Sbjct: 1026 VIKKYDNPEQILEEFFHLRLEFYEKRKRVLLENLELELLKLDNKVRFILGVVKGEIIVSN 1085

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKRADLFLEL++KGFTPFPKK    E  +AG+T+D +E+E+N++    +GV ASDY+YLL
Sbjct: 1086 RKRADLFLELQQKGFTPFPKKTKLVEAVVAGATEDTEENEDNSEALSSRGVRASDYEYLL 1145

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIGTLT EK++EL +++ +L  EV+EL+RAT KSLW  DLDALE +F +E +K++ K 
Sbjct: 1146 SMAIGTLTLEKVQELCNDKQRLDGEVDELRRATSKSLWKKDLDALEKEF-DEQDKNDSKA 1204

Query: 198  AENRQ----RILGEA--KGTRPVQTKPRK-NTKKASNKESVVEQMEVSDNTVTETDKVGE 40
             E R+    +++ EA  K ++PV   PRK NTKK +N  +V    +VS  +  E + + E
Sbjct: 1205 EEARKVMKSKVMKEAGMKDSKPVAKNPRKNNTKKVNNPAAVAASAQVS--STMEIENISE 1262

Query: 39   VKKPRGR 19
              KP+GR
Sbjct: 1263 AAKPKGR 1269


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]
          Length = 1489

 Score =  531 bits (1369), Expect = e-173
 Identities = 273/427 (63%), Positives = 331/427 (77%), Gaps = 7/427 (1%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEPTWYVPTIPMVLVNGSEGIGTGWS+ IPNYNP DIIANVR LLN E MEPM PW
Sbjct: 815  DGQSIEPTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMDPW 874

Query: 1098 YKGFIGLIEKT-ATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEN 922
            Y+GF G IEKT  TK+    YTV GIIEEV+ET+LRI+ELP+RKWTQDYKEFLES+   N
Sbjct: 875  YRGFRGTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMTGN 934

Query: 921  DKSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSK 742
            DK KDPFI+  ++++    VHF V MS  NL  AKQEGL++KFKLTT ISTSNMHLFDS 
Sbjct: 935  DKIKDPFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFDSN 994

Query: 741  GVIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVS 562
            G IKKY+TPEQI+EEFFH+RLEFY+KRK+ LL NLE ++LK +NK RFI GVV G IIVS
Sbjct: 995  GTIKKYETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEIIVS 1054

Query: 561  NRKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYL 382
            NRKRADLF EL +KGFTPFPKK  + EIA+AG+TDD +E+EEN D     GV A+DY+YL
Sbjct: 1055 NRKRADLFHELHQKGFTPFPKKSKSVEIAVAGATDDTEEAEENTDAVSKGGVRATDYEYL 1114

Query: 381  LSLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKK 202
            LS+AIGTLT EK++EL  +RDKL + V++LK+AT K+LW+ DLDALE + ++E +K++ +
Sbjct: 1115 LSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERE-LDEQDKNDAR 1173

Query: 201  WAENRQ----RILGEA--KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGE 40
              E R+    R++ EA  K +R     PRKN KKA+N E   E M+VS ++  E + V E
Sbjct: 1174 AEETRKQLKSRVMSEAGMKVSRQAPKNPRKNNKKANNAEPAAETMDVSASSAMEMESVPE 1233

Query: 39   VKKPRGR 19
            V KP+GR
Sbjct: 1234 VVKPKGR 1240


>gb|EOY18139.1| Topoisomerase II isoform 3 [Theobroma cacao]
          Length = 1244

 Score =  523 bits (1348), Expect = e-172
 Identities = 265/422 (62%), Positives = 325/422 (77%), Gaps = 2/422 (0%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEP WYVP IPMVLVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E MEPMHPW
Sbjct: 812  DGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPW 871

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            Y+GF G IEKTA+KEAG +YT++GIIEEVDET+LRITELP+R+WTQDY+EFLES+   ND
Sbjct: 872  YRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND 931

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
                PFI+  R  S    V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG
Sbjct: 932  ----PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKG 987

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            +IKKYDTPEQI+EEFFH+R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+N
Sbjct: 988  MIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNN 1047

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKRADLFLEL+ KGFTPFPKK    E+A+AG+TDD +E+EEN++V+  KG+ ASDYDYLL
Sbjct: 1048 RKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVS-AKGLQASDYDYLL 1106

