BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Rehmannia30_contig00027449
         (2344 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]                889   0.0  
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]   875   0.0  
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...   868   0.0  
emb|CBI24922.3| unnamed protein product, partial [Vitis vinifera]     866   0.0  
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...   868   0.0  
emb|CDP07797.1| unnamed protein product [Coffea canephora]            858   0.0  
ref|XP_010023597.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus g...   846   0.0  
ref|XP_020703085.1| DNA topoisomerase 2-like [Dendrobium catenat...   840   0.0  
ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus g...   843   0.0  
ref|XP_011013333.1| PREDICTED: DNA topoisomerase 2-like isoform ...   839   0.0  
ref|XP_011013332.1| PREDICTED: DNA topoisomerase 2-like isoform ...   837   0.0  
gb|PNT56778.1| hypothetical protein POPTR_001G264000v3 [Populus ...   837   0.0  
ref|XP_011013331.1| PREDICTED: DNA topoisomerase 2-like isoform ...   837   0.0  
gb|PNT56779.1| hypothetical protein POPTR_001G264000v3 [Populus ...   835   0.0  
ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Z...   835   0.0  
ref|XP_011013328.1| PREDICTED: DNA topoisomerase 2-like isoform ...   835   0.0  
ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Z...   831   0.0  
ref|XP_002298421.2| DNA topoisomerase family protein [Populus tr...   831   0.0  
gb|PHU30239.1| DNA topoisomerase 2 [Capsicum chinense]                818   0.0  
ref|XP_011025468.1| PREDICTED: DNA topoisomerase 2-like isoform ...   828   0.0  

>gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]
          Length = 1515

 Score =  889 bits (2296), Expect = 0.0
 Identities = 477/809 (58%), Positives = 583/809 (72%), Gaps = 41/809 (5%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LKIP+FL+EFITPI+KAT + G+V+SFYS+PEYE WK+SL GN SGWSIKYYKGLGTSTS
Sbjct: 588  LKIPSFLIEFITPIVKATHKNGKVMSFYSMPEYEQWKESLGGNASGWSIKYYKGLGTSTS 647

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGKEYF+DLEKH+KDF+W+D++D DAI+LAFSK KI+ARK WL+++EPGTYLDQKEK I
Sbjct: 648  KEGKEYFKDLEKHRKDFMWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLI 707

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDFV+KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAKVAQ SGYVSE
Sbjct: 708  KYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSE 767

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA TI+GMAQDY+GSNNINLLQPNGQFGTRHQGGKDHASARYIYT LSPI
Sbjct: 768  HSAYHHGEQSLAGTIIGMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPI 827

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YLNEDGQS+EPTWYVPVIP VLVNG+EGIGTGWS YIPNYNPRDIV
Sbjct: 828  TRFLFPKDDDILLDYLNEDGQSIEPTWYVPVIPTVLVNGSEGIGTGWSCYIPNYNPRDIV 887

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
             NV+  LN EPMEPM PWYKGFKG IE T TK+ G SY V GIIEEVN+TT+RI+ELPVR
Sbjct: 888  ENVKRLLNGEPMEPMDPWYKGFKGRIEKTATKEGGVSYTVSGIIEEVNETTLRISELPVR 947

Query: 1079 KSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKF 1258
            + T++YK+FL+ +++   + KE FIKD+RE NDD TVHFE+ +SE+NL MAK+EGL++KF
Sbjct: 948  RWTQDYKEFLESIMTGNDKIKEPFIKDYREHNDDTTVHFEVILSEENLVMAKQEGLLKKF 1007

Query: 1259 KLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXX 1438
            KL+TT+STSNMHLF+PKGV+ KY +PE+I+EEF  LRLEFYEKRK  +L           
Sbjct: 1008 KLTTTVSTSNMHLFDPKGVIKKYDNPEQILEEFFHLRLEFYEKRKRVLLENLELELLKLD 1067

Query: 1439 NKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNA-------------------- 1558
            NKVRFI  V++G+II+ NRKR+DL  EL+QK FTPFP+                      
Sbjct: 1068 NKVRFILGVVKGEIIVSNRKRADLFLELQQKGFTPFPKKTKLVEAVVAGATEDTEENEDN 1127

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         YEYLLSM IGTLT+EKVQELC  +++L+ EVD LR AT KSLW KDL
Sbjct: 1128 SEALSSRGVRASDYEYLLSMAIGTLTLEKVQELCNDKQRLDGEVDELRRATSKSLWKKDL 1187

Query: 1739 DSLEQKLNLQSKIYDMPEK-RLEVNAEISKR-----PKRTMRKKQESSEKKANNKDGLAE 1900
            D+LE++ + Q K     E+ R  + +++ K       K   +  ++++ KK NN   +A 
Sbjct: 1188 DALEKEFDEQDKNDSKAEEARKVMKSKVMKEAGMKDSKPVAKNPRKNNTKKVNNPAAVAA 1247

Query: 1901 KHTVPSDC-TGKVPEAVELEGITTGRDEISTPNPPSL----DVNEDRGLEQKE------- 2044
               V S      + EA + +G    R   +    P+L    D ++D  LE KE       
Sbjct: 1248 SAQVSSTMEIENISEAAKPKGRGGPRKAPAKKGKPALVDSDDEDDDEILELKERLAAYNL 1307

Query: 2045 -EQPKQSSS-PDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAE 2218
               P+QSS+ P  + E +  +++   ++ ++  SA    A I EISD E D  N +Q  +
Sbjct: 1308 DSSPEQSSAGPVAAMETESGIVRAKNKETSKMVSAQK-KATITEISDDE-DNRNDEQ-MK 1364

Query: 2219 TVIEISDSEVVCEDEVPNTRINNPSGDEK 2305
            T++E  D E   E  VP  R     G  K
Sbjct: 1365 TIMENEDFEP--EVVVPAGRKGGKRGQTK 1391


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]
          Length = 1489

 Score =  875 bits (2261), Expect = 0.0
 Identities = 470/789 (59%), Positives = 567/789 (71%), Gaps = 40/789 (5%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LKIP+FL+EFITPI+KAT R G+VLSFYS+PEYE+WK+SL GN SGWSIKYYKGLGTSTS
Sbjct: 557  LKIPSFLVEFITPIVKATHRNGRVLSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTS 616

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGKEYF+DL KHKKDF+W+D+KD DAIELAFSK KI+ RK WL++++PGTYLDQKEK I
Sbjct: 617  KEGKEYFKDLGKHKKDFMWVDEKDGDAIELAFSKKKIEERKNWLRQFQPGTYLDQKEKLI 676

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDFV+KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNFIKEAK+AQ SGYVSE
Sbjct: 677  KYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKIAQFSGYVSE 736

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTRHQGGKDHASARYIYT LSPI
Sbjct: 737  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRHQGGKDHASARYIYTRLSPI 796

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YLNEDGQS+EPTWYVP IPMVLVNG+EGIGTGWS+ IPNYNPRDI+
Sbjct: 797  TRFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDII 856

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTN-TKDAGKSYVVKGIIEEVNKTTVRITELPV 1075
            ANVR  LN E MEPM PWY+GF+GTIE T+ TK     Y VKGIIEEVN+TT+RI+ELPV
Sbjct: 857  ANVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPV 916

Query: 1076 RKSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEK 1255
            RK T++YK+FL+ +++   + K+ FIKD++E NDD TVHFE+ MSE+NL MAK+EGL++K
Sbjct: 917  RKWTQDYKEFLESIMTGNDKIKDPFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQK 976

Query: 1256 FKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXX 1435
            FKL+T ISTSNMHLF+  G + KY +PE+I+EEF  LRLEFYEKRK  +L          
Sbjct: 977  FKLTTKISTSNMHLFDSNGTIKKYETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKL 1036

Query: 1436 XNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNA------------------- 1558
             NKVRFI  V++G+II+ NRKR+DL  EL QK FTPFP+ +                   
Sbjct: 1037 ENKVRFILGVVRGEIIVSNRKRADLFHELHQKGFTPFPKKSKSVEIAVAGATDDTEEAEE 1096

Query: 1559 -XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKD 1735
                          YEYLLSM IGTLT+EKVQELCA R KLN  VD L+ ATPK+LW+ D
Sbjct: 1097 NTDAVSKGGVRATDYEYLLSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITD 1156

Query: 1736 LDSLEQKLNLQSKIYDMPEK-----RLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAE 1900
            LD+LE++L+ Q K     E+     +  V +E   +  R   K    + KKANN +  AE
Sbjct: 1157 LDALERELDEQDKNDARAEETRKQLKSRVMSEAGMKVSRQAPKNPRKNNKKANNAEPAAE 1216

Query: 1901 KHTVPSDCT---GKVPEAVELEGITTGR------DEISTPNPPSLDVNEDRGLEQKEEQP 2053
               V +        VPE V+ +G    R       E+ T      D +E   L+++    
Sbjct: 1217 TMDVSASSAMEMESVPEVVKPKGRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAY 1276

Query: 2054 KQSSSPDTSREPKMSVLQVP---PEDNTRRNSADNLN-APIIEISDTEVDCENKQQTAET 2221
               SSPD S   +  V QVP    ++ +RR +A     A   EISD + D E+ +     
Sbjct: 1277 NLESSPDGSAAMEAEVPQVPAARKKEPSRRAAAQKKPLASFTEISDDDEDDEDFE----- 1331

Query: 2222 VIEISDSEV 2248
            V E+S S+V
Sbjct: 1332 VEEVSASDV 1340


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score =  868 bits (2244), Expect = 0.0
 Identities = 464/797 (58%), Positives = 568/797 (71%), Gaps = 43/797 (5%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LKIP+FL+EFITPI+KAT + G+VLSFYS+PEYE+WK  L GN SGWSIKYYKGLGTSTS
Sbjct: 561  LKIPSFLVEFITPIVKATHKNGKVLSFYSMPEYESWKX-LGGNASGWSIKYYKGLGTSTS 619

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGKEYF+DL KHKKDFLW+D +D DAIELAFSK KI+ARK WL+++EPGT LDQKEK I
Sbjct: 620  KEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLI 679

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDFV+KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRN IKEAKVAQ SGYVSE
Sbjct: 680  KYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSE 739

