BLASTX nr result
ID: Papaver30_contig00016125
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Papaver30_contig00016125
(2442 letters)
Database: ./nr
77,306,371 sequences; 28,104,191,420 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas ... 140 4e-30
ref|XP_804789.1| R27-2 protein [Trypanosoma cruzi strain CL Bren... 132 2e-27
gb|EMD48416.1| viral Atype inclusion protein repeat-containing p... 129 2e-26
ref|XP_808187.1| myosin heavy chain [Trypanosoma cruzi strain CL... 127 6e-26
ref|XP_809970.1| hypothetical protein [Trypanosoma cruzi strain ... 125 2e-25
ref|XP_001305955.1| viral A-type inclusion protein [Trichomonas ... 124 4e-25
ref|XP_005159739.1| PREDICTED: uncharacterized protein si:ch211-... 124 5e-25
ref|XP_011428631.1| PREDICTED: golgin subfamily B member 1-like ... 121 3e-24
ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeb... 120 4e-24
ref|XP_004185542.1| myosin heavy chain, partial [Entamoeba invad... 118 3e-23
ref|XP_012262786.1| PREDICTED: myosin-2 heavy chain-like isoform... 117 5e-23
ref|XP_012262776.1| PREDICTED: major antigen-like isoform X1 [At... 117 5e-23
ref|XP_009292629.1| PREDICTED: nesprin-1 isoform X7 [Danio rerio] 116 8e-23
ref|XP_009292628.1| PREDICTED: nesprin-1 isoform X4 [Danio rerio] 116 8e-23
ref|XP_009292627.1| PREDICTED: nesprin-1 isoform X3 [Danio rerio] 116 8e-23
gb|KFM76401.1| Myosin heavy chain, non-muscle, partial [Stegodyp... 116 8e-23
ref|XP_005159743.1| PREDICTED: nesprin-1 isoform X6 [Danio rerio] 116 8e-23
ref|XP_685984.6| PREDICTED: nesprin-1 isoform X1 [Danio rerio] 116 8e-23
ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas ... 116 8e-23
ref|XP_001582797.1| viral A-type inclusion protein [Trichomonas ... 116 8e-23
>ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121900914|gb|EAY05939.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 5296
Score = 140 bits (354), Expect = 4e-30
Identities = 156/668 (23%), Positives = 286/668 (42%), Gaps = 28/668 (4%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAA 2262
+ ++K + + L+ LE K+AD E + D + LE
Sbjct: 4115 QDEEKSKLQQQLSDLQNKLNDLEKKLADKENEKEQEKTQKDDLQKQLDQLQKDFDNLERE 4174
Query: 2261 KQALENKVGDFEAAI----------ATLNDELLNEKDDKKCIVNDRNIVEADKQALENKV 2112
KQ L++K + I T+ D L + ++ K + ++ N + D Q +K
Sbjct: 4175 KQKLQDKNDSMKETIDSKNMLLDSFGTIKDHLNDANNNNKKLQDENNKLRDDAQKATSKN 4234
Query: 2111 ADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCI 1932
+ ++ I LN +L N +KK E K E K+ EA D+L ++ KK
Sbjct: 4235 NELQSIIDDLNRKLANLDAEKKATEEKLKNT-EDKLKQAEAEKKATEDKLRETENAKKET 4293
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQ 1752
E K+ +E K+A EAAK D+L++ +D+ A K + + +
Sbjct: 4294 EEKLAKTEEEKKQVEDKLAATEAAKKETEDKLKQTEDEKKATEDKLANVEAEKSDIEQAK 4353
Query: 1751 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK------ 1590
++ ED + + E ++L++ +D+K A+ +
Sbjct: 4354 KETEDKLKQTEEEKAAVEAEKKATEDKLHETEEAKKETEDKLKQTEDEKAAVEQAKKETE 4413
Query: 1589 -DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRK 1413
L E K+ + E++ + L E F E E+ S+L + + ++EL+
Sbjct: 4414 DKLKQTEEEKKATENKLEESEAEKKELGERF--ESSRGSTEKQVSDLENLLSKLKDELKN 4471
Query: 1412 EKDGKSALVENGEGCEAEKQGLE----KTVLERRASNLDTMDAIHEEELRKEKVDKSALT 1245
K+ KS L + EAEK+ E KT +E+ A E+ +KE DK A
Sbjct: 4472 IKEDKSQLESKLKQAEAEKKATEDKLAKTEVEKAAL----------EQAKKETEDKLANV 4521
Query: 1244 ENGE-GCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1068
EN + E +K K DL+ + L L+R +++ AEK+ALE++ + LE++ +
Sbjct: 4522 ENEKKATETQKNDLAKEKTDLQKALAKL---LKRQ-EQLDAEKKALEEKANALESEKKAT 4577
Query: 1067 TD---NQEGHEAEIERKLEAS--NLTHNDELHKEKDDK-ESIMNDLDHVKAERQVLESKV 906
+ N E + E + KL+ + NL ++ K +DK + ++ ++A ++ E K+
Sbjct: 4578 EEKLANAEKEKKETQDKLKQTEDNLAKSESEKKATEDKLKQTESEKAQIEAAKKETEDKL 4637
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD 726
+ E +L+Q + +A + EA K+ ++++ ++EA + + K
Sbjct: 4638 QNAENEKKAAEEKLKQSEEQKKATEEKLQEAEAEKKAEQEKLANIEAEKQQLGNASEKQV 4697
Query: 725 DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 546
E LK+ + +L EA ++ K +D ++ ++LQEDLN K+ +DLE
Sbjct: 4698 SDLSGEISKLKQLLKQLAEAKKKADEELAKSKQDKEQSDNDKSKLQEDLNNLKKQLEDLE 4757
Query: 545 KRVLELTS 522
K E S
Sbjct: 4758 KAKKESDS 4765
Score = 111 bits (277), Expect = 4e-21
Identities = 143/650 (22%), Positives = 276/650 (42%), Gaps = 21/650 (3%)
Frame = -2
Query: 2396 EAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQALENKVGDFEAAI 2217
E K+ LEN+ ++ E + I + + K LEN+ + + +
Sbjct: 3958 EEAKKNLENEKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLL 4017
Query: 2216 ATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE---LLNEKDD-K 2049
+ N +++K + E K+ LE + +D E + + +E L NEK++ +
Sbjct: 4018 EETEEAKKNLENEKAETQKKLDEAEEAKKNLEQEKSDAEKKLEEVQNEKSALENEKNETQ 4077
Query: 2048 KCIVEADK---QALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKV 1878
K + EA+K Q +E K +V + + D N+K + +++ L+ L+ K+
Sbjct: 4078 KKLEEAEKAKDQIVEEKSAVERQLVESQKDSSENQKQQDE----EKSKLQQQLSDLQNKL 4133
Query: 1877 ADLEAAKTTLNDELERKKDDNNAIIKKA--LDKRISDLKADAPQ-RDQEDDMNALIXXXX 1707
DLE +E E++K + + K+ L K +L+ + + +D+ D M I
Sbjct: 4134 NDLEKKLADKENEKEQEKTQKDDLQKQLDQLQKDFDNLEREKQKLQDKNDSMKETIDSKN 4193
Query: 1706 XXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES 1527
+++ N L +E K +DD + +N +++L++
Sbjct: 4194 MLLDSFGTIKDHLNDANNNNKKLQDENNKLRDDAQKATSKNNELQSIIDDLNRKLANLDA 4253
Query: 1526 KSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 1347
+ ++ +E L+ ED++ + A K E++LR+ ++ K E E EK+ +
Sbjct: 4254 EKKATEEK-LKNTEDKLKQAEAE-----KKATEDKLRETENAKKETEEKLAKTEEEKKQV 4307
Query: 1346 EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPS 1167
E + A+ +T E++L++ + +K A + EAEK E+ + E +
Sbjct: 4308 EDKLAATEAAKKET-----EDKLKQTEDEKKATEDKLANVEAEKSDIEQAKKETEDKLKQ 4362
Query: 1166 LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELH 987
+ + V AEK+A E + + E D + E E + +E + D+L
Sbjct: 4363 TEE----EKAAVEAEKKATEDKLHETEEAKKETEDKLKQTEDE-KAAVEQAKKETEDKLK 4417
Query: 986 KEKDDKESIMNDLDHVKAERQVL-----------ESKVSDMETTYSTLNNELQQKMDDNE 840
+ +++K++ N L+ +AE++ L E +VSD+E S L +EL+ +D
Sbjct: 4418 QTEEEKKATENKLEESEAEKKELGERFESSRGSTEKQVSDLENLLSKLKDELKNIKED-- 4475
Query: 839 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS 660
K LE ++ EA E K K E EK L++ E E+ ++
Sbjct: 4476 ------------KSQLESKLKQAEAEKKATEDKLAK----TEVEKAALEQAKKETEDKLA 4519
Query: 659 ILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
+ ++ K TE Q+ N +KEK DL+K + +L + E+
Sbjct: 4520 NVENEKK------------ATETQK--NDLAKEKTDLQKALAKLLKRQEQ 4555
Score = 109 bits (272), Expect = 1e-20
Identities = 152/694 (21%), Positives = 281/694 (40%), Gaps = 60/694 (8%)
Frame = -2
Query: 2396 EAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQALENKVGDFEAAI 2217
E K+A E+K+A+ E + K ++ +EA K+A E+K+ + E A
Sbjct: 4329 EDEKKATEDKLANVEAEKSDIEQAKKETEDKLKQTEEEKAAVEAEKKATEDKLHETEEAK 4388
Query: 2216 ATLNDELLNEKDDKKCIVNDRNIVE-------ADKQALENKVADFEATIATLNDELLNEK 2058
D+L +D+K + + E +K+A ENK+ + EA L +
Sbjct: 4389 KETEDKLKQTEDEKAAVEQAKKETEDKLKQTEEEKKATENKLEESEAEKKELGERF---- 4444
Query: 2057 DDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKV 1878
E+ + + E +VS E ++ L DEL N K+DK + + EA K+A E K+
Sbjct: 4445 -------ESSRGSTEKQVSDLENLLSKLKDELKNIKEDKSQLESKLKQAEAEKKATEDKL 4497
Query: 1877 ADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 1698
A E K L + KK+ + + +K+ ++ + + +++ D AL
Sbjct: 4498 AKTEVEKAALE---QAKKETEDKLANVENEKKATETQKNDLAKEKTDLQKAL-------- 4546
Query: 1697 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 1518
+L E+L EK AL + A E K+ E +++ E + +
Sbjct: 4547 --------------AKLLKRQEQLDAEKK---ALEEKANALESEKKATEEKLANAEKEKK 4589
Query: 1517 SLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEK--DGKSALVENGEGCEAEKQGLE 1344
++ L++ ED + + + A +++ E K + K + + E EK+ E
Sbjct: 4590 ETQDK-LKQTEDNLAKSESEKKATEDKLKQTESEKAQIEAAKKETEDKLQNAENEKKAAE 4648
Query: 1343 KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ----GPEKTVLDLEPT 1176
+ + + T EE+L++ + +K A E EAEKQ EK V DL
Sbjct: 4649 EKLKQSEEQKKAT-----EEKLQEAEAEKKAEQEKLANIEAEKQQLGNASEKQVSDLSGE 4703
Query: 1175 IPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG---------------HEA 1041
I L L++ + + L K D E + + QE E+
Sbjct: 4704 ISKLKQLLKQLAEAKKKADEELAKSKQDKEQSDNDKSKLQEDLNNLKKQLEDLEKAKKES 4763
Query: 1040 EIERKLEASNLTHNDELHKEKDDK-----------ESIMNDLDHVKAERQVLE-SKVSD- 900
+ KL A ++ E +K+KDD+ + I N+ D VK ++ L+ SK ++
Sbjct: 4764 DSNNKLLADSVNKLKEQNKQKDDEIKNLTDKANQPQDINNNPDFVKVKKAFLQLSKTNEK 4823
Query: 899 -----------METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD------L 771
+ + YST+ + +D+ + + + + + Q + +D L
Sbjct: 4824 LENEKKALEGAVNSIYSTMKKDDSAPLDEKATPMQQAERAKELIQNNSGKKVDPEFFEKL 4883
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
++D+ K N +KK EE I+ + + L K + S +T+L
Sbjct: 4884 TNEMNDLFNSICKVFRTNSPITFDIKK-----EEDIATIGQNSIVLRK---VMKSYLTQL 4935
Query: 590 QEDLNKESKEKQDL--EKRVLELTSKLEKCICGA 495
D+ K+ ++ DL +K L++ ++ K A
Sbjct: 4936 SNDIIKDKQQISDLKHDKNSLQMENEEIKATASA 4969
Score = 107 bits (266), Expect = 7e-20
Identities = 134/634 (21%), Positives = 271/634 (42%), Gaps = 38/634 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN 2118
++ N++ +E K L+ ++G E+ N+ L+ K D K ND+ + D+ EN
Sbjct: 2996 NLSNEKKQIETEKNGLQGQIGRLESQ----NESLIESKKDMK-EQNDKLQAQMDEMRREN 3050
Query: 2117 K-VADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDK 1941
+ + + N+ L N+ + L +++ + ++ L D+L +++++
Sbjct: 3051 NSLRQNQTQLERTNNGLENKVGN-----------LTDQLNQVKNQLSALQDQLKSKENEN 3099
Query: 1940 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
+ + N+R L K ++E + D +A L + E D N++ + + ++ K +
Sbjct: 3100 EKLRNEREKLANEKNSVELQSKDKDAEIIKLKSDAEHLNDKINSLNDEKNKLQQANDKLN 3159
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTA------ 1599
+ +N L + + N+E + L EE K +D+ +
Sbjct: 3160 DQIEQMKQQINNLTNENKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQ 3219
Query: 1598 LIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
+KD + K +E + L +S S E+ E+L + +L + + E+L
Sbjct: 3220 RLKDTIKELSDKLAKSEEDNKLLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNS-ENEQL 3278
Query: 1418 RKEKDGKSALVENGEG----CEAEKQGLEKTVLERRASNLDTM-----DAIHEE---ELR 1275
+++KD S + N E + + L K LE+ + + M +AI ++ E+
Sbjct: 3279 KQQKDQLSEKLNNSNNDKTKAETQNEQLSKQ-LEQLNNEKNQMFNKYKNAIQDKAKVEIA 3337
Query: 1274 KEKV---------DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAE 1122
KE + +K +L + + EK E+ LE LNDA + E
Sbjct: 3338 KETLAKDNEKLASEKESLQQKLDSANDEKNKLEQDKHKLEIDNTKLNDAKSH----LENE 3393
Query: 1121 KQALEKRCSDLEAKNASLTDNQ---EGHEAEIERKLEASNLTHNDELHKEKDDK----ES 963
K L ++ +DL K L + + E +A+ E+KLE S D+L ++ D E
Sbjct: 3394 KSQLAQQINDLNNKLQKLEEEKNKLEEEKAQNEKKLENSQ-QDGDKLGQQNQDLLKQLEE 3452
Query: 962 IMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKR 783
I L + E+ LE + ++++ + + +++ + E + +E K +K+
Sbjct: 3453 IKQKLQQTEQEKSALEQQKNEIQNKLNEIEQQMKDSEKEKEDIKQKLQQVEQEKSETQKK 3512
Query: 782 VLDLEATIHDIEMK---TGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 612
+ + E ++I+ K T ++ E EK +KR+ E EEA L ++ + + +
Sbjct: 3513 LEEAEQQKNEIQNKLEQTEQEKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEEV 3572
Query: 611 LSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
+E E + LN+ + ++LE E KLE+
Sbjct: 3573 QNEKAETERKLNEAEEANKNLENEKNETQKKLEE 3606
Score = 105 bits (262), Expect = 2e-19
Identities = 125/610 (20%), Positives = 256/610 (41%), Gaps = 18/610 (2%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
D L AK LEN+ I LN++L +++K + ++ +++ LEN D
Sbjct: 3379 DNTKLNDAKSHLENEKSQLAQQINDLNNKLQKLEEEKNKLEEEK---AQNEKKLENSQQD 3435
Query: 2105 FEATIATLNDELLNEKDDKKCIV---EADKQALESKVSVFEAAIATLNDELLNEKDDKKC 1935
+ + N +LL + ++ K + E +K ALE + + + + + ++ + + +K+
Sbjct: 3436 GDK-LGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQKNEIQNKLNEIEQQMKDSEKEKED 3494
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAP 1755
I +E K + K+ + E K + ++LE+ + + K + + KA+
Sbjct: 3495 IKQKLQQVEQEKSETQKKLEEAEQQKNEIQNKLEQTEQEK---------KNLENEKAETE 3545
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
+R QE + + NL +L++ +++K + L A
Sbjct: 3546 KRLQETE-------------------EAKKNLANEKSEAERKLEEVQNEKAETERKLNEA 3586
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSAS---NLAIMKAIREEELRKEKD 1404
E + + + + K ++ + E ++LE++ NLA K+ E +L++ ++
Sbjct: 3587 EEANKNLENEKNETQKKLEEAEQQ--KAETQKLLEQTEEAKKNLANEKSEAERKLQETEE 3644
Query: 1403 GKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
K L E + + + EK ER+ + + + + L EK + E E
Sbjct: 3645 AKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEAN----KNLENEKNETQKKLEEAEQ 3700
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+AE Q + + + + + +R L K+ L S+ E K + +
Sbjct: 3701 QKAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERK----LEEVQN 3756
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 870
+AE ERKL + N L EK++ + + + + KAE Q L + + + +
Sbjct: 3757 EKAETERKLNEAEEA-NKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKS 3815
Query: 869 ELQQKMDDNEAFLNERDGLEAVKQGLEKRV-------LDLE---ATIHDIEMKTGKDDDY 720
E ++K+ + E + LE K ++K++ ++LE A + +T +
Sbjct: 3816 ETEKKLQETE---EAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKKN 3872
Query: 719 NEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
E EK +KR+ E EEA L ++ + + + +E E + LN+ + ++LE
Sbjct: 3873 LENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENE 3932
Query: 539 VLELTSKLEK 510
E KLE+
Sbjct: 3933 KNETQKKLEE 3942
Score = 94.7 bits (234), Expect = 3e-16
Identities = 133/622 (21%), Positives = 259/622 (41%), Gaps = 41/622 (6%)
Frame = -2
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQAL--------ENKVADFEA 2097
+ +++G + L +E + K++ + ++N +E +KQ L ENK ++
Sbjct: 2771 VHHQLGALQEKATNLENENKSLKEENEDLMNQNKQLEKEKQQLLAQNSNLEENKNNQEQS 2830
Query: 2096 TI--ATLNDELLNEKDDKKCIVEADKQ---ALESKVSVFEAAIATLNDELLNEKDDKKCI 1932
+ ND+LL + DD K +E K+ E+K+ I + D++ N+K+ K
Sbjct: 2831 LMNRKKKNDDLLKQIDDLKLELEELKRNNSQNETKLQNANQQIEMMKDQINNDKEQIKSA 2890
Query: 1931 VNDRN--------------ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 1794
+ N +LE K+ E D++++ LNDE +K D + K+
Sbjct: 2891 QDKLNDLQNKNNELNSNQIVLENQKKMYEGLYNDMKSSNDKLNDENRKKTDQIIDLTKQ- 2949
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV--NILILHEELQK 1620
+ +S LK + + + E K+ SN V N L +++++
Sbjct: 2950 -NAEVSALKLENQRLNSE-------------------LEKLKSNQPVSSNDPELQKQIEE 2989
Query: 1619 EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNLAI 1446
K L + E K + + LES++ SL E ++E+ D++
Sbjct: 2990 LKKQLNNLSNEKKQIETEKNGLQGQIGRLESQNESLIESKKDMKEQNDKL---------- 3039
Query: 1445 MKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEK 1266
+ +E+R+E ++L +N E GLE V NL ++L + K
Sbjct: 3040 --QAQMDEMRRE---NNSLRQNQTQLERTNNGLENKV-----GNL-------TDQLNQVK 3082
Query: 1265 VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLE 1086
SAL + + E E N+ L+ + +++ EK ++E + D +
Sbjct: 3083 NQLSALQDQLKSKENE------------------NEKLRNEREKLANEKNSVELQSKDKD 3124
Query: 1085 AKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQ 924
A+ L + E +I + KL+ +N ND++ + K ++ N+ +++ E+
Sbjct: 3125 AEIIKLKSDAEHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNLTNENKNMEQEKA 3184
Query: 923 VLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 744
+ K+ ++E L E + D+N NE + L+ TI ++
Sbjct: 3185 KNQEKIQNIEPKLKQLEEEKSKLEDENSQNENE--------------IQRLKDTIKELSD 3230
Query: 743 KTGKDDDYNEAEKQ----TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN 576
K K ++ N+ KQ T K++ +L+E ++ L D K L + + +L E LN
Sbjct: 3231 KLAKSEEDNKLLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNSENEQLKQQKDQLSEKLN 3290
Query: 575 KESKEKQDLEKRVLELTSKLEK 510
+ +K E + +L+ +LE+
Sbjct: 3291 NSNNDKTKAETQNEQLSKQLEQ 3312
Score = 94.4 bits (233), Expect = 4e-16
Identities = 139/662 (20%), Positives = 276/662 (41%), Gaps = 76/662 (11%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLN----DELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
+E Q L+NK+ D E+ I LN +++D K+ I N ++ K+ +E+K +
Sbjct: 372 IENEVQNLKNKIADRESQIKALNLLIAQYQTDDEDKKEIIENLEKEIKDLKKQIEDKDKE 431
Query: 2105 FEATIATLN--DELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDEL--LNEK-DDK 1941
E A + +E+ +++D+ +V + + EA +L D++ L EK DDK
Sbjct: 432 IEVLKAKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDDK 491
Query: 1940 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDN------------------ 1815
K +N ++ KQAL K A++E LN++++ KD N
Sbjct: 492 K-----KNGVQM-KQALASKDAEIEK----LNEQIQELKDRNDKQEQNIEELNTKNSDLQ 541
Query: 1814 --NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV---- 1653
N KK +D+ + LK A + + D+N + SN E+
Sbjct: 542 NSNDEYKKLIDELQNQLKDLAKNKAESSDLNNSENTKQDSEKAEDENAETKSNKELQEES 601
Query: 1652 ---------------NILILHEELQKEKDDKTALIKDLVAA-EPGKRTVNEI-------- 1545
N+ +++L K +DK IK+L + K +NE+
Sbjct: 602 DKLKSENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKD 661
Query: 1544 --VSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAI---REEELRKEKDGKSALVEN 1380
+ L SK S++ L ++ED++ ++++ + I E E + E + + EN
Sbjct: 662 REIEILSSKVSSIENVNLDDDEDDITVVGTRDISVDETIPTDNETETKTEPETNTNTNEN 721
Query: 1379 GEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK 1200
E N+ + + +EE+ + ++ K + + A KQG
Sbjct: 722 TN--------------ETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVD 767
Query: 1199 TVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEA-KNASLTDNQEGHEAEIERKL 1023
+ + S N+ L + + + + LE+ ++ K + D +E + E+
Sbjct: 768 ALKSQNDDLKSENETLSKSNHELETKNKELEEEIENINNNKEGEVIDEKEASDVEVVCST 827
Query: 1022 EASNLTHNDELHKE--KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 849
+ + +E E K +S +++L++++ E L ++ +++ L EL+
Sbjct: 828 RDVDFEYENENDPETLKSLLKSKLSELENLQKENTDLMKQIEELKNENENLKRELENLKL 887
Query: 848 DNEAFLNERDGLEAVKQG-----------LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ 702
+NE+ E + L+ L ++ LE+ + +++ KT NE E+
Sbjct: 888 ENESLKRENERLQLTADQSPQSKDKMIELLANQINQLESLVPELQQKT------NEIEE- 940
Query: 701 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 522
LKK +++E +K KK +D+ S + E++N +E++DL+K++ +L
Sbjct: 941 -LKKENKQIKEE----NEKLKKENEDLK--KSGSNKSSEEIN---QEEEDLKKQIEDLKK 990
Query: 521 KL 516
L
Sbjct: 991 AL 992
Score = 93.6 bits (231), Expect = 8e-16
Identities = 128/635 (20%), Positives = 263/635 (41%), Gaps = 48/635 (7%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
E K ALE + + + + + ++ + + +K+ I VE +K + K+ + E
Sbjct: 3461 EQEKSALEQQKNEIQNKLNEIEQQMKDSEKEKEDIKQKLQQVEQEKSETQKKLEEAEQQK 3520
Query: 2090 ATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
+ ++L + +KK + E +K E ++ E A L +E + + + N++
Sbjct: 3521 NEIQNKLEQTEQEKKNL-ENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAET 3579
Query: 1910 EAAKQALEYKVADLEAAKTTLN---DELERKKDDNNAIIKKALD--KRISDLKADAPQRD 1746
E E +LE K +E E++K + ++++ + K +++ K++A ++
Sbjct: 3580 ERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLANEKSEAERKL 3639
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG 1566
QE + + NL +L++ +++K + L AE
Sbjct: 3640 QETE-------------------EAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEA 3680
Query: 1565 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSAS---NLAIMKAIREEELRKEKDGKS 1395
+ + + + K ++ + E ++LE++ NLA K+ E +L++ ++ K
Sbjct: 3681 NKNLENEKNETQKKLEEAEQQ--KAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKK 3738
Query: 1394 ALVENGEGCEA-------EKQGLEKTVLERRASNLDTMDAIHE-----EELRKEKVDKSA 1251
L E EK E+ + E +N + + +E EE ++K +
Sbjct: 3739 NLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQK 3798
Query: 1250 LTENGE----GCEAEKQGPEKTVLDLEPTIPSLNDA---LQRDLDRVMAEKQALEKRCSD 1092
L E E E EK EK + + E +L +Q+ LD +K LE ++
Sbjct: 3799 LLEQTEEAKKNLENEKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAE 3858
Query: 1091 LEA---KNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV 921
+ + N E +AE E++L+ + + L EK + E + ++ + KAE +
Sbjct: 3859 TQKLLEETEEAKKNLENEKAETEKRLQETEEAKKN-LANEKSEAERKLEEVQNEKAETER 3917
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEA------------------FLNERDGLEAVKQG 795
++ + NE Q+K+++ E NE+ E Q
Sbjct: 3918 KLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQE 3977
Query: 794 LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 615
E+ +LE DI+ K D + +K L+ +E ++ + T++AKK L+
Sbjct: 3978 TEEAKKNLEQEKSDIQKKL----DETKQQKVNLENEKAETQKLLE-ETEEAKKNLE---- 4028
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
+E E Q+ L++ + K++LE+ + KLE+
Sbjct: 4029 --NEKAETQKKLDEAEEAKKNLEQEKSDAEKKLEE 4061
Score = 91.7 bits (226), Expect = 3e-15
Identities = 148/717 (20%), Positives = 298/717 (41%), Gaps = 133/717 (18%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVND----------------RNIVE- 2142
+A ++ L I TL+DEL NE++ ++ ++ D N++E
Sbjct: 2412 DAKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNNKEPEKDDNGDFMNVLEK 2471
Query: 2141 -----------------------ADKQALENK--VADFEATIATLND------------- 2076
D++A +NK V D + IA LN+
Sbjct: 2472 KSDEINKALEEILHRQNEEIKALRDREAEKNKQTVDDLQKQIAMLNNKLKPSDQTDNDQL 2531
Query: 2075 --ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAA 1902
EL+ ++ + + + +K+ L++ F IA L + + N+ ++ K + + ++A
Sbjct: 2532 QKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESINNQNEELKKLRQKCDGVDAI 2591
Query: 1901 KQALEYKVADLEAAKTTLND---ELERKKDDNNAIIK---KALDKRISDL---------K 1767
+ L K A+L K E E++ ++NN +K AL+ R+
Sbjct: 2592 ELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTINALENRLDSQGEQTRSKINS 2651
Query: 1766 ADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD---KTAL 1596
A+ R ++D ++ + ++NL+ +L ++L+ EK++ +
Sbjct: 2652 AEQTARKAKEDADSAVIAQKSLQAE-------LNNLKQKYAVLEDQLKTEKENHQQEAQQ 2704
Query: 1595 IKDLVAAEPGK----RTVNEIVSHLESKSRSLKEH------FLREEEDEV------LERS 1464
+K+L + V E + L++ + L E+ + E +D++ ++
Sbjct: 2705 LKELAEEDATPMVCIHVVGEKLKKLQNDNEKLSENNDNLQKNINELKDKINGLEKQYKQD 2764
Query: 1463 ASNLA----IMKAIREEELRKEKDGKSALVENGEGCEAEKQ-GLEKTVLERRASNLDTMD 1299
A+ L+ + A++E+ E + KS EN + KQ EK L + SNL+
Sbjct: 2765 AAELSNVHHQLGALQEKATNLENENKSLKEENEDLMNQNKQLEKEKQQLLAQNSNLEENK 2824
Query: 1298 AIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1119
E+ L K L + + + E + ++ E + + N ++ D++ +K
Sbjct: 2825 NNQEQSLMNRKKKNDDLLKQIDDLKLELEELKRNNSQNETKLQNANQQIEMMKDQINNDK 2884
Query: 1118 QAL---EKRCSDLEAKNASLTDNQEGHEAE------IERKLEASNLTHNDELHKEKD--- 975
+ + + + +DL+ KN L NQ E + + +++SN NDE K+ D
Sbjct: 2885 EQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGLYNDMKSSNDKLNDENRKKTDQII 2944
Query: 974 DKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN--ELQQKMDDNEAFL----NERDGL 813
D ++ +K E Q L S++ +++ +N ELQ+++++ + L NE+ +
Sbjct: 2945 DLTKQNAEVSALKLENQRLNSELEKLKSNQPVSSNDPELQKQIEELKKQLNNLSNEKKQI 3004
Query: 812 EAVKQGLEKRVLDLEATIHDI-----EMKTGKDD-----DYNEAEKQTLKKRISELEEAI 663
E K GL+ ++ LE+ + +MK D D E +L++ ++LE
Sbjct: 3005 ETEKNGLQGQIGRLESQNESLIESKKDMKEQNDKLQAQMDEMRRENNSLRQNQTQLERTN 3064
Query: 662 SILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDL---------EKRVLELTSK 519
+ L +K L +N ++++ LQ+ L + E + L EK +EL SK
Sbjct: 3065 NGLENKVGNLTDQLNQVKNQLSALQDQLKSKENENEKLRNEREKLANEKNSVELQSK 3121
Score = 81.6 bits (200), Expect = 3e-12
Identities = 127/609 (20%), Positives = 275/609 (45%), Gaps = 32/609 (5%)
Frame = -2
Query: 2249 ENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDEL 2070
ENK + E I LN+EL +D K+ R + E ++ L N+ I TL+DEL
Sbjct: 2392 ENKAKEDE--ITKLNEELAKSEDAKR-----RELAETAER-LNNE-------INTLHDEL 2436
Query: 2069 LNEKDDKKCIVE--------ADKQALESKVSVFEAAIATLN---DELLNEKDDKKCIVND 1923
NE++ ++ ++E +K ++V E +N +E+L+ ++++ + D
Sbjct: 2437 QNEQNARQKLIEDLQSNNKEPEKDDNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRD 2496
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQ 1743
R E KQ ++ DL+ LN++L+ +N ++K L +++ ++P+
Sbjct: 2497 REA-EKNKQTVD----DLQKQIAMLNNKLKPSDQTDNDQLQKEL--MFQEIEGESPEDRN 2549
Query: 1742 EDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK--EKDDKTALIKDLVAAEP 1569
+ + A+ +I++ L+ +I +EEL+K +K D I+ +A +
Sbjct: 2550 KRYLKAI----------EDKFNEIIAKLQESINNQNEELKKLRQKCDGVDAIELQLAQK- 2598
Query: 1568 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 1389
K +NEI + E + ++ EE ++ L+ + + L + E+ R + +
Sbjct: 2599 -KAELNEIKDNYEKEKAEREKEV--EENNKKLKDTINALENRLDSQGEQTRSKINSAEQT 2655
Query: 1388 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1209
+ +A+ + + L+ +NL A+ E++L+ EK + + + E
Sbjct: 2656 ARKAKE-DADSAVIAQKSLQAELNNLKQKYAVLEDQLKTEKENHQQEAQQLKELAEEDAT 2714
Query: 1208 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1029
P + + + L Q D +++ L+K ++L+ K L + AE+
Sbjct: 2715 PMVCIHVVGEKLKKL----QNDNEKLSENNDNLQKNINELKDKINGLEKQYKQDAAELSN 2770
Query: 1028 --------KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 873
+ +A+NL + ++ KE++ E +MN ++ E+Q L ++ S++E +
Sbjct: 2771 VHHQLGALQEKATNLENENKSLKEEN--EDLMNQNKQLEKEKQQLLAQNSNLEENKNNQE 2828
Query: 872 NELQQKMDDNEAFLNERDG----LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEK 705
L + N+ L + D LE +K+ + L+ IEM KD N+ E+
Sbjct: 2829 QSLMNRKKKNDDLLKQIDDLKLELEELKRNNSQNETKLQNANQQIEMM--KDQINNDKEQ 2886
Query: 704 -QTLKKRISELE------EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 546
++ + ++++L+ + I+ + KK+ + + +++ + LN E+++K D
Sbjct: 2887 IKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGL---YNDMKSSNDKLNDENRKKTD-- 2941
Query: 545 KRVLELTSK 519
++++LT +
Sbjct: 2942 -QIIDLTKQ 2949
Score = 75.9 bits (185), Expect = 2e-10
Identities = 162/684 (23%), Positives = 280/684 (40%), Gaps = 103/684 (15%)
Frame = -2
Query: 2252 LENKVGDFEAAIATLND--------ELLNEKDDKKCIVND-RNIVEADKQALENKVADFE 2100
L+ KV D E A+ +D ELL E D+ K +D + + + E+K
Sbjct: 1448 LKKKVEDLEKALGYPSDGKDHKSPSELLKENDELKKQNDDLKKALGYPEDGKEHKSPS-- 1505
Query: 2099 ATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDD-KKCIVND 1923
EL+ E ++ K K L + S A +EL NE ++ KK I
Sbjct: 1506 --------ELIKENEELK-----KKLGLSEESSTDSKADNKSPEELKNENNELKKQIEAL 1552
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD--------KRISDLK 1767
+ +L + E+K E K N+EL+++ D+ +K+AL K S+L
Sbjct: 1553 KRVLGYPEDGNEHKTPS-ELIKE--NEELKKQNDN----LKRALGYPEDGKDHKSPSELI 1605
Query: 1766 ADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD--KTAL 1596
A+ + +E DD+ + I N EEL+KE DD K
Sbjct: 1606 AEIEELKKENDDLKRALGYPEDDKDHKSPSELIKEN---------EELKKENDDLKKRLG 1656
Query: 1595 IKDLVAAEPGKRTVNEIVSHLESKSRSL------KEHFLREE---EDEVLERSASNLAIM 1443
I +AE + E+ +E ++L KEH E E+E L++ N A+
Sbjct: 1657 ISGESSAEESN-SPEELKKQIEDLKKALGYPEDGKEHKTPSELIKENEELKKQ--NDALK 1713
Query: 1442 KAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV---------------------LER 1326
+A+ E K+ S L++ E + + + LEK + L++
Sbjct: 1714 RALGYPEDGKDHKSPSELIQENEELKKKVEDLEKALGYPQDGKDHKSPSELLKENEELKK 1773
Query: 1325 RASNLD---TMDAIHEEELR------KEKVD--KSALTENGEGCE--------AEKQGPE 1203
+ D T D EEL+ K++++ K AL +G E E + +
Sbjct: 1774 KLGISDESSTEDNKSPEELKNENKYLKKQIEGLKKALGYPEDGKEHKSPSELIQENEDLK 1833
Query: 1202 KTVLDLEPTIPSLNDALQ-RDLDRVMAEKQALEKRCSDLEAKNASL-------------- 1068
K V DLE + D + + ++ E + L+K L+ +NA L
Sbjct: 1834 KKVSDLEKALGYPEDGKEHKSPSELLKENEELKKENQRLKKENAELKKRLGIPVDQIIEG 1893
Query: 1067 -------TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESK 909
+D E +++ E K E NL E K +E++ + + +K L
Sbjct: 1894 IMNESTASDESEDNKSPEELKREIENLKKQLEDLKNSGSQENVDEENNEMKEGADNLIDA 1953
Query: 908 VSDMETTYSTLNNELQQKMDDN----EAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
+ + ++LQQK+DD E + + +E + + + + + +T D+E++
Sbjct: 1954 LQQSVDEKNKQIDDLQQKLDDQNREIELLKAKVEQIENINEEEDNEDIVVAST-RDVELE 2012
Query: 740 TGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS---EVTELQEDLNKE 570
+++ EA K+ L ++IS+L++ LT+K K L+ S E+++L E++ +
Sbjct: 2013 NVEEESPEEA-KERLAEQISQLQDK---LTEKKKNSLQMKQALASKDAEISKLNEEIEQI 2068
Query: 569 SKEKQD----LEKRVLELTSKLEK 510
EK+D LEK ELT LEK
Sbjct: 2069 KSEKEDQDKELEKLNNELTEALEK 2092
Score = 74.3 bits (181), Expect = 5e-10
Identities = 150/691 (21%), Positives = 267/691 (38%), Gaps = 63/691 (9%)
Frame = -2
Query: 2399 LEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQALEN-KVGDFEA 2223
L + ENK+ + E+ I+ K + IL + ++EN + D E
Sbjct: 625 LNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDED 684
Query: 2222 AIATLN------DELL---NEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDEL 2070
I + DE + NE + K + N E + E V+ E N+E
Sbjct: 685 DITVVGTRDISVDETIPTDNETETKTEPETNTNTNENTNETNEENVSSQEGN----NEEK 740
Query: 2069 LNEKDDKKCI-VEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
K+DKK + ++ KQ L SK +A + + ND+L +E + L +
Sbjct: 741 NQSKEDKKKLRIQQLKQLLASKQGEVDA-LKSQNDDLKSENET----------LSKSNHE 789
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXX 1713
LE K +LE +N+ E + D +K SD++ RD + +
Sbjct: 790 LETKNKELEEEIENINNNKEGEVID---------EKEASDVEVVCSTRDVDFEYE----- 835
Query: 1712 XXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHL 1533
+ + +L + L E LQKE D L+K + + + + +L
Sbjct: 836 -------NENDPETLKSLLKSKLSELENLQKENTD---LMKQIEELKNENENLKRELENL 885
Query: 1532 ESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQ 1353
+ ++ SLK E+E L+ +A K E L + + +LV + E +
Sbjct: 886 KLENESLKR------ENERLQLTADQSPQSKDKMIELLANQINQLESLVPELQQKTNEIE 939
Query: 1352 GLEKTVLERRASNLDTMDAIHEEELRKEKVD--KSALTENGEGCEAEKQGPEKTVLDLEP 1179
L+K + + N E+L+KE D KS ++ E E++ +K + DL+
Sbjct: 940 ELKKENKQIKEEN---------EKLKKENEDLKKSGSNKSSEEINQEEEDLKKQIEDLKK 990
Query: 1178 TIPSLNDALQRDL-DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTH 1002
+ D + ++ E + L+K+ DLE ++ +DN+ E K + L
Sbjct: 991 ALGYPQDGKEHKTPSELIEENEELKKKVEDLEKESGYPSDNK-------EHKSPSELLKE 1043
Query: 1001 NDELHKEKDDKE----------------SIMNDLDHVKAERQVL--------ESKVSDME 894
N+EL K+ DD E ++ + + +K + L + K
Sbjct: 1044 NEELKKKVDDLEKALGYPEDGKDHKSPSELIKENEELKKQNDALKRALGYPEDGKDHKSP 1103
Query: 893 TTYSTLNNELQQKMDDNEAFL-------NERDGLEAVKQGLE-KRVLDLEATIHDIEMKT 738
+ N EL++K+ D E L + E +++ E K+ L + + + +
Sbjct: 1104 SELIQENEELKKKVADLEKALGYPADGQEHKTPSELLRENEELKKKLGISDSTTPSDNED 1163
Query: 737 GKDDDYNEAEKQTLKKRISELEEAISILTD-----------KAKKLLKDINIWLSEVTEL 591
K + +E + LKK+I +L+ A+ D K + LK N L +
Sbjct: 1164 NKSPEELRSENKDLKKQIEDLKRALGYPEDGKEHKTPSELIKENEELKKQNDSLKKALGY 1223
Query: 590 QEDLNKES------KEKQDLEKRVLELTSKL 516
ED KE +DL+K+V +L L
Sbjct: 1224 SEDGKDHKSPSELIKENEDLKKKVEDLEKAL 1254
Score = 69.7 bits (169), Expect = 1e-08
Identities = 134/644 (20%), Positives = 270/644 (41%), Gaps = 62/644 (9%)
Frame = -2
Query: 2258 QALENKVGDFEAAIATLND--------ELLNEKDD--KKCIVNDRNIVEADK--QALENK 2115
+ L+ KV D E A+ D ELL E ++ KK ++D + E +K + L+N+
Sbjct: 1736 EELKKKVEDLEKALGYPQDGKDHKSPSELLKENEELKKKLGISDESSTEDNKSPEELKNE 1795
Query: 2114 VADFEATIATLNDELLNEKDDKK----CIVEADKQALESKVSVFEAAIATLNDELLNEKD 1947
+ I L L +D K+ + + + L+ KVS E A+ D E
Sbjct: 1796 NKYLKKQIEGLKKALGYPEDGKEHKSPSELIQENEDLKKKVSDLEKALGYPEDG--KEHK 1853
Query: 1946 DKKCIVNDRNILEAAKQALEYKVADLEAA--------------KTTLNDELERKKDDNNA 1809
++ + L+ Q L+ + A+L+ ++T +DE E K
Sbjct: 1854 SPSELLKENEELKKENQRLKKENAELKKRLGIPVDQIIEGIMNESTASDESEDNKSPEE- 1912
Query: 1808 IIKKALD---KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1638
+K+ ++ K++ DLK Q + +++ N + ++ L+ ++
Sbjct: 1913 -LKREIENLKKQLEDLKNSGSQENVDEENNEM----------KEGADNLIDALQQSVDEK 1961
Query: 1637 H---EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLER 1467
+ ++LQ++ DD+ I+ L A +NE + + S ++ L E+E E
Sbjct: 1962 NKQIDDLQQKLDDQNREIELLKAKVEQIENINEEEDNEDIVVASTRDVELENVEEESPEE 2021
Query: 1466 SASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 1287
+ LA + +++L ++K + + +AE L + + + ++ D +
Sbjct: 2022 AKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEIEQIKSEKEDQDKEL-- 2079
Query: 1286 EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALE 1107
E+L E + ENG+ +++Q E + D++++ E++
Sbjct: 2080 EKLNNELTEALEKLENGKKKSSQEQNNEN------------EEDFVDDIEKLKEERE--- 2124
Query: 1106 KRCSDLEAKNASLTDNQEGHEAEIERKLEASNL-THNDELHKEKDDKESIMNDLDHVKAE 930
+L+++N SL NQ +++ LE NL ND+L+K +DKE N + +++E
Sbjct: 2125 ----NLKSENESL-KNQAPENEGLKKSLE--NLKKSNDDLNKSNEDKE---NKIKELESE 2174
Query: 929 RQVLESKVSDMETTYSTLNNE---LQQKMD--DNEAFLNERDGLEAVKQGLEKRVLDLEA 765
L+S+++++E + E L K+ +N ++ D + V R + ++
Sbjct: 2175 ISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDEDDITVV----GTRDISVDE 2230
Query: 764 TI---------HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 612
TI + E T +++ NE ++ + + EE DK K ++ +
Sbjct: 2231 TIPTDNETETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQL 2290
Query: 611 LS----EVTELQ---EDLNKE----SKEKQDLEKRVLELTSKLE 513
L+ EV L+ +DL E SK +L + EL ++E
Sbjct: 2291 LASKQGEVDALKSQNDDLKSENETLSKSNHELGTKTKELEEEIE 2334
Score = 67.4 bits (163), Expect = 6e-08
Identities = 125/631 (19%), Positives = 260/631 (41%), Gaps = 72/631 (11%)
Frame = -2
Query: 2192 NEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELL------NEKDDKKCIVEA 2031
NE D + ND A + LE + A T+N + ++ +D+K E+
Sbjct: 91 NEIDSLRAKYNDARAKSAAYE-LELQKAKQSLISRTINSNIHPLRSIGHDLEDEK---ES 146
Query: 2030 DKQALESKVSVFEAAIATLNDELLNEKDDKKC-------------------IVNDRNI-- 1914
++ S +S+++ + +LNDEL K + + + N+ N+
Sbjct: 147 LSDSISSTISIYDENLESLNDELSRLKQNSQNSELVKVLDNLTRTTDYVVNLENNENLER 206
Query: 1913 ---LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI------IKKALDK---RISDL 1770
+A +A+ L +LN EL+ K + + K+ + K I +
Sbjct: 207 YTTYDAQLRAISQAALRLSTKVNSLNAELQELKHSQSEMQIIVSQYKEVVPKISFHIETI 266
Query: 1769 KADAPQRD-QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALI 1593
+ D EDD N LI +N + N +ELQK K+ + L
Sbjct: 267 EKLVSINDTDEDDKNPLIFPQRLKRIRSEVQRLFDNNEKTN-----KELQKLKE-QLELY 320
Query: 1592 KDLVAAEPGKRTVNEIVS---HLESKSRSLKEHFLREE---------EDEVLERSASNLA 1449
+++ + K E+ S LE K+ L++ R + E E +E NL
Sbjct: 321 ENMKNGQSMKERQAELESLRLELEKKNAELEQLKARYQSKQDPQLLAEIERIENEVQNLK 380
Query: 1448 IMKAIREEELRK----------EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMD 1299
A RE +++ + + K ++EN E E + L+K + E + ++ +
Sbjct: 381 NKIADRESQIKALNLLIAQYQTDDEDKKEIIEN---LEKEIKDLKKQI-EDKDKEIEVLK 436
Query: 1298 A--IHEEELRKEKVDKSALTENGEGCE-AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1128
A EE+ +++ D+ + + + E + LE + L + L +
Sbjct: 437 AKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDDKKKNGV 496
Query: 1127 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDL 948
KQAL + +++E N + + ++ ++ + E+ +E N T N +L D+ + ++++L
Sbjct: 497 QMKQALASKDAEIEKLNEQIQELKDRNDKQ-EQNIEELN-TKNSDLQNSNDEYKKLIDEL 554
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDD-------NEAFLNERDGLEAVKQGLE 789
+ + +++ SD+ + +T + +K +D N+ E D L++ +GL+
Sbjct: 555 QNQLKDLAKNKAESSDLNNSENTKQDS--EKAEDENAETKSNKELQEESDKLKSENEGLK 612
Query: 788 KRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 609
K + +L+ + +DD N++ + + +I ELE
Sbjct: 613 KSLENLKKS----------NDDLNKSNEDK-ENKIKELE--------------------- 640
Query: 608 SEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
SE+++L+ ++N+ + +D ++ + L+SK+
Sbjct: 641 SEISKLKSEINELEQNNKDKDREIEILSSKV 671
>ref|XP_804789.1| R27-2 protein [Trypanosoma cruzi strain CL Brener]
gi|70867933|gb|EAN82938.1| R27-2 protein, putative
[Trypanosoma cruzi]
Length = 1597
Score = 132 bits (331), Expect = 2e-27
Identities = 143/626 (22%), Positives = 269/626 (42%), Gaps = 38/626 (6%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
EA + L + EA I L ++L + D + + + EAD + L ++A EA I
Sbjct: 561 EADIEKLTEDLAQREADIEKLAEDLAQREADIEKLTEELAQREADIEKLTEELAQREADI 620
Query: 2090 ATLNDELLNEKDDKKCIVE------ADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
L +EL + D + + E AD + L +++ EA I L ++L + D + +
Sbjct: 621 EKLTEELAQREADNEKLTEELAQREADNEKLTEELAQREADIEKLAEDLAQREADNEKLT 680
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1749
+ EA + L ++A EA L +EL +++ DN + ++ + + K
Sbjct: 681 EELAQREADNEKLAEELAQREADIEKLAEELAQREADNEKLAEELAQREADNEKLTEDLA 740
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1569
+E D L + ++ E +I L EEL + + D L +DLV E
Sbjct: 741 QREADNEKLTEDLAQREADIEKLTEELAQREADIEKLTEELVQREADIEKLTEDLVQREA 800
Query: 1568 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE---EELRKEKDGK 1398
+ E ++ E+ + L E + E D E+ +LA +A E E+L + +
Sbjct: 801 DIEKLTEDLAQREADNEKLAEDLAQREADN--EKLTEDLAQREADNEKLAEDLAQREADN 858
Query: 1397 SALVENGEGCEAEKQGLEKTVLERRASN------LDTMDAIHE---EELRKEKVDKSALT 1245
L E+ EA+ + L + + +R A N L +A +E EEL + + D LT
Sbjct: 859 EKLTEDLAQREADNEKLTEDLAQREADNEKLTEDLAQREADNEKLTEELVQREADNEKLT 918
Query: 1244 ENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1065
E EA+ + + ++ E I L + DL + A+ + L + + EA N LT
Sbjct: 919 EELAQREADNEKLTEDLVQREADIEKLTE----DLAQREADNEKLTEDLAQREADNEKLT 974
Query: 1064 DNQEGHEAEIER------KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
++ EA+IE+ + EA ++L + + D E + DL +A+ + L ++
Sbjct: 975 EDLVQREADIEKLTEDLVQREADIEKLTEDLVQREADIEKLTEDLAQREADNEKLTEDLA 1034
Query: 902 DMETTYSTLNNELQQKMDD----NEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 735
E L +L Q+ D E + +E + + L +R D E ++ +
Sbjct: 1035 QREADIEKLTEDLVQREADIEKLTEDLVQREADIEKLTEDLAQREADNEKLAEELAQREA 1094
Query: 734 KDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
++ EA+ + L + +++ E L ++ + DI ++ + + D K
Sbjct: 1095 DNEKLAEELVQREADNEKLAEELAQWEADNEKLAEELAQREADIEKLTEDLAQREADNEK 1154
Query: 572 ESKE----KQDLEKRVLELTSKLEKC 507
++E + D+EK ++L+ K +C
Sbjct: 1155 LAEELVQREADIEKLAVDLSQKEAEC 1180
Score = 95.1 bits (235), Expect = 3e-16
Identities = 149/645 (23%), Positives = 255/645 (39%), Gaps = 60/645 (9%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
EA + L ++ EA L +EL + D + + D EAD + L +A EA
Sbjct: 188 EADNEKLTEELAQREADNEKLAEELAQREADNEKLTEDLAQREADNEKLAEDLAQREADN 247
Query: 2090 ATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND---- 1923
L +EL EAD + L +++ EA I L ++L + D + + D
Sbjct: 248 EKLTEELAQR--------EADNEKLTEELAQREADIEKLAEDLAQREADNEKLAEDLAQR 299
Query: 1922 RNILEAAK--------------QALEYKVADLEAAKTTLNDELERKKDD----------N 1815
++E A+ + LE A E A T D LER+ D
Sbjct: 300 EAVIEGAEADASKTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEGE 359
Query: 1814 NAIIKKALDKRISDL--KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1641
NA + L + +++ +DA + + + L K++S +
Sbjct: 360 NAALAALLAAKKAEMVEASDAAGKSVRELESRLSAAVSEASHERAMAEKLISTTRGALTA 419
Query: 1640 LHEELQKEKDD--------KTALIKDLVA-AEPGKRTVNEIVSHLE---SKSRSL----- 1512
+ EE QK+ + + + +LVA E +NE +SH E S S +
Sbjct: 420 MVEENQKQVEQLRADHDQARATMQAELVAHREMRNARINERLSHPELCDSASPQVPPPNT 479
Query: 1511 ----------KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 1362
E F DE+ + N + +A+ + E EK L E EA
Sbjct: 480 DVPVAPEVVRSEPFYCVTLDELNKTGTLNEQLTRALAQREADNEK-----LTEELAQREA 534
Query: 1361 EKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLE 1182
+ + L + +++R A N EEL + D LTE+ EA+ + + + E
Sbjct: 535 DNEKLAEELVQREADNEKLT-----EELAHREADIEKLTEDLAQREADIEKLAEDLAQRE 589
Query: 1181 PTIPSLNDAL-QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASN 1011
I L + L QR+ D + + L +R +D+E L + +E E + EA N
Sbjct: 590 ADIEKLTEELAQREAD-IEKLTEELAQREADIEKLTEELAQREADNEKLTEELAQREADN 648
Query: 1010 LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 831
+EL + + D E + DL +A+ + L +++ E L EL Q+ D E
Sbjct: 649 EKLTEELAQREADIEKLAEDLAQREADNEKLTEELAQREADNEKLAEELAQREADIEKLA 708
Query: 830 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILT 651
E EA + L + + EA K +D EA+ + L + +++ E I LT
Sbjct: 709 EELAQREADNEKLAEELAQREAD----NEKLTEDLAQREADNEKLTEDLAQREADIEKLT 764
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
++ + DI E+ + + D+ K +++ E + +LT L
Sbjct: 765 EELAQREADIEKLTEELVQREADIEKLTEDLVQREADIEKLTEDL 809
Score = 62.8 bits (151), Expect = 1e-06
Identities = 113/620 (18%), Positives = 236/620 (38%), Gaps = 35/620 (5%)
Frame = -2
Query: 2264 AKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRN-----IVEADKQALENKVADFE 2100
A A V + E+ ++ E +E+ + +++ +VE +++ +E AD +
Sbjct: 4 ASDAAGKSVRELESRLSAAVSEASHERAMAEKLISTTRGALTAMVEENQKQVEQLRADHD 63
Query: 2099 ATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLND-----ELLNEKDDKKC 1935
AT+ EL+ ++ + + E S D E++ +
Sbjct: 64 QARATMQAELVAHREMRNARINERLSHPELCDSASPQVPPPNTDVPVAPEVVRSEPFYCV 123
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAP 1755
+++ N + L +A EA L +EL +++ DN + ++ + + + K
Sbjct: 124 TLDELNKTGTLNEQLTRALAQREADNEKLTEELAQREADNEKLAEELVQREADNEKLTEE 183
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
+E D L + ++ E + L E+L + + D L +DL
Sbjct: 184 LAQREADNEKLTEELAQREADNEKLAEELAQREADNEKLTEDLAQREADNEKLAEDLAQR 243
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 1395
E + E ++ E+ + L E + E D +E+ A +LA +A E+L ++ +
Sbjct: 244 EADNEKLTEELAQREADNEKLTEELAQREAD--IEKLAEDLAQREA-DNEKLAEDLAQRE 300
Query: 1394 ALVENGE--------GCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTEN 1239
A++E E G + + LE+ R + +D + E EL V AL
Sbjct: 301 AVIEGAEADASKTIEGVYSRCRELEELAARRELAATGDVDIL-ERELADALVQLKALEGE 359
Query: 1238 GEGCEAEKQGPEKTVLDLEP----TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
A + +++ ++ L L + E+ EK S +
Sbjct: 360 NAALAALLAAKKAEMVEASDAAGKSVRELESRLSAAVSEASHERAMAEKLISTTRGALTA 419
Query: 1070 LTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMND-LDHVK----AERQV----- 921
+ + + ++ + + T EL ++ + + +N+ L H + A QV
Sbjct: 420 MVEENQKQVEQLRADHDQARATMQAELVAHREMRNARINERLSHPELCDSASPQVPPPNT 479
Query: 920 ---LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 750
+ +V E Y +EL + NE EA + L + + EA
Sbjct: 480 DVPVAPEVVRSEPFYCVTLDELNKTGTLNEQLTRALAQREADNEKLTEELAQREAD---- 535
Query: 749 EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKE 570
K ++ EA+ + L + ++ E I +KL +D+ +++ +L EDL +
Sbjct: 536 NEKLAEELVQREADNEKLTEELAHREADI-------EKLTEDLAQREADIEKLAEDLAQR 588
Query: 569 SKEKQDLEKRVLELTSKLEK 510
+ + L + + + + +EK
Sbjct: 589 EADIEKLTEELAQREADIEK 608
>gb|EMD48416.1| viral Atype inclusion protein repeat-containing protein, partial
[Entamoeba histolytica KU27]
Length = 909
Score = 129 bits (323), Expect = 2e-26
Identities = 138/670 (20%), Positives = 295/670 (44%), Gaps = 36/670 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
KD+K+ + N+ N ++ + + N+ + I ++N+ N ++ K
Sbjct: 275 KDEKENISNELNQIKNERDNISNEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEK 334
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLN 2079
Q +E++ + +E+ +DK I N+ N ++ +KQ +EN+
Sbjct: 335 QKIEDEKAVIQQE---KENEITKLNEDKTVIENELNQIKTEKQEIENE------------ 379
Query: 2078 DELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILE--- 1908
LN+ D+K +E +K L +++S I+ LN+EL K +K+ ++N+ N ++
Sbjct: 380 ---LNQTKDEKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKENVLNELNQIKNEF 436
Query: 1907 -AAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA--LDKRISDLKADAPQRDQED 1737
+ K+ K +L+ + ELE+K ++ + + ++ + +S+ K + Q+ QE
Sbjct: 437 ASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQKKQE- 495
Query: 1736 DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRT 1557
I E L E+++K +++K+ LI +L G
Sbjct: 496 ------------------IITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISK 537
Query: 1556 VNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIR---EEELRKEKDGKSALV 1386
+NE ++ + + +++ EEE E LER + L +K + EEE K + K+ L
Sbjct: 538 LNEELTQTKQEKEEIQKAL--EEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQ 595
Query: 1385 ENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGP 1206
+ + + L +T E+ N + +++I EE+ R E+ + EN E E +
Sbjct: 596 QELNENKKIVEELTQTKQEKEEIN-NELNSIKEEKKRIEEEKNQIINENKEIKEENIKSI 654
Query: 1205 EKTVLDLEPTIPSLNDA-------------LQRDLDRVMAE-------KQALEKRCSDLE 1086
E+ ++ S+ + ++++ DRV++E + ++K+ +
Sbjct: 655 EEKTQEINSLTTSIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAH 714
Query: 1085 AKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIM---NDLDHVKAERQVLE 915
+ + + EG E E+ L + +T +E KEK E +M L + ++
Sbjct: 715 NRMTEMQKSFEGSENEMINSLN-NQITQLNE--KEKQMNEQVMALQTQLSQSNINLEEVK 771
Query: 914 SKVSDMETTYSTLNNEL----QQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE 747
+ + + Y+ +N E Q++ NE + + LE K+ L DL+ +
Sbjct: 772 KDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNKKELN----DLQTKYDNEI 827
Query: 746 MKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKES 567
++ K+ D + LK+ + LEE + + ++ KL+ +++ V++L E+L +
Sbjct: 828 LELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTK 887
Query: 566 KEKQDLEKRV 537
+EK+++ +
Sbjct: 888 QEKEEINNEL 897
Score = 116 bits (290), Expect = 1e-22
Identities = 138/623 (22%), Positives = 281/623 (45%), Gaps = 41/623 (6%)
Frame = -2
Query: 2210 LNDELLNEKDDKKCIVNDRN-IVEADKQALENKVADFEATIATL---------NDELLNE 2061
+N+EL + K++KK I ++N I+ +K+ E K E L N++L NE
Sbjct: 11 INNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE 70
Query: 2060 ----KDDKKCIVEADKQAL---ESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAA 1902
+ K I E +++ + +++ F+ L EL K++K+ N++N L
Sbjct: 71 INTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDV 130
Query: 1901 KQALEYKVADLEA-------AKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
K E ++ L+ KTT+ + L + ++ N + K+++ + + +KAD +
Sbjct: 131 KTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTK 190
Query: 1748 DQE------------DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
+ E +D + + S E + + EE Q+ +D+K
Sbjct: 191 ELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEK 250
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--LREEEDEVLERSASNLAIMKAIR 1431
LI D+ G +NE++ L+ + ++ ++ E D +
Sbjct: 251 AKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKT-------- 302
Query: 1430 EEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSA 1251
+EE++++++ L E EK+VL L+ ++ I EE+ + E D+ A
Sbjct: 303 KEEIKQKENETIQLNE------------EKSVL------LNELNQIKEEKQKIE--DEKA 342
Query: 1250 LTENGEGCEAEKQGPEKTVLDLE-PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 1074
+ + + E K +KTV++ E I + ++ +L++ EKQ +E + K+
Sbjct: 343 VIQQEKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIE------DEKSK 396
Query: 1073 SLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDME 894
+T+ G++ S L N+EL + K +KE+++N+L+ +K E + + + E
Sbjct: 397 LITELSNGNDG-------ISKL--NEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKE 447
Query: 893 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE 714
NN++QQ+++ NE LE K + +L T ++E K K +
Sbjct: 448 NELKDENNKVQQELEQKN---NEVSKLEEEKGNISN---ELSNTKQELEQK--KQEIITI 499
Query: 713 AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVL 534
+++ K+ +EL+E + + ++ KL+ +++ +++L E+L + +EK++++K +
Sbjct: 500 TQEKEEKE--NELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALE 557
Query: 533 ELTSKLEKCICGARDGLSTIKEA 465
E KLE+ L IKEA
Sbjct: 558 EEKEKLER----IETELKEIKEA 576
Score = 106 bits (264), Expect = 1e-19
Identities = 144/672 (21%), Positives = 294/672 (43%), Gaps = 68/672 (10%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEAAIATLNDEL--LNE-----KDDKKCIVNDRNIVEADKQALE 2121
N ++ KQ +E++ IA ND L LNE KD+K+ I N+ N ++ ++ +
Sbjct: 237 NKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNIS 296
Query: 2120 NKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNE---- 1953
N+ + I +E + ++K ++ Q E K + E A + E NE
Sbjct: 297 NEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKI-EDEKAVIQQEKENEITKL 355
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE----LERKKDDNNAIIKKALDK 1785
+DK I N+ N ++ KQ +E ++ + K + DE + + N+ I K L++
Sbjct: 356 NEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISK--LNE 413
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
++ K +++E+ +N L + + L+ + +EL+++ ++
Sbjct: 414 ELTQTK-----QEKENVLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEV 468
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFL-----REEEDEVLERSASNLAIMK 1440
+ L E K ++ +S+ + + K+ + +EE++ L+ + K
Sbjct: 469 SKL-------EEEKGNISNELSNTKQELEQKKQEIITITQEKEEKENELKEQVKKIEEEK 521
Query: 1439 AIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD 1260
+ EL DG S L E + EK+ ++K LE L+ + E EL++ K
Sbjct: 522 SKLITELSNGSDGISKLNEELTQTKQEKEEIQK-ALEEEKEKLERI----ETELKEIKEA 576
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSL------NDALQRDLDRVMAEKQALEKRC 1098
K L E EK ++ + + + + L + + +L+ + EK+ +E
Sbjct: 577 KQELEEEKNKTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIE--- 633
Query: 1097 SDLEAKNASLTDNQEGHEAEI----ERKLEASNLT---------------HNDELHKEKD 975
E KN + +N+E E I E+ E ++LT E+ KE+D
Sbjct: 634 ---EEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGERIEIEKERD 690
Query: 974 DKESIMNDL----DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER----- 822
S +ND+ + +K + + +++++M+ ++ NE+ +++ LNE+
Sbjct: 691 RVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMN 750
Query: 821 DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKA 642
+ + A++ L + ++LE D+ K NE EK +++ +++ E + ++
Sbjct: 751 EQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINE-EKDCVEQERNKINEEYKTVNEEL 809
Query: 641 KKLLKDIN----IWLSEVTELQED-------LNKESKEKQDLE---KRVLELTSKLEKCI 504
+K K++N + +E+ EL ++ +N +EK +LE K++ E SKL +
Sbjct: 810 EKNKKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITEL 869
Query: 503 CGARDGLSTIKE 468
DG+S + E
Sbjct: 870 SNGSDGVSKLNE 881
Score = 97.4 bits (241), Expect = 5e-17
Identities = 128/701 (18%), Positives = 296/701 (42%), Gaps = 58/701 (8%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
+++K ++N+ ++ K+ +E + + I +I +E
Sbjct: 26 EEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKN 85
Query: 2258 QAL----ENKVGDFEAAIATLNDELLNEKDDKKCIVNDRN---IVEADKQALENKVADFE 2100
Q + ++ F+ L EL K++K+ N++N V+ K+ NK+ + +
Sbjct: 86 QEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKENELNKLKEEK 145
Query: 2099 ATI---ATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
I T + LN+ ++K + +K++++ ++ +A +T E+ ++K +
Sbjct: 146 EQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEINKINEEKNQLQ 205
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1749
ND + ++ K+ ++ ++ ++ K+ +EL + K++ +
Sbjct: 206 NDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQV------------------- 246
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1569
ED+ LI ++N + L+E + K KD+K + +L
Sbjct: 247 --EDEKAKLITD--------------IANGNDGLTKLNEVIDKLKDEKENISNEL----- 285
Query: 1568 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE--EELRKEKDGKS 1395
+ ++ ++ KE ++++E+E ++ + ++ + + EE +K +D K+
Sbjct: 286 --NQIKNERDNISNEFNKTKEE-IKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKA 342
Query: 1394 ALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK-----------SAL 1248
+ + E E K +KTV+E + + T E EL + K +K + L
Sbjct: 343 VIQQEKEN-EITKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITEL 401
Query: 1247 TENGEGCEAEKQGPEKTVLDLEPTIPSLN-----------------DALQRDLDRVMAEK 1119
+ +G + +T + E + LN + L+ + ++V E
Sbjct: 402 SNGNDGISKLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKENELKDENNKVQQEL 461
Query: 1118 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
+ S LE + ++++ + E+E+K + ++ KE + KE + +
Sbjct: 462 EQKNNEVSKLEEEKGNISNELSNTKQELEQKKQEIITITQEKEEKENELKEQVKK----I 517
Query: 938 KAERQVLESKVSDMETTYSTLNNEL----QQKMDDNEAFLNERDGLEAVKQGLE-----K 786
+ E+ L +++S+ S LN EL Q+K + +A E++ LE ++ L+ K
Sbjct: 518 EEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAK 577
Query: 785 RVLDLEATIHDIEMKTGKDDDYNEAEK-----QTLKKRISELEEAISILTDKAKKLLKDI 621
+ L+ E IE KT + NE +K K+ E+ ++ + ++ K++ ++
Sbjct: 578 QELEEEKN-KTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEK 636
Query: 620 NIWLSEVTELQED----LNKESKEKQDLEKRVLELTSKLEK 510
N ++E E++E+ + ++++E L + EL +LE+
Sbjct: 637 NQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEE 677
Score = 83.2 bits (204), Expect = 1e-12
Identities = 90/434 (20%), Positives = 195/434 (44%), Gaps = 47/434 (10%)
Frame = -2
Query: 1628 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLA 1449
L + K +K + +L + + K+ + E + + ++++ +KE + EE+
Sbjct: 1 LTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEE----------- 49
Query: 1448 IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE 1269
K +E+ KEK+G + L + + +E+ E N + EE+ +
Sbjct: 50 --KKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQ 107
Query: 1268 KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
K + + + E + E EK ++D++ + + L+ + +++ EK +E + +
Sbjct: 108 K-ELNQIKEEKQKTENEK----NELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQI 162
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESK 909
+ LT+ +E + E++ ++A N T E++K ++K + ND D V+ E++ ++ +
Sbjct: 163 VEEKNKLTEEKESIKQELD-SIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKE 221
Query: 908 VSDMETTYSTLNNEL------QQKMDDNEAFL-----NERDGLEAVKQGLEKRVLDLEAT 762
++ ++ S EL +Q+++D +A L N DGL + + ++K + E
Sbjct: 222 LNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENI 281
Query: 761 IHDI-EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL-------- 609
+++ ++K +D+ NE K K+ I + E L ++ LL ++N
Sbjct: 282 SNELNQIKNERDNISNEFNK--TKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIED 339
Query: 608 ----------SEVTELQED-------LNKESKEKQDLE----------KRVLELTSKLEK 510
+E+T+L ED LN+ EKQ++E +++ + SKL
Sbjct: 340 EKAVIQQEKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLIT 399
Query: 509 CICGARDGLSTIKE 468
+ DG+S + E
Sbjct: 400 ELSNGNDGISKLNE 413
Score = 72.8 bits (177), Expect = 1e-09
Identities = 124/596 (20%), Positives = 244/596 (40%), Gaps = 89/596 (14%)
Frame = -2
Query: 2435 DDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQ 2256
+DK + N+ N ++ KQ +EN++ + +++ +E K
Sbjct: 357 EDKTVIENELNQIKTEKQEIENELNQTK---------------------DEKQKIEDEKS 395
Query: 2255 ALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLND 2076
L ++ + I+ LN+EL K +K+ ++N+ N ++N+ A F+ N
Sbjct: 396 KLITELSNGNDGISKLNEELTQTKQEKENVLNELN-------QIKNEFASFKEQ----NT 444
Query: 2075 ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDD----KKCIVNDRNILE 1908
+ NE D+ V+ + + ++VS E +++EL N K + K+ I+ E
Sbjct: 445 QKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQKKQEIITITQEKE 504
Query: 1907 AAKQALEYKVADLEAAKTTL--------------NDELERKKDDNNAIIK------KALD 1788
+ L+ +V +E K+ L N+EL + K + I K + L+
Sbjct: 505 EKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKEKLE 564
Query: 1787 KRISDLKA-DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD 1611
+ ++LK +++ E++ N I KIV EEL + K
Sbjct: 565 RIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIV-----------EELTQTKQ 613
Query: 1610 DKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI--MKA 1437
+K + +L + + K+ + E + + ++++ +KE ++ E++ E ++ +I +K
Sbjct: 614 EKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKG 673
Query: 1436 IREE------ELRKEKD--------------GKSALVENGEGCEAEKQ----GLEKTVLE 1329
EE E+ KE+D G VE E Q G E ++
Sbjct: 674 RLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMIN 733
Query: 1328 RRASNLDTMDA--------------------IHEEELRKEKVDK----SALTENGEGCEA 1221
+ + ++ I+ EE++K+ ++ + + E + E
Sbjct: 734 SLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQ 793
Query: 1220 EKQGPE---KTVLD-LEPTIPSLNDALQRDLDRVMAE----KQALEKRCSDLEAKNASLT 1065
E+ KTV + LE LND LQ D + E K L ++L+ + +L
Sbjct: 794 ERNKINEEYKTVNEELEKNKKELND-LQTKYDNEILELNKNKDELNSLINNLKEEKTNLE 852
Query: 1064 DNQEGHEAEIERKL-EASNLTH-----NDELHKEKDDKESIMNDLDHVKAERQVLE 915
+ + E E + + E SN + N+EL + K +KE I N+L+ +K E+ ++
Sbjct: 853 EQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKNQIK 908
>ref|XP_808187.1| myosin heavy chain [Trypanosoma cruzi strain CL Brener]
gi|70872338|gb|EAN86336.1| myosin heavy chain, putative
[Trypanosoma cruzi]
Length = 3543
Score = 127 bits (318), Expect = 6e-26
Identities = 138/610 (22%), Positives = 260/610 (42%), Gaps = 23/610 (3%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
EA + L + EA L ++L + D + + D EAD + L +A EA I
Sbjct: 2493 EADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADI 2552
Query: 2090 ATLNDELLNEKDDKKCIVE------ADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
L ++L + D + + E AD + L +++ EA I L ++L + D + +
Sbjct: 2553 EKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADNEKLA 2612
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1749
+ EA + L +A EA L DEL +++ DN + + + + K
Sbjct: 2613 EELAQREADIEKLAEDLAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLA 2672
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1569
+E D L+ ++ E +I L +EL + + D L +DL E
Sbjct: 2673 QREADNEKLVEE--------------LAQREADIEKLTDELAQREADNEKLAEDLAQREA 2718
Query: 1568 GKRTVNEIVSHLESKSRSLKEHFLREEED--EVLERSASNLAIMKAIREEELRKEKDGKS 1395
+ E ++ E+ L + + E D +++E A A ++ + +E ++E D +
Sbjct: 2719 DNEKLAEDLAQREADIEKLTDELAQREADNEKLVEELAQREADIEKLTDELAQREADNEK 2778
Query: 1394 ALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE---------EELRKEKVDKSALTE 1242
L E+ EA+ + L + + +R A N + + + E+L + + D L E
Sbjct: 2779 -LAEDLAQREADNEKLTEDLAQREADNEKLAEDLAQREADIEKLAEDLAQREADNEKLAE 2837
Query: 1241 NGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD 1062
+ EA+ + + + E I + L DL + A+ + L + + EA N L +
Sbjct: 2838 DLAQREADNEKLAEELAQREADI----EKLAEDLAQREADNEKLAEELAQREADNEKLAE 2893
Query: 1061 NQEGHEAEIER------KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSD 900
+ EA+ E+ + EA N +EL + + D E + DL +A+ + L ++
Sbjct: 2894 DLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADNEKLAEDLAQ 2953
Query: 899 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY 720
E L +EL Q+ DNE + EA + L + + EA DIE K +D
Sbjct: 2954 READIEKLTDELAQREADNEKLAEDLAQREADNEKLAEELAQREA---DIE-KLAEDLAQ 3009
Query: 719 NEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
EA+ + L +++ E +KL +D+ ++ +L +DL + + + L +
Sbjct: 3010 READIEKLTDELAQREA-------DNEKLAEDLAQREADNEKLTDDLAQREADNEKLVEE 3062
Query: 539 VLELTSKLEK 510
+ + + +EK
Sbjct: 3063 LAQREADIEK 3072
Score = 120 bits (301), Expect = 6e-24
Identities = 145/611 (23%), Positives = 256/611 (41%), Gaps = 9/611 (1%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
EA + L ++ EA I L DEL + D + + D EAD + L +A EA I
Sbjct: 2675 EADNEKLVEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADI 2734
Query: 2090 ATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
L DEL EAD + L +++ EA I L DEL + D + + D
Sbjct: 2735 EKLTDELAQR--------EADNEKLVEELAQREADIEKLTDELAQREADNEKLAEDLAQR 2786
Query: 1910 EAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISD--LKADAPQRDQED 1737
EA + L +A EA L ++L +++ D + + + + L D QR+ ++
Sbjct: 2787 EADNEKLTEDLAQREADNEKLAEDLAQREADIEKLAEDLAQREADNEKLAEDLAQREADN 2846
Query: 1736 DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRT 1557
+ A + ++ E +I L E+L + + D L ++L E
Sbjct: 2847 EKLA----------------EELAQREADIEKLAEDLAQREADNEKLAEELAQREADNEK 2890
Query: 1556 VNEIVSHLESKSRSLKEHFLREEED--EVLERSASNLAIMKAIREEELRKEKDGKSALVE 1383
+ E ++ E+ + L E + E D ++ E A A ++ + E+ ++E D + L E
Sbjct: 2891 LAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADNEK-LAE 2949
Query: 1382 NGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE 1203
+ EA+ + L + +R A N E+L + + D L E EA+ +
Sbjct: 2950 DLAQREADIEKLTDELAQREADNEKL-----AEDLAQREADNEKLAEELAQREADIEKLA 3004
Query: 1202 KTVLDLEPTIPSLNDAL-QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK 1026
+ + E I L D L QR+ A+ + L + + EA N LTD+ EA+ E+
Sbjct: 3005 EDLAQREADIEKLTDELAQRE-----ADNEKLAEDLAQREADNEKLTDDLAQREADNEKL 3059
Query: 1025 LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDD 846
+E EL + + D E + ++L +A+ + L ++ E L EL Q+ D
Sbjct: 3060 VE--------ELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLVEELAQREAD 3111
Query: 845 NEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEA 666
NE + EA K V +L+ + ++ + ++ +E A
Sbjct: 3112 NEKLAEDLVRREA---DCHKLVAELDVIESKLNSAMSGLHVFSSGDGGVIEMLEGYMERA 3168
Query: 665 ISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICG---- 498
S+++ K L+ +++ E+ L+ D E +DL R +EL + + G
Sbjct: 3169 -SLVSGAEKDALERLSLSNKELAMLRSDFLAE----RDLMSREIELEKAEKARLLGELEV 3223
Query: 497 ARDGLSTIKEA 465
+ L T+K A
Sbjct: 3224 TQRNLETLKNA 3234
Score = 118 bits (296), Expect = 2e-23
Identities = 150/669 (22%), Positives = 269/669 (40%), Gaps = 82/669 (12%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
EA + L ++ EA I L DEL + D + + D EAD + L ++A EA I
Sbjct: 744 EADNEKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLVEELAQREADI 803
Query: 2090 ATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
L DEL EAD + L +++ EA I L DEL + D + + D
Sbjct: 804 EKLTDELAQR--------EADNEKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQR 855
Query: 1910 EAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDM 1731
EA + L +A EA L ++L +++ DN + + + + K +E D
Sbjct: 856 EADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADN 915
Query: 1730 NALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL----VAAEPGK 1563
L ++ E + L E+L + + D L ++L E +
Sbjct: 916 EKLAEDLAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAE 975
Query: 1562 RTVNEIVSHLESKSRSLKEHFLREE-----EDEVLERSASN--------------LAIMK 1440
++ + + S+ R L+E R E + ++LER ++ LA +
Sbjct: 976 ADASKTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAALL 1035
Query: 1439 AIREEELRKEKDGKSALVE-------------NGEGCEAEK-----QGLEKTVLERRASN 1314
A ++ E+ + D V + E AEK +G ++E
Sbjct: 1036 AAKKAEMVEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTAMVEENQKQ 1095
Query: 1313 LDTMDAIHEE-------------ELRKEKVDKSALTENGEGCE--AEKQGPEKTVLDLEP 1179
++ + A H++ E+R ++++ + E C+ + + P T + + P
Sbjct: 1096 VEQLRADHDQARATMQAELVAHREMRNARINER--LSHPELCDSASPQMPPPNTEVPVAP 1153
Query: 1178 -----------TIPSLN--DALQRDLDRVMAEKQA-LEKRCSDL---EAKNASLTDNQEG 1050
TI LN L L R +A+++A EK DL EA LTD
Sbjct: 1154 EIVRSEPLYSVTIDELNKTTTLNEQLTRALAQREADNEKLAEDLAQREADIEKLTDELAQ 1213
Query: 1049 HEAEIER------KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETT 888
EA+IE+ + EA N DEL + + D E + DL +A+ + L ++ E
Sbjct: 1214 READIEKLTDELAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREAD 1273
Query: 887 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 708
L +L Q+ DNE + EA + L + + EA + + + + NE
Sbjct: 1274 NEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADNEKLTEELAQREADNEKL 1333
Query: 707 KQTLKKRISELEEAISILTDKA---KKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 537
+ L +R ++ E+ L + +KL +++ ++ +L EDL + + + L + +
Sbjct: 1334 AEDLAQREADNEKLAEDLAQREADNEKLTEELAQREADNEKLAEDLAQREADNEKLTEEL 1393
Query: 536 LELTSKLEK 510
+ + +EK
Sbjct: 1394 AQREADIEK 1402
Score = 114 bits (286), Expect = 3e-22
Identities = 139/612 (22%), Positives = 252/612 (41%), Gaps = 12/612 (1%)
Frame = -2
Query: 2213 TLNDELLN-----EKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDK 2049
TLN++L E D++K + D EAD + L +++A EA I L DEL
Sbjct: 1174 TLNEQLTRALAQREADNEK-LAEDLAQREADIEKLTDELAQREADIEKLTDELAQR---- 1228
Query: 2048 KCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL 1869
EAD + L +++ EA L ++L + D + + D EA + L +A
Sbjct: 1229 ----EADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQR 1284
Query: 1868 EAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXX 1689
EA L ++L +++ DN + ++ + + K +E D L
Sbjct: 1285 EADNEKLAEDLAQREADNEKLAEELAQREADNEKLTEELAQREADNEKLAEDLAQREADN 1344
Query: 1688 XXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK 1509
+ ++ E + L EEL + + D L +DL E + E ++ E+ L
Sbjct: 1345 EKLAEDLAQREADNEKLTEELAQREADNEKLAEDLAQREADNEKLTEELAQREADIEKLA 1404
Query: 1508 EHFLREEEDEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKT 1338
E + E D E+ A LA +A E EEL + + L E EA+ + L +
Sbjct: 1405 EDLAQREADN--EKLAEELAQREADNEKLAEELAQREADNEKLAEELAQREADNEKLAEE 1462
Query: 1337 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 1158
+ +R A N E+L + + D LTE+ EA+ + + + E N+
Sbjct: 1463 LAQREADNEKLA-----EDLAQREADNEKLTEDLAQREADNEKLAEELAQREAD----NE 1513
Query: 1157 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEK 978
L +L + A+ + L + + EA N L ++ EA+ E+ E EL + +
Sbjct: 1514 KLAEELVQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAE--------ELAQRE 1565
Query: 977 DDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
D E + +L +A+ + L +++ E L +L Q+ DNE E EAV +
Sbjct: 1566 ADNEKLTEELAQREADNEKLTEELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIE 1625
Query: 797 GLE----KRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL 630
G E K + + + ++E + + + L++ +++ + L + L
Sbjct: 1626 GAEADASKTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALA 1685
Query: 629 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDC 450
+ ++ E+ E + + ++LE R+ S+ A +ST + A +
Sbjct: 1686 A---LLAAKKAEMVEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTA-- 1740
Query: 449 MVPDNWVPFEDL 414
MV +N E L
Sbjct: 1741 MVEENQKQVEQL 1752
Score = 101 bits (251), Expect = 4e-18
Identities = 144/671 (21%), Positives = 258/671 (38%), Gaps = 86/671 (12%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
EA + L ++ EA I L DEL + D + + D EAD + L +A EA
Sbjct: 161 EADNEKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADN 220
Query: 2090 ATLNDELLNEKDDKKCIVE------ADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
L ++L + D + + E AD + L ++ EA L DEL + D + +
Sbjct: 221 EKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLTDELAQREADNEKLA 280
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISD--LKADAP 1755
D EA + L ++A EA L DEL +++ DN + + + + L D
Sbjct: 281 EDLAQREADNEKLAEELAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLTEDLA 340
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
QR+ +++ A + ++ E + L +EL + + D L +DL
Sbjct: 341 QREADNEKLA----------------EDLAQREADNEKLTDELAQREADNEKLAEDLAQR 384
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE---EELRKEKD 1404
E + E ++ E+ + L E + E D E+ A +LA +A E EEL + +
Sbjct: 385 EADNEKLTEDLAQREADNEKLAEELAQREADN--EKLAEDLAQREADNEKLVEELAQREA 442
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE 1224
L E EA+ + L + + +R A N + + + E E + A ++ EG
Sbjct: 443 DNEKLAEELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADA-SKTIEGVY 501
Query: 1223 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALE------------KRCSDLEAK 1080
+ + E+ E D L+R+L + + +ALE K+ +EA
Sbjct: 502 SRCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAALLAAKKAEMVEAS 561
Query: 1079 NA------------SLTDNQEGHEAEIERKLEAS-----------NLTHNDELHKEKDDK 969
+A S ++ HE + KL ++ N ++L + D
Sbjct: 562 DAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTAMVEENQKQVEQLRADHDQA 621
Query: 968 ESIMNDLDHVKAERQVLESKVSD------------------------------METTYST 879
+ M + A R++ +++++ E YS
Sbjct: 622 RATMQ--AELVAHREMRNARINERLSHPELCDSASPQMPPPNTEVPVAPEIVRSEPLYSV 679
Query: 878 LNNELQQKMDDNE----AFLNERDGLEAVKQGLEKRVLDLEATIHDIEM------KTGKD 729
+EL + NE A E + + L +R D E D+ K +D
Sbjct: 680 TIDELNKTTTLNEQLTRALAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAED 739
Query: 728 DDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDL 549
EA+ + L + +++ E I LTD+ + D ++ + + D K +E
Sbjct: 740 LAQREADNEKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLVEELAQR 799
Query: 548 EKRVLELTSKL 516
E + +LT +L
Sbjct: 800 EADIEKLTDEL 810
Score = 96.3 bits (238), Expect = 1e-16
Identities = 135/650 (20%), Positives = 265/650 (40%), Gaps = 29/650 (4%)
Frame = -2
Query: 2276 ILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR--NIVEADKQALENKVADF 2103
++E ++ +E D + A AT+ EL+ ++ + +N+R + D + + +
Sbjct: 6 MVEENQKQVEQLCADHDQARATMQAELVAHREMRNARINERLSHPELCDSASPQMPPPNT 65
Query: 2102 EATIA---TLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCI 1932
E +A ++ L + D+ + L ++ EA L ++L + D + +
Sbjct: 66 EVPVAPEIVRSEPLYSVTIDELNKTTTLNEQLTRALAQREADNEKLAEDLAQREADNEKL 125
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--ISDLKADA 1758
D EA + L +A EA L ++L +++ DN + ++ + I L +
Sbjct: 126 AEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLTDEL 185
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
QR+ +++ L E+L + + D L +DL
Sbjct: 186 AQREADNEK------------------------------LAEDLAQREADNEKLAEDLAQ 215
Query: 1577 AEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE---EELRKEK 1407
E + E ++ E+ + L E + E D E+ A +LA +A E +EL + +
Sbjct: 216 READNEKLAEDLAQREADNEKLAEDLAQREADN--EKLAEDLAQREADNEKLTDELAQRE 273
Query: 1406 DGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKV---------DKS 1254
L E+ EA+ + L + + +R A N D + + E EK+ D
Sbjct: 274 ADNEKLAEDLAQREADNEKLAEELAQREADNEKLTDELAQREADNEKLAEDLAQREADNE 333
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 1074
LTE+ EA+ EK DL N+ L +L + A+ + L + + EA N
Sbjct: 334 KLTEDLAQREADN---EKLAEDLAQREAD-NEKLTDELAQREADNEKLAEDLAQREADNE 389
Query: 1073 SLTDNQEGHEAEIER------KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLES 912
LT++ EA+ E+ + EA N ++L + + D E ++ +L +A+ + L
Sbjct: 390 KLTEDLAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLVEELAQREADNEKLAE 449
Query: 911 KVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE----KRVLDLEATIHDIEM 744
+++ E L +L Q+ DNE E EAV +G E K + + + ++E
Sbjct: 450 ELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKTIEGVYSRCRELEE 509
Query: 743 KTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 564
+ + + L++ +++ + L + L + ++ E+ E + +
Sbjct: 510 LAARRELAATGDVDILERELADALVQLKALEGENAALAA---LLAAKKAEMVEASDAAGR 566
Query: 563 EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDL 414
++LE R+ S+ A +ST + A + MV +N E L
Sbjct: 567 SVRELESRLSAAVSEASHERAMAEKLISTTRGALTA--MVEENQKQVEQL 614
Score = 96.3 bits (238), Expect = 1e-16
Identities = 143/722 (19%), Positives = 274/722 (37%), Gaps = 83/722 (11%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
D + + D EA + L ++A E + + D EA +
Sbjct: 1954 DNEKLAEDLAQREADNEKLVEELAQREADNEKLTDELAQREADNEKLAEDLAQREADNEK 2013
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
L + EA L ++L + D + + D EAD + L +A EA L +
Sbjct: 2014 LAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEN 2073
Query: 2072 LLNEKDDKKCIVE------ADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
L + D + + E AD + L ++ EA I L DEL + D + + D
Sbjct: 2074 LAQREADNEKLAEDLAQREADNEKLAENLAQREADIEKLTDELAQREADNEKLAEDLAQR 2133
Query: 1910 EAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISD--LKADAPQRDQED 1737
EA + L +A EA L +EL +++ DN + + + + L D QR+ ++
Sbjct: 2134 EADNEKLAEDLAQREADNEKLVEELAQREADNEKLTDELAQREADNEKLAEDLAQREADN 2193
Query: 1736 DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL----VAAEP 1569
+ L E+L + + D L ++L E
Sbjct: 2194 EK------------------------------LAEDLAQREADNEKLAEELAQREAVIEG 2223
Query: 1568 GKRTVNEIVSHLESKSRSLKEHFLREE-----EDEVLERSASN--------------LAI 1446
+ ++ + + S+ R L+E R E + ++LER ++ LA
Sbjct: 2224 AEADASKTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAA 2283
Query: 1445 MKAIREEELRKEKDGKSALVE-------------NGEGCEAEK-----QGLEKTVLERRA 1320
+ A ++ E+ + D V + E AEK +G ++E
Sbjct: 2284 LLAAKKAEMVEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTAMVEENQ 2343
Query: 1319 SNLDTMDAIHEE-------------ELRKEKVDKSALTENGEGCE--AEKQGPEKTVLDL 1185
++ + A H++ E+R ++++ + E C+ + + P T + +
Sbjct: 2344 KQVEQLRADHDQARATMQAELVAHREMRNARINER--LSHPELCDSASPQMPPPNTEVPV 2401
Query: 1184 EPTI---PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER----- 1029
P I L +L++ + L + + EA N L ++ EA+IE+
Sbjct: 2402 APEIVRSEPLYSVTIDELNKTTTLNEQLTRALAQREADNEKLAEDLAQREADIEKLAEDL 2461
Query: 1028 -KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKM 852
+ EA N ++L + + D E + +L +A+ + L ++ E L +L Q+
Sbjct: 2462 AQREADNEKLAEDLAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLAEDLAQRE 2521
Query: 851 DDNEAFLNERDGLEA----VKQGLEKRVLDLEATIHDIEM------KTGKDDDYNEAEKQ 702
DNE + EA + + L +R D+E D+ K +D EA+ +
Sbjct: 2522 ADNEKLAEDLAQREADNEKLAEDLAQREADIEKLAEDLAQREADNEKLAEDLAQREADNE 2581
Query: 701 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 522
L + +++ E I L + + D E+ + + D+ K +++ E + +LT
Sbjct: 2582 KLAEELAQREADIEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADIEKLTD 2641
Query: 521 KL 516
+L
Sbjct: 2642 EL 2643
Score = 91.7 bits (226), Expect = 3e-15
Identities = 123/566 (21%), Positives = 228/566 (40%), Gaps = 16/566 (2%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
EA + L + EA L ++L + D + + D EAD + L +A EA
Sbjct: 1840 EADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADN 1899
Query: 2090 ATLNDELLNEKDDKKCIVE------ADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
L ++L + D + + E AD + L ++ EA L +EL + D + +
Sbjct: 1900 EKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLVEELAQREADNEKLA 1959
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISD--LKADAP 1755
D EA + L ++A EA L DEL +++ DN + + + + L D
Sbjct: 1960 EDLAQREADNEKLVEELAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLA 2019
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
QR+ +++ A + ++ E + L E+L + + D L +DL
Sbjct: 2020 QREADNEKLA----------------EDLAQREADNEKLAEDLAQREADNEKLAEDLAQR 2063
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE---EELRKEKD 1404
E + E ++ E+ + L E + E D E+ A NLA +A E +EL + +
Sbjct: 2064 EADNEKLAENLAQREADNEKLAEDLAQREADN--EKLAENLAQREADIEKLTDELAQREA 2121
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE 1224
L E+ EA+ + L + + +R A N + EEL + + D LT+ E
Sbjct: 2122 DNEKLAEDLAQREADNEKLAEDLAQREADNEKLV-----EELAQREADNEKLTDELAQRE 2176
Query: 1223 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE 1044
A+ N+ L DL + A+ + L + + EA N L + E
Sbjct: 2177 AD------------------NEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQRE 2218
Query: 1043 AEIE-RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNE 867
A IE + +AS K + S +L+ + A R++ + D+ L E
Sbjct: 2219 AVIEGAEADAS---------KTIEGVYSRCRELEELAARRELAATGDVDI------LERE 2263
Query: 866 LQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIEMKTGKDDDYNEAEKQT 699
L + +A E L A+ + +++ ++ ++E + E+
Sbjct: 2264 LADALVQLKALEGENAALAALLAAKKAEMVEASDAAGRSVRELESRLSAAVSEASHERAM 2323
Query: 698 LKKRISELEEAISILTDKAKKLLKDI 621
+K IS A++ + ++ +K ++ +
Sbjct: 2324 AEKLISTTRGALTAMVEENQKQVEQL 2349
Score = 91.3 bits (225), Expect = 4e-15
Identities = 133/637 (20%), Positives = 250/637 (39%), Gaps = 50/637 (7%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
EA + L + EA L ++L + D + + D EAD + L ++A EA I
Sbjct: 702 EADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADI 761
Query: 2090 ATLNDELLNEKDDKKCIV------EADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
L DEL + D + + EAD + L +++ EA I L DEL + D + +
Sbjct: 762 EKLTDELAQREADNEKLAEDLAQREADNEKLVEELAQREADIEKLTDELAQREADNEKLA 821
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1749
+ EA + L ++A EA L ++L +++ DN + + + + K
Sbjct: 822 EELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLA 881
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1569
+E D L + ++ E + L E+L + + D L +L E
Sbjct: 882 QREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLTDELAQREA 941
Query: 1568 GKRTVNEIVSHLESKSRSLKEHFLREE---EDEVLERSASNLAIMKAIRE-EELRK---- 1413
+ E ++ E+ + L E + E E + S + + RE EEL
Sbjct: 942 DNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKTIEGVYSRCRELEELAARREL 1001
Query: 1412 ---------EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD 1260
E++ ALV+ + E E L + ++A ++ DA E
Sbjct: 1002 AATGDVDILERELADALVQL-KALEGENAALAALLAAKKAEMVEASDAAGRSVRELESRL 1060
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAE-KQALEKRCSDL-- 1089
+A++E E+ EK + + ++ + Q+ ++++ A+ QA ++L
Sbjct: 1061 SAAVSE----ASHERAMAEKLISTTRGALTAMVEENQKQVEQLRADHDQARATMQAELVA 1116
Query: 1088 --EAKNASLTDNQEGHE-------------------AEIERKLEASNLTHNDELHKEKDD 972
E +NA + + E EI R ++T DEL+K
Sbjct: 1117 HREMRNARINERLSHPELCDSASPQMPPPNTEVPVAPEIVRSEPLYSVT-IDELNKTTTL 1175
Query: 971 KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 792
E + L +A+ + L ++ E L +EL Q+ D E +E EA + L
Sbjct: 1176 NEQLTRALAQREADNEKLAEDLAQREADIEKLTDELAQREADIEKLTDELAQREADNEKL 1235
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKA---KKLLKDI 621
+ EA + + + NE + L +R ++ E+ L + +KL +D+
Sbjct: 1236 TDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDL 1295
Query: 620 NIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
++ +L E+L + + + L + + + + EK
Sbjct: 1296 AQREADNEKLAEELAQREADNEKLTEELAQREADNEK 1332
Score = 80.9 bits (198), Expect = 5e-12
Identities = 135/663 (20%), Positives = 255/663 (38%), Gaps = 77/663 (11%)
Frame = -2
Query: 2276 ILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR------------------- 2154
++E ++ +E D + A AT+ EL+ ++ + +N+R
Sbjct: 603 MVEENQKQVEQLRADHDQARATMQAELVAHREMRNARINERLSHPELCDSASPQMPPPNT 662
Query: 2153 ------NIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFE 1992
IV ++ L + D TLN++L + EAD + L ++ E
Sbjct: 663 EVPVAPEIVRSEP--LYSVTIDELNKTTTLNEQLTRALAQR----EADNEKLAEDLAQRE 716
Query: 1991 AAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNN 1812
A L ++L + D + + D EA + L ++A EA L DEL +++ DN
Sbjct: 717 ADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLTDELAQREADNE 776
Query: 1811 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
+ + + + K +E D+ L + ++ E +I L +
Sbjct: 777 KLAEDLAQREADNEKLVEELAQREADIEKLTDELAQREADNEKLAEELAQREADIEKLTD 836
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 1452
EL + + D L +DL E + E ++ E+ + L E + E D E+ A +L
Sbjct: 837 ELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADN--EKLAEDL 894
Query: 1451 AIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEE 1281
A +A E E+L + + L E+ EA+ + L + +R A N + + + E
Sbjct: 895 AQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLTDELAQREADNEKLAEDLAQRE 954
Query: 1280 LRKEKVDKSALTENG--EGCEAEK----QGPEKTVLDLEPTIPSLN-------DALQRDL 1140
EK+ + EG EA+ +G +LE D L+R+L
Sbjct: 955 ADNEKLAEELAQREAVIEGAEADASKTIEGVYSRCRELEELAARRELAATGDVDILEREL 1014
Query: 1139 DRVMAEKQALEKR----CSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 972
+ + +ALE + L AK A + + + + R+LE+ E E+
Sbjct: 1015 ADALVQLKALEGENAALAALLAAKKAEMVEASDAAGRSV-RELESRLSAAVSEASHERAM 1073
Query: 971 KESIMND-----LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER----- 822
E +++ V+ ++ +E +D + +T+ EL + A +NER
Sbjct: 1074 AEKLISTTRGALTAMVEENQKQVEQLRADHDQARATMQAELVAHREMRNARINERLSHPE 1133
Query: 821 ------------DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD------YNEAEKQTL 696
+ V + + TI ++ T ++ EA+ + L
Sbjct: 1134 LCDSASPQMPPPNTEVPVAPEIVRSEPLYSVTIDELNKTTTLNEQLTRALAQREADNEKL 1193
Query: 695 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE----KQDLEKRVLEL 528
+ +++ E I LTD+ + DI E+ + + D K + E + D EK +L
Sbjct: 1194 AEDLAQREADIEKLTDELAQREADIEKLTDELAQREADNEKLTDELAQREADNEKLAEDL 1253
Query: 527 TSK 519
+
Sbjct: 1254 AQR 1256
>ref|XP_809970.1| hypothetical protein [Trypanosoma cruzi strain CL Brener]
gi|70874433|gb|EAN88119.1| hypothetical protein,
conserved [Trypanosoma cruzi]
Length = 2493
Score = 125 bits (313), Expect = 2e-25
Identities = 182/745 (24%), Positives = 310/745 (41%), Gaps = 48/745 (6%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAG---KQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNIL 2271
E+DD +NDR LE K ALE++ ++ A+A ++ +
Sbjct: 1212 ERDDALAALNDR--LEEHSREKSALESRTSESVDALAAMERQPQERDDALAALNDRLEEY 1269
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEA-DKQALENKVADFEAT 2094
K ALE++ + A+ TL +L E+DD + DR + +K ALE++ ++
Sbjct: 1270 SREKSALESRTSESVDAVVTLRRQL-QERDDALAALKDRLEEHSREKSALESRTSESVDA 1328
Query: 2093 IATLNDELLNEKDDKKCIVE-------ADKQALESKVSVFEAAIATLNDELLNEKDDKKC 1935
+ TL +L E+DD ++ +K ALES+ S A+A + +L E+DD
Sbjct: 1329 VVTLRRQL-QERDDALAALKDRLEEYSREKSALESRTSESVGALAAMERQL-QERDDALA 1386
Query: 1934 IVNDRNILEA---AKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKA 1764
+NDR LE K ALE + ++ A TL +L+ ++DD A +K L++ + K+
Sbjct: 1387 ALNDR--LEEYGREKSALESRTSESVDAVVTLRRQLQ-ERDDALAALKDRLEEYGRE-KS 1442
Query: 1763 DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
R E V+ L E +E+DD A +KD
Sbjct: 1443 ALESRTSES---------------------------VDALAAMERQLQERDDALAALKD- 1474
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
L+EH E LE S A E +L++ D
Sbjct: 1475 ----------------------RLEEH---SREKSALESRTSESVDALAAMERQLQERDD 1509
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE 1224
+AL + E+ EK+ LE R S A E +L++ +AL + E
Sbjct: 1510 ALAALND-----RLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYS 1564
Query: 1223 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE 1044
EK E + + +L LQ D + A K LE+ + A S T G
Sbjct: 1565 REKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALE-SRTSESVGAL 1623
Query: 1043 AEIERKLEASNLTHNDELHKEKDDKESIMND-LDHVKAERQVLESKVSDMETTYSTLNNE 867
A +ER+L+ E+DD + +ND L+ E+ LES+ S+ TL +
Sbjct: 1624 AAMERQLQ------------ERDDALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQ 1671
Query: 866 LQQKMDDNEAFLNER-------------------DGLEAVKQGLEKRVLDLEATIHDIEM 744
LQ++ DD A LN+R D L A+++ L++R D A + D
Sbjct: 1672 LQER-DDALAALNDRLEEYGREKSALESRTSGSVDALAAMERQLQERD-DALAALKDRLE 1729
Query: 743 KTGKDDDYNEAEKQ-------TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE 585
+ G++ E+ TL++++ E ++A++ L D+ ++ ++ + S +E +
Sbjct: 1730 EYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSESVD 1789
Query: 584 DLNKESKEKQDLEKRVLELTSKL-----EKCICGARDGLSTIKEAWMSDCMV--PDNWVP 426
L ++ Q+ + + L +L EK + +R S A M + D
Sbjct: 1790 ALAAMERQLQERDDALAALKDRLEEHSREKSVLESRTSESVDALAAMERQLQERDDALAA 1849
Query: 425 FEDLVQGFSRKTSPLDITKTCDAVD 351
+D ++ SR+ S L+ ++T ++VD
Sbjct: 1850 LKDRLEEHSREKSALE-SRTSESVD 1873
Score = 123 bits (309), Expect = 7e-25
Identities = 174/703 (24%), Positives = 285/703 (40%), Gaps = 61/703 (8%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAG---KQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNIL 2271
E+DD +NDR LE K ALE++ ++ A+A ++ +
Sbjct: 708 ERDDALAALNDR--LEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEH 765
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR-NIVEADKQALENKVADFEAT 2094
K ALE++ + A+A + +L E+DD + DR +K ALE++ ++
Sbjct: 766 SREKSALESRTSESVDALAAMERQL-QERDDALAALKDRLEEYGREKSALESRTSESVDA 824
Query: 2093 IATLNDELLNEKDDKKCIVE-------ADKQALESKVSVFEAAIATLNDELLNEKDDKKC 1935
+ TL+ +L E+DD ++ +K ALES+ S A+A + +L E+DD
Sbjct: 825 VVTLSRQL-QERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQL-QERDDALA 882
Query: 1934 IVNDRNILEA---AKQALEYKVADLEAAKTTLNDELERKKD---------DNNAIIKKAL 1791
+ DR LE K ALE + ++ A TL +L+ + D + ++ K AL
Sbjct: 883 ALKDR--LEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREKSAL 940
Query: 1790 DKRISD----LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQ 1623
+ R S+ L A Q + DD A + + ++ V+ ++
Sbjct: 941 ESRTSESVDALAAMERQPQERDDALAALKDRLEEYSREKSALESRTSESVDAVVTLRRQL 1000
Query: 1622 KEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIM 1443
+E+DD A +KD LE SR E LE S
Sbjct: 1001 QERDDALAALKD----------------RLEEYSR----------EKSALESRTSESVDA 1034
Query: 1442 KAIREEELRKEKDGKSALVENGEGCEAEKQGLEK---------TVLERRASNLDTMDAIH 1290
A E +L++ D +AL + E EK LE +ERR D A
Sbjct: 1035 LAAMERQLQERDDALAALNDRLEEYSREKSALESRTSESVDALAAMERRLQERDDALAAL 1094
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL 1110
++ L + +KSAL E+ + + + + +LND L+ EK AL
Sbjct: 1095 KDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALNDR----LEEYGREKSAL 1150
Query: 1109 EKRCSD-----------LEAKN---ASLTDNQEGHEAEIERKLEASNLTHNDELH----- 987
E R S+ L+ ++ A+L D E H E + LE+ D L
Sbjct: 1151 ESRTSESVDAVVTLRRQLQERDDALAALKDRLEEHSRE-KSALESRTSESVDALAAMERQ 1209
Query: 986 -KEKDDKESIMND-LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER-DG 816
+E+DD + +ND L+ E+ LES+ S+ + + + Q++ DD A LN+R +
Sbjct: 1210 LQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQPQER-DDALAALNDRLEE 1268
Query: 815 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISE---LEEAISILTDK 645
K LE R + + + + + DD A K L++ E LE S D
Sbjct: 1269 YSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDA 1328
Query: 644 AKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
L + + + L++ L + S+EK LE R E L
Sbjct: 1329 VVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVGAL 1371
Score = 123 bits (308), Expect = 9e-25
Identities = 174/696 (25%), Positives = 287/696 (41%), Gaps = 38/696 (5%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAG---KQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNIL 2271
E+DD +NDR LE K ALE++ ++ A+A ++ +
Sbjct: 1506 ERDDALAALNDR--LEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEY 1563
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR-NIVEADKQALENKVADFEAT 2094
K ALE++ + A+ TL +L E+DD + DR +K ALE++ ++
Sbjct: 1564 SREKSALESRTSESVDAVVTLRRQL-QERDDALAALKDRLEEYSREKSALESRTSESVGA 1622
Query: 2093 IATLNDELLNEKDDKKCIV-------EADKQALESKVSVFEAAIATLNDELLNEKDDKKC 1935
+A + +L E+DD + + +K ALES+ S A+ TL +L E+DD
Sbjct: 1623 LAAMERQL-QERDDALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQL-QERDDALA 1680
Query: 1934 IVNDRNILEA---AKQALEYKVADLEAAKTTLNDELERKKDDNNAII---------KKAL 1791
+NDR LE K ALE + + A + +L+ + D A+ K AL
Sbjct: 1681 ALNDR--LEEYGREKSALESRTSGSVDALAAMERQLQERDDALAALKDRLEEYGREKSAL 1738
Query: 1790 DKRISDLKADAP-----QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1626
+ R S+ DA Q + DD A + + ++ V+ L E
Sbjct: 1739 ESRTSE-SVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSESVDALAAMERQ 1797
Query: 1625 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 1446
+E+DD A +KD L+EH E VLE S
Sbjct: 1798 LQERDDALAALKD-----------------------RLEEH---SREKSVLESRTSESVD 1831
Query: 1445 MKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI--HEEELRK 1272
A E +L++ D +AL + E+ EK+ LE R S +++DA+ +L++
Sbjct: 1832 ALAAMERQLQERDDALAALKD-----RLEEHSREKSALESRTS--ESVDAVVTLRRQLQE 1884
Query: 1271 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1092
+AL + E EK E + + +L LQ D + A K LE+ +
Sbjct: 1885 RDDALAALKDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSRE 1944
Query: 1091 LEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMND-LDHVKAERQVLE 915
A + +++ + A +ER+L+ E+DD + + D L+ E+ LE
Sbjct: 1945 KSALESRTSESVDA-LAAMERQLQ------------ERDDALAALKDKLEEYGREKSALE 1991
Query: 914 SKVSDMETTYSTLNNELQQKMDDNEAFLNER-DGLEAVKQGLEKRVLDLEATIHDIEMKT 738
S+ S+ TL +LQ++ DD A LN+R + K LE R + + +E +
Sbjct: 1992 SRTSESVDAVVTLRRQLQER-DDALAALNDRLEEHSREKSALESRTSESVDALAAMERQL 2050
Query: 737 GKDDDYNEAEKQTLK---KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKES 567
+ DD A L+ + S LE S D L + + + L + L + S
Sbjct: 2051 QERDDALAALNDKLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHS 2110
Query: 566 KEKQDLEKRVLELTSKL---EKCICGARDGLSTIKE 468
+EK LE R E L E+ + D L+ +K+
Sbjct: 2111 REKSALESRTSESVDALAAMERQLQERDDALAALKD 2146
Score = 89.0 bits (219), Expect = 2e-14
Identities = 137/598 (22%), Positives = 232/598 (38%), Gaps = 6/598 (1%)
Frame = -2
Query: 2126 LENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKD 1947
LE ++ + + +A LND+L +K LES+ S + TL + L E+D
Sbjct: 562 LERQLQERDDALAALNDKLEE--------YGREKSVLESRTSESVDVVVTL-ERQLQERD 612
Query: 1946 DKKCIVNDR-NILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL 1770
D + DR K LE + ++ TL +L+ D L
Sbjct: 613 DALAALKDRLEEHSREKSVLESRTSESVDVVVTLERQLQESVD---------------AL 657
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1590
A Q + DD A + + ++ V+ ++ +E+DD A +
Sbjct: 658 AAMERQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALN 717
Query: 1589 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1410
D L+EH E LE S A E +L++
Sbjct: 718 D-----------------------RLEEH---SREKSALESRTSESVDALAAMERQLQER 751
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
D +AL + E+ EK+ LE R S A E +L++ +AL + E