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIG+LT EK++EL  +RDKL QEVE+L++AT KSLW+ DLD LE +  E+   ++ + 
Sbjct: 1107 SMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQAEE 1166

Query: 198  AENRQRILGEA--KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVKKPR 25
            A    +  GEA  +  R     PRK  KK  N E+V E  ++S ++  ET+      KP+
Sbjct: 1167 AAKLVKGRGEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETETAPAAVKPK 1226

Query: 24   GR 19
            GR
Sbjct: 1227 GR 1228


>gb|EOY18138.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
          Length = 1285

 Score =  519 bits (1337), Expect = e-170
 Identities = 265/423 (62%), Positives = 325/423 (76%), Gaps = 3/423 (0%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEP WYVP IPMVLVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E MEPMHPW
Sbjct: 623  DGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPW 682

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            Y+GF G IEKTA+KEAG +YT++GIIEEVDET+LRITELP+R+WTQDY+EFLES+   ND
Sbjct: 683  YRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND 742

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
                PFI+  R  S    V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG
Sbjct: 743  ----PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKG 798

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            +IKKYDTPEQI+EEFFH+R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+N
Sbjct: 799  MIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNN 858

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKRADLFLEL+ KGFTPFPKK    E+A+AG+TDD +E+EEN++V+  KG+ ASDYDYLL
Sbjct: 859  RKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVS-AKGLQASDYDYLL 917

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIG+LT EK++EL  +RDKL QEVE+L++AT KSLW+ DLD LE +  E+   ++ + 
Sbjct: 918  SMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQAEE 977

Query: 198  AENRQRILGEA--KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVK-KP 28
            A    +  GEA  +  R     PRK  KK  N E+V E  ++S ++  ET +      KP
Sbjct: 978  AAKLVKGRGEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETAETAPAAVKP 1037

Query: 27   RGR 19
            +GR
Sbjct: 1038 KGR 1040


>gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
          Length = 1473

 Score =  523 bits (1348), Expect = e-170
 Identities = 265/422 (62%), Positives = 325/422 (77%), Gaps = 2/422 (0%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEP WYVP IPMVLVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E MEPMHPW
Sbjct: 812  DGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPW 871

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            Y+GF G IEKTA+KEAG +YT++GIIEEVDET+LRITELP+R+WTQDY+EFLES+   ND
Sbjct: 872  YRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND 931

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
                PFI+  R  S    V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG
Sbjct: 932  ----PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDSKG 987

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            +IKKYDTPEQI+EEFFH+R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+N
Sbjct: 988  MIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNN 1047

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKRADLFLEL+ KGFTPFPKK    E+A+AG+TDD +E+EEN++V+  KG+ ASDYDYLL
Sbjct: 1048 RKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVS-AKGLQASDYDYLL 1106

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIG+LT EK++EL  +RDKL QEVE+L++AT KSLW+ DLD LE +  E+   ++ + 
Sbjct: 1107 SMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQAEE 1166

Query: 198  AENRQRILGEA--KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVKKPR 25
            A    +  GEA  +  R     PRK  KK  N E+V E  ++S ++  ET+      KP+
Sbjct: 1167 AAKLVKGRGEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETETAPAAVKPK 1226

Query: 24   GR 19
            GR
Sbjct: 1227 GR 1228


>ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]
          Length = 1475

 Score =  523 bits (1347), Expect = e-169
 Identities = 264/422 (62%), Positives = 324/422 (76%), Gaps = 2/422 (0%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEP WYVP IPMVLVNGSEGIGTGWS++IPNYNP DI+ANVR LLNDE MEPMHPW
Sbjct: 812  DGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNDEQMEPMHPW 871

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            Y+GF G IEKTA+KEAG +YT++G+IEEVDE +LRITELP+R+WTQDY+EFLES+   ND
Sbjct: 872  YRGFKGNIEKTASKEAGVTYTITGVIEEVDEATLRITELPVRRWTQDYREFLESIITGND 931

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
                PFI+  R  S    V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG
Sbjct: 932  ----PFIKEFRQYSDDTTVEFEVILTEENMMMAKQEGLLKKFKLTTTISTSNMHLFDSKG 987

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            +IKKYDTPEQI+EEFFH+R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+N
Sbjct: 988  MIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNN 1047

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKRADLFLEL+ KGFTPFPKK    E+A+AG+TDD +E+EEN++V+  KGV ASDYDYLL
Sbjct: 1048 RKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVS-AKGVQASDYDYLL 1106