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSL +TI+GMAQDY+GSNNINL QPNGQFGTRHQGGKDHASARYIYT LSPI
Sbjct: 740  HSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPI 799

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K DD LL YLNEDGQS+EPTWY+P+IP VLVNG+EGIGTGWS+YIPNYNPRDIV
Sbjct: 800  TRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIV 859

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN++  LN EPMEPM PWYKGFKG IE T TK+AG SY V GIIEE+N+TT+RITELP+R
Sbjct: 860  ANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIR 919

Query: 1079 KSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKF 1258
            + T++YK+FL+ +++   + KE FIKD++E NDD TVHFEI +SE+NL MAK+EGL++KF
Sbjct: 920  RWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKF 979

Query: 1259 KLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXX 1438
            KL+TTISTSNMHLF+PKG + KY +PE+I+EEF  LRLEFYEKRK   L           
Sbjct: 980  KLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLD 1039

Query: 1439 NKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNA-------------------- 1558
            NKVRFI  V++G+II+ NRKR DL  EL+QK FTPFP+                      
Sbjct: 1040 NKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEEN 1099

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         YEYLLSM IGTLT+EKVQELC+ R KLN EV+ LR ATP SLW+ DL
Sbjct: 1100 SEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDL 1159

Query: 1739 DSLEQKLNLQS-------------KIYDMPEKRLEVNAEISKRPKRTMRKKQESSEKKAN 1879
            D+LE++L+ Q              K   M E  ++ + +  K P++T  KK  +SE    
Sbjct: 1160 DALEKELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKNPRKTNAKKPSTSETVTE 1219

Query: 1880 NKDGLAEKHTVPSDCTGKVPEAVELEGITTGRDE---ISTPNPPSLDVNEDR----GLEQ 2038
            +    +    + +     VPE V+ +G   GR +       N   +D +ED      L++
Sbjct: 1220 SVAASSVGSAMET-----VPEVVKPKG-RGGRPKKAPAKKDNMRLVDSDEDDVDVIELKE 1273

Query: 2039 KEEQPKQSSSPDTSREPKMSVLQVP--PEDNTRRNSADNLNAPIIEISDTEVDCENKQQT 2212
            +       SSP+ S   +  V +VP   ++ ++R +A    +   EISD     ++    
Sbjct: 1274 RLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQKQPSSYTEISD-----DDDGMD 1328

Query: 2213 AETVIEISDSEVVCEDE 2263
             +T+ E S  E+V +++
Sbjct: 1329 VQTIREESIGEIVSDED 1345


>emb|CBI24922.3| unnamed protein product, partial [Vitis vinifera]
          Length = 1452

 Score =  866 bits (2238), Expect = 0.0
 Identities = 465/769 (60%), Positives = 560/769 (72%), Gaps = 20/769 (2%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LKIP+FL+EFITPI+KAT R G+VLSFYS+PEYE+WK+SL GN SGWSIKYYKGLGTSTS
Sbjct: 557  LKIPSFLVEFITPIVKATHRNGRVLSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTS 616

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGKEYF+DL KHKKDF+W+D+KD DAIELAFSK KI+ RK WL++++PGTYLDQKEK I
Sbjct: 617  KEGKEYFKDLGKHKKDFMWVDEKDGDAIELAFSKKKIEERKNWLRQFQPGTYLDQKEKLI 676

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDFV+KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNFIKEAK+AQ SGYVSE
Sbjct: 677  KYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKIAQFSGYVSE 736

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTRHQGGKDHASARYIYT LSPI
Sbjct: 737  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRHQGGKDHASARYIYTRLSPI 796

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YLNEDGQS+EPTWYVP IPMVLVNG+EGIGTGWS+ IPNYNPRDI+
Sbjct: 797  TRFLFPKDDDILLDYLNEDGQSIEPTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDII 856

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTN-TKDAGKSYVVKGIIEEVNKTTVRITELPV 1075
            ANVR  LN E MEPM PWY+GF+GTIE T+ TK     Y VKGIIEEVN+TT+RI+ELPV
Sbjct: 857  ANVRRLLNGEMMEPMDPWYRGFRGTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPV 916

Query: 1076 RKSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEK 1255
            RK T++YK+FL+ +++   + K+ FIKD++E NDD TVHFE+ MSE+NL MAK+EGL++K
Sbjct: 917  RKWTQDYKEFLESIMTGNDKIKDPFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQK 976

Query: 1256 FKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXX 1435
            FKL+T ISTSNMHLF+  G + KY +PE+I+EEF  LRLEFYEKRK  +L          
Sbjct: 977  FKLTTKISTSNMHLFDSNGTIKKYETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKL 1036

Query: 1436 XNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNAXXXXXXXXXXXXXYEYLLS 1615
             NKVRFI  V++G+II+ NRKR+DL  EL QK                      YEYLLS
Sbjct: 1037 ENKVRFILGVVRGEIIVSNRKRADLFHELHQK-----------------VRATDYEYLLS 1079

Query: 1616 MPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSLEQKLNLQSKIYDMPEK 1795
            M IGTLT+EKVQELCA R KLN  VD L+ ATPK+LW+ DLD+LE++L+ Q K     E+
Sbjct: 1080 MAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKNDARAEE 1139

Query: 1796 -----RLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDCT---GKVPEAVE 1951
                 +  V +E   +  R   K    + KKANN +  AE   V +        VPE V+
Sbjct: 1140 TRKQLKSRVMSEAGMKVSRQAPKNPRKNNKKANNAEPAAETMDVSASSAMEMESVPEVVK 1199

Query: 1952 LEGITTGR------DEISTPNPPSLDVNEDRGLEQKEEQPKQSSSPDTSREPKMSVLQVP 2113
             +G    R       E+ T      D +E   L+++       SSPD S   +  V QVP
Sbjct: 1200 PKGRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEAEVPQVP 1259

Query: 2114 ---PEDNTRRNSADNLN-APIIEISDTEVDCENKQQTAETVIEISDSEV 2248
                ++ +RR +A     A   EISD + D E+ +     V E+S S+V
Sbjct: 1260 AARKKEPSRRAAAQKKPLASFTEISDDDEDDEDFE-----VEEVSASDV 1303


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score =  868 bits (2242), Expect = 0.0
 Identities = 464/798 (58%), Positives = 569/798 (71%), Gaps = 44/798 (5%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LKIP+FL+EFITPI+KAT + G+VLSFYS+PEYE+WK  L GN SGWSIKYYKGLGTSTS
Sbjct: 561  LKIPSFLVEFITPIVKATHKNGKVLSFYSMPEYESWKX-LGGNASGWSIKYYKGLGTSTS 619

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGKEYF+DL KHKKDFLW+D +D DAIELAFSK KI+ARK WL+++EPGT LDQKEK I
Sbjct: 620  KEGKEYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLI 679

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDFV+KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRN IKEAKVAQ SGYVSE
Sbjct: 680  KYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSE 739

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSL +TI+GMAQDY+GSNNINL QPNGQFGTRHQGGKDHASARYIYT LSPI
Sbjct: 740  HSAYHHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPI 799

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K DD LL YLNEDGQS+EPTWY+P+IP VLVNG+EGIGTGWS+YIPNYNPRDIV
Sbjct: 800  TRFLFPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIV 859

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN++  LN EPMEPM PWYKGFKG IE T TK+AG SY V GIIEE+N+TT+RITELP+R
Sbjct: 860  ANIKRLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIR 919

Query: 1079 KSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKF 1258
            + T++YK+FL+ +++   + KE FIKD++E NDD TVHFEI +SE+NL MAK+EGL++KF
Sbjct: 920  RWTQDYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKF 979

Query: 1259 KLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXX 1438
            KL+TTISTSNMHLF+PKG + KY +PE+I+EEF  LRLEFYEKRK   L           
Sbjct: 980  KLTTTISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLD 1039

Query: 1439 NKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNA-------------------- 1558
            NKVRFI  V++G+II+ NRKR DL  EL+QK FTPFP+                      
Sbjct: 1040 NKVRFILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEEN 1099

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         YEYLLSM IGTLT+EKVQELC+ R KLN EV+ LR ATP SLW+ DL
Sbjct: 1100 SEVVSSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDL 1159

Query: 1739 DSLEQKLNLQS-------------KIYDMPEKRLEVNAEISKRPKRTMRKKQESSEKKAN 1879
            D+LE++L+ Q              K   M E  ++ + +  K P++T  KK  +SE    
Sbjct: 1160 DALEKELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKNPRKTNAKKPSTSETVTE 1219

Query: 1880 NKDGLAEKHTVPSDCTGKVPEAVELEGITTGRDEIS----TPNPPSLDVNEDR----GLE 2035
            +    +    + +     VPE V+ +G   GR + +      N   +D +ED      L+
Sbjct: 1220 SVAASSVGSAMET-----VPEVVKPKG-RGGRPKKAPAKKQDNMRLVDSDEDDVDVIELK 1273

Query: 2036 QKEEQPKQSSSPDTSREPKMSVLQVP--PEDNTRRNSADNLNAPIIEISDTEVDCENKQQ 2209
            ++       SSP+ S   +  V +VP   ++ ++R +A    +   EISD     ++   
Sbjct: 1274 ERLAAYNLDSSPEQSAVMETEVAKVPAKKKEPSKRAAAQKQPSSYTEISD-----DDDGM 1328

Query: 2210 TAETVIEISDSEVVCEDE 2263
              +T+ E S  E+V +++
Sbjct: 1329 DVQTIREESIGEIVSDED 1346


>emb|CDP07797.1| unnamed protein product [Coffea canephora]
          Length = 1486

 Score =  858 bits (2216), Expect = 0.0
 Identities = 452/787 (57%), Positives = 556/787 (70%), Gaps = 39/787 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LKIP+FL+EFITPI+KAT + G+VLSFY++PEYE+WK+SL GN +GWSIKYYKGLGTSTS
Sbjct: 558  LKIPSFLVEFITPIVKATHKNGRVLSFYTMPEYESWKESLSGNATGWSIKYYKGLGTSTS 617