Sbjct: 752 DDALAALKD-----RLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEE 806
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
EK E + + +L+ LQ D + A K LE+ + A + +++ +
Sbjct: 807 YGREKSALESRTSESVDAVVTLSRQLQERDDALAALKDRLEEHSREKSALESRTSESVDA 866
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMND-LDHVKAERQVLESKVSDMETTYSTLN 873
A +ER+L+ E+DD + + D L+ E+ LES+ S+ TL
Sbjct: 867 -LAAMERQLQ------------ERDDALAALKDRLEEYGREKSALESRTSESVDAVVTLR 913
Query: 872 NELQQKMDDNEAFLNER-DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL 696
+LQ++ DD A LN+R + K LE R + + +E + + DD A K L
Sbjct: 914 RQLQER-DDALAALNDRLEEHSREKSALESRTSESVDALAAMERQPQERDDALAALKDRL 972
Query: 695 K---KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 525
+ + S LE S D L + + + L++ L + S+EK LE R E
Sbjct: 973 EEYSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSE-- 1030
Query: 524 SKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVD 351
+ D L+ ++ D D ++ +SR+ S L+ ++T ++VD
Sbjct: 1031 ---------SVDALAAMERQLQER---DDALAALNDRLEEYSREKSALE-SRTSESVD 1075
>ref|XP_001305955.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121887503|gb|EAX93025.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 2366
Score = 124 bits (311), Expect = 4e-25
Identities = 164/720 (22%), Positives = 313/720 (43%), Gaps = 93/720 (12%)
Frame = -2
Query: 2399 LEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQ---ALENKVGDF 2229
LEA K+A EN+ D + + T + N L+ AK+ ALE++V D
Sbjct: 930 LEAAKEASENENNDLKNDLQTKNKALSKAERDNDKLQNANKALDEAKEKIKALEDEVSDL 989
Query: 2228 EAAIATLNDELLNEKDDKKCIVNDRNIV--------------EADKQALENKVADFEATI 2091
+A ++ + +L EK + + +V +++ + +K L+ +V + E +
Sbjct: 990 KALVSEKDGDLQKEKRENERLVANKDQLTKNNEELYDQLKNETTEKIKLDGQVKNAERDL 1049
Query: 2090 A---------TLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIAT---LNDELLNEKD 1947
A T ++E L E++D+K +A + L++K++ E ++ L DE+ +K+
Sbjct: 1050 AKANATNEELTKSNEHLQEQNDEK---DAKIKELQAKLNELEKKLSELPGLQDEIAKQKE 1106
Query: 1946 DKKCIVNDRNILEAAKQ-------ALEYKVADLEAAKTTLND---ELE--RKKDDNNAII 1803
+ N+ N LE A + L+ K +LE K L D ELE +K DN+
Sbjct: 1107 TNNELQNNVNDLEKAGKDKDNKINELQKKANELENTKKDLEDVTNELENTQKDLDNSNNK 1166
Query: 1802 KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILIL---H 1635
+ L+K+I DLK ++E +D+ + +++ NL I L +
Sbjct: 1167 NRDLEKQIKDLKKQIEDLNREKNDLKDQLDTSKLAGDELSKRDEVLDNLRKQIAELAAKN 1226
Query: 1634 EELQKEKDDKTALIKDLVAAEPGKRTVN--------EIVSHLESKSRSLKEHFLREEEDE 1479
++L+ + +D A ++L A E +N E+ E + E+ +E+E++
Sbjct: 1227 KDLENKANDNNA--EELAAKEAELENINKQLEQTKKELAERDEELKNAKNENLAKEKENQ 1284
Query: 1478 VLERSASNLAI----MKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN- 1314
L R L +K + EEE + D +AL E + Q ++ + +N
Sbjct: 1285 KLNRENERLKFEQQDLKDL-EEENKNLDDENAALKSKVNALENDLQKAKRDADRLKLNND 1343
Query: 1313 -LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQ---R 1146
L T + +L++E +K L + + E Q + + + ND LQ +
Sbjct: 1344 QLQTNIDDLDNKLKEESAEKIKLDAQAKAADRELQSAKAATEEEK----KANDQLQGQIK 1399
Query: 1145 DLDRVMAEKQA----LEKRCSDL------------EAKNASLTDNQEGHEA-EIERKLEA 1017
D D + E QA ++K+ +D + +A+ ++N++ ++ E+++KL
Sbjct: 1400 DKDNKLKEMQAKLNEMQKKANDADRIQNLANSLKSQLDDANKSNNEKDNQLNELQKKLNE 1459
Query: 1016 SNLTHNDELHKEKDDKESIMNDLDHVKAE-------RQVLESKVSDMETTYSTLNNELQQ 858
+ N +L K + E NDL+ + E + LE ++ D++ LNNE Q
Sbjct: 1460 AQKKAN-QLEPTKQELEDARNDLNEKQKELDASNNKNRDLEKQIKDLKKQIGDLNNEKQA 1518
Query: 857 KMDDNEAFLNERDGL---EAVKQGLEKRVLDLEATIHDIEMKTGKDDD----YNEAEKQT 699
DD + D L + V L+K++ D A ++E K D+ +AE
Sbjct: 1519 LKDDLDTSKLADDELSKRDEVLGNLKKQLADQLAKNKELEAKVKGDNGDELAAKDAELDA 1578
Query: 698 LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 519
LK ++ ++++ ++ D+ K + + E+ +L DL + DLEK E+ ++
Sbjct: 1579 LKDQLEQVKKDLAETEDELKNARNESSAKDKEIQKLARDLEHLKDAEDDLEKANEEIKNR 1638
Score = 108 bits (271), Expect = 2e-20
Identities = 149/628 (23%), Positives = 281/628 (44%), Gaps = 42/628 (6%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATI 2091
EA +AL+N++ + + ++L N +++ + D + + + L N ++ +
Sbjct: 582 EAENRALQNQIDQLKKLLQGSEEDLKNAQNELQAKDKDLAKAQRENERLANAQNQLQSNL 641
Query: 2090 A---TLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND- 1923
L+DEL + K K +E +KQ E + +A +ND+L DD + D
Sbjct: 642 EEKKNLDDELTDLKS-KLAAIENEKQKAERENERLKA----MNDQLEKTSDDLNKKLTDE 696
Query: 1922 ---RNILEAAKQALEYKVADLEAAKTTL---NDELER-KKDDNNAIIKKALDKRISDLKA 1764
R L++ +A + ++ +AA L N++L+ KD +N I K L +++DL+
Sbjct: 697 TRERIKLDSQAKAADRELQTAKAASEELSKTNEQLDNFNKDKDNKI--KELQSKVNDLEK 754
Query: 1763 DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+ +Q DD N+ I +SN ++ +LQK+ D + D
Sbjct: 755 KS---NQLDDANSRIKELEDELSESEASKDDISNKLNDLQKKSNDLQKKSDQMKKDLDDS 811
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE--DEVLERSASNLAIMKAIREEELRKE 1410
K+ NE L+++ R L + E+ E+L ++ + I +++
Sbjct: 812 QQENAKKQKENE---DLQNQQRDLDKKLKAAEKRIQELLGENSDLHETLDNINTSSMQQG 868
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNL------DTMDAIHEEELRKEKVDKSAL 1248
+ + E +A ++ + + + N D M I + + ++DK
Sbjct: 869 DEMNKVIAEQAAKIKALQEAVNNSQPKGEDPNELHDKINDLMAQIKALQQKNNELDK--- 925
Query: 1247 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL---QRD----------LDRVMAEKQALE 1107
EN E EA K+ E DL+ + + N AL +RD LD + +ALE
Sbjct: 926 -ENKE-LEAAKEASENENNDLKNDLQTKNKALSKAERDNDKLQNANKALDEAKEKIKALE 983
Query: 1106 KRCSDLEAKNASLTDNQEGHEAEIERKL-EASNLT-HNDELHKE--KDDKESIMNDLDHV 939
SDL+A + + + + E ER + LT +N+EL+ + + E I D
Sbjct: 984 DEVSDLKALVSEKDGDLQKEKRENERLVANKDQLTKNNEELYDQLKNETTEKIKLDGQVK 1043
Query: 938 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 759
AER + ++ ++ E T S N LQ++ D+ +A + E L+A LEK++ +L
Sbjct: 1044 NAERDLAKANATNEELTKS--NEHLQEQNDEKDAKIKE---LQAKLNELEKKLSELPGLQ 1098
Query: 758 HDI----EMKTGKDDDYNEAEKQTLKK--RISELEEAISILTDKAKKLLKDINIWLSEVT 597
+I E ++ N+ EK K +I+EL++ + L + KK L+D+ +E+
Sbjct: 1099 DEIAKQKETNNELQNNVNDLEKAGKDKDNKINELQKKANEL-ENTKKDLEDVT---NELE 1154
Query: 596 ELQEDLNKESKEKQDLEKRVLELTSKLE 513
Q+DL+ + + +DLEK++ +L ++E
Sbjct: 1155 NTQKDLDNSNNKNRDLEKQIKDLKKQIE 1182
Score = 105 bits (263), Expect = 1e-19
Identities = 144/643 (22%), Positives = 277/643 (43%), Gaps = 56/643 (8%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKD---DKKCIVNDRNIVEADKQA--- 2127
N +N LE ++ LE+K + + A LND KD + + + + + + DK+
Sbjct: 488 NAKNELENLRKQLESKQNELKDAEKKLNDAKRKNKDLETENEALQDQVDSINTDKEQQGD 547
Query: 2126 ----LENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELL 1959
L ++D A N++ E + + EA+ +AL++++ + + ++L
Sbjct: 548 ELANLRKMLSDQTANFKKNNEDNKKENEKELAKKEAENRALQNQIDQLKKLLQGSEEDLK 607
Query: 1958 NEKDDKKCIVNDRNILEAAKQ------ALEYKVADLEAAKTTLNDELERKKDDNNAII-- 1803
N +++ + D+++ +A ++ A ++LE K L+DEL K AI
Sbjct: 608 NAQNELQA--KDKDLAKAQRENERLANAQNQLQSNLEEKKN-LDDELTDLKSKLAAIENE 664
Query: 1802 KKALDKRISDLKADAPQRDQ-EDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1626
K+ ++ LKA Q ++ DD+N + K EEL
Sbjct: 665 KQKAERENERLKAMNDQLEKTSDDLNKKLTDETRERIKLDSQAKAADRELQTAKAASEEL 724
Query: 1625 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNL 1452
K + KD + + + V+ LE KS L + ++E EDE+ E AS
Sbjct: 725 SKTNEQLDNFNKD---KDNKIKELQSKVNDLEKKSNQLDDANSRIKELEDELSESEASKD 781
Query: 1451 AIMKAIRE-----EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 1287
I + + +L+K+ D +++ + A+KQ E L+ + +LD E
Sbjct: 782 DISNKLNDLQKKSNDLQKKSDQMKKDLDDSQQENAKKQK-ENEDLQNQQRDLDKKLKAAE 840
Query: 1286 EELRKEKVDKSALTENGEGCEAE--KQGPE--KTVLDLEPTIPSLNDALQRD-------- 1143
+ +++ + S L E + +QG E K + + I +L +A+
Sbjct: 841 KRIQELLGENSDLHETLDNINTSSMQQGDEMNKVIAEQAAKIKALQEAVNNSQPKGEDPN 900
Query: 1142 -----LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEK 978
++ +MA+ +AL+++ ++L+ +N L +E E E L+ T N L K +
Sbjct: 901 ELHDKINDLMAQIKALQQKNNELDKENKELEAAKEASENE-NNDLKNDLQTKNKALSKAE 959
Query: 977 DDKESIMND---LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 807
D + + N LD K + + LE +VSD++ S + +LQ++ +NE + +D L
Sbjct: 960 RDNDKLQNANKALDEAKEKIKALEDEVSDLKALVSEKDGDLQKEKRENERLVANKDQLTK 1019
Query: 806 VKQGLEKRV-------LDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 648
+ L ++ + L+ + + E K + NE L K L+E
Sbjct: 1020 NNEELYDQLKNETTEKIKLDGQVKNAERDLAKANATNE----ELTKSNEHLQEQNDEKDA 1075
Query: 647 KAKKL---LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 528
K K+L L ++ LSE+ LQ+++ K+ + +L+ V +L
Sbjct: 1076 KIKELQAKLNELEKKLSELPGLQDEIAKQKETNNELQNNVNDL 1118
Score = 96.3 bits (238), Expect = 1e-16
Identities = 135/634 (21%), Positives = 265/634 (41%), Gaps = 48/634 (7%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQ---ALENKVADF 2103
LEAAK+A EN+ D + + T N L + D + N ++ K+ ALE++V+D
Sbjct: 930 LEAAKEASENENNDLKNDLQTKNKALSKAERDNDKLQNANKALDEAKEKIKALEDEVSDL 989
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+A ++ + +L EK + + +V Q ++ ++ D+L NE +K I D
Sbjct: 990 KALVSEKDGDLQKEKRENERLVANKDQLTKNNEELY--------DQLKNETTEK--IKLD 1039
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA------LDKRISDLKAD 1761
+ A + + + E K+ N+ L+ + D+ +A IK+ L+K++S+L
Sbjct: 1040 GQVKNAERDLAKANATNEELTKS--NEHLQEQNDEKDAKIKELQAKLNELEKKLSELPGL 1097
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK-TALIKDL 1584
+ ++ + N + L+ N+ L E+ K+KD+K L K
Sbjct: 1098 QDEIAKQKETN--------------------NELQNNVNDL-EKAGKDKDNKINELQKKA 1136
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
E K+ + ++ + LE+ + L ++ LE+ +L K I E+L +EK+
Sbjct: 1137 NELENTKKDLEDVTNELENTQKDLDNS---NNKNRDLEKQIKDLK--KQI--EDLNREKN 1189
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTM-DAIHEEELRKEKVDKSALTENGEGC 1227
++ + L L +R LD + I E + + ++ A N E
Sbjct: 1190 DLKDQLDTSK--------LAGDELSKRDEVLDNLRKQIAELAAKNKDLENKANDNNAEEL 1241
Query: 1226 EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGH 1047
A++ E LE T L + +L E A EK L +N L Q+
Sbjct: 1242 AAKEAELENINKQLEQTKKELAER-DEELKNAKNENLAKEKENQKLNRENERLKFEQQDL 1300
Query: 1046 EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN- 870
+ LE N +DE K ++ NDL K + L+ ++T L+N
Sbjct: 1301 -----KDLEEENKNLDDENAALKSKVNALENDLQKAKRDADRLKLNNDQLQTNIDDLDNK 1355
Query: 869 --------------------ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 750
ELQ E D L+ + + ++ +++A ++++
Sbjct: 1356 LKEESAEKIKLDAQAKAADRELQSAKAATEEEKKANDQLQGQIKDKDNKLKEMQAKLNEM 1415
Query: 749 EMKTGKDD-----------DYNEAEKQTLKK--RISELEEAISILTDKAKKL---LKDIN 618
+ K D ++A K +K +++EL++ ++ KA +L +++
Sbjct: 1416 QKKANDADRIQNLANSLKSQLDDANKSNNEKDNQLNELQKKLNEAQKKANQLEPTKQELE 1475
Query: 617 IWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
+++ E Q++L+ + + +DLEK++ +L ++
Sbjct: 1476 DARNDLNEKQKELDASNNKNRDLEKQIKDLKKQI 1509
Score = 95.9 bits (237), Expect = 2e-16
Identities = 146/660 (22%), Positives = 270/660 (40%), Gaps = 84/660 (12%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAA---IATLNDELLNEKDD--KKCIVNDRNIVEADKQALENKVA 2109
L++ A+EN+ E + +ND+L DD KK R ++ D QA K A
Sbjct: 654 LKSKLAAIENEKQKAERENERLKAMNDQLEKTSDDLNKKLTDETRERIKLDSQA---KAA 710
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADK----QALESKVSVFEAAIATLNDELLNEKDDK 1941
D E A E L++ +++ DK + L+SKV+ E L+D K+
Sbjct: 711 DRELQTAKAASEELSKTNEQLDNFNKDKDNKIKELQSKVNDLEKKSNQLDDANSRIKE-- 768
Query: 1940 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
+ ++ + EA+K + K+ DL+ L + ++ K D + ++ K+ +
Sbjct: 769 --LEDELSESEASKDDISNKLNDLQKKSNDLQKKSDQMKKDLDDSQQENAKKQKENEDLQ 826
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1581
QRD + + A + + N+ + + +E+ K ++ A IK L
Sbjct: 827 NQQRDLDKKLKAAEKRIQELLGENSDLHETLDNINTSSMQQGDEMNKVIAEQAAKIKALQ 886
Query: 1580 AAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSASNLAIMKAIREEE---LRK 1413
A + E + L K L ++++ L++ L K E E L+
Sbjct: 887 EAVNNSQPKGEDPNELHDKINDLMAQIKALQQKNNELDKENKELEAAKEASENENNDLKN 946
Query: 1412 EKDGKSALVENGEGCEAEKQGLEKTV---------LERRASNLDTMDAIHEEELRKEK-- 1266
+ K+ + E + Q K + LE S+L + + + +L+KEK
Sbjct: 947 DLQTKNKALSKAERDNDKLQNANKALDEAKEKIKALEDEVSDLKALVSEKDGDLQKEKRE 1006
Query: 1265 -----VDKSALTENGEGC--EAEKQGPEKTVLD---------------LEPTIPSLNDAL 1152
+K LT+N E + + + EK LD + N+ L
Sbjct: 1007 NERLVANKDQLTKNNEELYDQLKNETTEKIKLDGQVKNAERDLAKANATNEELTKSNEHL 1066
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-------- 996
Q D A+ + L+ + ++LE K + L Q+ EI ++ E +N N+
Sbjct: 1067 QEQNDEKDAKIKELQAKLNELEKKLSELPGLQD----EIAKQKETNNELQNNVNDLEKAG 1122
Query: 995 ---------------ELHKEKDDKESIMN-------DLDHVKAERQVLESKVSDMETTYS 882
EL K D E + N DLD+ + + LE ++ D++
Sbjct: 1123 KDKDNKINELQKKANELENTKKDLEDVTNELENTQKDLDNSNNKNRDLEKQIKDLKKQIE 1182
Query: 881 TLN---NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA 711
LN N+L+ ++D ++ +E + V L K++ +L A D+E K ++ A
Sbjct: 1183 DLNREKNDLKDQLDTSKLAGDELSKRDEVLDNLRKQIAELAAKNKDLENKANDNNAEELA 1242
Query: 710 EKQTLKKRIS-ELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK----EKQDLE 546
K+ + I+ +LE+ L ++ ++L N L++ E Q+ LN+E++ E+QDL+
Sbjct: 1243 AKEAELENINKQLEQTKKELAERDEELKNAKNENLAKEKENQK-LNRENERLKFEQQDLK 1301
Score = 94.0 bits (232), Expect = 6e-16
Identities = 142/658 (21%), Positives = 270/658 (41%), Gaps = 26/658 (3%)
Frame = -2
Query: 2441 EKDDKKYVV--NDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILE 2268
E DKKY + N +N E G ++ K+A E A + V L+
Sbjct: 346 EDSDKKYKLLENQQNQSEEGARS---KLAGMEVEFARLQKENNDLKPKLQDEVAKNKELQ 402
Query: 2267 AAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQA----LENKVADFE 2100
+ L++++ + + ++A ++ +++ + + N VEA +Q ++ + D +
Sbjct: 403 NQIENLQDQIDELKRSLAEAQKQIKDKEAEIADVKNQLQGVEASQQQQNANAQDTLKDKD 462
Query: 2099 ATIATLND----------ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEK 1950
A I LN+ +L N+ D+ K +E ++ LESK + + A LND K
Sbjct: 463 AKINDLNNKLKDNNKAINDLQNQLDNAKNELENLRKQLESKQNELKDAEKKLNDAKRKNK 522
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL 1770
D LE +AL+ +V + K DEL A ++K L + ++
Sbjct: 523 D-----------LETENEALQDQVDSINTDKEQQGDEL--------ANLRKMLSDQTANF 563
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1590
K ++ ED+ + L+ + E+L+ +++ A K
Sbjct: 564 K-----KNNEDNKKENEKELAKKEAENRALQNQIDQLKKLLQGSEEDLKNAQNELQAKDK 618
Query: 1589 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1410
DL A+ NE +++ +++ +S E ++ D+ L S LA AI E+ + E
Sbjct: 619 DLAKAQ----RENERLANAQNQLQSNLEE--KKNLDDELTDLKSKLA---AIENEKQKAE 669
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
++ + N + LE+ + +L+ ++L E ++ L +
Sbjct: 670 RENERLKAMNDQ-------------LEKTSDDLN-------KKLTDETRERIKLDSQAKA 709
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+ E Q + +L T L D +D D + E L+ + +DLE K+ L D+
Sbjct: 710 ADRELQTAKAASEELSKTNEQL-DNFNKDKDNKIKE---LQSKVNDLEKKSNQL-DDANS 764
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 870
E+E DEL + + K+ I N L+ ++ + L+ K M+
Sbjct: 765 RIKELE-----------DELSESEASKDDISNKLNDLQKKSNDLQKKSDQMKKDLDDSQQ 813
Query: 869 ELQQKMDDNEAFLNERDGLEAVKQGLEKRV-------LDLEATIHDIEMKTGKDDDYNEA 711
E +K +NE N++ L+ + EKR+ DL T+ +I + + D
Sbjct: 814 ENAKKQKENEDLQNQQRDLDKKLKAAEKRIQELLGENSDLHETLDNINTSSMQQGDEMNK 873
Query: 710 EKQTLKKRISELEEAISILTDKAK---KLLKDINIWLSEVTELQEDLNKESKEKQDLE 546
+I L+EA++ K + +L IN ++++ LQ+ N+ KE ++LE
Sbjct: 874 VIAEQAAKIKALQEAVNNSQPKGEDPNELHDKINDLMAQIKALQQKNNELDKENKELE 931
Score = 92.4 bits (228), Expect = 2e-15
Identities = 148/666 (22%), Positives = 291/666 (43%), Gaps = 76/666 (11%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDEL--LNEKDDKKCIVNDRNIVEADKQALENKVADFE 2100
++A + L+N+ DFE L D+L L ++ DK+ + + + + + LE K D E
Sbjct: 218 IDALNKELQNQQQDFEKQKNDLQDQLKRLQDQLDKQTAESQQLKSQIENKDLEGKDKDSE 277
Query: 2099 ATIATLNDELLNEKDDKKC---------IVEADKQ------ALESKVSVFEAAIATL--- 1974
I L +LL +KD+K I + +KQ AL+ AA+ L
Sbjct: 278 --IEKLK-KLLKDKDNKSKNDLDEANANIDDLNKQLDQLRNALKDANKQKAAALDDLEKE 334
Query: 1973 ---NDELLNEKDDK----KCIVNDRNILEAAKQA----LEYKVADLEAA----KTTLNDE 1839
N +L N+ +D K + N +N E ++ +E + A L+ K L DE
Sbjct: 335 RDANSDLKNKLEDSDKKYKLLENQQNQSEEGARSKLAGMEVEFARLQKENNDLKPKLQDE 394
Query: 1838 LERKKDDNNAIIKKALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSN 1662
+ + K+ N I + L +I +LK A + Q D A I +
Sbjct: 395 VAKNKELQNQI--ENLQDQIDELKRSLAEAQKQIKDKEAEIADVKNQ----------LQG 442
Query: 1661 LEVNILILHEELQKEKDDKTALIKDLV-AAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 1485
+E + + Q DK A I DL + + +N++ + L++ L+ LR++
Sbjct: 443 VEASQQQQNANAQDTLKDKDAKINDLNNKLKDNNKAINDLQNQLDNAKNELEN--LRKQ- 499
Query: 1484 DEVLERSASNLAIMKAIREEELRKEKDGKS---ALVENGEGCEAEKQ-------GLEKTV 1335
LE + L + + RK KD ++ AL + + +K+ L K +
Sbjct: 500 ---LESKQNELKDAEKKLNDAKRKNKDLETENEALQDQVDSINTDKEQQGDELANLRKML 556
Query: 1334 LERRAS---NLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSL 1164
++ A+ N + +E+EL K++ + AL + + QG E+ + + + + +
Sbjct: 557 SDQTANFKKNNEDNKKENEKELAKKEAENRALQNQIDQLKKLLQGSEEDLKNAQNELQAK 616
Query: 1163 NDAL---QRDLDRV----------MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL 1023
+ L QR+ +R+ + EK+ L+ +DL++K A++ + ++ E E ER L
Sbjct: 617 DKDLAKAQRENERLANAQNQLQSNLEEKKNLDDELTDLKSKLAAIENEKQKAERENER-L 675
Query: 1022 EASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 843
+A N D+L K DD + D ER L+S+ + ELQ +
Sbjct: 676 KAMN----DQLEKTSDDLNKKLTDETR---ERIKLDSQAK-------AADRELQTAKAAS 721
Query: 842 EAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYN-------------EAEKQ 702
E + L+ + + ++ +L++ ++D+E K+ + DD N EA K
Sbjct: 722 EELSKTNEQLDNFNKDKDNKIKELQSKVNDLEKKSNQLDDANSRIKELEDELSESEASKD 781
Query: 701 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 522
+ ++++L++ + L K+ ++ KD++ E + Q++ +++DL+K++
Sbjct: 782 DISNKLNDLQKKSNDLQKKSDQMKKDLDDSQQENAKKQKENEDLQNQQRDLDKKLKAAEK 841
Query: 521 KLEKCI 504
++++ +
Sbjct: 842 RIQELL 847
Score = 89.4 bits (220), Expect = 1e-14
Identities = 147/669 (21%), Positives = 279/669 (41%), Gaps = 74/669 (11%)
Frame = -2
Query: 2252 LENKVGDFEAAIA-TLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLND 2076
L NK+ + E + TLND LN K D N+ + +QA K+AD + +L
Sbjct: 133 LNNKLDEAEKKLKDTLND--LNPKIDSLTAENENLKKQLQEQA--PKLADMDNLTKSLK- 187
Query: 2075 ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND-RNILEAAK 1899
+L ++ K +E K+ + + + I LN EL N++ D + ND ++ L+ +
Sbjct: 188 KLTRMQEKAKQELENQKKQNADQENKYNQDIDALNKELQNQQQDFEKQKNDLQDQLKRLQ 247
Query: 1898 QALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALI 1719
L+ + A+ + K+ + ++ KD ++ I K L K + D D ++ D+ NA I
Sbjct: 248 DQLDKQTAESQQLKSQIENKDLEGKDKDSEIEK--LKKLLKD--KDNKSKNDLDEANANI 303
Query: 1718 XXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 1539
+L + L L+ K A + DL E + +++ +
Sbjct: 304 -----------------DDLNKQLDQLRNALKDANKQKAAALDDL---EKERDANSDLKN 343
Query: 1538 HLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAE 1359
LE + K L ++++ E + S LA M+ + L+KE + +++ E
Sbjct: 344 KLEDSDKKYK--LLENQQNQSEEGARSKLAGME-VEFARLQKENNDLKPKLQDEVAKNKE 400
Query: 1358 KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ----GPEKTVL 1191
Q + L+ + L A +++++ ++ + + + +G EA +Q + T+
Sbjct: 401 LQNQIEN-LQDQIDELKRSLAEAQKQIKDKEAEIADVKNQLQGVEASQQQQNANAQDTLK 459
Query: 1190 DLEPTIPSLNDAL----------QRDLDRVMAEKQALEKRCS------------------ 1095
D + I LN+ L Q LD E + L K+
Sbjct: 460 DKDAKINDLNNKLKDNNKAINDLQNQLDNAKNELENLRKQLESKQNELKDAEKKLNDAKR 519
Query: 1094 ---DLEAKNASLTDN---------QEGHEAEIERKL---EASNLTHNDELHKEKDDKE-- 966
DLE +N +L D Q+G E RK+ + +N N+E +K++++KE
Sbjct: 520 KNKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNNEDNKKENEKELA 579
Query: 965 -------SIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 807
++ N +D +K Q E + + + + +L + +NE N ++ L++
Sbjct: 580 KKEAENRALQNQIDQLKKLLQGSEEDLKNAQNELQAKDKDLAKAQRENERLANAQNQLQS 639
Query: 806 ---VKQGLEKRVLDLEATIHDIEMKTGKDDDYNE---AEKQTLKKRISELEEAISILTDK 645
K+ L+ + DL++ + IE + K + NE A L+K +L + ++ T +
Sbjct: 640 NLEEKKNLDDELTDLKSKLAAIENEKQKAERENERLKAMNDQLEKTSDDLNKKLTDETRE 699
Query: 644 AKKL----------LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGA 495
KL L+ E+++ E L+ +K+K + K + + LEK
Sbjct: 700 RIKLDSQAKAADRELQTAKAASEELSKTNEQLDNFNKDKDNKIKELQSKVNDLEKKSNQL 759
Query: 494 RDGLSTIKE 468
D S IKE
Sbjct: 760 DDANSRIKE 768
Score = 88.2 bits (217), Expect = 3e-14
Identities = 138/611 (22%), Positives = 259/611 (42%), Gaps = 35/611 (5%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAA-------IATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
L+A + LE ++G AA I L E ++ + K + + N ++ +N
Sbjct: 1694 LDAQVKELERRLGTNNAAQEQQAQTIEQLKSEAADKDNKIKDLHDQINNLQKKANDADNL 1753
Query: 2114 VADFEATIATLNDELLNEKDDKKCIVEADKQALES--KVSVFEAAIATLNDEL--LNEKD 1947
+ + L++ + D + E K+ ES K + E L D LNEK
Sbjct: 1754 QQQLDYAKSQLDEANKSNNDKDNQLNELQKKFNESQKKANQLEPTKQELEDSRNDLNEKQ 1813
Query: 1946 DKKCIVNDRNI-LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL 1770
+ N++N LE + L+ ++ DL+ K L ++L+ ++ I K L K+I++L
Sbjct: 1814 KELDESNNKNRDLEKQIKELKKQIEDLKKQKDDLQEQLDNNVKADDVIDK--LRKQIAEL 1871
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH-EELQKEKDDKTALI 1593
A + + ++ N V + E+ L E+ +K+ D+K +
Sbjct: 1872 LAKVKELEAKNKDNT-------------GDELAVKDAEIESLKNQFEQAKKDLDEKELEL 1918
Query: 1592 K----DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREE 1425
K +L + + + N + L+ + L + EE++ L+ L A E
Sbjct: 1919 KQTSDNLSSKDKELQKANRELERLQDVDQELAQ---ANEENKKLDAENGELKTQLANTEN 1975
Query: 1424 ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALT 1245
EL+K K L + + L K + + N+ I E + R D +A+
Sbjct: 1976 ELQKSKQDNERLQSSNDQLTKNTDDLNKKLTDETTDNIKLNGLIQELQRRLANND-AAIA 2034
Query: 1244 ENGEGCEA-EKQGPEKT--VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 1074
+ E + +Q +K + DL I +L D D + +Q L+ S L+ N
Sbjct: 2035 QQAESIDKLNEQAADKDNKIKDLHDQINNLQKKAN-DADNL---QQQLDYAKSQLDEANK 2090
Query: 1073 SLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAE-------RQVLE 915
S D ++ E+++K S N +L K + E NDL+ + E + LE
Sbjct: 2091 SNND-KDNQLNELQKKFNESQKKAN-QLEPTKQELEDSRNDLNEKQKELDESNNKNRDLE 2148
Query: 914 SKVSDMETTYSTLNNE---LQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 744
++ +++ L++E LQ K+DD + + + V L K++ +L A D+E
Sbjct: 2149 KQIKELKKQIGNLDSEKQALQDKLDDIKLADDAISKRDEVLDNLRKQIAELAAKNKDLEN 2208
Query: 743 KTGKDDDYNEAEKQTLKKRIS-ELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKES 567
K ++ A K+ + I+ +LE+ L ++ ++L N L++ E Q+ LN+E+
Sbjct: 2209 KANDNNAEELAAKEAELENINKQLEQTKKELAERDEELKNAKNENLAKEKENQK-LNREN 2267
Query: 566 K----EKQDLE 546
+ E+QDL+
Sbjct: 2268 ERLKFEQQDLK 2278
Score = 87.0 bits (214), Expect = 7e-14
Identities = 128/664 (19%), Positives = 275/664 (41%), Gaps = 74/664 (11%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVE-ADKQA----- 2127
ND N + A NK D E I L ++ + ++K+ + +D + + AD +
Sbjct: 1479 NDLNEKQKELDASNNKNRDLEKQIKDLKKQIGDLNNEKQALKDDLDTSKLADDELSKRDE 1538
Query: 2126 ----LENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELL 1959
L+ ++AD A L ++ + D+ +A+ AL+ ++ + +A DEL
Sbjct: 1539 VLGNLKKQLADQLAKNKELEAKVKGDNGDELAAKDAELDALKDQLEQVKKDLAETEDELK 1598
Query: 1958 NEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRI 1779
N +++ D+ I + A+ K A+ + K N+E++ + +NN + K L +
Sbjct: 1599 NARNESSA--KDKEIQKLARDLEHLKDAEDDLEKA--NEEIKNRDAENNEL-KGQLANKE 1653
Query: 1778 SDLKADAPQRDQ-----------EDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
++L+ + D+ DD+N + N++++ + +
Sbjct: 1654 NELQKSKQENDRLQLSKDQLSKHNDDLNNQLTAAT------------TDNIKLDAQV--K 1699
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 1452
EL++ A A E +T+ ++ S K +K+ L ++ + + +++
Sbjct: 1700 ELERRLGTNNA------AQEQQAQTIEQLKSEAADKDNKIKD--LHDQINNLQKKANDAD 1751
Query: 1451 AIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD-TMDAIHEEELR 1275
+ + + + + ++ KS ++ + E +K+ E +++A+ L+ T + +
Sbjct: 1752 NLQQQLDYAKSQLDEANKSNNDKDNQLNELQKKFNES---QKKANQLEPTKQELEDSRND 1808
Query: 1274 KEKVDKSALTENGEGCEAEKQGPE--KTVLDLEPTIPSLNDALQRD------LDRVMAEK 1119
+ K N + + EKQ E K + DL+ L + L + +D++ +
Sbjct: 1809 LNEKQKELDESNNKNRDLEKQIKELKKQIEDLKKQKDDLQEQLDNNVKADDVIDKLRKQI 1868
Query: 1118 QALEKRCSDLEAKNASLTDNQ--------------------EGHEAEIERKLEASNLTHN 999
L + +LEAKN T ++ + E E+E K + NL+
Sbjct: 1869 AELLAKVKELEAKNKDNTGDELAVKDAEIESLKNQFEQAKKDLDEKELELKQTSDNLSSK 1928
Query: 998 D-ELHKEKDDKESIMN---DLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 831
D EL K + E + + +L E + L+++ +++T + NELQ+ DNE
Sbjct: 1929 DKELQKANRELERLQDVDQELAQANEENKKLDAENGELKTQLANTENELQKSKQDNERLQ 1988
Query: 830 NERDGLEAVKQGLEKRVLD-------LEATIHDIEMKTGKDDDYNEAEKQTLKK------ 690
+ D L L K++ D L I +++ + +D + +++ K
Sbjct: 1989 SSNDQLTKNTDDLNKKLTDETTDNIKLNGLIQELQRRLANNDAAIAQQAESIDKLNEQAA 2048
Query: 689 ----RISELEEAISILTDKAK---KLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 531
+I +L + I+ L KA L + ++ S++ E + N + + +L+K+ E
Sbjct: 2049 DKDNKIKDLHDQINNLQKKANDADNLQQQLDYAKSQLDEANKSNNDKDNQLNELQKKFNE 2108
Query: 530 LTSK 519
K
Sbjct: 2109 SQKK 2112
Score = 84.3 bits (207), Expect = 5e-13
Identities = 139/614 (22%), Positives = 264/614 (42%), Gaps = 49/614 (7%)
Frame = -2
Query: 2204 DELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL---NDELLNEKDDKKCIVE 2034
DE L E+ ++ D I K++ EN+ A +EAT+ +++L D++ +
Sbjct: 74 DEYLTERQNQ----TDNQI----KESKENQ-AKYEATLRQAVKKHNQLTKLLQDREQAIA 124
Query: 2033 ADKQALESKVSVFEAAIATLNDEL--LNEKDDKKCIVNDRNILEAAKQALEYKVADL--- 1869
+ +E+ + + A L D L LN K D N+ + +QA K+AD+
Sbjct: 125 RSGEEVENLNNKLDEAEKKLKDTLNDLNPKIDSLTAENENLKKQLQEQAP--KLADMDNL 182
Query: 1868 -----------EAAKTTLNDELERKKDDNNAIIKK--ALDKRISDLKADAPQR--DQEDD 1734
E AK L ++ ++ D N + AL+K + + + D ++ D +D
Sbjct: 183 TKSLKKLTRMQEKAKQELENQKKQNADQENKYNQDIDALNKELQNQQQDFEKQKNDLQDQ 242
Query: 1733 MNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQ-KEKDDKTALIKDLVAAEPGK-- 1563
+ L + + ++ I +++L+ K+KD + +K L+ + K
Sbjct: 243 LKRL---------QDQLDKQTAESQQLKSQIENKDLEGKDKDSEIEKLKKLLKDKDNKSK 293
Query: 1562 RTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVE 1383
++E ++++ ++ L + L + + KA ++L KE+D S L
Sbjct: 294 NDLDEANANIDDLNKQLDQ----------LRNALKDANKQKAAALDDLEKERDANSDLKN 343
Query: 1382 NGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE 1203
E + + + LE + + + E R +K EN + + + Q
Sbjct: 344 KLEDSDKKYKLLENQQNQSEEGARSKLAGMEVEFARLQK-------ENND-LKPKLQDEV 395
Query: 1202 KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK- 1026
+L+ I +L D + +L R +AE Q K+ D EA+ A + + +G EA +++
Sbjct: 396 AKNKELQNQIENLQDQID-ELKRSLAEAQ---KQIKDKEAEIADVKNQLQGVEASQQQQN 451
Query: 1025 ------LEASNLTHNDELHKEKDDKESI---MNDLDHVKAE----RQVLESKVSDMETTY 885
L+ + ND +K KD+ ++I N LD+ K E R+ LESK ++++
Sbjct: 452 ANAQDTLKDKDAKINDLNNKLKDNNKAINDLQNQLDNAKNELENLRKQLESKQNELKDAE 511
Query: 884 STLNNELQQKMD---DNEAFLNERDGLEAVKQGLEKRVLDLEATIHD--IEMKTGKDDDY 720
LN+ ++ D +NEA ++ D + K+ + +L + D K +D+
Sbjct: 512 KKLNDAKRKNKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNNEDNK 571
Query: 719 NEAEKQTLKKRISELEEAISILTDKAKKLL----KDINIWLSEVTELQEDLNKESKEKQD 552
E EK+ KK A+ D+ KKLL +D+ +E+ +DL K +E +
Sbjct: 572 KENEKELAKKEAEN--RALQNQIDQLKKLLQGSEEDLKNAQNELQAKDKDLAKAQRENER 629
Query: 551 LEKRVLELTSKLEK 510
L +L S LE+
Sbjct: 630 LANAQNQLQSNLEE 643
Score = 80.1 bits (196), Expect = 9e-12
Identities = 143/632 (22%), Positives = 270/632 (42%), Gaps = 48/632 (7%)
Frame = -2
Query: 2279 NILEAAKQ---ALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N L+ AK+ L+ + I L+++L E +K I D AD++ K A
Sbjct: 1326 NDLQKAKRDADRLKLNNDQLQTNIDDLDNKLKEESAEK--IKLDAQAKAADRELQSAKAA 1383
Query: 2108 DFEATIATLNDEL---LNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
E A ND+L + +KD+K ++A ++ K + + I L + L ++ DD
Sbjct: 1384 TEEEKKA--NDQLQGQIKDKDNKLKEMQAKLNEMQKKANDADR-IQNLANSLKSQLDDAN 1440
Query: 1937 CIVNDRN---------ILEAAKQA--LEYKVADLEAAKTTLNDELERKKDDNNAIIKKAL 1791
N+++ + EA K+A LE +LE A+ LN++ + NN + L
Sbjct: 1441 KSNNEKDNQLNELQKKLNEAQKKANQLEPTKQELEDARNDLNEKQKELDASNNK--NRDL 1498
Query: 1790 DKRISDLKADAPQRDQE-----DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE- 1629
+K+I DLK + E DD++ S L + L +E
Sbjct: 1499 EKQIKDLKKQIGDLNNEKQALKDDLDT-------------------SKLADDELSKRDEV 1539
Query: 1628 ---LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF------LREEEDEV 1476
L+K+ D+ A K+L A G + ++ +++ +LK+ L E EDE+
Sbjct: 1540 LGNLKKQLADQLAKNKELEAKVKGDN--GDELAAKDAELDALKDQLEQVKKDLAETEDEL 1597
Query: 1475 L----ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1308
E SA + I K R+ L KD + L + E E + + E L+ + +N +
Sbjct: 1598 KNARNESSAKDKEIQKLARD--LEHLKDAEDDLEKANE--EIKNRDAENNELKGQLANKE 1653
Query: 1307 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1128
++E + ++ K L+++ + + + L+ + L L +
Sbjct: 1654 NELQKSKQENDRLQLSKDQLSKHNDDLNNQLTAATTDNIKLDAQVKELERRLGTNNAAQE 1713
Query: 1127 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHN--------DELHKEKDD 972
+ Q +E+ S+ K+ + D + ++ +A NL DE +K +D
Sbjct: 1714 QQAQTIEQLKSEAADKDNKIKDLHDQINNLQKKANDADNLQQQLDYAKSQLDEANKSNND 1773
Query: 971 KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 792
K++ +N+L E Q +++ + N+L +K + + N+ LE + L
Sbjct: 1774 KDNQLNELQKKFNESQKKANQLEPTKQELEDSRNDLNEKQKELDESNNKNRDLEKQIKEL 1833
Query: 791 EKRVLDLEATIHDIEMKTG---KDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD- 624
+K++ DL+ D++ + K DD + L+K+I+EL + L K K D
Sbjct: 1834 KKQIEDLKKQKDDLQEQLDNNVKADDVID----KLRKQIAELLAKVKELEAKNKDNTGDE 1889
Query: 623 INIWLSEVTELQEDLNKESKEKQDLEKRVLEL 528
+ + +E+ L+ N+ + K+DL+++ LEL
Sbjct: 1890 LAVKDAEIESLK---NQFEQAKKDLDEKELEL 1918
>ref|XP_005159739.1| PREDICTED: uncharacterized protein si:ch211-250g4.3 isoform X2 [Danio
rerio]
Length = 15734
Score = 124 bits (310), Expect = 5e-25
Identities = 150/671 (22%), Positives = 288/671 (42%), Gaps = 69/671 (10%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ E KQ +E + D
Sbjct: 4636 EKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHD 4695
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
F+ + +L+++L K K+ I E + + K+ + A DE+ K++ + N
Sbjct: 4696 FDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREA-----DEIRKVKEETQ---N 4747
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
+R I E +AL+ + DL N L+ K N + + L +R S+L ++
Sbjct: 4748 ERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRER-SNL------QE 4800
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDL-- 1584
++++ + + L+ I E +KEK ++ A+IKD+
Sbjct: 4801 MRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVED 4860
Query: 1583 -------------------VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE------ 1479
A E K + ++ + LE ++ +++ L + D
Sbjct: 4861 LQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHDRQRVEEM 4920
Query: 1478 ----VLERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VL 1332
ER N I + R++ + E K+ A+ + + E EK LEKT L
Sbjct: 4921 TAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKL 4980
Query: 1331 ERRASNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTI 1173
R NL+ I E++KE+ D + E + + E+ ++ LD L+ I
Sbjct: 4981 LRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEI 5040
Query: 1172 PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHN 999
+L L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K +
Sbjct: 5041 QNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQK 5100
Query: 998 DELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 831
E+ KEK D ++S+ DL +K ++QVLE + S +E L E + E
Sbjct: 5101 QEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQ 5160
Query: 830 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEE 669
NER LE + + L++ DL + + D+ A + TL K + E+ E
Sbjct: 5161 NERQNLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRE 5217
Query: 668 AISILTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE---- 513
IS T+ + +++ + E+ +LQ +++K+ KEK ++E + +E
Sbjct: 5218 NISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQH 5277
Query: 512 KCICGARDGLS 480
K IC RD S
Sbjct: 5278 KIICLDRDAES 5288
Score = 116 bits (291), Expect = 8e-23
Identities = 145/673 (21%), Positives = 300/673 (44%), Gaps = 29/673 (4%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I +L+ + + K D++ N+R +++ K LE + + E
Sbjct: 6134 IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKI 6193
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + + K I +D++
Sbjct: 6194 KLETQHDR--QRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKD 6251
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-R 1749
+LE K LE ++L K ++LE++K++ A I+K L+K ++ + + +
Sbjct: 6252 MLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQIQKEREDLEKMNENITREMHEIK 6307
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLV 1581
QE+ MN + L+ I L +EL+KEK+ ++ L +
Sbjct: 6308 HQEEQMNQ--------------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQS 6353
Query: 1580 AAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
+ + +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+L+ K
Sbjct: 6354 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKL 6413
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTEN 1239
K + E E K LE+ + R +T + EEL+KE+ D + L E+
Sbjct: 6414 QKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED 6473
Query: 1238 GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+ EK ++ + E ++ L Q++ + K+ + K+ D+E + D
Sbjct: 6474 ---TKREKNSLDEMKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DK 6522
Query: 1058 QEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYST 879
E E+E+ L+A E+HK++ + E + +++ ER + V D+++ +
Sbjct: 6523 IRLREDELEQ-LQA-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIIS 6571
Query: 878 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDD 723
L+ + + D EAF NE++ L+ +K LE+ ++E T H+ EM +
Sbjct: 6572 LDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMET 6631
Query: 722 YNEAEKQTLKKRI------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 561
N KQ K ++ E+E+ + K L +D+ + ++ L+E+ NK +
Sbjct: 6632 MNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQM 6691
Query: 560 KQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPL 381
K LE+ E+ SK+++ R L + A + E L + RK L
Sbjct: 6692 KIGLEREADEI-SKIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVL 6741
Query: 380 DITKTCDAVDISE 342
D K + +++
Sbjct: 6742 DKIKVANESTLAD 6754
Score = 110 bits (275), Expect = 6e-21
Identities = 160/704 (22%), Positives = 306/704 (43%), Gaps = 60/704 (8%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAA 2262
EKDD ++ D + + L E+A+A +S+ ++++
Sbjct: 3517 EKDDLAHLAEDTKRKDDEMKVLH------ESALADIQKEKCNLEQMRESMFKQNEMIDSE 3570
Query: 2261 KQAL---ENKVGDFEAAIATLNDELLNEKDDKKCIV-NDRNIVEADKQALENKVADFEAT 2094
K+ + E+K+ +A I E+ D KK I+ N+R + Q L ++
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEM----DTKKSIIENERAAMTKKNQDLMTELTKQSED 3626
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ E+L EK+ ++E+D++ L+ V + + + + + K D++ + N++ +
Sbjct: 3627 VEIQMKEVLTEKE----LLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEV 3682
Query: 1913 LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---------LDKRISDLKAD 1761
L+ K L+ + ++E K E +R ++ I K + + I D+K
Sbjct: 3683 LKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQ 3742
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 3743 EKQMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL- 3781
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ +E+ + + +E+
Sbjct: 3782 -DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1248
L+ K K E EK LE K LER A + + +EE++ E+ +
Sbjct: 3841 LKMMKLQKQVF-------EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKM 3889
Query: 1247 TENGEGCE------AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
TE + + AE E+ +LD ++ SL LQ++ ++ + K+ D+
Sbjct: 3890 TEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDV 3949
Query: 1088 EAK--NASLTDNQEGH-EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL 918
+ K N L +++ G +AEI ++ E+ KEK + ES ER +
Sbjct: 3950 KNKKENLRLREDELGQLQAEIHKQQR--------EIEKEKSNIES----------ERAAI 3991
Query: 917 ESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDI 750
V D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T HD
Sbjct: 3992 IKIVEDLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDR 4051
Query: 749 E-------MKTGKDDDYNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDIN 618
+ T + D N ++T L ++ ++EE I SI +DK +K ++
Sbjct: 4052 QRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLE 4111
Query: 617 IWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 4112 KTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHE 4155
Score = 110 bits (275), Expect = 6e-21
Identities = 149/635 (23%), Positives = 281/635 (44%), Gaps = 43/635 (6%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
+++ +E + A+ V D ++ I +L+ + + K D++ N++ ++ K LE + +
Sbjct: 4843 EKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADE 4902
Query: 2105 FEAT-IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
E + T +D E+ + E DK + + + LN+ K+ K I
Sbjct: 4903 IEKIKLETQHDRQRVEEMTAQIQKERDK--INNLIEETNRKDMVLNEIKTEIKEKIKAIE 4960
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLND-------ELERKKDDNNAIIKKALDKRISDL 1770
+DR++LE K LE + L AK L E++++++D + +K I D+
Sbjct: 4961 SDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEK-FTIEIHDI 5019
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKT 1602
K Q Q+ D + L+ I L +EL+KEK+ D++
Sbjct: 5020 KHQEEQMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRS 5059
Query: 1601 ALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIR 1431
L DL +E K+ VN+I+ ++++ + L K+ EE+ + +E+ + +
Sbjct: 5060 QL--DLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSL 5117
Query: 1430 EEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSA 1251
+E+L+ K K L + E K LE+ +E R + I E EK+ + A
Sbjct: 5118 DEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK----EEIQNERQNLEKMTE-A 5172
Query: 1250 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
L E E E + + + +++ S + R+ + ++ + K+ D+E K
Sbjct: 5173 LKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK-- 5230
Query: 1070 LTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMET 891
+N E E+ R+L+A E+ KEK + ES ER + V D++
Sbjct: 5231 --ENLRLREDEL-RQLQAEIHKQQREIEKEKINIES----------ERAAIIKDVEDLQH 5277
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD--------IE 747
L+ + + D EAF NE++ L+ +K LE+ ++E T HD +
Sbjct: 5278 KIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQ 5337
Query: 746 MKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTEL 591
++ +D+ N E+ L ++ ++EE I SI +DK +K D+ SE+ ++
Sbjct: 5338 IQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKV 5397
Query: 590 QEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
+EDL K+ KE++DLEK +T ++ +
Sbjct: 5398 KEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 5432
Score = 110 bits (275), Expect = 6e-21
Identities = 135/650 (20%), Positives = 282/650 (43%), Gaps = 65/650 (10%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ + + + + + +ND + K+++K + D+ +E KQ +E + D
Sbjct: 5920 EKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHD 5979
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
F+ + +L+ +L K K+ E + + K+ + A + +
Sbjct: 5980 FDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKM 6039
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1806
+EL EK+ + D + IL+ K A E +ADL+ K+ L + E +
Sbjct: 6040 TEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDV 6099
Query: 1805 IKKALDKRISD-----LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1641
K + R+ + L+A+ ++ +E + + I+ N+E +
Sbjct: 6100 ENKKENLRLREDELWQLQAEIYKQQREIEKEKI--------NIESERAAIIKNVED---L 6148
Query: 1640 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE------ 1479
H+ + ++D + +L D A E + + ++ + LE ++ +++ L + D
Sbjct: 6149 QHKIISLDRDSE-SLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEM 6207
Query: 1478 ----VLERSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---- 1338
+R N I + R++ + EK+ ++ + + E EK LEKT
Sbjct: 6208 TAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSEL 6267
Query: 1337 -----VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEP 1179
LE++ N T+ I +E EK++++ E E E+Q +K + L+
Sbjct: 6268 YKVKEDLEKQKEN--TLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 6325
Query: 1178 TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLT 1005
I +L L+++ + +M + L++R S+L+ + ++ D E + E ++ K +
Sbjct: 6326 EIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 6385
Query: 1004 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 837
E+ KE+D+ ++S+ DL +K ++QV+E + + +E L E E
Sbjct: 6386 QKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEE 6445
Query: 836 FLNERDGLEAVKQGLEKRVLDLEATIHDI--------EMKTGKDDDYNEAEKQTLKKRIS 681
N+R LE + + L+K D+ D EMK + + +K+ K +
Sbjct: 6446 TQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKE--KSNLE 6503
Query: 680 ELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 531
E++E IS T+ +K I + E+ +LQ +++K+ E ++EK +E
Sbjct: 6504 EMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSE-TEIEKSNIE 6552
Score = 108 bits (270), Expect = 2e-20
Identities = 151/639 (23%), Positives = 281/639 (43%), Gaps = 55/639 (8%)
Frame = -2
Query: 2261 KQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL 2082
K+ L N + L +L++ + D K + DR E +K+A++ D + +
Sbjct: 5714 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 5773
Query: 2081 NDELLNEKDDKKCIVEADKQALESKVSVFEAAIAT-LNDELLNEKDDK-----KCIVNDR 1920
L + D++ + E Q + + + T D +LNEK+ K I +D+
Sbjct: 5774 EKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDK 5833
Query: 1919 NILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
++LE + LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 5834 DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM-NENITREMHEIKHQ 5892
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q +Q+ D + L+ I L +EL+KEK+ D++
Sbjct: 5893 EEQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQF- 5931
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ + + +++
Sbjct: 5932 -DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKD 5990
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-----EELRKEKVDK 1257
L+ K K E E K LE+ E R +T + EEL+KEK
Sbjct: 5991 LKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESF 6050
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1077
+ L E+ + E+ +LD + N++L DL + EK LE+ ++ +
Sbjct: 6051 THLAEDTK--------KEQEILD---KVKVANESLMADLQK---EKSNLEEMRENISKQT 6096
Query: 1076 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
+ + +E + +L+A E+ KEK + ES ER + V
Sbjct: 6097 EDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIES----------ERAAIIKNVE 6146
Query: 902 DMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEM 744
D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T HD +E
Sbjct: 6147 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 6206
Query: 743 KTG---KD-DDYNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSE 603
T KD D N ++T L ++ ++E+ I SI +DK +K D+ SE
Sbjct: 6207 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSE 6266
Query: 602 VTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 6267 LYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHE 6305
Score = 105 bits (263), Expect = 1e-19
Identities = 126/642 (19%), Positives = 281/642 (43%), Gaps = 46/642 (7%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLND-------ELLNEKDDKKCI-------VN 2160
+I +DR++LE K LE A L E+ E++D + + ++
Sbjct: 4958 AIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIH 5017
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
D E + ++++ + I L EL EK+ I+ D+ L+ + S +
Sbjct: 5018 DIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKE----IIMKDRSQLDLRQSELDKQQT 5073
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII- 1803
+ND + K+++K + D+ E KQ +E + D + ++ +L+++L+ K +
Sbjct: 5074 NVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLED 5133
Query: 1802 -KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
K L++ +L+ +A + + +E+ N + + N +L E
Sbjct: 5134 EKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDE 5193
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFLREEEDEV------ 1476
+ ++++ E + +++ +E+K +L+ E LR+ + E+
Sbjct: 5194 MKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQRE 5253
Query: 1475 LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAEKQGLE--KTVLER 1326
+E+ N+ AI+K + + + + ++D +S ++ E E EK+ L+ KT LER
Sbjct: 5254 IEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENEKEVLKQMKTELER 5312
Query: 1325 RASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQR 1146
A ++ + E + +++V++ A + E E D+ + N ++
Sbjct: 5313 EADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM--VLNEKNRDIEE 5368
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ + ++K LEK DLE + L +E E + E L E+ KE++D
Sbjct: 5369 KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA--------EIQKEREDLE 5420
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
E+I ++ +K + + + K +++ + + N Q+ + E + +R L+ +
Sbjct: 5421 KMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQS 5480
Query: 797 GLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 627
L+K+ + D+ T+ + + KD + E +KQ ++K ++++ L + KK+
Sbjct: 5481 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKL 5540
Query: 626 DINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 510
++ E +L++ +L +E+ E +++ +LEK
Sbjct: 5541 QKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 5582
Score = 104 bits (259), Expect = 4e-19
Identities = 127/622 (20%), Positives = 279/622 (44%), Gaps = 40/622 (6%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I L+ + + K D++ N++ +++ K LE + + E
Sbjct: 5261 IESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKI 5320
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + ++ K I +D++
Sbjct: 5321 KLETQHDR--QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5378
Query: 1916 ILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+LE K LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 5379 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKM-NENITREMHEIKHQE 5437
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIK 1590
Q +Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 5438 EQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL-- 5475
Query: 1589 DLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+
Sbjct: 5476 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQ 5535
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKT------VLERRASNLDTMDAIHEEELRKE---- 1269
+K K K E E K LE+ + E + ++ + EE +R++
Sbjct: 5536 KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLA 5595
Query: 1268 ------KVDKSALTEN---GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1116
K +K L E E A+ Q + + ++ I L + + + ++ +
Sbjct: 5596 HLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLRED 5655
Query: 1115 ALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNLTHNDELHKEKDDKE----SIMND 951
L+K ++++ + + + + E+E + E N+ EL K+ +D E I+ +
Sbjct: 5656 ELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMM--TELKKKSEDVEIQMKEILTE 5713
Query: 950 LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 771
+ + +R++L V +++ L + ++ D EAF NE++ ++ +K L+ + ++
Sbjct: 5714 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 5773
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE-VTE 594
E I+++T D E ++K ++ I T++ +L + N + E +
Sbjct: 5774 E----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE-ETNRKDMVLNEKNRDIEEKIKS 5828
Query: 593 LQEDLNKESKEKQDLEKRVLEL 528
+Q D + KE+ +LEK EL
Sbjct: 5829 IQSDKDMLEKERHNLEKTRSEL 5850
Score = 100 bits (250), Expect = 5e-18
Identities = 127/675 (18%), Positives = 292/675 (43%), Gaps = 46/675 (6%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ + +++++L K L+N+ + + ++ +++ +
Sbjct: 11957 ERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEE 12016
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N++ + + + + +R + + L+ ++ +F+A ++ +E
Sbjct: 12017 TRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEE 12076
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L ++ + K E K E+K ++ E +E+ EK+ ++ R +E ++
Sbjct: 12077 DLPKEKEMK---EDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKE 12133
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNAL 1722
+E + LE ++ ++ E ++ DD I K+ L+K S++ Q ++E +++
Sbjct: 12134 IEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKK 12193
Query: 1721 IXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK-----------DDKTALIKDLVAA 1575
I +IV L V + E+Q +K D++ LI++ +
Sbjct: 12194 IKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQ 12253
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEEL 1419
+ + E+ ++ + +LKE + +EE + V+E R +L M E+
Sbjct: 12254 QNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQK 12313
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI-----------HEEELRK 1272
+ + + L + E E+ + T L++R +T I +E+L++
Sbjct: 12314 QDLMNQRDLLKQ-----EREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQ 12368
Query: 1271 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1092
+ ++ E E + E + ++ D L+++ E++ L+K+ D
Sbjct: 12369 AIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADD 12428
Query: 1091 LEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAE 930
LE + D +E + + E+KL + +N L D+L KEK+D N+LD ++ E
Sbjct: 12429 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 12488
Query: 929 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEAT 762
Q ++++ +++ T E+ ++ E LN ER LE V+ EK +
Sbjct: 12489 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQ 12544
Query: 761 IHDIEMKTGKD-DDYNEAEKQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
I ++ +KT + D+ ++ + L +K ++ I +L + ++ +++ ++ EL
Sbjct: 12545 IEEMRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEEL 12601
Query: 590 QEDLNKESKEKQDLE 546
+ + K EK+DLE
Sbjct: 12602 KLEKQKIQNEKKDLE 12616
Score = 100 bits (248), Expect = 8e-18
Identities = 135/693 (19%), Positives = 298/693 (43%), Gaps = 107/693 (15%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ +E KQ +E + +
Sbjct: 6337 EKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDN 6396
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
+ + +L+++L K K+ I E + + K+ + A + +
Sbjct: 6397 MDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKM 6456
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------EL 1836
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++
Sbjct: 6457 AEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDI 6516
Query: 1835 ERKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXX 1698
E++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6517 EKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDA 6576
Query: 1697 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LE 1530
+ N + + + EL++E D+ + K + + ++ V E+ + +
Sbjct: 6577 ESLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMN 6633
Query: 1529 SKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQ 1353
++ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K
Sbjct: 6634 NERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKI 6693
Query: 1352 GLE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEA 1221
GLE K + NL+ M +A+ EE E++++ + E A
Sbjct: 6694 GLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLA 6753
Query: 1220 EKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA 1041
+ Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+
Sbjct: 6754 DLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIES 6813
Query: 1040 EIERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E + E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 6814 ERAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSI 6871
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK----- 732
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6872 ERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKER 6931
Query: 731 -----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 609
D+ Y E EK+ ++ S+LE+A S + K K+I I L
Sbjct: 6932 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIAL 6987
Query: 608 SEVTELQEDLNKESKE------KQDLEKRVLEL 528
+E+ + + L K SKE K + EK+ ++L
Sbjct: 6988 AEIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 7020
Score = 99.4 bits (246), Expect = 1e-17
Identities = 143/698 (20%), Positives = 299/698 (42%), Gaps = 53/698 (7%)
Frame = -2
Query: 2249 ENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL-NDE 2073
++++ + I L EL EK+ I+ DR+ ++ + L+ + + I T+ N+
Sbjct: 4167 QDELDQLKTEIQNLQQELEKEKE---IIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 4223
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L +KD ++ +E KQ +E + + +I +L+++L K K+ I ++N LE K
Sbjct: 4224 KLLDKDKEE--MEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFE 4281
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMNALI 1719
L+ + ++ K +E + + A+IK+ D + L A+ +R++E D+M
Sbjct: 4282 LQREADEIRKIKEETQNERQSLEKMTKALIKERED--LVHL-AEYTKREKEMLDEMQVA- 4337
Query: 1718 XXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 1539
+I+ + NI E+++ EK+ +L + + +
Sbjct: 4338 --NKSSMADLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEID 4395
Query: 1538 HLESKSRSLKEHFLREEEDEV--LERSASNLAI-MKAIREEELRKEKDGK---------- 1398
++ S + +RE+++ + L++ + ++ I MK I E+ E D
Sbjct: 4396 MEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLK 4455
Query: 1397 ---SALVENGEGCEAEKQ--GLEKTVLERRASNLDTMDAIHEEELRKEKV----DKSALT 1245
++ + E + +++ G EK VL++ ++L I +E+ K K+ D+ +
Sbjct: 4456 QKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQ----IQADEIEKIKLETQHDRQRVE 4511
Query: 1244 ENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR----VMAEKQALEKRCSDLEAKN 1077
E + ++ +++ LN+ + RD++ + ++K LEK +LE
Sbjct: 4512 EKTAQIQKDRDEINNLIVETNRKDMVLNE-MDRDIEEKIKSIQSDKDMLEKERHNLEKTR 4570
Query: 1076 ASLTDNQEGHEA--EIERK----------LEASNLTHNDELHKEKDD-----KESIMNDL 948
+ L +E E EIERK E + H +E K+K D K I N
Sbjct: 4571 SELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQ 4630
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
++ E++++ S ++ S L+ + D E NER L+ K+ E++ ++E
Sbjct: 4631 QELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEME 4690
Query: 767 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS-EVTEL 591
HD + D+ + + L+K++ E E K LK + I L E E+
Sbjct: 4691 KEKHDFDQSRKSLDE--DLKMMKLQKQVIEEE----------KSKLKQMKIELEREADEI 4738
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLEKCICGAR------DGLSTIKEAWMSDCMVPDNWV 429
++ + E+Q EK L + E A+ D + E+ ++D + +
Sbjct: 4739 RKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERS-- 4796
Query: 428 PFEDLVQGFSRKTSPLDITKTCDAVDISEDSTTNIQVD 315
+++ + S++T D+ + + + E+ +Q +
Sbjct: 4797 NLQEMRENISKQTE--DVENKKEKIRLREEKLKQLQAE 4832
Score = 99.4 bits (246), Expect = 1e-17
Identities = 138/664 (20%), Positives = 294/664 (44%), Gaps = 74/664 (11%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R+++E ++ + + + N +L+N++D K +R + L+ ++ +F
Sbjct: 11455 RSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLK---QEREEINHKWTQLQQRIDEF 11511
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+A ++ +E L ++ K + E K E+K+ + E T +++ EK+ ++ V
Sbjct: 11512 DAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVM- 11567
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
R +E K+ L+ + LE ++ ++ E ++ DD I K+ L+K S++ Q
Sbjct: 11568 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11627
Query: 1748 DQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEV-------NILILHEEL----QKEKDDK 1605
++E +++ I +IV L V +I + EEL QK D++
Sbjct: 11628 EEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQ 11687
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE---HFLREEED-------------EVL 1473
++++ + + E+ ++ + +LKE H +E+E+ E L
Sbjct: 11688 GLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDL 11747
Query: 1472 ERSASNLA-----------IMKAIREE------ELRKEKDGKSALVENGEGCEAEKQGLE 1344
E+ ++++ ++K REE +L++ D A V + + KQ
Sbjct: 11748 EKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQ--- 11804
Query: 1343 KTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 1170
K + E R S +T I E + + E K+ K E E A+ + ++ + ++ +
Sbjct: 11805 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLE 11864
Query: 1169 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHN 999
+ + + ++ +K+ +E+ DLE + + ++ E +E+E K+ + +
Sbjct: 11865 RVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKC 11924
Query: 998 D-ELHKE---------KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 849
D E KE ++ K I + + ERQ + + + S L NE ++ +
Sbjct: 11925 DIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKN 11984
Query: 848 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD-----DYNEAEKQTLKKRI 684
NE ER+ L+ ++ LEK ++++ E + K+D + +KQ L+ +
Sbjct: 11985 INEVIKKERETLKEMEAYLEKEKEEMKSITE--ETRRQKEDLEKMSTHINEQKQDLRSQR 12042
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVT-ELQEDLNKESKEKQD------LEKRVLELT 525
LE+ + K K+L + I+ + ++V+ + +EDL KE + K+D + +LE+
Sbjct: 12043 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK 12102
Query: 524 SKLE 513
+K E
Sbjct: 12103 TKAE 12106
Score = 98.2 bits (243), Expect = 3e-17
Identities = 142/710 (20%), Positives = 297/710 (41%), Gaps = 62/710 (8%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ ++ DR+ L+ + L+ + + + T + N+R L+ K+
Sbjct: 5464 EKEIIMKDRSQLDLRQSELDKQQTNMNDIMET--------------MKNERKQLDKDKEE 5509
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE--------- 2100
+E + + E ++ + +D+K + + + E +K LE + E
Sbjct: 5510 MEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKI 5569
Query: 2099 --------ATIATLNDELLNEKDD----------KKCIVEADKQALESKVSVFEAAIATL 1974
+ + +EL+ EK+ +K I++ K A ES ++ + + L
Sbjct: 5570 KEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL 5629
Query: 1973 NDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 1794
+ N K+ I N++ + + L+ +++ ++ ++ E + + A+I++
Sbjct: 5630 EEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREK 5689
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
+++LK + D E M ++ + V NL+ ++ L + ++ K
Sbjct: 5690 -QNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLK 5746
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV---LERSASNLAIM 1443
D+ A + A + K + +E + R EE ER N I
Sbjct: 5747 LDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIE 5806
Query: 1442 KAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---------VLERRASNLDT 1305
+ R++ + EK+ ++ + + E E+ LEKT LE++ N T
Sbjct: 5807 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN--T 5864
Query: 1304 MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEPTIPSLNDALQRDLDRV 1131
+ I +E EK++++ E E E+Q +K + L+ I +L L+++ + +
Sbjct: 5865 LAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 5924
Query: 1130 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----K 969
M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D +
Sbjct: 5925 MKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSR 5984
Query: 968 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 789
+S+ DL +K ++QV E + + +E L E + E NER LE + + L+
Sbjct: 5985 KSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELK 6044
Query: 788 KRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILTDKAK 639
K + E+ H E T K+ + NE A+ Q K + E+ E IS T+ +
Sbjct: 6045 K---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVE 6100
Query: 638 KLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 489
+++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 6101 NKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 6147
Score = 94.7 bits (234), Expect = 3e-16
Identities = 125/616 (20%), Positives = 275/616 (44%), Gaps = 31/616 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGD-------FEAAIATLNDELLNEKDDKKCIVNDRNIVEA 2139
S+ + ++ K+ L+ + D FE I + EL E ++ I + +E
Sbjct: 2366 SLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAEN---IERKKKELEI 2422
Query: 2138 DKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDE-- 1965
K A+ + E + +E D+ + + AD +E + S ++ E
Sbjct: 2423 QKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEES 2482
Query: 1964 -LLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1800
+ EKD K N++N+ L A + L+ + A++E K L + ++R + + I K
Sbjct: 2483 YVKKEKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITK 2542
Query: 1799 KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1620
+ +R+++++ + +++ D+ + ++E + IL+ EL+K
Sbjct: 2543 EK--QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEK 2588
Query: 1619 EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMK 1440
K+ KT L ++ A + K + + + L L ++E E E+ ++ +
Sbjct: 2589 IKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDR 2642
Query: 1439 AIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD 1260
EE + K ++ K + + + E+ L + +R S+ DT++ +L K K +
Sbjct: 2643 RNNEEMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTE 2700
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK 1080
L + + E Q + + +E I + L++ + +K+ LEK E +
Sbjct: 2701 MKDLEK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKE 2753
Query: 1079 NASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSD 900
A ++ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E +
Sbjct: 2754 KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 899 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDD 726
+E + ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D+
Sbjct: 2814 IE----QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDE 2866
Query: 725 DYN--------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDL 579
+ N E+++ TL+K +L++ + + D K+L + I L+E+ + +E L
Sbjct: 2867 EANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREIL 2926
Query: 578 NK----ESKEKQDLEK 543
+ SK+K+DLEK
Sbjct: 2927 EQLKLTLSKQKEDLEK 2942
Score = 94.4 bits (233), Expect = 4e-16
Identities = 147/772 (19%), Positives = 322/772 (41%), Gaps = 64/772 (8%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
K D++ + N++ +L+ K L+ + + E I DR L+
Sbjct: 3670 KQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMN 3729
Query: 2258 QALENKVGDF---EAAIATLNDELLNEKDD----KKCIVNDRNIVEADKQALENKVADFE 2100
+ ++ D E + DEL K + ++ + ++ I+ D+ L+ K ++ +
Sbjct: 3730 DNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELD 3789
Query: 2099 ATIATLNDELLNEKDDKKCI------VEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ND + K+++K + +E K+ +E + F+ +L+++L K K+
Sbjct: 3790 KQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQ 3849
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
++N LE K LE + ++ K + +E +++L+K +LK
Sbjct: 3850 VFEEEKNKLEQMKIELEREAGEIRKIKEEIQNE------------RQSLEKMTEELK--- 3894
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
R++E + +I+ ++V L ELQKEK + + +++
Sbjct: 3895 --REKESFTHLA--------EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK 3944
Query: 1577 AEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERS------ASNLAIMKAIREEELR 1416
+ E + E + L+ +++ + E+S A+ + I++ ++ + +
Sbjct: 3945 QTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIIS 4004
Query: 1415 KEKDGKSALVENGEGCEAEKQGLE--KTVLERRASNL----------------------- 1311
++D +S ++ E E E++ L+ KT LER +
Sbjct: 4005 LDRDAESLKLDR-EAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITK 4063
Query: 1310 --DTMDAIHEEELRKEKV--DKS--------ALTENGEGCEAEKQGPEKTVLDLEPTIPS 1167
D ++ + EE RK+ V +K+ ++ + + E EK EKT +L
Sbjct: 4064 ERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELY----K 4119
Query: 1166 LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELH 987
+ + L++ + +AE ++K DLE N ++T +E + H +E
Sbjct: 4120 VKEDLEKQKENTLAE---IQKEREDLEKMNENIT-------------IEMHEIKHQEEQM 4163
Query: 986 KEKDD-----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER 822
K+K D K I N ++ E++++ S+++ S L+ + D E NER
Sbjct: 4164 KQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 4223
Query: 821 DGLEAVKQGLEKRVLDLEATIHDIEMK-TGKDDDYN--EAEKQTLKKRISELEEAISILT 651
L+ K+ +E++ ++E +++ D+D + +KQ +++ ++LE+ L
Sbjct: 4224 KLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4283
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIK 471
+A ++ K +E L++ KE++DL + E T + ++ + D +
Sbjct: 4284 READEIRKIKEETQNERQSLEKMTKALIKEREDL-VHLAEYTKREKEML----DEMQVAN 4338
Query: 470 EAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISEDSTTNIQVD 315
++ M+D + E++ + S++T DI + + ED +Q +
Sbjct: 4339 KSSMADLQREKRIL--EEMRENISKQTE--DIENEKEKSKLREDELKKLQTE 4386
Score = 94.4 bits (233), Expect = 4e-16
Identities = 139/601 (23%), Positives = 252/601 (41%), Gaps = 10/601 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR-------NIVEADKQAL 2124
+N +E K+ L+N + E + +L E N +D+K + R N + +++ L
Sbjct: 9390 KNQIEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDL 9449
Query: 2123 ENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVF--EAAIATLNDELLNEK 1950
EN + E + +E + ++ I + D + +S+ ++ E I +ELL K
Sbjct: 9450 ENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMK 9509
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL 1770
+ + + +E Q L+ DLE AK E++R++D II + ++ ++
Sbjct: 9510 VE---MGRTKEEIEKESQRLQDATIDLENAKA----EIQRQEDKFEDIIDIKIQEKEREI 9562
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1590
K Q D+E + V +LE+ + + + Q+ +D K L K
Sbjct: 9563 KI---QLDKETKRLS------------EEIELKVKDLEMEMADMKRQKQEIEDTKGLLEK 9607
Query: 1589 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ K+ + + LE + L RE+++ ER+ NL +K + E+LRKE
Sbjct: 9608 E-------KQELKQEKKELEDQMMDLT----REKQETEEERN--NLMALKN-QLEDLRKE 9653
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ EK LEK+ +E + ++++ + K +K +L +
Sbjct: 9654 NE-----------IVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRFE 9702
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
E +KQ E + + + D L R+L + K LEK + N+E
Sbjct: 9703 TEQQKQMLEISTTKMMEEKNEMAD-LSRELQKA---KDELEK---------IAYKTNKER 9749
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 870
HE E +++A ELH + + ++ + Q+++ K + +E ++
Sbjct: 9750 HEVE---QMQA-------ELHSQ----------IQAIEQQGQIMQDKQNHLEEKELSIQR 9789
Query: 869 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKK 690
+ ++ N F E++ L V + KR DLE DIE+ K N + + L+K
Sbjct: 9790 KEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEK 9845
Query: 689 RISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLE 513
SELE D+ IW + L E L + KEK+ LEK +EL SK E
Sbjct: 9846 IRSELENE-----------KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKRE 9894
Query: 512 K 510
+
Sbjct: 9895 Q 9895
Score = 94.4 bits (233), Expect = 4e-16
Identities = 135/648 (20%), Positives = 285/648 (43%), Gaps = 52/648 (8%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVE--------- 2142
I +RN LE K L + E + L+ ++ +K I ++ IVE
Sbjct: 10201 IEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQ 10260
Query: 2141 -------ADKQALENK-VADFEATIATLNDELLNEKDDKKCIVEADK------QALESKV 2004
++ ALE + + D + +A EL N+ + + + EA K + E+ +
Sbjct: 10261 RNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHL 10320
Query: 2003 SVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN---DELE 1833
+ I ++ +E +K+D + I N+ KQ L+ K LE + +N + +
Sbjct: 10321 QRDKKEIKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQ 10377
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1653
++ D+ +A ++K ++ +++ K +R +++N I ++
Sbjct: 10378 QRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHE---INQKIE 10434
Query: 1652 NILILHEELQKEKDDKTAL-IKDLVAAEPGKRTVNEIV---SHLESKSRSLKEHF-LREE 1488
+ L E++ KEK+ A+ IK + E + +E+V + ++ + + L + + E+
Sbjct: 10435 ELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQ 10494
Query: 1487 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1308
E E LE+ S + K E+E R E D K + + EK +EK+ +
Sbjct: 10495 EKEDLEKMKSEIMTQKQEMEKE-RSELDNKI------QQTDLEKHDIEKSKEIVEKLMFE 10547
Query: 1307 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL--------DLEPTIPSLNDAL 1152
+ HE +L+KE++D E +K E+ +L + I ++N+ +
Sbjct: 10548 VEEQRHEIQLQKEELD----------IERQKIADEQDLLIQNKSELQNENERIRNINEVI 10597
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 972
+++ + + + LEK +++ S+T+ + ++E K+ N +L K++D
Sbjct: 10598 KKERETLKEMEAHLEKEKEEMK----SITEETRRQKEDLE-KMSTDIKEQNQDLMKQRDL 10652
Query: 971 KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 792
E D++H E L+ ++ + + + ++ + ++ + + ER LE K
Sbjct: 10653 LEQEKEDINH---EWTQLQQRIDEFD---AQVSKQKEEDLTKQKEMKEERKSLEETK--- 10703
Query: 791 EKRVLDL--EATIHDIEMKTGKDDDYN------EAEKQTLKKRISELEEAISILTDKAKK 636
R++++ +A + DI+ + K+++ E + + L + SEL+ S + + KK
Sbjct: 10704 -ARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKK 10762
Query: 635 LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK-----LEKC 507
L D I E L++ ++ K++Q +E+ EL +K +EKC
Sbjct: 10763 LNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKC 10810
Score = 92.8 bits (229), Expect = 1e-15
Identities = 132/673 (19%), Positives = 297/673 (44%), Gaps = 31/673 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENK-------VGDFEAAIATLNDELLNE----KDDKKCIVNDR-N 2151
++N R++LE ++ + +K + +F+A ++ ++ L + K+D+K + + N
Sbjct: 10924 LMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 10983
Query: 2150 IVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN 1971
++E +A ++ + N+E E+++ + IVE +++ L S E + ++
Sbjct: 10984 VIEMKTKAEPEEIKKEKEKE---NEEEEEEEEEIRVIVETERKELYQIKSELERVRSEID 11040
Query: 1970 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE-----LERKKDDNNAI 1806
E D K I ++ LE K + + +E ++ L+++ LE+ + +
Sbjct: 11041 HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKE 11100
Query: 1805 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1626
I + L + + + D + +E D+ E N+L+ ++
Sbjct: 11101 IVEKLMVEVEEQRKDIQLQKEELDIERQKIAD-----------------EQNLLVQNKAK 11143
Query: 1625 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS---RSLKEHFLREEEDEVLERSASN 1455
+ ++++ + + + E + T+ E+ HL+ + RS+ E R +ED LE+ +++
Sbjct: 11144 LQNENERIKKVDEEIKKE--RETLREMEIHLKKEKEELRSIIEETQRRKED--LEKMSTD 11199
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR 1275
+ K L+ ++D L+E E E+ E T L++R D + E+L
Sbjct: 11200 INEQKL----HLKNQRD----LLEQ----EREEINHEMTQLQQRIDEFDAQVSKQREDLT 11247
Query: 1274 KEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCS 1095
K+++ E E++ E+T + + + +L +M EK+ ++
Sbjct: 11248 KQEM------------EEERKSLEETKARI------IEMKTKAELQEIMQEKEEEDEE-- 11287
Query: 1094 DLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLE 915
E + + +E ++ + E K S + H E K DDK+ I + + ++ + +
Sbjct: 11288 --EMRVIVEMEREELNQIKSELKRVRSEIDH--EQKKLNDDKKIIEQEKEDLEKMKSEIM 11343
Query: 914 SKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 735
++ ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 11344 TQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQ 11403
Query: 734 KDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
K D N+A+ Q +RI E++E I K K+ LK++ L + E + +
Sbjct: 11404 KIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSVIE 11459
Query: 572 ES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFS 399
E+ ++K+DLEK ++ +K + + RD L +E + W + + F
Sbjct: 11460 ETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDEFD 11512
Query: 398 RKTSPL---DITK 369
+ S D+TK
Sbjct: 11513 AQVSKQKEEDLTK 11525
Score = 92.8 bits (229), Expect = 1e-15
Identities = 128/675 (18%), Positives = 276/675 (40%), Gaps = 35/675 (5%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N R++LE ++ + +++ + I + ++ +++D + + + E K E K
Sbjct: 11209 NQRDLLEQEREEINHEMTQLQQRIDEFDAQVSKQRED----LTKQEMEEERKSLEETKAR 11264
Query: 2108 DFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEKDD 1944
E E++ EK+++ + IVE +++ L S + + ++ E DD
Sbjct: 11265 IIEMKTKAELQEIMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDD 11324
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDKRI 1779
KK I ++ LE K + + +E ++ L++ +LER +N+ I + L ++
Sbjct: 11325 KKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKV 11384
Query: 1778 SDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTA 1599
+ + D + +E D+ E QK D++
Sbjct: 11385 EEQRKDIRLQKEELDI---------------------------------ERQKIADEQGL 11411
Query: 1598 LIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
++++ + + E+ ++ + +LKE E L
Sbjct: 11412 VVQNKAKLQNENERIKEMDEEIKKEKETLKE------------------------MEAHL 11447
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---DAIHEE-----------E 1281
RKEK+ +++E E +K+ LEK + N D M D + +E +
Sbjct: 11448 RKEKEEMRSVIE--ETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQ 11505
Query: 1280 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1101
R ++ D + E +K+ E+ E I + + + +++ EK+ E+
Sbjct: 11506 QRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEE- 11564
Query: 1100 CSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV 921
E A + +E + +I+ +LE + E K DDK+ I + + ++ +
Sbjct: 11565 ----EVMRAKVEMKKEELD-QIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSE 11619
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
+ + ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 11620 IMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIE 11679
Query: 740 TGKDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 579
K D N+A+ Q +RI E++E I K K+ LK++ L + E +
Sbjct: 11680 RQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSV 11735
Query: 578 NKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQG 405
+E+ ++K+DLEK ++ +K + + RD L +E + W + +
Sbjct: 11736 IEETQRRQKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDE 11788
Query: 404 FSRKTSPL---DITK 369
F + S D+TK
Sbjct: 11789 FDAQVSKQKEEDLTK 11803
Score = 91.7 bits (226), Expect = 3e-15
Identities = 140/737 (18%), Positives = 310/737 (42%), Gaps = 97/737 (13%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ +V+++ +L + L+NK + D+ +++ +
Sbjct: 10274 ERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEE 10333
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N + K+ K + +R + + ++ +F+A + +E
Sbjct: 10334 TSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEE 10393
Query: 2072 -LLNEK---DDKKCIVEADKQALESK---------VSVFEAAIATLNDELLNEKDDKKCI 1932
L N+K +++KC+ E + + +E K ++ + TL ++++ EK+ + +
Sbjct: 10394 DLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAM 10453
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADA 1758
L+ ++ L+ ++L KT ++ E ++ DD I K+ L+K S++
Sbjct: 10454 TIK---LKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10510
Query: 1757 PQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD------KTA 1599
+ ++E +++ I +IV L + E+Q +K++ K A
Sbjct: 10511 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIA 10570
Query: 1598 LIKDLVAAEPGK--------RTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIM 1443
+DL+ + R +NE++ + ++ H +E+E+ M
Sbjct: 10571 DEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEKEE------------M 10618
Query: 1442 KAIREEELRKEKDGKSA----------LVENGEGCEAEKQGL--EKTVLERRASNLDTM- 1302
K+I EE R+++D + L++ + E EK+ + E T L++R D
Sbjct: 10619 KSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQV 10678
Query: 1301 ------DAIHEEELRKEKVD----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
D ++E+++E+ K+ + E E E EK + E + +
Sbjct: 10679 SKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 10738
Query: 1151 QRDLDRVMAE-------------------------KQALEKRCSDLEAKNASLTDNQEGH 1047
++LDR+ +E KQ LEK S++ + + + +
Sbjct: 10739 GKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSEL 10798
Query: 1046 EAEIERK-LEASNLTHNDELHKE-----KDDKESIMNDLDHVKAERQVLESKVSDMETTY 885
E +I++ +E ++ ++ E+ ++ ++ K I + + ERQ + + +
Sbjct: 10799 ENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 10858
Query: 884 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------D 723
S L NE ++ + NE ER+ L+ ++ LEK+ ++++ E + K+D D
Sbjct: 10859 SELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSE--ETRRLKEDLEKMSTD 10916
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQD-- 552
N+ K + +R LE+ + K K+L + I+ + ++V++ +E DL KE K+D
Sbjct: 10917 VNKQNKDLMNQR-DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRK 10975
Query: 551 ----LEKRVLELTSKLE 513
+ V+E+ +K E
Sbjct: 10976 SLEETKANVIEMKTKAE 10992
Score = 91.3 bits (225), Expect = 4e-15
Identities = 146/692 (21%), Positives = 284/692 (41%), Gaps = 60/692 (8%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQAL---ENK 2241
+R LE LE K + + I +NILE K L + +
Sbjct: 13577 ERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQ 13636
Query: 2240 VGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNE 2061
V + + T+ + +E ++ +C+ RN +E +K+++ ++++ + I L E+ +E
Sbjct: 13637 VQQQKHEMETIRKTMKSEMENLECL---RNELEDEKKSMLSRLSMEKHEIDKLKTEIQSE 13693
Query: 2060 KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYK 1881
K+ +E +K+ L+ E+ L++ + DK I +++ LE K L+ K
Sbjct: 13694 KES----IEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRK 13749
Query: 1880 VADLE-----AAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIX 1716
L+ A + T + K D++ ++ L +D++ A + E D+ L
Sbjct: 13750 AEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQA--KILESDVQLLQT 13807
Query: 1715 XXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNE 1548
+ +LE N L L +EL+KEK +I D+ + +
Sbjct: 13808 EKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------D 13859
Query: 1547 IVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGE 1374
V+ L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 13860 AVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENM 13918
Query: 1373 GCEAEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTE 1242
+ + ++ + E R D + DA+ + +EL K D E
Sbjct: 13919 KMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKE 13978
Query: 1241 NGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA---- 1083
+ E E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 13979 HVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADD 14038
Query: 1082 --------KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH 942
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 14039 IKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQ 14098
Query: 941 ---------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGL 792
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +
Sbjct: 14099 KEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 14158
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 612
E +EKQ++++ +EL K+L +++ +
Sbjct: 14159 E-------------------------SEKQSIERERAEL-----------KRLKEEVEVQ 14182
Query: 611 LSEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
E T LQ+D N KEK+ LE T ++
Sbjct: 14183 -HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 14213
Score = 90.1 bits (222), Expect = 8e-15
Identities = 141/644 (21%), Positives = 275/644 (42%), Gaps = 49/644 (7%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN- 2118
I NDR E L+N+ D E + + DE N + K+ + +DR+ +E ++ LE
Sbjct: 2638 IDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKT 2697
Query: 2117 --KVADFEATIATLND-------ELLNEKD---DKKCIVEADKQALESKVSVFEAAIATL 1974
++ D E + + + E+ E++ K + K+ LE + FE A +
Sbjct: 2698 KTEMKDLEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1973 N-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERK--KDDNNAI- 1806
+ E L E+ +K+ I D+ + ++ E + L K N+EL+++ +D+ + I
Sbjct: 2758 SLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE 2815
Query: 1805 -IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1638
IK L K D + ++D E+D ++ + + E N+ +L
Sbjct: 2816 QIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVL 2873
Query: 1637 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSA 1461
+ L+ ++D L K+ + + ++ LES++R + ++E E+LE+
Sbjct: 2874 KQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1460 SNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1290
L+ K E+E KEK S E E ++E++G+ KT R MD
Sbjct: 2931 LTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIKKEMD--- 2981
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL 1110
EL++ +++ EN E +KQ ++ + D++ K L
Sbjct: 2982 --ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKIEQIKAEL 3018
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDKESIMNDL 948
+K D E + + ++ +E + ++ +E S DE + K+ + +D
Sbjct: 3019 QKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDR 3078
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
D ++ ER LE ++M L ++++Q ER+ LE +K L K+ DLE
Sbjct: 3079 DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLE 3138
Query: 767 ATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL------TDKAK 639
E + +D ++E++ +K+ + ELE+ L + K
Sbjct: 3139 KERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQK 3198
Query: 638 KLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 510
K+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3199 KIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 89.0 bits (219), Expect = 2e-14
Identities = 139/671 (20%), Positives = 284/671 (42%), Gaps = 55/671 (8%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R I+E ++ L + + + ++ E DDKK I ++ +E K + +
Sbjct: 11290 RVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQM 11349
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALES---KVSVFEAAIATLNDELLNEK----DD 1944
E + L D + + D ++ +E K+ ++ KV I +EL E+ D+
Sbjct: 11350 EEERSEL-DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADE 11408
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISD 1773
+ +V ++ L+ + ++ +++ K TL + L ++K++ ++I++ ++ D
Sbjct: 11409 QGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKED 11468
Query: 1772 LK---ADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
L+ D +++Q+ L+ + L+ I ++ K+K++
Sbjct: 11469 LEKMSTDVNKQNQD-----LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED- 11522
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE---EEDEV-----------LERS 1464
L K E K + +E K+++ E +E EE+EV L++
Sbjct: 11523 -LTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQI 11581
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIH 1290
S L +++ + E +K D K + + E E K + ++ +E S LD + I
Sbjct: 11582 KSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELD--NKIK 11639
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDLEPT--------IPSLNDALQR 1146
+ +L + ++ S E E+Q + K LD+E + LQ
Sbjct: 11640 QTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQN 11699
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ +R+ + ++K L+ A L +E E+ +E + ++L K D
Sbjct: 11700 ENERIKEMDEEIKKEKETLKEMEAHLRKEKE----EMRSVIEETQRRQKEDLEKMSTDVN 11755
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
+ +MN D +K ER+ + K + +LQQ++D+ +A ++++ + KQ
Sbjct: 11756 KQNQDLMNQRDLLKQEREEINHKWT-----------QLQQRIDEFDAQVSKQKEEDLTKQ 11804
Query: 797 G-LEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD 624
+E+ LE T I IEMKT + + + EK+ E EE + + K+ L
Sbjct: 11805 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE------KEEEEVMRAKVEMKKEELDQ 11858
Query: 623 INIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I L SE+ Q+ LN + K EK+DLEK E+ + ++ + + I++
Sbjct: 11859 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 11918
Query: 467 AWMSDCMVPDN 435
++ C + ++
Sbjct: 11919 TYIEKCDIENS 11929
Score = 88.2 bits (217), Expect = 3e-14
Identities = 144/674 (21%), Positives = 290/674 (43%), Gaps = 38/674 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
K + VV + E KQ +E++ E A + I DR E
Sbjct: 2984 KQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMV 3043
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD--------------KQALE 2121
L+N+ D E + + DE N + K+ + +DR+ +E + K+ LE
Sbjct: 3044 IKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLE 3103
Query: 2120 NKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN-DELLNEKDD 1944
+++ E + + E + K + K+ LE + FE A ++ E L E+ +
Sbjct: 3104 SQIRQHEIQLVEIQKER-EILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSE 3162
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKA 1764
++ I N R ++ LE +L AK N+EL++K II+ DK I +KA
Sbjct: 3163 REGIDNTRTRIKQEMDELEKTRQNL--AKEQENNELQKK------IIEDERDK-IEQIKA 3213
Query: 1763 DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+ + ++ + + N N+ +L+K++++ +L ++L
Sbjct: 3214 ELKKEAEKTKLE-------------------LQNERQNLEEAGTKLKKDRENVESLAEEL 3254
Query: 1583 VAAE---PGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRK 1413
+ + E+ ++ ++E L E L+++ +++A K E +L +
Sbjct: 3255 GRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTDIAGAKEDLENQLLE 3309
Query: 1412 EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-EELRKEKVDKSALTENG 1236
E++ V+ E +AEK L L ++ + +D +++ E+LR +V+ L
Sbjct: 3310 EREKNK--VKQAE-IQAEKDML---YLLKQGISEQQVDIVNKTEQLRLREVELEQLQALI 3363
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMA----EKQALEKRCSDLEAKN 1077
+ E + K +++ + + D LQR+++++M ++ LEK S++ A+
Sbjct: 3364 YRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSEMIAQK 3423
Query: 1076 ASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDM 897
+ IE + + N T+ E+ +++ E M +L + K Q ++K+ M
Sbjct: 3424 HQMDIELNKERGLIEERTQMLN-TYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQM 3482
Query: 896 ETTYSTLNNELQQKMDD----NEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
+ ELQ++ DD E NER LE + + LEK DL D + K +
Sbjct: 3483 KI-------ELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLAEDTKRKDDEM 3535
Query: 728 DDYNE---AEKQTLKKRISELEEAI-----SILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+E A+ Q K + ++ E++ I ++K K +L++ ++ ++Q ++N+
Sbjct: 3536 KVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILRE-----DKLQQMQAEINR 3590
Query: 572 ESKEKQDLEKRVLE 531
+ E D +K ++E
Sbjct: 3591 QQTE-MDTKKSIIE 3603
Score = 88.2 bits (217), Expect = 3e-14
Identities = 131/622 (21%), Positives = 266/622 (42%), Gaps = 27/622 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVG-------DFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD 2136
I+ R +E + L+NK+ D E + + ++ ++ +K I + ++ +
Sbjct: 11067 IMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIE 11126
Query: 2135 KQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLN 1956
+Q K+AD + + +L NE + K + E K+ E+ + + L
Sbjct: 11127 RQ----KIADEQNLLVQNKAKLQNENERIKKVDEEIKKERET--------LREMEIHLKK 11174
Query: 1955 EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDK 1785
EK++ + I+ + + K+ LE D+ K L ++ LE+++++ N + + L +
Sbjct: 11175 EKEELRSIIEET---QRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQ-LQQ 11230
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
RI + DA Q +D+ I + + + +E ++E +++
Sbjct: 11231 RIDEF--DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEE 11288
Query: 1604 TALIKDLVAAEPG--KRTVNEIVSHLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAI 1434
+I ++ E K + + S ++ + + L + + E+E E LE+ S + +
Sbjct: 11289 MRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQ 11348
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
EEE R E D K +++T LER +++ I ++ + K + +
Sbjct: 11349 MEEE-RSELDNK----------------IKQTDLERH--DIENSKEIVQKLMVKVEEQRK 11389
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 1074
+ E + E+Q + D + + LQ + +R+ + ++K L+ A
Sbjct: 11390 DIRLQKEELDIERQ----KIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEA 11445
Query: 1073 SLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KESIMNDLDHVKAERQVLESKV 906
L +E E+ +E + ++L K D + +MN D +K ER+ + K
Sbjct: 11446 HLRKEKE----EMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKW 11501
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG-LEKRVLDLEAT-IHDIEMKTGK 732
+ +LQQ++D+ +A ++++ + KQ +E+ LE T I IEMKT