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIG+LT EK++EL  +RDKL QEVE+L++AT KSLW+ DLD LE +  E+   ++ + 
Sbjct: 1107 SMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDKAAQAEE 1166

Query: 198  AENRQRILGEA--KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVKKPR 25
            A    +   EA  +  R     PRK  KK  N E+V E  ++S ++  ET+      KP+
Sbjct: 1167 AAKLVKGRAEAGKRAQRQAPKIPRKINKKEKNAETVTETSDISSSSAMETENAPAAVKPK 1226

Query: 24   GR 19
            GR
Sbjct: 1227 GR 1228


>ref|XP_007009327.2| PREDICTED: DNA topoisomerase 2 [Theobroma cacao]
          Length = 1473

 Score =  520 bits (1340), Expect = e-168
 Identities = 264/422 (62%), Positives = 323/422 (76%), Gaps = 2/422 (0%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEP WYVP IPMVLVNGSEGIGTGWS++IPNYNP DI+ANVR LLN E MEPMHPW
Sbjct: 812  DGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMHPW 871

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            Y+GF G IEKTA+KEAG +YT++GIIEEVDET+LRITELP+R+WTQDY+EFLES+   ND
Sbjct: 872  YRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITGND 931

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
                PFI+  R  S    V F V ++  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG
Sbjct: 932  ----PFIKEFRQYSDDTTVEFEVILTEENMMMAKQEGLLKKFKLTTTISTSNMHLFDSKG 987

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            +IKKYD PEQI+EEFFH+R EFY+KRKK LL NLE ++LK +NK RFI GVV G IIV+N
Sbjct: 988  MIKKYDAPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIVNN 1047

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            RKRADLFLEL+ KGFTPFPKK    E+A+AG+TDD +E+EEN++V+  KGV ASDYDYLL
Sbjct: 1048 RKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVS-AKGVQASDYDYLL 1106

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S+AIG+LT EK++EL  +RDKL QEVE+L++AT  SLW+ DLD LE +  E+   ++ + 
Sbjct: 1107 SMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPMSLWLKDLDNLEIQLDEQDKAAQAEE 1166

Query: 198  AENRQRILGEA--KGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVGEVKKPR 25
            A    +  GEA  +  R     PRK  KK  N E+V E  ++S ++  ET+      KP+
Sbjct: 1167 AAKLVKGRGEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETETAPAAVKPK 1226

Query: 24   GR 19
            GR
Sbjct: 1227 GR 1228


>ref|XP_022896608.1| DNA topoisomerase 2 [Olea europaea var. sylvestris]
          Length = 1459

 Score =  520 bits (1339), Expect = e-168
 Identities = 260/411 (63%), Positives = 325/411 (79%), Gaps = 2/411 (0%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D Q+IEPTWYVP IPMVLVNGSEGIGTGWS+F+PNYNP DIIANVRH+LNDEPMEPM PW
Sbjct: 811  DGQTIEPTWYVPIIPMVLVNGSEGIGTGWSSFVPNYNPRDIIANVRHMLNDEPMEPMDPW 870

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF G IEKTATKEAG +YT +GIIEEV +T+LRITELPIR+WTQDYK++LES+     
Sbjct: 871  YKGFSGTIEKTATKEAGATYTATGIIEEVSDTTLRITELPIRRWTQDYKDYLESLY---- 926

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
                PFIE  R+  + + V+F + +S  N+  AKQEGL+KKFKLTT+ISTSNMHLFDSKG
Sbjct: 927  ----PFIEEVREYHTTDSVNFEIDLSEENMMIAKQEGLLKKFKLTTTISTSNMHLFDSKG 982

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            VIKKYDTPE+I+E+F+ IR EFY+KRKK L+ NLE ++L  +NK RFI  VV+G IIVSN
Sbjct: 983  VIKKYDTPEKILEDFYSIRFEFYEKRKKVLMDNLERELLILENKVRFILNVVEGKIIVSN 1042

Query: 558  RKRADLFLELKEKGFTPFPKKKTAAEIAIAGSTDDADESEENNDVAIGKGVSASDYDYLL 379
            R+RADL LELK+KGFTPFPKK    E+++AGS+D  +E+EEN+D+A  +GV ASDYDYLL
Sbjct: 1043 RRRADLVLELKDKGFTPFPKKTKTVEVSVAGSSDVPEETEENSDMANSQGVRASDYDYLL 1102