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGKEYF+DL KHKKDF+W+D  D +AIELAFSK KI+ARK WL+++EPGTYLDQKEK I
Sbjct: 618  KEGKEYFKDLGKHKKDFIWVDDNDGEAIELAFSKKKIEARKNWLRQFEPGTYLDQKEKLI 677

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDF++KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAKVAQ SGYVSE
Sbjct: 678  KYSDFINKELILFSLADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSE 737

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+ I+GMAQD++GSNNINLLQPNGQFGTR+QGGKDHASARY+YT LSPI
Sbjct: 738  HSAYHHGEQSLASAIIGMAQDFVGSNNINLLQPNGQFGTRNQGGKDHASARYVYTRLSPI 797

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TR LF K+DD LL YLNEDGQS+EPTWY+P+IPMVLVNG+EGIGTGWS+YIPNYNPRDI+
Sbjct: 798  TRSLFPKDDDILLDYLNEDGQSIEPTWYMPIIPMVLVNGSEGIGTGWSSYIPNYNPRDII 857

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
             N+R  LN+EPMEPM PWYKGF+GTIE T TK+AG SY V GI+EEV++TT+R+TELPVR
Sbjct: 858  GNIRRLLNNEPMEPMEPWYKGFRGTIEKTATKEAGASYTVSGIVEEVDETTIRVTELPVR 917

Query: 1079 KSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKF 1258
            K T++YK+FL+ ++    + K+ FIK+FR+  DD TV+ +I MSE+NL MAK+EGL++KF
Sbjct: 918  KWTQDYKEFLESIMMGNEKVKDPFIKEFRDHTDDTTVYLDIIMSEENLLMAKQEGLLKKF 977

Query: 1259 KLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXX 1438
            KL+TTISTSNMHLF+ +G++ K+ +PE+I+EEF  LRLEFYEKRK  +L           
Sbjct: 978  KLTTTISTSNMHLFDSQGIIKKFDNPEQILEEFFHLRLEFYEKRKKVLLDNLQLELLKLD 1037

Query: 1439 NKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPR-------------------NAX 1561
            NKVRFI  V++G II+ NRKR+DL  ELK+K FTPFP+                    + 
Sbjct: 1038 NKVRFILAVVEGSIIVSNRKRADLFLELKEKGFTPFPKKKSVEAAVAGSIEDAEETEESS 1097

Query: 1562 XXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLD 1741
                        YEYL+SM IG+LT+EKVQELCA R KL  EVD L  ATPKSLW KDLD
Sbjct: 1098 EVATSKGVRASDYEYLISMAIGSLTLEKVQELCADRDKLKGEVDDLIKATPKSLWTKDLD 1157

Query: 1742 SLEQKLNLQSKIYD------MPEKRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEK 1903
            +LE +L+ Q  I D        E R +   +   +P R   K      KKA+N +   E 
Sbjct: 1158 ALESQLDEQD-ISDAQAEAARKEMRSKAMKDDGPKPTRQAPKNPRKYNKKASNTEPTTEP 1216

Query: 1904 HTVPSDC---TGKVPEAVELEGITTGRDEISTPNPPSLDVNEDRGLEQKEE--------- 2047
              + S     T  V E  + +G   G  +       +  V  D   E  +E         
Sbjct: 1217 MEISSSSALETNNVVEVAKPKG-KAGPKKAPARKGKTFSVLRDEDDEDDDEVLALKDRLA 1275

Query: 2048 -QPKQSSSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETV 2224
                 SSSPD S   +    ++P  + ++R +       + EISD + D           
Sbjct: 1276 AYNLGSSSPDQSETME---TEIPKREPSKRATTKKPLVSVTEISDDDDD----------Q 1322

Query: 2225 IEISDSE 2245
            IEISD E
Sbjct: 1323 IEISDDE 1329


>ref|XP_010023597.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus grandis]
 gb|KCW59909.1| hypothetical protein EUGRSUZ_H02633 [Eucalyptus grandis]
          Length = 1438

 Score =  846 bits (2185), Expect = 0.0
 Identities = 446/786 (56%), Positives = 561/786 (71%), Gaps = 38/786 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT + G+ LSFY++PEYE+WK+SL GN SGWSIKYYKGLGTSTS
Sbjct: 567  LKVPSFLVEFITPIVKATHKNGRELSFYTMPEYESWKESLGGNASGWSIKYYKGLGTSTS 626

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK+YFQ+L+ HKKDF+W+D +D DAIELAFSK KI+ARK WL++YEPGTYLDQKEK I
Sbjct: 627  KEGKQYFQNLQLHKKDFVWVDDQDGDAIELAFSKKKIEARKTWLRQYEPGTYLDQKEKLI 686

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDFV+KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNFIKEAKVAQ SGYVSE
Sbjct: 687  KYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSE 746

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTR+ GGKDHAS+RYIYT LSPI
Sbjct: 747  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLMPNGQFGTRNLGGKDHASSRYIYTKLSPI 806

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL+YLNEDGQS+EPTWY+P++P VLVNG+EGIGTGWS+YIPNYNPRDI+
Sbjct: 807  TRFLFPKDDDNLLNYLNEDGQSIEPTWYMPILPTVLVNGSEGIGTGWSSYIPNYNPRDII 866

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GF+GTIE T TK+AG SY V GI+EEV+ TT+RITELP+R
Sbjct: 867  ANLRRLLNGEMMEPMDPWYRGFRGTIEKTATKEAGVSYTVCGIVEEVDDTTLRITELPIR 926

Query: 1079 KSTEEYKQFLDKLISKGGRNK--EQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIE 1252
            + T++Y++FL+ L S G R+K  + F+K+FR+++DD TVHFE+ ++E+N+ +AK+EGL++
Sbjct: 927  RWTQDYREFLESL-STGERDKTKDPFVKEFRQYSDDVTVHFEVMLTEENMMIAKQEGLLK 985

Query: 1253 KFKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXX 1432
            KFKL++TISTSNMHLF+  GV+ KY SPE+I+EEF  LRLE YEKRK  +L         
Sbjct: 986  KFKLTSTISTSNMHLFDSNGVIKKYDSPEQILEEFFHLRLECYEKRKKILLENLELKLVM 1045

Query: 1433 XXNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNAXXXXXXXXXXXXX----- 1597
              NKVRFI  V+ G+II+ NRKR+DL  EL+ K F PF +                    
Sbjct: 1046 LDNKVRFILGVVHGEIIVSNRKRADLFQELQAKGFAPFRKETKTIETGVAGSTDDSEEIE 1105

Query: 1598 -------------YEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         YEYLLSM IGTLT+EKVQELCA + KL  EVD LR ATP++LWLKDL
Sbjct: 1106 ENSGATKGVRASDYEYLLSMAIGTLTLEKVQELCADKDKLVNEVDDLRKATPENLWLKDL 1165

Query: 1739 DSLEQKLNLQSKIYDMPEKRLEVNAE---ISKRPKRTMRKKQESSEKKANNKDGLAEKHT 1909
             +LE+KL+ Q KI    E+  +  ++   +  +  R   KK   +  KA N +  AE   
Sbjct: 1166 AALEEKLDEQEKIDAQAEETRKARSKTNGVGTKVSRQAPKKPRQNNSKAKNSEAQAE--- 1222

Query: 1910 VPSDCTGKVPEAVELEGIT--------TGRDEISTPNP-PSLDVNEDRGLEQKEEQPKQS 2062
                 T     A+E E +          G  +   P P  S  V++D   E  + + + +
Sbjct: 1223 ----VTRGSTVALEAENVADVVKPKRGAGAKKAPAPKPRKSASVSDDEDFELLDLRERLA 1278

Query: 2063 -----SSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVI 2227
                 SSPD S   +  V ++P +       A +     + +SDT  + EN   + +   
Sbjct: 1279 AYNLESSPDNSSALEDKVPEIPVKAKEPSKRAASKKKASVILSDTSEE-ENSNDSGDNDD 1337

Query: 2228 EISDSE 2245
            E+ DSE
Sbjct: 1338 EVVDSE 1343


>ref|XP_020703085.1| DNA topoisomerase 2-like [Dendrobium catenatum]
 gb|PKU64218.1| DNA topoisomerase 2 [Dendrobium catenatum]
          Length = 1268

 Score =  840 bits (2170), Expect = 0.0
 Identities = 434/765 (56%), Positives = 549/765 (71%), Gaps = 30/765 (3%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LKIP+FL+EFITPI+KAT R G+VLSFY++PEYE+WK+SL GN SGWSIKYYKGLGTSTS
Sbjct: 365  LKIPSFLVEFITPIVKATYRTGKVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTS 424

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGKEYFQDL+KHKKDF+W D++D +AIELAFSK KI+ARK WL+++EPGTYLDQ EK I
Sbjct: 425  KEGKEYFQDLQKHKKDFVWFDEQDGEAIELAFSKKKIEARKNWLRQFEPGTYLDQNEKLI 484

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
             YSDFV+KELI FS+ADL+RSIPSM+DG KPGQRKILF  FKRNF+KEAK++Q SGYVSE
Sbjct: 485  SYSDFVNKELILFSMADLQRSIPSMLDGLKPGQRKILFCSFKRNFVKEAKISQFSGYVSE 544

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLLQPNGQFGTRHQGGKDHASARYIYT LSP+
Sbjct: 545  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTKLSPM 604

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K DD +L Y++EDGQS+EP WYVP+IPMVLVNG+EGIGTGWS+YIPNYNPRDIV
Sbjct: 605  TRFLFPKEDDLILDYMSEDGQSIEPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIV 664

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
             NVR  LNDEPM PM PWY+GFKG IE T  K+AG +Y V GIIEE +  T+ ITELPVR
Sbjct: 665  KNVRRLLNDEPMLPMDPWYRGFKGLIEKTAVKEAGATYTVTGIIEESDSNTLTITELPVR 724

Query: 1079 KSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKF 1258
            + T++YK+FL+ L++   + K+ FIKD+RE+NDD TVHFE+ +SE+NL MAK+EGL +KF
Sbjct: 725  RWTQDYKEFLESLVTGTDKVKDPFIKDYREYNDDTTVHFEVTLSEQNLIMAKQEGLEKKF 784