Sbjct: 11502 T-----------QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKT 11550
Query: 731 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKESK 564
+ + + EK+ E EE + + K+ L I L SE+ Q+ LN + K
Sbjct: 11551 EPEKIKKEKE------KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKK 11604
Query: 563 ----EKQDLEKRVLELTSKLEK 510
EK+DLEK E+ + ++
Sbjct: 11605 MIEQEKEDLEKMKSEIMKQRQQ 11626
Score = 87.8 bits (216), Expect = 4e-14
Identities = 143/649 (22%), Positives = 278/649 (42%), Gaps = 45/649 (6%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEA---AIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N+++ ++ E K + + A+ +N EL + + K + + EAD Q +NK
Sbjct: 13558 NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTE 13617
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
+ + + EL EK V+ K +E+ ++ + L + L NE +D+K +
Sbjct: 13618 ELKNILEREKSELYQEKAQ----VQQQKHEMETIRKTMKSEMENL-ECLRNELEDEKKSM 13672
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDKRISDLKADA 1758
R L K ++ ++++ K ++ +E L++ KD+N + + LD I + D
Sbjct: 13673 LSR--LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENES-KRTQLDNTIEKMNMDK 13729
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
+E D +I ++L+ L EE++K + + +D
Sbjct: 13730 LSIQREKD----------------SLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKI 13773
Query: 1577 AEPGKRTVNEIVS---HLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ + E+ S +E +++ L+ L + E E+LE+S + +++ E+L K+
Sbjct: 13774 LDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLR----EDLEKQ 13829
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ ++ EK LE+ + + D + ++ E K+ K+ TE E
Sbjct: 13830 RKRNDLTLQE---LRKEKMALEQMITD-ITKEKDAVASLQNEVSLKQHELKNKETELDE- 13884
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+++ + + LE S N Q+++D + E K +DLE+ L + +
Sbjct: 13885 ---QRKEMDDLRMQLEMRQNSTNKQ-QQEVDVFIVENM---KMRNDLESMKTLLDEERRQ 13937
Query: 1049 HEAEIERKLEASNLTH---------NDELHKEKDDKESIMNDLDHVKAERQ---VLESKV 906
+ I+ + N+ H DEL K D I + +HV+ ER+ VL ++
Sbjct: 13938 LQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD---IKTEKEHVEKEREEIDVLNKEI 13994
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE--MKTGK 732
+ +LN E+ E F E G A + LE+ DL A DI+ ++T K
Sbjct: 13995 IKSKEELQSLNLEI-------EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEK 14047
Query: 731 DDDYNEAEKQT-------LKKRISELEEAIS-------------ILTDKAKKLLKDI-NI 615
+ EK+T L+K+ +ELEE + I+ DK +K ++DI +
Sbjct: 14048 QMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTV 14107
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
SE L+++ ++ +K L ++V +LE+ + RD + K+
Sbjct: 14108 IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKK 14156
Score = 87.4 bits (215), Expect = 5e-14
Identities = 127/646 (19%), Positives = 279/646 (43%), Gaps = 58/646 (8%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
++ KQ ++ K A+ L K+ ++ I ++ +E +K ++ + +
Sbjct: 9910 IQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKV 9969
Query: 2093 IATLNDELLNEKDDKKCIVEAD----KQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
+ E + + +K I EAD K+ E+ E + +++ N ++ K +
Sbjct: 9970 L-----EEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQ 10024
Query: 1925 DRNILEAAKQALEYKVADL-----------EAAKTTLNDELERKKDDNNAIIKKA--LDK 1785
+R ++ KQ L+ + DL E +K +L++E + + N I+++ L+K
Sbjct: 10025 ERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEK 10084
Query: 1784 RISDL-----KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE--- 1629
D+ K D Q + +++ A+ K LE ++ ++EE
Sbjct: 10085 EKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGD 10144
Query: 1628 ---LQKEKDDKTALIKDL-VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE-VLERS 1464
++ + + + I+++ V A+ ++ +++I S LE + + + D ++E+
Sbjct: 10145 LEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKE 10204
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDTMD--- 1299
++L MK+ + ++ +D +S L + + EK +EK ++ER + ++
Sbjct: 10205 RNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDF 10264
Query: 1298 AIHEEELRKEK---VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-------Q 1149
+ +EEL E+ VD+ L CE E Q + + ++E + + + L Q
Sbjct: 10265 KLKKEELALERQNIVDEKYLLAQ---CETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 10321
Query: 1148 RD-------LDRVMAEKQALEKRCSDLEAKNASLT---DNQEGHEAEIERKLEASNLTHN 999
RD ++ +K+ LEK + + + L D E EI K +
Sbjct: 10322 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 10381
Query: 998 DELHKEKDDKESIMNDLDHVKAERQVLES---KVSDMETTYSTLNNELQQKMDDNEAFLN 828
+ + + KE + + ++ ER+ LE K+ +M+T ++E+ QK+++
Sbjct: 10382 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEE------ 10435
Query: 827 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 648
L+ +++ + K EA ++M E++ L + SEL + +
Sbjct: 10436 ----LQTLQEQIMKEKEKAEAMTIKLKM-----------EREDLDQIKSELVREKTEVDH 10480
Query: 647 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
+ KKL DI + E +L++ ++ +KQ++EK EL +K+++
Sbjct: 10481 EQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 10526
Score = 85.5 bits (210), Expect = 2e-13
Identities = 144/713 (20%), Positives = 299/713 (41%), Gaps = 118/713 (16%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
++N R++L+ ++ + +K + I + ++ +K++ + + + E K E K
Sbjct: 11483 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED--LTKQKKMEEERKSLEETK 11540
Query: 2114 VADFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEK 1950
+ E T +++ EK+ + + VE K+ L+ S E + ++ E
Sbjct: 11541 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11600
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDK 1785
DDKK I ++ LE K + + +E ++ L++ +LER +N+ I + L
Sbjct: 11601 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMV 11660
Query: 1784 RISDLKADAPQRDQE---------DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
+ + + D + +E D+ ++ ++ ++ L E
Sbjct: 11661 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKE 11720
Query: 1631 ---ELQKEKDDKTALIK----------------------DLVAAEPGKRTVNEIVSHL-- 1533
L+KEK++ ++I+ DL+ + E ++H
Sbjct: 11721 MEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWT 11780
Query: 1532 --------------ESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGK 1398
+ K L + EEE + LE + + MK E E+++KEK+ +
Sbjct: 11781 QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE 11840
Query: 1397 SALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEE--------LRKEKVD---- 1260
V + E +K+ L+ K+ LER S +D HE++ + +EK D
Sbjct: 11841 EEEVMRAK-VEMKKEELDQIKSQLERVRSEID-----HEQKKLNDDKKMIEQEKEDLEKM 11894
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDL---EPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
KS + + + E E+ E + + I + + +Q+ + V +K ++ + +L
Sbjct: 11895 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 11954
Query: 1088 EAKNASLTDNQE---GHEAEIER------------KLEASNLTHNDE-LHKEKDDKESIM 957
+ + + D Q+ +++E++ K E L + L KEK++ +SI
Sbjct: 11955 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 12014
Query: 956 N-------DLD----HVKAERQVLESKVSDMETTYSTLNN---ELQQKMDDNEAFLNER- 822
DL+ H+ ++Q L S+ +E +N+ +LQQ++D+ +A ++++
Sbjct: 12015 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 12074
Query: 821 -DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDK 645
+ L K+ E R E + +EMKT + + + EK+ E E+ + + +
Sbjct: 12075 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEK-----EEEEQEMRVKVEM 12129
Query: 644 AKKLLKDINIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEK 510
+K ++ I L SE+ Q+ LN + K EK+DLEK E+ + ++
Sbjct: 12130 ERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQ 12182
Score = 85.1 bits (209), Expect = 3e-13
Identities = 128/613 (20%), Positives = 259/613 (42%), Gaps = 34/613 (5%)
Frame = -2
Query: 2261 KQALENKVGD-FEAAIATLNDELLNEKDDKKCIVN-DRNIVEADKQALENKVADFEATIA 2088
KQ + K+ D + + + D + + K ++ +++ +E K ++ ++ +FE +
Sbjct: 14661 KQPIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNME 14720
Query: 2087 -TLND---------ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
TL + +LL++KDD ++ + +E+ F+ IA L + K DK+
Sbjct: 14721 ETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE 14780
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAA------------KTTLNDELERKKDDNNAIIKKA 1794
I N+ L+ +Q E + + + KT L D E+KK D ++ +K
Sbjct: 14781 NIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLK-- 14838
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
++D AD+ + D E + L + V L EEL E
Sbjct: 14839 ----LTD--ADSAKTDGEREAQTL-----------ETKVQDVLQLTDYTTQDQEELHDEM 14881
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAI 1434
++K +I +L A+ + + L+ + RS +E + E LER ++L
Sbjct: 14882 ENKMKIILELNEAK-------KDLQKLKEECRSAEEE--KSVIMESLERRRNSL------ 14926
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLERRASNLDTMDAIHEEELRKEKVDK 1257
E+++ E + +++ + E Q +E K ++ R+ + ++ ++
Sbjct: 14927 --EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQGQEATETT 14984
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPS----LNDALQRDLDRVMAEKQALEKRCSDL 1089
+T+ E + K+ + TV LE T+ S + D+L ++++ V K ++ L
Sbjct: 14985 GHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQL 15044
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD----HVKAERQV 921
E + + E E +E +E + + ++L + DKE + N LD ++ +
Sbjct: 15045 EQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKLLQLTHDKEDLSNTLDKKNKEIENNTET 15103
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
K++ +ETT + + K+ +E +L L+ T + E++
Sbjct: 15104 SLKKIAQLETTIVLMKKD---------------------KENIENELLQLKQTEQEREIQ 15142
Query: 740 TGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 564
G DD NE EK K +ELE+ + KK +D ++ L++ + D +E++
Sbjct: 15143 RGTDDTSNEREKYDEKVTYKTELED-----NKEKKKPDRDSSLKLTDADSAKTDGEREAQ 15197
Query: 563 EKQDLEKRVLELT 525
+ + VL+LT
Sbjct: 15198 TLETKVQDVLQLT 15210
Score = 84.0 bits (206), Expect = 6e-13
Identities = 125/589 (21%), Positives = 252/589 (42%), Gaps = 18/589 (3%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDEL-LNEKDDKKCIVNDRNIVEADKQALENKVADFE- 2100
+E KQ ++N+ + A L +E NE+ +++ + N + A + + DFE
Sbjct: 7151 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQKVN-QQKQATAFQMEKTDFER 7209
Query: 2099 --ATIATLNDELLNEKD-DKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
I N EL ++++ +KK I E K+ TL + N + I
Sbjct: 7210 IKTEIDQANKELADQQEKNKKTITEMQKER------------ETLEEMRANISKQVETIT 7257
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA-LDKRISDLKADAPQ 1752
N+ L + + L D+ L + E + N +++ LD+R SD+ D Q
Sbjct: 7258 NENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQ 7309
Query: 1751 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAE 1572
++ +D M+ ++N+E L + + + K D +L + A E
Sbjct: 7310 KEVDDLMD--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACE 7355
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
+ +NE +E + L ++ ++D++ ++R NL + K + E ++ + K
Sbjct: 7356 QLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKI 7415
Query: 1394 ALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGE 1233
+L G + +EK E+ ++E A+ LD + E + +E++D++
Sbjct: 7416 SLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKT 7475
Query: 1232 GCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE 1053
+ EKT DL+ T +N D + + ++ L K
Sbjct: 7476 YYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK----------------- 7512
Query: 1052 GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 873
E E +++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + +
Sbjct: 7513 --EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMM 7567
Query: 872 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ--- 702
E + D E NE+D L+ ++ ++K + +L+ E + + N+ +Q
Sbjct: 7568 KEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTE 7621
Query: 701 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 561
+K + L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7622 EIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7670
Score = 84.0 bits (206), Expect = 6e-13
Identities = 115/623 (18%), Positives = 262/623 (42%), Gaps = 6/623 (0%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
+ L E+ ++ K ++++ I +++ Q L + + L E+ N K DK +
Sbjct: 8809 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNL 8868
Query: 2039 VEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA 1860
E K LE K E+ L E + KK I ++ +E +++ +E ++ + E
Sbjct: 8869 -EKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVK 8927
Query: 1859 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 1680
T ++++ K++ + ++ L K+ + + D + M L
Sbjct: 8928 GFT---DVQKYKEELQIVTEELLTKKRN---LEQLNSDVQHLMQTLEEVDIQYIKKKAEL 8981
Query: 1679 XKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF 1500
I S ++ IL E+ +K+ ++ +I+++ + ++N + KE+
Sbjct: 8982 EHITSEIQKREQIL-EKQKKKLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENL 9040
Query: 1499 LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRA 1320
RE+++ L R EL++++D VE+ ++ K ++ +
Sbjct: 9041 RREKQETELFRG-------------ELQRQRDE----VESSRQALIMEKDQFKLKIDHQR 9083
Query: 1319 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1140
+ + A +E R E ++ + + E+ + +E + + + L ++
Sbjct: 9084 NEMSA--AFEKEHKRLENMENDLENQRAKLAESLNDAAK-----MEQKLQQMKNELNKEK 9136
Query: 1139 DRVMAEKQALEKRCSDLEAKNASLTDN----QEGHEAEIERKLEASNLTHNDELHKEKDD 972
++V KQ ++ +E + + ++GHE ++++K E + D+L ++ +
Sbjct: 9137 EQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANS 9190
Query: 971 KESIMNDLD-HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG 795
+ + DL ++ +RQ +E ++MET +L+ ++ DD N+RD E
Sbjct: 9191 ESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTH 9250
Query: 794 LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 615
LE + +L D+E K + + +E K+ ++ + LE + K + K++
Sbjct: 9251 LELKREELVRETEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMEN 9310
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPD 438
SE +L ++ +LE RV +E L++ + + E MS+ + +
Sbjct: 9311 VHSERQKLLLLQGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTE 9368
Query: 437 NWVPFEDLVQGFSRKTSPLDITK 369
+ L++ R+ L+I+K
Sbjct: 9369 Q-NEYRKLIEELQREKEQLEISK 9390
Score = 84.0 bits (206), Expect = 6e-13
Identities = 140/656 (21%), Positives = 289/656 (44%), Gaps = 72/656 (10%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
IA + D+LL EK+D + N + + +++++ D + + N +LL K +
Sbjct: 13412 IADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTE---- 13467
Query: 2039 VEADKQALESKVSVFEAAIATLNDELL---NEKDDKKCIVNDRNILEA-AKQALEYKVAD 1872
++ ALE + + +N ++ E++ + ++ + E A+ ++ + D
Sbjct: 13468 IQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 13527
Query: 1871 LEAAKTTL----------NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMN 1728
+E+ K L N EL+ + ++ +IKK ++ + K + QR+++ + MN
Sbjct: 13528 IESVKVRLVTESNQIDKMNSELKTRSEELENLIKK--QQKEFETKENEMQRERKALEKMN 13585
Query: 1727 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG-----K 1563
A + + N + + +LQKEK +KT +K+++ E K
Sbjct: 13586 AELERKSTE----------LKNKIEKVTVWEADLQKEK-NKTEELKNILEREKSELYQEK 13634
Query: 1562 RTVNEIVSHLESKSRSLKEHF-----LREEEDEVLERSASNLAIMK-------------- 1440
V + +E+ +++K LR E ++ + S L++ K
Sbjct: 13635 AQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQSEK 13694
Query: 1439 -AIREE-----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA------ 1296
+I EE +L+ E + K ++N EK ++K ++R +L+ + A
Sbjct: 13695 ESIEEEKKTLKQLKDENESKRTQLDN----TIEKMNMDKLSIQREKDSLEEIKADLQRKA 13750
Query: 1295 -IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1119
+EE+RK S ++++ + + +++ E+ + + I L+ D+ + EK
Sbjct: 13751 EKLDEEMRKAVQITSQISQDAKILDDDRE-KEEELRSMRADIERQAKILESDVQLLQTEK 13809
Query: 1118 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
+ LEK S T+N E ++E++ + ++LT EL KEK E ++ D+
Sbjct: 13810 EILEK----------SKTENDLLRE-DLEKQRKRNDLT-LQELRKEKMALEQMITDITKE 13857
Query: 938 KAERQVLESKVSDMETTYSTLNNEL---QQKMDDNEAFLNER-DGLEAVKQGLEKRVLDL 771
K L+++VS + EL +++MDD L R + +Q ++ +++
Sbjct: 13858 KDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVEN 13917
Query: 770 EATIHDIE-MKTGKDDDYNEAEKQTLKKRISELEEAISIL----------TDKAKKLLKD 624
+D+E MKT D+ E++ L+ I E+ ++L TD+ +K D
Sbjct: 13918 MKMRNDLESMKTLLDE-----ERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 13972
Query: 623 INIWLSEVTELQED---LNKE-SKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I V + +E+ LNKE K K++L+ LE+ ++ I G R + ++++
Sbjct: 13973 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEI-EMFKQEIAGKRAQIESLEQ 14027
Score = 83.6 bits (205), Expect = 8e-13
Identities = 137/630 (21%), Positives = 251/630 (39%), Gaps = 35/630 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN 2118
++V + E KQ +E++ E A L E + + ++ I NDR E L+N
Sbjct: 2792 NVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQN 2851
Query: 2117 KVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ D E + + DE N + KQ LES E L KD +K
Sbjct: 2852 EKKDIETSTDRIRDEEAN--------LRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEK 2903
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+ + E ++ + LE K TL+ + E + + + K+ D IS +
Sbjct: 2904 QLESQNRQHEIQLAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKAD--ISLREELQ 2961
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNIL---ILHEELQKEKDDKTALIKD 1587
Q ++E + +V LE N L I+ +E K + K L K+
Sbjct: 2962 EQSEREGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKE 3021
Query: 1586 LVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSASNLAIMKAIREEELRKE 1410
E +R + E R+ +E ++ + E + +E S IR+EE E
Sbjct: 3022 AEDTEKQRRDI-------EKDRRNNEEMVIKLQNEKKDIETSTDR------IRDEEANLE 3068
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSA------- 1251
K L + + E E+ LEKT E I + E++ ++ K
Sbjct: 3069 VQ-KQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLK 3127
Query: 1250 --LTENGEGCEAEKQGPEKTVLDLEPT-----------IPSLNDALQRDLDRVMAEKQAL 1110
L++ E E E+ EK D+ + I + +++++D + +Q L
Sbjct: 3128 INLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNL 3187
Query: 1109 EKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
K + E + + D ++ E AE++++ E + L EL E+ + E L
Sbjct: 3188 AKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKL----ELQNERQNLEEAGTKL--- 3240
Query: 938 KAERQVLESKVSDMETTYSTLNN-----ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 774
K +R+ +ES ++ L N E+Q+K +++ + ER +E L+K V D
Sbjct: 3241 KKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTD 3295
Query: 773 LEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 603
+ D+E + ++ + N +AE Q K + L++ IS + + + E
Sbjct: 3296 IAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVE 3355
Query: 602 VTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ +LQ + ++ E + K ++ +LE
Sbjct: 3356 LEQLQALIYRQQDEIEANRKAIINEKYRLE 3385
Score = 79.7 bits (195), Expect = 1e-11
Identities = 110/587 (18%), Positives = 242/587 (41%), Gaps = 7/587 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
RN +EA K +EN+ + + D + K ++ + +++ + L KV
Sbjct: 14077 RNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQRE 14136
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + L ++ ++ ++ K I+E++KQ++E + A + L +E + + ++ + D
Sbjct: 14137 QEELERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEE-VEVQHERTLLQQD 14191
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR-- 1749
+N+++ K+ LE + A L +E++RK + + + K+ KR + P+
Sbjct: 14192 KNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIE 14251
Query: 1748 -----DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+EDD+ ++ + +E+ K + + +++
Sbjct: 14252 IEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEET 14311
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
VA + V ++ L S+ + +++H L LA MK I + E + K
Sbjct: 14312 VATTAKQPIVIKLEDTLTSEVQEMRDH---------LNNEIKELARMKTIMKMEKDQLKQ 14362
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE 1224
KS + E E + +E+ + E+ + + H++E +DK + E
Sbjct: 14363 AKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDK-----KNKEIE 14414
Query: 1223 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE 1044
+ K + LE TI + + + ++ KQ ++R +++ K A +T
Sbjct: 14415 NNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQER--EIQRK-ADVTST----- 14466
Query: 1043 AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL 864
E+++ +T+ EL +D KE I D D E +S +D E TL ++
Sbjct: 14467 ---EKEMYTEKVTYKTEL---EDSKEKIKPDRDST-LELTDTDSAKTDGEREAQTLETKV 14519
Query: 863 QQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI 684
Q + + +++ L + K +L+L D+ Q LK+
Sbjct: 14520 QDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDL---------------QKLKEEC 14564
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 543
EE S++ + ++ + SEV L ++++ ++ K ++++
Sbjct: 14565 RSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQ 14611
Score = 77.8 bits (190), Expect = 4e-11
Identities = 127/620 (20%), Positives = 259/620 (41%), Gaps = 70/620 (11%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQA---LESKVSVFEA 1989
D+ + A+ Q L ++ + L E+ K+ I++ D++ L+ +V
Sbjct: 1361 DQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKE----IMKRDREEIRLLKIEVQRRRR 1416
Query: 1988 AIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD-NN 1812
I ++++ E+D+ + + + + ++ LE ++ ++ ND +E+ ++D NN
Sbjct: 1417 EIEYREEKIMREQDELELM---SKMGQRQREELEERLEEVIKE----NDRVEQMREDVNN 1469
Query: 1811 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
A+ K +D+ D++ QE A++ I S + L L
Sbjct: 1470 AL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKS-YRASDLELSA 1526
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 1452
+QKE+ + K+++ E K +N+I +++ +E ++ E+E E +
Sbjct: 1527 SIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKLHEEEK-EMKTKRV 1582
Query: 1451 AIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------EKTVLERR------ 1323
++ R+ + KEK+ G A+ + KQ L EK+ LE +
Sbjct: 1583 SLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIK 1642
Query: 1322 -------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE------- 1203
AS D +I E + +++ ++ + C E+Q E
Sbjct: 1643 QVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDE 1702
Query: 1202 ------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+T D+E + L++ D + K ++K DL+ + A +
Sbjct: 1703 LSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREK 1762
Query: 1058 QEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAERQVLESKVSDMET 891
+E E+E+ + N D E K E D K ++ + ++++A+R+++E + +E
Sbjct: 1763 EEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALEN 1822
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM------KTGKD 729
L E +ER +E + L++ +LE HD++ + KD
Sbjct: 1823 MKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKD 1882
Query: 728 -DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWLSEVTELQEDLNKE 570
++ E + TL K S++ E IS L + K +++ I I ++ ++Q DLN++
Sbjct: 1883 LENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQ 1942
Query: 569 SKEKQDLEKRVLELTSKLEK 510
KE QD++ V S+L+K
Sbjct: 1943 QKEMQDIQNAVFMEKSELKK 1962
Score = 76.6 bits (187), Expect = 1e-10
Identities = 135/691 (19%), Positives = 273/691 (39%), Gaps = 100/691 (14%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R ++E K+ALEN + + + N D+++ + N ++ + + LE K D
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + T + + ++ + + E +++K V E I+ LN + +KD+
Sbjct: 1870 QQ-LQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQ---QKDE------- 1917
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
+E K ++ + DL+ +T LN + + +D NA+ K L K ++ A Q
Sbjct: 1918 ---IENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQL 1971
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAE 1572
Q DM NL+ I+ ++LQ E+D L ++L + +
Sbjct: 1972 KQVGDMMQFTQNEK-------------DNLDRERAAIIEQKLQMERDMTHLLNRELESLK 2018
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
K+ V LE SL E+ ++ LER + + + EE K +
Sbjct: 2019 LVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQ 2078
Query: 1394 ALVENGEGCE----AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK---------- 1257
L E+ E AEKQ LE +E + + M+ E + ++E VDK
Sbjct: 2079 TLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEI 2138
Query: 1256 ------------SALTENGEGC---------------EAEKQGPEKTVLDLEPTIPSLND 1158
+A+ EN + E+Q ++ V ++E +L D
Sbjct: 2139 TFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-D 2197
Query: 1157 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER----KLEASNLTHNDEL 990
+Q ++D+ E+Q +E + +LE + + L ++++ + E+ + E + N EL
Sbjct: 2198 EMQMEVDK---ERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLEL 2254
Query: 989 HKEKDDKESIMNDLD---------------------------------HVKAERQVLESK 909
E KE + +L+ ++A++ K
Sbjct: 2255 QSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKK 2314
Query: 908 VSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
++T L+++ + E+ E + +E K+ + ++ E+ + +EM+
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM 2374
Query: 728 DDYNEA----------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV------T 597
Y E ++Q +K I ++ + I + ++ K++ I V
Sbjct: 2375 KKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYML 2434
Query: 596 ELQEDLNKESK--EKQDLEKRVLELTSKLEK 510
E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2435 ETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 76.3 bits (186), Expect = 1e-10
Identities = 149/734 (20%), Positives = 298/734 (40%), Gaps = 87/734 (11%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDR----NILEAAKQALEN 2244
+++ LE K ++ ++ +FE + +++D+ N L+ + +EN
Sbjct: 14697 EKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIEN 14756
Query: 2243 KVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALE---------NKVADFEATI 2091
F+ IA L + K DK+ I N+ ++ +Q E N+ +++ +
Sbjct: 14757 ITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKV 14816
Query: 2090 ATLNDELLNEKDDKK-------CIVEADK---------QALESKV-SVFEAAIATLND-- 1968
T EL + K+ KK + +AD Q LE+KV V + T D
Sbjct: 14817 -TYKTELEDSKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLTDYTTQDQE 14875
Query: 1967 ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1788
EL +E ++K I+ + N + Q L+ + E K+ + + LER+++ + + L
Sbjct: 14876 ELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLS 14935
Query: 1787 -----KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH-EEL 1626
++ +K + Q + + + + + E ++ I +E
Sbjct: 14936 LTQEIDHLAQIKTEMQQIEIKMQIQT---------------RSVATQWETDVQIQQGQEA 14980
Query: 1625 QKEKDDKTALIKDLVAAEPGKR-TVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLA 1449
+ T ++ ++A+ K+ TV ++ L S+ + +++ +E ED +A
Sbjct: 14981 TETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMED---------VA 15031
Query: 1448 IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE 1269
MK I + E + + KS + E E + +E+ + E+ + + H++E
Sbjct: 15032 RMKTIMKMEKDQLEQAKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSN 15088
Query: 1268 KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
+DK + E + K + LE TI + + + ++ KQ ++R ++
Sbjct: 15089 TLDK-----KNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQER--EI 15141
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA----ERQV 921
+ ++ +E ++ ++ K E L N E K D + D D K E Q
Sbjct: 15142 QRGTDDTSNEREKYDEKVTYKTE---LEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQT 15198
Query: 920 LESKVSDM-----ETT--YSTLNNELQQKM----DDNEA-----FLNER----------- 822
LE+KV D+ +TT L++E++ KM + NEA L E+
Sbjct: 15199 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVI 15258
Query: 821 -DGLEAVKQGLEK---RVLDLEATI-HDIEMKTGKDDDYNEAEKQT------------LK 693
+ LE + LEK VL L I H ++KT + ++QT ++
Sbjct: 15259 MESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVATQWETDVQIQ 15318
Query: 692 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ E E +T K+++ + VT+L++ L E +E +D + +E +++
Sbjct: 15319 QEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVERMK 15378
Query: 512 KCICGARDGLSTIK 471
+ +D L K
Sbjct: 15379 TMMKMEKDQLEQAK 15392
Score = 72.8 bits (177), Expect = 1e-09
Identities = 142/713 (19%), Positives = 290/713 (40%), Gaps = 73/713 (10%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ + NDRN+L+ + L+ K+ SI D L+ K+A
Sbjct: 6846 EKELLHNDRNLLKKDVEDLQQKL---------------------MSIERDSESLKLDKEA 6884
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE---ATIATL 2082
EN+ + A+ + +L + D+ + I + ++Q +E K A + I TL
Sbjct: 6885 FENE----KEAMKQMKTDLQIQADEIEKIKLE---THHERQRVEEKTAQIQKEREEINTL 6937
Query: 2081 NDELLNEK---DDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
+E+ ++ D+ + +K+A+ES S E A + + N + I RN L
Sbjct: 6938 VEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNAL 6997
Query: 1910 EAAKQALEYKVADLEAAKTTL---NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE 1740
E + + LE K + +ELER D ++A D +S + ++ + E
Sbjct: 6998 EKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQR-QQEAKDHLLSGITDESLLKKSE 7056
Query: 1739 DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKR 1560
+ ++ +S+ + + + + E D K AL KD + +
Sbjct: 7057 AE---IVLQPSQVDKAKPARKTEISDSDKQPVFVQQ--MPEMDLKDALKKDFESEKLDLP 7111
Query: 1559 TVNEIVSHLESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGK 1398
V +++ + + L++ + +E D++ L++ A + K + E +K D
Sbjct: 7112 KVKDVLP--QDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMA 7169
Query: 1397 SALVE------------NGEGCEAEKQG----LEKTVLERRASNLDTMDAIHEEELRKEK 1266
+ L E N + +KQ +EKT ER + +D + ++ K K
Sbjct: 7170 ARLQEERRTNERLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNK 7229
Query: 1265 VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND------ALQRDL-----------D 1137
+ + + E E + K V + SL+ LQ D+ +
Sbjct: 7230 KTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKN 7289
Query: 1136 RVMAEKQALEKRCSD---LEAKNASLTDNQEGHEAEIER-KLEASNLTHN--DELHKEKD 975
+M E L++R SD L+ + L D + A +ER +LE T N ++ K
Sbjct: 7290 TIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKM 7349
Query: 974 DKES-------IMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 816
+KE+ + + D ++ ER++L + + + EL+ + E NE+
Sbjct: 7350 EKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKE 7409
Query: 815 LEAVKQGLEKRVL----------DLEATIHDIEMKTGKDDDYNE--AEKQTLKKRISELE 672
LE +K L+++ + D + ++ + + D +E AE + +++R+ + E
Sbjct: 7410 LEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTE 7469
Query: 671 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ K +K +++ E T+LQ+ + + +++++ ++ EL + E
Sbjct: 7470 K-------KRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKE 7515
Score = 71.2 bits (173), Expect = 4e-09
Identities = 110/577 (19%), Positives = 245/577 (42%), Gaps = 27/577 (4%)
Frame = -2
Query: 2189 EKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALES 2010
EK ++ + +N+ ++L + + + + +L E+++ + I+ + +E
Sbjct: 13018 EKQKEEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRME- 13076
Query: 2009 KVSVFEAAIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1833
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 13077 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 13134
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1659
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 13135 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 13176
Query: 1658 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1479
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 13177 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 13236
Query: 1478 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 1305
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 13237 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 13292
Query: 1304 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 13293 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 13350
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDE--LHKEK 978
+ ++ + +K L+ S+L + L D E++ + E S DE L +E+
Sbjct: 13351 EESMNEMTKKKSELQHERSELYKQKQQLED-MIASESKRDVDTERSRQDKEDEQILKRER 13409
Query: 977 DD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 810
++ K+ ++ + + V+ ++ + + +E S LN++ ++ +N+ L + ++
Sbjct: 13410 EEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQ 13469
Query: 809 AVKQGLEKRVLDLE-------ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILT 651
LEK + DL+ A + + + + D E K+ K +E++ +
Sbjct: 13470 VKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIE 13529
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+L+ + N ++ ++ +L S+E ++L K+
Sbjct: 13530 SVKVRLVTESN----QIDKMNSELKTRSEELENLIKK 13562
Score = 68.6 bits (166), Expect = 3e-08
Identities = 127/670 (18%), Positives = 270/670 (40%), Gaps = 78/670 (11%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
+R LE K AL+++ + E ++ E + + + + +E KQ +EN+ A+
Sbjct: 12819 ERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAE 12878
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
E + + ++ K ++ + + Q E V + T+ DEL +++
Sbjct: 12879 LEIDLENI---IIETKSKQERLESIEVQLQEKNVQM-----GTILDELNKRQEE------ 12924
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
L+A K + + + + DEL I+K+ +++ + + ++D
Sbjct: 12925 ----LDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKD 12980
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE----------LQKEKDDKTAL 1596
Q +M A + +E++ L+L+ E L+K+K++ +
Sbjct: 12981 QFGNMQAELQKGQL-------------EMEMHQLMLNSERDELNGMRVNLEKQKEEFELM 13027
Query: 1595 IKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVLERSASN 1455
++L + P K+ V E+ + L + + E R E+ + +E
Sbjct: 13028 QQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKT 13087
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT-MDAIHE--E 1284
I A EE +KE D + + E CE ++ + + L + + +D D I + +
Sbjct: 13088 KQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEIDIERDEIQKLRK 13143
Query: 1283 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA----------LQRDL-- 1140
+ KEK + + + + E EK E ++ I SL + LQ L
Sbjct: 13144 QYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKLRE 13203
Query: 1139 -----DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEA------------- 1017
D + EK LEK+ +++E DN + E K+EA
Sbjct: 13204 AENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNYLE 13263
Query: 1016 ---SNLTHND---------------ELHKE-KDDKESIMNDLDHVKAERQVLESKVSDME 894
NLT EL+K+ K+ +E M+ ++ +AER+ +E + +M
Sbjct: 13264 QMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERVMDEMA 13323
Query: 893 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY-- 720
+ + E ++ ++ E +R LE + K+ +L+ ++ + + +D
Sbjct: 13324 EEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLEDMIA 13383
Query: 719 NEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+E+++ +R + +E IL + +++ + L E +++ + ++EK+ +EK
Sbjct: 13384 SESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKM 13443
Query: 539 VLELTSKLEK 510
+L + E+
Sbjct: 13444 QSQLNDQKEE 13453
Score = 66.2 bits (160), Expect = 1e-07
Identities = 120/590 (20%), Positives = 242/590 (41%), Gaps = 46/590 (7%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
+R + A+ Q + ++ T+ + DE+ + ++ + + L K ++ E
Sbjct: 8091 ERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKNM-EKTYE 8149
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL----------NDELER 1830
NDE+ EK I + + +L + LE ADLE K + N+ LER
Sbjct: 8150 QQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLER 8206
Query: 1829 KKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1671
+K D II+ +A +R ++ A A +RD E+ M + +
Sbjct: 8207 EKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQEASKNQMV 8265
Query: 1670 --------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH---LESK 1524
+ L+ ++L EL+K K D + DL ++T +EI+ H +SK
Sbjct: 8266 ELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKHEKDTDSK 8319
Query: 1523 SRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENGEGCEAEK 1356
+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 8320 TRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM----------- 8367
Query: 1355 QGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEKQGPEKTV 1194
K V+ +R D M+ I EE+ +E+ + L N + + + +
Sbjct: 8368 ----KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERT 8419
Query: 1193 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEAS 1014
+LE ++ D++R++ E + + +L+ E+ER++E S
Sbjct: 8420 ANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EMERRMEKS 8460
Query: 1013 NLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTLNNELQQK 855
+ DE K + + + D+ ++ L ++ ++E + L + Q++
Sbjct: 8461 KV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQ 8519
Query: 854 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 675
E ER+ LE +K + + D+E +E K++ + Q K+ + +
Sbjct: 8520 ESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSV 8579
Query: 674 EEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 528
E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8580 TE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8625
Score = 65.9 bits (159), Expect = 2e-07
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -2
Query: 1565 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1389
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1388 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1209
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1208 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1029
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1028 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 900
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 899 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 723
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 564
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 563 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 399
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 398 RKTSPLDITKT-----CDAVDISEDST 333
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.9 bits (159), Expect = 2e-07
Identities = 125/657 (19%), Positives = 260/657 (39%), Gaps = 68/657 (10%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
I ++ +E++K L + D E A L + DK+ ++ + ++E +K +
Sbjct: 8155 IQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKI 8214
Query: 2114 VADFEATIATLNDELLNE------KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNE 1953
+ + E+ E E +D ++ + + + ++E + + L ++
Sbjct: 8215 IENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQEASKNQMVELKRQIDKL 8274
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---------------ELERKKDD 1818
+ K ++ + L+ K L+ ++ DLE ++ + E++R+KDD
Sbjct: 8275 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 8334
Query: 1817 NNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-- 1656
I+K L+KR + L+++ ++D + M +I +
Sbjct: 8335 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 8394
Query: 1655 -VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSRSLK--- 1509
+ IL +Q + D +TA ++D +A +R V E+V + R+LK
Sbjct: 8395 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVRNLKGEM 8453
Query: 1508 EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLEKTVL 1332
E + + + E+ E+ I + I++ ++R+ G +E + E + + +
Sbjct: 8454 ERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 8513
Query: 1331 ERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT-VLDLE 1182
E++ + +H+E E+ +EK D E E +++ E T + +
Sbjct: 8514 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 8573
Query: 1181 PTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1011
+ S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +K E
Sbjct: 8574 EELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-KKGEQLL 8632
Query: 1010 LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 831
DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8633 EKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDLFRSELQ 8692
Query: 830 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------------ 687
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8693 RQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKIRFDIAN 8749
Query: 686 ----ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 528
I + + IL D + +D + E +L E D+E+ VLE+
Sbjct: 8750 ARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLVLEV 8802
Score = 64.3 bits (155), Expect = 5e-07
Identities = 123/636 (19%), Positives = 256/636 (40%), Gaps = 49/636 (7%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E AK +++ + E + DE+ E + K I + ++ DK ALE + D
Sbjct: 453 IEQAKVDIQSHMISMEGRV----DEIKRETERLKHIKTE---MQRDKDALEKQKDDTRKA 505
Query: 2093 IATLND---ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLND----ELLNEKDDKKC 1935
E++ E+ + + ++ ++ LE+ A + +ND ++L EK++
Sbjct: 506 KEEAERKRYEIVTEELEHRARLQRERDELEN----IRAEMQRVNDVEKAKILKEKEES-- 559
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAP 1755
+ R ++ E A+++A K LN E + I +RI A
Sbjct: 560 -IRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEI------ERIKHETLRAK 612
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
+ + E+ + I + ++E + EE+QK K+ +L
Sbjct: 613 E-EIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKV----EEIQKTKEQMEEAKVELEEE 667
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEED-------------EVLERSASNLAIMKAI 1434
++VS ++ L+ LR +E+ E+ ++ L ++ +
Sbjct: 668 REDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLEKL 727
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
REE R +K+ + + +E L K L++ ++ + ++ + K +
Sbjct: 728 REETERSQKNIEESKIE---------LMLWKESLDKLKGEMEEDKHVVIMQMNEAKAKEE 778
Query: 1253 ALTENGEGCEAEKQ----GPEKTVLDLEPTIPSLNDALQR------DLDRVMAEKQALEK 1104
LT E E E+ EK +L+ I + + LQR D RV+ K+ E
Sbjct: 779 QLTMVIEQLEIERGEITISREKVKEELDE-INRMRNELQRQHAEMEDWFRVV-NKEKEEA 836
Query: 1103 RCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDELHKEKDDKESIMNDLDHVKAE- 930
+ L A + ++ E+E R ++ L DE+ K+ ++ E I ++ + E
Sbjct: 837 NLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAEELEQINKEIQRARQEL 896
Query: 929 -----------RQVLESKVSDMETTYSTLNNELQQKMDDNEAFL---NERDGLEAVKQGL 792
+++LE + + L+ K D ++ +ER LE ++ +
Sbjct: 897 EKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSERKELEQMRFQV 956
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL---EEAISILTDKAKKLLKDI 621
E DLE +++ + + +K+ L+K S+L E+++ + A++ +
Sbjct: 957 ENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKA 1016
Query: 620 NIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ + E+ E +ED+NK +E + E+ + L +E
Sbjct: 1017 ELLIVEIQEQREDVNKRLEETKQREEALRLLRKDME 1052
Score = 63.5 bits (153), Expect = 8e-07
Identities = 123/686 (17%), Positives = 275/686 (40%), Gaps = 44/686 (6%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++DK V+ N +A ++ L + E I RN L+
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 2258 QALEN--KVGDFEAAIATLNDELLNEKD---DKKCIVNDRNIVEADKQALENK--VADFE 2100
+E+ +V + E A L ++E + K+ +++ E +ALE + +
Sbjct: 820 AEMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKA 879
Query: 2099 ATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA---IATLNDELL-NEKDDKKCI 1932
+ +N E+ + + + + +K++L+ + + + + ELL N+ D KC+
Sbjct: 880 EELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCL 939
Query: 1931 V---NDRNILEAAKQALEYKVADLEAAKTTL-------NDELERKKDDNNAIIKKALDKR 1782
++R LE + +E + DLE + + + +++R+K++ I + +
Sbjct: 940 FEMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDT 999
Query: 1781 ISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
S ++ R + LI + E + +L ++++ E++D
Sbjct: 1000 ESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENERED-- 1057
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE 1422
L K V GK T E+ + ++ + E+ + ER N + IR+ E
Sbjct: 1058 -LEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKME 1116
Query: 1421 LRKEKDGK--SALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR-KEKVDKSA 1251
K + G+ VE + E +E LE +NL+ M A + LR KE ++
Sbjct: 1117 AMKREMGEIEDMKVELTKQKENIDMKMEHARLEM--TNLEMMKA---DLLRQKEDIENQM 1171
Query: 1250 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
L E + E E +L + + + + +++++ K ++K+ +LE +
Sbjct: 1172 LAAKSERQQMEVMRTE--ILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 1070 LTDNQEGHEAEIERKLEASNLTHNDELH---KEKDDKESIMNDLDHVKAERQVLESKVSD 900
T + G ++R++E + + ++K++ E + ++ K + + +
Sbjct: 1230 -TKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQRAKDDMEFKRVETER 1288
Query: 899 METTYSTLNNELQQKMDDNEAFLNERD-----------------GLEAVKQGLEKRVLDL 771
+ + E+Q+ ++ E + ERD +EA ++ + K
Sbjct: 1289 QKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIINLIQQIEATREMVHKTKFQF 1348
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
E + +M T ++ N AE Q L I + E + L + ++ + + E+ L
Sbjct: 1349 ENRMAGSQMGTADQEEMN-AEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLL 1407
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLE 513
+ ++ + +E + E++++ +LE
Sbjct: 1408 KIEVQRRRREIEYREEKIMREQDELE 1433
Score = 61.2 bits (147), Expect = 4e-06
Identities = 115/678 (16%), Positives = 265/678 (39%), Gaps = 38/678 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++ + + + +E K ++ ++ D E + + +R LE +
Sbjct: 616 ENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKR 675
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLN 2079
+ ++ E L +E+L K+ E + + E + + E T +
Sbjct: 676 DLVSREIEQAEF----LRNEILRVKE------------EMESRWRETETEEVELRAKTQH 719
Query: 2078 D----ELLNEKDDKKCIVEADKQALESKVSV--FEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ E L E+ ++ + K ESK+ + ++ ++ L E+ ++DK ++ N
Sbjct: 720 ELERLEKLREETER-----SQKNIEESKIELMLWKESLDKLKGEM---EEDKHVVIMQMN 771
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQED 1737
+A ++ L + LE + + E+ K++ + I ++ ++L+ Q
Sbjct: 772 EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEI-----NRMRNELQR------QHA 820
Query: 1736 DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK-TALIKDLVAAEPGKR 1560
+M V E+ + EE +K + + T ++ +
Sbjct: 821 EMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAE 880
Query: 1559 TVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALV 1386
+ +I ++ + L++ +F +E ++LE + ++ +R E L+ + D L
Sbjct: 881 ELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLF 940
Query: 1385 E-NGEGCEAEKQGL----EKTVLERRASNLDTMDAIHEEELRKEK-----------VDKS 1254
E + E E E+ EK LE+R + D +++++K +D
Sbjct: 941 EMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTE 1000
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMA----------EKQALEK 1104
++ + E +++ E +++++ +N L+ R A E++ LEK
Sbjct: 1001 SMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDLEK 1060
Query: 1103 -RCSDLEAKNASLTDNQEGHE--AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA 933
R L K+ +E + AEIER + + +E K +KE ++ ++ +K
Sbjct: 1061 IRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKR 1120
Query: 932 ERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHD 753
E ++ DM+ + + KM+ E LE +K L ++ D+E +
Sbjct: 1121 EM----GEIEDMKVELTKQKENIDMKMEHARL---EMTNLEMMKADLLRQKEDIENQM-- 1171
Query: 752 IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+ + E + + K+ ++E + + + +K+ + + EL+E + K
Sbjct: 1172 --LAAKSERQQMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 572 ESKEKQDLEKRVLELTSK 519
+E ++E E+ K
Sbjct: 1230 TKREIGEMELMKREMEGK 1247
>ref|XP_011428631.1| PREDICTED: golgin subfamily B member 1-like isoform X4 [Crassostrea
gigas]
Length = 4864
Score = 121 bits (303), Expect = 3e-24
Identities = 134/642 (20%), Positives = 281/642 (43%), Gaps = 32/642 (4%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEA---AIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
NIL++ + L+N++ + T D L E DK+ +ND + DK+ +K+
Sbjct: 706 NILKSQLEDLDNQLRSLNSNSDVKDTKLDSLRKECKDKEKTINDLKLSVQDKETDTSKLQ 765
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLND----------ELL 1959
+ E+ + T L E +K+ I+++ +E A + L D +L+
Sbjct: 766 ESESALKTELCSLQTENKEKESIIQSLNVQIEELKHSLSAKDSELEDIHSQFSESHFKLI 825
Query: 1958 NEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA--LDK 1785
+ DK+ + N+ + ++ +L+ K + ELE KK++ + KK L++
Sbjct: 826 SITSDKESLSNELQQTNEKLDCVSNQLKELQEEKDCILKELEEKKENIKELSKKVKVLNE 885
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQ---KEK 1614
+SD + ++D E +N + S ++ + EELQ KEK
Sbjct: 886 NLSDKNNELERKDSE--LNHIKSDLNEVKTSLSELSSQKSAVDRQL----EELQTVCKEK 939
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAI 1434
D++ + ++E +++ E+V+ +SK +SL + E + L+ + + I KA
Sbjct: 940 DEQIQNLSS--SSEDSVKSLQELVAEKDSKIQSLLDTV--SECEVKLKEMENGVRISKAE 995
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVL------ERRASNLDTMDAIHEEELRK 1272
+E++ K + L E E E++ +E+T+L +R + L D H ++
Sbjct: 996 SDEKVHKSEQ---ELNEVRERLESKLSEVEETILVKDDEIKRVTNKLTETDCGHSSKVES 1052
Query: 1271 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1092
+ + L +N E +++ +E I SL ++L++ E+ +
Sbjct: 1053 LQSEIKTLLDNRSALSKELAAKKESFKKMEEQIVSLQNSLEKK-----------EETLQE 1101
Query: 1091 LEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLES 912
+ + N +L D + +++K++ + H + + + +++ E +L
Sbjct: 1102 MLSVNQTLKDENQKQAEFLQQKIQDLEVVHQERTELT-ESLGKLTREMEEKSTENSMLTE 1160
Query: 911 KVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGK 732
K+ + E L EL++K +NE LN+++ + + + + DL + +E+ K
Sbjct: 1161 KLHEKEQLLYDLKKELEKKQKENEDLLNDQESSDLLASKRKSTIEDLAERVSQLELSLEK 1220
Query: 731 DDDYNEAEKQTLKKRISELEEAISILTD---KAKKLLKDINIWLSEVTELQ----EDLNK 573
+ N K +++++ L++ + L+D K + ++ + S E Q E + +
Sbjct: 1221 EYSENSELKMSVEEKEMCLQQQNATLSDYKTKLDNIQQNSEMMQSAAKENQNEEPESIKQ 1280
Query: 572 ESKEKQDLEKRVLELTSKLEKCICGARDG-LSTIKEAWMSDC 450
E KEK++ ++ KLEK +C A+D L+ E S C
Sbjct: 1281 EMKEKEEKLIKLQNEVKKLEK-LCRAKDAKLAKQTEESKSQC 1321
Score = 81.6 bits (200), Expect = 3e-12
Identities = 135/648 (20%), Positives = 281/648 (43%), Gaps = 52/648 (8%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN 2118
S+ ++ N L + + + KV E LN+ ++ + + NI+ + ++ E+
Sbjct: 2987 SLESENNSLASELKHTKEKVNILEHDYVELNNSKSEAEELARTMEEKENILSSLIESKEH 3046
Query: 2117 KVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ L + + EKD+K + Q +E + + F TL +EL +EK+ K
Sbjct: 3047 EEG--------LMIKKMIEKDEKISSLLEKSQEMEERFNRFIQNNNTLANELKDEKEKVK 3098
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK--KALDKRISDLKA 1764
+ L +K + V +E + L+ + K+++ ++K K D++IS L
Sbjct: 3099 VLELKCIELRKSKTEADELVRSMEEKENILSSLVGSKENEEEIMLKKIKQKDEKISSLLE 3158
Query: 1763 DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE---LQKEKDDKTALI 1593
+ ++ E+ +N L+ +I+ NL+ L +E L+K++++K
Sbjct: 3159 NL--QEMEERLNQLV-----------QNEEILENLKETCLKHEQEIDLLKKQQEEKDLNF 3205
Query: 1592 KDLVAAEPGKRTVNEIVSHLE--SKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
+ +A T ++ L+ +KS+ E + + EV ++ A+ + I E +
Sbjct: 3206 RKAIA------TAKKLKFQLQQAAKSKEDLESEISTLKSEVEKKDANGVKDNDNIVETSV 3259
Query: 1418 RKEKD-GKSALVENGEGCEAEKQGLEKTV-----LERRASNLDTMDAIHEEELRKEKVDK 1257
+++ G L E E + Q LE+ ++ + T+ + EEE+ + D
Sbjct: 3260 KEQFPLGSEELRLKIESYEQQIQDLEEKCRSMQDFKQEIAEYKTLLSSREEEIAIMREDL 3319
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1077
+A+ EK + DLE I L + DR+ +E + S+++++
Sbjct: 3320 KLKENIASSIQAQLWEKEKCLNDLEAEIEILRTQYTTEKDRLTENILRIETQKSEMQSEI 3379
Query: 1076 ASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESK---V 906
+L + + E+ K E + T + +KE I+N++ K + +L +K
Sbjct: 3380 VTLEEQKLSLHNELAHKSEELD-TFMVNTKQNSQEKEKIINNM---KVQLDILMNKSQEE 3435
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERD----GLEAVKQGLEKRVLD-------LEATI 759
S ME T EL+ ++ E L E + L + Q L++ V + L+ T+
Sbjct: 3436 SAMEEVTQT-QKELETQLSKKEVSLKESEERNIELSNLLQSLQQEVRNKSELANTLQETL 3494
Query: 758 HDIEMKTGKDDDYNEA---EKQTLKKRISEL-------EEAISILTDKAKKL-------- 633
E++ G+ D+ N+ E L +++S + E+ +S +T+ AK+
Sbjct: 3495 KATEIEKGQLDELNQTIHKEIDVLNEKVSSMSNSLEQKEDLLSRVTNFAKQHYQRIMRSE 3554
Query: 632 -----LKDINIWLSEVTELQEDLNKESKEKQDLEKRV--LELTSKLEK 510
+++I + L + T+ + N ++++ ++LEK + LE +K EK
Sbjct: 3555 CVTEDIEEIFLELHKYTDQESTSNNQAQDMEELEKSLASLEKQNKEEK 3602
Score = 79.7 bits (195), Expect = 1e-11
Identities = 139/633 (21%), Positives = 261/633 (41%), Gaps = 62/633 (9%)
Frame = -2
Query: 2264 AKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIAT 2085
AKQ E+K + L ++ L + + +R+ + ++ Q ++ E I
Sbjct: 1311 AKQTEESK----SQCDSLLEEKTLTLEKTLNALQLERDGLVSEMQKIQKMYKGREIKIKK 1366
Query: 2084 LNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN-DELLNEKDDKKCIVNDRNILE 1908
L +EL++E++ EA+ L+ V+ + +E +KD ++ ++ N +E
Sbjct: 1367 L-EELISEQERHLSEYEAESIILKESVNELNEKVEDARYEEQCAQKDLQRMMIEQENTME 1425
Query: 1907 AAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK--KALDKRISDLKADAPQRDQEDD 1734
+ +Q L+ + + T L +++ K+D I+ + L+ + +DL ++D+E
Sbjct: 1426 SVEQ-LQQSIENTNKENTALKQQIQELKEDYQISIESVRILENKNTDLDLITKKKDEE-- 1482
Query: 1733 MNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTV 1554
+ L +L + E+ QK + K L GK
Sbjct: 1483 ---------------------IHRLTAQLLGVEEDQQKTVSES----KKLSLVTKGK--- 1514
Query: 1553 NEIVSHLESKSRSLKEHFLREEED-EVLE---RSASNLAIMKAIREEE-----LRKEKDG 1401
++K + L+E R++E+ EVL R AS L + +EE LR +K G
Sbjct: 1515 -------DAKVKKLEEMLKRKDEELEVLNIQLREASRLYESEIKKEESKSQEILRLQKLG 1567
Query: 1400 KSA---------LVENGEGCEAEKQGLEKTVLERRASNLDT-MDAIHEEE--LRKEKVDK 1257
K +V E AEK+ + +L+ + S + ++A+ EE LRKE D
Sbjct: 1568 KGKEAKAKKFEDVVSLQEKLLAEKE-TDSVILQGKISEMSIKINALESEEVHLRKELEDS 1626
Query: 1256 -SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQR----------DLDRVMAEKQAL 1110
+ E C+ EK LDL I N+ +++ + + ++ EK+ L
Sbjct: 1627 FKEIEELKHTCKDF----EKRELDLNQNIQKKNEEIEKLNADFKTSKENFNSLLLEKRDL 1682
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEIERKL---EASNLTHNDELHKEKDDKESIMNDLDHV 939
EK+ D++ ++ ERKL E + N+EL K K DK++I + + +
Sbjct: 1683 EKQIVDVQ-----------NIMSQTERKLCTVEQEVVRLNEELEKVKKDKDAISFEREKM 1731
Query: 938 KAERQVLESKVSDMETTYSTLNNELQQKMDD-----------NEAFLNERDGLEAVKQGL 792
K + +SK++ + N L +K D +E + + +E +K L
Sbjct: 1732 KMIEKGKKSKLNKFQEVVEKQENILTEKETDLLMMKERINDLSERLSQKEEEIEILKSDL 1791
Query: 791 ------EKRVLDLEATIHDIEMK-TGKDDDY------NEAEKQTLKKRISELEEAISILT 651
E+ E TI DI+ K DY NE + +L+++ + LE + L
Sbjct: 1792 DRSCQFEELCKQHELTISDIQQDFEEKSKDYLEDCMNNERKISSLEEKCAALENTVEFLQ 1851
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 552
+ K + DI + +E N+ K +++
Sbjct: 1852 RQEKDMELDIQSLSASASETDYWRNRCQKLEEN 1884
Score = 77.0 bits (188), Expect = 7e-11
Identities = 144/686 (20%), Positives = 264/686 (38%), Gaps = 47/686 (6%)
Frame = -2
Query: 2384 QALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQALENKVGDFEAAIATLN 2205
Q + ++A+++T +++ K N + ++A E + D EA I L
Sbjct: 3292 QDFKQEIAEYKTLLSSREEEIAIMREDLKLKENIASSIQAQLWEKEKCLNDLEAEIEILR 3351
Query: 2204 DELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADK 2025
+ EKD + + +E K +++++ E +L++EL ++ ++ + K
Sbjct: 3352 TQYTTEKDR---LTENILRIETQKSEMQSEIVTLEEQKLSLHNELAHKSEELDTFMVNTK 3408
Query: 2024 QALESKVSVFEAAIATLNDELLNEKDDKKCIVN-----------------------DRNI 1914
Q + K + L D L+N+ ++ + +RNI
Sbjct: 3409 QNSQEKEKIINNMKVQL-DILMNKSQEESAMEEVTQTQKELETQLSKKEVSLKESEERNI 3467
Query: 1913 -LEAAKQALEYKVADLEAAKTTLNDELERKK------DDNNAIIKKALD---KRISDLKA 1764
L Q+L+ +V + TL + L+ + D+ N I K +D +++S +
Sbjct: 3468 ELSNLLQSLQQEVRNKSELANTLQETLKATEIEKGQLDELNQTIHKEIDVLNEKVSSMSN 3527
Query: 1763 DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK------DDKT 1602
Q+ ED ++ + + ++E L LH+ +E D
Sbjct: 3528 SLEQK--EDLLSRVTNFAKQHYQRIMRSECVTEDIEEIFLELHKYTDQESTSNNQAQDME 3585
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE 1422
L K L + E + E V +LE +L E E+ L S AI I++
Sbjct: 3586 ELEKSLASLEKQNKEEKEKVQNLEQSYNALLE------ENSTLTEQLS--AIKNDIQQGA 3637
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT-MDAIHEEELRKEKVDKSALT 1245
+ KE LVE E+ L + NL T + + EE ++ T
Sbjct: 3638 VHKES--WDDLVEQLTIANDERNDLTMQI-----QNLTTEQNKVVEENNSLRDINHKLST 3690
Query: 1244 ENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1065
EN E K K + +LE + N LQ M++K L E+ A++T
Sbjct: 3691 ENRTQLEQLKDLTSKNI-ELESKLSEANRYLQE-----MSQKVNLN------ESSMANMT 3738
Query: 1064 DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTY 885
+ AE + KL+ N N ++ + DKE + + +E Q L SK+S+
Sbjct: 3739 LSIASLSAEND-KLKEENTRLNSLSNEFEKDKEEYEKKHNAIVSENQFLLSKISNFTADS 3797
Query: 884 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEK 705
+ + K + E +K+ R K+G D+ + E
Sbjct: 3798 DNMAKQEIFKATETPKLTTNFTDTEVLKESEHLR-------------KSGLDNINTQEEL 3844
Query: 704 QTLKKRISELEEA-------ISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 546
+T K+R+ +EEA + + K +K+L + + ++ +LQE++N
Sbjct: 3845 ETAKERLKIMEEAQEKTNEKLKLSETKCEKMLVKLKAFKTKCDKLQEEVNS--------L 3896
Query: 545 KRVLELTSKLEKCICGARDGLSTIKE 468
K+V E T +K A D LS ++E
Sbjct: 3897 KKVTEETGNSQK--THAEDYLSRVQE 3920
Score = 74.7 bits (182), Expect = 4e-10
Identities = 148/713 (20%), Positives = 285/713 (39%), Gaps = 71/713 (9%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAGKQALENKVADFETA---IATXXXXXXXXXXXXKSIVNDRNIL 2271
EKD ++Y N + + Q L +K+++F +A + D +L
Sbjct: 3766 EKDKEEYE-KKHNAIVSENQFLLSKISNFTADSDNMAKQEIFKATETPKLTTNFTDTEVL 3824
Query: 2270 EAA----KQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
+ + K L+N E A +++ E +K N++ ++ + E +
Sbjct: 3825 KESEHLRKSGLDNINTQEELETAKERLKIMEEAQEK---TNEK--LKLSETKCEKMLVKL 3879
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+A T D+L E + K + E + ++ + + + L + + +EKD+
Sbjct: 3880 KA-FKTKCDKLQEEVNSLKKVTEETGNSQKTHAEDYLSRVQEL-EVMCSEKDESN----- 3932
Query: 1922 RNILEAAKQALEYKVADLEAAKT---TLNDELERK-KDDNNAIIKKALDKRISDLKADAP 1755
N+L + L+ K+++LE+AK ++ +EL+ K K + + K + + DLK +
Sbjct: 3933 -NVLSCEIKELKTKLSELESAKEVQHSIEEELKGKLKALQDELNKSFQELQERDLKLSST 3991
Query: 1754 QRDQ---EDDMNALIXXXXXXXXXXXXXXKIVSNL--------EVNILI-----LHEELQ 1623
Q D ++++++L VS L E+ L+ HEE +
Sbjct: 3992 QEDITHFKNEISSLENFAENHKQKEMELLDRVSELQSKLNDTEELKPLLETTERKHEESE 4051
Query: 1622 KEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIM 1443
++ +D L L E ++ +I++ L+ L++ EE ++ ++ M
Sbjct: 4052 RKLEDSLMLCDSL---EVENKSYKDIIAKLKENISKLEQERRNAEEKQLERKTLLEKIEM 4108
Query: 1442 KAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKV 1263
+++++E DG E+ +AEK L K E S LD D+ E KEK+
Sbjct: 4109 LESERDQMQEEIDGYR---EDFNVLKAEKNEL-KNKCESIQSKLD--DSSDENNKLKEKI 4162
Query: 1262 DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEA 1083
AL E E+ ++ E+ DL+ +N + R+ D +E + +
Sbjct: 4163 --GALEWKVEEIESLEEELEEVRSDLDKKKLEINHII-RERDNFQSELEQI--------L 4211
Query: 1082 KNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
+ ++ E + E+E K+ N +EL K +I N++DH+K E + KVS
Sbjct: 4212 NTGNKGEDIESIKLELE-KVSERNEKLGEELESSTKQKIAITNEVDHLKEELKEAAEKVS 4270
Query: 902 ----------------------------------------DMETTYSTLNNELQQKMDDN 843
++E + EL + + +N
Sbjct: 4271 MFEVLQQENVKLKAEFDRETNNGFKETKTVFNESAAEKIKELEEELELIREELNETVSEN 4330
Query: 842 EAFLNERDGLEAVKQGLEKRVLDLEATIHDIE-MKTGKDDDYNEAEKQTLKKRISELEEA 666
E ++ E +K D EA ++E +K D N TLK++++E E
Sbjct: 4331 ETLRSKTQVSEYKALLFDKLQSDYEALKSEMESLKGNVARDTNAESFDTLKEKLNERESE 4390
Query: 665 ISILTDKAKKLLKDINIWLSEVTELQ---EDLNKESKEKQDLEKRVLELTSKL 516
+ L K + + ++ +V ++ DL KE +KQD +LE S+L
Sbjct: 4391 VQQLKSKMSTMNIESSVKKEDVMHVRSTPSDLEKELNDKQDQIDSILEELSEL 4443
Score = 68.2 bits (165), Expect = 3e-08
Identities = 127/655 (19%), Positives = 290/655 (44%), Gaps = 26/655 (3%)
Frame = -2
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDR-NIVEADKQALENKVADFEATIATLND 2076
L+ K+ + + IA ++L K ++ + ++ ++A++ + E A L
Sbjct: 96 LKRKLEEKDRIIADKEEQLAT----KNALIEAKVKVISEQEEAVKTLSSQLEGN-ANLIA 150
Query: 2075 ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQ 1896
+L E+ + E+ Q + +++ + I LN+++L D +K +++ + + +
Sbjct: 151 QLQTEQKTESSTPESGVQEMYAQIVYKDNKIMELNNKIL---DHEKKMMDLQEFISEKNE 207
Query: 1895 ALEYKVADLEAAKTTLNDELERKKDDN---NAIIKKALDKRISDLKAD-APQRDQEDDMN 1728
++ + E +TT+ R+KD N A++ L ++ + + + A ++Q + N
Sbjct: 208 VIKGRDKVFEILQTTI-----REKDQNIQGQAMLISKLSAKVENYEEEIAEMKEQVEKAN 262
Query: 1727 ------------ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
L +V++L N+ + +EL ++D +++L
Sbjct: 263 HALKLESEKFDMKLRETQKYFEESLQESQGLVASLRENVKVKDDELLLREND----LREL 318
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
++ ++ + I++ E L++H L+ E ++ + + +K I E L+KE
Sbjct: 319 ISKH--EKDIQRIMAKGEV---DLQDHVLKMLEQKLKDTNEVLEGKIKVI--EVLQKEVT 371
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA-IHEEELR----KEKVDKSALTEN 1239
K +E EG +K EK L+ + L M A I + E++ K+K+D + + +
Sbjct: 372 AKDREIE--EGLHVQKNFKEK--LQTTSEQLMLMQANIVDMEIQWKDEKKKLD-AKIRDL 426
Query: 1238 GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
E E E+ E TV ++ + A + + + + ++ A A+
Sbjct: 427 IEKQELERTEKELTVQTMQGQLYQYQTAYTQAVTQYNSLQERFHHSTRPGGAVPAAQVQP 486
Query: 1058 QEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSD----MET 891
E + + +++A+ D L ++ +KE I+ +L+H K++ + ++ D M++
Sbjct: 487 VEETKLQAPEQMDATAQVMAD-LKEKLLEKEKIIKELEHFKSDFEAAHVQLEDLQKKMDS 545
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA 711
L L+ D + L ++ L A + LEK +L+ ++ E K +D
Sbjct: 546 KVEELKKNLKAAEDTSAKNLKQKAQLTAKIKTLEKENGELKVSLSTAENKHRED------ 599
Query: 710 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 531
+L+++ ++ EE + ++ + L K+++ ++ ++LQE LNK +++++E+ +
Sbjct: 600 -IASLQEQQTKAEELLQKSSNDSGSLEKEVSTVTADNSKLQE-LNK--NQEKEIEELKVT 655
Query: 530 LTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKT 366
L SK E + + D +KE M+ + +L Q S ++I K+
Sbjct: 656 LQSKEESLVSMSSDLEGKVKEIQSLQQMLHQHETEMTELKQLKQESDSEVNILKS 710
Score = 66.2 bits (160), Expect = 1e-07
Identities = 173/868 (19%), Positives = 342/868 (39%), Gaps = 160/868 (18%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
K D V + L + K A++ ++ + +T + V L A K
Sbjct: 905 KSDLNEVKTSLSELSSQKSAVDRQLEELQTVCKEKDEQIQNLSSSSEDSVKSLQELVAEK 964
Query: 2258 ----QALENKVGDFEAAIATLND--ELLNEKDDKKCIVNDRNIVEADKQALENKVADFEA 2097
Q+L + V + E + + + + + D+K +++ + E ++ LE+K+++ E
Sbjct: 965 DSKIQSLLDTVSECEVKLKEMENGVRISKAESDEKVHKSEQELNEV-RERLESKLSEVEE 1023
Query: 2096 TIATLNDEL---LNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKC--- 1935
TI +DE+ N+ + C + ++L+S++ + L+ EL +K+ K
Sbjct: 1024 TILVKDDEIKRVTNKLTETDCGHSSKVESLQSEIKTLLDNRSALSKELAAKKESFKKMEE 1083
Query: 1934 -IVNDRNILEAAKQALE---------------------YKVADLEAA---KTTLND---- 1842
IV+ +N LE ++ L+ K+ DLE +T L +
Sbjct: 1084 QIVSLQNSLEKKEETLQEMLSVNQTLKDENQKQAEFLQQKIQDLEVVHQERTELTESLGK 1143
Query: 1841 ---ELERKKDDNNAIIKKALDKR--ISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXX 1677
E+E K +N+ + +K +K + DLK + ++ +E++ L+
Sbjct: 1144 LTREMEEKSTENSMLTEKLHEKEQLLYDLKKELEKKQKENE--DLLNDQESSDLLASKRK 1201
Query: 1676 KIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL----- 1512
+ +L + L L+KE + + L + E + N +S ++K ++
Sbjct: 1202 STIEDLAERVSQLELSLEKEYSENSELKMSVEEKEMCLQQQNATLSDYKTKLDNIQQNSE 1261
Query: 1511 ------KEHFLREEED---EVLERSASNLAIMKAIRE-EELRKEKDGKSA--LVENGEGC 1368
KE+ E E E+ E+ + + +++ E+L + KD K A E+ C
Sbjct: 1262 MMQSAAKENQNEEPESIKQEMKEKEEKLIKLQNEVKKLEKLCRAKDAKLAKQTEESKSQC 1321
Query: 1367 ----EAEKQGLEKTV----LERRA--SNLDTMDAIHE-EELRKEKVDKSALTENGEGCEA 1221
E + LEKT+ LER S + + +++ E++ +K+++ + E
Sbjct: 1322 DSLLEEKTLTLEKTLNALQLERDGLVSEMQKIQKMYKGREIKIKKLEELISEQERHLSEY 1381
Query: 1220 EKQGPEKTVLDLEPTIPSLNDAL----------QRDLDRVMAEK-----------QALEK 1104
E + + L+ ++ LN+ + Q+DL R+M E+ Q++E
Sbjct: 1382 EAES-----IILKESVNELNEKVEDARYEEQCAQKDLQRMMIEQENTMESVEQLQQSIEN 1436
Query: 1103 RCSDLEAKNASLTDNQEGHEAEIE--RKLEASNLTHNDELHKEKDDKE--------SIMN 954
+ A + + +E ++ IE R LE N T D + K+KD++ +
Sbjct: 1437 TNKENTALKQQIQELKEDYQISIESVRILENKN-TDLDLITKKKDEEIHRLTAQLLGVEE 1495
Query: 953 DLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAF-LNERDGLEAVKQGLEKR-- 783
D +E + L + L L++K ++ E + R+ + ++K
Sbjct: 1496 DQQKTVSESKKLSLVTKGKDAKVKKLEEMLKRKDEELEVLNIQLREASRLYESEIKKEES 1555
Query: 782 ----VLDLEATIHDIEMKTGKDDDYNE------AEKQT----LKKRISELEEAISILTDK 645
+L L+ E K K +D AEK+T L+ +ISE+ I+ L +
Sbjct: 1556 KSQEILRLQKLGKGKEAKAKKFEDVVSLQEKLLAEKETDSVILQGKISEMSIKINALESE 1615
Query: 644 AKKLLKDINIWLSEVTELQE----------DLN-----------------KESKE----- 561
L K++ E+ EL+ DLN K SKE
Sbjct: 1616 EVHLRKELEDSFKEIEELKHTCKDFEKRELDLNQNIQKKNEEIEKLNADFKTSKENFNSL 1675
Query: 560 ---KQDLEKRVLE---LTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFS 399
K+DLEK++++ + S+ E+ +C + + E + + + FE
Sbjct: 1676 LLEKRDLEKQIVDVQNIMSQTERKLCTVEQEVVRLNEE-LEKVKKDKDAISFEREKMKMI 1734
Query: 398 RKTSPLDITKTCDAVDISEDSTTNIQVD 315
K + K + V+ E+ T + D
Sbjct: 1735 EKGKKSKLNKFQEVVEKQENILTEKETD 1762
Score = 66.2 bits (160), Expect = 1e-07
Identities = 118/612 (19%), Positives = 253/612 (41%), Gaps = 30/612 (4%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADK----QALENKVAD 2106
LE + + ++ + E A+ LND LL E + K ++ + Q+LEN+ +
Sbjct: 2522 LEEKSKTILSQKNNEETALKELNDSLLEEIEQLKQVIESSKGERIESLSRVQSLENENSR 2581
Query: 2105 FEATIATLNDELLNEK----DDKKCIVEADKQALESKVSVFEAAIATLN-DELLNEKD-- 1947
I +ELL E+ + + IV + + E V A+ N L EK+
Sbjct: 2582 LNEEIVRKKEELLQERTANTELENTIVMLNSKFEEQNQHVIALEKASFNISASLQEKNCQ 2641
Query: 1946 ----DKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRI 1779
I + I + ++A+EY+ L + T E+E++ +KK+L +
Sbjct: 2642 IETLTSNYIQSQDLIKQHQQKAIEYE--QLLSKSETNVKEMEKETTS----LKKSLRQGH 2695
Query: 1778 SDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTA 1599
+L + D E + L+ K +E + +EL+KE + T
Sbjct: 2696 EELSR--MKEDFEKEKRQLLAHLDEKENQLIHLQKSNDFMEREM----QELKKESHNITN 2749
Query: 1598 LIKDLVAAEPGKRTVN-----EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAI 1434
++ + + + +R + ++ ++S++ E +++ E+E+ + S + +
Sbjct: 2750 VVNEPIIQKHQERLLGAAPSTSVMEMETTESKNDAEGTIQKLEEEIAQLELSKRELTSQV 2809
Query: 1433 RE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEE----LRK 1272
++ ++L + +++ E ++ +G E+ + E ++ N+ ++ E L
Sbjct: 2810 QQLTQDLYQTHQNQNSDSNKAEMLVSKLRGTEERLEEMKSQNIQLQKSVSEMNESISLAN 2869
Query: 1271 EKVDK--SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 1098
KV + + +NG E + + E +A+ +++V KQ+ E+
Sbjct: 2870 SKVREYEELVKKNGNIIEELTLQKDSLIKSYEEEKEISKNAIADYMNQVHHVKQSEEELK 2929
Query: 1097 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL 918
++ E + + E + E+ E L N+ E + DLD+++ + L
Sbjct: 2930 ANSEQSRLRIVE-LESNCCEVNAAFENLKLQSNESASSLSSQIEKLTKDLDNLQQVVRSL 2988
Query: 917 ESKVSDMETTYSTLNNELQQKMDDNEAFLN--ERDGLEAVKQGLEKRVLDLEATIHDIEM 744
ES+ NN L ++ + +N E D +E E +L T+ + E
Sbjct: 2989 ESE-----------NNSLASELKHTKEKVNILEHDYVELNNSKSEAE--ELARTMEEKEN 3035
Query: 743 KTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 564
+ E E+ + K++ E +E IS L +K++++ + N ++ L +L E +
Sbjct: 3036 ILSSLIESKEHEEGLMIKKMIEKDEKISSLLEKSQEMEERFNRFIQNNNTLANELKDEKE 3095
Query: 563 EKQDLEKRVLEL 528
+ + LE + +EL
Sbjct: 3096 KVKVLELKCIEL 3107
>ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeba histolytica
HM-1:IMSS] gi|56470397|gb|EAL48061.1| Viral A-type
inclusion protein repeat, putative [Entamoeba histolytica
HM-1:IMSS]
Length = 1813
Score = 120 bits (302), Expect = 4e-24
Identities = 123/601 (20%), Positives = 272/601 (45%), Gaps = 25/601 (4%)
Frame = -2
Query: 2276 ILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEA 2097
ILE K+ L +K+ + ++ LN+EL K++K+ I N+ + +K+++ N++ +
Sbjct: 223 ILENEKKDLIDKMANENDGMSKLNEELTQIKNEKESINNELIQTKQEKESINNELTQLKT 282
Query: 2096 TIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDR- 1920
+EL + +K ++E + E + +L EK++K+ + ++
Sbjct: 283 DNDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNEL-----SQLKQEKEEKENELKEQV 337
Query: 1919 NILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE 1740
+E K L ++++ + LN+EL + K + K+ ++ ++ +K + + ++E
Sbjct: 338 KKMEEEKSKLITELSNGSDGISKLNEELTQTKQE-----KEEINNELNSIKEEKKRIEEE 392
Query: 1739 DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKR 1560
+ I N E+ EE +K +++K L+K++ + G
Sbjct: 393 KNQ------------------IINENKEIK-----EEKEKIEEEKKELLKEIEKEKEGNN 429
Query: 1559 TV-NEI------VSHLESKSRSL-----KEHFLREEEDEVLERSASNLAIMKAIREEELR 1416
+ NEI + +E K++ + KE +EE E L++ + + K E E
Sbjct: 430 QLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKN 489
Query: 1415 KEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNL--DTMDAIHEEELRKEKVDKSAL 1248
+ D K+ + EK+ + EKT +E + + + E+E K+++D
Sbjct: 490 ELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKA 549
Query: 1247 TENGEGCEAEKQGPEKTVLDLE-PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
+ + E K EK L + T+ + +Q++L+++ EK E+ + ++ +
Sbjct: 550 DNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQ 609
Query: 1070 LTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMET 891
+ D + +I + N+ + K KD+KE+I N+L+ +K ER + ++ + +
Sbjct: 610 VEDEKAKLITDIANGNDGLTKL-NEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKE 668
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL--EKRVLDLEATIHDIEMKTGKDDDYN 717
NE Q ++ LNE + ++ KQ + EK V+ E ++ K N
Sbjct: 669 EIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIEN 728
Query: 716 E-----AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 552
E EKQ ++ +++ ++ + D+ KL+ +++ +++L E+L + +EK++
Sbjct: 729 ELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKEN 788
Query: 551 L 549
+
Sbjct: 789 V 789
Score = 113 bits (283), Expect = 7e-22
Identities = 148/687 (21%), Positives = 291/687 (42%), Gaps = 44/687 (6%)
Frame = -2
Query: 2438 KDDKKYVVNDRN-ILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAA 2262
K++KK + ++N I+ K+ E + E SI + LE +
Sbjct: 990 KEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTT-------SIEELKGRLEES 1042
Query: 2261 KQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL 2082
K + + I+ LND L + KK + N + +++ E + I +L
Sbjct: 1043 KGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEM---INSL 1099
Query: 2081 NDEL--LNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEK-------DDKKCIV 1929
N+++ LNEK+ + + AL++++S + + +L+ + ++K C+
Sbjct: 1100 NNQITQLNEKEKQ---MNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVE 1156
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1749
+RN + EYK T+N+ELE+ K + N + K D I +L +
Sbjct: 1157 QERNKINE-----EYK---------TVNEELEKNKKELNDLQTK-YDNEILELNKN---- 1197
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 1569
+D++N+LI +NL+ L E+++K +++K+ LI +L
Sbjct: 1198 --KDELNSLI-----------------NNLKEEKTNLEEQVKKMEEEKSKLITELSNGSD 1238
Query: 1568 GKRTVNEIVSHLESKSRSLKEHF--LREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 1395
G +NE ++ + + + ++EE+ + E + K I+EE+ + E++ K
Sbjct: 1239 GVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKE 1298
Query: 1394 ALVENGEGCEAEKQGLEKTVLERRASNLDT----MDAIHEEELRKEKVDKSALTENGEGC 1227
L E E EK+G + L+ + + T ++ ++E + + + E E
Sbjct: 1299 LLKE----IEKEKEGNNQ--LQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENL 1352
Query: 1226 EAE----KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+ E K+ K + DL L+ L +++ + EK+ + K L+ +N + D
Sbjct: 1353 QKELNQIKEEKSKLITDLSNGNDGLSK-LNEEIETINKEKEGIRKELESLKEENNKIQDE 1411
Query: 1058 QEGHEAEIER-KLEASNLTH-----NDELHKEKDDKESIMNDLDHVKAERQVLESKVSDM 897
E E+ + K E L H ND +++ +D I ND + + + L+++++ +
Sbjct: 1412 LEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKL 1471
Query: 896 ETTYSTLNNEL-------QQKMDDNEAFLNERDGL--EAVKQGLEKRVLDLEATIHDIEM 744
++ L+N L +Q ++ A ERD L + K EKR ++ E + E+
Sbjct: 1472 KSENEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEV 1531
Query: 743 KTGKDDDYNEAE---------KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
NE E KQ LK+ S++EE K +++ E+TE
Sbjct: 1532 NEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEKESNEIKKKEELQELQEEITEK 1591
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLEK 510
D+ +E + +EK + E +E+
Sbjct: 1592 DNDIKNLKEEIERIEKELQEKEEDMEQ 1618
Score = 111 bits (278), Expect = 3e-21
Identities = 136/635 (21%), Positives = 274/635 (43%), Gaps = 77/635 (12%)
Frame = -2
Query: 2141 ADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESK----------VSVFE 1992
A + E A I N L NE ++ K +A L++K V + E
Sbjct: 166 ASETTAEEVNRSVNAQIEEENKRLQNENEELKKKCDAQDSLLKTKMKSEMEAKKKVEILE 225
Query: 1991 AAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDN- 1815
L D++ NE D + + ++ K+++ ++ + K ++N+EL + K DN
Sbjct: 226 NEKKDLIDKMANENDGMSKLNEELTQIKNEKESINNELIQTKQEKESINNELTQLKTDND 285
Query: 1814 ---NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNIL 1644
N + + +K K + + + E MN L ++ E
Sbjct: 286 QKENELNQVRHEKDEVIEKFNTSKEENEKIMNEL--------------SQLKQEKEEKEN 331
Query: 1643 ILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--LREEEDEVLE 1470
L E+++K +++K+ LI +L G +NE ++ + + + ++EE+ + E
Sbjct: 332 ELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNELNSIKEEKKRIEE 391
Query: 1469 RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT-MDAI 1293
+ K I+EE+ + E++ K L E E EK+G L+ + + T M I
Sbjct: 392 EKNQIINENKEIKEEKEKIEEEKKELLKE----IEKEKEG--NNQLQNEINTIQTRMKEI 445
Query: 1292 HE----------EELRKEKVDKSALTENGEGCEAEKQGPE---KTVLDLEPTIPSLNDAL 1152
E +E+ K K ++ L + + EKQ E ++D++ + + L
Sbjct: 446 EEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKENELNKL 505
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 972
+ + +++ EK +E + + + LT+ +E + E++ ++A N T E++K ++
Sbjct: 506 KEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELD-SIKADNSTKELEINKINEE 564
Query: 971 KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL------QQKMDDNEAFL-----NE 825
K + ND D V+ E++ ++ +++ ++ S EL +Q+++D +A L N
Sbjct: 565 KNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANG 624
Query: 824 RDGLEAVKQGLEKRVLDLEATIHDI-EMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 648
DGL + + ++K + E +++ ++K +D+ NE K K+ I + E L +
Sbjct: 625 NDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNK--TKEEIKQKENETIQLNE 682
Query: 647 KAKKLLKDINIWL------------------SEVTELQED-------LNKESKEKQDLE- 546
+ LL ++N +E+T+L ED LN+ EKQ++E
Sbjct: 683 EKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIKTEKQEIEN 742
Query: 545 ---------KRVLELTSKLEKCICGARDGLSTIKE 468
+++ + SKL + DG+S + E
Sbjct: 743 ELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNE 777
Score = 106 bits (265), Expect = 9e-20
Identities = 145/651 (22%), Positives = 280/651 (43%), Gaps = 61/651 (9%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E K L ++ + I+ LN+EL K +K+ I + +E +K+ LE + +
Sbjct: 881 IEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEI---QKALEEEKEKLERIETELKE- 936
Query: 2093 IATLNDELLNEKDDKKCIVEAD--KQALESKVSVFEAAIAT------LNDELLNEKDDKK 1938
I EL EK+ K I E +Q L + E T +N+EL + K++KK
Sbjct: 937 IKEAKQELEEEKN--KTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKK 994
Query: 1937 CIVNDRN--------ILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKAL 1791
I ++N I E +++E K ++ + T++ + LE K + I +K
Sbjct: 995 RIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGERIEI-EKER 1053
Query: 1790 DKRISDL-----KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSN-----------L 1659
D+ IS+L + + ++ E+ N + ++N +
Sbjct: 1054 DRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQM 1113
Query: 1658 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1479
++ L +L + + + KDL+ ++ +NE +E + + E + E+
Sbjct: 1114 NEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEE- 1172
Query: 1478 VLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTV--LERRASN 1314
LE++ L ++ + E L K KD ++L+ N + EK LE+ V +E S
Sbjct: 1173 -LEKNKKELNDLQTKYDNEILELNKNKDELNSLINN---LKEEKTNLEEQVKKMEEEKSK 1228
Query: 1313 LDT-----MDAIHE--EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 1155
L T D + + EEL + K +K + + EK K + + + I + N
Sbjct: 1229 LITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEK----KRIEEEKNQIINENKE 1284
Query: 1154 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA---EIERKLEASNLTHNDELHK 984
++ + +++ EK+ L K + N L + + EIE K + +N E+ K
Sbjct: 1285 IKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAK 1344
Query: 983 EKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE------- 825
K+++E++ +L+ +K E+ L + +S+ S LN E++ + E E
Sbjct: 1345 FKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEE 1404
Query: 824 ----RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 657
+D LE Q L K + E IHD+ T +D N+ L + +++++
Sbjct: 1405 NNKIQDELEQKNQELSKVKEEKEKLIHDL---TNGNDGINQ-----LNEDLNQIKNDKEE 1456
Query: 656 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCI 504
LT+K +L +IN SE EL +L+ E + + + + V + + ++ +
Sbjct: 1457 LTEKNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEERDELV 1507
Score = 106 bits (264), Expect = 1e-19
Identities = 144/672 (21%), Positives = 294/672 (43%), Gaps = 68/672 (10%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEAAIATLNDEL--LNE-----KDDKKCIVNDRNIVEADKQALE 2121
N ++ KQ +E++ IA ND L LNE KD+K+ I N+ N ++ ++ +
Sbjct: 601 NKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNIS 660
Query: 2120 NKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNE---- 1953
N+ + I +E + ++K ++ Q E K + E A + E NE
Sbjct: 661 NEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKI-EDEKAVIQQEKENEITKL 719
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE----LERKKDDNNAIIKKALDK 1785
+DK I N+ N ++ KQ +E ++ + K + DE + + N+ I K L++
Sbjct: 720 NEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISK--LNE 777
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
++ K +++E+ +N L + + L+ + +EL+++ ++
Sbjct: 778 ELTQTK-----QEKENVLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEV 832
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFL-----REEEDEVLERSASNLAIMK 1440
+ L E K ++ +S+ + + K+ + +EE++ L+ + K
Sbjct: 833 SKL-------EEEKGNISNELSNTKQELEQKKQEIITITQEKEEKENELKEQVKKIEEEK 885
Query: 1439 AIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD 1260
+ EL DG S L E + EK+ ++K LE L+ + E EL++ K
Sbjct: 886 SKLITELSNGSDGISKLNEELTQTKQEKEEIQK-ALEEEKEKLERI----ETELKEIKEA 940
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSL------NDALQRDLDRVMAEKQALEKRC 1098
K L E EK ++ + + + + L + + +L+ + EK+ +E
Sbjct: 941 KQELEEEKNKTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIE--- 997
Query: 1097 SDLEAKNASLTDNQEGHEAEI----ERKLEASNLT---------------HNDELHKEKD 975
E KN + +N+E E I E+ E ++LT E+ KE+D
Sbjct: 998 ---EEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGERIEIEKERD 1054
Query: 974 DKESIMNDL----DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER----- 822
S +ND+ + +K + + +++++M+ ++ NE+ +++ LNE+
Sbjct: 1055 RVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMN 1114
Query: 821 DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKA 642
+ + A++ L + ++LE D+ K NE EK +++ +++ E + ++
Sbjct: 1115 EQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINE-EKDCVEQERNKINEEYKTVNEEL 1173
Query: 641 KKLLKDIN----IWLSEVTELQED-------LNKESKEKQDLE---KRVLELTSKLEKCI 504
+K K++N + +E+ EL ++ +N +EK +LE K++ E SKL +
Sbjct: 1174 EKNKKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITEL 1233
Query: 503 CGARDGLSTIKE 468
DG+S + E
Sbjct: 1234 SNGSDGVSKLNE 1245
Score = 105 bits (263), Expect = 1e-19
Identities = 130/616 (21%), Positives = 275/616 (44%), Gaps = 29/616 (4%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
LE K+ L + ++ I LN KD+ ++N+ ++ +K LE +V E
Sbjct: 1173 LEKNKKELNDLQTKYDNEILELN----KNKDELNSLINN---LKEEKTNLEEQVKKMEEE 1225
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ L EL N D + E Q + K + N+EL + K++KK I ++N
Sbjct: 1226 KSKLITELSNGSDGVSKLNEELTQTKQEKEEI--------NNELNSIKEEKKRIEEEKNQ 1277
Query: 1913 LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDD 1734
+ + ++ + +E K L E+E++K+ NN + + I + +++QE
Sbjct: 1278 IINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEI--NTIQTRMKEIEEKNQE-- 1333
Query: 1733 MNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTV 1554
K ++ + L +EL + K++K+ LI DL G +
Sbjct: 1334 -------------IICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKL 1380
Query: 1553 NEIVSHLESKSRSLKEHF--LREEEDEV---LERSASNLAIMKAIREE---ELRKEKDGK 1398
NE + + + +++ L+EE +++ LE+ L+ +K +E+ +L DG
Sbjct: 1381 NEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGI 1440
Query: 1397 SALVENGEGCEAEKQGL-EKTV--------LERRASNLDTMDAIHEEELRKEKVDKSALT 1245
+ L E+ + +K+ L EK V L+ L + +E L++ + +A+
Sbjct: 1441 NQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIK 1500
Query: 1244 ENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1065
E + + + E+ +E + + + ++ EK+ L + C++L+ L
Sbjct: 1501 EERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQ 1560
Query: 1064 DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTY 885
E EIE++ E++ + +EL + +++ ND+ ++K E + +E ++ + E
Sbjct: 1561 SKIE----EIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEEDM 1616
Query: 884 STLNN------ELQQKMDDNEAFL-NERDGLEAVKQGLEKR----VLDLEATIHDI-EMK 741
++N EL+ K+ + + L E+ E++ E+ +++L+ +++ +M
Sbjct: 1617 EQMSNNTEELEELKNKLTETQRLLEEEKKEKESISNEFEETKEQVLVELQRVNNEMNKMN 1676
Query: 740 TGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 561
K +D NE E EL+E I +K K ++ N L EV++L+ +L++ E
Sbjct: 1677 EIKQEDENEKE---------ELQEHI----NKLKSQIERENEQLKEVSKLKWELSELKTE 1723
Query: 560 KQDLEKRVLELTSKLE 513
+ +++ ++ S L+
Sbjct: 1724 NESMKQMIMNKKSLLD 1739
Score = 103 bits (257), Expect = 7e-19
Identities = 151/748 (20%), Positives = 314/748 (41%), Gaps = 92/748 (12%)
Frame = -2
Query: 2435 DDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQ 2256
+DK + N+ N ++ KQ +EN++ + +++ +E K
Sbjct: 721 EDKTVIENELNQIKTEKQEIENELNQTK---------------------DEKQKIEDEKS 759
Query: 2255 ALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLND 2076
L ++ + I+ LN+EL K +K+ ++N+ N ++N+ A F+ N
Sbjct: 760 KLITELSNGNDGISKLNEELTQTKQEKENVLNELN-------QIKNEFASFKEQ----NT 808
Query: 2075 ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDD----KKCIVNDRNILE 1908
+ NE D+ V+ + + ++VS E +++EL N K + K+ I+ E
Sbjct: 809 QKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQKKQEIITITQEKE 868
Query: 1907 AAKQALEYKVADLEAAKTTL--------------NDELERKKDDNNAIIK------KALD 1788
+ L+ +V +E K+ L N+EL + K + I K + L+
Sbjct: 869 EKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEEKEKLE 928
Query: 1787 KRISDLKA-DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD 1611
+ ++LK +++ E++ N I KIV EEL + K
Sbjct: 929 RIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIV-----------EELTQTKQ 977
Query: 1610 DKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI--MKA 1437
+K + +L + + K+ + E + + ++++ +KE ++ E++ E ++ +I +K
Sbjct: 978 EKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKG 1037
Query: 1436 IREE------ELRKEKD--------------GKSALVENGEGCEAEKQ----GLEKTVLE 1329
EE E+ KE+D G VE E Q G E ++
Sbjct: 1038 RLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMIN 1097
Query: 1328 RRASNLDTMDA--------------------IHEEELRKEKVDK----SALTENGEGCEA 1221
+ + ++ I+ EE++K+ ++ + + E + E
Sbjct: 1098 SLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQ 1157
Query: 1220 EKQGPE---KTVLD-LEPTIPSLNDALQRDLDRVMAE----KQALEKRCSDLEAKNASLT 1065
E+ KTV + LE LND LQ D + E K L ++L+ + +L
Sbjct: 1158 ERNKINEEYKTVNEELEKNKKELND-LQTKYDNEILELNKNKDELNSLINNLKEEKTNLE 1216
Query: 1064 DNQEGHEAEIERKL-EASNLTH-----NDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
+ + E E + + E SN + N+EL + K +KE I N+L+ +K E++ +E + +
Sbjct: 1217 EQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKN 1276
Query: 902 DMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 723
+ + E ++ ++ + L E + + L+ + ++ + +IE K +
Sbjct: 1277 QIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIIC 1336
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 543
N E K+ L++ ++ + ++ KL+ D++ +++L E++ +KEK+ + K
Sbjct: 1337 DNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRK 1396
Query: 542 RVLEL---TSKLEKCICGARDGLSTIKE 468
+ L +K++ + LS +KE
Sbjct: 1397 ELESLKEENNKIQDELEQKNQELSKVKE 1424
Score = 102 bits (254), Expect = 2e-18
Identities = 126/648 (19%), Positives = 291/648 (44%), Gaps = 61/648 (9%)
Frame = -2
Query: 2270 EAAKQALE---NKVGDFEAAIATLNDELLNEKDDKKCIVNDRNI-VEADKQALENKVADF 2103
E K+ +E N++ + + + +E++N +++ +N++ + AL+ +++
Sbjct: 1068 EGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLSQS 1127
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN- 1926
+ + +L+ E +K + +K +E + + T+N+EL K + +
Sbjct: 1128 NINLEEVKKDLI-ESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNKKELNDLQTK 1186
Query: 1925 -DRNILEAAKQALEYK--VADLEAAKTTLNDELERKKDDNNAIIKKALDKR--ISDLKAD 1761
D ILE K E + +L+ KT L +++++ +++ + +I + + +S L +
Sbjct: 1187 YDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEE 1246
Query: 1760 APQRDQEDDM--NALIXXXXXXXXXXXXXXKIVS-NLEVNILILHEELQKEKDDKTALIK 1590
Q QE + N L +I++ N E+ EE +K +++K L+K
Sbjct: 1247 LTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIK-----EEKEKIEEEKKELLK 1301
Query: 1589 DLVAAEPGKRTV-NEI------VSHLESKSRSL-----KEHFLREEEDEVLERSASNLAI 1446
++ + G + NEI + +E K++ + KE +EE E L++ + +
Sbjct: 1302 EIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKE 1361
Query: 1445 MKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE--EELRK 1272
K+ +L DG S L E E EK+G+ K + + N D + + +EL K
Sbjct: 1362 EKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSK 1421
Query: 1271 EKVDKSAL----TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 1104
K +K L T +G + + D E + N LQ +++++ +E + L
Sbjct: 1422 VKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEE-LTEKNVQLQNEINKLKSENEELSN 1480
Query: 1103 RCS----DLEAKNASLTDNQEGHEA-------------EIERKLEASNLTHNDELHKEKD 975
S L+ N + +E + ++E +L + N+++ + +
Sbjct: 1481 NLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQINN 1540
Query: 974 DKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG-LEAVKQ 798
+KE + + + +K + L+SK+ ++E + + ++++ + + + E+D ++ +K+
Sbjct: 1541 EKEQLNQECNELKQNLKELQSKIEEIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKE 1600
Query: 797 GLEKRVLDLEATIHDIEMKTGKDDDYNE-----AEKQTLKKRISELEEAISILTDKAKKL 633
+E+ +L+ D+E + ++ E E Q L + + +E+IS ++ K+
Sbjct: 1601 EIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESISNEFEETKEQ 1660
Query: 632 LKDINIWLSEVTELQEDLNKESK-------EKQDLEKRVLELTSKLEK 510
+ L E+ + ++NK ++ EK++L++ + +L S++E+
Sbjct: 1661 V------LVELQRVNNEMNKMNEIKQEDENEKEELQEHINKLKSQIER 1702
Score = 72.0 bits (175), Expect = 2e-09
Identities = 76/381 (19%), Positives = 162/381 (42%), Gaps = 36/381 (9%)
Frame = -2
Query: 1565 KRTVNEIVSHLESK---SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 1395
KR E H S+ + SL EE + + EEL+K+ D +
Sbjct: 145 KRNSTENTGHSSSEHSATSSLASETTAEEVNRSVNAQIEEENKRLQNENEELKKKCDAQD 204
Query: 1394 ALVENGEGCEAEK-------QGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 1236
+L++ E E + +K ++++ A+ D M ++EE L + K +K ++
Sbjct: 205 SLLKTKMKSEMEAKKKVEILENEKKDLIDKMANENDGMSKLNEE-LTQIKNEKESINNEL 263
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN- 1059
+ EK+ + L+ ND + +L++V EK + ++ + + +N + +
Sbjct: 264 IQTKQEKESINNELTQLKTD----NDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNEL 319
Query: 1058 ----QEGHEAEIERKLEASNLTH-------------------NDELHKEKDDKESIMNDL 948
QE E E E K + + N+EL + K +KE I N+L
Sbjct: 320 SQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNEL 379
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
+ +K E++ +E + + + + E ++ ++ + L E + + L+ + ++
Sbjct: 380 NSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQ 439
Query: 767 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 588
+ +IE K + N E K+ L++ ++ + ++ +K + N + T+ +
Sbjct: 440 TRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKE 499
Query: 587 EDLNKESKEKQDL--EKRVLE 531
+LNK +EK+ + EK +E
Sbjct: 500 NELNKLKEEKEQIFNEKTTIE 520
>ref|XP_004185542.1| myosin heavy chain, partial [Entamoeba invadens IP1]