Query: 378  SLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEELNKSEKKW 199
            S++IG+LT EK++EL + RDKL+QEVEE+++AT+KSLW+ DLDALE++ ++E +K +   
Sbjct: 1103 SMSIGSLTIEKVQELCNNRDKLIQEVEEMRQATIKSLWIKDLDALETE-LDEQDKRDALA 1161

Query: 198  AENRQRILGE--AKGTRPVQTKPRKNTKKASNKESVVEQMEVSDNTVTETD 52
             E+   I  +   K  +P    PRKN KK    ESVVE ME+S N+  E D
Sbjct: 1162 EEDELEIKPKRGRKAPKPAMKNPRKNNKKVGKTESVVEPMEISTNSEIEKD 1212


>ref|XP_019150958.1| PREDICTED: DNA topoisomerase 2 [Ipomoea nil]
 ref|XP_019150963.1| PREDICTED: DNA topoisomerase 2 [Ipomoea nil]
          Length = 1485

 Score =  520 bits (1339), Expect = e-168
 Identities = 268/428 (62%), Positives = 327/428 (76%), Gaps = 8/428 (1%)
 Frame = -3

Query: 1278 DRQSIEPTWYVPTIPMVLVNGSEGIGTGWSTFIPNYNPLDIIANVRHLLNDEPMEPMHPW 1099
            D QSIEPTWY+P IPMVLVNG EGIGTGWS++IPNYNP DI+ NVR LLNDEPMEPM PW
Sbjct: 816  DGQSIEPTWYIPIIPMVLVNGCEGIGTGWSSYIPNYNPRDIVDNVRRLLNDEPMEPMDPW 875

Query: 1098 YKGFIGLIEKTATKEAGNSYTVSGIIEEVDETSLRITELPIRKWTQDYKEFLESVSAEND 919
            YKGF G+IEKTATKEAG +YT+SGIIEEVDET+LRI ELPIR+WT+DYK+FL S+ A ND
Sbjct: 876  YKGFQGIIEKTATKEAGVTYTISGIIEEVDETTLRIVELPIRRWTEDYKQFLSSMMASND 935

Query: 918  KSKDPFIEGCRDNSSGEIVHFSVYMSPNNLSEAKQEGLMKKFKLTTSISTSNMHLFDSKG 739
            K KDPFI+  R+      VHF + +S  NL  AK EGL+K+FKLTT+ISTSNMHLFDS+G
Sbjct: 936  KVKDPFIKEMREYHDVNTVHFEIELSEENLMLAKDEGLLKRFKLTTTISTSNMHLFDSRG 995

Query: 738  VIKKYDTPEQIIEEFFHIRLEFYDKRKKALLANLENDMLKCDNKYRFIRGVVDGSIIVSN 559
            VIKKYDTPEQI+EEF+ IRLEFY+KRK+ LL NLE ++L+ DNK RFI GVV G IIVSN
Sbjct: 996  VIKKYDTPEQILEEFYKIRLEFYEKRKRVLLENLETELLRLDNKVRFILGVVKGEIIVSN 1055

Query: 558  RKRADLFLELKEKGFTPFPKK-KTAAEIAIAGSTDDADESEENNDVAIGK-GVSASDYDY 385
            RKRA+LF EL+EKGFTPFPKK K A  +A A S+D+A+ESEE+      K GV ASDYDY
Sbjct: 1056 RKRAELFQELREKGFTPFPKKSKVADAVAAAESSDEAEESEESAGATRAKGGVQASDYDY 1115

Query: 384  LLSLAIGTLTAEKMKELRDERDKLMQEVEELKRATVKSLWMHDLDALESKFIEE--LNKS 211
            LLS+AIGTLT EK++EL  ERD L +EVE ++ AT KSLW+ DLDALE +  E+  L ++
Sbjct: 1116 LLSMAIGTLTLEKVQELCAERDGLNEEVECMRNATPKSLWLKDLDALERQLDEQDKLEEA 1175

Query: 210  EKKWAENRQRILGEAKGTRP----VQTKPRKNTKKASNKESVVEQMEVSDNTVTETDKVG 43
             +   + + ++  +A    P       KP ++ K A+ +E+  E MEVS  +  +TDK  
Sbjct: 1176 GEAAIKTKSKVASKAGPAEPRRQAAAKKPPRSKKVATQEETSAEPMEVSAGSAMDTDKGP 1235

Query: 42   EVKKPRGR 19
            EV KP+GR
Sbjct: 1236 EVAKPKGR 1243