Query: 1259 KLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXX 1438
            KLSTTISTSNMHLF+ KGV+ KY +PE+I+EEF  LR+ +YEKRK  +L           
Sbjct: 785  KLSTTISTSNMHLFDHKGVIKKYDTPEQILEEFFHLRITYYEKRKKALLDNLELDLLKLD 844

Query: 1439 NKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNA-------------------X 1561
            NKVRFI  V++G+II+ NRKR++L  EL++K FTPFP+                      
Sbjct: 845  NKVRFILGVVKGQIIVNNRKRAELFLELQEKGFTPFPKKTKGVDVAIAGATPETEESEET 904

Query: 1562 XXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLD 1741
                        Y+YLLSM IGTLT EKVQELCA+++K   +V  LR +TP SLW+KDLD
Sbjct: 905  TEVAKGGVKPSDYDYLLSMAIGTLTWEKVQELCAEKEKFENDVKELRGSTPSSLWIKDLD 964

Query: 1742 SLEQKL-NLQSKIYDMPEKRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPS 1918
            +L+++L NL+ +  +    R ++ A+         ++  +   K         E   + S
Sbjct: 965  ALDKELDNLERQDAEAEVMRKKIKAKAGNGGAAAAKQAPKKPRKNNTKPSAATEPIAIDS 1024

Query: 1919 DCTGKVPEAVELEGITTGRDEISTPNPPSLDVNEDR---GLEQKEEQPKQSSSP-----D 2074
            +   +V      +    GR   S   P S++ +ED     L+++ E     SSP     +
Sbjct: 1025 ETVQEV-----TKNKPKGRQNKSKSQPVSVESDEDEDLIALKERLEAYNLDSSPERLAME 1079

Query: 2075 TSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDT-EVDCENKQ 2206
            T   P+ +  +  P+   +R +A      ++   DT + D EN +
Sbjct: 1080 TETMPEAAAAKEGPK---KRAAAARKAMTVVSDEDTDDEDFENSK 1121


>ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus grandis]
 gb|KCW60013.1| hypothetical protein EUGRSUZ_H02748 [Eucalyptus grandis]
          Length = 1496

 Score =  843 bits (2178), Expect = 0.0
 Identities = 439/781 (56%), Positives = 559/781 (71%), Gaps = 33/781 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT + G+ LSFY++PEYE+WK+SL G+ SGWSIKYYKGLGTSTS
Sbjct: 574  LKVPSFLVEFITPIVKATHKNGRELSFYTMPEYESWKESLGGSGSGWSIKYYKGLGTSTS 633

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK+YFQ+L+ HKKDF+W+D +D DAIELAFSK KI+ARK WL+++EPGTYLDQKEK I
Sbjct: 634  KEGKQYFQNLDMHKKDFVWVDDQDGDAIELAFSKKKIEARKTWLRQFEPGTYLDQKEKLI 693

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDFV+KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNFIKEAKVAQ SGYVSE
Sbjct: 694  KYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSE 753

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQDY+GSNNINLL PNGQFGTR+ GGKDHAS RY+YT LSP 
Sbjct: 754  HSAYHHGEQSLASTIIGMAQDYVGSNNINLLMPNGQFGTRNMGGKDHASPRYVYTKLSPT 813

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YLNEDGQS+EPTWY+P++PMVLVNG+EGIGTGWS+YIPNYNPRDI+
Sbjct: 814  TRFLFPKDDDNLLSYLNEDGQSIEPTWYMPILPMVLVNGSEGIGTGWSSYIPNYNPRDII 873

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GF+GTIE T TK+AG +Y V GIIEEV+ TT+RITELP+R
Sbjct: 874  ANLRRLLNGEMMEPMDPWYRGFRGTIEKTATKEAGVTYTVCGIIEEVDDTTLRITELPIR 933

Query: 1079 KSTEEYKQFLDKLIS-KGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEK 1255
            + T++Y++FL+ L + +  + K+ F+K+FR+++DD TVHFE+ ++E+N+ +AK+EGL++K
Sbjct: 934  RWTQDYREFLESLSTGEKDKAKDPFVKEFRQYSDDVTVHFEVMLTEENMMIAKQEGLLKK 993

Query: 1256 FKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXX 1435
            FKL+++ISTSNMHLF+P GV+ KY SPE+I+EEF  LRLE YEKRK  +L          
Sbjct: 994  FKLTSSISTSNMHLFDPNGVIKKYDSPEQILEEFFHLRLECYEKRKKILLENLELKLVML 1053

Query: 1436 XNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNAXXXXXXXXXXXXX------ 1597
             NKVRFI  V+ G+II+ NRKR+DL  EL+ K FTPF +                     
Sbjct: 1054 DNKVRFILGVVHGEIIVSNRKRADLFQELQAKGFTPFRKETKTIETAVAGSTDDAEETEE 1113

Query: 1598 -------------YEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         YEYLLSM IG LT+EKVQELCA + KL  EVD LR ATP++LWL+DL
Sbjct: 1114 NSEPTTKGVKASDYEYLLSMAIGALTLEKVQELCADKDKLVDEVDALRKATPENLWLEDL 1173

Query: 1739 DSLEQKLNLQSKIYDMPEKRLEVNAE---ISKRPKRTMRKKQESSEKKANNKDGLAEKHT 1909
             +LE+KL+ Q K+    E+  +  ++   +  +  R   KK   ++ KANN +  AE  T
Sbjct: 1174 AALEEKLDEQEKMDAQAEETRKARSKANGVGTKVSRQAPKKPRKNDTKANNPEAQAEV-T 1232

Query: 1910 VPSDCTGKVPEAVELEGITTGRDEISTPNP---PSLDVNED------RGLEQKEEQPKQS 2062
              S  T +   A ++     G      P P    S  V++D        L+++       
Sbjct: 1233 QGSTVTLEAGNAADVAKPKRGAGARKAPAPKPSKSASVSDDDEDFEMLDLKERLAAYNLE 1292

Query: 2063 SSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETVIEISDS 2242
            SSPD S   +  V ++P ++      A     P + +S+   + EN   + +   E  DS
Sbjct: 1293 SSPDNSSALEDKVPEIPVKEKEPSKRAATRKKPSVILSEISEE-ENSNDSGDDDYETVDS 1351

Query: 2243 E 2245
            E
Sbjct: 1352 E 1352


>ref|XP_011013333.1| PREDICTED: DNA topoisomerase 2-like isoform X4 [Populus euphratica]
          Length = 1463

 Score =  839 bits (2168), Expect = 0.0
 Identities = 442/761 (58%), Positives = 550/761 (72%), Gaps = 33/761 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT R G VLSFYS+PEYE+WK SL GN SGWSIKYYKGLGTSTS
Sbjct: 557  LKVPSFLVEFITPIVKATHRNGTVLSFYSMPEYESWKGSLVGNASGWSIKYYKGLGTSTS 616

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK YFQ L+KHKKDF+W+D++D DAIELAFSK KI+ARK WL++YEPGT+LDQ +K I
Sbjct: 617  KEGKAYFQSLDKHKKDFIWMDEQDGDAIELAFSKKKIEARKNWLRQYEPGTHLDQNQKLI 676

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDF++KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAKV+Q SGYVSE
Sbjct: 677  KYSDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSE 736

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTR  GGKDHASARYIYT LSPI
Sbjct: 737  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRSVGGKDHASARYIYTQLSPI 796

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YL+EDGQ++EP WY+P+IP+VLVNG EGIGTGWST+IPNYNPRD+V
Sbjct: 797  TRFLFPKDDDGLLDYLDEDGQTIEPNWYMPIIPLVLVNGCEGIGTGWSTFIPNYNPRDVV 856

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GFKGTIE   +K+AG SY V G+I+EVN+TT+RITELP+R
Sbjct: 857  ANIRRLLNGEMMEPMNPWYRGFKGTIEKGASKEAGCSYAVNGVIDEVNETTLRITELPIR 916

Query: 1079 KSTEEYKQFLDKLISKGGRN------KEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEE 1240
            + T++YK FL+  +++G R+      K+ FIKDFR++ DD TV FE+ +SE+N+ +AK+E
Sbjct: 917  RWTDDYKAFLNS-VTEGNRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQE 975

Query: 1241 GLIEKFKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXX 1420
            GL++KFKL+TTISTSNMHLF+  GV+ KY +PE+I+EEF  LRLE+YE+RK  +L     
Sbjct: 976  GLLKKFKLTTTISTSNMHLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEF 1035

Query: 1421 XXXXXXNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NA 1558
                  NKVRFI  V++G+II+ NRKR+DL  EL QK FTP P+               A
Sbjct: 1036 ELLKLENKVRFILGVVRGEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAGATDDKDEA 1095

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         Y+YLLSM IGTLT+EKVQ+LCA   KLN EVD LR  TP  LW+KDL
Sbjct: 1096 EDSLEVSGVRASDYDYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDL 1155

Query: 1739 DSLEQKLNLQSKIYDM----PEKRL--EVNAEISKRPKRTMRKKQESSEKKANNKDGLAE 1900
            ++LE +L++  K YD       K+L  + N E   +  +   K      KKA N++   E
Sbjct: 1156 EALEMQLDVLDK-YDAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKYTKKAINEEVSVE 1214

Query: 1901 KHTVPSDCTGKVPEAVEL---EGITTGRDEISTPNPPSLDVNEDRGLEQKEEQPKQ---S 2062
                PS  T +   A E+   +G    R   +    PS   +ED  +E  +++ K     
Sbjct: 1215 TMGKPSSSTMETENAAEVVKPKGRAGSRKAPAKKEKPSPSSDEDDEIESLKDRLKAYRLD 1274

Query: 2063 SSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTE 2185
            SSP+ S + +  VL+VP   N  R       A +  ISD+E
Sbjct: 1275 SSPEQSADMETDVLRVPAGRNAARKKP---LAAVSVISDSE 1312


>ref|XP_011013332.1| PREDICTED: DNA topoisomerase 2-like isoform X3 [Populus euphratica]
          Length = 1464