gi|440293024|gb|ELP86196.1| myosin heavy chain, partial
[Entamoeba invadens IP1]
Length = 1338
Score = 118 bits (295), Expect = 3e-23
Identities = 159/697 (22%), Positives = 294/697 (42%), Gaps = 54/697 (7%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++D++++ + ++ GK+ L +++ A +IV +++
Sbjct: 652 QEDQEHIEELQGDIKRGKEDLSKLTTEYKKLEADNQGLQDEITEHKATIVKKDSVITELN 711
Query: 2258 QALENKVGDFEAAIATLNDELLNEKD-DKKCIVNDRNIVEADKQA--LENKVADFEA--- 2097
+ +E+K G+ L E N KD + + + +I + +KQ L+N ++D A
Sbjct: 712 KDIEDKEGEISDLKKKLEAEEDNSKDLETQLHEKEDDIADLEKQVKKLQNTISDVNAQNE 771
Query: 2096 -TIATLND---ELLNEKDD-KKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCI 1932
T A LND +L N K+D KK + D E K+ A ++DE +
Sbjct: 772 DTGAVLNDTKDDLANTKNDLKKTQLALDDT--EKKLDQQVAQNKKVSDERDGYNQQLQAE 829
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---LDKRISDLKAD 1761
L +AK A + K++ L + K L D+ RK D +N ++ L KRI D D
Sbjct: 830 KTKTAALTSAKNASDKKISSLNSEKDELEDK-NRKLDSSNKDAQRKIAELTKRIEDGLND 888
Query: 1760 -----APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTAL 1596
A + D E + AL ++ +V I L+E+L +E+ +K L
Sbjct: 889 SDMLKAQKADYEAQIQALKDDMEKTEKDLAGAKSNMNQKDVEINNLNEQLAEEQKEKEEL 948
Query: 1595 IKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELR 1416
AE + + S+L+S+ ++ R++ D L+ + LA + A E+
Sbjct: 949 EAKKKKAENDLADLEDAQSNLQSEKDKTEKD--RKKLDNDLKEALQKLADITAELEKNKA 1006
Query: 1415 KEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 1236
K+ ++ L E + K LE A N++ E++L + K D LT+
Sbjct: 1007 ANKELQAKLDETADN---------KDKLEADAENMNRKKDAQEKQLAQLKADNDNLTKTK 1057
Query: 1235 EGCEAEKQGPE--KTVLDLEPTIPSLN---DALQRDLDRVMAEKQALE-------KRCSD 1092
+A+ + E K L+++ + L + L+++ D A+K+ L K+ +
Sbjct: 1058 SVVDAKLKDAEREKAALNVKTELDQLQQNFNYLKKNADTDAADKKKLNGTVNESNKKIEE 1117
Query: 1091 LEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKE-------------SIMND 951
L AK LT E E+ E D+ KEK+ K+ ++ ND
Sbjct: 1118 LSAKVDELTGVITRREQEVAEANEELETVKKDKFAKEKEAKKLKAENDEIKEKVKNLAND 1177
Query: 950 LDHVKAERQVLESK-------VSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 792
D + +E++ L+ + VS E + LN +++ D EA E L
Sbjct: 1178 KDQLSSEKKKLQDEYDQLNNLVSGHEDETNKLNGSIRKLQRDLEANNTELTELRDRTAKD 1237
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL---LKDI 621
+K++ DLE + D+E + + ++ E +I++LE+A++ L D+ +L KD+
Sbjct: 1238 KKKIADLEQQVQDLEDRPVGTSNIDQTEVIKRDNQIADLEKAVAALKDQNTQLDAAKKDM 1297
Query: 620 NIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
E E+ + K + +K L+ ++ EK
Sbjct: 1298 KKQSVEDASKIENYESQIKALEAQKKMALDDKAEAEK 1334
Score = 80.5 bits (197), Expect = 7e-12
Identities = 102/484 (21%), Positives = 208/484 (42%), Gaps = 16/484 (3%)
Frame = -2
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQ 1752
+ R E A +++K DLEA L DE+E K++ + K+I+ +AD
Sbjct: 599 IEKREAAEKALSEMKFKNVDLEALVQKLKDEIEELKEEIES-------KKITLEEADMKS 651
Query: 1751 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAE 1572
++ ++ + L LE + L +E+ + K T + KD V E
Sbjct: 652 QEDQEHIEELQGDIKRGKEDLSKLTTEYKKLEADNQGLQDEITEHK--ATIVKKDSVITE 709
Query: 1571 PGK------RTVNEIVSHLESKSRSLK--EHFLREEEDEVLERSASNLAIMKAIREEELR 1416
K ++++ LE++ + K E L E+ED++ + + I + +
Sbjct: 710 LNKDIEDKEGEISDLKKKLEAEEDNSKDLETQLHEKEDDIADLEKQVKKLQNTISDVNAQ 769
Query: 1415 KEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 1236
E G + L + + K L+KT L LD E++L ++ +++
Sbjct: 770 NEDTG-AVLNDTKDDLANTKNDLKKTQLA-----LDDT----EKKLDQQVAQNKKVSDER 819
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1056
+G + Q EKT + S +A + + + +EK LE + L++ N +
Sbjct: 820 DGYNQQLQA-EKT---KTAALTSAKNASDKKISSLNSEKDELEDKNRKLDSSN----KDA 871
Query: 1055 EGHEAEIERKLEASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETT 888
+ AE+ +++E L +D L +K D E ++ +D++ + + +S ++ +
Sbjct: 872 QRKIAELTKRIE-DGLNDSDMLKAQKADYEAQIQALKDDMEKTEKDLAGAKSNMNQKDVE 930
Query: 887 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 708
+ LN +L ++ E++ LEA K+ E + DLE +++ + K + +
Sbjct: 931 INNLNEQLAEEQ-------KEKEELEAKKKKAENDLADLEDAQSNLQSEKDKTEKDRKKL 983
Query: 707 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE----LQEDLNKESKEKQDLEKR 540
LK+ + +L + I+ +K K K++ L E + L+ D +++K EK+
Sbjct: 984 DNDLKEALQKLAD-ITAELEKNKAANKELQAKLDETADNKDKLEADAENMNRKKDAQEKQ 1042
Query: 539 VLEL 528
+ +L
Sbjct: 1043 LAQL 1046
Score = 76.3 bits (186), Expect = 1e-10
Identities = 135/646 (20%), Positives = 252/646 (39%), Gaps = 79/646 (12%)
Frame = -2
Query: 2078 DELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAK 1899
DE L KD + +EA K+ L ++ EAA L++ D + + ++ +E K
Sbjct: 578 DEELAAKDKE---IEALKKKLGEEIEKREAAEKALSEMKFKNVDLEALVQKLKDEIEELK 634
Query: 1898 QALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDL-KADAPQRDQEDDMN 1728
+ +E K LE A ++ E ++ I K+ L K ++ K +A + +D++
Sbjct: 635 EEIESKKITLEEADMKSQEDQEHIEELQGDIKRGKEDLSKLTTEYKKLEADNQGLQDEIT 694
Query: 1727 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNE 1548
K + + E I L ++L+ E+D+ L L E + +
Sbjct: 695 EHKATIVKKDSVITELNKDIEDKEGEISDLKKKLEAEEDNSKDLETQLHEKEDDIADLEK 754
Query: 1547 IVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMK--------------------AIRE 1428
V L++ + E+ VL + +LA K +
Sbjct: 755 QVKKLQNTISDVNAQ--NEDTGAVLNDTKDDLANTKNDLKKTQLALDDTEKKLDQQVAQN 812
Query: 1427 EELRKEKDG------------------KSALVENGEGCEAEKQGLEKTVLERRASNLDTM 1302
+++ E+DG K+A + +EK LE + +SN D
Sbjct: 813 KKVSDERDGYNQQLQAEKTKTAALTSAKNASDKKISSLNSEKDELEDKNRKLDSSNKDAQ 872
Query: 1301 DAIHE------------EELRKEKVDK----SALTENGEGCEAEKQGPEKTVLDLEPTIP 1170
I E + L+ +K D AL ++ E E + G + + + I
Sbjct: 873 RKIAELTKRIEDGLNDSDMLKAQKADYEAQIQALKDDMEKTEKDLAGAKSNMNQKDVEIN 932
Query: 1169 SLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTH- 1002
+LN+ L Q++ + + A+K+ E +DLE ++L E + E +RK ++L
Sbjct: 933 NLNEQLAEEQKEKEELEAKKKKAENDLADLEDAQSNL--QSEKDKTEKDRKKLDNDLKEA 990
Query: 1001 -------NDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 843
EL K K + + LD + LE+ +M +L Q DN
Sbjct: 991 LQKLADITAELEKNKAANKELQAKLDETADNKDKLEADAENMNRKKDAQEKQLAQLKADN 1050
Query: 842 EAFLNERDGLEAVKQGL--EKRVLDLEATIHDIEMKTG---KDDDYNEAEKQTLKKRISE 678
+ + ++A + EK L+++ + ++ K+ D + A+K+ L ++E
Sbjct: 1051 DNLTKTKSVVDAKLKDAEREKAALNVKTELDQLQQNFNYLKKNADTDAADKKKLNGTVNE 1110
Query: 677 LEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE----- 513
+ I L+ K +L I EV E E+L K+K EK +L ++ +
Sbjct: 1111 SNKKIEELSAKVDELTGVITRREQEVAEANEELETVKKDKFAKEKEAKKLKAENDEIKEK 1170
Query: 512 -KCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLD 378
K + +D LS+ K+ + D + +LV G +T+ L+
Sbjct: 1171 VKNLANDKDQLSSEKK------KLQDEYDQLNNLVSGHEDETNKLN 1210
>ref|XP_012262786.1| PREDICTED: myosin-2 heavy chain-like isoform X2 [Athalia rosae]
Length = 1620
Score = 117 bits (293), Expect = 5e-23
Identities = 138/628 (21%), Positives = 272/628 (43%), Gaps = 40/628 (6%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEA---AIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
L AAK +N G+ E A+ E + D + + N+ + + A+ L+N++A
Sbjct: 484 LNAAKAEADNLRGEIERLKNALDAAKGEADKLRSDMEKLKNELDKLRAENDQLKNQLAGL 543
Query: 2102 EATIATLNDELLNEKDDKKCI------VEADKQALESKVSVFEAAIATLNDELLNEKDDK 1941
A L E+ KD++ + ++A+ L+++V+ +A + L E K +
Sbjct: 544 TAENERLRGEIDALKDERDKLRNEINALKAENDKLQAEVNKLKAEVERLEAENGRLKAEF 603
Query: 1940 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
+ + ND + L++ L+ +AD E +L E + + A +K +D+ +L A+
Sbjct: 604 QKLKNDYDALKSENDDLKKSLADAEGRIKSLEAE-KANLLNKIAELKNQIDRLQGELAAE 662
Query: 1760 APQRDQ--------EDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
+D + ++ AL+ V +L + L+++L + K
Sbjct: 663 KAAKDAALQELAAIKSELKALLAEMDKLKAERDKLKAAVDDLTKQLSQLNDDLDQLKSKY 722
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREE 1425
AL+ AE K + V L+ ++ LK + ++ NL A +E
Sbjct: 723 AALL-----AENDK--LKGEVDRLKGENDRLKNDL------DKIKAELDNLKAENAKLKE 769
Query: 1424 ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALT 1245
E K K SA +G E + + E E +A + +DA+ K++VDK
Sbjct: 770 ENAKLKKDLSAAESKIKGLENQIKACE----EEKARLRNEIDAL------KDQVDKL--- 816
Query: 1244 ENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1065
G+ AE+ E + +L+ L+ AL+ +LD+V E L+ L+A+N +L
Sbjct: 817 --GKELAAERAAKEAALRELDALKNELS-ALRAELDKVRGENTRLKGELDKLKAENEALK 873
Query: 1064 DNQEGHEAEIER--------------------KLEASNLTHNDELHKEKDDKESIMNDLD 945
+ + E++R KL+ NDE+ + + + + +L+
Sbjct: 874 ADNNKMKGELDRLNAQVAKLLGDIDALKAENAKLKGDLDKLNDEIKALRAENDKLKAELE 933
Query: 944 HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEA 765
+KAE L+ +++ + + L EL + +N+A E ++ L + L+
Sbjct: 934 QMKAENAKLKDQLASAQAEMAKLKEELDKLKSENDALRGELSKMKGELDKLNAEIAKLQK 993
Query: 764 TIHDIEMKTGK---DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 594
+ ++ + K + D AE + L+ ++L+ + L + +KL KD+ ++EV +
Sbjct: 994 DLDALKAENAKLKDELDKLSAENKELRSENAKLKGELDSLKSENEKLKKDLAAAMAEVAK 1053
Query: 593 LQEDLNKESKEKQDLEKRVLELTSKLEK 510
L+EDL+K E L+ ++ S+L+K
Sbjct: 1054 LKEDLDKLQAENDALKAENAKIKSELDK 1081
Score = 114 bits (284), Expect = 5e-22
Identities = 156/673 (23%), Positives = 290/673 (43%), Gaps = 24/673 (3%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
+ D + + N+ + L A L+N++A + N+ N L+A
Sbjct: 516 RSDMEKLKNELDKLRAENDQLKNQLAGLTAENERLRGEIDALKDERDKLRNEINALKAEN 575
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLN 2079
L+ +V +A + L E K + + + ND + ++++ L+ +AD E I +L
Sbjct: 576 DKLQAEVNKLKAEVERLEAENGRLKAEFQKLKNDYDALKSENDDLKKSLADAEGRIKSLE 635
Query: 2078 DE---LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILE 1908
E LLN+ + K ++ + L ++ + +AA+ EL K + K ++ + + L+
Sbjct: 636 AEKANLLNKIAELKNQIDRLQGELAAEKAAKDAAL----QELAAIKSELKALLAEMDKLK 691
Query: 1907 AAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMN 1728
A + L+ V DL + LND+L++ K A++ + DK LK + + E+D
Sbjct: 692 AERDKLKAAVDDLTKQLSQLNDDLDQLKSKYAALLAEN-DK----LKGEVDRLKGENDR- 745
Query: 1727 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG-KRTVN 1551
+ ++ + L E K K++ L KDL AAE K N
Sbjct: 746 ---------------LKNDLDKIKAELDNLKAENAKLKEENAKLKKDLSAAESKIKGLEN 790
Query: 1550 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG 1371
+I + E K+R LR E D L+ L +EL E+ K A + +
Sbjct: 791 QIKACEEEKAR------LRNEID-ALKDQVDKLG-------KELAAERAAKEAALRELDA 836
Query: 1370 CEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL 1191
+ E L + + R N + EL K K + AL + + E V
Sbjct: 837 LKNELSALRAELDKVRGENTRL-----KGELDKLKAENEALKADNNKMKGELDRLNAQVA 891
Query: 1190 DLEPTIPSL---NDALQRDLDRV-------MAEKQALEKRCSDLEAKNASLTDNQEGHEA 1041
L I +L N L+ DLD++ AE L+ ++A+NA L D +A
Sbjct: 892 KLLGDIDALKAENAKLKGDLDKLNDEIKALRAENDKLKAELEQMKAENAKLKDQLASAQA 951
Query: 1040 EIER------KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYST 879
E+ + KL++ N EL K K + + + ++ ++ + L+++ + ++
Sbjct: 952 EMAKLKEELDKLKSENDALRGELSKMKGELDKLNAEIAKLQKDLDALKAENAKLKDELDK 1011
Query: 878 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQT 699
L+ E ++ +N E D L++ + L+K DL A + ++ K +D D +AE
Sbjct: 1012 LSAENKELRSENAKLKGELDSLKSENEKLKK---DLAAAMAEV-AKLKEDLDKLQAENDA 1067
Query: 698 LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ---EDLNKES-KEKQDLEKRVLE 531
LK ++++ + L + +L K ++ +E L+ +DL K++ K K DL+ + E
Sbjct: 1068 LKAENAKIKSELDKLKSENAELQKALDSLKAENARLKSEVDDLKKDNEKLKNDLQNAIAE 1127
Query: 530 LTSKLEKCICGAR 492
+ KL+ G+R
Sbjct: 1128 M-DKLKAESSGSR 1139
Score = 92.4 bits (228), Expect = 2e-15
Identities = 139/646 (21%), Positives = 266/646 (41%), Gaps = 55/646 (8%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVND-----RNIVEADKQALEN 2118
R +++ K A E + +I TL EL + D+ K + R + + K+ +
Sbjct: 101 RELMKGGKVADERVSMVVQRSIETLV-ELTDNVDELKAEIERLKAEIRRLKDLLKECEDR 159
Query: 2117 KVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
++ + T +L K +K + E D L ++ EA IA L +L+ DK
Sbjct: 160 RLTSSTVAVETAPIDL---KPAEKPLAEMDVSDLLQRIKDLEALIAMLRKQLV----DKD 212
Query: 1937 CIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELE------RKKDDNNAIIKKALD 1788
++ND L + L + + + L DE++ +K+DD + + ++L
Sbjct: 213 AVINDLQNQSFDLATENKRLSVDLDQMNVSYKALMDEVKAMKEELKKRDDKVSDLLRSLQ 272
Query: 1787 KRISDLKADAPQRDQEDDMN----ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1620
+L + + D + +L +VS I+ + EE K
Sbjct: 273 ASAIELLGMNRLQSEMDTLKPQLYSLELERDQLVSELGKVRGVVSERNDQIIKILEE--K 330
Query: 1619 EKDDKT---------ALIKDLVAAEPG-KRTVNEIVSHLESKSRSLKEHFLREEEDEVLE 1470
+K K + ++ L+ E KR ++ + + R L E LR++ ++
Sbjct: 331 DKHVKALARTSNIIQSTVEPLMEQEAALKREIDGLKDRIAELERELAE--LRKKLAQLES 388
Query: 1469 RSASNLAIMKAIREEE---------LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRAS 1317
+A +++ I+ E L + D L + +A+K LEK + E R
Sbjct: 389 ENAEIPGLLEKIKNLEDELARLRAQLAEANDRIRELEKEIAELKADKAQLEKDLAEARKE 448
Query: 1316 NLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN-------- 1161
M+ + EE + ++AL E G C AE + K + + +L
Sbjct: 449 ----MEKMREELAAERAAKEAALKELGN-CRAENERLNKELNAAKAEADNLRGEIERLKN 503
Query: 1160 --DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELH 987
DA + + D++ ++ + L+ L A+N L + G AE ER E+
Sbjct: 504 ALDAAKGEADKLRSDMEKLKNELDKLRAENDQLKNQLAGLTAENERL--------RGEID 555
Query: 986 KEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 807
KD+++ + N+++ +KAE L+++V+ ++ L E + + + N+ D L++
Sbjct: 556 ALKDERDKLRNEINALKAENDKLQAEVNKLKAEVERLEAENGRLKAEFQKLKNDYDALKS 615
Query: 806 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAI-----SILTDKA 642
L+K + D E I + EAEK L +I+EL+ I + +KA
Sbjct: 616 ENDDLKKSLADAEGRIKSL-----------EAEKANLLNKIAELKNQIDRLQGELAAEKA 664
Query: 641 KK--LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
K L+++ SE+ L +++K E+ L+ V +LT +L +
Sbjct: 665 AKDAALQELAAIKSELKALLAEMDKLKAERDKLKAAVDDLTKQLSQ 710
>ref|XP_012262776.1| PREDICTED: major antigen-like isoform X1 [Athalia rosae]
Length = 1710
Score = 117 bits (293), Expect = 5e-23
Identities = 138/628 (21%), Positives = 272/628 (43%), Gaps = 40/628 (6%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEA---AIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
L AAK +N G+ E A+ E + D + + N+ + + A+ L+N++A
Sbjct: 574 LNAAKAEADNLRGEIERLKNALDAAKGEADKLRSDMEKLKNELDKLRAENDQLKNQLAGL 633
Query: 2102 EATIATLNDELLNEKDDKKCI------VEADKQALESKVSVFEAAIATLNDELLNEKDDK 1941
A L E+ KD++ + ++A+ L+++V+ +A + L E K +
Sbjct: 634 TAENERLRGEIDALKDERDKLRNEINALKAENDKLQAEVNKLKAEVERLEAENGRLKAEF 693
Query: 1940 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
+ + ND + L++ L+ +AD E +L E + + A +K +D+ +L A+
Sbjct: 694 QKLKNDYDALKSENDDLKKSLADAEGRIKSLEAE-KANLLNKIAELKNQIDRLQGELAAE 752
Query: 1760 APQRDQ--------EDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
+D + ++ AL+ V +L + L+++L + K
Sbjct: 753 KAAKDAALQELAAIKSELKALLAEMDKLKAERDKLKAAVDDLTKQLSQLNDDLDQLKSKY 812
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREE 1425
AL+ AE K + V L+ ++ LK + ++ NL A +E
Sbjct: 813 AALL-----AENDK--LKGEVDRLKGENDRLKNDL------DKIKAELDNLKAENAKLKE 859
Query: 1424 ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALT 1245
E K K SA +G E + + E E +A + +DA+ K++VDK
Sbjct: 860 ENAKLKKDLSAAESKIKGLENQIKACE----EEKARLRNEIDAL------KDQVDKL--- 906
Query: 1244 ENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLT 1065
G+ AE+ E + +L+ L+ AL+ +LD+V E L+ L+A+N +L
Sbjct: 907 --GKELAAERAAKEAALRELDALKNELS-ALRAELDKVRGENTRLKGELDKLKAENEALK 963
Query: 1064 DNQEGHEAEIER--------------------KLEASNLTHNDELHKEKDDKESIMNDLD 945
+ + E++R KL+ NDE+ + + + + +L+
Sbjct: 964 ADNNKMKGELDRLNAQVAKLLGDIDALKAENAKLKGDLDKLNDEIKALRAENDKLKAELE 1023
Query: 944 HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEA 765
+KAE L+ +++ + + L EL + +N+A E ++ L + L+
Sbjct: 1024 QMKAENAKLKDQLASAQAEMAKLKEELDKLKSENDALRGELSKMKGELDKLNAEIAKLQK 1083
Query: 764 TIHDIEMKTGK---DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 594
+ ++ + K + D AE + L+ ++L+ + L + +KL KD+ ++EV +
Sbjct: 1084 DLDALKAENAKLKDELDKLSAENKELRSENAKLKGELDSLKSENEKLKKDLAAAMAEVAK 1143
Query: 593 LQEDLNKESKEKQDLEKRVLELTSKLEK 510
L+EDL+K E L+ ++ S+L+K
Sbjct: 1144 LKEDLDKLQAENDALKAENAKIKSELDK 1171
Score = 114 bits (284), Expect = 5e-22
Identities = 156/673 (23%), Positives = 290/673 (43%), Gaps = 24/673 (3%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
+ D + + N+ + L A L+N++A + N+ N L+A
Sbjct: 606 RSDMEKLKNELDKLRAENDQLKNQLAGLTAENERLRGEIDALKDERDKLRNEINALKAEN 665
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLN 2079
L+ +V +A + L E K + + + ND + ++++ L+ +AD E I +L
Sbjct: 666 DKLQAEVNKLKAEVERLEAENGRLKAEFQKLKNDYDALKSENDDLKKSLADAEGRIKSLE 725
Query: 2078 DE---LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILE 1908
E LLN+ + K ++ + L ++ + +AA+ EL K + K ++ + + L+
Sbjct: 726 AEKANLLNKIAELKNQIDRLQGELAAEKAAKDAAL----QELAAIKSELKALLAEMDKLK 781
Query: 1907 AAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMN 1728
A + L+ V DL + LND+L++ K A++ + DK LK + + E+D
Sbjct: 782 AERDKLKAAVDDLTKQLSQLNDDLDQLKSKYAALLAEN-DK----LKGEVDRLKGENDR- 835
Query: 1727 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG-KRTVN 1551
+ ++ + L E K K++ L KDL AAE K N
Sbjct: 836 ---------------LKNDLDKIKAELDNLKAENAKLKEENAKLKKDLSAAESKIKGLEN 880
Query: 1550 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG 1371
+I + E K+R LR E D L+ L +EL E+ K A + +
Sbjct: 881 QIKACEEEKAR------LRNEID-ALKDQVDKLG-------KELAAERAAKEAALRELDA 926
Query: 1370 CEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL 1191
+ E L + + R N + EL K K + AL + + E V
Sbjct: 927 LKNELSALRAELDKVRGENTRL-----KGELDKLKAENEALKADNNKMKGELDRLNAQVA 981
Query: 1190 DLEPTIPSL---NDALQRDLDRV-------MAEKQALEKRCSDLEAKNASLTDNQEGHEA 1041
L I +L N L+ DLD++ AE L+ ++A+NA L D +A
Sbjct: 982 KLLGDIDALKAENAKLKGDLDKLNDEIKALRAENDKLKAELEQMKAENAKLKDQLASAQA 1041
Query: 1040 EIER------KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYST 879
E+ + KL++ N EL K K + + + ++ ++ + L+++ + ++
Sbjct: 1042 EMAKLKEELDKLKSENDALRGELSKMKGELDKLNAEIAKLQKDLDALKAENAKLKDELDK 1101
Query: 878 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQT 699
L+ E ++ +N E D L++ + L+K DL A + ++ K +D D +AE
Sbjct: 1102 LSAENKELRSENAKLKGELDSLKSENEKLKK---DLAAAMAEV-AKLKEDLDKLQAENDA 1157
Query: 698 LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ---EDLNKES-KEKQDLEKRVLE 531
LK ++++ + L + +L K ++ +E L+ +DL K++ K K DL+ + E
Sbjct: 1158 LKAENAKIKSELDKLKSENAELQKALDSLKAENARLKSEVDDLKKDNEKLKNDLQNAIAE 1217
Query: 530 LTSKLEKCICGAR 492
+ KL+ G+R
Sbjct: 1218 M-DKLKAESSGSR 1229
Score = 92.4 bits (228), Expect = 2e-15
Identities = 139/646 (21%), Positives = 266/646 (41%), Gaps = 55/646 (8%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVND-----RNIVEADKQALEN 2118
R +++ K A E + +I TL EL + D+ K + R + + K+ +
Sbjct: 191 RELMKGGKVADERVSMVVQRSIETLV-ELTDNVDELKAEIERLKAEIRRLKDLLKECEDR 249
Query: 2117 KVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
++ + T +L K +K + E D L ++ EA IA L +L+ DK
Sbjct: 250 RLTSSTVAVETAPIDL---KPAEKPLAEMDVSDLLQRIKDLEALIAMLRKQLV----DKD 302
Query: 1937 CIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELE------RKKDDNNAIIKKALD 1788
++ND L + L + + + L DE++ +K+DD + + ++L
Sbjct: 303 AVINDLQNQSFDLATENKRLSVDLDQMNVSYKALMDEVKAMKEELKKRDDKVSDLLRSLQ 362
Query: 1787 KRISDLKADAPQRDQEDDMN----ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1620
+L + + D + +L +VS I+ + EE K
Sbjct: 363 ASAIELLGMNRLQSEMDTLKPQLYSLELERDQLVSELGKVRGVVSERNDQIIKILEE--K 420
Query: 1619 EKDDKT---------ALIKDLVAAEPG-KRTVNEIVSHLESKSRSLKEHFLREEEDEVLE 1470
+K K + ++ L+ E KR ++ + + R L E LR++ ++
Sbjct: 421 DKHVKALARTSNIIQSTVEPLMEQEAALKREIDGLKDRIAELERELAE--LRKKLAQLES 478
Query: 1469 RSASNLAIMKAIREEE---------LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRAS 1317
+A +++ I+ E L + D L + +A+K LEK + E R
Sbjct: 479 ENAEIPGLLEKIKNLEDELARLRAQLAEANDRIRELEKEIAELKADKAQLEKDLAEARKE 538
Query: 1316 NLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN-------- 1161
M+ + EE + ++AL E G C AE + K + + +L
Sbjct: 539 ----MEKMREELAAERAAKEAALKELGN-CRAENERLNKELNAAKAEADNLRGEIERLKN 593
Query: 1160 --DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELH 987
DA + + D++ ++ + L+ L A+N L + G AE ER E+
Sbjct: 594 ALDAAKGEADKLRSDMEKLKNELDKLRAENDQLKNQLAGLTAENERL--------RGEID 645
Query: 986 KEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 807
KD+++ + N+++ +KAE L+++V+ ++ L E + + + N+ D L++
Sbjct: 646 ALKDERDKLRNEINALKAENDKLQAEVNKLKAEVERLEAENGRLKAEFQKLKNDYDALKS 705
Query: 806 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAI-----SILTDKA 642
L+K + D E I + EAEK L +I+EL+ I + +KA
Sbjct: 706 ENDDLKKSLADAEGRIKSL-----------EAEKANLLNKIAELKNQIDRLQGELAAEKA 754
Query: 641 KK--LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
K L+++ SE+ L +++K E+ L+ V +LT +L +
Sbjct: 755 AKDAALQELAAIKSELKALLAEMDKLKAERDKLKAAVDDLTKQLSQ 800
>ref|XP_009292629.1| PREDICTED: nesprin-1 isoform X7 [Danio rerio]
Length = 14457
Score = 116 bits (291), Expect = 8e-23
Identities = 145/673 (21%), Positives = 300/673 (44%), Gaps = 29/673 (4%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I +L+ + + K D++ N+R +++ K LE + + E
Sbjct: 4857 IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKI 4916
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + + K I +D++
Sbjct: 4917 KLETQHDR--QRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKD 4974
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-R 1749
+LE K LE ++L K ++LE++K++ A I+K L+K ++ + + +
Sbjct: 4975 MLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQIQKEREDLEKMNENITREMHEIK 5030
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLV 1581
QE+ MN + L+ I L +EL+KEK+ ++ L +
Sbjct: 5031 HQEEQMNQ--------------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQS 5076
Query: 1580 AAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
+ + +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+L+ K
Sbjct: 5077 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKL 5136
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTEN 1239
K + E E K LE+ + R +T + EEL+KE+ D + L E+
Sbjct: 5137 QKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED 5196
Query: 1238 GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+ EK ++ + E ++ L Q++ + K+ + K+ D+E + D
Sbjct: 5197 ---TKREKNSLDEMKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DK 5245
Query: 1058 QEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYST 879
E E+E+ L+A E+HK++ + E + +++ ER + V D+++ +
Sbjct: 5246 IRLREDELEQ-LQA-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIIS 5294
Query: 878 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDD 723
L+ + + D EAF NE++ L+ +K LE+ ++E T H+ EM +
Sbjct: 5295 LDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMET 5354
Query: 722 YNEAEKQTLKKRI------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 561
N KQ K ++ E+E+ + K L +D+ + ++ L+E+ NK +
Sbjct: 5355 MNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQM 5414
Query: 560 KQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPL 381
K LE+ E+ SK+++ R L + A + E L + RK L
Sbjct: 5415 KIGLEREADEI-SKIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVL 5464
Query: 380 DITKTCDAVDISE 342
D K + +++
Sbjct: 5465 DKIKVANESTLAD 5477
Score = 114 bits (286), Expect = 3e-22
Identities = 160/701 (22%), Positives = 304/701 (43%), Gaps = 57/701 (8%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAA 2262
EKDD ++ D + + L E+A+A +S+ ++++
Sbjct: 3517 EKDDLAHLAEDTKRKDDEMKVLH------ESALADIQKEKCNLEQMRESMFKQNEMIDSE 3570
Query: 2261 KQAL---ENKVGDFEAAIATLNDELLNEKDDKKCIV-NDRNIVEADKQALENKVADFEAT 2094
K+ + E+K+ +A I E+ D KK I+ N+R + Q L ++
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEM----DTKKSIIENERAAMTKKNQDLMTELTKQSED 3626
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ E+L EK+ ++E+D++ L+ V + + + + + K D++ + N++ +
Sbjct: 3627 VEIQMKEVLTEKE----LLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEV 3682
Query: 1913 LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---------LDKRISDLKAD 1761
L+ K L+ + ++E K E +R ++ I K + + I D+K
Sbjct: 3683 LKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQ 3742
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 3743 EKQMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL- 3781
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ +E+ + + +E+
Sbjct: 3782 -DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1248
L+ K K E EK LE K LER A + + +EE++ E+ +
Sbjct: 3841 LKMMKLQKQVF-------EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKM 3889
Query: 1247 TENGEGCE------AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
TE + + AE E+ +LD ++ SL LQ++ ++ + K+ D+
Sbjct: 3890 TEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDV 3949
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESK 909
E K +N E E+ R+L+A E+ KEK + ES ER +
Sbjct: 3950 ENKK----ENLRLREDEL-RQLQAEIHKQQREIEKEKINIES----------ERAAIIKD 3994
Query: 908 VSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---- 753
V D++ L+ + + D EAF NE++ L+ +K LE+ ++E T HD
Sbjct: 3995 VEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRV 4054
Query: 752 ----IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AKKLLKDINIWL 609
+++ +D+ N E+ L ++ ++EE I SI +DK +K D+
Sbjct: 4055 EEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTR 4114
Query: 608 SEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 4115 SELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 4155
Score = 113 bits (282), Expect = 9e-22
Identities = 133/674 (19%), Positives = 288/674 (42%), Gaps = 31/674 (4%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
K D++ + N++ +L+ K L+ + + E I DR L+
Sbjct: 3670 KQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMN 3729
Query: 2258 QALENKVGDF---EAAIATLNDELLNEKDD----KKCIVNDRNIVEADKQALENKVADFE 2100
+ ++ D E + DEL K + ++ + ++ I+ D+ L+ K ++ +
Sbjct: 3730 DNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELD 3789
Query: 2099 ATIATLNDELLNEKDDKKCI------VEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ND + K+++K + +E K+ +E + F+ +L+++L K K+
Sbjct: 3790 KQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQ 3849
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
++N LE K LE + ++ K + +E +++L+K +LK
Sbjct: 3850 VFEEEKNKLEQMKIELEREAGEIRKIKEEIQNE------------RQSLEKMTEELK--- 3894
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
R++E + +I+ ++V L ELQKEK + + +++
Sbjct: 3895 --REKESFTHLA--------EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK 3944
Query: 1577 AEPGKRTVNEIVSHLESKSRSLKEHF---LREEEDEVLERSASNLAIMKAIREEELR--- 1416
E + E + R L+ RE E E + + AI+K + + + +
Sbjct: 3945 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 4004
Query: 1415 KEKDGKSALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTE 1242
++D +S ++ E E EK+ L+ KT LER A ++ + E + +++V++ A
Sbjct: 4005 LDRDAESLKLDR-EAFENEKEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQI 4061
Query: 1241 NGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD 1062
+ E E D+ + N ++ + + ++K LEK DLE + L
Sbjct: 4062 QKDRDEINNLIEETNRKDM--VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYK 4119
Query: 1061 NQEGHEAEIERKLEASNLTHNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDME 894
+E E + E L E+ KE++D E+I ++ +K + + + K +++
Sbjct: 4120 VKEDLEKQKENTLA--------EIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELD 4171
Query: 893 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKR---VLDLEATIHDIEMKTGKDDD 723
+ + N Q+ + E + +R L+ + L+K+ + D+ T+ + + KD +
Sbjct: 4172 QLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKE 4231
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE---DLNKESKEKQD 552
E +KQ ++K ++++ L + KK+ ++ E +L++ +L +E+ E
Sbjct: 4232 EMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISK 4291
Query: 551 LEKRVLELTSKLEK 510
+++ +LEK
Sbjct: 4292 IKEETQNKRQRLEK 4305
Score = 110 bits (275), Expect = 6e-21
Identities = 135/650 (20%), Positives = 282/650 (43%), Gaps = 65/650 (10%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ + + + + + +ND + K+++K + D+ +E KQ +E + D
Sbjct: 4643 EKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHD 4702
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
F+ + +L+ +L K K+ E + + K+ + A + +
Sbjct: 4703 FDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKM 4762
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1806
+EL EK+ + D + IL+ K A E +ADL+ K+ L + E +
Sbjct: 4763 TEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDV 4822
Query: 1805 IKKALDKRISD-----LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1641
K + R+ + L+A+ ++ +E + + I+ N+E +
Sbjct: 4823 ENKKENLRLREDELWQLQAEIYKQQREIEKEKI--------NIESERAAIIKNVED---L 4871
Query: 1640 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE------ 1479
H+ + ++D + +L D A E + + ++ + LE ++ +++ L + D
Sbjct: 4872 QHKIISLDRDSE-SLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEM 4930
Query: 1478 ----VLERSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---- 1338
+R N I + R++ + EK+ ++ + + E EK LEKT
Sbjct: 4931 TAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSEL 4990
Query: 1337 -----VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEP 1179
LE++ N T+ I +E EK++++ E E E+Q +K + L+
Sbjct: 4991 YKVKEDLEKQKEN--TLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 5048
Query: 1178 TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLT 1005
I +L L+++ + +M + L++R S+L+ + ++ D E + E ++ K +
Sbjct: 5049 EIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5108
Query: 1004 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 837
E+ KE+D+ ++S+ DL +K ++QV+E + + +E L E E
Sbjct: 5109 QKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEE 5168
Query: 836 FLNERDGLEAVKQGLEKRVLDLEATIHDI--------EMKTGKDDDYNEAEKQTLKKRIS 681
N+R LE + + L+K D+ D EMK + + +K+ K +
Sbjct: 5169 TQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKE--KSNLE 5226
Query: 680 ELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 531
E++E IS T+ +K I + E+ +LQ +++K+ E ++EK +E
Sbjct: 5227 EMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSE-TEIEKSNIE 5275
Score = 108 bits (270), Expect = 2e-20
Identities = 151/639 (23%), Positives = 281/639 (43%), Gaps = 55/639 (8%)
Frame = -2
Query: 2261 KQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL 2082
K+ L N + L +L++ + D K + DR E +K+A++ D + +
Sbjct: 4437 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 4496
Query: 2081 NDELLNEKDDKKCIVEADKQALESKVSVFEAAIAT-LNDELLNEKDDK-----KCIVNDR 1920
L + D++ + E Q + + + T D +LNEK+ K I +D+
Sbjct: 4497 EKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDK 4556
Query: 1919 NILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
++LE + LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 4557 DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM-NENITREMHEIKHQ 4615
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q +Q+ D + L+ I L +EL+KEK+ D++
Sbjct: 4616 EEQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQF- 4654
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ + + +++
Sbjct: 4655 -DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKD 4713
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-----EELRKEKVDK 1257
L+ K K E E K LE+ E R +T + EEL+KEK
Sbjct: 4714 LKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESF 4773
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1077
+ L E+ + E+ +LD + N++L DL + EK LE+ ++ +
Sbjct: 4774 THLAEDTK--------KEQEILD---KVKVANESLMADLQK---EKSNLEEMRENISKQT 4819
Query: 1076 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
+ + +E + +L+A E+ KEK + ES ER + V
Sbjct: 4820 EDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIES----------ERAAIIKNVE 4869
Query: 902 DMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEM 744
D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T HD +E
Sbjct: 4870 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 4929
Query: 743 KTG---KD-DDYNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSE 603
T KD D N ++T L ++ ++E+ I SI +DK +K D+ SE
Sbjct: 4930 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSE 4989
Query: 602 VTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 4990 LYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHE 5028
Score = 104 bits (259), Expect = 4e-19
Identities = 127/622 (20%), Positives = 279/622 (44%), Gaps = 40/622 (6%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I L+ + + K D++ N++ +++ K LE + + E
Sbjct: 3984 IESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKI 4043
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + ++ K I +D++
Sbjct: 4044 KLETQHDR--QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 4101
Query: 1916 ILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+LE K LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 4102 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKM-NENITREMHEIKHQE 4160
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIK 1590
Q +Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 4161 EQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL-- 4198
Query: 1589 DLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+
Sbjct: 4199 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQ 4258
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKT------VLERRASNLDTMDAIHEEELRKE---- 1269
+K K K E E K LE+ + E + ++ + EE +R++
Sbjct: 4259 KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLA 4318
Query: 1268 ------KVDKSALTEN---GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1116
K +K L E E A+ Q + + ++ I L + + + ++ +
Sbjct: 4319 HLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLRED 4378
Query: 1115 ALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNLTHNDELHKEKDDKE----SIMND 951
L+K ++++ + + + + E+E + E N+ EL K+ +D E I+ +
Sbjct: 4379 ELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMM--TELKKKSEDVEIQMKEILTE 4436
Query: 950 LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 771
+ + +R++L V +++ L + ++ D EAF NE++ ++ +K L+ + ++
Sbjct: 4437 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 4496
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE-VTE 594
E I+++T D E ++K ++ I T++ +L + N + E +
Sbjct: 4497 E----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE-ETNRKDMVLNEKNRDIEEKIKS 4551
Query: 593 LQEDLNKESKEKQDLEKRVLEL 528
+Q D + KE+ +LEK EL
Sbjct: 4552 IQSDKDMLEKERHNLEKTRSEL 4573
Score = 100 bits (250), Expect = 5e-18
Identities = 127/675 (18%), Positives = 292/675 (43%), Gaps = 46/675 (6%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ + +++++L K L+N+ + + ++ +++ +
Sbjct: 10680 ERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEE 10739
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N++ + + + + +R + + L+ ++ +F+A ++ +E
Sbjct: 10740 TRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEE 10799
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L ++ + K E K E+K ++ E +E+ EK+ ++ R +E ++
Sbjct: 10800 DLPKEKEMK---EDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKE 10856
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNAL 1722
+E + LE ++ ++ E ++ DD I K+ L+K S++ Q ++E +++
Sbjct: 10857 IEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKK 10916
Query: 1721 IXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK-----------DDKTALIKDLVAA 1575
I +IV L V + E+Q +K D++ LI++ +
Sbjct: 10917 IKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQ 10976
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEEL 1419
+ + E+ ++ + +LKE + +EE + V+E R +L M E+
Sbjct: 10977 QNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQK 11036
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI-----------HEEELRK 1272
+ + + L + E E+ + T L++R +T I +E+L++
Sbjct: 11037 QDLMNQRDLLKQ-----EREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQ 11091
Query: 1271 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1092
+ ++ E E + E + ++ D L+++ E++ L+K+ D
Sbjct: 11092 AIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADD 11151
Query: 1091 LEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAE 930
LE + D +E + + E+KL + +N L D+L KEK+D N+LD ++ E
Sbjct: 11152 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 11211
Query: 929 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEAT 762
Q ++++ +++ T E+ ++ E LN ER LE V+ EK +
Sbjct: 11212 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQ 11267
Query: 761 IHDIEMKTGKD-DDYNEAEKQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
I ++ +KT + D+ ++ + L +K ++ I +L + ++ +++ ++ EL
Sbjct: 11268 IEEMRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEEL 11324
Query: 590 QEDLNKESKEKQDLE 546
+ + K EK+DLE
Sbjct: 11325 KLEKQKIQNEKKDLE 11339
Score = 100 bits (248), Expect = 8e-18
Identities = 135/693 (19%), Positives = 298/693 (43%), Gaps = 107/693 (15%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ +E KQ +E + +
Sbjct: 5060 EKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDN 5119
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
+ + +L+++L K K+ I E + + K+ + A + +
Sbjct: 5120 MDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKM 5179
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------EL 1836
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++
Sbjct: 5180 AEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDI 5239
Query: 1835 ERKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXX 1698
E++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 5240 EKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDA 5299
Query: 1697 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LE 1530
+ N + + + EL++E D+ + K + + ++ V E+ + +
Sbjct: 5300 ESLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMN 5356
Query: 1529 SKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQ 1353
++ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K
Sbjct: 5357 NERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKI 5416
Query: 1352 GLE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEA 1221
GLE K + NL+ M +A+ EE E++++ + E A
Sbjct: 5417 GLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLA 5476
Query: 1220 EKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA 1041
+ Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+
Sbjct: 5477 DLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIES 5536
Query: 1040 EIERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E + E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 5537 ERAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSI 5594
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK----- 732
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 5595 ERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKER 5654
Query: 731 -----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 609
D+ Y E EK+ ++ S+LE+A S + K K+I I L
Sbjct: 5655 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIAL 5710
Query: 608 SEVTELQEDLNKESKE------KQDLEKRVLEL 528
+E+ + + L K SKE K + EK+ ++L
Sbjct: 5711 AEIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 5743
Score = 99.4 bits (246), Expect = 1e-17
Identities = 138/664 (20%), Positives = 294/664 (44%), Gaps = 74/664 (11%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R+++E ++ + + + N +L+N++D K +R + L+ ++ +F
Sbjct: 10178 RSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLK---QEREEINHKWTQLQQRIDEF 10234
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+A ++ +E L ++ K + E K E+K+ + E T +++ EK+ ++ V
Sbjct: 10235 DAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVM- 10290
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
R +E K+ L+ + LE ++ ++ E ++ DD I K+ L+K S++ Q
Sbjct: 10291 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 10350
Query: 1748 DQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEV-------NILILHEEL----QKEKDDK 1605
++E +++ I +IV L V +I + EEL QK D++
Sbjct: 10351 EEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQ 10410
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE---HFLREEED-------------EVL 1473
++++ + + E+ ++ + +LKE H +E+E+ E L
Sbjct: 10411 GLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDL 10470
Query: 1472 ERSASNLA-----------IMKAIREE------ELRKEKDGKSALVENGEGCEAEKQGLE 1344
E+ ++++ ++K REE +L++ D A V + + KQ
Sbjct: 10471 EKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQ--- 10527
Query: 1343 KTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 1170
K + E R S +T I E + + E K+ K E E A+ + ++ + ++ +
Sbjct: 10528 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLE 10587
Query: 1169 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHN 999
+ + + ++ +K+ +E+ DLE + + ++ E +E+E K+ + +
Sbjct: 10588 RVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKC 10647
Query: 998 D-ELHKE---------KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 849
D E KE ++ K I + + ERQ + + + S L NE ++ +
Sbjct: 10648 DIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKN 10707
Query: 848 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD-----DYNEAEKQTLKKRI 684
NE ER+ L+ ++ LEK ++++ E + K+D + +KQ L+ +
Sbjct: 10708 INEVIKKERETLKEMEAYLEKEKEEMKSITE--ETRRQKEDLEKMSTHINEQKQDLRSQR 10765
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVT-ELQEDLNKESKEKQD------LEKRVLELT 525
LE+ + K K+L + I+ + ++V+ + +EDL KE + K+D + +LE+
Sbjct: 10766 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK 10825
Query: 524 SKLE 513
+K E
Sbjct: 10826 TKAE 10829
Score = 98.2 bits (243), Expect = 3e-17
Identities = 142/710 (20%), Positives = 297/710 (41%), Gaps = 62/710 (8%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ ++ DR+ L+ + L+ + + + T + N+R L+ K+
Sbjct: 4187 EKEIIMKDRSQLDLRQSELDKQQTNMNDIMET--------------MKNERKQLDKDKEE 4232
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE--------- 2100
+E + + E ++ + +D+K + + + E +K LE + E
Sbjct: 4233 MEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKI 4292
Query: 2099 --------ATIATLNDELLNEKDD----------KKCIVEADKQALESKVSVFEAAIATL 1974
+ + +EL+ EK+ +K I++ K A ES ++ + + L
Sbjct: 4293 KEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL 4352
Query: 1973 NDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 1794
+ N K+ I N++ + + L+ +++ ++ ++ E + + A+I++
Sbjct: 4353 EEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREK 4412
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
+++LK + D E M ++ + V NL+ ++ L + ++ K
Sbjct: 4413 -QNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLK 4469
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV---LERSASNLAIM 1443
D+ A + A + K + +E + R EE ER N I
Sbjct: 4470 LDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIE 4529
Query: 1442 KAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---------VLERRASNLDT 1305
+ R++ + EK+ ++ + + E E+ LEKT LE++ N T
Sbjct: 4530 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN--T 4587
Query: 1304 MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEPTIPSLNDALQRDLDRV 1131
+ I +E EK++++ E E E+Q +K + L+ I +L L+++ + +
Sbjct: 4588 LAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 4647
Query: 1130 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----K 969
M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D +
Sbjct: 4648 MKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSR 4707
Query: 968 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 789
+S+ DL +K ++QV E + + +E L E + E NER LE + + L+
Sbjct: 4708 KSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELK 4767
Query: 788 KRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILTDKAK 639
K + E+ H E T K+ + NE A+ Q K + E+ E IS T+ +
Sbjct: 4768 K---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVE 4823
Query: 638 KLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 489
+++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 4824 NKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 4870
Score = 94.7 bits (234), Expect = 3e-16
Identities = 125/616 (20%), Positives = 275/616 (44%), Gaps = 31/616 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGD-------FEAAIATLNDELLNEKDDKKCIVNDRNIVEA 2139
S+ + ++ K+ L+ + D FE I + EL E ++ I + +E
Sbjct: 2366 SLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAEN---IERKKKELEI 2422
Query: 2138 DKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDE-- 1965
K A+ + E + +E D+ + + AD +E + S ++ E
Sbjct: 2423 QKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEES 2482
Query: 1964 -LLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1800
+ EKD K N++N+ L A + L+ + A++E K L + ++R + + I K
Sbjct: 2483 YVKKEKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITK 2542
Query: 1799 KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1620
+ +R+++++ + +++ D+ + ++E + IL+ EL+K
Sbjct: 2543 EK--QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEK 2588
Query: 1619 EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMK 1440
K+ KT L ++ A + K + + + L L ++E E E+ ++ +
Sbjct: 2589 IKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDR 2642
Query: 1439 AIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD 1260
EE + K ++ K + + + E+ L + +R S+ DT++ +L K K +
Sbjct: 2643 RNNEEMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTE 2700
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK 1080
L + + E Q + + +E I + L++ + +K+ LEK E +
Sbjct: 2701 MKDLEK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKE 2753
Query: 1079 NASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSD 900
A ++ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E +
Sbjct: 2754 KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 899 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDD 726
+E + ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D+
Sbjct: 2814 IE----QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDE 2866
Query: 725 DYN--------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDL 579
+ N E+++ TL+K +L++ + + D K+L + I L+E+ + +E L
Sbjct: 2867 EANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREIL 2926
Query: 578 NK----ESKEKQDLEK 543
+ SK+K+DLEK
Sbjct: 2927 EQLKLTLSKQKEDLEK 2942
Score = 94.4 bits (233), Expect = 4e-16
Identities = 139/601 (23%), Positives = 252/601 (41%), Gaps = 10/601 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR-------NIVEADKQAL 2124
+N +E K+ L+N + E + +L E N +D+K + R N + +++ L
Sbjct: 8113 KNQIEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDL 8172
Query: 2123 ENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVF--EAAIATLNDELLNEK 1950
EN + E + +E + ++ I + D + +S+ ++ E I +ELL K
Sbjct: 8173 ENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMK 8232
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL 1770
+ + + +E Q L+ DLE AK E++R++D II + ++ ++
Sbjct: 8233 VE---MGRTKEEIEKESQRLQDATIDLENAKA----EIQRQEDKFEDIIDIKIQEKEREI 8285
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1590
K Q D+E + V +LE+ + + + Q+ +D K L K
Sbjct: 8286 KI---QLDKETKRLS------------EEIELKVKDLEMEMADMKRQKQEIEDTKGLLEK 8330
Query: 1589 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ K+ + + LE + L RE+++ ER+ NL +K + E+LRKE
Sbjct: 8331 E-------KQELKQEKKELEDQMMDLT----REKQETEEERN--NLMALKN-QLEDLRKE 8376
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ EK LEK+ +E + ++++ + K +K +L +
Sbjct: 8377 NE-----------IVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRFE 8425
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
E +KQ E + + + D L R+L + K LEK + N+E
Sbjct: 8426 TEQQKQMLEISTTKMMEEKNEMAD-LSRELQKA---KDELEK---------IAYKTNKER 8472
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 870
HE E +++A ELH + + ++ + Q+++ K + +E ++
Sbjct: 8473 HEVE---QMQA-------ELHSQ----------IQAIEQQGQIMQDKQNHLEEKELSIQR 8512
Query: 869 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKK 690
+ ++ N F E++ L V + KR DLE DIE+ K N + + L+K
Sbjct: 8513 KEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEK 8568
Query: 689 RISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLE 513
SELE D+ IW + L E L + KEK+ LEK +EL SK E
Sbjct: 8569 IRSELENE-----------KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKRE 8617
Query: 512 K 510
+
Sbjct: 8618 Q 8618
Score = 94.4 bits (233), Expect = 4e-16
Identities = 135/648 (20%), Positives = 285/648 (43%), Gaps = 52/648 (8%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVE--------- 2142
I +RN LE K L + E + L+ ++ +K I ++ IVE
Sbjct: 8924 IEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQ 8983
Query: 2141 -------ADKQALENK-VADFEATIATLNDELLNEKDDKKCIVEADK------QALESKV 2004
++ ALE + + D + +A EL N+ + + + EA K + E+ +
Sbjct: 8984 RNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHL 9043
Query: 2003 SVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN---DELE 1833
+ I ++ +E +K+D + I N+ KQ L+ K LE + +N + +
Sbjct: 9044 QRDKKEIKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQ 9100
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1653
++ D+ +A ++K ++ +++ K +R +++N I ++
Sbjct: 9101 QRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHE---INQKIE 9157
Query: 1652 NILILHEELQKEKDDKTAL-IKDLVAAEPGKRTVNEIV---SHLESKSRSLKEHF-LREE 1488
+ L E++ KEK+ A+ IK + E + +E+V + ++ + + L + + E+
Sbjct: 9158 ELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQ 9217
Query: 1487 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1308
E E LE+ S + K E+E R E D K + + EK +EK+ +
Sbjct: 9218 EKEDLEKMKSEIMTQKQEMEKE-RSELDNKI------QQTDLEKHDIEKSKEIVEKLMFE 9270
Query: 1307 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL--------DLEPTIPSLNDAL 1152
+ HE +L+KE++D E +K E+ +L + I ++N+ +
Sbjct: 9271 VEEQRHEIQLQKEELD----------IERQKIADEQDLLIQNKSELQNENERIRNINEVI 9320
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 972
+++ + + + LEK +++ S+T+ + ++E K+ N +L K++D
Sbjct: 9321 KKERETLKEMEAHLEKEKEEMK----SITEETRRQKEDLE-KMSTDIKEQNQDLMKQRDL 9375
Query: 971 KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 792
E D++H E L+ ++ + + + ++ + ++ + + ER LE K
Sbjct: 9376 LEQEKEDINH---EWTQLQQRIDEFD---AQVSKQKEEDLTKQKEMKEERKSLEETK--- 9426
Query: 791 EKRVLDL--EATIHDIEMKTGKDDDYN------EAEKQTLKKRISELEEAISILTDKAKK 636
R++++ +A + DI+ + K+++ E + + L + SEL+ S + + KK
Sbjct: 9427 -ARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKK 9485
Query: 635 LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK-----LEKC 507
L D I E L++ ++ K++Q +E+ EL +K +EKC
Sbjct: 9486 LNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKC 9533
Score = 92.8 bits (229), Expect = 1e-15
Identities = 132/673 (19%), Positives = 297/673 (44%), Gaps = 31/673 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENK-------VGDFEAAIATLNDELLNE----KDDKKCIVNDR-N 2151
++N R++LE ++ + +K + +F+A ++ ++ L + K+D+K + + N
Sbjct: 9647 LMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 9706
Query: 2150 IVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN 1971
++E +A ++ + N+E E+++ + IVE +++ L S E + ++
Sbjct: 9707 VIEMKTKAEPEEIKKEKEKE---NEEEEEEEEEIRVIVETERKELYQIKSELERVRSEID 9763
Query: 1970 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE-----LERKKDDNNAI 1806
E D K I ++ LE K + + +E ++ L+++ LE+ + +
Sbjct: 9764 HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKE 9823
Query: 1805 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1626
I + L + + + D + +E D+ E N+L+ ++
Sbjct: 9824 IVEKLMVEVEEQRKDIQLQKEELDIERQKIAD-----------------EQNLLVQNKAK 9866
Query: 1625 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS---RSLKEHFLREEEDEVLERSASN 1455
+ ++++ + + + E + T+ E+ HL+ + RS+ E R +ED LE+ +++
Sbjct: 9867 LQNENERIKKVDEEIKKE--RETLREMEIHLKKEKEELRSIIEETQRRKED--LEKMSTD 9922
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR 1275
+ K L+ ++D L+E E E+ E T L++R D + E+L
Sbjct: 9923 INEQKL----HLKNQRD----LLEQ----EREEINHEMTQLQQRIDEFDAQVSKQREDLT 9970
Query: 1274 KEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCS 1095
K+++ E E++ E+T + + + +L +M EK+ ++
Sbjct: 9971 KQEM------------EEERKSLEETKARI------IEMKTKAELQEIMQEKEEEDEE-- 10010
Query: 1094 DLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLE 915
E + + +E ++ + E K S + H E K DDK+ I + + ++ + +
Sbjct: 10011 --EMRVIVEMEREELNQIKSELKRVRSEIDH--EQKKLNDDKKIIEQEKEDLEKMKSEIM 10066
Query: 914 SKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 735
++ ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 10067 TQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQ 10126
Query: 734 KDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
K D N+A+ Q +RI E++E I K K+ LK++ L + E + +
Sbjct: 10127 KIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSVIE 10182
Query: 572 ES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFS 399
E+ ++K+DLEK ++ +K + + RD L +E + W + + F
Sbjct: 10183 ETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDEFD 10235
Query: 398 RKTSPL---DITK 369
+ S D+TK
Sbjct: 10236 AQVSKQKEEDLTK 10248
Score = 92.8 bits (229), Expect = 1e-15
Identities = 128/675 (18%), Positives = 276/675 (40%), Gaps = 35/675 (5%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N R++LE ++ + +++ + I + ++ +++D + + + E K E K
Sbjct: 9932 NQRDLLEQEREEINHEMTQLQQRIDEFDAQVSKQRED----LTKQEMEEERKSLEETKAR 9987
Query: 2108 DFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEKDD 1944
E E++ EK+++ + IVE +++ L S + + ++ E DD
Sbjct: 9988 IIEMKTKAELQEIMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDD 10047
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDKRI 1779
KK I ++ LE K + + +E ++ L++ +LER +N+ I + L ++
Sbjct: 10048 KKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKV 10107
Query: 1778 SDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTA 1599
+ + D + +E D+ E QK D++
Sbjct: 10108 EEQRKDIRLQKEELDI---------------------------------ERQKIADEQGL 10134
Query: 1598 LIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
++++ + + E+ ++ + +LKE E L
Sbjct: 10135 VVQNKAKLQNENERIKEMDEEIKKEKETLKE------------------------MEAHL 10170
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---DAIHEE-----------E 1281
RKEK+ +++E E +K+ LEK + N D M D + +E +
Sbjct: 10171 RKEKEEMRSVIE--ETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQ 10228
Query: 1280 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1101
R ++ D + E +K+ E+ E I + + + +++ EK+ E+
Sbjct: 10229 QRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEE- 10287
Query: 1100 CSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV 921
E A + +E + +I+ +LE + E K DDK+ I + + ++ +
Sbjct: 10288 ----EVMRAKVEMKKEELD-QIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSE 10342
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
+ + ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 10343 IMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIE 10402
Query: 740 TGKDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 579
K D N+A+ Q +RI E++E I K K+ LK++ L + E +
Sbjct: 10403 RQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSV 10458
Query: 578 NKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQG 405
+E+ ++K+DLEK ++ +K + + RD L +E + W + +
Sbjct: 10459 IEETQRRQKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDE 10511
Query: 404 FSRKTSPL---DITK 369
F + S D+TK
Sbjct: 10512 FDAQVSKQKEEDLTK 10526
Score = 91.7 bits (226), Expect = 3e-15
Identities = 140/737 (18%), Positives = 310/737 (42%), Gaps = 97/737 (13%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ +V+++ +L + L+NK + D+ +++ +
Sbjct: 8997 ERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEE 9056
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N + K+ K + +R + + ++ +F+A + +E
Sbjct: 9057 TSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEE 9116
Query: 2072 -LLNEK---DDKKCIVEADKQALESK---------VSVFEAAIATLNDELLNEKDDKKCI 1932
L N+K +++KC+ E + + +E K ++ + TL ++++ EK+ + +
Sbjct: 9117 DLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAM 9176
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADA 1758
L+ ++ L+ ++L KT ++ E ++ DD I K+ L+K S++
Sbjct: 9177 TIK---LKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 9233
Query: 1757 PQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD------KTA 1599
+ ++E +++ I +IV L + E+Q +K++ K A
Sbjct: 9234 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIA 9293
Query: 1598 LIKDLVAAEPGK--------RTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIM 1443
+DL+ + R +NE++ + ++ H +E+E+ M
Sbjct: 9294 DEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEKEE------------M 9341
Query: 1442 KAIREEELRKEKDGKSA----------LVENGEGCEAEKQGL--EKTVLERRASNLDTM- 1302
K+I EE R+++D + L++ + E EK+ + E T L++R D
Sbjct: 9342 KSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQV 9401
Query: 1301 ------DAIHEEELRKEKVD----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
D ++E+++E+ K+ + E E E EK + E + +
Sbjct: 9402 SKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 9461
Query: 1151 QRDLDRVMAE-------------------------KQALEKRCSDLEAKNASLTDNQEGH 1047
++LDR+ +E KQ LEK S++ + + + +
Sbjct: 9462 GKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSEL 9521
Query: 1046 EAEIERK-LEASNLTHNDELHKE-----KDDKESIMNDLDHVKAERQVLESKVSDMETTY 885
E +I++ +E ++ ++ E+ ++ ++ K I + + ERQ + + +
Sbjct: 9522 ENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 9581
Query: 884 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------D 723
S L NE ++ + NE ER+ L+ ++ LEK+ ++++ E + K+D D
Sbjct: 9582 SELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSE--ETRRLKEDLEKMSTD 9639
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQD-- 552
N+ K + +R LE+ + K K+L + I+ + ++V++ +E DL KE K+D
Sbjct: 9640 VNKQNKDLMNQR-DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRK 9698
Query: 551 ----LEKRVLELTSKLE 513
+ V+E+ +K E
Sbjct: 9699 SLEETKANVIEMKTKAE 9715
Score = 91.3 bits (225), Expect = 4e-15
Identities = 146/692 (21%), Positives = 284/692 (41%), Gaps = 60/692 (8%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQAL---ENK 2241
+R LE LE K + + I +NILE K L + +
Sbjct: 12300 ERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQ 12359
Query: 2240 VGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNE 2061
V + + T+ + +E ++ +C+ RN +E +K+++ ++++ + I L E+ +E
Sbjct: 12360 VQQQKHEMETIRKTMKSEMENLECL---RNELEDEKKSMLSRLSMEKHEIDKLKTEIQSE 12416
Query: 2060 KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYK 1881
K+ +E +K+ L+ E+ L++ + DK I +++ LE K L+ K
Sbjct: 12417 KES----IEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRK 12472
Query: 1880 VADLE-----AAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIX 1716
L+ A + T + K D++ ++ L +D++ A + E D+ L
Sbjct: 12473 AEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQA--KILESDVQLLQT 12530
Query: 1715 XXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNE 1548
+ +LE N L L +EL+KEK +I D+ + +
Sbjct: 12531 EKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------D 12582
Query: 1547 IVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGE 1374
V+ L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 12583 AVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENM 12641
Query: 1373 GCEAEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTE 1242
+ + ++ + E R D + DA+ + +EL K D E
Sbjct: 12642 KMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKE 12701
Query: 1241 NGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA---- 1083
+ E E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 12702 HVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADD 12761
Query: 1082 --------KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH 942
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 12762 IKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQ 12821
Query: 941 ---------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGL 792
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +
Sbjct: 12822 KEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 12881
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 612
E +EKQ++++ +EL K+L +++ +
Sbjct: 12882 E-------------------------SEKQSIERERAEL-----------KRLKEEVEVQ 12905
Query: 611 LSEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
E T LQ+D N KEK+ LE T ++
Sbjct: 12906 -HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 12936
Score = 90.1 bits (222), Expect = 8e-15
Identities = 141/644 (21%), Positives = 275/644 (42%), Gaps = 49/644 (7%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN- 2118
I NDR E L+N+ D E + + DE N + K+ + +DR+ +E ++ LE
Sbjct: 2638 IDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKT 2697
Query: 2117 --KVADFEATIATLND-------ELLNEKD---DKKCIVEADKQALESKVSVFEAAIATL 1974
++ D E + + + E+ E++ K + K+ LE + FE A +
Sbjct: 2698 KTEMKDLEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1973 N-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERK--KDDNNAI- 1806
+ E L E+ +K+ I D+ + ++ E + L K N+EL+++ +D+ + I
Sbjct: 2758 SLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE 2815
Query: 1805 -IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1638
IK L K D + ++D E+D ++ + + E N+ +L
Sbjct: 2816 QIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVL 2873
Query: 1637 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSA 1461
+ L+ ++D L K+ + + ++ LES++R + ++E E+LE+
Sbjct: 2874 KQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1460 SNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1290
L+ K E+E KEK S E E ++E++G+ KT R MD
Sbjct: 2931 LTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIKKEMD--- 2981
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL 1110
EL++ +++ EN E +KQ ++ + D++ K L
Sbjct: 2982 --ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKIEQIKAEL 3018
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDKESIMNDL 948
+K D E + + ++ +E + ++ +E S DE + K+ + +D
Sbjct: 3019 QKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDR 3078
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
D ++ ER LE ++M L ++++Q ER+ LE +K L K+ DLE
Sbjct: 3079 DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLE 3138
Query: 767 ATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL------TDKAK 639
E + +D ++E++ +K+ + ELE+ L + K
Sbjct: 3139 KERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQK 3198
Query: 638 KLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 510
K+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3199 KIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 89.7 bits (221), Expect = 1e-14
Identities = 137/679 (20%), Positives = 294/679 (43%), Gaps = 19/679 (2%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
IVN L + LE +A I DE+ + ++K I+N++ +E K ++
Sbjct: 3342 IVNKTEQLRLREVELEQ----LQALIYRQQDEI---EANRKAIINEKYRLEGQKTEIDRL 3394
Query: 2114 VADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKC 1935
+ + + + N + +K ++ A K ++ +++ E + ++LN + K
Sbjct: 3395 QREVNQMMEYASKDRANLEKEKSEMI-AQKHQMDIELNK-ERGLIEERTQMLNTYE--KE 3450
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISDLKA 1764
+ R LE + L+Y ++ K L EL+R+ DD + +K ++R S K
Sbjct: 3451 MDQKRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKM 3510
Query: 1763 DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE----ELQKEKDDKTAL 1596
++DD+ L + + +LHE ++QKEK + +
Sbjct: 3511 AENLEKEKDDLAHLAED--------------TKRKDDEMKVLHESALADIQKEKCNLEQM 3556
Query: 1595 IKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE-- 1422
+ + NE++ E K L+E L++ + E+ R + + K+I E E
Sbjct: 3557 RESMFKQ-------NEMIDS-EKKKMILREDKLQQMQAEI-NRQQTEMDTKKSIIENERA 3607
Query: 1421 --LRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
+K +D + L + E E + + + EK +LE L +++L + D
Sbjct: 3608 AMTKKNQDLMTELTKQSEDVEIQMKEVLTEKELLESDRKLLKKDVENLQQKLLIIESDSE 3667
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLE---PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEA 1083
+L ++ E E EK+ ++ DL+ I + Q + RV ++K L+
Sbjct: 3668 SLKQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQK 3727
Query: 1082 KNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
N ++T +E H+ + + K DEL + K + +++ +L+ E++++ S
Sbjct: 3728 MNDNIT--REIHDIKYQEKQMKQK---QDELDQLKTEIQNLQQELEK---EKEIIMKDRS 3779
Query: 902 DMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM-KTGKDD 726
+++ S L+ + D E NER L+ K+ +E++ ++E HD + + D+
Sbjct: 3780 ELDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDE 3839
Query: 725 DYN--EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 552
D + +KQ ++ ++LE+ + I ++ ++ I + + E + +E K +++
Sbjct: 3840 DLKMMKLQKQVFEEEKNKLEQ-MKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKE 3898
Query: 551 LEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDIT 372
+ E T K ++ + D + E+ M++ + FE++ + S++T D+
Sbjct: 3899 SFTHLAEDTKKEQEIL----DEIKVANESLMAELQKEKS--NFEEMRENISKQTE--DVE 3950
Query: 371 KTCDAVDISEDSTTNIQVD 315
+ + + ED +Q +
Sbjct: 3951 NKKENLRLREDELRQLQAE 3969
Score = 89.0 bits (219), Expect = 2e-14
Identities = 139/671 (20%), Positives = 284/671 (42%), Gaps = 55/671 (8%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R I+E ++ L + + + ++ E DDKK I ++ +E K + +
Sbjct: 10013 RVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQM 10072
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALES---KVSVFEAAIATLNDELLNEK----DD 1944
E + L D + + D ++ +E K+ ++ KV I +EL E+ D+
Sbjct: 10073 EEERSEL-DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADE 10131
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISD 1773
+ +V ++ L+ + ++ +++ K TL + L ++K++ ++I++ ++ D
Sbjct: 10132 QGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKED 10191
Query: 1772 LK---ADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
L+ D +++Q+ L+ + L+ I ++ K+K++
Sbjct: 10192 LEKMSTDVNKQNQD-----LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED- 10245
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE---EEDEV-----------LERS 1464
L K E K + +E K+++ E +E EE+EV L++
Sbjct: 10246 -LTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQI 10304
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIH 1290
S L +++ + E +K D K + + E E K + ++ +E S LD + I
Sbjct: 10305 KSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELD--NKIK 10362
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDLEPT--------IPSLNDALQR 1146
+ +L + ++ S E E+Q + K LD+E + LQ
Sbjct: 10363 QTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQN 10422
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ +R+ + ++K L+ A L +E E+ +E + ++L K D
Sbjct: 10423 ENERIKEMDEEIKKEKETLKEMEAHLRKEKE----EMRSVIEETQRRQKEDLEKMSTDVN 10478
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
+ +MN D +K ER+ + K + +LQQ++D+ +A ++++ + KQ
Sbjct: 10479 KQNQDLMNQRDLLKQEREEINHKWT-----------QLQQRIDEFDAQVSKQKEEDLTKQ 10527
Query: 797 G-LEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD 624
+E+ LE T I IEMKT + + + EK+ E EE + + K+ L
Sbjct: 10528 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE------KEEEEVMRAKVEMKKEELDQ 10581
Query: 623 INIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I L SE+ Q+ LN + K EK+DLEK E+ + ++ + + I++
Sbjct: 10582 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 10641
Query: 467 AWMSDCMVPDN 435
++ C + ++
Sbjct: 10642 TYIEKCDIENS 10652
Score = 88.2 bits (217), Expect = 3e-14
Identities = 131/622 (21%), Positives = 266/622 (42%), Gaps = 27/622 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVG-------DFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD 2136
I+ R +E + L+NK+ D E + + ++ ++ +K I + ++ +
Sbjct: 9790 IMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIE 9849
Query: 2135 KQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLN 1956
+Q K+AD + + +L NE + K + E K+ E+ + + L
Sbjct: 9850 RQ----KIADEQNLLVQNKAKLQNENERIKKVDEEIKKERET--------LREMEIHLKK 9897
Query: 1955 EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDK 1785
EK++ + I+ + + K+ LE D+ K L ++ LE+++++ N + + L +
Sbjct: 9898 EKEELRSIIEET---QRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQ-LQQ 9953
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
RI + DA Q +D+ I + + + +E ++E +++
Sbjct: 9954 RIDEF--DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEE 10011
Query: 1604 TALIKDLVAAEPG--KRTVNEIVSHLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAI 1434
+I ++ E K + + S ++ + + L + + E+E E LE+ S + +
Sbjct: 10012 MRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQ 10071
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
EEE R E D K +++T LER +++ I ++ + K + +
Sbjct: 10072 MEEE-RSELDNK----------------IKQTDLERH--DIENSKEIVQKLMVKVEEQRK 10112
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 1074
+ E + E+Q + D + + LQ + +R+ + ++K L+ A
Sbjct: 10113 DIRLQKEELDIERQ----KIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEA 10168
Query: 1073 SLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KESIMNDLDHVKAERQVLESKV 906
L +E E+ +E + ++L K D + +MN D +K ER+ + K
Sbjct: 10169 HLRKEKE----EMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKW 10224
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG-LEKRVLDLEAT-IHDIEMKTGK 732
+ +LQQ++D+ +A ++++ + KQ +E+ LE T I IEMKT
Sbjct: 10225 T-----------QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKT 10273
Query: 731 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKESK 564
+ + + EK+ E EE + + K+ L I L SE+ Q+ LN + K
Sbjct: 10274 EPEKIKKEKE------KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKK 10327
Query: 563 ----EKQDLEKRVLELTSKLEK 510
EK+DLEK E+ + ++
Sbjct: 10328 MIEQEKEDLEKMKSEIMKQRQQ 10349
Score = 87.8 bits (216), Expect = 4e-14
Identities = 143/649 (22%), Positives = 278/649 (42%), Gaps = 45/649 (6%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEA---AIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N+++ ++ E K + + A+ +N EL + + K + + EAD Q +NK
Sbjct: 12281 NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTE 12340
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
+ + + EL EK V+ K +E+ ++ + L + L NE +D+K +
Sbjct: 12341 ELKNILEREKSELYQEKAQ----VQQQKHEMETIRKTMKSEMENL-ECLRNELEDEKKSM 12395
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDKRISDLKADA 1758
R L K ++ ++++ K ++ +E L++ KD+N + + LD I + D
Sbjct: 12396 LSR--LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENES-KRTQLDNTIEKMNMDK 12452
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
+E D +I ++L+ L EE++K + + +D
Sbjct: 12453 LSIQREKD----------------SLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKI 12496
Query: 1577 AEPGKRTVNEIVS---HLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ + E+ S +E +++ L+ L + E E+LE+S + +++ E+L K+
Sbjct: 12497 LDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLR----EDLEKQ 12552
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ ++ EK LE+ + + D + ++ E K+ K+ TE E
Sbjct: 12553 RKRNDLTLQE---LRKEKMALEQMITD-ITKEKDAVASLQNEVSLKQHELKNKETELDE- 12607
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+++ + + LE S N Q+++D + E K +DLE+ L + +
Sbjct: 12608 ---QRKEMDDLRMQLEMRQNSTNKQ-QQEVDVFIVENM---KMRNDLESMKTLLDEERRQ 12660
Query: 1049 HEAEIERKLEASNLTH---------NDELHKEKDDKESIMNDLDHVKAERQ---VLESKV 906
+ I+ + N+ H DEL K D I + +HV+ ER+ VL ++
Sbjct: 12661 LQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD---IKTEKEHVEKEREEIDVLNKEI 12717
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE--MKTGK 732
+ +LN E+ E F E G A + LE+ DL A DI+ ++T K
Sbjct: 12718 IKSKEELQSLNLEI-------EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEK 12770
Query: 731 DDDYNEAEKQT-------LKKRISELEEAIS-------------ILTDKAKKLLKDI-NI 615
+ EK+T L+K+ +ELEE + I+ DK +K ++DI +
Sbjct: 12771 QMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTV 12830
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
SE L+++ ++ +K L ++V +LE+ + RD + K+
Sbjct: 12831 IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKK 12879
Score = 87.4 bits (215), Expect = 5e-14
Identities = 127/646 (19%), Positives = 279/646 (43%), Gaps = 58/646 (8%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
++ KQ ++ K A+ L K+ ++ I ++ +E +K ++ + +
Sbjct: 8633 IQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKV 8692
Query: 2093 IATLNDELLNEKDDKKCIVEAD----KQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
+ E + + +K I EAD K+ E+ E + +++ N ++ K +
Sbjct: 8693 L-----EEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQ 8747
Query: 1925 DRNILEAAKQALEYKVADL-----------EAAKTTLNDELERKKDDNNAIIKKA--LDK 1785
+R ++ KQ L+ + DL E +K +L++E + + N I+++ L+K
Sbjct: 8748 ERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEK 8807
Query: 1784 RISDL-----KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE--- 1629
D+ K D Q + +++ A+ K LE ++ ++EE
Sbjct: 8808 EKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGD 8867
Query: 1628 ---LQKEKDDKTALIKDL-VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE-VLERS 1464
++ + + + I+++ V A+ ++ +++I S LE + + + D ++E+
Sbjct: 8868 LEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKE 8927
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDTMD--- 1299
++L MK+ + ++ +D +S L + + EK +EK ++ER + ++
Sbjct: 8928 RNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDF 8987
Query: 1298 AIHEEELRKEK---VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-------Q 1149
+ +EEL E+ VD+ L CE E Q + + ++E + + + L Q
Sbjct: 8988 KLKKEELALERQNIVDEKYLLAQ---CETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 9044
Query: 1148 RD-------LDRVMAEKQALEKRCSDLEAKNASLT---DNQEGHEAEIERKLEASNLTHN 999
RD ++ +K+ LEK + + + L D E EI K +
Sbjct: 9045 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 9104
Query: 998 DELHKEKDDKESIMNDLDHVKAERQVLES---KVSDMETTYSTLNNELQQKMDDNEAFLN 828
+ + + KE + + ++ ER+ LE K+ +M+T ++E+ QK+++
Sbjct: 9105 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEE------ 9158
Query: 827 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 648
L+ +++ + K EA ++M E++ L + SEL + +
Sbjct: 9159 ----LQTLQEQIMKEKEKAEAMTIKLKM-----------EREDLDQIKSELVREKTEVDH 9203
Query: 647 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
+ KKL DI + E +L++ ++ +KQ++EK EL +K+++
Sbjct: 9204 EQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 9249
Score = 85.5 bits (210), Expect = 2e-13
Identities = 144/713 (20%), Positives = 299/713 (41%), Gaps = 118/713 (16%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
++N R++L+ ++ + +K + I + ++ +K++ + + + E K E K
Sbjct: 10206 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED--LTKQKKMEEERKSLEETK 10263
Query: 2114 VADFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEK 1950
+ E T +++ EK+ + + VE K+ L+ S E + ++ E
Sbjct: 10264 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 10323
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDK 1785
DDKK I ++ LE K + + +E ++ L++ +LER +N+ I + L
Sbjct: 10324 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMV 10383
Query: 1784 RISDLKADAPQRDQE---------DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
+ + + D + +E D+ ++ ++ ++ L E
Sbjct: 10384 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKE 10443
Query: 1631 ---ELQKEKDDKTALIK----------------------DLVAAEPGKRTVNEIVSHL-- 1533
L+KEK++ ++I+ DL+ + E ++H
Sbjct: 10444 MEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWT 10503
Query: 1532 --------------ESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGK 1398
+ K L + EEE + LE + + MK E E+++KEK+ +
Sbjct: 10504 QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE 10563
Query: 1397 SALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEE--------LRKEKVD---- 1260
V + E +K+ L+ K+ LER S +D HE++ + +EK D
Sbjct: 10564 EEEVMRAK-VEMKKEELDQIKSQLERVRSEID-----HEQKKLNDDKKMIEQEKEDLEKM 10617
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDL---EPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
KS + + + E E+ E + + I + + +Q+ + V +K ++ + +L
Sbjct: 10618 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 10677
Query: 1088 EAKNASLTDNQE---GHEAEIER------------KLEASNLTHNDE-LHKEKDDKESIM 957
+ + + D Q+ +++E++ K E L + L KEK++ +SI
Sbjct: 10678 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 10737
Query: 956 N-------DLD----HVKAERQVLESKVSDMETTYSTLNN---ELQQKMDDNEAFLNER- 822
DL+ H+ ++Q L S+ +E +N+ +LQQ++D+ +A ++++
Sbjct: 10738 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 10797
Query: 821 -DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDK 645
+ L K+ E R E + +EMKT + + + EK+ E E+ + + +
Sbjct: 10798 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEK-----EEEEQEMRVKVEM 10852
Query: 644 AKKLLKDINIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEK 510
+K ++ I L SE+ Q+ LN + K EK+DLEK E+ + ++
Sbjct: 10853 ERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQ 10905
Score = 85.1 bits (209), Expect = 3e-13
Identities = 128/613 (20%), Positives = 259/613 (42%), Gaps = 34/613 (5%)
Frame = -2
Query: 2261 KQALENKVGD-FEAAIATLNDELLNEKDDKKCIVN-DRNIVEADKQALENKVADFEATIA 2088
KQ + K+ D + + + D + + K ++ +++ +E K ++ ++ +FE +
Sbjct: 13384 KQPIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNME 13443
Query: 2087 -TLND---------ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
TL + +LL++KDD ++ + +E+ F+ IA L + K DK+
Sbjct: 13444 ETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE 13503
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAA------------KTTLNDELERKKDDNNAIIKKA 1794
I N+ L+ +Q E + + + KT L D E+KK D ++ +K
Sbjct: 13504 NIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLK-- 13561
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
++D AD+ + D E + L + V L EEL E
Sbjct: 13562 ----LTD--ADSAKTDGEREAQTL-----------ETKVQDVLQLTDYTTQDQEELHDEM 13604
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAI 1434
++K +I +L A+ + + L+ + RS +E + E LER ++L
Sbjct: 13605 ENKMKIILELNEAK-------KDLQKLKEECRSAEEE--KSVIMESLERRRNSL------ 13649
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLERRASNLDTMDAIHEEELRKEKVDK 1257
E+++ E + +++ + E Q +E K ++ R+ + ++ ++
Sbjct: 13650 --EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQGQEATETT 13707
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPS----LNDALQRDLDRVMAEKQALEKRCSDL 1089
+T+ E + K+ + TV LE T+ S + D+L ++++ V K ++ L
Sbjct: 13708 GHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQL 13767
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD----HVKAERQV 921
E + + E E +E +E + + ++L + DKE + N LD ++ +
Sbjct: 13768 EQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKLLQLTHDKEDLSNTLDKKNKEIENNTET 13826
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
K++ +ETT + + K+ +E +L L+ T + E++
Sbjct: 13827 SLKKIAQLETTIVLMKKD---------------------KENIENELLQLKQTEQEREIQ 13865
Query: 740 TGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 564
G DD NE EK K +ELE+ + KK +D ++ L++ + D +E++
Sbjct: 13866 RGTDDTSNEREKYDEKVTYKTELED-----NKEKKKPDRDSSLKLTDADSAKTDGEREAQ 13920
Query: 563 EKQDLEKRVLELT 525
+ + VL+LT
Sbjct: 13921 TLETKVQDVLQLT 13933
Score = 84.0 bits (206), Expect = 6e-13
Identities = 125/589 (21%), Positives = 252/589 (42%), Gaps = 18/589 (3%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDEL-LNEKDDKKCIVNDRNIVEADKQALENKVADFE- 2100
+E KQ ++N+ + A L +E NE+ +++ + N + A + + DFE
Sbjct: 5874 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQKVN-QQKQATAFQMEKTDFER 5932
Query: 2099 --ATIATLNDELLNEKD-DKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
I N EL ++++ +KK I E K+ TL + N + I
Sbjct: 5933 IKTEIDQANKELADQQEKNKKTITEMQKER------------ETLEEMRANISKQVETIT 5980
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA-LDKRISDLKADAPQ 1752
N+ L + + L D+ L + E + N +++ LD+R SD+ D Q
Sbjct: 5981 NENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQ 6032
Query: 1751 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAE 1572
++ +D M+ ++N+E L + + + K D +L + A E
Sbjct: 6033 KEVDDLMD--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACE 6078
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
+ +NE +E + L ++ ++D++ ++R NL + K + E ++ + K
Sbjct: 6079 QLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKI 6138
Query: 1394 ALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGE 1233
+L G + +EK E+ ++E A+ LD + E + +E++D++
Sbjct: 6139 SLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKT 6198
Query: 1232 GCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE 1053
+ EKT DL+ T +N D + + ++ L K
Sbjct: 6199 YYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK----------------- 6235
Query: 1052 GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 873
E E +++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + +
Sbjct: 6236 --EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMM 6290
Query: 872 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ--- 702
E + D E NE+D L+ ++ ++K + +L+ E + + N+ +Q
Sbjct: 6291 KEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTE 6344
Query: 701 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 561
+K + L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 6345 EIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 6393
Score = 84.0 bits (206), Expect = 6e-13
Identities = 115/623 (18%), Positives = 262/623 (42%), Gaps = 6/623 (0%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
+ L E+ ++ K ++++ I +++ Q L + + L E+ N K DK +
Sbjct: 7532 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNL 7591
Query: 2039 VEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA 1860
E K LE K E+ L E + KK I ++ +E +++ +E ++ + E
Sbjct: 7592 -EKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVK 7650
Query: 1859 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 1680
T ++++ K++ + ++ L K+ + + D + M L
Sbjct: 7651 GFT---DVQKYKEELQIVTEELLTKKRN---LEQLNSDVQHLMQTLEEVDIQYIKKKAEL 7704
Query: 1679 XKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF 1500
I S ++ IL E+ +K+ ++ +I+++ + ++N + KE+
Sbjct: 7705 EHITSEIQKREQIL-EKQKKKLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENL 7763
Query: 1499 LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRA 1320
RE+++ L R EL++++D VE+ ++ K ++ +
Sbjct: 7764 RREKQETELFRG-------------ELQRQRDE----VESSRQALIMEKDQFKLKIDHQR 7806
Query: 1319 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1140
+ + A +E R E ++ + + E+ + +E + + + L ++
Sbjct: 7807 NEMSA--AFEKEHKRLENMENDLENQRAKLAESLNDAAK-----MEQKLQQMKNELNKEK 7859
Query: 1139 DRVMAEKQALEKRCSDLEAKNASLTDN----QEGHEAEIERKLEASNLTHNDELHKEKDD 972
++V KQ ++ +E + + ++GHE ++++K E + D+L ++ +
Sbjct: 7860 EQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANS 7913
Query: 971 KESIMNDLD-HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG 795
+ + DL ++ +RQ +E ++MET +L+ ++ DD N+RD E
Sbjct: 7914 ESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTH 7973
Query: 794 LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 615
LE + +L D+E K + + +E K+ ++ + LE + K + K++
Sbjct: 7974 LELKREELVRETEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMEN 8033
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPD 438
SE +L ++ +LE RV +E L++ + + E MS+ + +
Sbjct: 8034 VHSERQKLLLLQGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTE 8091
Query: 437 NWVPFEDLVQGFSRKTSPLDITK 369
+ L++ R+ L+I+K
Sbjct: 8092 Q-NEYRKLIEELQREKEQLEISK 8113
Score = 84.0 bits (206), Expect = 6e-13
Identities = 140/656 (21%), Positives = 289/656 (44%), Gaps = 72/656 (10%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
IA + D+LL EK+D + N + + +++++ D + + N +LL K +
Sbjct: 12135 IADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTE---- 12190
Query: 2039 VEADKQALESKVSVFEAAIATLNDELL---NEKDDKKCIVNDRNILEA-AKQALEYKVAD 1872
++ ALE + + +N ++ E++ + ++ + E A+ ++ + D
Sbjct: 12191 IQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 12250
Query: 1871 LEAAKTTL----------NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMN 1728
+E+ K L N EL+ + ++ +IKK ++ + K + QR+++ + MN
Sbjct: 12251 IESVKVRLVTESNQIDKMNSELKTRSEELENLIKK--QQKEFETKENEMQRERKALEKMN 12308
Query: 1727 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG-----K 1563
A + + N + + +LQKEK +KT +K+++ E K
Sbjct: 12309 AELERKSTE----------LKNKIEKVTVWEADLQKEK-NKTEELKNILEREKSELYQEK 12357
Query: 1562 RTVNEIVSHLESKSRSLKEHF-----LREEEDEVLERSASNLAIMK-------------- 1440
V + +E+ +++K LR E ++ + S L++ K
Sbjct: 12358 AQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQSEK 12417
Query: 1439 -AIREE-----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA------ 1296
+I EE +L+ E + K ++N EK ++K ++R +L+ + A
Sbjct: 12418 ESIEEEKKTLKQLKDENESKRTQLDN----TIEKMNMDKLSIQREKDSLEEIKADLQRKA 12473
Query: 1295 -IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1119
+EE+RK S ++++ + + +++ E+ + + I L+ D+ + EK
Sbjct: 12474 EKLDEEMRKAVQITSQISQDAKILDDDRE-KEEELRSMRADIERQAKILESDVQLLQTEK 12532
Query: 1118 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
+ LEK S T+N E ++E++ + ++LT EL KEK E ++ D+
Sbjct: 12533 EILEK----------SKTENDLLRE-DLEKQRKRNDLT-LQELRKEKMALEQMITDITKE 12580
Query: 938 KAERQVLESKVSDMETTYSTLNNEL---QQKMDDNEAFLNER-DGLEAVKQGLEKRVLDL 771
K L+++VS + EL +++MDD L R + +Q ++ +++
Sbjct: 12581 KDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVEN 12640
Query: 770 EATIHDIE-MKTGKDDDYNEAEKQTLKKRISELEEAISIL----------TDKAKKLLKD 624
+D+E MKT D+ E++ L+ I E+ ++L TD+ +K D
Sbjct: 12641 MKMRNDLESMKTLLDE-----ERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 12695
Query: 623 INIWLSEVTELQED---LNKE-SKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I V + +E+ LNKE K K++L+ LE+ ++ I G R + ++++
Sbjct: 12696 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEI-EMFKQEIAGKRAQIESLEQ 12750
Score = 83.6 bits (205), Expect = 8e-13
Identities = 137/630 (21%), Positives = 251/630 (39%), Gaps = 35/630 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN 2118
++V + E KQ +E++ E A L E + + ++ I NDR E L+N
Sbjct: 2792 NVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQN 2851
Query: 2117 KVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ D E + + DE N + KQ LES E L KD +K
Sbjct: 2852 EKKDIETSTDRIRDEEAN--------LRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEK 2903
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+ + E ++ + LE K TL+ + E + + + K+ D IS +
Sbjct: 2904 QLESQNRQHEIQLAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKAD--ISLREELQ 2961
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNIL---ILHEELQKEKDDKTALIKD 1587
Q ++E + +V LE N L I+ +E K + K L K+
Sbjct: 2962 EQSEREGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKE 3021
Query: 1586 LVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSASNLAIMKAIREEELRKE 1410
E +R + E R+ +E ++ + E + +E S IR+EE E
Sbjct: 3022 AEDTEKQRRDI-------EKDRRNNEEMVIKLQNEKKDIETSTDR------IRDEEANLE 3068
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSA------- 1251
K L + + E E+ LEKT E I + E++ ++ K
Sbjct: 3069 VQ-KQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLK 3127
Query: 1250 --LTENGEGCEAEKQGPEKTVLDLEPT-----------IPSLNDALQRDLDRVMAEKQAL 1110
L++ E E E+ EK D+ + I + +++++D + +Q L
Sbjct: 3128 INLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNL 3187
Query: 1109 EKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
K + E + + D ++ E AE++++ E + L EL E+ + E L
Sbjct: 3188 AKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKL----ELQNERQNLEEAGTKL--- 3240
Query: 938 KAERQVLESKVSDMETTYSTLNN-----ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 774
K +R+ +ES ++ L N E+Q+K +++ + ER +E L+K V D
Sbjct: 3241 KKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTD 3295