 Score =  837 bits (2163), Expect = 0.0
 Identities = 441/762 (57%), Positives = 551/762 (72%), Gaps = 34/762 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT R G VLSFYS+PEYE+WK SL GN SGWSIKYYKGLGTSTS
Sbjct: 557  LKVPSFLVEFITPIVKATHRNGTVLSFYSMPEYESWKGSLVGNASGWSIKYYKGLGTSTS 616

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK YFQ L+KHKKDF+W+D++D DAIELAFSK KI+ARK WL++YEPGT+LDQ +K I
Sbjct: 617  KEGKAYFQSLDKHKKDFIWMDEQDGDAIELAFSKKKIEARKNWLRQYEPGTHLDQNQKLI 676

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDF++KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAKV+Q SGYVSE
Sbjct: 677  KYSDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSE 736

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTR  GGKDHASARYIYT LSPI
Sbjct: 737  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRSVGGKDHASARYIYTQLSPI 796

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YL+EDGQ++EP WY+P+IP+VLVNG EGIGTGWST+IPNYNPRD+V
Sbjct: 797  TRFLFPKDDDGLLDYLDEDGQTIEPNWYMPIIPLVLVNGCEGIGTGWSTFIPNYNPRDVV 856

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GFKGTIE   +K+AG SY V G+I+EVN+TT+RITELP+R
Sbjct: 857  ANIRRLLNGEMMEPMNPWYRGFKGTIEKGASKEAGCSYAVNGVIDEVNETTLRITELPIR 916

Query: 1079 KSTEEYKQFLDKLISKGGRN------KEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEE 1240
            + T++YK FL+  +++G R+      K+ FIKDFR++ DD TV FE+ +SE+N+ +AK+E
Sbjct: 917  RWTDDYKAFLNS-VTEGNRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQE 975

Query: 1241 GLIEKFKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXX 1420
            GL++KFKL+TTISTSNMHLF+  GV+ KY +PE+I+EEF  LRLE+YE+RK  +L     
Sbjct: 976  GLLKKFKLTTTISTSNMHLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEF 1035

Query: 1421 XXXXXXNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NA 1558
                  NKVRFI  V++G+II+ NRKR+DL  EL QK FTP P+               A
Sbjct: 1036 ELLKLENKVRFILGVVRGEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAGATDDKDEA 1095

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         Y+YLLSM IGTLT+EKVQ+LCA   KLN EVD LR  TP  LW+KDL
Sbjct: 1096 EDSLEVSGVRASDYDYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDL 1155

Query: 1739 DSLEQKLNLQSKIYDM----PEKRL--EVNAEISKRPKRTMRKKQESSEKKANNKDGLAE 1900
            ++LE +L++  K YD       K+L  + N E   +  +   K      KKA N++   E
Sbjct: 1156 EALEMQLDVLDK-YDAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKYTKKAINEEVSVE 1214

Query: 1901 KHTVPSDCTGKVPEAVEL---EGITTGR----DEISTPNPPSLDVNEDRGLEQKEEQPKQ 2059
                PS  T +   A E+   +G    R     +   P+P S + +E   L+ + +  + 
Sbjct: 1215 TMGKPSSSTMETENAAEVVKPKGRAGSRKAPAKKQEKPSPSSDEDDEIESLKDRLKAYRL 1274

Query: 2060 SSSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTE 2185
             SSP+ S + +  VL+VP   N  R       A +  ISD+E
Sbjct: 1275 DSSPEQSADMETDVLRVPAGRNAARKKP---LAAVSVISDSE 1313


>gb|PNT56778.1| hypothetical protein POPTR_001G264000v3 [Populus trichocarpa]
          Length = 1464

 Score =  837 bits (2161), Expect = 0.0
 Identities = 441/758 (58%), Positives = 547/758 (72%), Gaps = 30/758 (3%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT R G VLSFYS+PEYE+WK SL GN SGWSIKYYKGLGTSTS
Sbjct: 557  LKVPSFLVEFITPIVKATHRNGTVLSFYSMPEYESWKGSLAGNASGWSIKYYKGLGTSTS 616

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK YFQ L+KHKKDF+W+D++D DAIELAFSK KI+ARK WL++YEPGT+LDQ +K I
Sbjct: 617  KEGKAYFQSLDKHKKDFIWMDEQDGDAIELAFSKKKIEARKNWLRQYEPGTHLDQNQKLI 676

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDF++KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAK++Q SGYVSE
Sbjct: 677  KYSDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKISQFSGYVSE 736

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTR  GGKDHASARYIYT LSPI
Sbjct: 737  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRSVGGKDHASARYIYTQLSPI 796

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YL+EDGQ++EP WY+P+IPMVLVNG EGIGTGWST+IPNYNPRDIV
Sbjct: 797  TRFLFPKDDDGLLDYLDEDGQTIEPNWYMPIIPMVLVNGCEGIGTGWSTFIPNYNPRDIV 856

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GFKGTIE   +K+AG SY V G+I EVN+TT+RITELP+R
Sbjct: 857  ANIRRLLNGEMMEPMNPWYRGFKGTIEKGASKEAGCSYTVNGVINEVNETTLRITELPIR 916

Query: 1079 KSTEEYKQFLDKLISKGGRN------KEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEE 1240
            + T++YK FL+  +++G R+      K+ FIKDFR++ DD TV FE+ +SE+N+ +AK+E
Sbjct: 917  RWTDDYKAFLNS-VTEGNRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQE 975

Query: 1241 GLIEKFKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXX 1420
            GL++KFKL+TTISTSNMHLF+  GV+ KY +PE+I+EEF  LRLE+YE+RK  +L     
Sbjct: 976  GLLKKFKLTTTISTSNMHLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEF 1035

Query: 1421 XXXXXXNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NA 1558
                  NKVRFI  V++G+II+ NRKR+DL  EL QK FTP P+               A
Sbjct: 1036 ELLKLENKVRFILGVVRGEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAGATDDKDEA 1095

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         Y+YLLSM IGTLT+EKVQ+LCA   KLN EVD LR  TP  LW+KDL
Sbjct: 1096 EDSLEVSGVRASDYDYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDL 1155

Query: 1739 DSLEQKLNLQSKIYDM----PEKRL--EVNAEISKRPKRTMRKKQESSEKKANNKDGLAE 1900
            ++LE +L++  K YD       K+L  + N E   +  +   K      KKA N++   E
Sbjct: 1156 EALEMQLDVLDK-YDAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKYTKKAINEEVSVE 1214

Query: 1901 KHTVPSDCTGKVPEAVELEGITTGRDEISTPNPPSLDVNEDRGLEQKEEQPKQ---SSSP 2071
                    +    E V+ +G    R   +    PS   +ED  +E  +++ K     SSP
Sbjct: 1215 ---TMGKASSSAMETVKPKGRAGSRKAPAKKEKPSPISDEDDEIESLKDRLKAYRLDSSP 1271

Query: 2072 DTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTE 2185
            + S + +  VL+VP   N  RN      A +  ISD+E
Sbjct: 1272 EQSADMETEVLRVPAGRNAARNKP---LAAVSVISDSE 1306


>ref|XP_011013331.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Populus euphratica]
          Length = 1467

 Score =  837 bits (2161), Expect = 0.0
 Identities = 442/765 (57%), Positives = 549/765 (71%), Gaps = 37/765 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT R G VLSFYS+PEYE+WK SL GN SGWSIKYYKGLGTSTS
Sbjct: 557  LKVPSFLVEFITPIVKATHRNGTVLSFYSMPEYESWKGSLVGNASGWSIKYYKGLGTSTS 616

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK YFQ L+KHKKDF+W+D++D DAIELAFSK KI+ARK WL++YEPGT+LDQ +K I
Sbjct: 617  KEGKAYFQSLDKHKKDFIWMDEQDGDAIELAFSKKKIEARKNWLRQYEPGTHLDQNQKLI 676

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDF++KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAKV+Q SGYVSE
Sbjct: 677  KYSDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSE 736

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTR  GGKDHASARYIYT LSPI
Sbjct: 737  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRSVGGKDHASARYIYTQLSPI 796

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YL+EDGQ++EP WY+P+IP+VLVNG EGIGTGWST+IPNYNPRD+V
Sbjct: 797  TRFLFPKDDDGLLDYLDEDGQTIEPNWYMPIIPLVLVNGCEGIGTGWSTFIPNYNPRDVV 856

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GFKGTIE   +K+AG SY V G+I+EVN+TT+RITELP+R
Sbjct: 857  ANIRRLLNGEMMEPMNPWYRGFKGTIEKGASKEAGCSYAVNGVIDEVNETTLRITELPIR 916

Query: 1079 KSTEEYKQFLDKLISKGGRN------KEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEE 1240
            + T++YK FL+  +++G R+      K+ FIKDFR++ DD TV FE+ +SE+N+ +AK+E
Sbjct: 917  RWTDDYKAFLNS-VTEGNRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQE 975

Query: 1241 GLIEKFKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXX 1420
            GL++KFKL+TTISTSNMHLF+  GV+ KY +PE+I+EEF  LRLE+YE+RK  +L     
Sbjct: 976  GLLKKFKLTTTISTSNMHLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEF 1035

Query: 1421 XXXXXXNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NA 1558
                  NKVRFI  V++G+II+ NRKR+DL  EL QK FTP P+               A
Sbjct: 1036 ELLKLENKVRFILGVVRGEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAGATDDKDEA 1095

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         Y+YLLSM IGTLT+EKVQ+LCA   KLN EVD LR  TP  LW+KDL
Sbjct: 1096 EDSLEVSGVRASDYDYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDL 1155

Query: 1739 DSLEQKLNLQSKIYDM----PEKRL--EVNAEISKRPKRTMRKKQESSEKKANNKDGLAE 1900
            ++LE +L++  K YD       K+L  + N E   +  +   K      KKA N++   E
Sbjct: 1156 EALEMQLDVLDK-YDAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKYTKKAINEEVSVE 1214

Query: 1901 KHTVPSDCT-------GKVPEAVELEGITTGRDEISTPNPPSLDVNEDRGLEQKEEQPKQ 2059
                PS  T           E V+ +G    R   +    PS   +ED  +E  +++ K 
Sbjct: 1215 TMGKPSSSTMETGQQAENAAEVVKPKGRAGSRKAPAKKEKPSPSSDEDDEIESLKDRLKA 1274