Query: 773 LEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 603
+ D+E + ++ + N +AE Q K + L++ IS + + + E
Sbjct: 3296 IAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVE 3355
Query: 602 VTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ +LQ + ++ E + K ++ +LE
Sbjct: 3356 LEQLQALIYRQQDEIEANRKAIINEKYRLE 3385
Score = 79.7 bits (195), Expect = 1e-11
Identities = 110/587 (18%), Positives = 242/587 (41%), Gaps = 7/587 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
RN +EA K +EN+ + + D + K ++ + +++ + L KV
Sbjct: 12800 RNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQRE 12859
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + L ++ ++ ++ K I+E++KQ++E + A + L +E + + ++ + D
Sbjct: 12860 QEELERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEE-VEVQHERTLLQQD 12914
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR-- 1749
+N+++ K+ LE + A L +E++RK + + + K+ KR + P+
Sbjct: 12915 KNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIE 12974
Query: 1748 -----DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+EDD+ ++ + +E+ K + + +++
Sbjct: 12975 IEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEET 13034
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
VA + V ++ L S+ + +++H L LA MK I + E + K
Sbjct: 13035 VATTAKQPIVIKLEDTLTSEVQEMRDH---------LNNEIKELARMKTIMKMEKDQLKQ 13085
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE 1224
KS + E E + +E+ + E+ + + H++E +DK + E
Sbjct: 13086 AKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDK-----KNKEIE 13137
Query: 1223 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE 1044
+ K + LE TI + + + ++ KQ ++R +++ K A +T
Sbjct: 13138 NNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQER--EIQRK-ADVTST----- 13189
Query: 1043 AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL 864
E+++ +T+ EL +D KE I D D E +S +D E TL ++
Sbjct: 13190 ---EKEMYTEKVTYKTEL---EDSKEKIKPDRDST-LELTDTDSAKTDGEREAQTLETKV 13242
Query: 863 QQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI 684
Q + + +++ L + K +L+L D+ Q LK+
Sbjct: 13243 QDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDL---------------QKLKEEC 13287
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 543
EE S++ + ++ + SEV L ++++ ++ K ++++
Sbjct: 13288 RSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQ 13334
Score = 79.0 bits (193), Expect = 2e-11
Identities = 119/619 (19%), Positives = 262/619 (42%), Gaps = 35/619 (5%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
++R ++ + ++ ++ + E L E N + KK I ++R+ +E K L+ +
Sbjct: 3161 SEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEA- 3219
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
E T L +E N ++ ++ D++ +ES L + + + +K
Sbjct: 3220 --EKTKLELQNERQN-LEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANE 3276
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA-------------IIKKALD 1788
+++ + E L+ V D+ AK L ++L +++ N ++K+ +
Sbjct: 3277 SNKQMQERVLIELKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGIS 3336
Query: 1787 KRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD 1611
++ D+ Q R +E ++ L K + N + + E+ + +
Sbjct: 3337 EQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQR 3396
Query: 1610 DKTALI----KDLVAAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAI 1446
+ ++ KD E K +E+++ L KE L EE ++L +
Sbjct: 3397 EVNQMMEYASKDRANLEKEK---SEMIAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQ 3453
Query: 1445 MKAIREEELRKEKDGKSALVENGEGCEAEKQGLE------KTVLERRASNLDTMDAIHEE 1284
+ E E+++ K K A+ E + K L+ K + E+ + +++ + E
Sbjct: 3454 KRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKM-AE 3512
Query: 1283 ELRKEKVDKSALTENGEGCEAE-KQGPEKTVLDLEP---TIPSLNDALQRDLDRVMAEKQ 1116
L KEK D + L E+ + + E K E + D++ + + +++ + + + +EK+
Sbjct: 3513 NLEKEKDDLAHLAEDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKK 3572
Query: 1115 ALEKRCSDLEAKNASLTDNQEGHEAE---IERKLEASNLTHND---ELHKEKDDKESIMN 954
+ R L+ A + Q + + IE + A + D EL K+ +D E M
Sbjct: 3573 KMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMK 3632
Query: 953 DLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 774
+ V E+++LES ++ L +L D+E+ +R+ LE K+ L++ D
Sbjct: 3633 E---VLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTD 3689
Query: 773 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 594
L+ +IE K + + + + +I + E + + D + + DI ++ +
Sbjct: 3690 LQGEAEEIE-KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQ 3748
Query: 593 LQEDLNKESKEKQDLEKRV 537
Q++L++ E Q+L++ +
Sbjct: 3749 KQDELDQLKTEIQNLQQEL 3767
Score = 77.8 bits (190), Expect = 4e-11
Identities = 127/620 (20%), Positives = 259/620 (41%), Gaps = 70/620 (11%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQA---LESKVSVFEA 1989
D+ + A+ Q L ++ + L E+ K+ I++ D++ L+ +V
Sbjct: 1361 DQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKE----IMKRDREEIRLLKIEVQRRRR 1416
Query: 1988 AIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD-NN 1812
I ++++ E+D+ + + + + ++ LE ++ ++ ND +E+ ++D NN
Sbjct: 1417 EIEYREEKIMREQDELELM---SKMGQRQREELEERLEEVIKE----NDRVEQMREDVNN 1469
Query: 1811 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
A+ K +D+ D++ QE A++ I S + L L
Sbjct: 1470 AL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKS-YRASDLELSA 1526
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 1452
+QKE+ + K+++ E K +N+I +++ +E ++ E+E E +
Sbjct: 1527 SIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKLHEEEK-EMKTKRV 1582
Query: 1451 AIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------EKTVLERR------ 1323
++ R+ + KEK+ G A+ + KQ L EK+ LE +
Sbjct: 1583 SLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIK 1642
Query: 1322 -------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE------- 1203
AS D +I E + +++ ++ + C E+Q E
Sbjct: 1643 QVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDE 1702
Query: 1202 ------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+T D+E + L++ D + K ++K DL+ + A +
Sbjct: 1703 LSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREK 1762
Query: 1058 QEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAERQVLESKVSDMET 891
+E E+E+ + N D E K E D K ++ + ++++A+R+++E + +E
Sbjct: 1763 EEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALEN 1822
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM------KTGKD 729
L E +ER +E + L++ +LE HD++ + KD
Sbjct: 1823 MKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKD 1882
Query: 728 -DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWLSEVTELQEDLNKE 570
++ E + TL K S++ E IS L + K +++ I I ++ ++Q DLN++
Sbjct: 1883 LENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQ 1942
Query: 569 SKEKQDLEKRVLELTSKLEK 510
KE QD++ V S+L+K
Sbjct: 1943 QKEMQDIQNAVFMEKSELKK 1962
Score = 76.6 bits (187), Expect = 1e-10
Identities = 135/691 (19%), Positives = 273/691 (39%), Gaps = 100/691 (14%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R ++E K+ALEN + + + N D+++ + N ++ + + LE K D
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + T + + ++ + + E +++K V E I+ LN + +KD+
Sbjct: 1870 QQ-LQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQ---QKDE------- 1917
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
+E K ++ + DL+ +T LN + + +D NA+ K L K ++ A Q
Sbjct: 1918 ---IENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQL 1971
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAE 1572
Q DM NL+ I+ ++LQ E+D L ++L + +
Sbjct: 1972 KQVGDMMQFTQNEK-------------DNLDRERAAIIEQKLQMERDMTHLLNRELESLK 2018
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
K+ V LE SL E+ ++ LER + + + EE K +
Sbjct: 2019 LVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQ 2078
Query: 1394 ALVENGEGCE----AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK---------- 1257
L E+ E AEKQ LE +E + + M+ E + ++E VDK
Sbjct: 2079 TLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEI 2138
Query: 1256 ------------SALTENGEGC---------------EAEKQGPEKTVLDLEPTIPSLND 1158
+A+ EN + E+Q ++ V ++E +L D
Sbjct: 2139 TFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-D 2197
Query: 1157 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER----KLEASNLTHNDEL 990
+Q ++D+ E+Q +E + +LE + + L ++++ + E+ + E + N EL
Sbjct: 2198 EMQMEVDK---ERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLEL 2254
Query: 989 HKEKDDKESIMNDLD---------------------------------HVKAERQVLESK 909
E KE + +L+ ++A++ K
Sbjct: 2255 QSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKK 2314
Query: 908 VSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
++T L+++ + E+ E + +E K+ + ++ E+ + +EM+
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM 2374
Query: 728 DDYNEA----------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV------T 597
Y E ++Q +K I ++ + I + ++ K++ I V
Sbjct: 2375 KKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYML 2434
Query: 596 ELQEDLNKESK--EKQDLEKRVLELTSKLEK 510
E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2435 ETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 76.3 bits (186), Expect = 1e-10
Identities = 149/734 (20%), Positives = 298/734 (40%), Gaps = 87/734 (11%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDR----NILEAAKQALEN 2244
+++ LE K ++ ++ +FE + +++D+ N L+ + +EN
Sbjct: 13420 EKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIEN 13479
Query: 2243 KVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALE---------NKVADFEATI 2091
F+ IA L + K DK+ I N+ ++ +Q E N+ +++ +
Sbjct: 13480 ITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKV 13539
Query: 2090 ATLNDELLNEKDDKK-------CIVEADK---------QALESKV-SVFEAAIATLND-- 1968
T EL + K+ KK + +AD Q LE+KV V + T D
Sbjct: 13540 -TYKTELEDSKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLTDYTTQDQE 13598
Query: 1967 ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1788
EL +E ++K I+ + N + Q L+ + E K+ + + LER+++ + + L
Sbjct: 13599 ELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLS 13658
Query: 1787 -----KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH-EEL 1626
++ +K + Q + + + + + E ++ I +E
Sbjct: 13659 LTQEIDHLAQIKTEMQQIEIKMQIQT---------------RSVATQWETDVQIQQGQEA 13703
Query: 1625 QKEKDDKTALIKDLVAAEPGKR-TVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLA 1449
+ T ++ ++A+ K+ TV ++ L S+ + +++ +E ED +A
Sbjct: 13704 TETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMED---------VA 13754
Query: 1448 IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE 1269
MK I + E + + KS + E E + +E+ + E+ + + H++E
Sbjct: 13755 RMKTIMKMEKDQLEQAKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSN 13811
Query: 1268 KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
+DK + E + K + LE TI + + + ++ KQ ++R ++
Sbjct: 13812 TLDK-----KNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQER--EI 13864
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA----ERQV 921
+ ++ +E ++ ++ K E L N E K D + D D K E Q
Sbjct: 13865 QRGTDDTSNEREKYDEKVTYKTE---LEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQT 13921
Query: 920 LESKVSDM-----ETT--YSTLNNELQQKM----DDNEA-----FLNER----------- 822
LE+KV D+ +TT L++E++ KM + NEA L E+
Sbjct: 13922 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVI 13981
Query: 821 -DGLEAVKQGLEK---RVLDLEATI-HDIEMKTGKDDDYNEAEKQT------------LK 693
+ LE + LEK VL L I H ++KT + ++QT ++
Sbjct: 13982 MESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVATQWETDVQIQ 14041
Query: 692 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ E E +T K+++ + VT+L++ L E +E +D + +E +++
Sbjct: 14042 QEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVERMK 14101
Query: 512 KCICGARDGLSTIK 471
+ +D L K
Sbjct: 14102 TMMKMEKDQLEQAK 14115
Score = 72.8 bits (177), Expect = 1e-09
Identities = 142/713 (19%), Positives = 290/713 (40%), Gaps = 73/713 (10%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ + NDRN+L+ + L+ K+ SI D L+ K+A
Sbjct: 5569 EKELLHNDRNLLKKDVEDLQQKL---------------------MSIERDSESLKLDKEA 5607
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE---ATIATL 2082
EN+ + A+ + +L + D+ + I + ++Q +E K A + I TL
Sbjct: 5608 FENE----KEAMKQMKTDLQIQADEIEKIKLE---THHERQRVEEKTAQIQKEREEINTL 5660
Query: 2081 NDELLNEK---DDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
+E+ ++ D+ + +K+A+ES S E A + + N + I RN L
Sbjct: 5661 VEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNAL 5720
Query: 1910 EAAKQALEYKVADLEAAKTTL---NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE 1740
E + + LE K + +ELER D ++A D +S + ++ + E
Sbjct: 5721 EKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQR-QQEAKDHLLSGITDESLLKKSE 5779
Query: 1739 DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKR 1560
+ ++ +S+ + + + + E D K AL KD + +
Sbjct: 5780 AE---IVLQPSQVDKAKPARKTEISDSDKQPVFVQQ--MPEMDLKDALKKDFESEKLDLP 5834
Query: 1559 TVNEIVSHLESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGK 1398
V +++ + + L++ + +E D++ L++ A + K + E +K D
Sbjct: 5835 KVKDVLP--QDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMA 5892
Query: 1397 SALVE------------NGEGCEAEKQG----LEKTVLERRASNLDTMDAIHEEELRKEK 1266
+ L E N + +KQ +EKT ER + +D + ++ K K
Sbjct: 5893 ARLQEERRTNERLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNK 5952
Query: 1265 VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND------ALQRDL-----------D 1137
+ + + E E + K V + SL+ LQ D+ +
Sbjct: 5953 KTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKN 6012
Query: 1136 RVMAEKQALEKRCSD---LEAKNASLTDNQEGHEAEIER-KLEASNLTHN--DELHKEKD 975
+M E L++R SD L+ + L D + A +ER +LE T N ++ K
Sbjct: 6013 TIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKM 6072
Query: 974 DKES-------IMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 816
+KE+ + + D ++ ER++L + + + EL+ + E NE+
Sbjct: 6073 EKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKE 6132
Query: 815 LEAVKQGLEKRVL----------DLEATIHDIEMKTGKDDDYNE--AEKQTLKKRISELE 672
LE +K L+++ + D + ++ + + D +E AE + +++R+ + E
Sbjct: 6133 LEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTE 6192
Query: 671 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ K +K +++ E T+LQ+ + + +++++ ++ EL + E
Sbjct: 6193 K-------KRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKE 6238
Score = 71.2 bits (173), Expect = 4e-09
Identities = 110/577 (19%), Positives = 245/577 (42%), Gaps = 27/577 (4%)
Frame = -2
Query: 2189 EKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALES 2010
EK ++ + +N+ ++L + + + + +L E+++ + I+ + +E
Sbjct: 11741 EKQKEEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRME- 11799
Query: 2009 KVSVFEAAIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1833
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 11800 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 11857
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1659
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 11858 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 11899
Query: 1658 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1479
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 11900 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 11959
Query: 1478 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 1305
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 11960 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 12015
Query: 1304 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 12016 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 12073
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDE--LHKEK 978
+ ++ + +K L+ S+L + L D E++ + E S DE L +E+
Sbjct: 12074 EESMNEMTKKKSELQHERSELYKQKQQLED-MIASESKRDVDTERSRQDKEDEQILKRER 12132
Query: 977 DD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 810
++ K+ ++ + + V+ ++ + + +E S LN++ ++ +N+ L + ++
Sbjct: 12133 EEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQ 12192
Query: 809 AVKQGLEKRVLDLE-------ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILT 651
LEK + DL+ A + + + + D E K+ K +E++ +
Sbjct: 12193 VKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIE 12252
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+L+ + N ++ ++ +L S+E ++L K+
Sbjct: 12253 SVKVRLVTESN----QIDKMNSELKTRSEELENLIKK 12285
Score = 68.6 bits (166), Expect = 3e-08
Identities = 127/670 (18%), Positives = 270/670 (40%), Gaps = 78/670 (11%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
+R LE K AL+++ + E ++ E + + + + +E KQ +EN+ A+
Sbjct: 11542 ERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAE 11601
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
E + + ++ K ++ + + Q E V + T+ DEL +++
Sbjct: 11602 LEIDLENI---IIETKSKQERLESIEVQLQEKNVQM-----GTILDELNKRQEE------ 11647
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
L+A K + + + + DEL I+K+ +++ + + ++D
Sbjct: 11648 ----LDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKD 11703
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE----------LQKEKDDKTAL 1596
Q +M A + +E++ L+L+ E L+K+K++ +
Sbjct: 11704 QFGNMQAELQKGQL-------------EMEMHQLMLNSERDELNGMRVNLEKQKEEFELM 11750
Query: 1595 IKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVLERSASN 1455
++L + P K+ V E+ + L + + E R E+ + +E
Sbjct: 11751 QQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKT 11810
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT-MDAIHE--E 1284
I A EE +KE D + + E CE ++ + + L + + +D D I + +
Sbjct: 11811 KQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEIDIERDEIQKLRK 11866
Query: 1283 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA----------LQRDL-- 1140
+ KEK + + + + E EK E ++ I SL + LQ L
Sbjct: 11867 QYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKLRE 11926
Query: 1139 -----DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEA------------- 1017
D + EK LEK+ +++E DN + E K+EA
Sbjct: 11927 AENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNYLE 11986
Query: 1016 ---SNLTHND---------------ELHKE-KDDKESIMNDLDHVKAERQVLESKVSDME 894
NLT EL+K+ K+ +E M+ ++ +AER+ +E + +M
Sbjct: 11987 QMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERVMDEMA 12046
Query: 893 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY-- 720
+ + E ++ ++ E +R LE + K+ +L+ ++ + + +D
Sbjct: 12047 EEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLEDMIA 12106
Query: 719 NEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+E+++ +R + +E IL + +++ + L E +++ + ++EK+ +EK
Sbjct: 12107 SESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKM 12166
Query: 539 VLELTSKLEK 510
+L + E+
Sbjct: 12167 QSQLNDQKEE 12176
Score = 66.2 bits (160), Expect = 1e-07
Identities = 120/590 (20%), Positives = 242/590 (41%), Gaps = 46/590 (7%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
+R + A+ Q + ++ T+ + DE+ + ++ + + L K ++ E
Sbjct: 6814 ERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKNM-EKTYE 6872
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL----------NDELER 1830
NDE+ EK I + + +L + LE ADLE K + N+ LER
Sbjct: 6873 QQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLER 6929
Query: 1829 KKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1671
+K D II+ +A +R ++ A A +RD E+ M + +
Sbjct: 6930 EKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQEASKNQMV 6988
Query: 1670 --------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH---LESK 1524
+ L+ ++L EL+K K D + DL ++T +EI+ H +SK
Sbjct: 6989 ELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKHEKDTDSK 7042
Query: 1523 SRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENGEGCEAEK 1356
+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 7043 TRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM----------- 7090
Query: 1355 QGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEKQGPEKTV 1194
K V+ +R D M+ I EE+ +E+ + L N + + + +
Sbjct: 7091 ----KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERT 7142
Query: 1193 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEAS 1014
+LE ++ D++R++ E + + +L+ E+ER++E S
Sbjct: 7143 ANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EMERRMEKS 7183
Query: 1013 NLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTLNNELQQK 855
+ DE K + + + D+ ++ L ++ ++E + L + Q++
Sbjct: 7184 KV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQ 7242
Query: 854 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 675
E ER+ LE +K + + D+E +E K++ + Q K+ + +
Sbjct: 7243 ESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSV 7302
Query: 674 EEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 528
E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 7303 TE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 7348
Score = 65.9 bits (159), Expect = 2e-07
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -2
Query: 1565 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1389
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1388 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1209
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1208 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1029
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1028 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 900
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 899 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 723
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 564
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 563 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 399
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 398 RKTSPLDITKT-----CDAVDISEDST 333
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.9 bits (159), Expect = 2e-07
Identities = 125/657 (19%), Positives = 260/657 (39%), Gaps = 68/657 (10%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
I ++ +E++K L + D E A L + DK+ ++ + ++E +K +
Sbjct: 6878 IQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKI 6937
Query: 2114 VADFEATIATLNDELLNE------KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNE 1953
+ + E+ E E +D ++ + + + ++E + + L ++
Sbjct: 6938 IENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQEASKNQMVELKRQIDKL 6997
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---------------ELERKKDD 1818
+ K ++ + L+ K L+ ++ DLE ++ + E++R+KDD
Sbjct: 6998 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 7057
Query: 1817 NNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-- 1656
I+K L+KR + L+++ ++D + M +I +
Sbjct: 7058 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 7117
Query: 1655 -VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSRSLK--- 1509
+ IL +Q + D +TA ++D +A +R V E+V + R+LK
Sbjct: 7118 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVRNLKGEM 7176
Query: 1508 EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLEKTVL 1332
E + + + E+ E+ I + I++ ++R+ G +E + E + + +
Sbjct: 7177 ERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 7236
Query: 1331 ERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT-VLDLE 1182
E++ + +H+E E+ +EK D E E +++ E T + +
Sbjct: 7237 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 7296
Query: 1181 PTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1011
+ S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +K E
Sbjct: 7297 EELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-KKGEQLL 7355
Query: 1010 LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 831
DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 7356 EKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDLFRSELQ 7415
Query: 830 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------------ 687
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 7416 RQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKIRFDIAN 7472
Query: 686 ----ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 528
I + + IL D + +D + E +L E D+E+ VLE+
Sbjct: 7473 ARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLVLEV 7525
Score = 64.3 bits (155), Expect = 5e-07
Identities = 123/636 (19%), Positives = 256/636 (40%), Gaps = 49/636 (7%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E AK +++ + E + DE+ E + K I + ++ DK ALE + D
Sbjct: 453 IEQAKVDIQSHMISMEGRV----DEIKRETERLKHIKTE---MQRDKDALEKQKDDTRKA 505
Query: 2093 IATLND---ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLND----ELLNEKDDKKC 1935
E++ E+ + + ++ ++ LE+ A + +ND ++L EK++
Sbjct: 506 KEEAERKRYEIVTEELEHRARLQRERDELEN----IRAEMQRVNDVEKAKILKEKEES-- 559
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAP 1755
+ R ++ E A+++A K LN E + I +RI A
Sbjct: 560 -IRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEI------ERIKHETLRAK 612
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
+ + E+ + I + ++E + EE+QK K+ +L
Sbjct: 613 E-EIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKV----EEIQKTKEQMEEAKVELEEE 667
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEED-------------EVLERSASNLAIMKAI 1434
++VS ++ L+ LR +E+ E+ ++ L ++ +
Sbjct: 668 REDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLEKL 727
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
REE R +K+ + + +E L K L++ ++ + ++ + K +
Sbjct: 728 REETERSQKNIEESKIE---------LMLWKESLDKLKGEMEEDKHVVIMQMNEAKAKEE 778
Query: 1253 ALTENGEGCEAEKQ----GPEKTVLDLEPTIPSLNDALQR------DLDRVMAEKQALEK 1104
LT E E E+ EK +L+ I + + LQR D RV+ K+ E
Sbjct: 779 QLTMVIEQLEIERGEITISREKVKEELDE-INRMRNELQRQHAEMEDWFRVV-NKEKEEA 836
Query: 1103 RCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDELHKEKDDKESIMNDLDHVKAE- 930
+ L A + ++ E+E R ++ L DE+ K+ ++ E I ++ + E
Sbjct: 837 NLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAEELEQINKEIQRARQEL 896
Query: 929 -----------RQVLESKVSDMETTYSTLNNELQQKMDDNEAFL---NERDGLEAVKQGL 792
+++LE + + L+ K D ++ +ER LE ++ +
Sbjct: 897 EKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSERKELEQMRFQV 956
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL---EEAISILTDKAKKLLKDI 621
E DLE +++ + + +K+ L+K S+L E+++ + A++ +
Sbjct: 957 ENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKA 1016
Query: 620 NIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ + E+ E +ED+NK +E + E+ + L +E
Sbjct: 1017 ELLIVEIQEQREDVNKRLEETKQREEALRLLRKDME 1052
Score = 63.5 bits (153), Expect = 8e-07
Identities = 123/686 (17%), Positives = 275/686 (40%), Gaps = 44/686 (6%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++DK V+ N +A ++ L + E I RN L+
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 2258 QALEN--KVGDFEAAIATLNDELLNEKD---DKKCIVNDRNIVEADKQALENK--VADFE 2100
+E+ +V + E A L ++E + K+ +++ E +ALE + +
Sbjct: 820 AEMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKA 879
Query: 2099 ATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA---IATLNDELL-NEKDDKKCI 1932
+ +N E+ + + + + +K++L+ + + + + ELL N+ D KC+
Sbjct: 880 EELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCL 939
Query: 1931 V---NDRNILEAAKQALEYKVADLEAAKTTL-------NDELERKKDDNNAIIKKALDKR 1782
++R LE + +E + DLE + + + +++R+K++ I + +
Sbjct: 940 FEMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDT 999
Query: 1781 ISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
S ++ R + LI + E + +L ++++ E++D
Sbjct: 1000 ESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENERED-- 1057
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE 1422
L K V GK T E+ + ++ + E+ + ER N + IR+ E
Sbjct: 1058 -LEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKME 1116
Query: 1421 LRKEKDGK--SALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR-KEKVDKSA 1251
K + G+ VE + E +E LE +NL+ M A + LR KE ++
Sbjct: 1117 AMKREMGEIEDMKVELTKQKENIDMKMEHARLEM--TNLEMMKA---DLLRQKEDIENQM 1171
Query: 1250 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
L E + E E +L + + + + +++++ K ++K+ +LE +
Sbjct: 1172 LAAKSERQQMEVMRTE--ILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 1070 LTDNQEGHEAEIERKLEASNLTHNDELH---KEKDDKESIMNDLDHVKAERQVLESKVSD 900
T + G ++R++E + + ++K++ E + ++ K + + +
Sbjct: 1230 -TKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQRAKDDMEFKRVETER 1288
Query: 899 METTYSTLNNELQQKMDDNEAFLNERD-----------------GLEAVKQGLEKRVLDL 771
+ + E+Q+ ++ E + ERD +EA ++ + K
Sbjct: 1289 QKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIINLIQQIEATREMVHKTKFQF 1348
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
E + +M T ++ N AE Q L I + E + L + ++ + + E+ L
Sbjct: 1349 ENRMAGSQMGTADQEEMN-AEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLL 1407
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLE 513
+ ++ + +E + E++++ +LE
Sbjct: 1408 KIEVQRRRREIEYREEKIMREQDELE 1433
Score = 61.2 bits (147), Expect = 4e-06
Identities = 115/678 (16%), Positives = 265/678 (39%), Gaps = 38/678 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++ + + + +E K ++ ++ D E + + +R LE +
Sbjct: 616 ENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKR 675
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLN 2079
+ ++ E L +E+L K+ E + + E + + E T +
Sbjct: 676 DLVSREIEQAEF----LRNEILRVKE------------EMESRWRETETEEVELRAKTQH 719
Query: 2078 D----ELLNEKDDKKCIVEADKQALESKVSV--FEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ E L E+ ++ + K ESK+ + ++ ++ L E+ ++DK ++ N
Sbjct: 720 ELERLEKLREETER-----SQKNIEESKIELMLWKESLDKLKGEM---EEDKHVVIMQMN 771
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQED 1737
+A ++ L + LE + + E+ K++ + I ++ ++L+ Q
Sbjct: 772 EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEI-----NRMRNELQR------QHA 820
Query: 1736 DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK-TALIKDLVAAEPGKR 1560
+M V E+ + EE +K + + T ++ +
Sbjct: 821 EMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAE 880
Query: 1559 TVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALV 1386
+ +I ++ + L++ +F +E ++LE + ++ +R E L+ + D L
Sbjct: 881 ELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLF 940
Query: 1385 E-NGEGCEAEKQGL----EKTVLERRASNLDTMDAIHEEELRKEK-----------VDKS 1254
E + E E E+ EK LE+R + D +++++K +D
Sbjct: 941 EMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTE 1000
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMA----------EKQALEK 1104
++ + E +++ E +++++ +N L+ R A E++ LEK
Sbjct: 1001 SMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDLEK 1060
Query: 1103 -RCSDLEAKNASLTDNQEGHE--AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA 933
R L K+ +E + AEIER + + +E K +KE ++ ++ +K
Sbjct: 1061 IRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKR 1120
Query: 932 ERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHD 753
E ++ DM+ + + KM+ E LE +K L ++ D+E +
Sbjct: 1121 EM----GEIEDMKVELTKQKENIDMKMEHARL---EMTNLEMMKADLLRQKEDIENQM-- 1171
Query: 752 IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+ + E + + K+ ++E + + + +K+ + + EL+E + K
Sbjct: 1172 --LAAKSERQQMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 572 ESKEKQDLEKRVLELTSK 519
+E ++E E+ K
Sbjct: 1230 TKREIGEMELMKREMEGK 1247
>ref|XP_009292628.1| PREDICTED: nesprin-1 isoform X4 [Danio rerio]
Length = 15654
Score = 116 bits (291), Expect = 8e-23
Identities = 145/673 (21%), Positives = 300/673 (44%), Gaps = 29/673 (4%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I +L+ + + K D++ N+R +++ K LE + + E
Sbjct: 6054 IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKI 6113
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + + K I +D++
Sbjct: 6114 KLETQHDR--QRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKD 6171
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-R 1749
+LE K LE ++L K ++LE++K++ A I+K L+K ++ + + +
Sbjct: 6172 MLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQIQKEREDLEKMNENITREMHEIK 6227
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLV 1581
QE+ MN + L+ I L +EL+KEK+ ++ L +
Sbjct: 6228 HQEEQMNQ--------------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQS 6273
Query: 1580 AAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
+ + +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+L+ K
Sbjct: 6274 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKL 6333
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTEN 1239
K + E E K LE+ + R +T + EEL+KE+ D + L E+
Sbjct: 6334 QKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED 6393
Query: 1238 GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+ EK ++ + E ++ L Q++ + K+ + K+ D+E + D
Sbjct: 6394 ---TKREKNSLDEMKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DK 6442
Query: 1058 QEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYST 879
E E+E+ L+A E+HK++ + E + +++ ER + V D+++ +
Sbjct: 6443 IRLREDELEQ-LQA-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIIS 6491
Query: 878 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDD 723
L+ + + D EAF NE++ L+ +K LE+ ++E T H+ EM +
Sbjct: 6492 LDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMET 6551
Query: 722 YNEAEKQTLKKRI------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 561
N KQ K ++ E+E+ + K L +D+ + ++ L+E+ NK +
Sbjct: 6552 MNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQM 6611
Query: 560 KQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPL 381
K LE+ E+ SK+++ R L + A + E L + RK L
Sbjct: 6612 KIGLEREADEI-SKIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVL 6661
Query: 380 DITKTCDAVDISE 342
D K + +++
Sbjct: 6662 DKIKVANESTLAD 6674
Score = 112 bits (280), Expect = 2e-21
Identities = 144/655 (21%), Positives = 283/655 (43%), Gaps = 63/655 (9%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ E KQ +E + D
Sbjct: 4293 EKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHD 4352
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
F+ + +L+++L K K+ I E + + K+ + A DE+ K++ + N
Sbjct: 4353 FDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREA-----DEIRKVKEETQ---N 4404
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
+R I E +AL+ + DL N L+ K N + + L +R S+L ++
Sbjct: 4405 ERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRER-SNL------QE 4457
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLVA 1578
++++ + + L+ I E +KEK ++ A+IKD+
Sbjct: 4458 MRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVED 4517
Query: 1577 AEPGKRTVNEIVSHLESKSRSLK---EHFLREEED-----EVLERSASNLAIMKAIREEE 1422
+ ++I+S L+ + SLK E F E+E+ LER A + +K + E
Sbjct: 4518 LQ------SKIIS-LDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHE 4570
Query: 1421 LRKEKDGKSALVE--NGEGCEAEKQGLE----KTVLERRASNLDTMDAIHEEELRKEKVD 1260
++ ++ + +E N E + K E K +E+ ++D ++ L+ K+
Sbjct: 4571 RQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQ 4630
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK 1080
K + E EK E+ ++LE D +++ + E+Q LEK +L+ +
Sbjct: 4631 KQVI-------EEEKNKLEQMKIELEKEA----DEIRKIKEETQNERQRLEKMTEELKKE 4679
Query: 1079 NASLTDNQEGHEAE--IERKLEASNLTHNDELHKEKDDKESIM----------------- 957
S T E + E I K++ +N + +L KEK + E +
Sbjct: 4680 KESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKI 4739
Query: 956 ----NDLDHVKA------------------ERQVLESKVSDMETTYSTLNNELQQKMDDN 843
++L+ ++A ER + V D++ +L+ +L+ D
Sbjct: 4740 RLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDR 4799
Query: 842 EAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAI 663
EAF NER+ L+ +K L+++ ++E I+++T D E ++K ++ I
Sbjct: 4800 EAFENEREVLKQIKTDLKRKAEEIE----KIKLETQHDRQRVEEMTAQIQKERDKINNLI 4855
Query: 662 SILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEK---RVLELTSKLEK 510
T++ +L +I + E + ++ D + KEK DLEK ++L LEK
Sbjct: 4856 E-ETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEK 4909
Score = 112 bits (280), Expect = 2e-21
Identities = 150/630 (23%), Positives = 279/630 (44%), Gaps = 43/630 (6%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT- 2094
E+ + A+ V D + + +L+ +L + K D++ N+R +++ K L+ K + E
Sbjct: 4768 ESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIK 4827
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ T +D E+ + E DK + + + LN+ K+ K I +DR++
Sbjct: 4828 LETQHDRQRVEEMTAQIQKERDK--INNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDM 4885
Query: 1913 LEAAKQALEYKVADLEAAKTTLND-------ELERKKDDNNAIIKKALDKRISDLKADAP 1755
LE K LE + L AK L E++++++D + +K I D+K
Sbjct: 4886 LEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEK-FTIEIHDIKHQEE 4944
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKD 1587
Q Q+ D + L+ I L +EL+KEK+ D++ L D
Sbjct: 4945 QMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL--D 4982
Query: 1586 LVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELR 1416
L +E K+ VN+I+ ++++ + L K+ EE+ + +E+ + + +E+L+
Sbjct: 4983 LRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLK 5042
Query: 1415 KEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 1236
K K L + E K LE+ +E R + I E EK+ + AL E
Sbjct: 5043 MMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK----EEIQNERQNLEKMTE-ALKEER 5097
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1056
E E + + + +++ S + R+ + ++ + K+ D+E K +N
Sbjct: 5098 EDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK----ENL 5153
Query: 1055 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E E+ R+L+A E+ KEK + ES ER + V D++ L
Sbjct: 5154 RLREDEL-RQLQAEIHKQQREIEKEKINIES----------ERAAIIKDVEDLQHKIICL 5202
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD--------IEMKTGK 732
+ + + D EAF NE++ L+ +K LE+ ++E T HD +++ +
Sbjct: 5203 DRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDR 5262
Query: 731 DDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLN 576
D+ N E+ L ++ ++EE I SI +DK +K D+ SE+ +++EDL
Sbjct: 5263 DEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLE 5322
Query: 575 KE--------SKEKQDLEKRVLELTSKLEK 510
K+ KE++DLEK +T ++ +
Sbjct: 5323 KQKENTLAEIQKEREDLEKMNENITREMHE 5352
Score = 110 bits (276), Expect = 5e-21
Identities = 145/650 (22%), Positives = 280/650 (43%), Gaps = 52/650 (8%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
++ KQ +E + D + + +L+ L K K+ I ++N +E K LE + +
Sbjct: 4599 MQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKI 4658
Query: 2093 ----------IATLNDELLNEKDDKKCIVE---ADKQALESKVSVFEAAIATLNDELLNE 1953
+ + +EL EK+ + E +K+ L+ E+ +A L E N
Sbjct: 4659 KEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNL 4718
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNN----AIIKK- 1797
++ ++ I E K+ + + +LE + ++ E++ +K +N AIIK
Sbjct: 4719 EEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDV 4778
Query: 1796 --------ALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VNIL 1644
+LD+ + LK D + E ++ I K+ + + +
Sbjct: 4779 KDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVE 4838
Query: 1643 ILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK-EHFLREEEDEVLER 1467
+ ++QKE+D LI++ + +NEI + ++ K ++++ + + E+E LE+
Sbjct: 4839 EMTAQIQKERDKINNLIEETNRKD---MVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEK 4895
Query: 1466 SASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 1287
+ S L K E L K++ K A ++ E++ LEK ++ D H+
Sbjct: 4896 TRSKLLRAK----ENLEKQRKIKLAEIQK------EREDLEKM---NEKFTIEIHDIKHQ 4942
Query: 1286 EELRKEKVDKSALTENGEGCEAEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQAL 1110
EE K+K D+ LD L+ I +L L+++ + +M ++ L
Sbjct: 4943 EEQMKQKQDE---------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL 4981
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----KESIMNDL 948
+ R S+L+ + ++ D E + E ++ K + E+ KEK D ++S+ DL
Sbjct: 4982 DLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDL 5041
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
+K ++QVLE + S +E L E + E NER LE + + L++ DL
Sbjct: 5042 KMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL- 5100
Query: 767 ATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISILTDKAKKLLKDINIWLS 606
+ + D+ A + TL K + E+ E IS T+ + +++ +
Sbjct: 5101 --AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLRED 5158
Query: 605 EVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCICGARDGLS 480
E+ +LQ +++K+ KEK ++E + +E K IC RD S
Sbjct: 5159 ELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAES 5208
Score = 110 bits (275), Expect = 6e-21
Identities = 135/650 (20%), Positives = 282/650 (43%), Gaps = 65/650 (10%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ + + + + + +ND + K+++K + D+ +E KQ +E + D
Sbjct: 5840 EKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHD 5899
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
F+ + +L+ +L K K+ E + + K+ + A + +
Sbjct: 5900 FDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKM 5959
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1806
+EL EK+ + D + IL+ K A E +ADL+ K+ L + E +
Sbjct: 5960 TEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDV 6019
Query: 1805 IKKALDKRISD-----LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1641
K + R+ + L+A+ ++ +E + + I+ N+E +
Sbjct: 6020 ENKKENLRLREDELWQLQAEIYKQQREIEKEKI--------NIESERAAIIKNVED---L 6068
Query: 1640 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE------ 1479
H+ + ++D + +L D A E + + ++ + LE ++ +++ L + D
Sbjct: 6069 QHKIISLDRDSE-SLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEM 6127
Query: 1478 ----VLERSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---- 1338
+R N I + R++ + EK+ ++ + + E EK LEKT
Sbjct: 6128 TAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSEL 6187
Query: 1337 -----VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEP 1179
LE++ N T+ I +E EK++++ E E E+Q +K + L+
Sbjct: 6188 YKVKEDLEKQKEN--TLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 6245
Query: 1178 TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLT 1005
I +L L+++ + +M + L++R S+L+ + ++ D E + E ++ K +
Sbjct: 6246 EIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 6305
Query: 1004 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 837
E+ KE+D+ ++S+ DL +K ++QV+E + + +E L E E
Sbjct: 6306 QKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEE 6365
Query: 836 FLNERDGLEAVKQGLEKRVLDLEATIHDI--------EMKTGKDDDYNEAEKQTLKKRIS 681
N+R LE + + L+K D+ D EMK + + +K+ K +
Sbjct: 6366 TQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKE--KSNLE 6423
Query: 680 ELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 531
E++E IS T+ +K I + E+ +LQ +++K+ E ++EK +E
Sbjct: 6424 EMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSE-TEIEKSNIE 6472
Score = 108 bits (270), Expect = 2e-20
Identities = 151/639 (23%), Positives = 281/639 (43%), Gaps = 55/639 (8%)
Frame = -2
Query: 2261 KQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL 2082
K+ L N + L +L++ + D K + DR E +K+A++ D + +
Sbjct: 5634 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 5693
Query: 2081 NDELLNEKDDKKCIVEADKQALESKVSVFEAAIAT-LNDELLNEKDDK-----KCIVNDR 1920
L + D++ + E Q + + + T D +LNEK+ K I +D+
Sbjct: 5694 EKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDK 5753
Query: 1919 NILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
++LE + LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 5754 DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM-NENITREMHEIKHQ 5812
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q +Q+ D + L+ I L +EL+KEK+ D++
Sbjct: 5813 EEQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQF- 5851
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ + + +++
Sbjct: 5852 -DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKD 5910
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-----EELRKEKVDK 1257
L+ K K E E K LE+ E R +T + EEL+KEK
Sbjct: 5911 LKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESF 5970
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1077
+ L E+ + E+ +LD + N++L DL + EK LE+ ++ +
Sbjct: 5971 THLAEDTK--------KEQEILD---KVKVANESLMADLQK---EKSNLEEMRENISKQT 6016
Query: 1076 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
+ + +E + +L+A E+ KEK + ES ER + V
Sbjct: 6017 EDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIES----------ERAAIIKNVE 6066
Query: 902 DMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEM 744
D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T HD +E
Sbjct: 6067 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 6126
Query: 743 KTG---KD-DDYNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSE 603
T KD D N ++T L ++ ++E+ I SI +DK +K D+ SE
Sbjct: 6127 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSE 6186
Query: 602 VTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 6187 LYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHE 6225
Score = 106 bits (265), Expect = 9e-20
Identities = 138/669 (20%), Positives = 296/669 (44%), Gaps = 31/669 (4%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAA 2262
EKDD ++ D + + L E+A+A +S+ ++++
Sbjct: 3517 EKDDLAHLAEDTKRKDDEMKVLH------ESALADIQKEKCNLEQMRESMFKQNEMIDSE 3570
Query: 2261 KQAL---ENKVGDFEAAIATLNDELLNEKDDKKCIV-NDRNIVEADKQALENKVADFEAT 2094
K+ + E+K+ +A I E+ D KK I+ N+R + Q L ++
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEM----DTKKSIIENERAAMTKKNQDLMTELTKQSED 3626
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ E+L EK+ ++E+D++ L+ V + + + + + K D++ + N++ +
Sbjct: 3627 VEIQMKEVLTEKE----LLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEV 3682
Query: 1913 LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDD 1734
L+ K L+ + ++E K E +R ++ A I+K DK I++L + ++D
Sbjct: 3683 LKQMKTDLQGEAEEIEKIKLETQHERQR-VEEMTAQIQKERDK-INNLIEETNRKDMV-- 3738
Query: 1733 MNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTV 1554
L + E+++ + DK L K+ E + +
Sbjct: 3739 ------------------------LNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSEL 3774
Query: 1553 NEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI-MKAIR--EEELRKEKDG----KS 1395
++ LE + + +E ED LE+ N+ I M I+ EE++++++D K+
Sbjct: 3775 YKVKEDLEKQKENTLAEIQKERED--LEKMNENITIEMHEIKHQEEQMKQKQDELDQLKT 3832
Query: 1394 ALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 1221
+ + E EK+ + +++ L+ R S LD + + K ++ L ++ E E
Sbjct: 3833 EIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEE 3892
Query: 1220 EKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA 1041
+KQ EK +++ +I SL++ DL + +KQ +E+ + LE L EA
Sbjct: 3893 QKQEMEKERDNMDQSIKSLDE----DLKMMKLQKQVIEEEKNKLEQMKFELQ-----REA 3943
Query: 1040 EIERKLEASNLTHNDELHKEK----DDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 873
+ RK++ L K ++E +++ ++ K E+++L+ +M+ +
Sbjct: 3944 DEIRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKREKEMLD----EMQVANKSSM 3999
Query: 872 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE-----ATIHDIEMKTGKDDDYNEAE 708
+LQ+ E+ LE +++ + K+ D+E + + + E+K + + +
Sbjct: 4000 ADLQR----------EKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQS 4049
Query: 707 KQTLKKRISELEEAISI-----LTDKAKKLLKDINIWLSEV-TE---LQEDLNKESKEKQ 555
+ ++K E E A+ I + + KK +D+ I + E+ TE L+ D N K+ +
Sbjct: 4050 EIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDME 4109
Query: 554 DLEKRVLEL 528
DL+++++ +
Sbjct: 4110 DLKQKLMSI 4118
Score = 105 bits (263), Expect = 1e-19
Identities = 126/642 (19%), Positives = 281/642 (43%), Gaps = 46/642 (7%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLND-------ELLNEKDDKKCI-------VN 2160
+I +DR++LE K LE A L E+ E++D + + ++
Sbjct: 4878 AIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIH 4937
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
D E + ++++ + I L EL EK+ I+ D+ L+ + S +
Sbjct: 4938 DIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKE----IIMKDRSQLDLRQSELDKQQT 4993
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII- 1803
+ND + K+++K + D+ E KQ +E + D + ++ +L+++L+ K +
Sbjct: 4994 NVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLED 5053
Query: 1802 -KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
K L++ +L+ +A + + +E+ N + + N +L E
Sbjct: 5054 EKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDE 5113
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFLREEEDEV------ 1476
+ ++++ E + +++ +E+K +L+ E LR+ + E+
Sbjct: 5114 MKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQRE 5173
Query: 1475 LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAEKQGLE--KTVLER 1326
+E+ N+ AI+K + + + + ++D +S ++ E E EK+ L+ KT LER
Sbjct: 5174 IEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENEKEVLKQMKTELER 5232
Query: 1325 RASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQR 1146
A ++ + E + +++V++ A + E E D+ + N ++
Sbjct: 5233 EADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM--VLNEKNRDIEE 5288
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ + ++K LEK DLE + L +E E + E L E+ KE++D
Sbjct: 5289 KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA--------EIQKEREDLE 5340
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
E+I ++ +K + + + K +++ + + N Q+ + E + +R L+ +
Sbjct: 5341 KMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQS 5400
Query: 797 GLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 627
L+K+ + D+ T+ + + KD + E +KQ ++K ++++ L + KK+
Sbjct: 5401 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKL 5460
Query: 626 DINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 510
++ E +L++ +L +E+ E +++ +LEK
Sbjct: 5461 QKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 5502
Score = 104 bits (259), Expect = 4e-19
Identities = 127/622 (20%), Positives = 279/622 (44%), Gaps = 40/622 (6%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I L+ + + K D++ N++ +++ K LE + + E
Sbjct: 5181 IESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKI 5240
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + ++ K I +D++
Sbjct: 5241 KLETQHDR--QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5298
Query: 1916 ILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+LE K LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 5299 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKM-NENITREMHEIKHQE 5357
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIK 1590
Q +Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 5358 EQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL-- 5395
Query: 1589 DLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+
Sbjct: 5396 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQ 5455
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKT------VLERRASNLDTMDAIHEEELRKE---- 1269
+K K K E E K LE+ + E + ++ + EE +R++
Sbjct: 5456 KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLA 5515
Query: 1268 ------KVDKSALTEN---GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1116
K +K L E E A+ Q + + ++ I L + + + ++ +
Sbjct: 5516 HLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLRED 5575
Query: 1115 ALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNLTHNDELHKEKDDKE----SIMND 951
L+K ++++ + + + + E+E + E N+ EL K+ +D E I+ +
Sbjct: 5576 ELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMM--TELKKKSEDVEIQMKEILTE 5633
Query: 950 LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 771
+ + +R++L V +++ L + ++ D EAF NE++ ++ +K L+ + ++
Sbjct: 5634 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 5693
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE-VTE 594
E I+++T D E ++K ++ I T++ +L + N + E +
Sbjct: 5694 E----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE-ETNRKDMVLNEKNRDIEEKIKS 5748
Query: 593 LQEDLNKESKEKQDLEKRVLEL 528
+Q D + KE+ +LEK EL
Sbjct: 5749 IQSDKDMLEKERHNLEKTRSEL 5770
Score = 100 bits (250), Expect = 5e-18
Identities = 127/675 (18%), Positives = 292/675 (43%), Gaps = 46/675 (6%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ + +++++L K L+N+ + + ++ +++ +
Sbjct: 11877 ERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEE 11936
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N++ + + + + +R + + L+ ++ +F+A ++ +E
Sbjct: 11937 TRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEE 11996
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L ++ + K E K E+K ++ E +E+ EK+ ++ R +E ++
Sbjct: 11997 DLPKEKEMK---EDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKE 12053
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNAL 1722
+E + LE ++ ++ E ++ DD I K+ L+K S++ Q ++E +++
Sbjct: 12054 IEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKK 12113
Query: 1721 IXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK-----------DDKTALIKDLVAA 1575
I +IV L V + E+Q +K D++ LI++ +
Sbjct: 12114 IKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQ 12173
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEEL 1419
+ + E+ ++ + +LKE + +EE + V+E R +L M E+
Sbjct: 12174 QNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQK 12233
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI-----------HEEELRK 1272
+ + + L + E E+ + T L++R +T I +E+L++
Sbjct: 12234 QDLMNQRDLLKQ-----EREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQ 12288
Query: 1271 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1092
+ ++ E E + E + ++ D L+++ E++ L+K+ D
Sbjct: 12289 AIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADD 12348
Query: 1091 LEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAE 930
LE + D +E + + E+KL + +N L D+L KEK+D N+LD ++ E
Sbjct: 12349 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 12408
Query: 929 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEAT 762
Q ++++ +++ T E+ ++ E LN ER LE V+ EK +
Sbjct: 12409 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQ 12464
Query: 761 IHDIEMKTGKD-DDYNEAEKQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
I ++ +KT + D+ ++ + L +K ++ I +L + ++ +++ ++ EL
Sbjct: 12465 IEEMRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEEL 12521
Query: 590 QEDLNKESKEKQDLE 546
+ + K EK+DLE
Sbjct: 12522 KLEKQKIQNEKKDLE 12536
Score = 100 bits (248), Expect = 8e-18
Identities = 135/693 (19%), Positives = 298/693 (43%), Gaps = 107/693 (15%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ +E KQ +E + +
Sbjct: 6257 EKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDN 6316
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
+ + +L+++L K K+ I E + + K+ + A + +
Sbjct: 6317 MDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKM 6376
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------EL 1836
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++
Sbjct: 6377 AEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDI 6436
Query: 1835 ERKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXX 1698
E++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6437 EKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDA 6496
Query: 1697 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LE 1530
+ N + + + EL++E D+ + K + + ++ V E+ + +
Sbjct: 6497 ESLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMN 6553
Query: 1529 SKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQ 1353
++ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K
Sbjct: 6554 NERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKI 6613
Query: 1352 GLE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEA 1221
GLE K + NL+ M +A+ EE E++++ + E A
Sbjct: 6614 GLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLA 6673
Query: 1220 EKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA 1041
+ Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+
Sbjct: 6674 DLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIES 6733
Query: 1040 EIERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E + E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 6734 ERAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSI 6791
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK----- 732
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6792 ERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKER 6851
Query: 731 -----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 609
D+ Y E EK+ ++ S+LE+A S + K K+I I L
Sbjct: 6852 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIAL 6907
Query: 608 SEVTELQEDLNKESKE------KQDLEKRVLEL 528
+E+ + + L K SKE K + EK+ ++L
Sbjct: 6908 AEIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 6940
Score = 99.4 bits (246), Expect = 1e-17
Identities = 143/698 (20%), Positives = 299/698 (42%), Gaps = 53/698 (7%)
Frame = -2
Query: 2249 ENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL-NDE 2073
++++ + I L EL EK+ I+ DR+ ++ + L+ + + I T+ N+
Sbjct: 3824 QDELDQLKTEIQNLQQELEKEKE---IIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 3880
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L +KD ++ +E KQ +E + + +I +L+++L K K+ I ++N LE K
Sbjct: 3881 KLLDKDKEE--MEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFE 3938
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMNALI 1719
L+ + ++ K +E + + A+IK+ D + L A+ +R++E D+M
Sbjct: 3939 LQREADEIRKIKEETQNERQSLEKMTKALIKERED--LVHL-AEYTKREKEMLDEMQVA- 3994
Query: 1718 XXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 1539
+I+ + NI E+++ EK+ +L + + +
Sbjct: 3995 --NKSSMADLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEID 4052
Query: 1538 HLESKSRSLKEHFLREEEDEV--LERSASNLAI-MKAIREEELRKEKDGK---------- 1398
++ S + +RE+++ + L++ + ++ I MK I E+ E D
Sbjct: 4053 MEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLK 4112
Query: 1397 ---SALVENGEGCEAEKQ--GLEKTVLERRASNLDTMDAIHEEELRKEKV----DKSALT 1245
++ + E + +++ G EK VL++ ++L I +E+ K K+ D+ +
Sbjct: 4113 QKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQ----IQADEIEKIKLETQHDRQRVE 4168
Query: 1244 ENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR----VMAEKQALEKRCSDLEAKN 1077
E + ++ +++ LN+ + RD++ + ++K LEK +LE
Sbjct: 4169 EKTAQIQKDRDEINNLIVETNRKDMVLNE-MDRDIEEKIKSIQSDKDMLEKERHNLEKTR 4227
Query: 1076 ASLTDNQEGHEA--EIERK----------LEASNLTHNDELHKEKDD-----KESIMNDL 948
+ L +E E EIERK E + H +E K+K D K I N
Sbjct: 4228 SELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQ 4287
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
++ E++++ S ++ S L+ + D E NER L+ K+ E++ ++E
Sbjct: 4288 QELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEME 4347
Query: 767 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS-EVTEL 591
HD + D+ + + L+K++ E E K LK + I L E E+
Sbjct: 4348 KEKHDFDQSRKSLDE--DLKMMKLQKQVIEEE----------KSKLKQMKIELEREADEI 4395
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLEKCICGAR------DGLSTIKEAWMSDCMVPDNWV 429
++ + E+Q EK L + E A+ D + E+ ++D + +
Sbjct: 4396 RKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERS-- 4453
Query: 428 PFEDLVQGFSRKTSPLDITKTCDAVDISEDSTTNIQVD 315
+++ + S++T D+ + + + E+ +Q +
Sbjct: 4454 NLQEMRENISKQTE--DVENKKEKIRLREEKLKQLQAE 4489
Score = 99.4 bits (246), Expect = 1e-17
Identities = 138/664 (20%), Positives = 294/664 (44%), Gaps = 74/664 (11%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R+++E ++ + + + N +L+N++D K +R + L+ ++ +F
Sbjct: 11375 RSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLK---QEREEINHKWTQLQQRIDEF 11431
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+A ++ +E L ++ K + E K E+K+ + E T +++ EK+ ++ V
Sbjct: 11432 DAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVM- 11487
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
R +E K+ L+ + LE ++ ++ E ++ DD I K+ L+K S++ Q
Sbjct: 11488 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11547
Query: 1748 DQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEV-------NILILHEEL----QKEKDDK 1605
++E +++ I +IV L V +I + EEL QK D++
Sbjct: 11548 EEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQ 11607
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE---HFLREEED-------------EVL 1473
++++ + + E+ ++ + +LKE H +E+E+ E L
Sbjct: 11608 GLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDL 11667
Query: 1472 ERSASNLA-----------IMKAIREE------ELRKEKDGKSALVENGEGCEAEKQGLE 1344
E+ ++++ ++K REE +L++ D A V + + KQ
Sbjct: 11668 EKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQ--- 11724
Query: 1343 KTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 1170
K + E R S +T I E + + E K+ K E E A+ + ++ + ++ +
Sbjct: 11725 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLE 11784
Query: 1169 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHN 999
+ + + ++ +K+ +E+ DLE + + ++ E +E+E K+ + +
Sbjct: 11785 RVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKC 11844
Query: 998 D-ELHKE---------KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 849
D E KE ++ K I + + ERQ + + + S L NE ++ +
Sbjct: 11845 DIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKN 11904
Query: 848 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD-----DYNEAEKQTLKKRI 684
NE ER+ L+ ++ LEK ++++ E + K+D + +KQ L+ +
Sbjct: 11905 INEVIKKERETLKEMEAYLEKEKEEMKSITE--ETRRQKEDLEKMSTHINEQKQDLRSQR 11962
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVT-ELQEDLNKESKEKQD------LEKRVLELT 525
LE+ + K K+L + I+ + ++V+ + +EDL KE + K+D + +LE+
Sbjct: 11963 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK 12022
Query: 524 SKLE 513
+K E
Sbjct: 12023 TKAE 12026
Score = 98.2 bits (243), Expect = 3e-17
Identities = 142/710 (20%), Positives = 297/710 (41%), Gaps = 62/710 (8%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ ++ DR+ L+ + L+ + + + T + N+R L+ K+
Sbjct: 5384 EKEIIMKDRSQLDLRQSELDKQQTNMNDIMET--------------MKNERKQLDKDKEE 5429
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE--------- 2100
+E + + E ++ + +D+K + + + E +K LE + E
Sbjct: 5430 MEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKI 5489
Query: 2099 --------ATIATLNDELLNEKDD----------KKCIVEADKQALESKVSVFEAAIATL 1974
+ + +EL+ EK+ +K I++ K A ES ++ + + L
Sbjct: 5490 KEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL 5549
Query: 1973 NDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 1794
+ N K+ I N++ + + L+ +++ ++ ++ E + + A+I++
Sbjct: 5550 EEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREK 5609
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
+++LK + D E M ++ + V NL+ ++ L + ++ K
Sbjct: 5610 -QNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLK 5666
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV---LERSASNLAIM 1443
D+ A + A + K + +E + R EE ER N I
Sbjct: 5667 LDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIE 5726
Query: 1442 KAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---------VLERRASNLDT 1305
+ R++ + EK+ ++ + + E E+ LEKT LE++ N T
Sbjct: 5727 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN--T 5784
Query: 1304 MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEPTIPSLNDALQRDLDRV 1131
+ I +E EK++++ E E E+Q +K + L+ I +L L+++ + +
Sbjct: 5785 LAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 5844
Query: 1130 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----K 969
M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D +
Sbjct: 5845 MKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSR 5904
Query: 968 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 789
+S+ DL +K ++QV E + + +E L E + E NER LE + + L+
Sbjct: 5905 KSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELK 5964
Query: 788 KRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILTDKAK 639
K + E+ H E T K+ + NE A+ Q K + E+ E IS T+ +
Sbjct: 5965 K---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVE 6020
Query: 638 KLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 489
+++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 6021 NKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 6067
Score = 94.7 bits (234), Expect = 3e-16
Identities = 125/616 (20%), Positives = 275/616 (44%), Gaps = 31/616 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGD-------FEAAIATLNDELLNEKDDKKCIVNDRNIVEA 2139
S+ + ++ K+ L+ + D FE I + EL E ++ I + +E
Sbjct: 2366 SLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAEN---IERKKKELEI 2422
Query: 2138 DKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDE-- 1965
K A+ + E + +E D+ + + AD +E + S ++ E
Sbjct: 2423 QKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEES 2482
Query: 1964 -LLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1800
+ EKD K N++N+ L A + L+ + A++E K L + ++R + + I K
Sbjct: 2483 YVKKEKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITK 2542
Query: 1799 KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1620
+ +R+++++ + +++ D+ + ++E + IL+ EL+K
Sbjct: 2543 EK--QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEK 2588
Query: 1619 EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMK 1440
K+ KT L ++ A + K + + + L L ++E E E+ ++ +
Sbjct: 2589 IKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDR 2642
Query: 1439 AIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD 1260
EE + K ++ K + + + E+ L + +R S+ DT++ +L K K +
Sbjct: 2643 RNNEEMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTE 2700
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK 1080
L + + E Q + + +E I + L++ + +K+ LEK E +
Sbjct: 2701 MKDLEK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKE 2753
Query: 1079 NASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSD 900
A ++ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E +
Sbjct: 2754 KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 899 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDD 726
+E + ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D+
Sbjct: 2814 IE----QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDE 2866
Query: 725 DYN--------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDL 579
+ N E+++ TL+K +L++ + + D K+L + I L+E+ + +E L
Sbjct: 2867 EANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREIL 2926
Query: 578 NK----ESKEKQDLEK 543
+ SK+K+DLEK
Sbjct: 2927 EQLKLTLSKQKEDLEK 2942
Score = 94.4 bits (233), Expect = 4e-16
Identities = 139/601 (23%), Positives = 252/601 (41%), Gaps = 10/601 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR-------NIVEADKQAL 2124
+N +E K+ L+N + E + +L E N +D+K + R N + +++ L
Sbjct: 9310 KNQIEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDL 9369
Query: 2123 ENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVF--EAAIATLNDELLNEK 1950
EN + E + +E + ++ I + D + +S+ ++ E I +ELL K
Sbjct: 9370 ENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMK 9429
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL 1770
+ + + +E Q L+ DLE AK E++R++D II + ++ ++
Sbjct: 9430 VE---MGRTKEEIEKESQRLQDATIDLENAKA----EIQRQEDKFEDIIDIKIQEKEREI 9482
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1590
K Q D+E + V +LE+ + + + Q+ +D K L K
Sbjct: 9483 KI---QLDKETKRLS------------EEIELKVKDLEMEMADMKRQKQEIEDTKGLLEK 9527
Query: 1589 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ K+ + + LE + L RE+++ ER+ NL +K + E+LRKE
Sbjct: 9528 E-------KQELKQEKKELEDQMMDLT----REKQETEEERN--NLMALKN-QLEDLRKE 9573
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ EK LEK+ +E + ++++ + K +K +L +
Sbjct: 9574 NE-----------IVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRFE 9622
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
E +KQ E + + + D L R+L + K LEK + N+E
Sbjct: 9623 TEQQKQMLEISTTKMMEEKNEMAD-LSRELQKA---KDELEK---------IAYKTNKER 9669
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 870
HE E +++A ELH + + ++ + Q+++ K + +E ++
Sbjct: 9670 HEVE---QMQA-------ELHSQ----------IQAIEQQGQIMQDKQNHLEEKELSIQR 9709
Query: 869 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKK 690
+ ++ N F E++ L V + KR DLE DIE+ K N + + L+K
Sbjct: 9710 KEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEK 9765
Query: 689 RISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLE 513
SELE D+ IW + L E L + KEK+ LEK +EL SK E
Sbjct: 9766 IRSELENE-----------KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKRE 9814
Query: 512 K 510
+
Sbjct: 9815 Q 9815
Score = 94.4 bits (233), Expect = 4e-16
Identities = 135/648 (20%), Positives = 285/648 (43%), Gaps = 52/648 (8%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVE--------- 2142
I +RN LE K L + E + L+ ++ +K I ++ IVE
Sbjct: 10121 IEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQ 10180
Query: 2141 -------ADKQALENK-VADFEATIATLNDELLNEKDDKKCIVEADK------QALESKV 2004
++ ALE + + D + +A EL N+ + + + EA K + E+ +
Sbjct: 10181 RNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHL 10240
Query: 2003 SVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN---DELE 1833
+ I ++ +E +K+D + I N+ KQ L+ K LE + +N + +
Sbjct: 10241 QRDKKEIKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQ 10297
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1653
++ D+ +A ++K ++ +++ K +R +++N I ++
Sbjct: 10298 QRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHE---INQKIE 10354
Query: 1652 NILILHEELQKEKDDKTAL-IKDLVAAEPGKRTVNEIV---SHLESKSRSLKEHF-LREE 1488
+ L E++ KEK+ A+ IK + E + +E+V + ++ + + L + + E+
Sbjct: 10355 ELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQ 10414
Query: 1487 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1308
E E LE+ S + K E+E R E D K + + EK +EK+ +
Sbjct: 10415 EKEDLEKMKSEIMTQKQEMEKE-RSELDNKI------QQTDLEKHDIEKSKEIVEKLMFE 10467
Query: 1307 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL--------DLEPTIPSLNDAL 1152
+ HE +L+KE++D E +K E+ +L + I ++N+ +
Sbjct: 10468 VEEQRHEIQLQKEELD----------IERQKIADEQDLLIQNKSELQNENERIRNINEVI 10517
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 972
+++ + + + LEK +++ S+T+ + ++E K+ N +L K++D
Sbjct: 10518 KKERETLKEMEAHLEKEKEEMK----SITEETRRQKEDLE-KMSTDIKEQNQDLMKQRDL 10572
Query: 971 KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 792
E D++H E L+ ++ + + + ++ + ++ + + ER LE K
Sbjct: 10573 LEQEKEDINH---EWTQLQQRIDEFD---AQVSKQKEEDLTKQKEMKEERKSLEETK--- 10623
Query: 791 EKRVLDL--EATIHDIEMKTGKDDDYN------EAEKQTLKKRISELEEAISILTDKAKK 636
R++++ +A + DI+ + K+++ E + + L + SEL+ S + + KK
Sbjct: 10624 -ARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKK 10682
Query: 635 LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK-----LEKC 507
L D I E L++ ++ K++Q +E+ EL +K +EKC
Sbjct: 10683 LNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKC 10730
Score = 92.8 bits (229), Expect = 1e-15
Identities = 132/673 (19%), Positives = 297/673 (44%), Gaps = 31/673 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENK-------VGDFEAAIATLNDELLNE----KDDKKCIVNDR-N 2151
++N R++LE ++ + +K + +F+A ++ ++ L + K+D+K + + N
Sbjct: 10844 LMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 10903
Query: 2150 IVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN 1971
++E +A ++ + N+E E+++ + IVE +++ L S E + ++
Sbjct: 10904 VIEMKTKAEPEEIKKEKEKE---NEEEEEEEEEIRVIVETERKELYQIKSELERVRSEID 10960
Query: 1970 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE-----LERKKDDNNAI 1806
E D K I ++ LE K + + +E ++ L+++ LE+ + +
Sbjct: 10961 HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKE 11020
Query: 1805 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1626
I + L + + + D + +E D+ E N+L+ ++
Sbjct: 11021 IVEKLMVEVEEQRKDIQLQKEELDIERQKIAD-----------------EQNLLVQNKAK 11063
Query: 1625 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS---RSLKEHFLREEEDEVLERSASN 1455
+ ++++ + + + E + T+ E+ HL+ + RS+ E R +ED LE+ +++
Sbjct: 11064 LQNENERIKKVDEEIKKE--RETLREMEIHLKKEKEELRSIIEETQRRKED--LEKMSTD 11119
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR 1275
+ K L+ ++D L+E E E+ E T L++R D + E+L
Sbjct: 11120 INEQKL----HLKNQRD----LLEQ----EREEINHEMTQLQQRIDEFDAQVSKQREDLT 11167
Query: 1274 KEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCS 1095
K+++ E E++ E+T + + + +L +M EK+ ++
Sbjct: 11168 KQEM------------EEERKSLEETKARI------IEMKTKAELQEIMQEKEEEDEE-- 11207
Query: 1094 DLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLE 915
E + + +E ++ + E K S + H E K DDK+ I + + ++ + +
Sbjct: 11208 --EMRVIVEMEREELNQIKSELKRVRSEIDH--EQKKLNDDKKIIEQEKEDLEKMKSEIM 11263
Query: 914 SKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 735
++ ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 11264 TQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQ 11323
Query: 734 KDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
K D N+A+ Q +RI E++E I K K+ LK++ L + E + +
Sbjct: 11324 KIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSVIE 11379
Query: 572 ES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFS 399
E+ ++K+DLEK ++ +K + + RD L +E + W + + F
Sbjct: 11380 ETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDEFD 11432
Query: 398 RKTSPL---DITK 369
+ S D+TK
Sbjct: 11433 AQVSKQKEEDLTK 11445
Score = 92.8 bits (229), Expect = 1e-15
Identities = 128/675 (18%), Positives = 276/675 (40%), Gaps = 35/675 (5%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N R++LE ++ + +++ + I + ++ +++D + + + E K E K
Sbjct: 11129 NQRDLLEQEREEINHEMTQLQQRIDEFDAQVSKQRED----LTKQEMEEERKSLEETKAR 11184
Query: 2108 DFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEKDD 1944
E E++ EK+++ + IVE +++ L S + + ++ E DD
Sbjct: 11185 IIEMKTKAELQEIMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDD 11244
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDKRI 1779
KK I ++ LE K + + +E ++ L++ +LER +N+ I + L ++
Sbjct: 11245 KKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKV 11304
Query: 1778 SDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTA 1599
+ + D + +E D+ E QK D++
Sbjct: 11305 EEQRKDIRLQKEELDI---------------------------------ERQKIADEQGL 11331
Query: 1598 LIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
++++ + + E+ ++ + +LKE E L
Sbjct: 11332 VVQNKAKLQNENERIKEMDEEIKKEKETLKE------------------------MEAHL 11367
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---DAIHEE-----------E 1281
RKEK+ +++E E +K+ LEK + N D M D + +E +
Sbjct: 11368 RKEKEEMRSVIE--ETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQ 11425
Query: 1280 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1101
R ++ D + E +K+ E+ E I + + + +++ EK+ E+
Sbjct: 11426 QRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEE- 11484
Query: 1100 CSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV 921
E A + +E + +I+ +LE + E K DDK+ I + + ++ +
Sbjct: 11485 ----EVMRAKVEMKKEELD-QIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSE 11539
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
+ + ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 11540 IMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIE 11599
Query: 740 TGKDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 579
K D N+A+ Q +RI E++E I K K+ LK++ L + E +
Sbjct: 11600 RQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSV 11655
Query: 578 NKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQG 405
+E+ ++K+DLEK ++ +K + + RD L +E + W + +
Sbjct: 11656 IEETQRRQKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDE 11708
Query: 404 FSRKTSPL---DITK 369
F + S D+TK
Sbjct: 11709 FDAQVSKQKEEDLTK 11723
Score = 91.7 bits (226), Expect = 3e-15
Identities = 140/737 (18%), Positives = 310/737 (42%), Gaps = 97/737 (13%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ +V+++ +L + L+NK + D+ +++ +
Sbjct: 10194 ERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEE 10253
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N + K+ K + +R + + ++ +F+A + +E
Sbjct: 10254 TSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEE 10313
Query: 2072 -LLNEK---DDKKCIVEADKQALESK---------VSVFEAAIATLNDELLNEKDDKKCI 1932
L N+K +++KC+ E + + +E K ++ + TL ++++ EK+ + +
Sbjct: 10314 DLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAM 10373
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADA 1758
L+ ++ L+ ++L KT ++ E ++ DD I K+ L+K S++
Sbjct: 10374 TIK---LKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10430
Query: 1757 PQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD------KTA 1599
+ ++E +++ I +IV L + E+Q +K++ K A
Sbjct: 10431 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIA 10490
Query: 1598 LIKDLVAAEPGK--------RTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIM 1443
+DL+ + R +NE++ + ++ H +E+E+ M
Sbjct: 10491 DEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEKEE------------M 10538
Query: 1442 KAIREEELRKEKDGKSA----------LVENGEGCEAEKQGL--EKTVLERRASNLDTM- 1302
K+I EE R+++D + L++ + E EK+ + E T L++R D
Sbjct: 10539 KSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQV 10598
Query: 1301 ------DAIHEEELRKEKVD----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
D ++E+++E+ K+ + E E E EK + E + +
Sbjct: 10599 SKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 10658
Query: 1151 QRDLDRVMAE-------------------------KQALEKRCSDLEAKNASLTDNQEGH 1047
++LDR+ +E KQ LEK S++ + + + +
Sbjct: 10659 GKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSEL 10718
Query: 1046 EAEIERK-LEASNLTHNDELHKE-----KDDKESIMNDLDHVKAERQVLESKVSDMETTY 885
E +I++ +E ++ ++ E+ ++ ++ K I + + ERQ + + +
Sbjct: 10719 ENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 10778
Query: 884 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------D 723
S L NE ++ + NE ER+ L+ ++ LEK+ ++++ E + K+D D
Sbjct: 10779 SELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSE--ETRRLKEDLEKMSTD 10836
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQD-- 552
N+ K + +R LE+ + K K+L + I+ + ++V++ +E DL KE K+D
Sbjct: 10837 VNKQNKDLMNQR-DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRK 10895
Query: 551 ----LEKRVLELTSKLE 513
+ V+E+ +K E
Sbjct: 10896 SLEETKANVIEMKTKAE 10912
Score = 91.3 bits (225), Expect = 4e-15
Identities = 146/692 (21%), Positives = 284/692 (41%), Gaps = 60/692 (8%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQAL---ENK 2241
+R LE LE K + + I +NILE K L + +
Sbjct: 13497 ERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQ 13556
Query: 2240 VGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNE 2061
V + + T+ + +E ++ +C+ RN +E +K+++ ++++ + I L E+ +E
Sbjct: 13557 VQQQKHEMETIRKTMKSEMENLECL---RNELEDEKKSMLSRLSMEKHEIDKLKTEIQSE 13613
Query: 2060 KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYK 1881
K+ +E +K+ L+ E+ L++ + DK I +++ LE K L+ K
Sbjct: 13614 KES----IEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRK 13669
Query: 1880 VADLE-----AAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIX 1716
L+ A + T + K D++ ++ L +D++ A + E D+ L
Sbjct: 13670 AEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQA--KILESDVQLLQT 13727
Query: 1715 XXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNE 1548
+ +LE N L L +EL+KEK +I D+ + +
Sbjct: 13728 EKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------D 13779
Query: 1547 IVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGE 1374
V+ L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 13780 AVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENM 13838
Query: 1373 GCEAEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTE 1242
+ + ++ + E R D + DA+ + +EL K D E
Sbjct: 13839 KMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKE 13898
Query: 1241 NGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA---- 1083
+ E E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 13899 HVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADD 13958
Query: 1082 --------KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH 942
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 13959 IKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQ 14018
Query: 941 ---------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGL 792
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +
Sbjct: 14019 KEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 14078
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 612
E +EKQ++++ +EL K+L +++ +
Sbjct: 14079 E-------------------------SEKQSIERERAEL-----------KRLKEEVEVQ 14102
Query: 611 LSEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
E T LQ+D N KEK+ LE T ++
Sbjct: 14103 -HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 14133
Score = 90.1 bits (222), Expect = 8e-15
Identities = 141/644 (21%), Positives = 275/644 (42%), Gaps = 49/644 (7%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN- 2118
I NDR E L+N+ D E + + DE N + K+ + +DR+ +E ++ LE
Sbjct: 2638 IDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKT 2697
Query: 2117 --KVADFEATIATLND-------ELLNEKD---DKKCIVEADKQALESKVSVFEAAIATL 1974
++ D E + + + E+ E++ K + K+ LE + FE A +
Sbjct: 2698 KTEMKDLEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1973 N-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERK--KDDNNAI- 1806
+ E L E+ +K+ I D+ + ++ E + L K N+EL+++ +D+ + I
Sbjct: 2758 SLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE 2815
Query: 1805 -IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1638
IK L K D + ++D E+D ++ + + E N+ +L
Sbjct: 2816 QIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVL 2873
Query: 1637 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSA 1461
+ L+ ++D L K+ + + ++ LES++R + ++E E+LE+
Sbjct: 2874 KQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1460 SNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1290
L+ K E+E KEK S E E ++E++G+ KT R MD
Sbjct: 2931 LTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIKKEMD--- 2981
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL 1110
EL++ +++ EN E +KQ ++ + D++ K L
Sbjct: 2982 --ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKIEQIKAEL 3018
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDKESIMNDL 948
+K D E + + ++ +E + ++ +E S DE + K+ + +D
Sbjct: 3019 QKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDR 3078
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
D ++ ER LE ++M L ++++Q ER+ LE +K L K+ DLE
Sbjct: 3079 DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLE 3138
Query: 767 ATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL------TDKAK 639
E + +D ++E++ +K+ + ELE+ L + K
Sbjct: 3139 KERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQK 3198
Query: 638 KLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 510
K+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3199 KIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 89.0 bits (219), Expect = 2e-14
Identities = 139/671 (20%), Positives = 284/671 (42%), Gaps = 55/671 (8%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R I+E ++ L + + + ++ E DDKK I ++ +E K + +
Sbjct: 11210 RVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQM 11269
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALES---KVSVFEAAIATLNDELLNEK----DD 1944
E + L D + + D ++ +E K+ ++ KV I +EL E+ D+
Sbjct: 11270 EEERSEL-DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADE 11328
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISD 1773
+ +V ++ L+ + ++ +++ K TL + L ++K++ ++I++ ++ D
Sbjct: 11329 QGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKED 11388
Query: 1772 LK---ADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
L+ D +++Q+ L+ + L+ I ++ K+K++
Sbjct: 11389 LEKMSTDVNKQNQD-----LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED- 11442
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE---EEDEV-----------LERS 1464
L K E K + +E K+++ E +E EE+EV L++
Sbjct: 11443 -LTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQI 11501
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIH 1290
S L +++ + E +K D K + + E E K + ++ +E S LD + I
Sbjct: 11502 KSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELD--NKIK 11559
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDLEPT--------IPSLNDALQR 1146
+ +L + ++ S E E+Q + K LD+E + LQ
Sbjct: 11560 QTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQN 11619
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ +R+ + ++K L+ A L +E E+ +E + ++L K D
Sbjct: 11620 ENERIKEMDEEIKKEKETLKEMEAHLRKEKE----EMRSVIEETQRRQKEDLEKMSTDVN 11675
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
+ +MN D +K ER+ + K + +LQQ++D+ +A ++++ + KQ
Sbjct: 11676 KQNQDLMNQRDLLKQEREEINHKWT-----------QLQQRIDEFDAQVSKQKEEDLTKQ 11724
Query: 797 G-LEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD 624
+E+ LE T I IEMKT + + + EK+ E EE + + K+ L
Sbjct: 11725 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE------KEEEEVMRAKVEMKKEELDQ 11778
Query: 623 INIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I L SE+ Q+ LN + K EK+DLEK E+ + ++ + + I++
Sbjct: 11779 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 11838
Query: 467 AWMSDCMVPDN 435
++ C + ++
Sbjct: 11839 TYIEKCDIENS 11849
Score = 88.2 bits (217), Expect = 3e-14
Identities = 139/691 (20%), Positives = 288/691 (41%), Gaps = 34/691 (4%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
+R ++E Q L + + L E+ K K+ I ++N ++ K L+ + D
Sbjct: 3433 ERGLIEERTQMLNTYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQREADD 3492
Query: 2105 FEA----------TIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLN 1956
+ ++ + + L EKDD + E K+ + + E+A+A + E N
Sbjct: 3493 IKKLKEKTRNERQSLEKMAENLEKEKDDLAHLAEDTKRKDDEMKVLHESALADIQKEKCN 3552
Query: 1955 EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKK---ALDK 1785
+ ++ + ++++ K+ + + L+ + +N + + + D +II+ A+ K
Sbjct: 3553 LEQMRESMFKQNEMIDSEKKKMILREDKLQQMQAEINRQ-QTEMDTKKSIIENERAAMTK 3611
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
+ DL + ++ ++ +E+ + + E + + D+
Sbjct: 3612 KNQDLMTELTKQSED--------------------------VEIQMKEVLTEKELLESDR 3645
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE-HFLREEEDEVLERSASNLAIMKAIRE 1428
L KD+ + + + +ES S SLK+ L E E EVL++ ++L
Sbjct: 3646 KLLKKDV-------ENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQG----EA 3694
Query: 1427 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1248
EE+ K K +E + E+Q +E+ + + D ++ + EE RK+ V L
Sbjct: 3695 EEIEKIK------LET----QHERQRVEEMTAQIQKER-DKINNLIEETNRKDMV----L 3739
Query: 1247 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1068
E D+E I S+ Q D D + EK LEK S+L L
Sbjct: 3740 NEKNR--------------DIEEKIKSI----QSDKDMLEKEKHNLEKTRSELYKVKEDL 3781
Query: 1067 TDNQEGHEAEIERK------------LEASNLTHNDELHKEKDD-----KESIMNDLDHV 939
+E AEI+++ +E + H +E K+K D K I N +
Sbjct: 3782 EKQKENTLAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQEL 3841
Query: 938 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 759
+ E++++ S+++ S L+ + D E NER L+ K+ +E++ ++E
Sbjct: 3842 EKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEKER 3901
Query: 758 HDIEMK-TGKDDDYN--EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 588
+++ D+D + +KQ +++ ++LE+ L +A ++ K +E L+
Sbjct: 3902 DNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNERQSLE 3961
Query: 587 EDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQ 408
+ KE++DL + E T + ++ + D + ++ M+D + E++ +
Sbjct: 3962 KMTKALIKEREDL-VHLAEYTKREKEML----DEMQVANKSSMADLQREKRIL--EEMRE 4014
Query: 407 GFSRKTSPLDITKTCDAVDISEDSTTNIQVD 315
S++T DI + + ED +Q +
Sbjct: 4015 NISKQTE--DIENEKEKSKLREDELKKLQTE 4043
Score = 88.2 bits (217), Expect = 3e-14
Identities = 131/622 (21%), Positives = 266/622 (42%), Gaps = 27/622 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVG-------DFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD 2136
I+ R +E + L+NK+ D E + + ++ ++ +K I + ++ +
Sbjct: 10987 IMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIE 11046
Query: 2135 KQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLN 1956
+Q K+AD + + +L NE + K + E K+ E+ + + L
Sbjct: 11047 RQ----KIADEQNLLVQNKAKLQNENERIKKVDEEIKKERET--------LREMEIHLKK 11094
Query: 1955 EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDK 1785
EK++ + I+ + + K+ LE D+ K L ++ LE+++++ N + + L +
Sbjct: 11095 EKEELRSIIEET---QRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQ-LQQ 11150
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
RI + DA Q +D+ I + + + +E ++E +++
Sbjct: 11151 RIDEF--DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEE 11208
Query: 1604 TALIKDLVAAEPG--KRTVNEIVSHLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAI 1434
+I ++ E K + + S ++ + + L + + E+E E LE+ S + +
Sbjct: 11209 MRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQ 11268
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
EEE R E D K +++T LER +++ I ++ + K + +
Sbjct: 11269 MEEE-RSELDNK----------------IKQTDLERH--DIENSKEIVQKLMVKVEEQRK 11309
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 1074
+ E + E+Q + D + + LQ + +R+ + ++K L+ A
Sbjct: 11310 DIRLQKEELDIERQ----KIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEA 11365
Query: 1073 SLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KESIMNDLDHVKAERQVLESKV 906
L +E E+ +E + ++L K D + +MN D +K ER+ + K
Sbjct: 11366 HLRKEKE----EMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKW 11421
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG-LEKRVLDLEAT-IHDIEMKTGK 732
+ +LQQ++D+ +A ++++ + KQ +E+ LE T I IEMKT
Sbjct: 11422 T-----------QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKT 11470
Query: 731 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKESK 564
+ + + EK+ E EE + + K+ L I L SE+ Q+ LN + K
Sbjct: 11471 EPEKIKKEKE------KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKK 11524
Query: 563 ----EKQDLEKRVLELTSKLEK 510
EK+DLEK E+ + ++
Sbjct: 11525 MIEQEKEDLEKMKSEIMKQRQQ 11546
Score = 87.8 bits (216), Expect = 4e-14
Identities = 143/649 (22%), Positives = 278/649 (42%), Gaps = 45/649 (6%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEA---AIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N+++ ++ E K + + A+ +N EL + + K + + EAD Q +NK
Sbjct: 13478 NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTE 13537
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
+ + + EL EK V+ K +E+ ++ + L + L NE +D+K +
Sbjct: 13538 ELKNILEREKSELYQEKAQ----VQQQKHEMETIRKTMKSEMENL-ECLRNELEDEKKSM 13592
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDKRISDLKADA 1758
R L K ++ ++++ K ++ +E L++ KD+N + + LD I + D
Sbjct: 13593 LSR--LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENES-KRTQLDNTIEKMNMDK 13649
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
+E D +I ++L+ L EE++K + + +D
Sbjct: 13650 LSIQREKD----------------SLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKI 13693
Query: 1577 AEPGKRTVNEIVS---HLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ + E+ S +E +++ L+ L + E E+LE+S + +++ E+L K+
Sbjct: 13694 LDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLR----EDLEKQ 13749
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ ++ EK LE+ + + D + ++ E K+ K+ TE E
Sbjct: 13750 RKRNDLTLQE---LRKEKMALEQMITD-ITKEKDAVASLQNEVSLKQHELKNKETELDE- 13804
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+++ + + LE S N Q+++D + E K +DLE+ L + +
Sbjct: 13805 ---QRKEMDDLRMQLEMRQNSTNKQ-QQEVDVFIVENM---KMRNDLESMKTLLDEERRQ 13857
Query: 1049 HEAEIERKLEASNLTH---------NDELHKEKDDKESIMNDLDHVKAERQ---VLESKV 906
+ I+ + N+ H DEL K D I + +HV+ ER+ VL ++
Sbjct: 13858 LQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD---IKTEKEHVEKEREEIDVLNKEI 13914
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE--MKTGK 732
+ +LN E+ E F E G A + LE+ DL A DI+ ++T K
Sbjct: 13915 IKSKEELQSLNLEI-------EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEK 13967
Query: 731 DDDYNEAEKQT-------LKKRISELEEAIS-------------ILTDKAKKLLKDI-NI 615
+ EK+T L+K+ +ELEE + I+ DK +K ++DI +
Sbjct: 13968 QMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTV 14027
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
SE L+++ ++ +K L ++V +LE+ + RD + K+
Sbjct: 14028 IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKK 14076
Score = 87.4 bits (215), Expect = 5e-14
Identities = 127/646 (19%), Positives = 279/646 (43%), Gaps = 58/646 (8%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
++ KQ ++ K A+ L K+ ++ I ++ +E +K ++ + +
Sbjct: 9830 IQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKV 9889
Query: 2093 IATLNDELLNEKDDKKCIVEAD----KQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
+ E + + +K I EAD K+ E+ E + +++ N ++ K +
Sbjct: 9890 L-----EEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQ 9944
Query: 1925 DRNILEAAKQALEYKVADL-----------EAAKTTLNDELERKKDDNNAIIKKA--LDK 1785
+R ++ KQ L+ + DL E +K +L++E + + N I+++ L+K
Sbjct: 9945 ERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEK 10004
Query: 1784 RISDL-----KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE--- 1629
D+ K D Q + +++ A+ K LE ++ ++EE
Sbjct: 10005 EKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGD 10064
Query: 1628 ---LQKEKDDKTALIKDL-VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE-VLERS 1464
++ + + + I+++ V A+ ++ +++I S LE + + + D ++E+
Sbjct: 10065 LEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKE 10124
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDTMD--- 1299
++L MK+ + ++ +D +S L + + EK +EK ++ER + ++
Sbjct: 10125 RNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDF 10184
Query: 1298 AIHEEELRKEK---VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-------Q 1149
+ +EEL E+ VD+ L CE E Q + + ++E + + + L Q
Sbjct: 10185 KLKKEELALERQNIVDEKYLLAQ---CETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 10241
Query: 1148 RD-------LDRVMAEKQALEKRCSDLEAKNASLT---DNQEGHEAEIERKLEASNLTHN 999
RD ++ +K+ LEK + + + L D E EI K +
Sbjct: 10242 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 10301
Query: 998 DELHKEKDDKESIMNDLDHVKAERQVLES---KVSDMETTYSTLNNELQQKMDDNEAFLN 828
+ + + KE + + ++ ER+ LE K+ +M+T ++E+ QK+++
Sbjct: 10302 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEE------ 10355
Query: 827 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 648
L+ +++ + K EA ++M E++ L + SEL + +
Sbjct: 10356 ----LQTLQEQIMKEKEKAEAMTIKLKM-----------EREDLDQIKSELVREKTEVDH 10400
Query: 647 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
+ KKL DI + E +L++ ++ +KQ++EK EL +K+++
Sbjct: 10401 EQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 10446
Score = 85.5 bits (210), Expect = 2e-13
Identities = 144/713 (20%), Positives = 299/713 (41%), Gaps = 118/713 (16%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
++N R++L+ ++ + +K + I + ++ +K++ + + + E K E K
Sbjct: 11403 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED--LTKQKKMEEERKSLEETK 11460
Query: 2114 VADFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEK 1950
+ E T +++ EK+ + + VE K+ L+ S E + ++ E
Sbjct: 11461 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11520
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDK 1785
DDKK I ++ LE K + + +E ++ L++ +LER +N+ I + L
Sbjct: 11521 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMV 11580
Query: 1784 RISDLKADAPQRDQE---------DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
+ + + D + +E D+ ++ ++ ++ L E
Sbjct: 11581 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKE 11640
Query: 1631 ---ELQKEKDDKTALIK----------------------DLVAAEPGKRTVNEIVSHL-- 1533
L+KEK++ ++I+ DL+ + E ++H
Sbjct: 11641 MEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWT 11700
Query: 1532 --------------ESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGK 1398
+ K L + EEE + LE + + MK E E+++KEK+ +
Sbjct: 11701 QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE 11760
Query: 1397 SALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEE--------LRKEKVD---- 1260
V + E +K+ L+ K+ LER S +D HE++ + +EK D
Sbjct: 11761 EEEVMRAK-VEMKKEELDQIKSQLERVRSEID-----HEQKKLNDDKKMIEQEKEDLEKM 11814
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDL---EPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
KS + + + E E+ E + + I + + +Q+ + V +K ++ + +L
Sbjct: 11815 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 11874
Query: 1088 EAKNASLTDNQE---GHEAEIER------------KLEASNLTHNDE-LHKEKDDKESIM 957
+ + + D Q+ +++E++ K E L + L KEK++ +SI
Sbjct: 11875 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 11934
Query: 956 N-------DLD----HVKAERQVLESKVSDMETTYSTLNN---ELQQKMDDNEAFLNER- 822
DL+ H+ ++Q L S+ +E +N+ +LQQ++D+ +A ++++
Sbjct: 11935 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 11994
Query: 821 -DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDK 645
+ L K+ E R E + +EMKT + + + EK+ E E+ + + +
Sbjct: 11995 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEK-----EEEEQEMRVKVEM 12049
Query: 644 AKKLLKDINIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEK 510
+K ++ I L SE+ Q+ LN + K EK+DLEK E+ + ++
Sbjct: 12050 ERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQ 12102
Score = 85.1 bits (209), Expect = 3e-13
Identities = 128/613 (20%), Positives = 259/613 (42%), Gaps = 34/613 (5%)
Frame = -2
Query: 2261 KQALENKVGD-FEAAIATLNDELLNEKDDKKCIVN-DRNIVEADKQALENKVADFEATIA 2088
KQ + K+ D + + + D + + K ++ +++ +E K ++ ++ +FE +
Sbjct: 14581 KQPIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNME 14640
Query: 2087 -TLND---------ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
TL + +LL++KDD ++ + +E+ F+ IA L + K DK+
Sbjct: 14641 ETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE 14700
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAA------------KTTLNDELERKKDDNNAIIKKA 1794
I N+ L+ +Q E + + + KT L D E+KK D ++ +K
Sbjct: 14701 NIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLK-- 14758
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
++D AD+ + D E + L + V L EEL E
Sbjct: 14759 ----LTD--ADSAKTDGEREAQTL-----------ETKVQDVLQLTDYTTQDQEELHDEM 14801
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAI 1434
++K +I +L A+ + + L+ + RS +E + E LER ++L
Sbjct: 14802 ENKMKIILELNEAK-------KDLQKLKEECRSAEEE--KSVIMESLERRRNSL------ 14846
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLERRASNLDTMDAIHEEELRKEKVDK 1257
E+++ E + +++ + E Q +E K ++ R+ + ++ ++
Sbjct: 14847 --EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQGQEATETT 14904
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPS----LNDALQRDLDRVMAEKQALEKRCSDL 1089
+T+ E + K+ + TV LE T+ S + D+L ++++ V K ++ L
Sbjct: 14905 GHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQL 14964
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD----HVKAERQV 921
E + + E E +E +E + + ++L + DKE + N LD ++ +
Sbjct: 14965 EQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKLLQLTHDKEDLSNTLDKKNKEIENNTET 15023
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
K++ +ETT + + K+ +E +L L+ T + E++
Sbjct: 15024 SLKKIAQLETTIVLMKKD---------------------KENIENELLQLKQTEQEREIQ 15062
Query: 740 TGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 564
G DD NE EK K +ELE+ + KK +D ++ L++ + D +E++
Sbjct: 15063 RGTDDTSNEREKYDEKVTYKTELED-----NKEKKKPDRDSSLKLTDADSAKTDGEREAQ 15117
Query: 563 EKQDLEKRVLELT 525
+ + VL+LT
Sbjct: 15118 TLETKVQDVLQLT 15130
Score = 84.0 bits (206), Expect = 6e-13
Identities = 125/589 (21%), Positives = 252/589 (42%), Gaps = 18/589 (3%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDEL-LNEKDDKKCIVNDRNIVEADKQALENKVADFE- 2100
+E KQ ++N+ + A L +E NE+ +++ + N + A + + DFE
Sbjct: 7071 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQKVN-QQKQATAFQMEKTDFER 7129
Query: 2099 --ATIATLNDELLNEKD-DKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
I N EL ++++ +KK I E K+ TL + N + I
Sbjct: 7130 IKTEIDQANKELADQQEKNKKTITEMQKER------------ETLEEMRANISKQVETIT 7177
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA-LDKRISDLKADAPQ 1752
N+ L + + L D+ L + E + N +++ LD+R SD+ D Q
Sbjct: 7178 NENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQ 7229
Query: 1751 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAE 1572
++ +D M+ ++N+E L + + + K D +L + A E
Sbjct: 7230 KEVDDLMD--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACE 7275
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
+ +NE +E + L ++ ++D++ ++R NL + K + E ++ + K
Sbjct: 7276 QLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKI 7335
Query: 1394 ALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGE 1233
+L G + +EK E+ ++E A+ LD + E + +E++D++
Sbjct: 7336 SLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKT 7395
Query: 1232 GCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE 1053
+ EKT DL+ T +N D + + ++ L K
Sbjct: 7396 YYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK----------------- 7432
Query: 1052 GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 873
E E +++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + +
Sbjct: 7433 --EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMM 7487
Query: 872 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ--- 702
E + D E NE+D L+ ++ ++K + +L+ E + + N+ +Q
Sbjct: 7488 KEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTE 7541
Query: 701 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 561
+K + L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7542 EIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7590
Score = 84.0 bits (206), Expect = 6e-13
Identities = 115/623 (18%), Positives = 262/623 (42%), Gaps = 6/623 (0%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
+ L E+ ++ K ++++ I +++ Q L + + L E+ N K DK +
Sbjct: 8729 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNL 8788
Query: 2039 VEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA 1860
E K LE K E+ L E + KK I ++ +E +++ +E ++ + E
Sbjct: 8789 -EKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVK 8847
Query: 1859 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 1680
T ++++ K++ + ++ L K+ + + D + M L
Sbjct: 8848 GFT---DVQKYKEELQIVTEELLTKKRN---LEQLNSDVQHLMQTLEEVDIQYIKKKAEL 8901
Query: 1679 XKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF 1500
I S ++ IL E+ +K+ ++ +I+++ + ++N + KE+
Sbjct: 8902 EHITSEIQKREQIL-EKQKKKLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENL 8960
Query: 1499 LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRA 1320
RE+++ L R EL++++D VE+ ++ K ++ +
Sbjct: 8961 RREKQETELFRG-------------ELQRQRDE----VESSRQALIMEKDQFKLKIDHQR 9003
Query: 1319 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1140
+ + A +E R E ++ + + E+ + +E + + + L ++
Sbjct: 9004 NEMSA--AFEKEHKRLENMENDLENQRAKLAESLNDAAK-----MEQKLQQMKNELNKEK 9056
Query: 1139 DRVMAEKQALEKRCSDLEAKNASLTDN----QEGHEAEIERKLEASNLTHNDELHKEKDD 972
++V KQ ++ +E + + ++GHE ++++K E + D+L ++ +
Sbjct: 9057 EQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANS 9110
Query: 971 KESIMNDLD-HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG 795
+ + DL ++ +RQ +E ++MET +L+ ++ DD N+RD E
Sbjct: 9111 ESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTH 9170
Query: 794 LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 615
LE + +L D+E K + + +E K+ ++ + LE + K + K++
Sbjct: 9171 LELKREELVRETEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMEN 9230
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPD 438
SE +L ++ +LE RV +E L++ + + E MS+ + +
Sbjct: 9231 VHSERQKLLLLQGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTE 9288
Query: 437 NWVPFEDLVQGFSRKTSPLDITK 369
+ L++ R+ L+I+K
Sbjct: 9289 Q-NEYRKLIEELQREKEQLEISK 9310
Score = 84.0 bits (206), Expect = 6e-13
Identities = 140/656 (21%), Positives = 289/656 (44%), Gaps = 72/656 (10%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
IA + D+LL EK+D + N + + +++++ D + + N +LL K +
Sbjct: 13332 IADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTE---- 13387
Query: 2039 VEADKQALESKVSVFEAAIATLNDELL---NEKDDKKCIVNDRNILEA-AKQALEYKVAD 1872
++ ALE + + +N ++ E++ + ++ + E A+ ++ + D
Sbjct: 13388 IQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 13447
Query: 1871 LEAAKTTL----------NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMN 1728
+E+ K L N EL+ + ++ +IKK ++ + K + QR+++ + MN
Sbjct: 13448 IESVKVRLVTESNQIDKMNSELKTRSEELENLIKK--QQKEFETKENEMQRERKALEKMN 13505
Query: 1727 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG-----K 1563
A + + N + + +LQKEK +KT +K+++ E K
Sbjct: 13506 AELERKSTE----------LKNKIEKVTVWEADLQKEK-NKTEELKNILEREKSELYQEK 13554
Query: 1562 RTVNEIVSHLESKSRSLKEHF-----LREEEDEVLERSASNLAIMK-------------- 1440
V + +E+ +++K LR E ++ + S L++ K
Sbjct: 13555 AQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQSEK 13614
Query: 1439 -AIREE-----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA------ 1296
+I EE +L+ E + K ++N EK ++K ++R +L+ + A
Sbjct: 13615 ESIEEEKKTLKQLKDENESKRTQLDN----TIEKMNMDKLSIQREKDSLEEIKADLQRKA 13670
Query: 1295 -IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1119
+EE+RK S ++++ + + +++ E+ + + I L+ D+ + EK
Sbjct: 13671 EKLDEEMRKAVQITSQISQDAKILDDDRE-KEEELRSMRADIERQAKILESDVQLLQTEK 13729
Query: 1118 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
+ LEK S T+N E ++E++ + ++LT EL KEK E ++ D+
Sbjct: 13730 EILEK----------SKTENDLLRE-DLEKQRKRNDLT-LQELRKEKMALEQMITDITKE 13777
Query: 938 KAERQVLESKVSDMETTYSTLNNEL---QQKMDDNEAFLNER-DGLEAVKQGLEKRVLDL 771
K L+++VS + EL +++MDD L R + +Q ++ +++
Sbjct: 13778 KDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVEN 13837
Query: 770 EATIHDIE-MKTGKDDDYNEAEKQTLKKRISELEEAISIL----------TDKAKKLLKD 624
+D+E MKT D+ E++ L+ I E+ ++L TD+ +K D
Sbjct: 13838 MKMRNDLESMKTLLDE-----ERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 13892
Query: 623 INIWLSEVTELQED---LNKE-SKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I V + +E+ LNKE K K++L+ LE+ ++ I G R + ++++
Sbjct: 13893 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEI-EMFKQEIAGKRAQIESLEQ 13947
Score = 83.6 bits (205), Expect = 8e-13
Identities = 137/630 (21%), Positives = 251/630 (39%), Gaps = 35/630 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN 2118
++V + E KQ +E++ E A L E + + ++ I NDR E L+N
Sbjct: 2792 NVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQN 2851
Query: 2117 KVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ D E + + DE N + KQ LES E L KD +K
Sbjct: 2852 EKKDIETSTDRIRDEEAN--------LRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEK 2903
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+ + E ++ + LE K TL+ + E + + + K+ D IS +
Sbjct: 2904 QLESQNRQHEIQLAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKAD--ISLREELQ 2961
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNIL---ILHEELQKEKDDKTALIKD 1587
Q ++E + +V LE N L I+ +E K + K L K+
Sbjct: 2962 EQSEREGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKE 3021
Query: 1586 LVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSASNLAIMKAIREEELRKE 1410
E +R + E R+ +E ++ + E + +E S IR+EE E
Sbjct: 3022 AEDTEKQRRDI-------EKDRRNNEEMVIKLQNEKKDIETSTDR------IRDEEANLE 3068
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSA------- 1251
K L + + E E+ LEKT E I + E++ ++ K
Sbjct: 3069 VQ-KQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLK 3127
Query: 1250 --LTENGEGCEAEKQGPEKTVLDLEPT-----------IPSLNDALQRDLDRVMAEKQAL 1110
L++ E E E+ EK D+ + I + +++++D + +Q L
Sbjct: 3128 INLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNL 3187
Query: 1109 EKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
K + E + + D ++ E AE++++ E + L EL E+ + E L
Sbjct: 3188 AKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKL----ELQNERQNLEEAGTKL--- 3240
Query: 938 KAERQVLESKVSDMETTYSTLNN-----ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 774
K +R+ +ES ++ L N E+Q+K +++ + ER +E L+K V D
Sbjct: 3241 KKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTD 3295
Query: 773 LEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 603
+ D+E + ++ + N +AE Q K + L++ IS + + + E
Sbjct: 3296 IAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVE 3355
Query: 602 VTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ +LQ + ++ E + K ++ +LE
Sbjct: 3356 LEQLQALIYRQQDEIEANRKAIINEKYRLE 3385
Score = 80.1 bits (196), Expect = 9e-12
Identities = 129/633 (20%), Positives = 265/633 (41%), Gaps = 46/633 (7%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
++R ++ + ++ ++ + E L E N + KK I ++R+ +E K L+ +
Sbjct: 3161 SEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEA- 3219
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
E T L +E N ++ ++ D++ +ES L + + + +K
Sbjct: 3220 --EKTKLELQNERQN-LEEAGTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANE 3276
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA-------------IIKKALD 1788
+++ + E L+ V D+ AK L ++L +++ N ++K+ +
Sbjct: 3277 SNKQMQERVLIELKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGIS 3336
Query: 1787 KRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD 1611
++ D+ Q R +E ++ L K + N + + E+ + +
Sbjct: 3337 EQQVDIVNKTEQLRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQR 3396
Query: 1610 DKTALI----KDLVAAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAI 1446
+ ++ KD E K +E+++ L KE L EE ++L +
Sbjct: 3397 EVNQMMEYASKDRANLEKEK---SEMIAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQ 3453
Query: 1445 MKAIREEELRKEKDGKSALVENGEGCEAEKQGLE------KTVLERRASNLDTMDAIHEE 1284
+ E E+++ K K A+ E + K L+ K + E+ + +++ + E
Sbjct: 3454 KRTALEVEMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEKM-AE 3512
Query: 1283 ELRKEKVDKSALTENGEGCEAE-KQGPEKTVLDLEP---TIPSLNDALQRDLDRVMAEKQ 1116
L KEK D + L E+ + + E K E + D++ + + +++ + + + +EK+
Sbjct: 3513 NLEKEKDDLAHLAEDTKRKDDEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKK 3572
Query: 1115 ALEKRCSDLEAKNASLTDNQEGHEAE---IERKLEASNLTHND---ELHKEKDDKESIMN 954
+ R L+ A + Q + + IE + A + D EL K+ +D E M
Sbjct: 3573 KMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMTELTKQSEDVEIQMK 3632
Query: 953 DLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 774
+ V E+++LES ++ L +L D+E+ +R+ LE K+ L++ D
Sbjct: 3633 E---VLTEKELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTD 3689
Query: 773 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDIN---IWLSE 603
L+ +IE + E Q ++R+ E+ I DK L+++ N + L+E
Sbjct: 3690 LQGEAEEIEK--------IKLETQHERQRVEEMTAQIQKERDKINNLIEETNRKDMVLNE 3741
Query: 602 --------VTELQEDLNKESKEKQDLEKRVLEL 528
+ +Q D + KEK +LEK EL
Sbjct: 3742 KNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSEL 3774
Score = 79.7 bits (195), Expect = 1e-11
Identities = 110/587 (18%), Positives = 242/587 (41%), Gaps = 7/587 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
RN +EA K +EN+ + + D + K ++ + +++ + L KV
Sbjct: 13997 RNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQRE 14056
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + L ++ ++ ++ K I+E++KQ++E + A + L +E + + ++ + D
Sbjct: 14057 QEELERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEE-VEVQHERTLLQQD 14111
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR-- 1749
+N+++ K+ LE + A L +E++RK + + + K+ KR + P+
Sbjct: 14112 KNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIE 14171
Query: 1748 -----DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+EDD+ ++ + +E+ K + + +++
Sbjct: 14172 IEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEET 14231
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
VA + V ++ L S+ + +++H L LA MK I + E + K
Sbjct: 14232 VATTAKQPIVIKLEDTLTSEVQEMRDH---------LNNEIKELARMKTIMKMEKDQLKQ 14282
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE 1224
KS + E E + +E+ + E+ + + H++E +DK + E
Sbjct: 14283 AKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDK-----KNKEIE 14334
Query: 1223 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE 1044
+ K + LE TI + + + ++ KQ ++R +++ K A +T
Sbjct: 14335 NNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQER--EIQRK-ADVTST----- 14386
Query: 1043 AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL 864
E+++ +T+ EL +D KE I D D E +S +D E TL ++
Sbjct: 14387 ---EKEMYTEKVTYKTEL---EDSKEKIKPDRDST-LELTDTDSAKTDGEREAQTLETKV 14439
Query: 863 QQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI 684
Q + + +++ L + K +L+L D+ Q LK+
Sbjct: 14440 QDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDL---------------QKLKEEC 14484
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 543
EE S++ + ++ + SEV L ++++ ++ K ++++
Sbjct: 14485 RSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQ 14531
Score = 77.8 bits (190), Expect = 4e-11
Identities = 127/620 (20%), Positives = 259/620 (41%), Gaps = 70/620 (11%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQA---LESKVSVFEA 1989
D+ + A+ Q L ++ + L E+ K+ I++ D++ L+ +V
Sbjct: 1361 DQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKE----IMKRDREEIRLLKIEVQRRRR 1416
Query: 1988 AIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD-NN 1812
I ++++ E+D+ + + + + ++ LE ++ ++ ND +E+ ++D NN
Sbjct: 1417 EIEYREEKIMREQDELELM---SKMGQRQREELEERLEEVIKE----NDRVEQMREDVNN 1469
Query: 1811 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
A+ K +D+ D++ QE A++ I S + L L
Sbjct: 1470 AL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKS-YRASDLELSA 1526
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 1452
+QKE+ + K+++ E K +N+I +++ +E ++ E+E E +
Sbjct: 1527 SIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKLHEEEK-EMKTKRV 1582
Query: 1451 AIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------EKTVLERR------ 1323
++ R+ + KEK+ G A+ + KQ L EK+ LE +
Sbjct: 1583 SLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIK 1642
Query: 1322 -------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE------- 1203
AS D +I E + +++ ++ + C E+Q E
Sbjct: 1643 QVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDE 1702
Query: 1202 ------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+T D+E + L++ D + K ++K DL+ + A +
Sbjct: 1703 LSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREK 1762
Query: 1058 QEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAERQVLESKVSDMET 891
+E E+E+ + N D E K E D K ++ + ++++A+R+++E + +E
Sbjct: 1763 EEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALEN 1822
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM------KTGKD 729
L E +ER +E + L++ +LE HD++ + KD
Sbjct: 1823 MKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKD 1882
Query: 728 -DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWLSEVTELQEDLNKE 570
++ E + TL K S++ E IS L + K +++ I I ++ ++Q DLN++
Sbjct: 1883 LENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQ 1942
Query: 569 SKEKQDLEKRVLELTSKLEK 510
KE QD++ V S+L+K
Sbjct: 1943 QKEMQDIQNAVFMEKSELKK 1962
Score = 76.6 bits (187), Expect = 1e-10
Identities = 135/691 (19%), Positives = 273/691 (39%), Gaps = 100/691 (14%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R ++E K+ALEN + + + N D+++ + N ++ + + LE K D
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + T + + ++ + + E +++K V E I+ LN + +KD+
Sbjct: 1870 QQ-LQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQ---QKDE------- 1917
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
+E K ++ + DL+ +T LN + + +D NA+ K L K ++ A Q
Sbjct: 1918 ---IENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQL 1971
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAE 1572
Q DM NL+ I+ ++LQ E+D L ++L + +
Sbjct: 1972 KQVGDMMQFTQNEK-------------DNLDRERAAIIEQKLQMERDMTHLLNRELESLK 2018
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
K+ V LE SL E+ ++ LER + + + EE K +
Sbjct: 2019 LVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQ 2078
Query: 1394 ALVENGEGCE----AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK---------- 1257
L E+ E AEKQ LE +E + + M+ E + ++E VDK
Sbjct: 2079 TLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEI 2138
Query: 1256 ------------SALTENGEGC---------------EAEKQGPEKTVLDLEPTIPSLND 1158
+A+ EN + E+Q ++ V ++E +L D
Sbjct: 2139 TFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-D 2197
Query: 1157 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER----KLEASNLTHNDEL 990
+Q ++D+ E+Q +E + +LE + + L ++++ + E+ + E + N EL
Sbjct: 2198 EMQMEVDK---ERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLEL 2254
Query: 989 HKEKDDKESIMNDLD---------------------------------HVKAERQVLESK 909
E KE + +L+ ++A++ K
Sbjct: 2255 QSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKK 2314
Query: 908 VSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
++T L+++ + E+ E + +E K+ + ++ E+ + +EM+
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM 2374
Query: 728 DDYNEA----------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV------T 597
Y E ++Q +K I ++ + I + ++ K++ I V
Sbjct: 2375 KKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYML 2434
Query: 596 ELQEDLNKESK--EKQDLEKRVLELTSKLEK 510
E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2435 ETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 76.3 bits (186), Expect = 1e-10
Identities = 149/734 (20%), Positives = 298/734 (40%), Gaps = 87/734 (11%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDR----NILEAAKQALEN 2244
+++ LE K ++ ++ +FE + +++D+ N L+ + +EN
Sbjct: 14617 EKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIEN 14676
Query: 2243 KVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALE---------NKVADFEATI 2091
F+ IA L + K DK+ I N+ ++ +Q E N+ +++ +
Sbjct: 14677 ITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKV 14736
Query: 2090 ATLNDELLNEKDDKK-------CIVEADK---------QALESKV-SVFEAAIATLND-- 1968
T EL + K+ KK + +AD Q LE+KV V + T D
Sbjct: 14737 -TYKTELEDSKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLTDYTTQDQE 14795
Query: 1967 ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1788
EL +E ++K I+ + N + Q L+ + E K+ + + LER+++ + + L
Sbjct: 14796 ELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLS 14855
Query: 1787 -----KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH-EEL 1626
++ +K + Q + + + + + E ++ I +E
Sbjct: 14856 LTQEIDHLAQIKTEMQQIEIKMQIQT---------------RSVATQWETDVQIQQGQEA 14900
Query: 1625 QKEKDDKTALIKDLVAAEPGKR-TVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLA 1449
+ T ++ ++A+ K+ TV ++ L S+ + +++ +E ED +A
Sbjct: 14901 TETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMED---------VA 14951
Query: 1448 IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE 1269
MK I + E + + KS + E E + +E+ + E+ + + H++E
Sbjct: 14952 RMKTIMKMEKDQLEQAKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSN 15008
Query: 1268 KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
+DK + E + K + LE TI + + + ++ KQ ++R ++
Sbjct: 15009 TLDK-----KNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQER--EI 15061
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA----ERQV 921
+ ++ +E ++ ++ K E L N E K D + D D K E Q
Sbjct: 15062 QRGTDDTSNEREKYDEKVTYKTE---LEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQT 15118
Query: 920 LESKVSDM-----ETT--YSTLNNELQQKM----DDNEA-----FLNER----------- 822
LE+KV D+ +TT L++E++ KM + NEA L E+
Sbjct: 15119 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVI 15178
Query: 821 -DGLEAVKQGLEK---RVLDLEATI-HDIEMKTGKDDDYNEAEKQT------------LK 693
+ LE + LEK VL L I H ++KT + ++QT ++
Sbjct: 15179 MESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVATQWETDVQIQ 15238
Query: 692 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ E E +T K+++ + VT+L++ L E +E +D + +E +++
Sbjct: 15239 QEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVERMK 15298
Query: 512 KCICGARDGLSTIK 471
+ +D L K
Sbjct: 15299 TMMKMEKDQLEQAK 15312
Score = 72.8 bits (177), Expect = 1e-09
Identities = 142/713 (19%), Positives = 290/713 (40%), Gaps = 73/713 (10%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ + NDRN+L+ + L+ K+ SI D L+ K+A
Sbjct: 6766 EKELLHNDRNLLKKDVEDLQQKL---------------------MSIERDSESLKLDKEA 6804
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE---ATIATL 2082
EN+ + A+ + +L + D+ + I + ++Q +E K A + I TL
Sbjct: 6805 FENE----KEAMKQMKTDLQIQADEIEKIKLE---THHERQRVEEKTAQIQKEREEINTL 6857
Query: 2081 NDELLNEK---DDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
+E+ ++ D+ + +K+A+ES S E A + + N + I RN L
Sbjct: 6858 VEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNAL 6917
Query: 1910 EAAKQALEYKVADLEAAKTTL---NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE 1740
E + + LE K + +ELER D ++A D +S + ++ + E
Sbjct: 6918 EKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQR-QQEAKDHLLSGITDESLLKKSE 6976
Query: 1739 DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKR 1560
+ ++ +S+ + + + + E D K AL KD + +
Sbjct: 6977 AE---IVLQPSQVDKAKPARKTEISDSDKQPVFVQQ--MPEMDLKDALKKDFESEKLDLP 7031
Query: 1559 TVNEIVSHLESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGK 1398
V +++ + + L++ + +E D++ L++ A + K + E +K D
Sbjct: 7032 KVKDVLP--QDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMA 7089
Query: 1397 SALVE------------NGEGCEAEKQG----LEKTVLERRASNLDTMDAIHEEELRKEK 1266
+ L E N + +KQ +EKT ER + +D + ++ K K
Sbjct: 7090 ARLQEERRTNERLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNK 7149
Query: 1265 VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND------ALQRDL-----------D 1137
+ + + E E + K V + SL+ LQ D+ +
Sbjct: 7150 KTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKN 7209
Query: 1136 RVMAEKQALEKRCSD---LEAKNASLTDNQEGHEAEIER-KLEASNLTHN--DELHKEKD 975
+M E L++R SD L+ + L D + A +ER +LE T N ++ K
Sbjct: 7210 TIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKM 7269
Query: 974 DKES-------IMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 816
+KE+ + + D ++ ER++L + + + EL+ + E NE+
Sbjct: 7270 EKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKE 7329
Query: 815 LEAVKQGLEKRVL----------DLEATIHDIEMKTGKDDDYNE--AEKQTLKKRISELE 672
LE +K L+++ + D + ++ + + D +E AE + +++R+ + E
Sbjct: 7330 LEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTE 7389
Query: 671 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ K +K +++ E T+LQ+ + + +++++ ++ EL + E
Sbjct: 7390 K-------KRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKE 7435
Score = 71.2 bits (173), Expect = 4e-09
Identities = 110/577 (19%), Positives = 245/577 (42%), Gaps = 27/577 (4%)
Frame = -2
Query: 2189 EKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALES 2010
EK ++ + +N+ ++L + + + + +L E+++ + I+ + +E
Sbjct: 12938 EKQKEEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRME- 12996
Query: 2009 KVSVFEAAIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1833
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 12997 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 13054
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1659
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 13055 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 13096
Query: 1658 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1479
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 13097 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 13156
Query: 1478 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 1305
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 13157 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 13212
Query: 1304 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 13213 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 13270
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDE--LHKEK 978
+ ++ + +K L+ S+L + L D E++ + E S DE L +E+
Sbjct: 13271 EESMNEMTKKKSELQHERSELYKQKQQLED-MIASESKRDVDTERSRQDKEDEQILKRER 13329
Query: 977 DD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 810
++ K+ ++ + + V+ ++ + + +E S LN++ ++ +N+ L + ++
Sbjct: 13330 EEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQ 13389
Query: 809 AVKQGLEKRVLDLE-------ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILT 651
LEK + DL+ A + + + + D E K+ K +E++ +
Sbjct: 13390 VKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIE 13449
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+L+ + N ++ ++ +L S+E ++L K+
Sbjct: 13450 SVKVRLVTESN----QIDKMNSELKTRSEELENLIKK 13482
Score = 68.6 bits (166), Expect = 3e-08
Identities = 127/670 (18%), Positives = 270/670 (40%), Gaps = 78/670 (11%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
+R LE K AL+++ + E ++ E + + + + +E KQ +EN+ A+
Sbjct: 12739 ERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAE 12798
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
E + + ++ K ++ + + Q E V + T+ DEL +++
Sbjct: 12799 LEIDLENI---IIETKSKQERLESIEVQLQEKNVQM-----GTILDELNKRQEE------ 12844
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
L+A K + + + + DEL I+K+ +++ + + ++D
Sbjct: 12845 ----LDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKD 12900
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE----------LQKEKDDKTAL 1596
Q +M A + +E++ L+L+ E L+K+K++ +
Sbjct: 12901 QFGNMQAELQKGQL-------------EMEMHQLMLNSERDELNGMRVNLEKQKEEFELM 12947
Query: 1595 IKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVLERSASN 1455
++L + P K+ V E+ + L + + E R E+ + +E
Sbjct: 12948 QQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKT 13007
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT-MDAIHE--E 1284
I A EE +KE D + + E CE ++ + + L + + +D D I + +
Sbjct: 13008 KQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEIDIERDEIQKLRK 13063
Query: 1283 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA----------LQRDL-- 1140
+ KEK + + + + E EK E ++ I SL + LQ L
Sbjct: 13064 QYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKLRE 13123
Query: 1139 -----DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEA------------- 1017
D + EK LEK+ +++E DN + E K+EA
Sbjct: 13124 AENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNYLE 13183
Query: 1016 ---SNLTHND---------------ELHKE-KDDKESIMNDLDHVKAERQVLESKVSDME 894
NLT EL+K+ K+ +E M+ ++ +AER+ +E + +M
Sbjct: 13184 QMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERVMDEMA 13243
Query: 893 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY-- 720
+ + E ++ ++ E +R LE + K+ +L+ ++ + + +D
Sbjct: 13244 EEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLEDMIA 13303
Query: 719 NEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+E+++ +R + +E IL + +++ + L E +++ + ++EK+ +EK
Sbjct: 13304 SESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKM 13363
Query: 539 VLELTSKLEK 510
+L + E+
Sbjct: 13364 QSQLNDQKEE 13373
Score = 66.2 bits (160), Expect = 1e-07
Identities = 120/590 (20%), Positives = 242/590 (41%), Gaps = 46/590 (7%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
+R + A+ Q + ++ T+ + DE+ + ++ + + L K ++ E
Sbjct: 8011 ERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKNM-EKTYE 8069
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL----------NDELER 1830
NDE+ EK I + + +L + LE ADLE K + N+ LER
Sbjct: 8070 QQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLER 8126
Query: 1829 KKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1671
+K D II+ +A +R ++ A A +RD E+ M + +
Sbjct: 8127 EKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQEASKNQMV 8185
Query: 1670 --------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH---LESK 1524
+ L+ ++L EL+K K D + DL ++T +EI+ H +SK
Sbjct: 8186 ELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKHEKDTDSK 8239
Query: 1523 SRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENGEGCEAEK 1356
+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 8240 TRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM----------- 8287
Query: 1355 QGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEKQGPEKTV 1194
K V+ +R D M+ I EE+ +E+ + L N + + + +
Sbjct: 8288 ----KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERT 8339
Query: 1193 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEAS 1014
+LE ++ D++R++ E + + +L+ E+ER++E S
Sbjct: 8340 ANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EMERRMEKS 8380
Query: 1013 NLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTLNNELQQK 855
+ DE K + + + D+ ++ L ++ ++E + L + Q++
Sbjct: 8381 KV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQ 8439
Query: 854 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 675
E ER+ LE +K + + D+E +E K++ + Q K+ + +
Sbjct: 8440 ESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSV 8499
Query: 674 EEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 528
E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8500 TE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8545
Score = 65.9 bits (159), Expect = 2e-07
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -2
Query: 1565 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1389
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1388 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1209
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1208 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1029
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1028 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 900
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 899 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 723
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 564
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 563 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 399
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 398 RKTSPLDITKT-----CDAVDISEDST 333
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.9 bits (159), Expect = 2e-07
Identities = 125/657 (19%), Positives = 260/657 (39%), Gaps = 68/657 (10%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
I ++ +E++K L + D E A L + DK+ ++ + ++E +K +
Sbjct: 8075 IQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKI 8134
Query: 2114 VADFEATIATLNDELLNE------KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNE 1953
+ + E+ E E +D ++ + + + ++E + + L ++
Sbjct: 8135 IENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQEASKNQMVELKRQIDKL 8194
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---------------ELERKKDD 1818
+ K ++ + L+ K L+ ++ DLE ++ + E++R+KDD
Sbjct: 8195 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 8254
Query: 1817 NNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-- 1656
I+K L+KR + L+++ ++D + M +I +
Sbjct: 8255 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 8314
Query: 1655 -VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSRSLK--- 1509
+ IL +Q + D +TA ++D +A +R V E+V + R+LK
Sbjct: 8315 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVRNLKGEM 8373
Query: 1508 EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLEKTVL 1332
E + + + E+ E+ I + I++ ++R+ G +E + E + + +
Sbjct: 8374 ERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 8433
Query: 1331 ERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT-VLDLE 1182
E++ + +H+E E+ +EK D E E +++ E T + +
Sbjct: 8434 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 8493
Query: 1181 PTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1011
+ S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +K E
Sbjct: 8494 EELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-KKGEQLL 8552
Query: 1010 LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 831
DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8553 EKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDLFRSELQ 8612
Query: 830 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------------ 687
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8613 RQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKIRFDIAN 8669
Query: 686 ----ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 528
I + + IL D + +D + E +L E D+E+ VLE+
Sbjct: 8670 ARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLVLEV 8722
Score = 64.3 bits (155), Expect = 5e-07
Identities = 123/636 (19%), Positives = 256/636 (40%), Gaps = 49/636 (7%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E AK +++ + E + DE+ E + K I + ++ DK ALE + D
Sbjct: 453 IEQAKVDIQSHMISMEGRV----DEIKRETERLKHIKTE---MQRDKDALEKQKDDTRKA 505
Query: 2093 IATLND---ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLND----ELLNEKDDKKC 1935
E++ E+ + + ++ ++ LE+ A + +ND ++L EK++
Sbjct: 506 KEEAERKRYEIVTEELEHRARLQRERDELEN----IRAEMQRVNDVEKAKILKEKEES-- 559
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAP 1755
+ R ++ E A+++A K LN E + I +RI A
Sbjct: 560 -IRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEI------ERIKHETLRAK 612
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
+ + E+ + I + ++E + EE+QK K+ +L
Sbjct: 613 E-EIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKV----EEIQKTKEQMEEAKVELEEE 667
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEED-------------EVLERSASNLAIMKAI 1434
++VS ++ L+ LR +E+ E+ ++ L ++ +
Sbjct: 668 REDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLEKL 727
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
REE R +K+ + + +E L K L++ ++ + ++ + K +
Sbjct: 728 REETERSQKNIEESKIE---------LMLWKESLDKLKGEMEEDKHVVIMQMNEAKAKEE 778
Query: 1253 ALTENGEGCEAEKQ----GPEKTVLDLEPTIPSLNDALQR------DLDRVMAEKQALEK 1104
LT E E E+ EK +L+ I + + LQR D RV+ K+ E
Sbjct: 779 QLTMVIEQLEIERGEITISREKVKEELDE-INRMRNELQRQHAEMEDWFRVV-NKEKEEA 836
Query: 1103 RCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDELHKEKDDKESIMNDLDHVKAE- 930
+ L A + ++ E+E R ++ L DE+ K+ ++ E I ++ + E
Sbjct: 837 NLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAEELEQINKEIQRARQEL 896
Query: 929 -----------RQVLESKVSDMETTYSTLNNELQQKMDDNEAFL---NERDGLEAVKQGL 792
+++LE + + L+ K D ++ +ER LE ++ +
Sbjct: 897 EKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSERKELEQMRFQV 956
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL---EEAISILTDKAKKLLKDI 621
E DLE +++ + + +K+ L+K S+L E+++ + A++ +
Sbjct: 957 ENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKA 1016
Query: 620 NIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ + E+ E +ED+NK +E + E+ + L +E
Sbjct: 1017 ELLIVEIQEQREDVNKRLEETKQREEALRLLRKDME 1052
Score = 63.5 bits (153), Expect = 8e-07
Identities = 123/686 (17%), Positives = 275/686 (40%), Gaps = 44/686 (6%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++DK V+ N +A ++ L + E I RN L+
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 2258 QALEN--KVGDFEAAIATLNDELLNEKD---DKKCIVNDRNIVEADKQALENK--VADFE 2100
+E+ +V + E A L ++E + K+ +++ E +ALE + +
Sbjct: 820 AEMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKA 879
Query: 2099 ATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA---IATLNDELL-NEKDDKKCI 1932
+ +N E+ + + + + +K++L+ + + + + ELL N+ D KC+
Sbjct: 880 EELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCL 939
Query: 1931 V---NDRNILEAAKQALEYKVADLEAAKTTL-------NDELERKKDDNNAIIKKALDKR 1782
++R LE + +E + DLE + + + +++R+K++ I + +
Sbjct: 940 FEMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDT 999
Query: 1781 ISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
S ++ R + LI + E + +L ++++ E++D
Sbjct: 1000 ESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENERED-- 1057
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE 1422
L K V GK T E+ + ++ + E+ + ER N + IR+ E
Sbjct: 1058 -LEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKME 1116
Query: 1421 LRKEKDGK--SALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR-KEKVDKSA 1251
K + G+ VE + E +E LE +NL+ M A + LR KE ++
Sbjct: 1117 AMKREMGEIEDMKVELTKQKENIDMKMEHARLEM--TNLEMMKA---DLLRQKEDIENQM 1171
Query: 1250 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
L E + E E +L + + + + +++++ K ++K+ +LE +
Sbjct: 1172 LAAKSERQQMEVMRTE--ILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 1070 LTDNQEGHEAEIERKLEASNLTHNDELH---KEKDDKESIMNDLDHVKAERQVLESKVSD 900
T + G ++R++E + + ++K++ E + ++ K + + +
Sbjct: 1230 -TKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQRAKDDMEFKRVETER 1288
Query: 899 METTYSTLNNELQQKMDDNEAFLNERD-----------------GLEAVKQGLEKRVLDL 771
+ + E+Q+ ++ E + ERD +EA ++ + K
Sbjct: 1289 QKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIINLIQQIEATREMVHKTKFQF 1348
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
E + +M T ++ N AE Q L I + E + L + ++ + + E+ L
Sbjct: 1349 ENRMAGSQMGTADQEEMN-AEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLL 1407
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLE 513
+ ++ + +E + E++++ +LE
Sbjct: 1408 KIEVQRRRREIEYREEKIMREQDELE 1433
Score = 61.2 bits (147), Expect = 4e-06
Identities = 115/678 (16%), Positives = 265/678 (39%), Gaps = 38/678 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++ + + + +E K ++ ++ D E + + +R LE +
Sbjct: 616 ENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKR 675
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLN 2079
+ ++ E L +E+L K+ E + + E + + E T +
Sbjct: 676 DLVSREIEQAEF----LRNEILRVKE------------EMESRWRETETEEVELRAKTQH 719
Query: 2078 D----ELLNEKDDKKCIVEADKQALESKVSV--FEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ E L E+ ++ + K ESK+ + ++ ++ L E+ ++DK ++ N
Sbjct: 720 ELERLEKLREETER-----SQKNIEESKIELMLWKESLDKLKGEM---EEDKHVVIMQMN 771
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQED 1737
+A ++ L + LE + + E+ K++ + I ++ ++L+ Q
Sbjct: 772 EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEI-----NRMRNELQR------QHA 820
Query: 1736 DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK-TALIKDLVAAEPGKR 1560
+M V E+ + EE +K + + T ++ +
Sbjct: 821 EMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAE 880
Query: 1559 TVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALV 1386
+ +I ++ + L++ +F +E ++LE + ++ +R E L+ + D L
Sbjct: 881 ELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLF 940
Query: 1385 E-NGEGCEAEKQGL----EKTVLERRASNLDTMDAIHEEELRKEK-----------VDKS 1254
E + E E E+ EK LE+R + D +++++K +D
Sbjct: 941 EMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTE 1000
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMA----------EKQALEK 1104
++ + E +++ E +++++ +N L+ R A E++ LEK
Sbjct: 1001 SMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDLEK 1060
Query: 1103 -RCSDLEAKNASLTDNQEGHE--AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA 933
R L K+ +E + AEIER + + +E K +KE ++ ++ +K
Sbjct: 1061 IRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKR 1120
Query: 932 ERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHD 753
E ++ DM+ + + KM+ E LE +K L ++ D+E +
Sbjct: 1121 EM----GEIEDMKVELTKQKENIDMKMEHARL---EMTNLEMMKADLLRQKEDIENQM-- 1171
Query: 752 IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+ + E + + K+ ++E + + + +K+ + + EL+E + K
Sbjct: 1172 --LAAKSERQQMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 572 ESKEKQDLEKRVLELTSK 519
+E ++E E+ K
Sbjct: 1230 TKREIGEMELMKREMEGK 1247
>ref|XP_009292627.1| PREDICTED: nesprin-1 isoform X3 [Danio rerio]
Length = 15657
Score = 116 bits (291), Expect = 8e-23
Identities = 145/673 (21%), Positives = 300/673 (44%), Gaps = 29/673 (4%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I +L+ + + K D++ N+R +++ K LE + + E
Sbjct: 6397 IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKI 6456
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + + K I +D++
Sbjct: 6457 KLETQHDR--QRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKD 6514
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-R 1749
+LE K LE ++L K ++LE++K++ A I+K L+K ++ + + +
Sbjct: 6515 MLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQIQKEREDLEKMNENITREMHEIK 6570
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLV 1581
QE+ MN + L+ I L +EL+KEK+ ++ L +
Sbjct: 6571 HQEEQMNQ--------------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQS 6616
Query: 1580 AAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
+ + +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+L+ K
Sbjct: 6617 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKL 6676
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTEN 1239
K + E E K LE+ + R +T + EEL+KE+ D + L E+
Sbjct: 6677 QKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED 6736
Query: 1238 GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+ EK ++ + E ++ L Q++ + K+ + K+ D+E + D
Sbjct: 6737 ---TKREKNSLDEMKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DK 6785
Query: 1058 QEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYST 879
E E+E+ L+A E+HK++ + E + +++ ER + V D+++ +
Sbjct: 6786 IRLREDELEQ-LQA-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIIS 6834
Query: 878 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDD 723
L+ + + D EAF NE++ L+ +K LE+ ++E T H+ EM +
Sbjct: 6835 LDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMET 6894
Query: 722 YNEAEKQTLKKRI------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 561
N KQ K ++ E+E+ + K L +D+ + ++ L+E+ NK +
Sbjct: 6895 MNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQM 6954
Query: 560 KQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPL 381
K LE+ E+ SK+++ R L + A + E L + RK L
Sbjct: 6955 KIGLEREADEI-SKIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVL 7004
Query: 380 DITKTCDAVDISE 342
D K + +++
Sbjct: 7005 DKIKVANESTLAD 7017
Score = 112 bits (280), Expect = 2e-21
Identities = 144/655 (21%), Positives = 283/655 (43%), Gaps = 63/655 (9%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ E KQ +E + D
Sbjct: 4636 EKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHD 4695
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
F+ + +L+++L K K+ I E + + K+ + A DE+ K++ + N
Sbjct: 4696 FDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREA-----DEIRKVKEETQ---N 4747
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
+R I E +AL+ + DL N L+ K N + + L +R S+L ++
Sbjct: 4748 ERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRER-SNL------QE 4800
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLVA 1578
++++ + + L+ I E +KEK ++ A+IKD+
Sbjct: 4801 MRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVED 4860
Query: 1577 AEPGKRTVNEIVSHLESKSRSLK---EHFLREEED-----EVLERSASNLAIMKAIREEE 1422
+ ++I+S L+ + SLK E F E+E+ LER A + +K + E
Sbjct: 4861 LQ------SKIIS-LDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHE 4913
Query: 1421 LRKEKDGKSALVE--NGEGCEAEKQGLE----KTVLERRASNLDTMDAIHEEELRKEKVD 1260
++ ++ + +E N E + K E K +E+ ++D ++ L+ K+
Sbjct: 4914 RQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQ 4973
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK 1080
K + E EK E+ ++LE D +++ + E+Q LEK +L+ +
Sbjct: 4974 KQVI-------EEEKNKLEQMKIELEKEA----DEIRKIKEETQNERQRLEKMTEELKKE 5022
Query: 1079 NASLTDNQEGHEAE--IERKLEASNLTHNDELHKEKDDKESIM----------------- 957
S T E + E I K++ +N + +L KEK + E +
Sbjct: 5023 KESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKI 5082
Query: 956 ----NDLDHVKA------------------ERQVLESKVSDMETTYSTLNNELQQKMDDN 843
++L+ ++A ER + V D++ +L+ +L+ D
Sbjct: 5083 RLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDR 5142
Query: 842 EAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAI 663
EAF NER+ L+ +K L+++ ++E I+++T D E ++K ++ I
Sbjct: 5143 EAFENEREVLKQIKTDLKRKAEEIE----KIKLETQHDRQRVEEMTAQIQKERDKINNLI 5198
Query: 662 SILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEK---RVLELTSKLEK 510
T++ +L +I + E + ++ D + KEK DLEK ++L LEK
Sbjct: 5199 E-ETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEK 5252
Score = 112 bits (280), Expect = 2e-21
Identities = 150/630 (23%), Positives = 279/630 (44%), Gaps = 43/630 (6%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT- 2094
E+ + A+ V D + + +L+ +L + K D++ N+R +++ K L+ K + E
Sbjct: 5111 ESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIK 5170
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ T +D E+ + E DK + + + LN+ K+ K I +DR++
Sbjct: 5171 LETQHDRQRVEEMTAQIQKERDK--INNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDM 5228
Query: 1913 LEAAKQALEYKVADLEAAKTTLND-------ELERKKDDNNAIIKKALDKRISDLKADAP 1755
LE K LE + L AK L E++++++D + +K I D+K
Sbjct: 5229 LEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEK-FTIEIHDIKHQEE 5287
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKD 1587
Q Q+ D + L+ I L +EL+KEK+ D++ L D
Sbjct: 5288 QMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL--D 5325
Query: 1586 LVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELR 1416
L +E K+ VN+I+ ++++ + L K+ EE+ + +E+ + + +E+L+
Sbjct: 5326 LRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLK 5385
Query: 1415 KEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 1236
K K L + E K LE+ +E R + I E EK+ + AL E
Sbjct: 5386 MMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK----EEIQNERQNLEKMTE-ALKEER 5440
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1056
E E + + + +++ S + R+ + ++ + K+ D+E K +N
Sbjct: 5441 EDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK----ENL 5496
Query: 1055 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E E+ R+L+A E+ KEK + ES ER + V D++ L
Sbjct: 5497 RLREDEL-RQLQAEIHKQQREIEKEKINIES----------ERAAIIKDVEDLQHKIICL 5545
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD--------IEMKTGK 732
+ + + D EAF NE++ L+ +K LE+ ++E T HD +++ +
Sbjct: 5546 DRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDR 5605
Query: 731 DDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLN 576
D+ N E+ L ++ ++EE I SI +DK +K D+ SE+ +++EDL
Sbjct: 5606 DEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLE 5665
Query: 575 KE--------SKEKQDLEKRVLELTSKLEK 510
K+ KE++DLEK +T ++ +
Sbjct: 5666 KQKENTLAEIQKEREDLEKMNENITREMHE 5695
Score = 110 bits (276), Expect = 5e-21
Identities = 145/650 (22%), Positives = 280/650 (43%), Gaps = 52/650 (8%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
++ KQ +E + D + + +L+ L K K+ I ++N +E K LE + +
Sbjct: 4942 MQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKI 5001
Query: 2093 ----------IATLNDELLNEKDDKKCIVE---ADKQALESKVSVFEAAIATLNDELLNE 1953
+ + +EL EK+ + E +K+ L+ E+ +A L E N
Sbjct: 5002 KEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNL 5061
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNN----AIIKK- 1797
++ ++ I E K+ + + +LE + ++ E++ +K +N AIIK
Sbjct: 5062 EEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDV 5121
Query: 1796 --------ALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VNIL 1644
+LD+ + LK D + E ++ I K+ + + +
Sbjct: 5122 KDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVE 5181
Query: 1643 ILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK-EHFLREEEDEVLER 1467
+ ++QKE+D LI++ + +NEI + ++ K ++++ + + E+E LE+
Sbjct: 5182 EMTAQIQKERDKINNLIEETNRKD---MVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEK 5238
Query: 1466 SASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 1287
+ S L K E L K++ K A ++ E++ LEK ++ D H+
Sbjct: 5239 TRSKLLRAK----ENLEKQRKIKLAEIQK------EREDLEKM---NEKFTIEIHDIKHQ 5285
Query: 1286 EELRKEKVDKSALTENGEGCEAEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQAL 1110
EE K+K D+ LD L+ I +L L+++ + +M ++ L
Sbjct: 5286 EEQMKQKQDE---------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL 5324
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----KESIMNDL 948
+ R S+L+ + ++ D E + E ++ K + E+ KEK D ++S+ DL
Sbjct: 5325 DLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDL 5384
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
+K ++QVLE + S +E L E + E NER LE + + L++ DL
Sbjct: 5385 KMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL- 5443
Query: 767 ATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISILTDKAKKLLKDINIWLS 606
+ + D+ A + TL K + E+ E IS T+ + +++ +
Sbjct: 5444 --AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLRED 5501
Query: 605 EVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCICGARDGLS 480
E+ +LQ +++K+ KEK ++E + +E K IC RD S
Sbjct: 5502 ELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAES 5551
Score = 110 bits (275), Expect = 6e-21
Identities = 160/704 (22%), Positives = 306/704 (43%), Gaps = 60/704 (8%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAA 2262
EKDD ++ D + + L E+A+A +S+ ++++
Sbjct: 3517 EKDDLAHLAEDTKRKDDEMKVLH------ESALADIQKEKCNLEQMRESMFKQNEMIDSE 3570
Query: 2261 KQAL---ENKVGDFEAAIATLNDELLNEKDDKKCIV-NDRNIVEADKQALENKVADFEAT 2094
K+ + E+K+ +A I E+ D KK I+ N+R + Q L ++
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEM----DTKKSIIENERAAMTKKNQDLMTELTKQSED 3626
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ E+L EK+ ++E+D++ L+ V + + + + + K D++ + N++ +
Sbjct: 3627 VEIQMKEVLTEKE----LLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEV 3682
Query: 1913 LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---------LDKRISDLKAD 1761
L+ K L+ + ++E K E +R ++ I K + + I D+K
Sbjct: 3683 LKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQ 3742
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 3743 EKQMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL- 3781
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ +E+ + + +E+
Sbjct: 3782 -DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1248
L+ K K E EK LE K LER A + + +EE++ E+ +
Sbjct: 3841 LKMMKLQKQVF-------EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKM 3889
Query: 1247 TENGEGCE------AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
TE + + AE E+ +LD ++ SL LQ++ ++ + K+ D+
Sbjct: 3890 TEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDV 3949
Query: 1088 EAK--NASLTDNQEGH-EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL 918
+ K N L +++ G +AEI ++ E+ KEK + ES ER +
Sbjct: 3950 KNKKENLRLREDELGQLQAEIHKQQR--------EIEKEKSNIES----------ERAAI 3991
Query: 917 ESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDI 750
V D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T HD
Sbjct: 3992 IKIVEDLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDR 4051
Query: 749 E-------MKTGKDDDYNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDIN 618
+ T + D N ++T L ++ ++EE I SI +DK +K ++
Sbjct: 4052 QRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLE 4111
Query: 617 IWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 4112 KTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHE 4155
Score = 110 bits (275), Expect = 6e-21
Identities = 135/650 (20%), Positives = 282/650 (43%), Gaps = 65/650 (10%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ + + + + + +ND + K+++K + D+ +E KQ +E + D
Sbjct: 6183 EKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHD 6242
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
F+ + +L+ +L K K+ E + + K+ + A + +
Sbjct: 6243 FDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKM 6302
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1806
+EL EK+ + D + IL+ K A E +ADL+ K+ L + E +
Sbjct: 6303 TEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDV 6362
Query: 1805 IKKALDKRISD-----LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1641
K + R+ + L+A+ ++ +E + + I+ N+E +
Sbjct: 6363 ENKKENLRLREDELWQLQAEIYKQQREIEKEKI--------NIESERAAIIKNVED---L 6411
Query: 1640 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE------ 1479
H+ + ++D + +L D A E + + ++ + LE ++ +++ L + D
Sbjct: 6412 QHKIISLDRDSE-SLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEM 6470
Query: 1478 ----VLERSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---- 1338
+R N I + R++ + EK+ ++ + + E EK LEKT
Sbjct: 6471 TAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSEL 6530
Query: 1337 -----VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEP 1179
LE++ N T+ I +E EK++++ E E E+Q +K + L+
Sbjct: 6531 YKVKEDLEKQKEN--TLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 6588
Query: 1178 TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLT 1005
I +L L+++ + +M + L++R S+L+ + ++ D E + E ++ K +
Sbjct: 6589 EIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 6648
Query: 1004 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 837
E+ KE+D+ ++S+ DL +K ++QV+E + + +E L E E
Sbjct: 6649 QKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEE 6708
Query: 836 FLNERDGLEAVKQGLEKRVLDLEATIHDI--------EMKTGKDDDYNEAEKQTLKKRIS 681
N+R LE + + L+K D+ D EMK + + +K+ K +
Sbjct: 6709 TQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKE--KSNLE 6766
Query: 680 ELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 531
E++E IS T+ +K I + E+ +LQ +++K+ E ++EK +E
Sbjct: 6767 EMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSE-TEIEKSNIE 6815
Score = 108 bits (270), Expect = 2e-20
Identities = 151/639 (23%), Positives = 281/639 (43%), Gaps = 55/639 (8%)
Frame = -2
Query: 2261 KQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL 2082
K+ L N + L +L++ + D K + DR E +K+A++ D + +
Sbjct: 5977 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 6036
Query: 2081 NDELLNEKDDKKCIVEADKQALESKVSVFEAAIAT-LNDELLNEKDDK-----KCIVNDR 1920
L + D++ + E Q + + + T D +LNEK+ K I +D+
Sbjct: 6037 EKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDK 6096
Query: 1919 NILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
++LE + LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 6097 DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM-NENITREMHEIKHQ 6155
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q +Q+ D + L+ I L +EL+KEK+ D++
Sbjct: 6156 EEQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQF- 6194
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ + + +++
Sbjct: 6195 -DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKD 6253
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-----EELRKEKVDK 1257
L+ K K E E K LE+ E R +T + EEL+KEK
Sbjct: 6254 LKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESF 6313
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1077
+ L E+ + E+ +LD + N++L DL + EK LE+ ++ +
Sbjct: 6314 THLAEDTK--------KEQEILD---KVKVANESLMADLQK---EKSNLEEMRENISKQT 6359
Query: 1076 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
+ + +E + +L+A E+ KEK + ES ER + V
Sbjct: 6360 EDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIES----------ERAAIIKNVE 6409
Query: 902 DMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEM 744
D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T HD +E
Sbjct: 6410 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 6469
Query: 743 KTG---KD-DDYNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSE 603
T KD D N ++T L ++ ++E+ I SI +DK +K D+ SE
Sbjct: 6470 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSE 6529
Query: 602 VTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 6530 LYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHE 6568
Score = 105 bits (263), Expect = 1e-19
Identities = 126/642 (19%), Positives = 281/642 (43%), Gaps = 46/642 (7%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLND-------ELLNEKDDKKCI-------VN 2160
+I +DR++LE K LE A L E+ E++D + + ++
Sbjct: 5221 AIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIH 5280
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
D E + ++++ + I L EL EK+ I+ D+ L+ + S +
Sbjct: 5281 DIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKE----IIMKDRSQLDLRQSELDKQQT 5336
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII- 1803
+ND + K+++K + D+ E KQ +E + D + ++ +L+++L+ K +
Sbjct: 5337 NVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLED 5396
Query: 1802 -KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
K L++ +L+ +A + + +E+ N + + N +L E
Sbjct: 5397 EKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDE 5456
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFLREEEDEV------ 1476
+ ++++ E + +++ +E+K +L+ E LR+ + E+
Sbjct: 5457 MKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQRE 5516
Query: 1475 LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAEKQGLE--KTVLER 1326
+E+ N+ AI+K + + + + ++D +S ++ E E EK+ L+ KT LER
Sbjct: 5517 IEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENEKEVLKQMKTELER 5575
Query: 1325 RASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQR 1146
A ++ + E + +++V++ A + E E D+ + N ++
Sbjct: 5576 EADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM--VLNEKNRDIEE 5631
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ + ++K LEK DLE + L +E E + E L E+ KE++D
Sbjct: 5632 KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA--------EIQKEREDLE 5683
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
E+I ++ +K + + + K +++ + + N Q+ + E + +R L+ +
Sbjct: 5684 KMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQS 5743
Query: 797 GLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 627
L+K+ + D+ T+ + + KD + E +KQ ++K ++++ L + KK+
Sbjct: 5744 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKL 5803
Query: 626 DINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 510
++ E +L++ +L +E+ E +++ +LEK
Sbjct: 5804 QKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 5845
Score = 104 bits (259), Expect = 4e-19
Identities = 127/622 (20%), Positives = 279/622 (44%), Gaps = 40/622 (6%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I L+ + + K D++ N++ +++ K LE + + E
Sbjct: 5524 IESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKI 5583
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + ++ K I +D++
Sbjct: 5584 KLETQHDR--QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5641
Query: 1916 ILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+LE K LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 5642 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKM-NENITREMHEIKHQE 5700
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIK 1590
Q +Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 5701 EQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL-- 5738
Query: 1589 DLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+
Sbjct: 5739 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQ 5798
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKT------VLERRASNLDTMDAIHEEELRKE---- 1269
+K K K E E K LE+ + E + ++ + EE +R++
Sbjct: 5799 KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLA 5858
Query: 1268 ------KVDKSALTEN---GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1116
K +K L E E A+ Q + + ++ I L + + + ++ +
Sbjct: 5859 HLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLRED 5918
Query: 1115 ALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNLTHNDELHKEKDDKE----SIMND 951
L+K ++++ + + + + E+E + E N+ EL K+ +D E I+ +
Sbjct: 5919 ELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMM--TELKKKSEDVEIQMKEILTE 5976
Query: 950 LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 771
+ + +R++L V +++ L + ++ D EAF NE++ ++ +K L+ + ++
Sbjct: 5977 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 6036
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE-VTE 594
E I+++T D E ++K ++ I T++ +L + N + E +
Sbjct: 6037 E----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE-ETNRKDMVLNEKNRDIEEKIKS 6091
Query: 593 LQEDLNKESKEKQDLEKRVLEL 528
+Q D + KE+ +LEK EL
Sbjct: 6092 IQSDKDMLEKERHNLEKTRSEL 6113
Score = 100 bits (250), Expect = 5e-18
Identities = 127/675 (18%), Positives = 292/675 (43%), Gaps = 46/675 (6%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ + +++++L K L+N+ + + ++ +++ +
Sbjct: 12220 ERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEE 12279
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N++ + + + + +R + + L+ ++ +F+A ++ +E
Sbjct: 12280 TRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEE 12339
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L ++ + K E K E+K ++ E +E+ EK+ ++ R +E ++
Sbjct: 12340 DLPKEKEMK---EDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKE 12396
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNAL 1722
+E + LE ++ ++ E ++ DD I K+ L+K S++ Q ++E +++
Sbjct: 12397 IEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKK 12456
Query: 1721 IXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK-----------DDKTALIKDLVAA 1575
I +IV L V + E+Q +K D++ LI++ +
Sbjct: 12457 IKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQ 12516
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEEL 1419
+ + E+ ++ + +LKE + +EE + V+E R +L M E+
Sbjct: 12517 QNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQK 12576
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI-----------HEEELRK 1272
+ + + L + E E+ + T L++R +T I +E+L++
Sbjct: 12577 QDLMNQRDLLKQ-----EREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQ 12631
Query: 1271 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1092
+ ++ E E + E + ++ D L+++ E++ L+K+ D
Sbjct: 12632 AIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADD 12691
Query: 1091 LEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAE 930
LE + D +E + + E+KL + +N L D+L KEK+D N+LD ++ E
Sbjct: 12692 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 12751
Query: 929 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEAT 762
Q ++++ +++ T E+ ++ E LN ER LE V+ EK +
Sbjct: 12752 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQ 12807
Query: 761 IHDIEMKTGKD-DDYNEAEKQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
I ++ +KT + D+ ++ + L +K ++ I +L + ++ +++ ++ EL
Sbjct: 12808 IEEMRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEEL 12864
Query: 590 QEDLNKESKEKQDLE 546
+ + K EK+DLE
Sbjct: 12865 KLEKQKIQNEKKDLE 12879
Score = 100 bits (248), Expect = 8e-18
Identities = 135/693 (19%), Positives = 298/693 (43%), Gaps = 107/693 (15%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ +E KQ +E + +
Sbjct: 6600 EKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDN 6659
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
+ + +L+++L K K+ I E + + K+ + A + +
Sbjct: 6660 MDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKM 6719
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------EL 1836
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++
Sbjct: 6720 AEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDI 6779
Query: 1835 ERKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXX 1698
E++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6780 EKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDA 6839
Query: 1697 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LE 1530
+ N + + + EL++E D+ + K + + ++ V E+ + +
Sbjct: 6840 ESLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMN 6896
Query: 1529 SKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQ 1353
++ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K
Sbjct: 6897 NERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKI 6956
Query: 1352 GLE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEA 1221
GLE K + NL+ M +A+ EE E++++ + E A
Sbjct: 6957 GLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLA 7016
Query: 1220 EKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA 1041
+ Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+
Sbjct: 7017 DLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIES 7076
Query: 1040 EIERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E + E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 7077 ERAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSI 7134
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK----- 732
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 7135 ERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKER 7194
Query: 731 -----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 609
D+ Y E EK+ ++ S+LE+A S + K K+I I L
Sbjct: 7195 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIAL 7250
Query: 608 SEVTELQEDLNKESKE------KQDLEKRVLEL 528
+E+ + + L K SKE K + EK+ ++L
Sbjct: 7251 AEIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 7283
Score = 99.4 bits (246), Expect = 1e-17
Identities = 143/698 (20%), Positives = 299/698 (42%), Gaps = 53/698 (7%)
Frame = -2
Query: 2249 ENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL-NDE 2073
++++ + I L EL EK+ I+ DR+ ++ + L+ + + I T+ N+
Sbjct: 4167 QDELDQLKTEIQNLQQELEKEKE---IIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 4223
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L +KD ++ +E KQ +E + + +I +L+++L K K+ I ++N LE K
Sbjct: 4224 KLLDKDKEE--MEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFE 4281
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMNALI 1719
L+ + ++ K +E + + A+IK+ D + L A+ +R++E D+M
Sbjct: 4282 LQREADEIRKIKEETQNERQSLEKMTKALIKERED--LVHL-AEYTKREKEMLDEMQVA- 4337
Query: 1718 XXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 1539
+I+ + NI E+++ EK+ +L + + +
Sbjct: 4338 --NKSSMADLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEID 4395
Query: 1538 HLESKSRSLKEHFLREEEDEV--LERSASNLAI-MKAIREEELRKEKDGK---------- 1398
++ S + +RE+++ + L++ + ++ I MK I E+ E D
Sbjct: 4396 MEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLK 4455
Query: 1397 ---SALVENGEGCEAEKQ--GLEKTVLERRASNLDTMDAIHEEELRKEKV----DKSALT 1245
++ + E + +++ G EK VL++ ++L I +E+ K K+ D+ +
Sbjct: 4456 QKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQ----IQADEIEKIKLETQHDRQRVE 4511
Query: 1244 ENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR----VMAEKQALEKRCSDLEAKN 1077
E + ++ +++ LN+ + RD++ + ++K LEK +LE
Sbjct: 4512 EKTAQIQKDRDEINNLIVETNRKDMVLNE-MDRDIEEKIKSIQSDKDMLEKERHNLEKTR 4570
Query: 1076 ASLTDNQEGHEA--EIERK----------LEASNLTHNDELHKEKDD-----KESIMNDL 948
+ L +E E EIERK E + H +E K+K D K I N
Sbjct: 4571 SELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQ 4630
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
++ E++++ S ++ S L+ + D E NER L+ K+ E++ ++E
Sbjct: 4631 QELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEME 4690
Query: 767 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS-EVTEL 591
HD + D+ + + L+K++ E E K LK + I L E E+
Sbjct: 4691 KEKHDFDQSRKSLDE--DLKMMKLQKQVIEEE----------KSKLKQMKIELEREADEI 4738
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLEKCICGAR------DGLSTIKEAWMSDCMVPDNWV 429
++ + E+Q EK L + E A+ D + E+ ++D + +
Sbjct: 4739 RKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERS-- 4796
Query: 428 PFEDLVQGFSRKTSPLDITKTCDAVDISEDSTTNIQVD 315
+++ + S++T D+ + + + E+ +Q +
Sbjct: 4797 NLQEMRENISKQTE--DVENKKEKIRLREEKLKQLQAE 4832
Score = 99.4 bits (246), Expect = 1e-17
Identities = 138/664 (20%), Positives = 294/664 (44%), Gaps = 74/664 (11%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R+++E ++ + + + N +L+N++D K +R + L+ ++ +F
Sbjct: 11718 RSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLK---QEREEINHKWTQLQQRIDEF 11774
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+A ++ +E L ++ K + E K E+K+ + E T +++ EK+ ++ V
Sbjct: 11775 DAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVM- 11830
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
R +E K+ L+ + LE ++ ++ E ++ DD I K+ L+K S++ Q
Sbjct: 11831 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11890
Query: 1748 DQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEV-------NILILHEEL----QKEKDDK 1605
++E +++ I +IV L V +I + EEL QK D++
Sbjct: 11891 EEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQ 11950
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE---HFLREEED-------------EVL 1473
++++ + + E+ ++ + +LKE H +E+E+ E L
Sbjct: 11951 GLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDL 12010
Query: 1472 ERSASNLA-----------IMKAIREE------ELRKEKDGKSALVENGEGCEAEKQGLE 1344
E+ ++++ ++K REE +L++ D A V + + KQ
Sbjct: 12011 EKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQ--- 12067
Query: 1343 KTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 1170
K + E R S +T I E + + E K+ K E E A+ + ++ + ++ +
Sbjct: 12068 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLE 12127
Query: 1169 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHN 999
+ + + ++ +K+ +E+ DLE + + ++ E +E+E K+ + +
Sbjct: 12128 RVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKC 12187
Query: 998 D-ELHKE---------KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 849
D E KE ++ K I + + ERQ + + + S L NE ++ +
Sbjct: 12188 DIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKN 12247
Query: 848 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD-----DYNEAEKQTLKKRI 684
NE ER+ L+ ++ LEK ++++ E + K+D + +KQ L+ +
Sbjct: 12248 INEVIKKERETLKEMEAYLEKEKEEMKSITE--ETRRQKEDLEKMSTHINEQKQDLRSQR 12305
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVT-ELQEDLNKESKEKQD------LEKRVLELT 525
LE+ + K K+L + I+ + ++V+ + +EDL KE + K+D + +LE+
Sbjct: 12306 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK 12365
Query: 524 SKLE 513
+K E
Sbjct: 12366 TKAE 12369
Score = 98.2 bits (243), Expect = 3e-17
Identities = 142/710 (20%), Positives = 297/710 (41%), Gaps = 62/710 (8%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ ++ DR+ L+ + L+ + + + T + N+R L+ K+
Sbjct: 5727 EKEIIMKDRSQLDLRQSELDKQQTNMNDIMET--------------MKNERKQLDKDKEE 5772
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE--------- 2100
+E + + E ++ + +D+K + + + E +K LE + E
Sbjct: 5773 MEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKI 5832
Query: 2099 --------ATIATLNDELLNEKDD----------KKCIVEADKQALESKVSVFEAAIATL 1974
+ + +EL+ EK+ +K I++ K A ES ++ + + L
Sbjct: 5833 KEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL 5892
Query: 1973 NDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 1794
+ N K+ I N++ + + L+ +++ ++ ++ E + + A+I++
Sbjct: 5893 EEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREK 5952
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
+++LK + D E M ++ + V NL+ ++ L + ++ K
Sbjct: 5953 -QNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLK 6009
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV---LERSASNLAIM 1443
D+ A + A + K + +E + R EE ER N I
Sbjct: 6010 LDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIE 6069
Query: 1442 KAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---------VLERRASNLDT 1305
+ R++ + EK+ ++ + + E E+ LEKT LE++ N T
Sbjct: 6070 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN--T 6127
Query: 1304 MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEPTIPSLNDALQRDLDRV 1131
+ I +E EK++++ E E E+Q +K + L+ I +L L+++ + +
Sbjct: 6128 LAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 6187
Query: 1130 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----K 969
M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D +
Sbjct: 6188 MKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSR 6247
Query: 968 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 789
+S+ DL +K ++QV E + + +E L E + E NER LE + + L+
Sbjct: 6248 KSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELK 6307
Query: 788 KRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILTDKAK 639
K + E+ H E T K+ + NE A+ Q K + E+ E IS T+ +
Sbjct: 6308 K---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVE 6363
Query: 638 KLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 489
+++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 6364 NKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 6410
Score = 94.7 bits (234), Expect = 3e-16
Identities = 125/616 (20%), Positives = 275/616 (44%), Gaps = 31/616 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGD-------FEAAIATLNDELLNEKDDKKCIVNDRNIVEA 2139
S+ + ++ K+ L+ + D FE I + EL E ++ I + +E
Sbjct: 2366 SLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAEN---IERKKKELEI 2422
Query: 2138 DKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDE-- 1965
K A+ + E + +E D+ + + AD +E + S ++ E
Sbjct: 2423 QKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEES 2482
Query: 1964 -LLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1800
+ EKD K N++N+ L A + L+ + A++E K L + ++R + + I K
Sbjct: 2483 YVKKEKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITK 2542
Query: 1799 KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1620
+ +R+++++ + +++ D+ + ++E + IL+ EL+K
Sbjct: 2543 EK--QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEK 2588
Query: 1619 EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMK 1440
K+ KT L ++ A + K + + + L L ++E E E+ ++ +
Sbjct: 2589 IKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDR 2642
Query: 1439 AIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD 1260
EE + K ++ K + + + E+ L + +R S+ DT++ +L K K +
Sbjct: 2643 RNNEEMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTE 2700
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK 1080
L + + E Q + + +E I + L++ + +K+ LEK E +
Sbjct: 2701 MKDLEK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKE 2753
Query: 1079 NASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSD 900
A ++ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E +
Sbjct: 2754 KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 899 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDD 726
+E + ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D+
Sbjct: 2814 IE----QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDE 2866
Query: 725 DYN--------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDL 579
+ N E+++ TL+K +L++ + + D K+L + I L+E+ + +E L
Sbjct: 2867 EANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREIL 2926
Query: 578 NK----ESKEKQDLEK 543
+ SK+K+DLEK
Sbjct: 2927 EQLKLTLSKQKEDLEK 2942
Score = 94.4 bits (233), Expect = 4e-16
Identities = 147/772 (19%), Positives = 322/772 (41%), Gaps = 64/772 (8%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
K D++ + N++ +L+ K L+ + + E I DR L+
Sbjct: 3670 KQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMN 3729
Query: 2258 QALENKVGDF---EAAIATLNDELLNEKDD----KKCIVNDRNIVEADKQALENKVADFE 2100
+ ++ D E + DEL K + ++ + ++ I+ D+ L+ K ++ +
Sbjct: 3730 DNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELD 3789
Query: 2099 ATIATLNDELLNEKDDKKCI------VEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ND + K+++K + +E K+ +E + F+ +L+++L K K+
Sbjct: 3790 KQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQ 3849
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
++N LE K LE + ++ K + +E +++L+K +LK
Sbjct: 3850 VFEEEKNKLEQMKIELEREAGEIRKIKEEIQNE------------RQSLEKMTEELK--- 3894
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
R++E + +I+ ++V L ELQKEK + + +++
Sbjct: 3895 --REKESFTHLA--------EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK 3944
Query: 1577 AEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERS------ASNLAIMKAIREEELR 1416
+ E + E + L+ +++ + E+S A+ + I++ ++ + +
Sbjct: 3945 QTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIIS 4004
Query: 1415 KEKDGKSALVENGEGCEAEKQGLE--KTVLERRASNL----------------------- 1311
++D +S ++ E E E++ L+ KT LER +
Sbjct: 4005 LDRDAESLKLDR-EAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITK 4063
Query: 1310 --DTMDAIHEEELRKEKV--DKS--------ALTENGEGCEAEKQGPEKTVLDLEPTIPS 1167
D ++ + EE RK+ V +K+ ++ + + E EK EKT +L
Sbjct: 4064 ERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELY----K 4119
Query: 1166 LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELH 987
+ + L++ + +AE ++K DLE N ++T +E + H +E
Sbjct: 4120 VKEDLEKQKENTLAE---IQKEREDLEKMNENIT-------------IEMHEIKHQEEQM 4163
Query: 986 KEKDD-----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER 822
K+K D K I N ++ E++++ S+++ S L+ + D E NER