Query: 2060 ---SSSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTE 2185
                SSP+ S + +  VL+VP   N  R       A +  ISD+E
Sbjct: 1275 YRLDSSPEQSADMETDVLRVPAGRNAARKKP---LAAVSVISDSE 1316


>gb|PNT56779.1| hypothetical protein POPTR_001G264000v3 [Populus trichocarpa]
          Length = 1465

 Score =  835 bits (2157), Expect = 0.0
 Identities = 440/759 (57%), Positives = 548/759 (72%), Gaps = 31/759 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT R G VLSFYS+PEYE+WK SL GN SGWSIKYYKGLGTSTS
Sbjct: 557  LKVPSFLVEFITPIVKATHRNGTVLSFYSMPEYESWKGSLAGNASGWSIKYYKGLGTSTS 616

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK YFQ L+KHKKDF+W+D++D DAIELAFSK KI+ARK WL++YEPGT+LDQ +K I
Sbjct: 617  KEGKAYFQSLDKHKKDFIWMDEQDGDAIELAFSKKKIEARKNWLRQYEPGTHLDQNQKLI 676

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDF++KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAK++Q SGYVSE
Sbjct: 677  KYSDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKISQFSGYVSE 736

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTR  GGKDHASARYIYT LSPI
Sbjct: 737  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRSVGGKDHASARYIYTQLSPI 796

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YL+EDGQ++EP WY+P+IPMVLVNG EGIGTGWST+IPNYNPRDIV
Sbjct: 797  TRFLFPKDDDGLLDYLDEDGQTIEPNWYMPIIPMVLVNGCEGIGTGWSTFIPNYNPRDIV 856

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GFKGTIE   +K+AG SY V G+I EVN+TT+RITELP+R
Sbjct: 857  ANIRRLLNGEMMEPMNPWYRGFKGTIEKGASKEAGCSYTVNGVINEVNETTLRITELPIR 916

Query: 1079 KSTEEYKQFLDKLISKGGRN------KEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEE 1240
            + T++YK FL+  +++G R+      K+ FIKDFR++ DD TV FE+ +SE+N+ +AK+E
Sbjct: 917  RWTDDYKAFLNS-VTEGNRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQE 975

Query: 1241 GLIEKFKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXX 1420
            GL++KFKL+TTISTSNMHLF+  GV+ KY +PE+I+EEF  LRLE+YE+RK  +L     
Sbjct: 976  GLLKKFKLTTTISTSNMHLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEF 1035

Query: 1421 XXXXXXNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NA 1558
                  NKVRFI  V++G+II+ NRKR+DL  EL QK FTP P+               A
Sbjct: 1036 ELLKLENKVRFILGVVRGEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAGATDDKDEA 1095

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         Y+YLLSM IGTLT+EKVQ+LCA   KLN EVD LR  TP  LW+KDL
Sbjct: 1096 EDSLEVSGVRASDYDYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDL 1155

Query: 1739 DSLEQKLNLQSKIYDM----PEKRL--EVNAEISKRPKRTMRKKQESSEKKANNKDGLAE 1900
            ++LE +L++  K YD       K+L  + N E   +  +   K      KKA N++   E
Sbjct: 1156 EALEMQLDVLDK-YDAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKYTKKAINEEVSVE 1214

Query: 1901 KHTVPSDCTGKVPEAVELEGITTGR----DEISTPNPPSLDVNEDRGLEQKEEQPKQSSS 2068
                    +    E V+ +G    R     +   P+P S + +E   L+ + +  +  SS
Sbjct: 1215 ---TMGKASSSAMETVKPKGRAGSRKAPAKKQEKPSPISDEDDEIESLKDRLKAYRLDSS 1271

Query: 2069 PDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTE 2185
            P+ S + +  VL+VP   N  RN      A +  ISD+E
Sbjct: 1272 PEQSADMETEVLRVPAGRNAARNKP---LAAVSVISDSE 1307


>ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Ziziphus jujuba]
          Length = 1486

 Score =  835 bits (2158), Expect = 0.0
 Identities = 452/800 (56%), Positives = 563/800 (70%), Gaps = 36/800 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT + G+ L+FY++P+YE+W++SL GN SGWSIKYYKGLGTSTS
Sbjct: 566  LKVPSFLVEFITPIVKATHKNGKELAFYTMPQYESWRESLRGNASGWSIKYYKGLGTSTS 625

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEG+EYFQ+L+KH+KDFLW+D +D  AIELAFSK KI+ RK WL+++EPGT+LDQKEK I
Sbjct: 626  KEGREYFQNLDKHRKDFLWVDDQDGAAIELAFSKKKIEERKNWLRQFEPGTHLDQKEKLI 685

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDFV KELI FSVADL+RSIPSMVDG KPGQRKILF  FKRNF KEAKVAQ SGYVSE
Sbjct: 686  KYSDFVHKELILFSVADLQRSIPSMVDGLKPGQRKILFCSFKRNFFKEAKVAQFSGYVSE 745

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQDY+GSNNINLLQPNGQFGTR+ GGKDHASARYI+T LSPI
Sbjct: 746  HSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPNGQFGTRNLGGKDHASARYIFTRLSPI 805

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YLNEDGQ++EPTWYVP+IP VLVNG+EGIGTGWS+YIPNYNPRDIV
Sbjct: 806  TRFLFPKDDDKLLDYLNEDGQTIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIV 865

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN   M PM PWY+GFKGTIE T  K+AG SY + GI+EEVN+TT+RITELP+R
Sbjct: 866  ANIRRLLNGHSMVPMDPWYRGFKGTIEKT-VKEAGVSYTISGILEEVNETTIRITELPIR 924

Query: 1079 KSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKF 1258
            K T++YK+FL+ +     + K+ FI+ F + +D  TV   ++M E+NL  AK+EGL++KF
Sbjct: 925  KWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHITVDILVHMPEENLVAAKQEGLLKKF 984

Query: 1259 KLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXX 1438
            KL+TTISTSNMHLF+ KGV+ KY +PE+I+EEF  LRLEFYEKRK  +L           
Sbjct: 985  KLTTTISTSNMHLFDAKGVIKKYDTPEQILEEFFHLRLEFYEKRKQVLLDNLEMELLKLE 1044

Query: 1439 NKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNA-----------------XXX 1567
            NKVRFI  V+  +II+ NRKR+DL  EL+QK FTPFP+ A                    
Sbjct: 1045 NKVRFILGVVNEEIIVSNRKRADLFLELQQKGFTPFPKKAKSVEPEVAGATDYTEETEDN 1104

Query: 1568 XXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSL 1747
                      YEYLLSM IGTLT+EKVQ LCA+R KLN EVD LR ATPKSLW KDLD+L
Sbjct: 1105 SNPDGVRISDYEYLLSMAIGTLTLEKVQALCAERDKLNGEVDDLRKATPKSLWEKDLDAL 1164

Query: 1748 EQKLNLQSKIYDMPE---KRLEVN---AEISKRPKRTMRKKQESSEKKANNKDGLAEKHT 1909
            +++L+   K     E   K+L+     A ++K  K    K    + KKANN + + E   
Sbjct: 1165 DKELDELDKNDAQAEDARKKLKSQLNPAAVTKFAKAP--KNPRKNNKKANNAEAVVEMME 1222

Query: 1910 VPSDCT---GKVPEAVELEGITTGRDEISTPNPPSL----DVNEDRGLEQKEEQPKQS-- 2062
              S  T    K PE V+ +G    R   +    P++    D ++D  LE KE     +  
Sbjct: 1223 TTSSSTMEMEKAPEVVKPKGRAVSRKAPTKKEKPAVILDDDDDDDEVLELKERLAAYNLE 1282

Query: 2063 SSPDTSREPKMSVLQVP--PEDNTRRNSAD-NLNAPIIEISDTEVDCENKQQTAETVIEI 2233
            SSPD   + +    QVP   ++ T+R +A    +  +  ISD E +  ++    ET  E 
Sbjct: 1283 SSPDRPADMESEAPQVPVQKKEPTKRAAAQKKASVNLTTISDDEDESFDEDFELET--EA 1340

Query: 2234 SDSEVVCEDEVPNTRINNPS 2293
            +  +        NT+ + P+
Sbjct: 1341 AAKKKGGRKAAANTKASKPN 1360


>ref|XP_011013328.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Populus euphratica]
 ref|XP_011013329.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Populus euphratica]
 ref|XP_011013330.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Populus euphratica]
          Length = 1468

 Score =  835 bits (2156), Expect = 0.0
 Identities = 441/766 (57%), Positives = 550/766 (71%), Gaps = 38/766 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT R G VLSFYS+PEYE+WK SL GN SGWSIKYYKGLGTSTS
Sbjct: 557  LKVPSFLVEFITPIVKATHRNGTVLSFYSMPEYESWKGSLVGNASGWSIKYYKGLGTSTS 616

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK YFQ L+KHKKDF+W+D++D DAIELAFSK KI+ARK WL++YEPGT+LDQ +K I
Sbjct: 617  KEGKAYFQSLDKHKKDFIWMDEQDGDAIELAFSKKKIEARKNWLRQYEPGTHLDQNQKLI 676

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDF++KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAKV+Q SGYVSE
Sbjct: 677  KYSDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSE 736

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTR  GGKDHASARYIYT LSPI
Sbjct: 737  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRSVGGKDHASARYIYTQLSPI 796

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YL+EDGQ++EP WY+P+IP+VLVNG EGIGTGWST+IPNYNPRD+V
Sbjct: 797  TRFLFPKDDDGLLDYLDEDGQTIEPNWYMPIIPLVLVNGCEGIGTGWSTFIPNYNPRDVV 856

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GFKGTIE   +K+AG SY V G+I+EVN+TT+RITELP+R
Sbjct: 857  ANIRRLLNGEMMEPMNPWYRGFKGTIEKGASKEAGCSYAVNGVIDEVNETTLRITELPIR 916

Query: 1079 KSTEEYKQFLDKLISKGGRN------KEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEE 1240
            + T++YK FL+  +++G R+      K+ FIKDFR++ DD TV FE+ +SE+N+ +AK+E
Sbjct: 917  RWTDDYKAFLNS-VTEGNRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQE 975