Sbjct: 4164 KQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 4223
Query: 821 DGLEAVKQGLEKRVLDLEATIHDIEMK-TGKDDDYN--EAEKQTLKKRISELEEAISILT 651
L+ K+ +E++ ++E +++ D+D + +KQ +++ ++LE+ L
Sbjct: 4224 KLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4283
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIK 471
+A ++ K +E L++ KE++DL + E T + ++ + D +
Sbjct: 4284 READEIRKIKEETQNERQSLEKMTKALIKEREDL-VHLAEYTKREKEML----DEMQVAN 4338
Query: 470 EAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISEDSTTNIQVD 315
++ M+D + E++ + S++T DI + + ED +Q +
Sbjct: 4339 KSSMADLQREKRIL--EEMRENISKQTE--DIENEKEKSKLREDELKKLQTE 4386
Score = 94.4 bits (233), Expect = 4e-16
Identities = 139/601 (23%), Positives = 252/601 (41%), Gaps = 10/601 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR-------NIVEADKQAL 2124
+N +E K+ L+N + E + +L E N +D+K + R N + +++ L
Sbjct: 9653 KNQIEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDL 9712
Query: 2123 ENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVF--EAAIATLNDELLNEK 1950
EN + E + +E + ++ I + D + +S+ ++ E I +ELL K
Sbjct: 9713 ENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMK 9772
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL 1770
+ + + +E Q L+ DLE AK E++R++D II + ++ ++
Sbjct: 9773 VE---MGRTKEEIEKESQRLQDATIDLENAKA----EIQRQEDKFEDIIDIKIQEKEREI 9825
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1590
K Q D+E + V +LE+ + + + Q+ +D K L K
Sbjct: 9826 KI---QLDKETKRLS------------EEIELKVKDLEMEMADMKRQKQEIEDTKGLLEK 9870
Query: 1589 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ K+ + + LE + L RE+++ ER+ NL +K + E+LRKE
Sbjct: 9871 E-------KQELKQEKKELEDQMMDLT----REKQETEEERN--NLMALKN-QLEDLRKE 9916
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ EK LEK+ +E + ++++ + K +K +L +
Sbjct: 9917 NE-----------IVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRFE 9965
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
E +KQ E + + + D L R+L + K LEK + N+E
Sbjct: 9966 TEQQKQMLEISTTKMMEEKNEMAD-LSRELQKA---KDELEK---------IAYKTNKER 10012
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 870
HE E +++A ELH + + ++ + Q+++ K + +E ++
Sbjct: 10013 HEVE---QMQA-------ELHSQ----------IQAIEQQGQIMQDKQNHLEEKELSIQR 10052
Query: 869 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKK 690
+ ++ N F E++ L V + KR DLE DIE+ K N + + L+K
Sbjct: 10053 KEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEK 10108
Query: 689 RISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLE 513
SELE D+ IW + L E L + KEK+ LEK +EL SK E
Sbjct: 10109 IRSELENE-----------KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKRE 10157
Query: 512 K 510
+
Sbjct: 10158 Q 10158
Score = 94.4 bits (233), Expect = 4e-16
Identities = 135/648 (20%), Positives = 285/648 (43%), Gaps = 52/648 (8%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVE--------- 2142
I +RN LE K L + E + L+ ++ +K I ++ IVE
Sbjct: 10464 IEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQ 10523
Query: 2141 -------ADKQALENK-VADFEATIATLNDELLNEKDDKKCIVEADK------QALESKV 2004
++ ALE + + D + +A EL N+ + + + EA K + E+ +
Sbjct: 10524 RNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHL 10583
Query: 2003 SVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN---DELE 1833
+ I ++ +E +K+D + I N+ KQ L+ K LE + +N + +
Sbjct: 10584 QRDKKEIKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQ 10640
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1653
++ D+ +A ++K ++ +++ K +R +++N I ++
Sbjct: 10641 QRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHE---INQKIE 10697
Query: 1652 NILILHEELQKEKDDKTAL-IKDLVAAEPGKRTVNEIV---SHLESKSRSLKEHF-LREE 1488
+ L E++ KEK+ A+ IK + E + +E+V + ++ + + L + + E+
Sbjct: 10698 ELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQ 10757
Query: 1487 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1308
E E LE+ S + K E+E R E D K + + EK +EK+ +
Sbjct: 10758 EKEDLEKMKSEIMTQKQEMEKE-RSELDNKI------QQTDLEKHDIEKSKEIVEKLMFE 10810
Query: 1307 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL--------DLEPTIPSLNDAL 1152
+ HE +L+KE++D E +K E+ +L + I ++N+ +
Sbjct: 10811 VEEQRHEIQLQKEELD----------IERQKIADEQDLLIQNKSELQNENERIRNINEVI 10860
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 972
+++ + + + LEK +++ S+T+ + ++E K+ N +L K++D
Sbjct: 10861 KKERETLKEMEAHLEKEKEEMK----SITEETRRQKEDLE-KMSTDIKEQNQDLMKQRDL 10915
Query: 971 KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 792
E D++H E L+ ++ + + + ++ + ++ + + ER LE K
Sbjct: 10916 LEQEKEDINH---EWTQLQQRIDEFD---AQVSKQKEEDLTKQKEMKEERKSLEETK--- 10966
Query: 791 EKRVLDL--EATIHDIEMKTGKDDDYN------EAEKQTLKKRISELEEAISILTDKAKK 636
R++++ +A + DI+ + K+++ E + + L + SEL+ S + + KK
Sbjct: 10967 -ARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKK 11025
Query: 635 LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK-----LEKC 507
L D I E L++ ++ K++Q +E+ EL +K +EKC
Sbjct: 11026 LNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKC 11073
Score = 92.8 bits (229), Expect = 1e-15
Identities = 132/673 (19%), Positives = 297/673 (44%), Gaps = 31/673 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENK-------VGDFEAAIATLNDELLNE----KDDKKCIVNDR-N 2151
++N R++LE ++ + +K + +F+A ++ ++ L + K+D+K + + N
Sbjct: 11187 LMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 11246
Query: 2150 IVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN 1971
++E +A ++ + N+E E+++ + IVE +++ L S E + ++
Sbjct: 11247 VIEMKTKAEPEEIKKEKEKE---NEEEEEEEEEIRVIVETERKELYQIKSELERVRSEID 11303
Query: 1970 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE-----LERKKDDNNAI 1806
E D K I ++ LE K + + +E ++ L+++ LE+ + +
Sbjct: 11304 HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKE 11363
Query: 1805 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1626
I + L + + + D + +E D+ E N+L+ ++
Sbjct: 11364 IVEKLMVEVEEQRKDIQLQKEELDIERQKIAD-----------------EQNLLVQNKAK 11406
Query: 1625 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS---RSLKEHFLREEEDEVLERSASN 1455
+ ++++ + + + E + T+ E+ HL+ + RS+ E R +ED LE+ +++
Sbjct: 11407 LQNENERIKKVDEEIKKE--RETLREMEIHLKKEKEELRSIIEETQRRKED--LEKMSTD 11462
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR 1275
+ K L+ ++D L+E E E+ E T L++R D + E+L
Sbjct: 11463 INEQKL----HLKNQRD----LLEQ----EREEINHEMTQLQQRIDEFDAQVSKQREDLT 11510
Query: 1274 KEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCS 1095
K+++ E E++ E+T + + + +L +M EK+ ++
Sbjct: 11511 KQEM------------EEERKSLEETKARI------IEMKTKAELQEIMQEKEEEDEE-- 11550
Query: 1094 DLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLE 915
E + + +E ++ + E K S + H E K DDK+ I + + ++ + +
Sbjct: 11551 --EMRVIVEMEREELNQIKSELKRVRSEIDH--EQKKLNDDKKIIEQEKEDLEKMKSEIM 11606
Query: 914 SKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 735
++ ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 11607 TQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQ 11666
Query: 734 KDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
K D N+A+ Q +RI E++E I K K+ LK++ L + E + +
Sbjct: 11667 KIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSVIE 11722
Query: 572 ES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFS 399
E+ ++K+DLEK ++ +K + + RD L +E + W + + F
Sbjct: 11723 ETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDEFD 11775
Query: 398 RKTSPL---DITK 369
+ S D+TK
Sbjct: 11776 AQVSKQKEEDLTK 11788
Score = 92.8 bits (229), Expect = 1e-15
Identities = 128/675 (18%), Positives = 276/675 (40%), Gaps = 35/675 (5%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N R++LE ++ + +++ + I + ++ +++D + + + E K E K
Sbjct: 11472 NQRDLLEQEREEINHEMTQLQQRIDEFDAQVSKQRED----LTKQEMEEERKSLEETKAR 11527
Query: 2108 DFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEKDD 1944
E E++ EK+++ + IVE +++ L S + + ++ E DD
Sbjct: 11528 IIEMKTKAELQEIMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDD 11587
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDKRI 1779
KK I ++ LE K + + +E ++ L++ +LER +N+ I + L ++
Sbjct: 11588 KKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKV 11647
Query: 1778 SDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTA 1599
+ + D + +E D+ E QK D++
Sbjct: 11648 EEQRKDIRLQKEELDI---------------------------------ERQKIADEQGL 11674
Query: 1598 LIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
++++ + + E+ ++ + +LKE E L
Sbjct: 11675 VVQNKAKLQNENERIKEMDEEIKKEKETLKE------------------------MEAHL 11710
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---DAIHEE-----------E 1281
RKEK+ +++E E +K+ LEK + N D M D + +E +
Sbjct: 11711 RKEKEEMRSVIE--ETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQ 11768
Query: 1280 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1101
R ++ D + E +K+ E+ E I + + + +++ EK+ E+
Sbjct: 11769 QRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEE- 11827
Query: 1100 CSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV 921
E A + +E + +I+ +LE + E K DDK+ I + + ++ +
Sbjct: 11828 ----EVMRAKVEMKKEELD-QIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSE 11882
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
+ + ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 11883 IMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIE 11942
Query: 740 TGKDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 579
K D N+A+ Q +RI E++E I K K+ LK++ L + E +
Sbjct: 11943 RQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSV 11998
Query: 578 NKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQG 405
+E+ ++K+DLEK ++ +K + + RD L +E + W + +
Sbjct: 11999 IEETQRRQKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDE 12051
Query: 404 FSRKTSPL---DITK 369
F + S D+TK
Sbjct: 12052 FDAQVSKQKEEDLTK 12066
Score = 91.7 bits (226), Expect = 3e-15
Identities = 140/737 (18%), Positives = 310/737 (42%), Gaps = 97/737 (13%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ +V+++ +L + L+NK + D+ +++ +
Sbjct: 10537 ERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEE 10596
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N + K+ K + +R + + ++ +F+A + +E
Sbjct: 10597 TSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEE 10656
Query: 2072 -LLNEK---DDKKCIVEADKQALESK---------VSVFEAAIATLNDELLNEKDDKKCI 1932
L N+K +++KC+ E + + +E K ++ + TL ++++ EK+ + +
Sbjct: 10657 DLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAM 10716
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADA 1758
L+ ++ L+ ++L KT ++ E ++ DD I K+ L+K S++
Sbjct: 10717 TIK---LKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10773
Query: 1757 PQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD------KTA 1599
+ ++E +++ I +IV L + E+Q +K++ K A
Sbjct: 10774 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIA 10833
Query: 1598 LIKDLVAAEPGK--------RTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIM 1443
+DL+ + R +NE++ + ++ H +E+E+ M
Sbjct: 10834 DEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEKEE------------M 10881
Query: 1442 KAIREEELRKEKDGKSA----------LVENGEGCEAEKQGL--EKTVLERRASNLDTM- 1302
K+I EE R+++D + L++ + E EK+ + E T L++R D
Sbjct: 10882 KSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQV 10941
Query: 1301 ------DAIHEEELRKEKVD----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
D ++E+++E+ K+ + E E E EK + E + +
Sbjct: 10942 SKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 11001
Query: 1151 QRDLDRVMAE-------------------------KQALEKRCSDLEAKNASLTDNQEGH 1047
++LDR+ +E KQ LEK S++ + + + +
Sbjct: 11002 GKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSEL 11061
Query: 1046 EAEIERK-LEASNLTHNDELHKE-----KDDKESIMNDLDHVKAERQVLESKVSDMETTY 885
E +I++ +E ++ ++ E+ ++ ++ K I + + ERQ + + +
Sbjct: 11062 ENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11121
Query: 884 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------D 723
S L NE ++ + NE ER+ L+ ++ LEK+ ++++ E + K+D D
Sbjct: 11122 SELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSE--ETRRLKEDLEKMSTD 11179
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQD-- 552
N+ K + +R LE+ + K K+L + I+ + ++V++ +E DL KE K+D
Sbjct: 11180 VNKQNKDLMNQR-DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRK 11238
Query: 551 ----LEKRVLELTSKLE 513
+ V+E+ +K E
Sbjct: 11239 SLEETKANVIEMKTKAE 11255
Score = 91.3 bits (225), Expect = 4e-15
Identities = 146/692 (21%), Positives = 284/692 (41%), Gaps = 60/692 (8%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQAL---ENK 2241
+R LE LE K + + I +NILE K L + +
Sbjct: 13840 ERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQ 13899
Query: 2240 VGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNE 2061
V + + T+ + +E ++ +C+ RN +E +K+++ ++++ + I L E+ +E
Sbjct: 13900 VQQQKHEMETIRKTMKSEMENLECL---RNELEDEKKSMLSRLSMEKHEIDKLKTEIQSE 13956
Query: 2060 KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYK 1881
K+ +E +K+ L+ E+ L++ + DK I +++ LE K L+ K
Sbjct: 13957 KES----IEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRK 14012
Query: 1880 VADLE-----AAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIX 1716
L+ A + T + K D++ ++ L +D++ A + E D+ L
Sbjct: 14013 AEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQA--KILESDVQLLQT 14070
Query: 1715 XXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNE 1548
+ +LE N L L +EL+KEK +I D+ + +
Sbjct: 14071 EKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------D 14122
Query: 1547 IVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGE 1374
V+ L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 14123 AVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENM 14181
Query: 1373 GCEAEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTE 1242
+ + ++ + E R D + DA+ + +EL K D E
Sbjct: 14182 KMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKE 14241
Query: 1241 NGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA---- 1083
+ E E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 14242 HVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADD 14301
Query: 1082 --------KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH 942
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 14302 IKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQ 14361
Query: 941 ---------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGL 792
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +
Sbjct: 14362 KEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 14421
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 612
E +EKQ++++ +EL K+L +++ +
Sbjct: 14422 E-------------------------SEKQSIERERAEL-----------KRLKEEVEVQ 14445
Query: 611 LSEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
E T LQ+D N KEK+ LE T ++
Sbjct: 14446 -HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 14476
Score = 90.1 bits (222), Expect = 8e-15
Identities = 141/644 (21%), Positives = 275/644 (42%), Gaps = 49/644 (7%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN- 2118
I NDR E L+N+ D E + + DE N + K+ + +DR+ +E ++ LE
Sbjct: 2638 IDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKT 2697
Query: 2117 --KVADFEATIATLND-------ELLNEKD---DKKCIVEADKQALESKVSVFEAAIATL 1974
++ D E + + + E+ E++ K + K+ LE + FE A +
Sbjct: 2698 KTEMKDLEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1973 N-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERK--KDDNNAI- 1806
+ E L E+ +K+ I D+ + ++ E + L K N+EL+++ +D+ + I
Sbjct: 2758 SLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE 2815
Query: 1805 -IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1638
IK L K D + ++D E+D ++ + + E N+ +L
Sbjct: 2816 QIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVL 2873
Query: 1637 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSA 1461
+ L+ ++D L K+ + + ++ LES++R + ++E E+LE+
Sbjct: 2874 KQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1460 SNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1290
L+ K E+E KEK S E E ++E++G+ KT R MD
Sbjct: 2931 LTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIKKEMD--- 2981
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL 1110
EL++ +++ EN E +KQ ++ + D++ K L
Sbjct: 2982 --ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKIEQIKAEL 3018
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDKESIMNDL 948
+K D E + + ++ +E + ++ +E S DE + K+ + +D
Sbjct: 3019 QKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDR 3078
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
D ++ ER LE ++M L ++++Q ER+ LE +K L K+ DLE
Sbjct: 3079 DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLE 3138
Query: 767 ATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL------TDKAK 639
E + +D ++E++ +K+ + ELE+ L + K
Sbjct: 3139 KERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQK 3198
Query: 638 KLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 510
K+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3199 KIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 89.0 bits (219), Expect = 2e-14
Identities = 139/671 (20%), Positives = 284/671 (42%), Gaps = 55/671 (8%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R I+E ++ L + + + ++ E DDKK I ++ +E K + +
Sbjct: 11553 RVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQM 11612
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALES---KVSVFEAAIATLNDELLNEK----DD 1944
E + L D + + D ++ +E K+ ++ KV I +EL E+ D+
Sbjct: 11613 EEERSEL-DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADE 11671
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISD 1773
+ +V ++ L+ + ++ +++ K TL + L ++K++ ++I++ ++ D
Sbjct: 11672 QGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKED 11731
Query: 1772 LK---ADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
L+ D +++Q+ L+ + L+ I ++ K+K++
Sbjct: 11732 LEKMSTDVNKQNQD-----LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED- 11785
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE---EEDEV-----------LERS 1464
L K E K + +E K+++ E +E EE+EV L++
Sbjct: 11786 -LTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQI 11844
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIH 1290
S L +++ + E +K D K + + E E K + ++ +E S LD + I
Sbjct: 11845 KSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELD--NKIK 11902
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDLEPT--------IPSLNDALQR 1146
+ +L + ++ S E E+Q + K LD+E + LQ
Sbjct: 11903 QTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQN 11962
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ +R+ + ++K L+ A L +E E+ +E + ++L K D
Sbjct: 11963 ENERIKEMDEEIKKEKETLKEMEAHLRKEKE----EMRSVIEETQRRQKEDLEKMSTDVN 12018
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
+ +MN D +K ER+ + K + +LQQ++D+ +A ++++ + KQ
Sbjct: 12019 KQNQDLMNQRDLLKQEREEINHKWT-----------QLQQRIDEFDAQVSKQKEEDLTKQ 12067
Query: 797 G-LEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD 624
+E+ LE T I IEMKT + + + EK+ E EE + + K+ L
Sbjct: 12068 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE------KEEEEVMRAKVEMKKEELDQ 12121
Query: 623 INIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I L SE+ Q+ LN + K EK+DLEK E+ + ++ + + I++
Sbjct: 12122 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 12181
Query: 467 AWMSDCMVPDN 435
++ C + ++
Sbjct: 12182 TYIEKCDIENS 12192
Score = 88.2 bits (217), Expect = 3e-14
Identities = 144/674 (21%), Positives = 290/674 (43%), Gaps = 38/674 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
K + VV + E KQ +E++ E A + I DR E
Sbjct: 2984 KQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMV 3043
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD--------------KQALE 2121
L+N+ D E + + DE N + K+ + +DR+ +E + K+ LE
Sbjct: 3044 IKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLE 3103
Query: 2120 NKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN-DELLNEKDD 1944
+++ E + + E + K + K+ LE + FE A ++ E L E+ +
Sbjct: 3104 SQIRQHEIQLVEIQKER-EILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSE 3162
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKA 1764
++ I N R ++ LE +L AK N+EL++K II+ DK I +KA
Sbjct: 3163 REGIDNTRTRIKQEMDELEKTRQNL--AKEQENNELQKK------IIEDERDK-IEQIKA 3213
Query: 1763 DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+ + ++ + + N N+ +L+K++++ +L ++L
Sbjct: 3214 ELKKEAEKTKLE-------------------LQNERQNLEEAGTKLKKDRENVESLAEEL 3254
Query: 1583 VAAE---PGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRK 1413
+ + E+ ++ ++E L E L+++ +++A K E +L +
Sbjct: 3255 GRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTDIAGAKEDLENQLLE 3309
Query: 1412 EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-EELRKEKVDKSALTENG 1236
E++ V+ E +AEK L L ++ + +D +++ E+LR +V+ L
Sbjct: 3310 EREKNK--VKQAE-IQAEKDML---YLLKQGISEQQVDIVNKTEQLRLREVELEQLQALI 3363
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMA----EKQALEKRCSDLEAKN 1077
+ E + K +++ + + D LQR+++++M ++ LEK S++ A+
Sbjct: 3364 YRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSEMIAQK 3423
Query: 1076 ASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDM 897
+ IE + + N T+ E+ +++ E M +L + K Q ++K+ M
Sbjct: 3424 HQMDIELNKERGLIEERTQMLN-TYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQM 3482
Query: 896 ETTYSTLNNELQQKMDD----NEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
+ ELQ++ DD E NER LE + + LEK DL D + K +
Sbjct: 3483 KI-------ELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLAEDTKRKDDEM 3535
Query: 728 DDYNE---AEKQTLKKRISELEEAI-----SILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+E A+ Q K + ++ E++ I ++K K +L++ ++ ++Q ++N+
Sbjct: 3536 KVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILRE-----DKLQQMQAEINR 3590
Query: 572 ESKEKQDLEKRVLE 531
+ E D +K ++E
Sbjct: 3591 QQTE-MDTKKSIIE 3603
Score = 88.2 bits (217), Expect = 3e-14
Identities = 131/622 (21%), Positives = 266/622 (42%), Gaps = 27/622 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVG-------DFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD 2136
I+ R +E + L+NK+ D E + + ++ ++ +K I + ++ +
Sbjct: 11330 IMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIE 11389
Query: 2135 KQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLN 1956
+Q K+AD + + +L NE + K + E K+ E+ + + L
Sbjct: 11390 RQ----KIADEQNLLVQNKAKLQNENERIKKVDEEIKKERET--------LREMEIHLKK 11437
Query: 1955 EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDK 1785
EK++ + I+ + + K+ LE D+ K L ++ LE+++++ N + + L +
Sbjct: 11438 EKEELRSIIEET---QRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQ-LQQ 11493
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
RI + DA Q +D+ I + + + +E ++E +++
Sbjct: 11494 RIDEF--DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEE 11551
Query: 1604 TALIKDLVAAEPG--KRTVNEIVSHLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAI 1434
+I ++ E K + + S ++ + + L + + E+E E LE+ S + +
Sbjct: 11552 MRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQ 11611
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
EEE R E D K +++T LER +++ I ++ + K + +
Sbjct: 11612 MEEE-RSELDNK----------------IKQTDLERH--DIENSKEIVQKLMVKVEEQRK 11652
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 1074
+ E + E+Q + D + + LQ + +R+ + ++K L+ A
Sbjct: 11653 DIRLQKEELDIERQ----KIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEA 11708
Query: 1073 SLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KESIMNDLDHVKAERQVLESKV 906
L +E E+ +E + ++L K D + +MN D +K ER+ + K
Sbjct: 11709 HLRKEKE----EMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKW 11764
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG-LEKRVLDLEAT-IHDIEMKTGK 732
+ +LQQ++D+ +A ++++ + KQ +E+ LE T I IEMKT
Sbjct: 11765 T-----------QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKT 11813
Query: 731 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKESK 564
+ + + EK+ E EE + + K+ L I L SE+ Q+ LN + K
Sbjct: 11814 EPEKIKKEKE------KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKK 11867
Query: 563 ----EKQDLEKRVLELTSKLEK 510
EK+DLEK E+ + ++
Sbjct: 11868 MIEQEKEDLEKMKSEIMKQRQQ 11889
Score = 87.8 bits (216), Expect = 4e-14
Identities = 143/649 (22%), Positives = 278/649 (42%), Gaps = 45/649 (6%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEA---AIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N+++ ++ E K + + A+ +N EL + + K + + EAD Q +NK
Sbjct: 13821 NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTE 13880
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
+ + + EL EK V+ K +E+ ++ + L + L NE +D+K +
Sbjct: 13881 ELKNILEREKSELYQEKAQ----VQQQKHEMETIRKTMKSEMENL-ECLRNELEDEKKSM 13935
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDKRISDLKADA 1758
R L K ++ ++++ K ++ +E L++ KD+N + + LD I + D
Sbjct: 13936 LSR--LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENES-KRTQLDNTIEKMNMDK 13992
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
+E D +I ++L+ L EE++K + + +D
Sbjct: 13993 LSIQREKD----------------SLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKI 14036
Query: 1577 AEPGKRTVNEIVS---HLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ + E+ S +E +++ L+ L + E E+LE+S + +++ E+L K+
Sbjct: 14037 LDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLR----EDLEKQ 14092
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ ++ EK LE+ + + D + ++ E K+ K+ TE E
Sbjct: 14093 RKRNDLTLQE---LRKEKMALEQMITD-ITKEKDAVASLQNEVSLKQHELKNKETELDE- 14147
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+++ + + LE S N Q+++D + E K +DLE+ L + +
Sbjct: 14148 ---QRKEMDDLRMQLEMRQNSTNKQ-QQEVDVFIVENM---KMRNDLESMKTLLDEERRQ 14200
Query: 1049 HEAEIERKLEASNLTH---------NDELHKEKDDKESIMNDLDHVKAERQ---VLESKV 906
+ I+ + N+ H DEL K D I + +HV+ ER+ VL ++
Sbjct: 14201 LQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD---IKTEKEHVEKEREEIDVLNKEI 14257
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE--MKTGK 732
+ +LN E+ E F E G A + LE+ DL A DI+ ++T K
Sbjct: 14258 IKSKEELQSLNLEI-------EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEK 14310
Query: 731 DDDYNEAEKQT-------LKKRISELEEAIS-------------ILTDKAKKLLKDI-NI 615
+ EK+T L+K+ +ELEE + I+ DK +K ++DI +
Sbjct: 14311 QMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTV 14370
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
SE L+++ ++ +K L ++V +LE+ + RD + K+
Sbjct: 14371 IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKK 14419
Score = 87.4 bits (215), Expect = 5e-14
Identities = 127/646 (19%), Positives = 279/646 (43%), Gaps = 58/646 (8%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
++ KQ ++ K A+ L K+ ++ I ++ +E +K ++ + +
Sbjct: 10173 IQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKV 10232
Query: 2093 IATLNDELLNEKDDKKCIVEAD----KQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
+ E + + +K I EAD K+ E+ E + +++ N ++ K +
Sbjct: 10233 L-----EEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQ 10287
Query: 1925 DRNILEAAKQALEYKVADL-----------EAAKTTLNDELERKKDDNNAIIKKA--LDK 1785
+R ++ KQ L+ + DL E +K +L++E + + N I+++ L+K
Sbjct: 10288 ERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEK 10347
Query: 1784 RISDL-----KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE--- 1629
D+ K D Q + +++ A+ K LE ++ ++EE
Sbjct: 10348 EKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGD 10407
Query: 1628 ---LQKEKDDKTALIKDL-VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE-VLERS 1464
++ + + + I+++ V A+ ++ +++I S LE + + + D ++E+
Sbjct: 10408 LEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKE 10467
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDTMD--- 1299
++L MK+ + ++ +D +S L + + EK +EK ++ER + ++
Sbjct: 10468 RNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDF 10527
Query: 1298 AIHEEELRKEK---VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-------Q 1149
+ +EEL E+ VD+ L CE E Q + + ++E + + + L Q
Sbjct: 10528 KLKKEELALERQNIVDEKYLLAQ---CETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 10584
Query: 1148 RD-------LDRVMAEKQALEKRCSDLEAKNASLT---DNQEGHEAEIERKLEASNLTHN 999
RD ++ +K+ LEK + + + L D E EI K +
Sbjct: 10585 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 10644
Query: 998 DELHKEKDDKESIMNDLDHVKAERQVLES---KVSDMETTYSTLNNELQQKMDDNEAFLN 828
+ + + KE + + ++ ER+ LE K+ +M+T ++E+ QK+++
Sbjct: 10645 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEE------ 10698
Query: 827 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 648
L+ +++ + K EA ++M E++ L + SEL + +
Sbjct: 10699 ----LQTLQEQIMKEKEKAEAMTIKLKM-----------EREDLDQIKSELVREKTEVDH 10743
Query: 647 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
+ KKL DI + E +L++ ++ +KQ++EK EL +K+++
Sbjct: 10744 EQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 10789
Score = 85.5 bits (210), Expect = 2e-13
Identities = 144/713 (20%), Positives = 299/713 (41%), Gaps = 118/713 (16%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
++N R++L+ ++ + +K + I + ++ +K++ + + + E K E K
Sbjct: 11746 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED--LTKQKKMEEERKSLEETK 11803
Query: 2114 VADFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEK 1950
+ E T +++ EK+ + + VE K+ L+ S E + ++ E
Sbjct: 11804 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11863
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDK 1785
DDKK I ++ LE K + + +E ++ L++ +LER +N+ I + L
Sbjct: 11864 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMV 11923
Query: 1784 RISDLKADAPQRDQE---------DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
+ + + D + +E D+ ++ ++ ++ L E
Sbjct: 11924 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKE 11983
Query: 1631 ---ELQKEKDDKTALIK----------------------DLVAAEPGKRTVNEIVSHL-- 1533
L+KEK++ ++I+ DL+ + E ++H
Sbjct: 11984 MEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWT 12043
Query: 1532 --------------ESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGK 1398
+ K L + EEE + LE + + MK E E+++KEK+ +
Sbjct: 12044 QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE 12103
Query: 1397 SALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEE--------LRKEKVD---- 1260
V + E +K+ L+ K+ LER S +D HE++ + +EK D
Sbjct: 12104 EEEVMRAK-VEMKKEELDQIKSQLERVRSEID-----HEQKKLNDDKKMIEQEKEDLEKM 12157
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDL---EPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
KS + + + E E+ E + + I + + +Q+ + V +K ++ + +L
Sbjct: 12158 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 12217
Query: 1088 EAKNASLTDNQE---GHEAEIER------------KLEASNLTHNDE-LHKEKDDKESIM 957
+ + + D Q+ +++E++ K E L + L KEK++ +SI
Sbjct: 12218 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 12277
Query: 956 N-------DLD----HVKAERQVLESKVSDMETTYSTLNN---ELQQKMDDNEAFLNER- 822
DL+ H+ ++Q L S+ +E +N+ +LQQ++D+ +A ++++
Sbjct: 12278 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 12337
Query: 821 -DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDK 645
+ L K+ E R E + +EMKT + + + EK+ E E+ + + +
Sbjct: 12338 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEK-----EEEEQEMRVKVEM 12392
Query: 644 AKKLLKDINIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEK 510
+K ++ I L SE+ Q+ LN + K EK+DLEK E+ + ++
Sbjct: 12393 ERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQ 12445
Score = 84.0 bits (206), Expect = 6e-13
Identities = 125/589 (21%), Positives = 252/589 (42%), Gaps = 18/589 (3%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDEL-LNEKDDKKCIVNDRNIVEADKQALENKVADFE- 2100
+E KQ ++N+ + A L +E NE+ +++ + N + A + + DFE
Sbjct: 7414 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQKVN-QQKQATAFQMEKTDFER 7472
Query: 2099 --ATIATLNDELLNEKD-DKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
I N EL ++++ +KK I E K+ TL + N + I
Sbjct: 7473 IKTEIDQANKELADQQEKNKKTITEMQKER------------ETLEEMRANISKQVETIT 7520
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA-LDKRISDLKADAPQ 1752
N+ L + + L D+ L + E + N +++ LD+R SD+ D Q
Sbjct: 7521 NENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQ 7572
Query: 1751 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAE 1572
++ +D M+ ++N+E L + + + K D +L + A E
Sbjct: 7573 KEVDDLMD--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACE 7618
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
+ +NE +E + L ++ ++D++ ++R NL + K + E ++ + K
Sbjct: 7619 QLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKI 7678
Query: 1394 ALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGE 1233
+L G + +EK E+ ++E A+ LD + E + +E++D++
Sbjct: 7679 SLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKT 7738
Query: 1232 GCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE 1053
+ EKT DL+ T +N D + + ++ L K
Sbjct: 7739 YYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK----------------- 7775
Query: 1052 GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 873
E E +++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + +
Sbjct: 7776 --EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMM 7830
Query: 872 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ--- 702
E + D E NE+D L+ ++ ++K + +L+ E + + N+ +Q
Sbjct: 7831 KEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTE 7884
Query: 701 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 561
+K + L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7885 EIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7933
Score = 84.0 bits (206), Expect = 6e-13
Identities = 115/623 (18%), Positives = 262/623 (42%), Gaps = 6/623 (0%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
+ L E+ ++ K ++++ I +++ Q L + + L E+ N K DK +
Sbjct: 9072 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNL 9131
Query: 2039 VEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA 1860
E K LE K E+ L E + KK I ++ +E +++ +E ++ + E
Sbjct: 9132 -EKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVK 9190
Query: 1859 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 1680
T ++++ K++ + ++ L K+ + + D + M L
Sbjct: 9191 GFT---DVQKYKEELQIVTEELLTKKRN---LEQLNSDVQHLMQTLEEVDIQYIKKKAEL 9244
Query: 1679 XKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF 1500
I S ++ IL E+ +K+ ++ +I+++ + ++N + KE+
Sbjct: 9245 EHITSEIQKREQIL-EKQKKKLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENL 9303
Query: 1499 LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRA 1320
RE+++ L R EL++++D VE+ ++ K ++ +
Sbjct: 9304 RREKQETELFRG-------------ELQRQRDE----VESSRQALIMEKDQFKLKIDHQR 9346
Query: 1319 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1140
+ + A +E R E ++ + + E+ + +E + + + L ++
Sbjct: 9347 NEMSA--AFEKEHKRLENMENDLENQRAKLAESLNDAAK-----MEQKLQQMKNELNKEK 9399
Query: 1139 DRVMAEKQALEKRCSDLEAKNASLTDN----QEGHEAEIERKLEASNLTHNDELHKEKDD 972
++V KQ ++ +E + + ++GHE ++++K E + D+L ++ +
Sbjct: 9400 EQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANS 9453
Query: 971 KESIMNDLD-HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG 795
+ + DL ++ +RQ +E ++MET +L+ ++ DD N+RD E
Sbjct: 9454 ESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTH 9513
Query: 794 LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 615
LE + +L D+E K + + +E K+ ++ + LE + K + K++
Sbjct: 9514 LELKREELVRETEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMEN 9573
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPD 438
SE +L ++ +LE RV +E L++ + + E MS+ + +
Sbjct: 9574 VHSERQKLLLLQGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTE 9631
Query: 437 NWVPFEDLVQGFSRKTSPLDITK 369
+ L++ R+ L+I+K
Sbjct: 9632 Q-NEYRKLIEELQREKEQLEISK 9653
Score = 84.0 bits (206), Expect = 6e-13
Identities = 140/656 (21%), Positives = 289/656 (44%), Gaps = 72/656 (10%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
IA + D+LL EK+D + N + + +++++ D + + N +LL K +
Sbjct: 13675 IADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTE---- 13730
Query: 2039 VEADKQALESKVSVFEAAIATLNDELL---NEKDDKKCIVNDRNILEA-AKQALEYKVAD 1872
++ ALE + + +N ++ E++ + ++ + E A+ ++ + D
Sbjct: 13731 IQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 13790
Query: 1871 LEAAKTTL----------NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMN 1728
+E+ K L N EL+ + ++ +IKK ++ + K + QR+++ + MN
Sbjct: 13791 IESVKVRLVTESNQIDKMNSELKTRSEELENLIKK--QQKEFETKENEMQRERKALEKMN 13848
Query: 1727 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG-----K 1563
A + + N + + +LQKEK +KT +K+++ E K
Sbjct: 13849 AELERKSTE----------LKNKIEKVTVWEADLQKEK-NKTEELKNILEREKSELYQEK 13897
Query: 1562 RTVNEIVSHLESKSRSLKEHF-----LREEEDEVLERSASNLAIMK-------------- 1440
V + +E+ +++K LR E ++ + S L++ K
Sbjct: 13898 AQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQSEK 13957
Query: 1439 -AIREE-----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA------ 1296
+I EE +L+ E + K ++N EK ++K ++R +L+ + A
Sbjct: 13958 ESIEEEKKTLKQLKDENESKRTQLDN----TIEKMNMDKLSIQREKDSLEEIKADLQRKA 14013
Query: 1295 -IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1119
+EE+RK S ++++ + + +++ E+ + + I L+ D+ + EK
Sbjct: 14014 EKLDEEMRKAVQITSQISQDAKILDDDRE-KEEELRSMRADIERQAKILESDVQLLQTEK 14072
Query: 1118 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
+ LEK S T+N E ++E++ + ++LT EL KEK E ++ D+
Sbjct: 14073 EILEK----------SKTENDLLRE-DLEKQRKRNDLT-LQELRKEKMALEQMITDITKE 14120
Query: 938 KAERQVLESKVSDMETTYSTLNNEL---QQKMDDNEAFLNER-DGLEAVKQGLEKRVLDL 771
K L+++VS + EL +++MDD L R + +Q ++ +++
Sbjct: 14121 KDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVEN 14180
Query: 770 EATIHDIE-MKTGKDDDYNEAEKQTLKKRISELEEAISIL----------TDKAKKLLKD 624
+D+E MKT D+ E++ L+ I E+ ++L TD+ +K D
Sbjct: 14181 MKMRNDLESMKTLLDE-----ERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 14235
Query: 623 INIWLSEVTELQED---LNKE-SKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I V + +E+ LNKE K K++L+ LE+ ++ I G R + ++++
Sbjct: 14236 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEI-EMFKQEIAGKRAQIESLEQ 14290
Score = 83.6 bits (205), Expect = 8e-13
Identities = 137/630 (21%), Positives = 251/630 (39%), Gaps = 35/630 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN 2118
++V + E KQ +E++ E A L E + + ++ I NDR E L+N
Sbjct: 2792 NVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQN 2851
Query: 2117 KVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ D E + + DE N + KQ LES E L KD +K
Sbjct: 2852 EKKDIETSTDRIRDEEAN--------LRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEK 2903
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+ + E ++ + LE K TL+ + E + + + K+ D IS +
Sbjct: 2904 QLESQNRQHEIQLAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKAD--ISLREELQ 2961
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNIL---ILHEELQKEKDDKTALIKD 1587
Q ++E + +V LE N L I+ +E K + K L K+
Sbjct: 2962 EQSEREGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKE 3021
Query: 1586 LVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSASNLAIMKAIREEELRKE 1410
E +R + E R+ +E ++ + E + +E S IR+EE E
Sbjct: 3022 AEDTEKQRRDI-------EKDRRNNEEMVIKLQNEKKDIETSTDR------IRDEEANLE 3068
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSA------- 1251
K L + + E E+ LEKT E I + E++ ++ K
Sbjct: 3069 VQ-KQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLK 3127
Query: 1250 --LTENGEGCEAEKQGPEKTVLDLEPT-----------IPSLNDALQRDLDRVMAEKQAL 1110
L++ E E E+ EK D+ + I + +++++D + +Q L
Sbjct: 3128 INLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNL 3187
Query: 1109 EKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
K + E + + D ++ E AE++++ E + L EL E+ + E L
Sbjct: 3188 AKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKL----ELQNERQNLEEAGTKL--- 3240
Query: 938 KAERQVLESKVSDMETTYSTLNN-----ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 774
K +R+ +ES ++ L N E+Q+K +++ + ER +E L+K V D
Sbjct: 3241 KKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTD 3295
Query: 773 LEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 603
+ D+E + ++ + N +AE Q K + L++ IS + + + E
Sbjct: 3296 IAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVE 3355
Query: 602 VTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ +LQ + ++ E + K ++ +LE
Sbjct: 3356 LEQLQALIYRQQDEIEANRKAIINEKYRLE 3385
Score = 82.0 bits (201), Expect = 2e-12
Identities = 121/660 (18%), Positives = 268/660 (40%), Gaps = 69/660 (10%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
RN +EA K +EN+ + + D + K ++ + +++ + L KV
Sbjct: 14340 RNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQRE 14399
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + L ++ ++ ++ K I+E++KQ++E + A + L +E + + ++ + D
Sbjct: 14400 QEELERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEE-VEVQHERTLLQQD 14454
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR-- 1749
+N+++ K+ LE + A L +E++RK + + + K+ KR + P+
Sbjct: 14455 KNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIE 14514
Query: 1748 -----DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+EDD+ ++ + +E+ K + + +++
Sbjct: 14515 IEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEET 14574
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
VA + V ++ L S+ + +++H L LA MK I + E + K
Sbjct: 14575 VATTAKQPIVIKLEDTLTSEVQEMRDH---------LNNEIKELARMKTIMKMEKDQLKQ 14625
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK--SALTENGEG 1230
KS + E E + +E+ + E+ + + H++E +DK + N E
Sbjct: 14626 AKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEIENNTET 14682
Query: 1229 --------------CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCS- 1095
+ +K+ E +L L+ +QR D EK+ ++ +
Sbjct: 14683 FLKKIAQLETTIVLMKKDKENIENELLQLKQI--EQEREIQRKADVTSTEKEMYTEKVTY 14740
Query: 1094 -------------------DLEAKNASLTDNQ---EGHEAEIERKLEASNLTHND--ELH 987
+L +++ TD + + E +++ L+ ++ T D ELH
Sbjct: 14741 KTELEDSKEKIKPDRDSTLELTDTDSAKTDGEREAQTLETKVQDVLQLTDDTTQDQEELH 14800
Query: 986 KEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE-------AFLN 828
E ++K I+ +L+ K + Q L+ + E S + L+++ + E +
Sbjct: 14801 DEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQ 14860
Query: 827 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISI 657
E D L +K +++ + ++ + + D + ++ ++ + EE IS
Sbjct: 14861 EIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISA 14920
Query: 656 LTDKAKKLLKDINIWLSEVTELQEDLNKESK-----------EKQDLEKRVLELTSKLEK 510
K + K + SEV E+++ LNKE + EK LE+ ++ +++E+
Sbjct: 14921 KKTKQPIVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEE 14980
Score = 77.8 bits (190), Expect = 4e-11
Identities = 127/620 (20%), Positives = 259/620 (41%), Gaps = 70/620 (11%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQA---LESKVSVFEA 1989
D+ + A+ Q L ++ + L E+ K+ I++ D++ L+ +V
Sbjct: 1361 DQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKE----IMKRDREEIRLLKIEVQRRRR 1416
Query: 1988 AIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD-NN 1812
I ++++ E+D+ + + + + ++ LE ++ ++ ND +E+ ++D NN
Sbjct: 1417 EIEYREEKIMREQDELELM---SKMGQRQREELEERLEEVIKE----NDRVEQMREDVNN 1469
Query: 1811 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
A+ K +D+ D++ QE A++ I S + L L
Sbjct: 1470 AL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKS-YRASDLELSA 1526
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 1452
+QKE+ + K+++ E K +N+I +++ +E ++ E+E E +
Sbjct: 1527 SIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKLHEEEK-EMKTKRV 1582
Query: 1451 AIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------EKTVLERR------ 1323
++ R+ + KEK+ G A+ + KQ L EK+ LE +
Sbjct: 1583 SLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIK 1642
Query: 1322 -------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE------- 1203
AS D +I E + +++ ++ + C E+Q E
Sbjct: 1643 QVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDE 1702
Query: 1202 ------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+T D+E + L++ D + K ++K DL+ + A +
Sbjct: 1703 LSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREK 1762
Query: 1058 QEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAERQVLESKVSDMET 891
+E E+E+ + N D E K E D K ++ + ++++A+R+++E + +E
Sbjct: 1763 EEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALEN 1822
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM------KTGKD 729
L E +ER +E + L++ +LE HD++ + KD
Sbjct: 1823 MKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKD 1882
Query: 728 -DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWLSEVTELQEDLNKE 570
++ E + TL K S++ E IS L + K +++ I I ++ ++Q DLN++
Sbjct: 1883 LENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQ 1942
Query: 569 SKEKQDLEKRVLELTSKLEK 510
KE QD++ V S+L+K
Sbjct: 1943 QKEMQDIQNAVFMEKSELKK 1962
Score = 76.6 bits (187), Expect = 1e-10
Identities = 135/691 (19%), Positives = 273/691 (39%), Gaps = 100/691 (14%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R ++E K+ALEN + + + N D+++ + N ++ + + LE K D
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + T + + ++ + + E +++K V E I+ LN + +KD+
Sbjct: 1870 QQ-LQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQ---QKDE------- 1917
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
+E K ++ + DL+ +T LN + + +D NA+ K L K ++ A Q
Sbjct: 1918 ---IENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQL 1971
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAE 1572
Q DM NL+ I+ ++LQ E+D L ++L + +
Sbjct: 1972 KQVGDMMQFTQNEK-------------DNLDRERAAIIEQKLQMERDMTHLLNRELESLK 2018
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
K+ V LE SL E+ ++ LER + + + EE K +
Sbjct: 2019 LVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQ 2078
Query: 1394 ALVENGEGCE----AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK---------- 1257
L E+ E AEKQ LE +E + + M+ E + ++E VDK
Sbjct: 2079 TLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEI 2138
Query: 1256 ------------SALTENGEGC---------------EAEKQGPEKTVLDLEPTIPSLND 1158
+A+ EN + E+Q ++ V ++E +L D
Sbjct: 2139 TFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-D 2197
Query: 1157 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER----KLEASNLTHNDEL 990
+Q ++D+ E+Q +E + +LE + + L ++++ + E+ + E + N EL
Sbjct: 2198 EMQMEVDK---ERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLEL 2254
Query: 989 HKEKDDKESIMNDLD---------------------------------HVKAERQVLESK 909
E KE + +L+ ++A++ K
Sbjct: 2255 QSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKK 2314
Query: 908 VSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
++T L+++ + E+ E + +E K+ + ++ E+ + +EM+
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM 2374
Query: 728 DDYNEA----------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV------T 597
Y E ++Q +K I ++ + I + ++ K++ I V
Sbjct: 2375 KKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYML 2434
Query: 596 ELQEDLNKESK--EKQDLEKRVLELTSKLEK 510
E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2435 ETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 76.3 bits (186), Expect = 1e-10
Identities = 146/740 (19%), Positives = 274/740 (37%), Gaps = 107/740 (14%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDR----NILEAAKQALEN 2244
+++ L+ K ++ ++ +FE + + +D+ N L+ + +EN
Sbjct: 14619 EKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEIEN 14678
Query: 2243 KVGDFEAAIATLNDELLNEKDDKKCIVND----------------RNIVEADKQALENKV 2112
F IA L ++ K DK+ I N+ ++ +K+ KV
Sbjct: 14679 NTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKADVTSTEKEMYTEKV 14738
Query: 2111 A------DFEATIATLNDELLN--EKDDKKCIVEADKQALESKVS-VFEAAIATLND--E 1965
D + I D L + D K E + Q LE+KV V + T D E
Sbjct: 14739 TYKTELEDSKEKIKPDRDSTLELTDTDSAKTDGEREAQTLETKVQDVLQLTDDTTQDQEE 14798
Query: 1964 LLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD- 1788
L +E ++K I+ + N + Q L+ + E K+ + + LER+++ + + L
Sbjct: 14799 LHDEMENKMKIILELNKAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLSL 14858
Query: 1787 ----KRISDLKADAPQ--------------------------RDQEDDMNALIXXXXXXX 1698
++ +K + Q ++ + +
Sbjct: 14859 TQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQEGQEPIETTGHITKKSEEEI 14918
Query: 1697 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 1518
IV+ LE L E+Q+ +D ++D+ + + + + +S +
Sbjct: 14919 SAKKTKQPIVTKLEDT---LTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQ 14975
Query: 1517 SLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENG------------ 1377
+ E F R E+ + E+S + +++ + E+L D K+ +EN
Sbjct: 14976 TQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLE 15035
Query: 1376 ----------EGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD-KSALTENGEG 1230
E E E L++T ER T D +E E EKV K+ L +N E
Sbjct: 15036 TTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTSNEREKYDEKVTYKTELEDNKE- 15093
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+K+ + L L D+ + D +R E Q LE + D+ T +QE
Sbjct: 15094 ---KKKPDRDSSLKLTDA-----DSAKTDGER---EAQTLETKVQDVLQLTDDTTQDQE- 15141
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 870
ELH E ++K I+ +L+ K + Q L+ K E S +
Sbjct: 15142 ------------------ELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVIME 15183
Query: 869 ELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA 711
L+++ + E E + L +K +++ ++ + + D +
Sbjct: 15184 SLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVATQWETDVQIQQE 15243
Query: 710 EKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK-------- 564
++ + R + EE IS K + K + SEV E+++ LNKE +
Sbjct: 15244 GQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVERMKTM 15303
Query: 563 ---EKQDLEKRVLELTSKLE 513
EK LE+ +L ++E
Sbjct: 15304 MKMEKDQLEQAKSDLQRQME 15323
Score = 72.8 bits (177), Expect = 1e-09
Identities = 142/713 (19%), Positives = 290/713 (40%), Gaps = 73/713 (10%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ + NDRN+L+ + L+ K+ SI D L+ K+A
Sbjct: 7109 EKELLHNDRNLLKKDVEDLQQKL---------------------MSIERDSESLKLDKEA 7147
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE---ATIATL 2082
EN+ + A+ + +L + D+ + I + ++Q +E K A + I TL
Sbjct: 7148 FENE----KEAMKQMKTDLQIQADEIEKIKLE---THHERQRVEEKTAQIQKEREEINTL 7200
Query: 2081 NDELLNEK---DDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
+E+ ++ D+ + +K+A+ES S E A + + N + I RN L
Sbjct: 7201 VEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNAL 7260
Query: 1910 EAAKQALEYKVADLEAAKTTL---NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE 1740
E + + LE K + +ELER D ++A D +S + ++ + E
Sbjct: 7261 EKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQR-QQEAKDHLLSGITDESLLKKSE 7319
Query: 1739 DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKR 1560
+ ++ +S+ + + + + E D K AL KD + +
Sbjct: 7320 AE---IVLQPSQVDKAKPARKTEISDSDKQPVFVQQ--MPEMDLKDALKKDFESEKLDLP 7374
Query: 1559 TVNEIVSHLESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGK 1398
V +++ + + L++ + +E D++ L++ A + K + E +K D
Sbjct: 7375 KVKDVLP--QDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMA 7432
Query: 1397 SALVE------------NGEGCEAEKQG----LEKTVLERRASNLDTMDAIHEEELRKEK 1266
+ L E N + +KQ +EKT ER + +D + ++ K K
Sbjct: 7433 ARLQEERRTNERLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNK 7492
Query: 1265 VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND------ALQRDL-----------D 1137
+ + + E E + K V + SL+ LQ D+ +
Sbjct: 7493 KTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKN 7552
Query: 1136 RVMAEKQALEKRCSD---LEAKNASLTDNQEGHEAEIER-KLEASNLTHN--DELHKEKD 975
+M E L++R SD L+ + L D + A +ER +LE T N ++ K
Sbjct: 7553 TIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKM 7612
Query: 974 DKES-------IMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 816
+KE+ + + D ++ ER++L + + + EL+ + E NE+
Sbjct: 7613 EKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKE 7672
Query: 815 LEAVKQGLEKRVL----------DLEATIHDIEMKTGKDDDYNE--AEKQTLKKRISELE 672
LE +K L+++ + D + ++ + + D +E AE + +++R+ + E
Sbjct: 7673 LEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTE 7732
Query: 671 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ K +K +++ E T+LQ+ + + +++++ ++ EL + E
Sbjct: 7733 K-------KRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKE 7778
Score = 71.2 bits (173), Expect = 4e-09
Identities = 110/577 (19%), Positives = 245/577 (42%), Gaps = 27/577 (4%)
Frame = -2
Query: 2189 EKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALES 2010
EK ++ + +N+ ++L + + + + +L E+++ + I+ + +E
Sbjct: 13281 EKQKEEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRME- 13339
Query: 2009 KVSVFEAAIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1833
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 13340 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 13397
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1659
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 13398 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 13439
Query: 1658 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1479
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 13440 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 13499
Query: 1478 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 1305
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 13500 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 13555
Query: 1304 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 13556 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 13613
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDE--LHKEK 978
+ ++ + +K L+ S+L + L D E++ + E S DE L +E+
Sbjct: 13614 EESMNEMTKKKSELQHERSELYKQKQQLED-MIASESKRDVDTERSRQDKEDEQILKRER 13672
Query: 977 DD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 810
++ K+ ++ + + V+ ++ + + +E S LN++ ++ +N+ L + ++
Sbjct: 13673 EEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQ 13732
Query: 809 AVKQGLEKRVLDLE-------ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILT 651
LEK + DL+ A + + + + D E K+ K +E++ +
Sbjct: 13733 VKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIE 13792
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+L+ + N ++ ++ +L S+E ++L K+
Sbjct: 13793 SVKVRLVTESN----QIDKMNSELKTRSEELENLIKK 13825
Score = 68.6 bits (166), Expect = 3e-08
Identities = 127/670 (18%), Positives = 270/670 (40%), Gaps = 78/670 (11%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
+R LE K AL+++ + E ++ E + + + + +E KQ +EN+ A+
Sbjct: 13082 ERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAE 13141
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
E + + ++ K ++ + + Q E V + T+ DEL +++
Sbjct: 13142 LEIDLENI---IIETKSKQERLESIEVQLQEKNVQM-----GTILDELNKRQEE------ 13187
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
L+A K + + + + DEL I+K+ +++ + + ++D
Sbjct: 13188 ----LDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKD 13243
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE----------LQKEKDDKTAL 1596
Q +M A + +E++ L+L+ E L+K+K++ +
Sbjct: 13244 QFGNMQAELQKGQL-------------EMEMHQLMLNSERDELNGMRVNLEKQKEEFELM 13290
Query: 1595 IKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVLERSASN 1455
++L + P K+ V E+ + L + + E R E+ + +E
Sbjct: 13291 QQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKT 13350
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT-MDAIHE--E 1284
I A EE +KE D + + E CE ++ + + L + + +D D I + +
Sbjct: 13351 KQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEIDIERDEIQKLRK 13406
Query: 1283 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA----------LQRDL-- 1140
+ KEK + + + + E EK E ++ I SL + LQ L
Sbjct: 13407 QYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKLRE 13466
Query: 1139 -----DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEA------------- 1017
D + EK LEK+ +++E DN + E K+EA
Sbjct: 13467 AENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNYLE 13526
Query: 1016 ---SNLTHND---------------ELHKE-KDDKESIMNDLDHVKAERQVLESKVSDME 894
NLT EL+K+ K+ +E M+ ++ +AER+ +E + +M
Sbjct: 13527 QMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERVMDEMA 13586
Query: 893 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY-- 720
+ + E ++ ++ E +R LE + K+ +L+ ++ + + +D
Sbjct: 13587 EEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLEDMIA 13646
Query: 719 NEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+E+++ +R + +E IL + +++ + L E +++ + ++EK+ +EK
Sbjct: 13647 SESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKM 13706
Query: 539 VLELTSKLEK 510
+L + E+
Sbjct: 13707 QSQLNDQKEE 13716
Score = 66.2 bits (160), Expect = 1e-07
Identities = 120/590 (20%), Positives = 242/590 (41%), Gaps = 46/590 (7%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
+R + A+ Q + ++ T+ + DE+ + ++ + + L K ++ E
Sbjct: 8354 ERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKNM-EKTYE 8412
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL----------NDELER 1830
NDE+ EK I + + +L + LE ADLE K + N+ LER
Sbjct: 8413 QQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLER 8469
Query: 1829 KKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1671
+K D II+ +A +R ++ A A +RD E+ M + +
Sbjct: 8470 EKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQEASKNQMV 8528
Query: 1670 --------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH---LESK 1524
+ L+ ++L EL+K K D + DL ++T +EI+ H +SK
Sbjct: 8529 ELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKHEKDTDSK 8582
Query: 1523 SRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENGEGCEAEK 1356
+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 8583 TRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM----------- 8630
Query: 1355 QGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEKQGPEKTV 1194
K V+ +R D M+ I EE+ +E+ + L N + + + +
Sbjct: 8631 ----KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERT 8682
Query: 1193 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEAS 1014
+LE ++ D++R++ E + + +L+ E+ER++E S
Sbjct: 8683 ANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EMERRMEKS 8723
Query: 1013 NLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTLNNELQQK 855
+ DE K + + + D+ ++ L ++ ++E + L + Q++
Sbjct: 8724 KV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQ 8782
Query: 854 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 675
E ER+ LE +K + + D+E +E K++ + Q K+ + +
Sbjct: 8783 ESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSV 8842
Query: 674 EEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 528
E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8843 TE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8888
Score = 65.9 bits (159), Expect = 2e-07
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -2
Query: 1565 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1389
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1388 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1209
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1208 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1029
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1028 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 900
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 899 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 723
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 564
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 563 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 399
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 398 RKTSPLDITKT-----CDAVDISEDST 333
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.9 bits (159), Expect = 2e-07
Identities = 125/657 (19%), Positives = 260/657 (39%), Gaps = 68/657 (10%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
I ++ +E++K L + D E A L + DK+ ++ + ++E +K +
Sbjct: 8418 IQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKI 8477
Query: 2114 VADFEATIATLNDELLNE------KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNE 1953
+ + E+ E E +D ++ + + + ++E + + L ++
Sbjct: 8478 IENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQEASKNQMVELKRQIDKL 8537
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---------------ELERKKDD 1818
+ K ++ + L+ K L+ ++ DLE ++ + E++R+KDD
Sbjct: 8538 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 8597
Query: 1817 NNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-- 1656
I+K L+KR + L+++ ++D + M +I +
Sbjct: 8598 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 8657
Query: 1655 -VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSRSLK--- 1509
+ IL +Q + D +TA ++D +A +R V E+V + R+LK
Sbjct: 8658 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVRNLKGEM 8716
Query: 1508 EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLEKTVL 1332
E + + + E+ E+ I + I++ ++R+ G +E + E + + +
Sbjct: 8717 ERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 8776
Query: 1331 ERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT-VLDLE 1182
E++ + +H+E E+ +EK D E E +++ E T + +
Sbjct: 8777 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 8836
Query: 1181 PTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1011
+ S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +K E
Sbjct: 8837 EELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-KKGEQLL 8895
Query: 1010 LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 831
DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8896 EKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDLFRSELQ 8955
Query: 830 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------------ 687
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8956 RQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKIRFDIAN 9012
Query: 686 ----ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 528
I + + IL D + +D + E +L E D+E+ VLE+
Sbjct: 9013 ARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLVLEV 9065
Score = 64.3 bits (155), Expect = 5e-07
Identities = 123/636 (19%), Positives = 256/636 (40%), Gaps = 49/636 (7%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E AK +++ + E + DE+ E + K I + ++ DK ALE + D
Sbjct: 453 IEQAKVDIQSHMISMEGRV----DEIKRETERLKHIKTE---MQRDKDALEKQKDDTRKA 505
Query: 2093 IATLND---ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLND----ELLNEKDDKKC 1935
E++ E+ + + ++ ++ LE+ A + +ND ++L EK++
Sbjct: 506 KEEAERKRYEIVTEELEHRARLQRERDELEN----IRAEMQRVNDVEKAKILKEKEES-- 559
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAP 1755
+ R ++ E A+++A K LN E + I +RI A
Sbjct: 560 -IRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEI------ERIKHETLRAK 612
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
+ + E+ + I + ++E + EE+QK K+ +L
Sbjct: 613 E-EIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKV----EEIQKTKEQMEEAKVELEEE 667
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEED-------------EVLERSASNLAIMKAI 1434
++VS ++ L+ LR +E+ E+ ++ L ++ +
Sbjct: 668 REDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLEKL 727
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
REE R +K+ + + +E L K L++ ++ + ++ + K +
Sbjct: 728 REETERSQKNIEESKIE---------LMLWKESLDKLKGEMEEDKHVVIMQMNEAKAKEE 778
Query: 1253 ALTENGEGCEAEKQ----GPEKTVLDLEPTIPSLNDALQR------DLDRVMAEKQALEK 1104
LT E E E+ EK +L+ I + + LQR D RV+ K+ E
Sbjct: 779 QLTMVIEQLEIERGEITISREKVKEELDE-INRMRNELQRQHAEMEDWFRVV-NKEKEEA 836
Query: 1103 RCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDELHKEKDDKESIMNDLDHVKAE- 930
+ L A + ++ E+E R ++ L DE+ K+ ++ E I ++ + E
Sbjct: 837 NLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAEELEQINKEIQRARQEL 896
Query: 929 -----------RQVLESKVSDMETTYSTLNNELQQKMDDNEAFL---NERDGLEAVKQGL 792
+++LE + + L+ K D ++ +ER LE ++ +
Sbjct: 897 EKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSERKELEQMRFQV 956
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL---EEAISILTDKAKKLLKDI 621
E DLE +++ + + +K+ L+K S+L E+++ + A++ +
Sbjct: 957 ENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKA 1016
Query: 620 NIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ + E+ E +ED+NK +E + E+ + L +E
Sbjct: 1017 ELLIVEIQEQREDVNKRLEETKQREEALRLLRKDME 1052
Score = 63.5 bits (153), Expect = 8e-07
Identities = 123/686 (17%), Positives = 275/686 (40%), Gaps = 44/686 (6%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++DK V+ N +A ++ L + E I RN L+
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 2258 QALEN--KVGDFEAAIATLNDELLNEKD---DKKCIVNDRNIVEADKQALENK--VADFE 2100
+E+ +V + E A L ++E + K+ +++ E +ALE + +
Sbjct: 820 AEMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKA 879
Query: 2099 ATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA---IATLNDELL-NEKDDKKCI 1932
+ +N E+ + + + + +K++L+ + + + + ELL N+ D KC+
Sbjct: 880 EELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCL 939
Query: 1931 V---NDRNILEAAKQALEYKVADLEAAKTTL-------NDELERKKDDNNAIIKKALDKR 1782
++R LE + +E + DLE + + + +++R+K++ I + +
Sbjct: 940 FEMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDT 999
Query: 1781 ISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
S ++ R + LI + E + +L ++++ E++D
Sbjct: 1000 ESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENERED-- 1057
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE 1422
L K V GK T E+ + ++ + E+ + ER N + IR+ E
Sbjct: 1058 -LEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKME 1116
Query: 1421 LRKEKDGK--SALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR-KEKVDKSA 1251
K + G+ VE + E +E LE +NL+ M A + LR KE ++
Sbjct: 1117 AMKREMGEIEDMKVELTKQKENIDMKMEHARLEM--TNLEMMKA---DLLRQKEDIENQM 1171
Query: 1250 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
L E + E E +L + + + + +++++ K ++K+ +LE +
Sbjct: 1172 LAAKSERQQMEVMRTE--ILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 1070 LTDNQEGHEAEIERKLEASNLTHNDELH---KEKDDKESIMNDLDHVKAERQVLESKVSD 900
T + G ++R++E + + ++K++ E + ++ K + + +
Sbjct: 1230 -TKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQRAKDDMEFKRVETER 1288
Query: 899 METTYSTLNNELQQKMDDNEAFLNERD-----------------GLEAVKQGLEKRVLDL 771
+ + E+Q+ ++ E + ERD +EA ++ + K
Sbjct: 1289 QKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIINLIQQIEATREMVHKTKFQF 1348
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
E + +M T ++ N AE Q L I + E + L + ++ + + E+ L
Sbjct: 1349 ENRMAGSQMGTADQEEMN-AEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLL 1407
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLE 513
+ ++ + +E + E++++ +LE
Sbjct: 1408 KIEVQRRRREIEYREEKIMREQDELE 1433
Score = 61.2 bits (147), Expect = 4e-06
Identities = 115/678 (16%), Positives = 265/678 (39%), Gaps = 38/678 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++ + + + +E K ++ ++ D E + + +R LE +
Sbjct: 616 ENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKR 675
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLN 2079
+ ++ E L +E+L K+ E + + E + + E T +
Sbjct: 676 DLVSREIEQAEF----LRNEILRVKE------------EMESRWRETETEEVELRAKTQH 719
Query: 2078 D----ELLNEKDDKKCIVEADKQALESKVSV--FEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ E L E+ ++ + K ESK+ + ++ ++ L E+ ++DK ++ N
Sbjct: 720 ELERLEKLREETER-----SQKNIEESKIELMLWKESLDKLKGEM---EEDKHVVIMQMN 771
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQED 1737
+A ++ L + LE + + E+ K++ + I ++ ++L+ Q
Sbjct: 772 EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEI-----NRMRNELQR------QHA 820
Query: 1736 DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK-TALIKDLVAAEPGKR 1560
+M V E+ + EE +K + + T ++ +
Sbjct: 821 EMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAE 880
Query: 1559 TVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALV 1386
+ +I ++ + L++ +F +E ++LE + ++ +R E L+ + D L
Sbjct: 881 ELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLF 940
Query: 1385 E-NGEGCEAEKQGL----EKTVLERRASNLDTMDAIHEEELRKEK-----------VDKS 1254
E + E E E+ EK LE+R + D +++++K +D
Sbjct: 941 EMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTE 1000
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMA----------EKQALEK 1104
++ + E +++ E +++++ +N L+ R A E++ LEK
Sbjct: 1001 SMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDLEK 1060
Query: 1103 -RCSDLEAKNASLTDNQEGHE--AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA 933
R L K+ +E + AEIER + + +E K +KE ++ ++ +K
Sbjct: 1061 IRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKR 1120
Query: 932 ERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHD 753
E ++ DM+ + + KM+ E LE +K L ++ D+E +
Sbjct: 1121 EM----GEIEDMKVELTKQKENIDMKMEHARL---EMTNLEMMKADLLRQKEDIENQM-- 1171
Query: 752 IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+ + E + + K+ ++E + + + +K+ + + EL+E + K
Sbjct: 1172 --LAAKSERQQMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 572 ESKEKQDLEKRVLELTSK 519
+E ++E E+ K
Sbjct: 1230 TKREIGEMELMKREMEGK 1247
>gb|KFM76401.1| Myosin heavy chain, non-muscle, partial [Stegodyphus mimosarum]
Length = 1966
Score = 116 bits (291), Expect = 8e-23
Identities = 148/619 (23%), Positives = 277/619 (44%), Gaps = 52/619 (8%)
Frame = -2
Query: 2213 TLNDELLNEKDDKKCIVNDRNIVEADKQALE-----NKVADFEATIAT---LNDELLNEK 2058
T +E L EK+D+ V ++ + + +++A+E KV + + T+A EL E
Sbjct: 844 TKQEEKLIEKEDELRQVKEK-MEKVEQEAVELEKKLQKVVEEKNTLAEQLQAETELCAEA 902
Query: 2057 DDKKCIVEADKQALESKVSVFEAAIAT---LNDELLNEKDDKKCIVNDRNILE------A 1905
++ + + A KQ LE + EA I N L EK KK +N +++ E A
Sbjct: 903 EEMRLRLAARKQELEEILHDLEARIEEEEERNQNLTAEK--KKLQLNIQDLEEQLEEEEA 960
Query: 1904 AKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK--KALDKRISDL-KADAPQRDQEDD 1734
A+Q L+ + +L++ + ++ +D N ++K K L++R+ ++ +A A + ++
Sbjct: 961 ARQKLQLEKVNLDSKIKKIEEDYAVLEDSNQKVVKEKKTLEERLGEVSQALAEEEEKSKH 1020
Query: 1733 MNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTV 1554
++ L + E I+ L E +KE+ + L + E V
Sbjct: 1021 LSKL-----------------KAKQEATIIDLEERHRKEQQARQELERVKRRIETELNDV 1063
Query: 1553 NEIVSHLESKSRSLKEHFLREEED------EVLERSASNLAIMKAIRE-----EELRKEK 1407
E ++ + + L + R+EE+ E +A ++K++RE EL+++
Sbjct: 1064 KEQLNEKKIEVEELHQQLARKEEELNQSLLRCDEEAAGKAQVLKSLREIESQLSELQEDL 1123
Query: 1406 DGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH-EEELRKEKVDKSALTENGEG 1230
D + + E +K+ L + + R LD+ + H +E+LR ++ + A+ + +
Sbjct: 1124 DSER---QTRAKVEKQKRDLNEELEALRNELLDSAENTHAQEDLRTKREQELAMLK--KT 1178
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD---- 1062
+ E Q E + DL + L LD V K +LEK + LEA+ A LT+
Sbjct: 1179 LDEETQSHEAQIADLRQKHNLAIENLNEQLDIVKKAKGSLEKAKAHLEAEKAELTNEVNA 1238
Query: 1061 ------NQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMN---DLDHVKAERQVLESK 909
+ E ++E +L+ +D D+ E + +LD V A+ + L++K
Sbjct: 1239 LSAARQDSERKRKQLELQLQELGAKLSDAEKSRTDNIEKVQKLQAELDSVSAQLEELDTK 1298
Query: 908 VSDMETTYSTLNNELQQKMD------DNEAFLNER-DGLEAVKQGLEKRVLDLEATIHDI 750
+ + L +L + D + LN R LE K+ L++++ + E ++
Sbjct: 1299 ATAATKQAAVLEGQLAEAQDLLQEETRQKLALNSRLRQLENEKENLQEQLDEEEEAKKNL 1358
Query: 749 EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKE 570
E K A+ Q LKKR E + ++ L + KK KDI + ++ ELQ +K
Sbjct: 1359 E----KQVSLLNAQLQELKKRADEDAQQVANLEEVRKKQTKDIEMLQRQIEELQTANDKL 1414
Query: 569 SKEKQDLEKRVLELTSKLE 513
SK K+ L+ V +L +LE
Sbjct: 1415 SKSKKKLQSEVEDLNMELE 1433
Score = 85.9 bits (211), Expect = 2e-13
Identities = 157/714 (21%), Positives = 286/714 (40%), Gaps = 85/714 (11%)
Frame = -2
Query: 2399 LEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQALENKVGDFEAA 2220
L A KQ LE + D E I ++ ++ L+ Q LE ++ + EAA
Sbjct: 909 LAARKQELEEILHDLEARIEEEEERNQ-------NLTAEKKKLQLNIQDLEEQLEEEEAA 961
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
L E +N K I D ++E Q + + E + ++ L E++ K +
Sbjct: 962 RQKLQLEKVNLDSKIKKIEEDYAVLEDSNQKVVKEKKTLEERLGEVSQALAEEEEKSKHL 1021
Query: 2039 VEA---------DKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI-LEAAKQAL 1890
+ D + K + + + E +D K +N++ I +E Q L
Sbjct: 1022 SKLKAKQEATIIDLEERHRKEQQARQELERVKRRIETELNDVKEQLNEKKIEVEELHQQL 1081
Query: 1889 EYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL------------KADAPQRD 1746
K +L + ++E K ++ + ++ ++S+L K + +RD
Sbjct: 1082 ARKEEELNQSLLRCDEEAAGKAQVLKSL--REIESQLSELQEDLDSERQTRAKVEKQKRD 1139
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL-----V 1581
+++ AL + + E + +L + L +E A I DL +
Sbjct: 1140 LNEELEALRNELLDSAENTHAQEDLRTKREQELAMLKKTLDEETQSHEAQIADLRQKHNL 1199
Query: 1580 AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG 1401
A E + +IV + K H E+ + E +A + A R++ RK K
Sbjct: 1200 AIENLNEQL-DIVKKAKGSLEKAKAHLEAEKAELTNEVNA-----LSAARQDSERKRKQL 1253
Query: 1400 KSALVENGEGC-EAEKQ---GLEKTVLERRASNLDTMDAIHEE-ELRKEKVDKSALTENG 1236
+ L E G +AEK +EK +++ + LD++ A EE + + K A G
Sbjct: 1254 ELQLQELGAKLSDAEKSRTDNIEK--VQKLQAELDSVSAQLEELDTKATAATKQAAVLEG 1311
Query: 1235 EGCEAEKQGPEKT--VLDLEPTIPSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
+ EA+ E+T L L + L + LQ LD K+ LEK+ S L A+
Sbjct: 1312 QLAEAQDLLQEETRQKLALNSRLRQLENEKENLQEQLDEEEEAKKNLEKQVSLLNAQLQE 1371
Query: 1070 LT-----DNQEGHEAEIERKLEASNL-----------THNDELHKEKDDKESIMNDLDHV 939
L D Q+ E RK + ++ T ND+L K K +S + DL+ +
Sbjct: 1372 LKKRADEDAQQVANLEEVRKKQTKDIEMLQRQIEELQTANDKLSKSKKKLQSEVEDLN-M 1430
Query: 938 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 759
+ E Q +KVS++E + L ++ +E ERD E + E ++L L
Sbjct: 1431 ELENQ--RTKVSELEKKQRKFDQLLAEEKAVSERIAQERDNAERESREKETKILSLTRAY 1488
Query: 758 HDIEMKTGK----------------------DDDYNEAE--KQTLKKRISELEEAISILT 651
D + K + D + +E E K+ L+ ++++ ++ +L
Sbjct: 1489 EDCQDKMEELERSRKQLQLELEELVSSQGTADKNVHELEKAKRALESQLADQKDQFELLE 1548
Query: 650 DKAK-----KLLKDINIWLSEV---TELQEDLNKESKEKQDLEKRVLELTSKLE 513
D+ + KL ++N+ + +LQ + ++++ L K+V EL S+LE
Sbjct: 1549 DEMQLTEDAKLRLEVNMQAMKAQFERDLQAKDEQAEEKRRALLKQVRELESELE 1602
Score = 81.6 bits (200), Expect = 3e-12
Identities = 132/664 (19%), Positives = 259/664 (39%), Gaps = 36/664 (5%)
Frame = -2
Query: 2411 DRNILEAGKQA--LENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQALENKV 2238
D A KQA LE ++A+ + + + + N++ L+ E
Sbjct: 1296 DTKATAATKQAAVLEGQLAEAQDLLQEETRQKLALNSRLRQLENEKENLQEQLDEEEEAK 1355
Query: 2237 GDFEAAIATLNDELLNEK----DDKKCIVNDRNIVEADKQALENKVADFEATIATLNDEL 2070
+ E ++ LN +L K +D + + N + + + +E E + T ND+L
Sbjct: 1356 KNLEKQVSLLNAQLQELKKRADEDAQQVANLEEVRKKQTKDIEMLQRQIEE-LQTANDKL 1414
Query: 2069 LNEKDDKKCIVEADKQALES---KVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAK 1899
K + VE LE+ KVS E + L EK + I +R+ E
Sbjct: 1415 SKSKKKLQSEVEDLNMELENQRTKVSELEKKQRKFDQLLAEEKAVSERIAQERDNAERES 1474
Query: 1898 QALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALI 1719
+ E K+ L A D++E + +K L + +L + D+
Sbjct: 1475 REKETKILSLTRAYEDCQDKMEELERS-----RKQLQLELEELVSSQGTADKN------- 1522
Query: 1718 XXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 1539
V LE L +L +KD L ++ E K
Sbjct: 1523 ----------------VHELEKAKRALESQLADQKDQFELLEDEMQLTEDAKL------- 1559
Query: 1538 HLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCE 1365
LE +++K F R+ + + + A++K +RE EL E+ ++A + + E
Sbjct: 1560 RLEVNMQAMKAQFERDLQAKDEQAEEKRRALLKQVRELESELEDERKQRTAAISARKKVE 1619
Query: 1364 AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 1185
+ + LE+ L+ + + E+ LR+ K +S L + EA+ E+ L L
Sbjct: 1620 GDLKDLEQ--------QLELANRVKEDALRQLKKLQSQLKDYQRDAEADHAAKEELSLQL 1671
Query: 1184 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLT 1005
+ L ++ D+ +V + E+ EA+ L + EI + +L
Sbjct: 1672 KEVEKKLK-LMEADMIQVQEDLANSERIRRAAEAERDELQE-------EINTTVSRGSLL 1723
Query: 1004 HNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE 825
DE + + + + +L+ ++ ++L K + L N+L + +++ N
Sbjct: 1724 Q-DEKRRLEARIQQLEEELEEEQSNSEILMDKARKAQGQIEQLTNDLASERSNSQKLENN 1782
Query: 824 RDGLEAVKQGLEKRVLDLE--------ATIHDIEMKTGKDD---DYNEAEKQTLKKRISE 678
R LE + L ++ DLE ATI +E K + + D E+Q K +
Sbjct: 1783 RMILERQNKELRAKLQDLETSQRTRTKATIAALEAKVAQVEEQLDMETKERQLQAKANRK 1842
Query: 677 LEEAISIL----------TDKAKKLLKDINIWLS----EVTELQEDLNKESKEKQDLEKR 540
LE+ + + TD+ K+ ++ +N + ++ E +E+ ++E +++ ++
Sbjct: 1843 LEKRLKEVLMQLEDERRHTDQYKEQVEKMNARVKALKRQLDESEEECSREKAQRRKAQRE 1902
Query: 539 VLEL 528
+ +L
Sbjct: 1903 IEDL 1906
>ref|XP_005159743.1| PREDICTED: nesprin-1 isoform X6 [Danio rerio]
Length = 15134
Score = 116 bits (291), Expect = 8e-23
Identities = 145/673 (21%), Positives = 300/673 (44%), Gaps = 29/673 (4%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I +L+ + + K D++ N+R +++ K LE + + E
Sbjct: 5534 IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKI 5593
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + + K I +D++
Sbjct: 5594 KLETQHDR--QRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKD 5651
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-R 1749
+LE K LE ++L K ++LE++K++ A I+K L+K ++ + + +
Sbjct: 5652 MLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQIQKEREDLEKMNENITREMHEIK 5707
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLV 1581
QE+ MN + L+ I L +EL+KEK+ ++ L +
Sbjct: 5708 HQEEQMNQ--------------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQS 5753
Query: 1580 AAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
+ + +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+L+ K
Sbjct: 5754 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKL 5813
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTEN 1239
K + E E K LE+ + R +T + EEL+KE+ D + L E+
Sbjct: 5814 QKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED 5873
Query: 1238 GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+ EK ++ + E ++ L Q++ + K+ + K+ D+E + D
Sbjct: 5874 ---TKREKNSLDEMKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DK 5922
Query: 1058 QEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYST 879
E E+E+ L+A E+HK++ + E + +++ ER + V D+++ +
Sbjct: 5923 IRLREDELEQ-LQA-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIIS 5971
Query: 878 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDD 723
L+ + + D EAF NE++ L+ +K LE+ ++E T H+ EM +
Sbjct: 5972 LDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMET 6031
Query: 722 YNEAEKQTLKKRI------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 561
N KQ K ++ E+E+ + K L +D+ + ++ L+E+ NK +
Sbjct: 6032 MNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQM 6091
Query: 560 KQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPL 381
K LE+ E+ SK+++ R L + A + E L + RK L
Sbjct: 6092 KIGLEREADEI-SKIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVL 6141
Query: 380 DITKTCDAVDISE 342
D K + +++
Sbjct: 6142 DKIKVANESTLAD 6154
Score = 113 bits (283), Expect = 7e-22
Identities = 151/725 (20%), Positives = 298/725 (41%), Gaps = 75/725 (10%)
Frame = -2
Query: 2429 KKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQAL 2250
++ + +++ +E+ + A+ V D + I + ++ N+R +L+ K L
Sbjct: 3974 QREIEKEKSNIESERAAIIKIVEDLQHKIISLDRDAESLKLDREAFENEREVLKQMKTEL 4033
Query: 2249 ENKVGDFEAAIATLNDE-----------LLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
E + + E E + +++K + ++ ++ KQ +E + D
Sbjct: 4034 ERETDEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDM 4093
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATLN 1971
+ + +L+ L K K+ I E + + K+ + + A + +
Sbjct: 4094 DQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKIKEETQNERQRLEKMT 4153
Query: 1970 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII 1803
+EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 4154 EELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSE 4213
Query: 1802 KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQ 1623
K+ R+ + + + Q + + K V +L+ + L +L+
Sbjct: 4214 KEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLE 4273
Query: 1622 KEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL---------- 1473
K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 4274 SLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQIQK 4326
Query: 1472 ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRASN 1314
ER N I + R++ + E K+ A+ + + E EK LEKT L R N
Sbjct: 4327 ERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKEN 4386
Query: 1313 LDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLNDA 1155
L+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 4387 LEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQE 4446
Query: 1154 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKE 981
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+ KE
Sbjct: 4447 LEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKE 4506
Query: 980 KDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGL 813
K D ++S+ DL +K ++QVLE + S +E L E + E NER L
Sbjct: 4507 KHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNL 4566
Query: 812 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISILT 651
E + + L++ DL + + D+ A + TL K + E+ E IS T
Sbjct: 4567 EKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQT 4623
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCICGA 495
+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 4624 EDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLD 4683
Query: 494 RDGLS 480
RD S
Sbjct: 4684 RDAES 4688
Score = 112 bits (280), Expect = 2e-21
Identities = 150/630 (23%), Positives = 279/630 (44%), Gaps = 43/630 (6%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT- 2094
E+ + A+ V D + + +L+ +L + K D++ N+R +++ K L+ K + E
Sbjct: 4248 ESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIK 4307
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ T +D E+ + E DK + + + LN+ K+ K I +DR++
Sbjct: 4308 LETQHDRQRVEEMTAQIQKERDK--INNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDM 4365
Query: 1913 LEAAKQALEYKVADLEAAKTTLND-------ELERKKDDNNAIIKKALDKRISDLKADAP 1755
LE K LE + L AK L E++++++D + +K I D+K
Sbjct: 4366 LEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEK-FTIEIHDIKHQEE 4424
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKD 1587
Q Q+ D + L+ I L +EL+KEK+ D++ L D
Sbjct: 4425 QMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL--D 4462
Query: 1586 LVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELR 1416
L +E K+ VN+I+ ++++ + L K+ EE+ + +E+ + + +E+L+
Sbjct: 4463 LRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLK 4522
Query: 1415 KEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 1236
K K L + E K LE+ +E R + I E EK+ + AL E
Sbjct: 4523 MMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK----EEIQNERQNLEKMTE-ALKEER 4577
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1056
E E + + + +++ S + R+ + ++ + K+ D+E K +N
Sbjct: 4578 EDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK----ENL 4633
Query: 1055 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E E+ R+L+A E+ KEK + ES ER + V D++ L
Sbjct: 4634 RLREDEL-RQLQAEIHKQQREIEKEKINIES----------ERAAIIKDVEDLQHKIICL 4682
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD--------IEMKTGK 732
+ + + D EAF NE++ L+ +K LE+ ++E T HD +++ +
Sbjct: 4683 DRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDR 4742
Query: 731 DDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLN 576
D+ N E+ L ++ ++EE I SI +DK +K D+ SE+ +++EDL
Sbjct: 4743 DEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLE 4802
Query: 575 KE--------SKEKQDLEKRVLELTSKLEK 510
K+ KE++DLEK +T ++ +
Sbjct: 4803 KQKENTLAEIQKEREDLEKMNENITREMHE 4832
Score = 110 bits (275), Expect = 6e-21
Identities = 135/650 (20%), Positives = 282/650 (43%), Gaps = 65/650 (10%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ + + + + + +ND + K+++K + D+ +E KQ +E + D
Sbjct: 5320 EKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHD 5379
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
F+ + +L+ +L K K+ E + + K+ + A + +
Sbjct: 5380 FDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKM 5439
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1806
+EL EK+ + D + IL+ K A E +ADL+ K+ L + E +
Sbjct: 5440 TEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDV 5499
Query: 1805 IKKALDKRISD-----LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1641
K + R+ + L+A+ ++ +E + + I+ N+E +
Sbjct: 5500 ENKKENLRLREDELWQLQAEIYKQQREIEKEKI--------NIESERAAIIKNVED---L 5548
Query: 1640 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE------ 1479
H+ + ++D + +L D A E + + ++ + LE ++ +++ L + D
Sbjct: 5549 QHKIISLDRDSE-SLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEM 5607
Query: 1478 ----VLERSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---- 1338
+R N I + R++ + EK+ ++ + + E EK LEKT
Sbjct: 5608 TAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSEL 5667
Query: 1337 -----VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEP 1179
LE++ N T+ I +E EK++++ E E E+Q +K + L+
Sbjct: 5668 YKVKEDLEKQKEN--TLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 5725
Query: 1178 TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLT 1005
I +L L+++ + +M + L++R S+L+ + ++ D E + E ++ K +
Sbjct: 5726 EIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5785
Query: 1004 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 837
E+ KE+D+ ++S+ DL +K ++QV+E + + +E L E E
Sbjct: 5786 QKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEE 5845
Query: 836 FLNERDGLEAVKQGLEKRVLDLEATIHDI--------EMKTGKDDDYNEAEKQTLKKRIS 681
N+R LE + + L+K D+ D EMK + + +K+ K +
Sbjct: 5846 TQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKE--KSNLE 5903
Query: 680 ELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 531
E++E IS T+ +K I + E+ +LQ +++K+ E ++EK +E
Sbjct: 5904 EMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSE-TEIEKSNIE 5952
Score = 109 bits (272), Expect = 1e-20
Identities = 149/684 (21%), Positives = 293/684 (42%), Gaps = 46/684 (6%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAA 2262
EKDD ++ D + + L E+A+A +S+ ++++
Sbjct: 3517 EKDDLAHLAEDTKRKDDEMKVLH------ESALADIQKEKCNLEQMRESMFKQNEMIDSE 3570
Query: 2261 KQAL---ENKVGDFEAAIATLNDELLNEKDDKKCIV-NDRNIVEADKQALENKVADFEAT 2094
K+ + E+K+ +A I E+ D KK I+ N+R + Q L ++
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEM----DTKKSIIENERAAMTKKNQDLMTELTKQSED 3626
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ E+L EK+ ++E+D++ L+ V + + + + + K D++ + N++ +
Sbjct: 3627 VEIQMKEVLTEKE----LLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEV 3682
Query: 1913 LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---------LDKRISDLKAD 1761
L+ K L+ + ++E K E +R ++ I K + + I D+K
Sbjct: 3683 LKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQ 3742
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 3743 EKQMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL- 3781
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ +E+ + + +E+
Sbjct: 3782 -DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1248
L+ K K E EK LE K LER A + + +EE++ E+ +
Sbjct: 3841 LKMMKLQKQVF-------EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKM 3889
Query: 1247 TENGEGCE------AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
TE + + AE E+ +LD ++ SL LQ++ ++ + K+ D+
Sbjct: 3890 TEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDV 3949
Query: 1088 EAK--NASLTDNQEGH-EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL 918
+ K N L +++ G +AEI ++ E+ KEK + ES ER +
Sbjct: 3950 KNKKENLRLREDELGQLQAEIHKQQR--------EIEKEKSNIES----------ERAAI 3991
Query: 917 ESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDI 750