Query: 1241 GLIEKFKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXX 1420
            GL++KFKL+TTISTSNMHLF+  GV+ KY +PE+I+EEF  LRLE+YE+RK  +L     
Sbjct: 976  GLLKKFKLTTTISTSNMHLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEF 1035

Query: 1421 XXXXXXNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NA 1558
                  NKVRFI  V++G+II+ NRKR+DL  EL QK FTP P+               A
Sbjct: 1036 ELLKLENKVRFILGVVRGEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAGATDDKDEA 1095

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         Y+YLLSM IGTLT+EKVQ+LCA   KLN EVD LR  TP  LW+KDL
Sbjct: 1096 EDSLEVSGVRASDYDYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDL 1155

Query: 1739 DSLEQKLNLQSKIYDM----PEKRL--EVNAEISKRPKRTMRKKQESSEKKANNKDGLAE 1900
            ++LE +L++  K YD       K+L  + N E   +  +   K      KKA N++   E
Sbjct: 1156 EALEMQLDVLDK-YDAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKYTKKAINEEVSVE 1214

Query: 1901 KHTVPSDCT-------GKVPEAVELEGITTGR----DEISTPNPPSLDVNEDRGLEQKEE 2047
                PS  T           E V+ +G    R     +   P+P S + +E   L+ + +
Sbjct: 1215 TMGKPSSSTMETGQQAENAAEVVKPKGRAGSRKAPAKKQEKPSPSSDEDDEIESLKDRLK 1274

Query: 2048 QPKQSSSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTE 2185
              +  SSP+ S + +  VL+VP   N  R       A +  ISD+E
Sbjct: 1275 AYRLDSSPEQSADMETDVLRVPAGRNAARKKP---LAAVSVISDSE 1317


>ref|XP_015881653.1| PREDICTED: DNA topoisomerase 2 isoform X1 [Ziziphus jujuba]
          Length = 1487

 Score =  831 bits (2147), Expect = 0.0
 Identities = 452/801 (56%), Positives = 562/801 (70%), Gaps = 37/801 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT + G+ L+FY++P+YE+W++SL GN SGWSIKYYKGLGTSTS
Sbjct: 566  LKVPSFLVEFITPIVKATHKNGKELAFYTMPQYESWRESLRGNASGWSIKYYKGLGTSTS 625

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEG+EYFQ+L+KH+KDFLW+D +D  AIELAFSK KI+ RK WL+++EPGT+LDQKEK I
Sbjct: 626  KEGREYFQNLDKHRKDFLWVDDQDGAAIELAFSKKKIEERKNWLRQFEPGTHLDQKEKLI 685

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDFV KELI FSVADL+RSIPSMVDG KPGQRKILF  FKRNF KEAKVAQ SGYVSE
Sbjct: 686  KYSDFVHKELILFSVADLQRSIPSMVDGLKPGQRKILFCSFKRNFFKEAKVAQFSGYVSE 745

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQDY+GSNNINLLQPNGQFGTR+ GGKDHASARYI+T LSPI
Sbjct: 746  HSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPNGQFGTRNLGGKDHASARYIFTRLSPI 805

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YLNEDGQ++EPTWYVP+IP VLVNG+EGIGTGWS+YIPNYNPRDIV
Sbjct: 806  TRFLFPKDDDKLLDYLNEDGQTIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIV 865

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN   M PM PWY+GFKGTIE T  K+AG SY + GI+EEVN+TT+RITELP+R
Sbjct: 866  ANIRRLLNGHSMVPMDPWYRGFKGTIEKT-VKEAGVSYTISGILEEVNETTIRITELPIR 924

Query: 1079 KSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKF 1258
            K T++YK+FL+ +     + K+ FI+ F + +D  TV   ++M E+NL  AK+EGL++KF
Sbjct: 925  KWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHITVDILVHMPEENLVAAKQEGLLKKF 984

Query: 1259 KLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXX 1438
            KL+TTISTSNMHLF+ KGV+ KY +PE+I+EEF  LRLEFYEKRK  +L           
Sbjct: 985  KLTTTISTSNMHLFDAKGVIKKYDTPEQILEEFFHLRLEFYEKRKQVLLDNLEMELLKLE 1044

Query: 1439 NKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNA-----------------XXX 1567
            NKVRFI  V+  +II+ NRKR+DL  EL+QK FTPFP+ A                    
Sbjct: 1045 NKVRFILGVVNEEIIVSNRKRADLFLELQQKGFTPFPKKAKSVEPEVAGATDYTEETEDN 1104

Query: 1568 XXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDSL 1747
                      YEYLLSM IGTLT+EKVQ LCA+R KLN EVD LR ATPKSLW KDLD+L
Sbjct: 1105 SNPDGVRISDYEYLLSMAIGTLTLEKVQALCAERDKLNGEVDDLRKATPKSLWEKDLDAL 1164

Query: 1748 EQKLNLQSKIYDMPE---KRLEVN---AEISKRPKRTMRKKQESSEKKANNKDGLAEKHT 1909
            +++L+   K     E   K+L+     A ++K  K    K    + KKANN + + E   
Sbjct: 1165 DKELDELDKNDAQAEDARKKLKSQLNPAAVTKFAKAP--KNPRKNNKKANNAEAVVEMME 1222

Query: 1910 VPSDCT---GKVPEAVELEGITTGRD-EISTPNPPSL----DVNEDRGLEQKEEQPKQS- 2062
              S  T    K PE V+ +G    R         P++    D ++D  LE KE     + 
Sbjct: 1223 TTSSSTMEMEKAPEVVKPKGRAVSRKAPTKKQEKPAVILDDDDDDDEVLELKERLAAYNL 1282

Query: 2063 -SSPDTSREPKMSVLQVP--PEDNTRRNSAD-NLNAPIIEISDTEVDCENKQQTAETVIE 2230
             SSPD   + +    QVP   ++ T+R +A    +  +  ISD E +  ++    ET  E
Sbjct: 1283 ESSPDRPADMESEAPQVPVQKKEPTKRAAAQKKASVNLTTISDDEDESFDEDFELET--E 1340

Query: 2231 ISDSEVVCEDEVPNTRINNPS 2293
             +  +        NT+ + P+
Sbjct: 1341 AAAKKKGGRKAAANTKASKPN 1361


>ref|XP_002298421.2| DNA topoisomerase family protein [Populus trichocarpa]
          Length = 1485

 Score =  831 bits (2146), Expect = 0.0
 Identities = 440/762 (57%), Positives = 551/762 (72%), Gaps = 34/762 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT R G VLSFYS+PEYE+WK SL GN SGWSIKYYKGLGTSTS
Sbjct: 571  LKVPSFLVEFITPIVKATHRNGTVLSFYSMPEYESWKGSLAGNASGWSIKYYKGLGTSTS 630

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK YFQ L+KHKKDF+W+D++D DAIELAFSK KI+ARK WL++YEPGT+LDQ +K I
Sbjct: 631  KEGKAYFQSLDKHKKDFIWMDEQDGDAIELAFSKKKIEARKNWLRQYEPGTHLDQNQKLI 690

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDF++KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAK++Q SGYVSE
Sbjct: 691  KYSDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKISQFSGYVSE 750

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA+TI+GMAQD++GSNNINLL PNGQFGTR  GGKDHASARYIYT LSPI
Sbjct: 751  HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRSVGGKDHASARYIYTQLSPI 810

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL YL+EDGQ++EP WY+P+IPMVLVNG EGIGTGWST+IPNYNPRDIV
Sbjct: 811  TRFLFPKDDDGLLDYLDEDGQTIEPNWYMPIIPMVLVNGCEGIGTGWSTFIPNYNPRDIV 870

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GFKGTIE   +K+AG SY V G+I EVN+TT+RITELP+R
Sbjct: 871  ANIRRLLNGEMMEPMNPWYRGFKGTIEKGASKEAGCSYTVNGVINEVNETTLRITELPIR 930

Query: 1079 KSTEEYKQFLDKLISKGGRN------KEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEE 1240
            + T++YK FL+  +++G R+      K+ FIKDFR++ DD TV FE+ +SE+N+ +AK+E
Sbjct: 931  RWTDDYKAFLNS-VTEGNRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQE 989

Query: 1241 GLIEKFKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXX 1420
            GL++KFKL+TTISTSNMHLF+  GV+ KY +PE+I+EEF  LRLE+YE+RK  +L     
Sbjct: 990  GLLKKFKLTTTISTSNMHLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEF 1049

Query: 1421 XXXXXXNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NA 1558
                  NKVRFI  V++G+II+ NRKR+DL  EL QK FTP P+               A
Sbjct: 1050 ELLKLENKVRFILGVVRGEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAGATDDKDEA 1109

Query: 1559 XXXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDL 1738
                         Y+YLLSM IGTLT+EKVQ+LCA   KLN EVD LR  TP  LW+KDL
Sbjct: 1110 EDSLEVSGVRASDYDYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDL 1169

Query: 1739 DSLEQKLNLQSKIYDM----PEKRL--EVNAEISKRPKRTMRKKQESSEKKANNKDGLAE 1900
            ++LE +L++  K YD       K+L  + N E   +  +   K      KKA N++   E
Sbjct: 1170 EALEMQLDVLDK-YDAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKYTKKAINEEVSVE 1228

Query: 1901 ---KHTVPSDCTGKVPEAVELEGITTGR----DEISTPNPPSLDVNEDRGLEQKEEQPKQ 2059
               K +  +  T    E V+ +G    R     +   P+P S + +E   L+ + +  + 
Sbjct: 1229 TMGKASSSAMETENAAEVVKPKGRAGSRKAPAKKQEKPSPISDEDDEIESLKDRLKAYRL 1288

Query: 2060 SSSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTE 2185
             SSP+ S + +  VL+VP     R+ +     A +  ISD+E
Sbjct: 1289 DSSPEQSADMETEVLRVPA---GRKAARKKPLAAVSVISDSE 1327


>gb|PHU30239.1| DNA topoisomerase 2 [Capsicum chinense]
          Length = 1141

 Score =  818 bits (2114), Expect = 0.0
 Identities = 427/791 (53%), Positives = 553/791 (69%), Gaps = 39/791 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT ++G++L+FY++PEYE+W++SL   +SGWSIKYYKGLGTSTS
Sbjct: 223  LKVPSFLVEFITPIVKATHKSGRLLAFYTMPEYESWRKSLGATSSGWSIKYYKGLGTSTS 282

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGKEYFQDL+KH+KDF+W D +D ++IELAFSK KI+ARK WL+++EPGT+LDQKEK+I
Sbjct: 283  KEGKEYFQDLQKHRKDFVWADNQDGESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYI 342

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
             Y++FV+KELI FS+ADL RSIPSM+DG KPGQRKILF  FKRNF+KEAKV+Q SGYVSE
Sbjct: 343  SYTEFVNKELILFSMADLLRSIPSMLDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSE 402

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSL++TI+GMAQDY+GSNN+NLLQPNGQFGTR+ GGKDHAS+RYIYT LSPI
Sbjct: 403  HSAYHHGEQSLSSTIIGMAQDYVGSNNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPI 462

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
             RFLF K+DD +L YLNEDGQS+EPTWY+P+IPMVLVNG+EGIGTGWST++PNYNPRD+V
Sbjct: 463  ARFLFPKDDDTILDYLNEDGQSIEPTWYMPIIPMVLVNGSEGIGTGWSTFVPNYNPRDLV 522

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            ANVR  LNDE MEPM PWYKGF G IE T TK+ G ++ V GIIEEV++TT+RI+ELPVR
Sbjct: 523  ANVRRLLNDELMEPMDPWYKGFNGKIEKTLTKETGATFTVTGIIEEVDETTLRISELPVR 582

Query: 1079 KSTEEYKQFLDKLISKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEGLIEKF 1258
            + TE+YKQFL+ +     + K+QFIK+ R + D+ +V FE+ +SE+NL +A++EGL++KF
Sbjct: 583  RWTEDYKQFLETMTVSNDKAKDQFIKEVRAYGDENSVCFELILSEENLILAQQEGLLKKF 642

Query: 1259 KLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXXXXXXX 1438
            KL+ TISTSNMHLF+ KG + KY +PE+I+EEF       Y K    +L +         
Sbjct: 643  KLTNTISTSNMHLFDSKGKIKKYDTPEEILEEF-------YHKA---LLEILEFELLRVE 692

Query: 1439 NKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPRNAXXXXXXXXXXXXX------- 1597
            NKV+FI  V++G+II+ NRKR+DLL ELK K FTPFP+                      
Sbjct: 693  NKVKFILGVVKGEIIVNNRKRADLLLELKNKGFTPFPKKKAVEAVVADTTDDAEESEESP 752

Query: 1598 -----------YEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLDS 1744
                       Y+YLLSM IGTLT+EKVQELCA+R KLN EV+ +R+ATPK+LW+KDLD 
Sbjct: 753  EESNRGVRASDYDYLLSMAIGTLTLEKVQELCAERDKLNAEVEDMRNATPKTLWMKDLDV 812

Query: 1745 LEQKLNLQSKIYDMPEKRLEVNAEISKRPKRTMRKKQESSEKKANNKDGLAEKHTVPSDC 1924
            L+Q+L+ Q K+    E   E  A+I K+      K  +   +K N K  + E    P D 
Sbjct: 813  LDQQLDEQDKLDIQAE---EARAKIKKKVMNAAGKAPKPKPRKTNKKAAVVESIAEPMDV 869

Query: 1925 TG-------KVPEAVELEGITTGRDEISTPNPPSLDVNEDRGLEQKEEQPKQ-------- 2059
            +G        V E V+ +G   G  + +     S+ V E     + +E+  +        
Sbjct: 870  SGDSTTETANVTEVVKPKG-RGGGSKKAPAKAKSVAVEEKSVAVEDDEEDDEVLALKERL 928

Query: 2060 -----SSSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTEVDCENKQQTAETV 2224
                 +SSPD S   +    +   +   +R +A     P  ++SD            E  
Sbjct: 929  AAYNLNSSPDHSGVVETEAPKAQKKAPAKRAAAKKKTLPSTDVSD-----------GEDE 977

Query: 2225 IEISDSEVVCE 2257
            IEISD + V E
Sbjct: 978  IEISDDDDVFE 988


>ref|XP_011025468.1| PREDICTED: DNA topoisomerase 2-like isoform X4 [Populus euphratica]
          Length = 1478

 Score =  828 bits (2140), Expect = 0.0
 Identities = 431/769 (56%), Positives = 544/769 (70%), Gaps = 36/769 (4%)
 Frame = +2

Query: 2    LKIPTFLLEFITPIIKAT-RAGQVLSFYSIPEYEAWKQSLDGNNSGWSIKYYKGLGTSTS 178
            LK+P+FL+EFITPI+KAT R G VLSFYS+PEYE+WK+S  GN SGWSIKYYKGLGTSTS
Sbjct: 557  LKVPSFLVEFITPIVKATHRNGTVLSFYSMPEYESWKESSSGNASGWSIKYYKGLGTSTS 616

Query: 179  KEGKEYFQDLEKHKKDFLWLDKKDNDAIELAFSKHKIQARKKWLQKYEPGTYLDQKEKHI 358
            KEGK+YF++L KHKKDFLW+D+ D DAIELAFSK KI+ARK WL+++EPGT+LDQ +K I
Sbjct: 617  KEGKDYFKNLHKHKKDFLWMDELDGDAIELAFSKKKIEARKNWLRQHEPGTHLDQNQKLI 676

Query: 359  KYSDFVDKELIQFSVADLKRSIPSMVDGFKPGQRKILFSCFKRNFIKEAKVAQLSGYVSE 538
            KYSDF++KELI FS+ADL+RSIPSMVDG KPGQRKILF  FKRNF+KEAKV+Q SGYVSE
Sbjct: 677  KYSDFINKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSE 736

Query: 539  HSAYHHGEQSLANTIVGMAQDYMGSNNINLLQPNGQFGTRHQGGKDHASARYIYTCLSPI 718
            HSAYHHGEQSLA TI+GMAQD++GSNNINLLQPNGQFGTR  GGKDHASARYIYT LSPI
Sbjct: 737  HSAYHHGEQSLAGTIIGMAQDFVGSNNINLLQPNGQFGTRSVGGKDHASARYIYTQLSPI 796

Query: 719  TRFLFNKNDDALLHYLNEDGQSVEPTWYVPVIPMVLVNGTEGIGTGWSTYIPNYNPRDIV 898
            TRFLF K+DD LL+YL+EDGQ++EPTWY+P+IP VLVNG EGIGTGWST+IPNYNPRD+V
Sbjct: 797  TRFLFPKDDDGLLNYLDEDGQTIEPTWYIPIIPTVLVNGCEGIGTGWSTFIPNYNPRDVV 856

Query: 899  ANVRHFLNDEPMEPMIPWYKGFKGTIESTNTKDAGKSYVVKGIIEEVNKTTVRITELPVR 1078
            AN+R  LN E MEPM PWY+GFKGTIE   +K+ G SY V G+I EVN+TT+RITELP+R
Sbjct: 857  ANIRRLLNGEMMEPMNPWYRGFKGTIEKGASKEGGCSYTVNGLINEVNETTLRITELPIR 916

Query: 1079 KSTEEYKQFLDKLI-----SKGGRNKEQFIKDFREFNDDKTVHFEIYMSEKNLAMAKEEG 1243
            + T++YK FL+ +        G   K+ F+KDFR++ DD  VHFE+ +SE+N+ +AK+EG
Sbjct: 917  RWTDDYKAFLNSVTEGIRDENGNLPKDPFVKDFRKYGDDAAVHFEVQLSEENMLVAKQEG 976

Query: 1244 LIEKFKLSTTISTSNMHLFNPKGVLAKYSSPEKIIEEFCDLRLEFYEKRKIFMLSMXXXX 1423
            L++KFKL+TTISTSNMHLF+  GV+ KY +PE+I+E F  LRLE+YE RK  +L      
Sbjct: 977  LLKKFKLTTTISTSNMHLFDSAGVIKKYDNPEQILENFFHLRLEYYETRKKVLLENLEFE 1036

Query: 1424 XXXXXNKVRFIDEVIQGKIILMNRKRSDLLDELKQKNFTPFPR--------------NAX 1561
                 NKVRFI  V++G+II+ NRKR+DLL EL QK F P P+               A 
Sbjct: 1037 LLKLENKVRFILGVVRGEIIVNNRKRADLLLELHQKGFNPIPKKSKAVVAGATDDTEEAE 1096

Query: 1562 XXXXXXXXXXXXYEYLLSMPIGTLTMEKVQELCAQRKKLNVEVDGLRHATPKSLWLKDLD 1741
                        Y+YLLSM IGTLT+E+VQ+LCA R KLN EVD LR  TPK LW+KDL+
Sbjct: 1097 DSPDVSGVRASDYDYLLSMAIGTLTLERVQQLCADRDKLNGEVDSLRKTTPKVLWVKDLE 1156

Query: 1742 SLEQKLNLQSKIYDMPEKRL-----------EVNAEISKRPKRTMRK--KQESSEKKANN 1882
            +LE +L++  + YD   +             E   ++SK+  +  RK  K+  SE+ +  
Sbjct: 1157 ALEMQLDMLDE-YDAEAEEARRKLKGGGAKGETGFKVSKQAPKYPRKYTKKAISEEVSVE 1215

Query: 1883 KDGLAEKHTVPSDCTGKVPEAVELEGITTGRDEISTPNPPSLDVNED---RGLEQKEEQP 2053
              G +      ++    V +     G      ++   +P   D++ED     L+ +    
Sbjct: 1216 TTGTSSSFASETENAAVVVKPKGRAGSKKAPAKMEKLSPVLDDIDEDDEIESLKNRLNAY 1275

Query: 2054 KQSSSPDTSREPKMSVLQVPPEDNTRRNSADNLNAPIIEISDTEVDCEN 2200
            +  SSP+ S + +  VLQVP      R      N  +I  SD E + ++
Sbjct: 1276 RLDSSPEQSADMETDVLQVPARRGAARKK-PLANVSVISDSDDEPNLDD 1323