V D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T H+
Sbjct: 3992 IKIVEDLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHER 4051
Query: 749 EMKTGKDDDYNEA----------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV 600
+ D+ E K+ ++++ E+E+ + K L K++ + +
Sbjct: 4052 QRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQK 4111
Query: 599 TELQEDLNKESKEKQDLEKRVLEL 528
++E+ NK + K +LEK E+
Sbjct: 4112 QVIEEEKNKLEQMKIELEKEADEI 4135
Score = 108 bits (270), Expect = 2e-20
Identities = 151/639 (23%), Positives = 281/639 (43%), Gaps = 55/639 (8%)
Frame = -2
Query: 2261 KQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL 2082
K+ L N + L +L++ + D K + DR E +K+A++ D + +
Sbjct: 5114 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 5173
Query: 2081 NDELLNEKDDKKCIVEADKQALESKVSVFEAAIAT-LNDELLNEKDDK-----KCIVNDR 1920
L + D++ + E Q + + + T D +LNEK+ K I +D+
Sbjct: 5174 EKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDK 5233
Query: 1919 NILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
++LE + LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 5234 DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM-NENITREMHEIKHQ 5292
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q +Q+ D + L+ I L +EL+KEK+ D++
Sbjct: 5293 EEQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQF- 5331
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ + + +++
Sbjct: 5332 -DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKD 5390
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-----EELRKEKVDK 1257
L+ K K E E K LE+ E R +T + EEL+KEK
Sbjct: 5391 LKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESF 5450
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1077
+ L E+ + E+ +LD + N++L DL + EK LE+ ++ +
Sbjct: 5451 THLAEDTK--------KEQEILD---KVKVANESLMADLQK---EKSNLEEMRENISKQT 5496
Query: 1076 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
+ + +E + +L+A E+ KEK + ES ER + V
Sbjct: 5497 EDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIES----------ERAAIIKNVE 5546
Query: 902 DMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEM 744
D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T HD +E
Sbjct: 5547 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 5606
Query: 743 KTG---KD-DDYNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSE 603
T KD D N ++T L ++ ++E+ I SI +DK +K D+ SE
Sbjct: 5607 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSE 5666
Query: 602 VTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 5667 LYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHE 5705
Score = 105 bits (263), Expect = 1e-19
Identities = 126/642 (19%), Positives = 281/642 (43%), Gaps = 46/642 (7%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLND-------ELLNEKDDKKCI-------VN 2160
+I +DR++LE K LE A L E+ E++D + + ++
Sbjct: 4358 AIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIH 4417
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
D E + ++++ + I L EL EK+ I+ D+ L+ + S +
Sbjct: 4418 DIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKE----IIMKDRSQLDLRQSELDKQQT 4473
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII- 1803
+ND + K+++K + D+ E KQ +E + D + ++ +L+++L+ K +
Sbjct: 4474 NVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLED 4533
Query: 1802 -KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
K L++ +L+ +A + + +E+ N + + N +L E
Sbjct: 4534 EKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDE 4593
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFLREEEDEV------ 1476
+ ++++ E + +++ +E+K +L+ E LR+ + E+
Sbjct: 4594 MKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQRE 4653
Query: 1475 LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAEKQGLE--KTVLER 1326
+E+ N+ AI+K + + + + ++D +S ++ E E EK+ L+ KT LER
Sbjct: 4654 IEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENEKEVLKQMKTELER 4712
Query: 1325 RASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQR 1146
A ++ + E + +++V++ A + E E D+ + N ++
Sbjct: 4713 EADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM--VLNEKNRDIEE 4768
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ + ++K LEK DLE + L +E E + E L E+ KE++D
Sbjct: 4769 KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA--------EIQKEREDLE 4820
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
E+I ++ +K + + + K +++ + + N Q+ + E + +R L+ +
Sbjct: 4821 KMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQS 4880
Query: 797 GLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 627
L+K+ + D+ T+ + + KD + E +KQ ++K ++++ L + KK+
Sbjct: 4881 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKL 4940
Query: 626 DINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 510
++ E +L++ +L +E+ E +++ +LEK
Sbjct: 4941 QKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 4982
Score = 104 bits (259), Expect = 4e-19
Identities = 127/622 (20%), Positives = 279/622 (44%), Gaps = 40/622 (6%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I L+ + + K D++ N++ +++ K LE + + E
Sbjct: 4661 IESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKI 4720
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + ++ K I +D++
Sbjct: 4721 KLETQHDR--QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 4778
Query: 1916 ILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+LE K LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 4779 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKM-NENITREMHEIKHQE 4837
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIK 1590
Q +Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 4838 EQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL-- 4875
Query: 1589 DLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+
Sbjct: 4876 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQ 4935
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKT------VLERRASNLDTMDAIHEEELRKE---- 1269
+K K K E E K LE+ + E + ++ + EE +R++
Sbjct: 4936 KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLA 4995
Query: 1268 ------KVDKSALTEN---GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1116
K +K L E E A+ Q + + ++ I L + + + ++ +
Sbjct: 4996 HLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLRED 5055
Query: 1115 ALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNLTHNDELHKEKDDKE----SIMND 951
L+K ++++ + + + + E+E + E N+ EL K+ +D E I+ +
Sbjct: 5056 ELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMM--TELKKKSEDVEIQMKEILTE 5113
Query: 950 LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 771
+ + +R++L V +++ L + ++ D EAF NE++ ++ +K L+ + ++
Sbjct: 5114 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 5173
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE-VTE 594
E I+++T D E ++K ++ I T++ +L + N + E +
Sbjct: 5174 E----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE-ETNRKDMVLNEKNRDIEEKIKS 5228
Query: 593 LQEDLNKESKEKQDLEKRVLEL 528
+Q D + KE+ +LEK EL
Sbjct: 5229 IQSDKDMLEKERHNLEKTRSEL 5250
Score = 100 bits (250), Expect = 5e-18
Identities = 127/675 (18%), Positives = 292/675 (43%), Gaps = 46/675 (6%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ + +++++L K L+N+ + + ++ +++ +
Sbjct: 11357 ERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEE 11416
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N++ + + + + +R + + L+ ++ +F+A ++ +E
Sbjct: 11417 TRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEE 11476
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L ++ + K E K E+K ++ E +E+ EK+ ++ R +E ++
Sbjct: 11477 DLPKEKEMK---EDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKE 11533
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNAL 1722
+E + LE ++ ++ E ++ DD I K+ L+K S++ Q ++E +++
Sbjct: 11534 IEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKK 11593
Query: 1721 IXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK-----------DDKTALIKDLVAA 1575
I +IV L V + E+Q +K D++ LI++ +
Sbjct: 11594 IKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQ 11653
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEEL 1419
+ + E+ ++ + +LKE + +EE + V+E R +L M E+
Sbjct: 11654 QNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQK 11713
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI-----------HEEELRK 1272
+ + + L + E E+ + T L++R +T I +E+L++
Sbjct: 11714 QDLMNQRDLLKQ-----EREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQ 11768
Query: 1271 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1092
+ ++ E E + E + ++ D L+++ E++ L+K+ D
Sbjct: 11769 AIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADD 11828
Query: 1091 LEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAE 930
LE + D +E + + E+KL + +N L D+L KEK+D N+LD ++ E
Sbjct: 11829 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 11888
Query: 929 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEAT 762
Q ++++ +++ T E+ ++ E LN ER LE V+ EK +
Sbjct: 11889 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQ 11944
Query: 761 IHDIEMKTGKD-DDYNEAEKQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
I ++ +KT + D+ ++ + L +K ++ I +L + ++ +++ ++ EL
Sbjct: 11945 IEEMRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEEL 12001
Query: 590 QEDLNKESKEKQDLE 546
+ + K EK+DLE
Sbjct: 12002 KLEKQKIQNEKKDLE 12016
Score = 100 bits (248), Expect = 8e-18
Identities = 135/693 (19%), Positives = 298/693 (43%), Gaps = 107/693 (15%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ +E KQ +E + +
Sbjct: 5737 EKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDN 5796
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
+ + +L+++L K K+ I E + + K+ + A + +
Sbjct: 5797 MDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKM 5856
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------EL 1836
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++
Sbjct: 5857 AEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDI 5916
Query: 1835 ERKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXX 1698
E++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 5917 EKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDA 5976
Query: 1697 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LE 1530
+ N + + + EL++E D+ + K + + ++ V E+ + +
Sbjct: 5977 ESLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMN 6033
Query: 1529 SKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQ 1353
++ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K
Sbjct: 6034 NERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKI 6093
Query: 1352 GLE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEA 1221
GLE K + NL+ M +A+ EE E++++ + E A
Sbjct: 6094 GLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLA 6153
Query: 1220 EKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA 1041
+ Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+
Sbjct: 6154 DLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIES 6213
Query: 1040 EIERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E + E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 6214 ERAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSI 6271
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK----- 732
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6272 ERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKER 6331
Query: 731 -----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 609
D+ Y E EK+ ++ S+LE+A S + K K+I I L
Sbjct: 6332 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIAL 6387
Query: 608 SEVTELQEDLNKESKE------KQDLEKRVLEL 528
+E+ + + L K SKE K + EK+ ++L
Sbjct: 6388 AEIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 6420
Score = 99.4 bits (246), Expect = 1e-17
Identities = 138/664 (20%), Positives = 294/664 (44%), Gaps = 74/664 (11%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R+++E ++ + + + N +L+N++D K +R + L+ ++ +F
Sbjct: 10855 RSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLK---QEREEINHKWTQLQQRIDEF 10911
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+A ++ +E L ++ K + E K E+K+ + E T +++ EK+ ++ V
Sbjct: 10912 DAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVM- 10967
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
R +E K+ L+ + LE ++ ++ E ++ DD I K+ L+K S++ Q
Sbjct: 10968 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11027
Query: 1748 DQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEV-------NILILHEEL----QKEKDDK 1605
++E +++ I +IV L V +I + EEL QK D++
Sbjct: 11028 EEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQ 11087
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE---HFLREEED-------------EVL 1473
++++ + + E+ ++ + +LKE H +E+E+ E L
Sbjct: 11088 GLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDL 11147
Query: 1472 ERSASNLA-----------IMKAIREE------ELRKEKDGKSALVENGEGCEAEKQGLE 1344
E+ ++++ ++K REE +L++ D A V + + KQ
Sbjct: 11148 EKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQ--- 11204
Query: 1343 KTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 1170
K + E R S +T I E + + E K+ K E E A+ + ++ + ++ +
Sbjct: 11205 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLE 11264
Query: 1169 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHN 999
+ + + ++ +K+ +E+ DLE + + ++ E +E+E K+ + +
Sbjct: 11265 RVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKC 11324
Query: 998 D-ELHKE---------KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 849
D E KE ++ K I + + ERQ + + + S L NE ++ +
Sbjct: 11325 DIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKN 11384
Query: 848 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD-----DYNEAEKQTLKKRI 684
NE ER+ L+ ++ LEK ++++ E + K+D + +KQ L+ +
Sbjct: 11385 INEVIKKERETLKEMEAYLEKEKEEMKSITE--ETRRQKEDLEKMSTHINEQKQDLRSQR 11442
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVT-ELQEDLNKESKEKQD------LEKRVLELT 525
LE+ + K K+L + I+ + ++V+ + +EDL KE + K+D + +LE+
Sbjct: 11443 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK 11502
Query: 524 SKLE 513
+K E
Sbjct: 11503 TKAE 11506
Score = 98.2 bits (243), Expect = 3e-17
Identities = 142/710 (20%), Positives = 297/710 (41%), Gaps = 62/710 (8%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ ++ DR+ L+ + L+ + + + T + N+R L+ K+
Sbjct: 4864 EKEIIMKDRSQLDLRQSELDKQQTNMNDIMET--------------MKNERKQLDKDKEE 4909
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE--------- 2100
+E + + E ++ + +D+K + + + E +K LE + E
Sbjct: 4910 MEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKI 4969
Query: 2099 --------ATIATLNDELLNEKDD----------KKCIVEADKQALESKVSVFEAAIATL 1974
+ + +EL+ EK+ +K I++ K A ES ++ + + L
Sbjct: 4970 KEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL 5029
Query: 1973 NDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 1794
+ N K+ I N++ + + L+ +++ ++ ++ E + + A+I++
Sbjct: 5030 EEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREK 5089
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
+++LK + D E M ++ + V NL+ ++ L + ++ K
Sbjct: 5090 -QNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLK 5146
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV---LERSASNLAIM 1443
D+ A + A + K + +E + R EE ER N I
Sbjct: 5147 LDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIE 5206
Query: 1442 KAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---------VLERRASNLDT 1305
+ R++ + EK+ ++ + + E E+ LEKT LE++ N T
Sbjct: 5207 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN--T 5264
Query: 1304 MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEPTIPSLNDALQRDLDRV 1131
+ I +E EK++++ E E E+Q +K + L+ I +L L+++ + +
Sbjct: 5265 LAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 5324
Query: 1130 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----K 969
M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D +
Sbjct: 5325 MKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSR 5384
Query: 968 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 789
+S+ DL +K ++QV E + + +E L E + E NER LE + + L+
Sbjct: 5385 KSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELK 5444
Query: 788 KRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILTDKAK 639
K + E+ H E T K+ + NE A+ Q K + E+ E IS T+ +
Sbjct: 5445 K---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVE 5500
Query: 638 KLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 489
+++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 5501 NKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 5547
Score = 94.7 bits (234), Expect = 3e-16
Identities = 125/616 (20%), Positives = 275/616 (44%), Gaps = 31/616 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGD-------FEAAIATLNDELLNEKDDKKCIVNDRNIVEA 2139
S+ + ++ K+ L+ + D FE I + EL E ++ I + +E
Sbjct: 2366 SLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAEN---IERKKKELEI 2422
Query: 2138 DKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDE-- 1965
K A+ + E + +E D+ + + AD +E + S ++ E
Sbjct: 2423 QKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEES 2482
Query: 1964 -LLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1800
+ EKD K N++N+ L A + L+ + A++E K L + ++R + + I K
Sbjct: 2483 YVKKEKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITK 2542
Query: 1799 KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1620
+ +R+++++ + +++ D+ + ++E + IL+ EL+K
Sbjct: 2543 EK--QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEK 2588
Query: 1619 EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMK 1440
K+ KT L ++ A + K + + + L L ++E E E+ ++ +
Sbjct: 2589 IKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDR 2642
Query: 1439 AIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD 1260
EE + K ++ K + + + E+ L + +R S+ DT++ +L K K +
Sbjct: 2643 RNNEEMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTE 2700
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK 1080
L + + E Q + + +E I + L++ + +K+ LEK E +
Sbjct: 2701 MKDLEK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKE 2753
Query: 1079 NASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSD 900
A ++ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E +
Sbjct: 2754 KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 899 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDD 726
+E + ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D+
Sbjct: 2814 IE----QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDE 2866
Query: 725 DYN--------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDL 579
+ N E+++ TL+K +L++ + + D K+L + I L+E+ + +E L
Sbjct: 2867 EANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREIL 2926
Query: 578 NK----ESKEKQDLEK 543
+ SK+K+DLEK
Sbjct: 2927 EQLKLTLSKQKEDLEK 2942
Score = 94.4 bits (233), Expect = 4e-16
Identities = 139/601 (23%), Positives = 252/601 (41%), Gaps = 10/601 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR-------NIVEADKQAL 2124
+N +E K+ L+N + E + +L E N +D+K + R N + +++ L
Sbjct: 8790 KNQIEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDL 8849
Query: 2123 ENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVF--EAAIATLNDELLNEK 1950
EN + E + +E + ++ I + D + +S+ ++ E I +ELL K
Sbjct: 8850 ENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMK 8909
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL 1770
+ + + +E Q L+ DLE AK E++R++D II + ++ ++
Sbjct: 8910 VE---MGRTKEEIEKESQRLQDATIDLENAKA----EIQRQEDKFEDIIDIKIQEKEREI 8962
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1590
K Q D+E + V +LE+ + + + Q+ +D K L K
Sbjct: 8963 KI---QLDKETKRLS------------EEIELKVKDLEMEMADMKRQKQEIEDTKGLLEK 9007
Query: 1589 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ K+ + + LE + L RE+++ ER+ NL +K + E+LRKE
Sbjct: 9008 E-------KQELKQEKKELEDQMMDLT----REKQETEEERN--NLMALKN-QLEDLRKE 9053
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ EK LEK+ +E + ++++ + K +K +L +
Sbjct: 9054 NE-----------IVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRFE 9102
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
E +KQ E + + + D L R+L + K LEK + N+E
Sbjct: 9103 TEQQKQMLEISTTKMMEEKNEMAD-LSRELQKA---KDELEK---------IAYKTNKER 9149
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 870
HE E +++A ELH + + ++ + Q+++ K + +E ++
Sbjct: 9150 HEVE---QMQA-------ELHSQ----------IQAIEQQGQIMQDKQNHLEEKELSIQR 9189
Query: 869 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKK 690
+ ++ N F E++ L V + KR DLE DIE+ K N + + L+K
Sbjct: 9190 KEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEK 9245
Query: 689 RISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLE 513
SELE D+ IW + L E L + KEK+ LEK +EL SK E
Sbjct: 9246 IRSELENE-----------KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKRE 9294
Query: 512 K 510
+
Sbjct: 9295 Q 9295
Score = 94.4 bits (233), Expect = 4e-16
Identities = 135/648 (20%), Positives = 285/648 (43%), Gaps = 52/648 (8%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVE--------- 2142
I +RN LE K L + E + L+ ++ +K I ++ IVE
Sbjct: 9601 IEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQ 9660
Query: 2141 -------ADKQALENK-VADFEATIATLNDELLNEKDDKKCIVEADK------QALESKV 2004
++ ALE + + D + +A EL N+ + + + EA K + E+ +
Sbjct: 9661 RNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHL 9720
Query: 2003 SVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN---DELE 1833
+ I ++ +E +K+D + I N+ KQ L+ K LE + +N + +
Sbjct: 9721 QRDKKEIKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQ 9777
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1653
++ D+ +A ++K ++ +++ K +R +++N I ++
Sbjct: 9778 QRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHE---INQKIE 9834
Query: 1652 NILILHEELQKEKDDKTAL-IKDLVAAEPGKRTVNEIV---SHLESKSRSLKEHF-LREE 1488
+ L E++ KEK+ A+ IK + E + +E+V + ++ + + L + + E+
Sbjct: 9835 ELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQ 9894
Query: 1487 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1308
E E LE+ S + K E+E R E D K + + EK +EK+ +
Sbjct: 9895 EKEDLEKMKSEIMTQKQEMEKE-RSELDNKI------QQTDLEKHDIEKSKEIVEKLMFE 9947
Query: 1307 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL--------DLEPTIPSLNDAL 1152
+ HE +L+KE++D E +K E+ +L + I ++N+ +
Sbjct: 9948 VEEQRHEIQLQKEELD----------IERQKIADEQDLLIQNKSELQNENERIRNINEVI 9997
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 972
+++ + + + LEK +++ S+T+ + ++E K+ N +L K++D
Sbjct: 9998 KKERETLKEMEAHLEKEKEEMK----SITEETRRQKEDLE-KMSTDIKEQNQDLMKQRDL 10052
Query: 971 KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 792
E D++H E L+ ++ + + + ++ + ++ + + ER LE K
Sbjct: 10053 LEQEKEDINH---EWTQLQQRIDEFD---AQVSKQKEEDLTKQKEMKEERKSLEETK--- 10103
Query: 791 EKRVLDL--EATIHDIEMKTGKDDDYN------EAEKQTLKKRISELEEAISILTDKAKK 636
R++++ +A + DI+ + K+++ E + + L + SEL+ S + + KK
Sbjct: 10104 -ARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKK 10162
Query: 635 LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK-----LEKC 507
L D I E L++ ++ K++Q +E+ EL +K +EKC
Sbjct: 10163 LNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKC 10210
Score = 92.8 bits (229), Expect = 1e-15
Identities = 132/673 (19%), Positives = 297/673 (44%), Gaps = 31/673 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENK-------VGDFEAAIATLNDELLNE----KDDKKCIVNDR-N 2151
++N R++LE ++ + +K + +F+A ++ ++ L + K+D+K + + N
Sbjct: 10324 LMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 10383
Query: 2150 IVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN 1971
++E +A ++ + N+E E+++ + IVE +++ L S E + ++
Sbjct: 10384 VIEMKTKAEPEEIKKEKEKE---NEEEEEEEEEIRVIVETERKELYQIKSELERVRSEID 10440
Query: 1970 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE-----LERKKDDNNAI 1806
E D K I ++ LE K + + +E ++ L+++ LE+ + +
Sbjct: 10441 HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKE 10500
Query: 1805 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1626
I + L + + + D + +E D+ E N+L+ ++
Sbjct: 10501 IVEKLMVEVEEQRKDIQLQKEELDIERQKIAD-----------------EQNLLVQNKAK 10543
Query: 1625 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS---RSLKEHFLREEEDEVLERSASN 1455
+ ++++ + + + E + T+ E+ HL+ + RS+ E R +ED LE+ +++
Sbjct: 10544 LQNENERIKKVDEEIKKE--RETLREMEIHLKKEKEELRSIIEETQRRKED--LEKMSTD 10599
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR 1275
+ K L+ ++D L+E E E+ E T L++R D + E+L
Sbjct: 10600 INEQKL----HLKNQRD----LLEQ----EREEINHEMTQLQQRIDEFDAQVSKQREDLT 10647
Query: 1274 KEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCS 1095
K+++ E E++ E+T + + + +L +M EK+ ++
Sbjct: 10648 KQEM------------EEERKSLEETKARI------IEMKTKAELQEIMQEKEEEDEE-- 10687
Query: 1094 DLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLE 915
E + + +E ++ + E K S + H E K DDK+ I + + ++ + +
Sbjct: 10688 --EMRVIVEMEREELNQIKSELKRVRSEIDH--EQKKLNDDKKIIEQEKEDLEKMKSEIM 10743
Query: 914 SKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 735
++ ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 10744 TQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQ 10803
Query: 734 KDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
K D N+A+ Q +RI E++E I K K+ LK++ L + E + +
Sbjct: 10804 KIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSVIE 10859
Query: 572 ES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFS 399
E+ ++K+DLEK ++ +K + + RD L +E + W + + F
Sbjct: 10860 ETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDEFD 10912
Query: 398 RKTSPL---DITK 369
+ S D+TK
Sbjct: 10913 AQVSKQKEEDLTK 10925
Score = 92.8 bits (229), Expect = 1e-15
Identities = 128/675 (18%), Positives = 276/675 (40%), Gaps = 35/675 (5%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N R++LE ++ + +++ + I + ++ +++D + + + E K E K
Sbjct: 10609 NQRDLLEQEREEINHEMTQLQQRIDEFDAQVSKQRED----LTKQEMEEERKSLEETKAR 10664
Query: 2108 DFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEKDD 1944
E E++ EK+++ + IVE +++ L S + + ++ E DD
Sbjct: 10665 IIEMKTKAELQEIMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDD 10724
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDKRI 1779
KK I ++ LE K + + +E ++ L++ +LER +N+ I + L ++
Sbjct: 10725 KKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKV 10784
Query: 1778 SDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTA 1599
+ + D + +E D+ E QK D++
Sbjct: 10785 EEQRKDIRLQKEELDI---------------------------------ERQKIADEQGL 10811
Query: 1598 LIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
++++ + + E+ ++ + +LKE E L
Sbjct: 10812 VVQNKAKLQNENERIKEMDEEIKKEKETLKE------------------------MEAHL 10847
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---DAIHEE-----------E 1281
RKEK+ +++E E +K+ LEK + N D M D + +E +
Sbjct: 10848 RKEKEEMRSVIE--ETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQ 10905
Query: 1280 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1101
R ++ D + E +K+ E+ E I + + + +++ EK+ E+
Sbjct: 10906 QRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEE- 10964
Query: 1100 CSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV 921
E A + +E + +I+ +LE + E K DDK+ I + + ++ +
Sbjct: 10965 ----EVMRAKVEMKKEELD-QIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSE 11019
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
+ + ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 11020 IMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIE 11079
Query: 740 TGKDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 579
K D N+A+ Q +RI E++E I K K+ LK++ L + E +
Sbjct: 11080 RQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSV 11135
Query: 578 NKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQG 405
+E+ ++K+DLEK ++ +K + + RD L +E + W + +
Sbjct: 11136 IEETQRRQKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDE 11188
Query: 404 FSRKTSPL---DITK 369
F + S D+TK
Sbjct: 11189 FDAQVSKQKEEDLTK 11203
Score = 91.7 bits (226), Expect = 3e-15
Identities = 140/737 (18%), Positives = 310/737 (42%), Gaps = 97/737 (13%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ +V+++ +L + L+NK + D+ +++ +
Sbjct: 9674 ERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEE 9733
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N + K+ K + +R + + ++ +F+A + +E
Sbjct: 9734 TSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEE 9793
Query: 2072 -LLNEK---DDKKCIVEADKQALESK---------VSVFEAAIATLNDELLNEKDDKKCI 1932
L N+K +++KC+ E + + +E K ++ + TL ++++ EK+ + +
Sbjct: 9794 DLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAM 9853
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADA 1758
L+ ++ L+ ++L KT ++ E ++ DD I K+ L+K S++
Sbjct: 9854 TIK---LKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 9910
Query: 1757 PQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD------KTA 1599
+ ++E +++ I +IV L + E+Q +K++ K A
Sbjct: 9911 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIA 9970
Query: 1598 LIKDLVAAEPGK--------RTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIM 1443
+DL+ + R +NE++ + ++ H +E+E+ M
Sbjct: 9971 DEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEKEE------------M 10018
Query: 1442 KAIREEELRKEKDGKSA----------LVENGEGCEAEKQGL--EKTVLERRASNLDTM- 1302
K+I EE R+++D + L++ + E EK+ + E T L++R D
Sbjct: 10019 KSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQV 10078
Query: 1301 ------DAIHEEELRKEKVD----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
D ++E+++E+ K+ + E E E EK + E + +
Sbjct: 10079 SKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 10138
Query: 1151 QRDLDRVMAE-------------------------KQALEKRCSDLEAKNASLTDNQEGH 1047
++LDR+ +E KQ LEK S++ + + + +
Sbjct: 10139 GKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSEL 10198
Query: 1046 EAEIERK-LEASNLTHNDELHKE-----KDDKESIMNDLDHVKAERQVLESKVSDMETTY 885
E +I++ +E ++ ++ E+ ++ ++ K I + + ERQ + + +
Sbjct: 10199 ENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 10258
Query: 884 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------D 723
S L NE ++ + NE ER+ L+ ++ LEK+ ++++ E + K+D D
Sbjct: 10259 SELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSE--ETRRLKEDLEKMSTD 10316
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQD-- 552
N+ K + +R LE+ + K K+L + I+ + ++V++ +E DL KE K+D
Sbjct: 10317 VNKQNKDLMNQR-DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRK 10375
Query: 551 ----LEKRVLELTSKLE 513
+ V+E+ +K E
Sbjct: 10376 SLEETKANVIEMKTKAE 10392
Score = 91.3 bits (225), Expect = 4e-15
Identities = 146/692 (21%), Positives = 284/692 (41%), Gaps = 60/692 (8%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQAL---ENK 2241
+R LE LE K + + I +NILE K L + +
Sbjct: 12977 ERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQ 13036
Query: 2240 VGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNE 2061
V + + T+ + +E ++ +C+ RN +E +K+++ ++++ + I L E+ +E
Sbjct: 13037 VQQQKHEMETIRKTMKSEMENLECL---RNELEDEKKSMLSRLSMEKHEIDKLKTEIQSE 13093
Query: 2060 KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYK 1881
K+ +E +K+ L+ E+ L++ + DK I +++ LE K L+ K
Sbjct: 13094 KES----IEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRK 13149
Query: 1880 VADLE-----AAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIX 1716
L+ A + T + K D++ ++ L +D++ A + E D+ L
Sbjct: 13150 AEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQA--KILESDVQLLQT 13207
Query: 1715 XXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNE 1548
+ +LE N L L +EL+KEK +I D+ + +
Sbjct: 13208 EKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------D 13259
Query: 1547 IVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGE 1374
V+ L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 13260 AVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENM 13318
Query: 1373 GCEAEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTE 1242
+ + ++ + E R D + DA+ + +EL K D E
Sbjct: 13319 KMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKE 13378
Query: 1241 NGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA---- 1083
+ E E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 13379 HVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADD 13438
Query: 1082 --------KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH 942
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 13439 IKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQ 13498
Query: 941 ---------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGL 792
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +
Sbjct: 13499 KEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 13558
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 612
E +EKQ++++ +EL K+L +++ +
Sbjct: 13559 E-------------------------SEKQSIERERAEL-----------KRLKEEVEVQ 13582
Query: 611 LSEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
E T LQ+D N KEK+ LE T ++
Sbjct: 13583 -HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 13613
Score = 90.1 bits (222), Expect = 8e-15
Identities = 141/644 (21%), Positives = 275/644 (42%), Gaps = 49/644 (7%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN- 2118
I NDR E L+N+ D E + + DE N + K+ + +DR+ +E ++ LE
Sbjct: 2638 IDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKT 2697
Query: 2117 --KVADFEATIATLND-------ELLNEKD---DKKCIVEADKQALESKVSVFEAAIATL 1974
++ D E + + + E+ E++ K + K+ LE + FE A +
Sbjct: 2698 KTEMKDLEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1973 N-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERK--KDDNNAI- 1806
+ E L E+ +K+ I D+ + ++ E + L K N+EL+++ +D+ + I
Sbjct: 2758 SLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE 2815
Query: 1805 -IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1638
IK L K D + ++D E+D ++ + + E N+ +L
Sbjct: 2816 QIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVL 2873
Query: 1637 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSA 1461
+ L+ ++D L K+ + + ++ LES++R + ++E E+LE+
Sbjct: 2874 KQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1460 SNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1290
L+ K E+E KEK S E E ++E++G+ KT R MD
Sbjct: 2931 LTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIKKEMD--- 2981
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL 1110
EL++ +++ EN E +KQ ++ + D++ K L
Sbjct: 2982 --ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKIEQIKAEL 3018
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDKESIMNDL 948
+K D E + + ++ +E + ++ +E S DE + K+ + +D
Sbjct: 3019 QKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDR 3078
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
D ++ ER LE ++M L ++++Q ER+ LE +K L K+ DLE
Sbjct: 3079 DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLE 3138
Query: 767 ATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL------TDKAK 639
E + +D ++E++ +K+ + ELE+ L + K
Sbjct: 3139 KERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQK 3198
Query: 638 KLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 510
K+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3199 KIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 89.0 bits (219), Expect = 2e-14
Identities = 139/671 (20%), Positives = 284/671 (42%), Gaps = 55/671 (8%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R I+E ++ L + + + ++ E DDKK I ++ +E K + +
Sbjct: 10690 RVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQM 10749
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALES---KVSVFEAAIATLNDELLNEK----DD 1944
E + L D + + D ++ +E K+ ++ KV I +EL E+ D+
Sbjct: 10750 EEERSEL-DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADE 10808
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISD 1773
+ +V ++ L+ + ++ +++ K TL + L ++K++ ++I++ ++ D
Sbjct: 10809 QGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKED 10868
Query: 1772 LK---ADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
L+ D +++Q+ L+ + L+ I ++ K+K++
Sbjct: 10869 LEKMSTDVNKQNQD-----LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED- 10922
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE---EEDEV-----------LERS 1464
L K E K + +E K+++ E +E EE+EV L++
Sbjct: 10923 -LTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQI 10981
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIH 1290
S L +++ + E +K D K + + E E K + ++ +E S LD + I
Sbjct: 10982 KSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELD--NKIK 11039
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDLEPT--------IPSLNDALQR 1146
+ +L + ++ S E E+Q + K LD+E + LQ
Sbjct: 11040 QTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQN 11099
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ +R+ + ++K L+ A L +E E+ +E + ++L K D
Sbjct: 11100 ENERIKEMDEEIKKEKETLKEMEAHLRKEKE----EMRSVIEETQRRQKEDLEKMSTDVN 11155
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
+ +MN D +K ER+ + K + +LQQ++D+ +A ++++ + KQ
Sbjct: 11156 KQNQDLMNQRDLLKQEREEINHKWT-----------QLQQRIDEFDAQVSKQKEEDLTKQ 11204
Query: 797 G-LEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD 624
+E+ LE T I IEMKT + + + EK+ E EE + + K+ L
Sbjct: 11205 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE------KEEEEVMRAKVEMKKEELDQ 11258
Query: 623 INIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I L SE+ Q+ LN + K EK+DLEK E+ + ++ + + I++
Sbjct: 11259 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 11318
Query: 467 AWMSDCMVPDN 435
++ C + ++
Sbjct: 11319 TYIEKCDIENS 11329
Score = 88.2 bits (217), Expect = 3e-14
Identities = 144/674 (21%), Positives = 290/674 (43%), Gaps = 38/674 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
K + VV + E KQ +E++ E A + I DR E
Sbjct: 2984 KQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMV 3043
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD--------------KQALE 2121
L+N+ D E + + DE N + K+ + +DR+ +E + K+ LE
Sbjct: 3044 IKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLE 3103
Query: 2120 NKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN-DELLNEKDD 1944
+++ E + + E + K + K+ LE + FE A ++ E L E+ +
Sbjct: 3104 SQIRQHEIQLVEIQKER-EILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSE 3162
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKA 1764
++ I N R ++ LE +L AK N+EL++K II+ DK I +KA
Sbjct: 3163 REGIDNTRTRIKQEMDELEKTRQNL--AKEQENNELQKK------IIEDERDK-IEQIKA 3213
Query: 1763 DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+ + ++ + + N N+ +L+K++++ +L ++L
Sbjct: 3214 ELKKEAEKTKLE-------------------LQNERQNLEEAGTKLKKDRENVESLAEEL 3254
Query: 1583 VAAE---PGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRK 1413
+ + E+ ++ ++E L E L+++ +++A K E +L +
Sbjct: 3255 GRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTDIAGAKEDLENQLLE 3309
Query: 1412 EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-EELRKEKVDKSALTENG 1236
E++ V+ E +AEK L L ++ + +D +++ E+LR +V+ L
Sbjct: 3310 EREKNK--VKQAE-IQAEKDML---YLLKQGISEQQVDIVNKTEQLRLREVELEQLQALI 3363
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMA----EKQALEKRCSDLEAKN 1077
+ E + K +++ + + D LQR+++++M ++ LEK S++ A+
Sbjct: 3364 YRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSEMIAQK 3423
Query: 1076 ASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDM 897
+ IE + + N T+ E+ +++ E M +L + K Q ++K+ M
Sbjct: 3424 HQMDIELNKERGLIEERTQMLN-TYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQM 3482
Query: 896 ETTYSTLNNELQQKMDD----NEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
+ ELQ++ DD E NER LE + + LEK DL D + K +
Sbjct: 3483 KI-------ELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLAEDTKRKDDEM 3535
Query: 728 DDYNE---AEKQTLKKRISELEEAI-----SILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+E A+ Q K + ++ E++ I ++K K +L++ ++ ++Q ++N+
Sbjct: 3536 KVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILRE-----DKLQQMQAEINR 3590
Query: 572 ESKEKQDLEKRVLE 531
+ E D +K ++E
Sbjct: 3591 QQTE-MDTKKSIIE 3603
Score = 88.2 bits (217), Expect = 3e-14
Identities = 131/622 (21%), Positives = 266/622 (42%), Gaps = 27/622 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVG-------DFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD 2136
I+ R +E + L+NK+ D E + + ++ ++ +K I + ++ +
Sbjct: 10467 IMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIE 10526
Query: 2135 KQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLN 1956
+Q K+AD + + +L NE + K + E K+ E+ + + L
Sbjct: 10527 RQ----KIADEQNLLVQNKAKLQNENERIKKVDEEIKKERET--------LREMEIHLKK 10574
Query: 1955 EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDK 1785
EK++ + I+ + + K+ LE D+ K L ++ LE+++++ N + + L +
Sbjct: 10575 EKEELRSIIEET---QRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQ-LQQ 10630
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
RI + DA Q +D+ I + + + +E ++E +++
Sbjct: 10631 RIDEF--DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEE 10688
Query: 1604 TALIKDLVAAEPG--KRTVNEIVSHLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAI 1434
+I ++ E K + + S ++ + + L + + E+E E LE+ S + +
Sbjct: 10689 MRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQ 10748
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
EEE R E D K +++T LER +++ I ++ + K + +
Sbjct: 10749 MEEE-RSELDNK----------------IKQTDLERH--DIENSKEIVQKLMVKVEEQRK 10789
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 1074
+ E + E+Q + D + + LQ + +R+ + ++K L+ A
Sbjct: 10790 DIRLQKEELDIERQ----KIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEA 10845
Query: 1073 SLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KESIMNDLDHVKAERQVLESKV 906
L +E E+ +E + ++L K D + +MN D +K ER+ + K
Sbjct: 10846 HLRKEKE----EMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKW 10901
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG-LEKRVLDLEAT-IHDIEMKTGK 732
+ +LQQ++D+ +A ++++ + KQ +E+ LE T I IEMKT
Sbjct: 10902 T-----------QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKT 10950
Query: 731 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKESK 564
+ + + EK+ E EE + + K+ L I L SE+ Q+ LN + K
Sbjct: 10951 EPEKIKKEKE------KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKK 11004
Query: 563 ----EKQDLEKRVLELTSKLEK 510
EK+DLEK E+ + ++
Sbjct: 11005 MIEQEKEDLEKMKSEIMKQRQQ 11026
Score = 87.8 bits (216), Expect = 4e-14
Identities = 143/649 (22%), Positives = 278/649 (42%), Gaps = 45/649 (6%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEA---AIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N+++ ++ E K + + A+ +N EL + + K + + EAD Q +NK
Sbjct: 12958 NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTE 13017
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
+ + + EL EK V+ K +E+ ++ + L + L NE +D+K +
Sbjct: 13018 ELKNILEREKSELYQEKAQ----VQQQKHEMETIRKTMKSEMENL-ECLRNELEDEKKSM 13072
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDKRISDLKADA 1758
R L K ++ ++++ K ++ +E L++ KD+N + + LD I + D
Sbjct: 13073 LSR--LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENES-KRTQLDNTIEKMNMDK 13129
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
+E D +I ++L+ L EE++K + + +D
Sbjct: 13130 LSIQREKD----------------SLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKI 13173
Query: 1577 AEPGKRTVNEIVS---HLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ + E+ S +E +++ L+ L + E E+LE+S + +++ E+L K+
Sbjct: 13174 LDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLR----EDLEKQ 13229
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ ++ EK LE+ + + D + ++ E K+ K+ TE E
Sbjct: 13230 RKRNDLTLQE---LRKEKMALEQMITD-ITKEKDAVASLQNEVSLKQHELKNKETELDE- 13284
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+++ + + LE S N Q+++D + E K +DLE+ L + +
Sbjct: 13285 ---QRKEMDDLRMQLEMRQNSTNKQ-QQEVDVFIVENM---KMRNDLESMKTLLDEERRQ 13337
Query: 1049 HEAEIERKLEASNLTH---------NDELHKEKDDKESIMNDLDHVKAERQ---VLESKV 906
+ I+ + N+ H DEL K D I + +HV+ ER+ VL ++
Sbjct: 13338 LQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD---IKTEKEHVEKEREEIDVLNKEI 13394
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE--MKTGK 732
+ +LN E+ E F E G A + LE+ DL A DI+ ++T K
Sbjct: 13395 IKSKEELQSLNLEI-------EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEK 13447
Query: 731 DDDYNEAEKQT-------LKKRISELEEAIS-------------ILTDKAKKLLKDI-NI 615
+ EK+T L+K+ +ELEE + I+ DK +K ++DI +
Sbjct: 13448 QMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTV 13507
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
SE L+++ ++ +K L ++V +LE+ + RD + K+
Sbjct: 13508 IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKK 13556
Score = 87.4 bits (215), Expect = 5e-14
Identities = 127/646 (19%), Positives = 279/646 (43%), Gaps = 58/646 (8%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
++ KQ ++ K A+ L K+ ++ I ++ +E +K ++ + +
Sbjct: 9310 IQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKV 9369
Query: 2093 IATLNDELLNEKDDKKCIVEAD----KQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
+ E + + +K I EAD K+ E+ E + +++ N ++ K +
Sbjct: 9370 L-----EEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQ 9424
Query: 1925 DRNILEAAKQALEYKVADL-----------EAAKTTLNDELERKKDDNNAIIKKA--LDK 1785
+R ++ KQ L+ + DL E +K +L++E + + N I+++ L+K
Sbjct: 9425 ERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEK 9484
Query: 1784 RISDL-----KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE--- 1629
D+ K D Q + +++ A+ K LE ++ ++EE
Sbjct: 9485 EKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGD 9544
Query: 1628 ---LQKEKDDKTALIKDL-VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE-VLERS 1464
++ + + + I+++ V A+ ++ +++I S LE + + + D ++E+
Sbjct: 9545 LEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKE 9604
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDTMD--- 1299
++L MK+ + ++ +D +S L + + EK +EK ++ER + ++
Sbjct: 9605 RNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDF 9664
Query: 1298 AIHEEELRKEK---VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-------Q 1149
+ +EEL E+ VD+ L CE E Q + + ++E + + + L Q
Sbjct: 9665 KLKKEELALERQNIVDEKYLLAQ---CETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 9721
Query: 1148 RD-------LDRVMAEKQALEKRCSDLEAKNASLT---DNQEGHEAEIERKLEASNLTHN 999
RD ++ +K+ LEK + + + L D E EI K +
Sbjct: 9722 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 9781
Query: 998 DELHKEKDDKESIMNDLDHVKAERQVLES---KVSDMETTYSTLNNELQQKMDDNEAFLN 828
+ + + KE + + ++ ER+ LE K+ +M+T ++E+ QK+++
Sbjct: 9782 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEE------ 9835
Query: 827 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 648
L+ +++ + K EA ++M E++ L + SEL + +
Sbjct: 9836 ----LQTLQEQIMKEKEKAEAMTIKLKM-----------EREDLDQIKSELVREKTEVDH 9880
Query: 647 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
+ KKL DI + E +L++ ++ +KQ++EK EL +K+++
Sbjct: 9881 EQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 9926
Score = 85.5 bits (210), Expect = 2e-13
Identities = 144/713 (20%), Positives = 299/713 (41%), Gaps = 118/713 (16%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
++N R++L+ ++ + +K + I + ++ +K++ + + + E K E K
Sbjct: 10883 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED--LTKQKKMEEERKSLEETK 10940
Query: 2114 VADFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEK 1950
+ E T +++ EK+ + + VE K+ L+ S E + ++ E
Sbjct: 10941 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11000
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDK 1785
DDKK I ++ LE K + + +E ++ L++ +LER +N+ I + L
Sbjct: 11001 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMV 11060
Query: 1784 RISDLKADAPQRDQE---------DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
+ + + D + +E D+ ++ ++ ++ L E
Sbjct: 11061 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKE 11120
Query: 1631 ---ELQKEKDDKTALIK----------------------DLVAAEPGKRTVNEIVSHL-- 1533
L+KEK++ ++I+ DL+ + E ++H
Sbjct: 11121 MEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWT 11180
Query: 1532 --------------ESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGK 1398
+ K L + EEE + LE + + MK E E+++KEK+ +
Sbjct: 11181 QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE 11240
Query: 1397 SALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEE--------LRKEKVD---- 1260
V + E +K+ L+ K+ LER S +D HE++ + +EK D
Sbjct: 11241 EEEVMRAK-VEMKKEELDQIKSQLERVRSEID-----HEQKKLNDDKKMIEQEKEDLEKM 11294
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDL---EPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
KS + + + E E+ E + + I + + +Q+ + V +K ++ + +L
Sbjct: 11295 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 11354
Query: 1088 EAKNASLTDNQE---GHEAEIER------------KLEASNLTHNDE-LHKEKDDKESIM 957
+ + + D Q+ +++E++ K E L + L KEK++ +SI
Sbjct: 11355 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 11414
Query: 956 N-------DLD----HVKAERQVLESKVSDMETTYSTLNN---ELQQKMDDNEAFLNER- 822
DL+ H+ ++Q L S+ +E +N+ +LQQ++D+ +A ++++
Sbjct: 11415 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 11474
Query: 821 -DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDK 645
+ L K+ E R E + +EMKT + + + EK+ E E+ + + +
Sbjct: 11475 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEK-----EEEEQEMRVKVEM 11529
Query: 644 AKKLLKDINIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEK 510
+K ++ I L SE+ Q+ LN + K EK+DLEK E+ + ++
Sbjct: 11530 ERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQ 11582
Score = 85.1 bits (209), Expect = 3e-13
Identities = 128/613 (20%), Positives = 259/613 (42%), Gaps = 34/613 (5%)
Frame = -2
Query: 2261 KQALENKVGD-FEAAIATLNDELLNEKDDKKCIVN-DRNIVEADKQALENKVADFEATIA 2088
KQ + K+ D + + + D + + K ++ +++ +E K ++ ++ +FE +
Sbjct: 14061 KQPIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNME 14120
Query: 2087 -TLND---------ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
TL + +LL++KDD ++ + +E+ F+ IA L + K DK+
Sbjct: 14121 ETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE 14180
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAA------------KTTLNDELERKKDDNNAIIKKA 1794
I N+ L+ +Q E + + + KT L D E+KK D ++ +K
Sbjct: 14181 NIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLK-- 14238
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
++D AD+ + D E + L + V L EEL E
Sbjct: 14239 ----LTD--ADSAKTDGEREAQTL-----------ETKVQDVLQLTDYTTQDQEELHDEM 14281
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAI 1434
++K +I +L A+ + + L+ + RS +E + E LER ++L
Sbjct: 14282 ENKMKIILELNEAK-------KDLQKLKEECRSAEEE--KSVIMESLERRRNSL------ 14326
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLERRASNLDTMDAIHEEELRKEKVDK 1257
E+++ E + +++ + E Q +E K ++ R+ + ++ ++
Sbjct: 14327 --EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQGQEATETT 14384
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPS----LNDALQRDLDRVMAEKQALEKRCSDL 1089
+T+ E + K+ + TV LE T+ S + D+L ++++ V K ++ L
Sbjct: 14385 GHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQL 14444
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD----HVKAERQV 921
E + + E E +E +E + + ++L + DKE + N LD ++ +
Sbjct: 14445 EQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKLLQLTHDKEDLSNTLDKKNKEIENNTET 14503
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
K++ +ETT + + K+ +E +L L+ T + E++
Sbjct: 14504 SLKKIAQLETTIVLMKKD---------------------KENIENELLQLKQTEQEREIQ 14542
Query: 740 TGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 564
G DD NE EK K +ELE+ + KK +D ++ L++ + D +E++
Sbjct: 14543 RGTDDTSNEREKYDEKVTYKTELED-----NKEKKKPDRDSSLKLTDADSAKTDGEREAQ 14597
Query: 563 EKQDLEKRVLELT 525
+ + VL+LT
Sbjct: 14598 TLETKVQDVLQLT 14610
Score = 84.0 bits (206), Expect = 6e-13
Identities = 125/589 (21%), Positives = 252/589 (42%), Gaps = 18/589 (3%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDEL-LNEKDDKKCIVNDRNIVEADKQALENKVADFE- 2100
+E KQ ++N+ + A L +E NE+ +++ + N + A + + DFE
Sbjct: 6551 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQKVN-QQKQATAFQMEKTDFER 6609
Query: 2099 --ATIATLNDELLNEKD-DKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
I N EL ++++ +KK I E K+ TL + N + I
Sbjct: 6610 IKTEIDQANKELADQQEKNKKTITEMQKER------------ETLEEMRANISKQVETIT 6657
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA-LDKRISDLKADAPQ 1752
N+ L + + L D+ L + E + N +++ LD+R SD+ D Q
Sbjct: 6658 NENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQ 6709
Query: 1751 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAE 1572
++ +D M+ ++N+E L + + + K D +L + A E
Sbjct: 6710 KEVDDLMD--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACE 6755
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
+ +NE +E + L ++ ++D++ ++R NL + K + E ++ + K
Sbjct: 6756 QLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKI 6815
Query: 1394 ALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGE 1233
+L G + +EK E+ ++E A+ LD + E + +E++D++
Sbjct: 6816 SLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKT 6875
Query: 1232 GCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE 1053
+ EKT DL+ T +N D + + ++ L K
Sbjct: 6876 YYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK----------------- 6912
Query: 1052 GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 873
E E +++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + +
Sbjct: 6913 --EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMM 6967
Query: 872 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ--- 702
E + D E NE+D L+ ++ ++K + +L+ E + + N+ +Q
Sbjct: 6968 KEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTE 7021
Query: 701 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 561
+K + L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7022 EIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7070
Score = 84.0 bits (206), Expect = 6e-13
Identities = 115/623 (18%), Positives = 262/623 (42%), Gaps = 6/623 (0%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
+ L E+ ++ K ++++ I +++ Q L + + L E+ N K DK +
Sbjct: 8209 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNL 8268
Query: 2039 VEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA 1860
E K LE K E+ L E + KK I ++ +E +++ +E ++ + E
Sbjct: 8269 -EKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVK 8327
Query: 1859 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 1680
T ++++ K++ + ++ L K+ + + D + M L
Sbjct: 8328 GFT---DVQKYKEELQIVTEELLTKKRN---LEQLNSDVQHLMQTLEEVDIQYIKKKAEL 8381
Query: 1679 XKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF 1500
I S ++ IL E+ +K+ ++ +I+++ + ++N + KE+
Sbjct: 8382 EHITSEIQKREQIL-EKQKKKLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENL 8440
Query: 1499 LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRA 1320
RE+++ L R EL++++D VE+ ++ K ++ +
Sbjct: 8441 RREKQETELFRG-------------ELQRQRDE----VESSRQALIMEKDQFKLKIDHQR 8483
Query: 1319 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1140
+ + A +E R E ++ + + E+ + +E + + + L ++
Sbjct: 8484 NEMSA--AFEKEHKRLENMENDLENQRAKLAESLNDAAK-----MEQKLQQMKNELNKEK 8536
Query: 1139 DRVMAEKQALEKRCSDLEAKNASLTDN----QEGHEAEIERKLEASNLTHNDELHKEKDD 972
++V KQ ++ +E + + ++GHE ++++K E + D+L ++ +
Sbjct: 8537 EQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANS 8590
Query: 971 KESIMNDLD-HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG 795
+ + DL ++ +RQ +E ++MET +L+ ++ DD N+RD E
Sbjct: 8591 ESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTH 8650
Query: 794 LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 615
LE + +L D+E K + + +E K+ ++ + LE + K + K++
Sbjct: 8651 LELKREELVRETEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMEN 8710
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPD 438
SE +L ++ +LE RV +E L++ + + E MS+ + +
Sbjct: 8711 VHSERQKLLLLQGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTE 8768
Query: 437 NWVPFEDLVQGFSRKTSPLDITK 369
+ L++ R+ L+I+K
Sbjct: 8769 Q-NEYRKLIEELQREKEQLEISK 8790
Score = 84.0 bits (206), Expect = 6e-13
Identities = 140/656 (21%), Positives = 289/656 (44%), Gaps = 72/656 (10%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
IA + D+LL EK+D + N + + +++++ D + + N +LL K +
Sbjct: 12812 IADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTE---- 12867
Query: 2039 VEADKQALESKVSVFEAAIATLNDELL---NEKDDKKCIVNDRNILEA-AKQALEYKVAD 1872
++ ALE + + +N ++ E++ + ++ + E A+ ++ + D
Sbjct: 12868 IQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 12927
Query: 1871 LEAAKTTL----------NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMN 1728
+E+ K L N EL+ + ++ +IKK ++ + K + QR+++ + MN
Sbjct: 12928 IESVKVRLVTESNQIDKMNSELKTRSEELENLIKK--QQKEFETKENEMQRERKALEKMN 12985
Query: 1727 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG-----K 1563
A + + N + + +LQKEK +KT +K+++ E K
Sbjct: 12986 AELERKSTE----------LKNKIEKVTVWEADLQKEK-NKTEELKNILEREKSELYQEK 13034
Query: 1562 RTVNEIVSHLESKSRSLKEHF-----LREEEDEVLERSASNLAIMK-------------- 1440
V + +E+ +++K LR E ++ + S L++ K
Sbjct: 13035 AQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQSEK 13094
Query: 1439 -AIREE-----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA------ 1296
+I EE +L+ E + K ++N EK ++K ++R +L+ + A
Sbjct: 13095 ESIEEEKKTLKQLKDENESKRTQLDN----TIEKMNMDKLSIQREKDSLEEIKADLQRKA 13150
Query: 1295 -IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1119
+EE+RK S ++++ + + +++ E+ + + I L+ D+ + EK
Sbjct: 13151 EKLDEEMRKAVQITSQISQDAKILDDDRE-KEEELRSMRADIERQAKILESDVQLLQTEK 13209
Query: 1118 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
+ LEK S T+N E ++E++ + ++LT EL KEK E ++ D+
Sbjct: 13210 EILEK----------SKTENDLLRE-DLEKQRKRNDLT-LQELRKEKMALEQMITDITKE 13257
Query: 938 KAERQVLESKVSDMETTYSTLNNEL---QQKMDDNEAFLNER-DGLEAVKQGLEKRVLDL 771
K L+++VS + EL +++MDD L R + +Q ++ +++
Sbjct: 13258 KDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVEN 13317
Query: 770 EATIHDIE-MKTGKDDDYNEAEKQTLKKRISELEEAISIL----------TDKAKKLLKD 624
+D+E MKT D+ E++ L+ I E+ ++L TD+ +K D
Sbjct: 13318 MKMRNDLESMKTLLDE-----ERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 13372
Query: 623 INIWLSEVTELQED---LNKE-SKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I V + +E+ LNKE K K++L+ LE+ ++ I G R + ++++
Sbjct: 13373 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEI-EMFKQEIAGKRAQIESLEQ 13427
Score = 83.6 bits (205), Expect = 8e-13
Identities = 137/630 (21%), Positives = 251/630 (39%), Gaps = 35/630 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN 2118
++V + E KQ +E++ E A L E + + ++ I NDR E L+N
Sbjct: 2792 NVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQN 2851
Query: 2117 KVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ D E + + DE N + KQ LES E L KD +K
Sbjct: 2852 EKKDIETSTDRIRDEEAN--------LRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEK 2903
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+ + E ++ + LE K TL+ + E + + + K+ D IS +
Sbjct: 2904 QLESQNRQHEIQLAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKAD--ISLREELQ 2961
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNIL---ILHEELQKEKDDKTALIKD 1587
Q ++E + +V LE N L I+ +E K + K L K+
Sbjct: 2962 EQSEREGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKE 3021
Query: 1586 LVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSASNLAIMKAIREEELRKE 1410
E +R + E R+ +E ++ + E + +E S IR+EE E
Sbjct: 3022 AEDTEKQRRDI-------EKDRRNNEEMVIKLQNEKKDIETSTDR------IRDEEANLE 3068
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSA------- 1251
K L + + E E+ LEKT E I + E++ ++ K
Sbjct: 3069 VQ-KQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLK 3127
Query: 1250 --LTENGEGCEAEKQGPEKTVLDLEPT-----------IPSLNDALQRDLDRVMAEKQAL 1110
L++ E E E+ EK D+ + I + +++++D + +Q L
Sbjct: 3128 INLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNL 3187
Query: 1109 EKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
K + E + + D ++ E AE++++ E + L EL E+ + E L
Sbjct: 3188 AKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKL----ELQNERQNLEEAGTKL--- 3240
Query: 938 KAERQVLESKVSDMETTYSTLNN-----ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 774
K +R+ +ES ++ L N E+Q+K +++ + ER +E L+K V D
Sbjct: 3241 KKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTD 3295
Query: 773 LEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 603
+ D+E + ++ + N +AE Q K + L++ IS + + + E
Sbjct: 3296 IAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVE 3355
Query: 602 VTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ +LQ + ++ E + K ++ +LE
Sbjct: 3356 LEQLQALIYRQQDEIEANRKAIINEKYRLE 3385
Score = 79.7 bits (195), Expect = 1e-11
Identities = 110/587 (18%), Positives = 242/587 (41%), Gaps = 7/587 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
RN +EA K +EN+ + + D + K ++ + +++ + L KV
Sbjct: 13477 RNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQRE 13536
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + L ++ ++ ++ K I+E++KQ++E + A + L +E + + ++ + D
Sbjct: 13537 QEELERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEE-VEVQHERTLLQQD 13591
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR-- 1749
+N+++ K+ LE + A L +E++RK + + + K+ KR + P+
Sbjct: 13592 KNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIE 13651
Query: 1748 -----DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+EDD+ ++ + +E+ K + + +++
Sbjct: 13652 IEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEET 13711
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
VA + V ++ L S+ + +++H L LA MK I + E + K
Sbjct: 13712 VATTAKQPIVIKLEDTLTSEVQEMRDH---------LNNEIKELARMKTIMKMEKDQLKQ 13762
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE 1224
KS + E E + +E+ + E+ + + H++E +DK + E
Sbjct: 13763 AKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDK-----KNKEIE 13814
Query: 1223 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE 1044
+ K + LE TI + + + ++ KQ ++R +++ K A +T
Sbjct: 13815 NNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQER--EIQRK-ADVTST----- 13866
Query: 1043 AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL 864
E+++ +T+ EL +D KE I D D E +S +D E TL ++
Sbjct: 13867 ---EKEMYTEKVTYKTEL---EDSKEKIKPDRDST-LELTDTDSAKTDGEREAQTLETKV 13919
Query: 863 QQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI 684
Q + + +++ L + K +L+L D+ Q LK+
Sbjct: 13920 QDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDL---------------QKLKEEC 13964
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 543
EE S++ + ++ + SEV L ++++ ++ K ++++
Sbjct: 13965 RSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQ 14011
Score = 77.8 bits (190), Expect = 4e-11
Identities = 127/620 (20%), Positives = 259/620 (41%), Gaps = 70/620 (11%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQA---LESKVSVFEA 1989
D+ + A+ Q L ++ + L E+ K+ I++ D++ L+ +V
Sbjct: 1361 DQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKE----IMKRDREEIRLLKIEVQRRRR 1416
Query: 1988 AIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD-NN 1812
I ++++ E+D+ + + + + ++ LE ++ ++ ND +E+ ++D NN
Sbjct: 1417 EIEYREEKIMREQDELELM---SKMGQRQREELEERLEEVIKE----NDRVEQMREDVNN 1469
Query: 1811 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
A+ K +D+ D++ QE A++ I S + L L
Sbjct: 1470 AL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKS-YRASDLELSA 1526
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 1452
+QKE+ + K+++ E K +N+I +++ +E ++ E+E E +
Sbjct: 1527 SIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKLHEEEK-EMKTKRV 1582
Query: 1451 AIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------EKTVLERR------ 1323
++ R+ + KEK+ G A+ + KQ L EK+ LE +
Sbjct: 1583 SLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIK 1642
Query: 1322 -------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE------- 1203
AS D +I E + +++ ++ + C E+Q E
Sbjct: 1643 QVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDE 1702
Query: 1202 ------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+T D+E + L++ D + K ++K DL+ + A +
Sbjct: 1703 LSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREK 1762
Query: 1058 QEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAERQVLESKVSDMET 891
+E E+E+ + N D E K E D K ++ + ++++A+R+++E + +E
Sbjct: 1763 EEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALEN 1822
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM------KTGKD 729
L E +ER +E + L++ +LE HD++ + KD
Sbjct: 1823 MKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKD 1882
Query: 728 -DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWLSEVTELQEDLNKE 570
++ E + TL K S++ E IS L + K +++ I I ++ ++Q DLN++
Sbjct: 1883 LENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQ 1942
Query: 569 SKEKQDLEKRVLELTSKLEK 510
KE QD++ V S+L+K
Sbjct: 1943 QKEMQDIQNAVFMEKSELKK 1962
Score = 76.6 bits (187), Expect = 1e-10
Identities = 135/691 (19%), Positives = 273/691 (39%), Gaps = 100/691 (14%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R ++E K+ALEN + + + N D+++ + N ++ + + LE K D
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + T + + ++ + + E +++K V E I+ LN + +KD+
Sbjct: 1870 QQ-LQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQ---QKDE------- 1917
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
+E K ++ + DL+ +T LN + + +D NA+ K L K ++ A Q
Sbjct: 1918 ---IENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQL 1971
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAE 1572
Q DM NL+ I+ ++LQ E+D L ++L + +
Sbjct: 1972 KQVGDMMQFTQNEK-------------DNLDRERAAIIEQKLQMERDMTHLLNRELESLK 2018
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
K+ V LE SL E+ ++ LER + + + EE K +
Sbjct: 2019 LVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQ 2078
Query: 1394 ALVENGEGCE----AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK---------- 1257
L E+ E AEKQ LE +E + + M+ E + ++E VDK
Sbjct: 2079 TLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEI 2138
Query: 1256 ------------SALTENGEGC---------------EAEKQGPEKTVLDLEPTIPSLND 1158
+A+ EN + E+Q ++ V ++E +L D
Sbjct: 2139 TFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-D 2197
Query: 1157 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER----KLEASNLTHNDEL 990
+Q ++D+ E+Q +E + +LE + + L ++++ + E+ + E + N EL
Sbjct: 2198 EMQMEVDK---ERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLEL 2254
Query: 989 HKEKDDKESIMNDLD---------------------------------HVKAERQVLESK 909
E KE + +L+ ++A++ K
Sbjct: 2255 QSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKK 2314
Query: 908 VSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
++T L+++ + E+ E + +E K+ + ++ E+ + +EM+
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM 2374
Query: 728 DDYNEA----------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV------T 597
Y E ++Q +K I ++ + I + ++ K++ I V
Sbjct: 2375 KKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYML 2434
Query: 596 ELQEDLNKESK--EKQDLEKRVLELTSKLEK 510
E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2435 ETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 76.3 bits (186), Expect = 1e-10
Identities = 149/734 (20%), Positives = 298/734 (40%), Gaps = 87/734 (11%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDR----NILEAAKQALEN 2244
+++ LE K ++ ++ +FE + +++D+ N L+ + +EN
Sbjct: 14097 EKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIEN 14156
Query: 2243 KVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALE---------NKVADFEATI 2091
F+ IA L + K DK+ I N+ ++ +Q E N+ +++ +
Sbjct: 14157 ITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKV 14216
Query: 2090 ATLNDELLNEKDDKK-------CIVEADK---------QALESKV-SVFEAAIATLND-- 1968
T EL + K+ KK + +AD Q LE+KV V + T D
Sbjct: 14217 -TYKTELEDSKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLTDYTTQDQE 14275
Query: 1967 ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1788
EL +E ++K I+ + N + Q L+ + E K+ + + LER+++ + + L
Sbjct: 14276 ELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLS 14335
Query: 1787 -----KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH-EEL 1626
++ +K + Q + + + + + E ++ I +E
Sbjct: 14336 LTQEIDHLAQIKTEMQQIEIKMQIQT---------------RSVATQWETDVQIQQGQEA 14380
Query: 1625 QKEKDDKTALIKDLVAAEPGKR-TVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLA 1449
+ T ++ ++A+ K+ TV ++ L S+ + +++ +E ED +A
Sbjct: 14381 TETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMED---------VA 14431
Query: 1448 IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE 1269
MK I + E + + KS + E E + +E+ + E+ + + H++E
Sbjct: 14432 RMKTIMKMEKDQLEQAKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSN 14488
Query: 1268 KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
+DK + E + K + LE TI + + + ++ KQ ++R ++
Sbjct: 14489 TLDK-----KNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQER--EI 14541
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA----ERQV 921
+ ++ +E ++ ++ K E L N E K D + D D K E Q
Sbjct: 14542 QRGTDDTSNEREKYDEKVTYKTE---LEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQT 14598
Query: 920 LESKVSDM-----ETT--YSTLNNELQQKM----DDNEA-----FLNER----------- 822
LE+KV D+ +TT L++E++ KM + NEA L E+
Sbjct: 14599 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVI 14658
Query: 821 -DGLEAVKQGLEK---RVLDLEATI-HDIEMKTGKDDDYNEAEKQT------------LK 693
+ LE + LEK VL L I H ++KT + ++QT ++
Sbjct: 14659 MESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVATQWETDVQIQ 14718
Query: 692 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ E E +T K+++ + VT+L++ L E +E +D + +E +++
Sbjct: 14719 QEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVERMK 14778
Query: 512 KCICGARDGLSTIK 471
+ +D L K
Sbjct: 14779 TMMKMEKDQLEQAK 14792
Score = 72.8 bits (177), Expect = 1e-09
Identities = 142/713 (19%), Positives = 290/713 (40%), Gaps = 73/713 (10%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ + NDRN+L+ + L+ K+ SI D L+ K+A
Sbjct: 6246 EKELLHNDRNLLKKDVEDLQQKL---------------------MSIERDSESLKLDKEA 6284
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE---ATIATL 2082
EN+ + A+ + +L + D+ + I + ++Q +E K A + I TL
Sbjct: 6285 FENE----KEAMKQMKTDLQIQADEIEKIKLE---THHERQRVEEKTAQIQKEREEINTL 6337
Query: 2081 NDELLNEK---DDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
+E+ ++ D+ + +K+A+ES S E A + + N + I RN L
Sbjct: 6338 VEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNAL 6397
Query: 1910 EAAKQALEYKVADLEAAKTTL---NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE 1740
E + + LE K + +ELER D ++A D +S + ++ + E
Sbjct: 6398 EKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQR-QQEAKDHLLSGITDESLLKKSE 6456
Query: 1739 DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKR 1560
+ ++ +S+ + + + + E D K AL KD + +
Sbjct: 6457 AE---IVLQPSQVDKAKPARKTEISDSDKQPVFVQQ--MPEMDLKDALKKDFESEKLDLP 6511
Query: 1559 TVNEIVSHLESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGK 1398
V +++ + + L++ + +E D++ L++ A + K + E +K D
Sbjct: 6512 KVKDVLP--QDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMA 6569
Query: 1397 SALVE------------NGEGCEAEKQG----LEKTVLERRASNLDTMDAIHEEELRKEK 1266
+ L E N + +KQ +EKT ER + +D + ++ K K
Sbjct: 6570 ARLQEERRTNERLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNK 6629
Query: 1265 VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND------ALQRDL-----------D 1137
+ + + E E + K V + SL+ LQ D+ +
Sbjct: 6630 KTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKN 6689
Query: 1136 RVMAEKQALEKRCSD---LEAKNASLTDNQEGHEAEIER-KLEASNLTHN--DELHKEKD 975
+M E L++R SD L+ + L D + A +ER +LE T N ++ K
Sbjct: 6690 TIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKM 6749
Query: 974 DKES-------IMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 816
+KE+ + + D ++ ER++L + + + EL+ + E NE+
Sbjct: 6750 EKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKE 6809
Query: 815 LEAVKQGLEKRVL----------DLEATIHDIEMKTGKDDDYNE--AEKQTLKKRISELE 672
LE +K L+++ + D + ++ + + D +E AE + +++R+ + E
Sbjct: 6810 LEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTE 6869
Query: 671 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ K +K +++ E T+LQ+ + + +++++ ++ EL + E
Sbjct: 6870 K-------KRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKE 6915
Score = 71.2 bits (173), Expect = 4e-09
Identities = 110/577 (19%), Positives = 245/577 (42%), Gaps = 27/577 (4%)
Frame = -2
Query: 2189 EKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALES 2010
EK ++ + +N+ ++L + + + + +L E+++ + I+ + +E
Sbjct: 12418 EKQKEEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRME- 12476
Query: 2009 KVSVFEAAIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1833
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 12477 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 12534
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1659
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 12535 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 12576
Query: 1658 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1479
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 12577 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 12636
Query: 1478 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 1305
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 12637 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 12692
Query: 1304 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 12693 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 12750
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDE--LHKEK 978
+ ++ + +K L+ S+L + L D E++ + E S DE L +E+
Sbjct: 12751 EESMNEMTKKKSELQHERSELYKQKQQLED-MIASESKRDVDTERSRQDKEDEQILKRER 12809
Query: 977 DD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 810
++ K+ ++ + + V+ ++ + + +E S LN++ ++ +N+ L + ++
Sbjct: 12810 EEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQ 12869
Query: 809 AVKQGLEKRVLDLE-------ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILT 651
LEK + DL+ A + + + + D E K+ K +E++ +
Sbjct: 12870 VKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIE 12929
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+L+ + N ++ ++ +L S+E ++L K+
Sbjct: 12930 SVKVRLVTESN----QIDKMNSELKTRSEELENLIKK 12962
Score = 68.6 bits (166), Expect = 3e-08
Identities = 127/670 (18%), Positives = 270/670 (40%), Gaps = 78/670 (11%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
+R LE K AL+++ + E ++ E + + + + +E KQ +EN+ A+
Sbjct: 12219 ERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAE 12278
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
E + + ++ K ++ + + Q E V + T+ DEL +++
Sbjct: 12279 LEIDLENI---IIETKSKQERLESIEVQLQEKNVQM-----GTILDELNKRQEE------ 12324
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
L+A K + + + + DEL I+K+ +++ + + ++D
Sbjct: 12325 ----LDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKD 12380
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE----------LQKEKDDKTAL 1596
Q +M A + +E++ L+L+ E L+K+K++ +
Sbjct: 12381 QFGNMQAELQKGQL-------------EMEMHQLMLNSERDELNGMRVNLEKQKEEFELM 12427
Query: 1595 IKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVLERSASN 1455
++L + P K+ V E+ + L + + E R E+ + +E
Sbjct: 12428 QQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKT 12487
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT-MDAIHE--E 1284
I A EE +KE D + + E CE ++ + + L + + +D D I + +
Sbjct: 12488 KQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEIDIERDEIQKLRK 12543
Query: 1283 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA----------LQRDL-- 1140
+ KEK + + + + E EK E ++ I SL + LQ L
Sbjct: 12544 QYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKLRE 12603
Query: 1139 -----DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEA------------- 1017
D + EK LEK+ +++E DN + E K+EA
Sbjct: 12604 AENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNYLE 12663
Query: 1016 ---SNLTHND---------------ELHKE-KDDKESIMNDLDHVKAERQVLESKVSDME 894
NLT EL+K+ K+ +E M+ ++ +AER+ +E + +M
Sbjct: 12664 QMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERVMDEMA 12723
Query: 893 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY-- 720
+ + E ++ ++ E +R LE + K+ +L+ ++ + + +D
Sbjct: 12724 EEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLEDMIA 12783
Query: 719 NEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+E+++ +R + +E IL + +++ + L E +++ + ++EK+ +EK
Sbjct: 12784 SESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKM 12843
Query: 539 VLELTSKLEK 510
+L + E+
Sbjct: 12844 QSQLNDQKEE 12853
Score = 66.2 bits (160), Expect = 1e-07
Identities = 120/590 (20%), Positives = 242/590 (41%), Gaps = 46/590 (7%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
+R + A+ Q + ++ T+ + DE+ + ++ + + L K ++ E
Sbjct: 7491 ERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKNM-EKTYE 7549
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL----------NDELER 1830
NDE+ EK I + + +L + LE ADLE K + N+ LER
Sbjct: 7550 QQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLER 7606
Query: 1829 KKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1671
+K D II+ +A +R ++ A A +RD E+ M + +
Sbjct: 7607 EKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQEASKNQMV 7665
Query: 1670 --------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH---LESK 1524
+ L+ ++L EL+K K D + DL ++T +EI+ H +SK
Sbjct: 7666 ELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKHEKDTDSK 7719
Query: 1523 SRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENGEGCEAEK 1356
+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 7720 TRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM----------- 7767
Query: 1355 QGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEKQGPEKTV 1194
K V+ +R D M+ I EE+ +E+ + L N + + + +
Sbjct: 7768 ----KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERT 7819
Query: 1193 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEAS 1014
+LE ++ D++R++ E + + +L+ E+ER++E S
Sbjct: 7820 ANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EMERRMEKS 7860
Query: 1013 NLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTLNNELQQK 855
+ DE K + + + D+ ++ L ++ ++E + L + Q++
Sbjct: 7861 KV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQ 7919
Query: 854 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 675
E ER+ LE +K + + D+E +E K++ + Q K+ + +
Sbjct: 7920 ESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSV 7979
Query: 674 EEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 528
E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 7980 TE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8025
Score = 65.9 bits (159), Expect = 2e-07
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -2
Query: 1565 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1389
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1388 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1209
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1208 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1029
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1028 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 900
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 899 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 723
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 564
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 563 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 399
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 398 RKTSPLDITKT-----CDAVDISEDST 333
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.9 bits (159), Expect = 2e-07
Identities = 125/657 (19%), Positives = 260/657 (39%), Gaps = 68/657 (10%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
I ++ +E++K L + D E A L + DK+ ++ + ++E +K +
Sbjct: 7555 IQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKI 7614
Query: 2114 VADFEATIATLNDELLNE------KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNE 1953
+ + E+ E E +D ++ + + + ++E + + L ++
Sbjct: 7615 IENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQEASKNQMVELKRQIDKL 7674
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---------------ELERKKDD 1818
+ K ++ + L+ K L+ ++ DLE ++ + E++R+KDD
Sbjct: 7675 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 7734
Query: 1817 NNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-- 1656
I+K L+KR + L+++ ++D + M +I +
Sbjct: 7735 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 7794
Query: 1655 -VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSRSLK--- 1509
+ IL +Q + D +TA ++D +A +R V E+V + R+LK
Sbjct: 7795 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVRNLKGEM 7853
Query: 1508 EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLEKTVL 1332
E + + + E+ E+ I + I++ ++R+ G +E + E + + +
Sbjct: 7854 ERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 7913
Query: 1331 ERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT-VLDLE 1182
E++ + +H+E E+ +EK D E E +++ E T + +
Sbjct: 7914 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 7973
Query: 1181 PTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1011
+ S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +K E
Sbjct: 7974 EELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-KKGEQLL 8032
Query: 1010 LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 831
DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8033 EKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDLFRSELQ 8092
Query: 830 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------------ 687
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8093 RQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKIRFDIAN 8149
Query: 686 ----ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 528
I + + IL D + +D + E +L E D+E+ VLE+
Sbjct: 8150 ARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLVLEV 8202
Score = 64.3 bits (155), Expect = 5e-07
Identities = 123/636 (19%), Positives = 256/636 (40%), Gaps = 49/636 (7%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E AK +++ + E + DE+ E + K I + ++ DK ALE + D
Sbjct: 453 IEQAKVDIQSHMISMEGRV----DEIKRETERLKHIKTE---MQRDKDALEKQKDDTRKA 505
Query: 2093 IATLND---ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLND----ELLNEKDDKKC 1935
E++ E+ + + ++ ++ LE+ A + +ND ++L EK++
Sbjct: 506 KEEAERKRYEIVTEELEHRARLQRERDELEN----IRAEMQRVNDVEKAKILKEKEES-- 559
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAP 1755
+ R ++ E A+++A K LN E + I +RI A
Sbjct: 560 -IRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEI------ERIKHETLRAK 612
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
+ + E+ + I + ++E + EE+QK K+ +L
Sbjct: 613 E-EIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKV----EEIQKTKEQMEEAKVELEEE 667
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEED-------------EVLERSASNLAIMKAI 1434
++VS ++ L+ LR +E+ E+ ++ L ++ +
Sbjct: 668 REDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLEKL 727
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
REE R +K+ + + +E L K L++ ++ + ++ + K +
Sbjct: 728 REETERSQKNIEESKIE---------LMLWKESLDKLKGEMEEDKHVVIMQMNEAKAKEE 778
Query: 1253 ALTENGEGCEAEKQ----GPEKTVLDLEPTIPSLNDALQR------DLDRVMAEKQALEK 1104
LT E E E+ EK +L+ I + + LQR D RV+ K+ E
Sbjct: 779 QLTMVIEQLEIERGEITISREKVKEELDE-INRMRNELQRQHAEMEDWFRVV-NKEKEEA 836
Query: 1103 RCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDELHKEKDDKESIMNDLDHVKAE- 930
+ L A + ++ E+E R ++ L DE+ K+ ++ E I ++ + E
Sbjct: 837 NLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAEELEQINKEIQRARQEL 896
Query: 929 -----------RQVLESKVSDMETTYSTLNNELQQKMDDNEAFL---NERDGLEAVKQGL 792
+++LE + + L+ K D ++ +ER LE ++ +
Sbjct: 897 EKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSERKELEQMRFQV 956
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL---EEAISILTDKAKKLLKDI 621
E DLE +++ + + +K+ L+K S+L E+++ + A++ +
Sbjct: 957 ENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKA 1016
Query: 620 NIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ + E+ E +ED+NK +E + E+ + L +E
Sbjct: 1017 ELLIVEIQEQREDVNKRLEETKQREEALRLLRKDME 1052
Score = 63.5 bits (153), Expect = 8e-07
Identities = 123/686 (17%), Positives = 275/686 (40%), Gaps = 44/686 (6%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++DK V+ N +A ++ L + E I RN L+
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 2258 QALEN--KVGDFEAAIATLNDELLNEKD---DKKCIVNDRNIVEADKQALENK--VADFE 2100
+E+ +V + E A L ++E + K+ +++ E +ALE + +
Sbjct: 820 AEMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKA 879
Query: 2099 ATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA---IATLNDELL-NEKDDKKCI 1932
+ +N E+ + + + + +K++L+ + + + + ELL N+ D KC+
Sbjct: 880 EELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCL 939
Query: 1931 V---NDRNILEAAKQALEYKVADLEAAKTTL-------NDELERKKDDNNAIIKKALDKR 1782
++R LE + +E + DLE + + + +++R+K++ I + +
Sbjct: 940 FEMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDT 999
Query: 1781 ISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
S ++ R + LI + E + +L ++++ E++D
Sbjct: 1000 ESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENERED-- 1057
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE 1422
L K V GK T E+ + ++ + E+ + ER N + IR+ E
Sbjct: 1058 -LEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKME 1116
Query: 1421 LRKEKDGK--SALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR-KEKVDKSA 1251
K + G+ VE + E +E LE +NL+ M A + LR KE ++
Sbjct: 1117 AMKREMGEIEDMKVELTKQKENIDMKMEHARLEM--TNLEMMKA---DLLRQKEDIENQM 1171
Query: 1250 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
L E + E E +L + + + + +++++ K ++K+ +LE +
Sbjct: 1172 LAAKSERQQMEVMRTE--ILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 1070 LTDNQEGHEAEIERKLEASNLTHNDELH---KEKDDKESIMNDLDHVKAERQVLESKVSD 900
T + G ++R++E + + ++K++ E + ++ K + + +
Sbjct: 1230 -TKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQRAKDDMEFKRVETER 1288
Query: 899 METTYSTLNNELQQKMDDNEAFLNERD-----------------GLEAVKQGLEKRVLDL 771
+ + E+Q+ ++ E + ERD +EA ++ + K
Sbjct: 1289 QKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIINLIQQIEATREMVHKTKFQF 1348
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
E + +M T ++ N AE Q L I + E + L + ++ + + E+ L
Sbjct: 1349 ENRMAGSQMGTADQEEMN-AEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLL 1407
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLE 513
+ ++ + +E + E++++ +LE
Sbjct: 1408 KIEVQRRRREIEYREEKIMREQDELE 1433
Score = 61.2 bits (147), Expect = 4e-06
Identities = 115/678 (16%), Positives = 265/678 (39%), Gaps = 38/678 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++ + + + +E K ++ ++ D E + + +R LE +
Sbjct: 616 ENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKR 675
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLN 2079
+ ++ E L +E+L K+ E + + E + + E T +
Sbjct: 676 DLVSREIEQAEF----LRNEILRVKE------------EMESRWRETETEEVELRAKTQH 719
Query: 2078 D----ELLNEKDDKKCIVEADKQALESKVSV--FEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ E L E+ ++ + K ESK+ + ++ ++ L E+ ++DK ++ N
Sbjct: 720 ELERLEKLREETER-----SQKNIEESKIELMLWKESLDKLKGEM---EEDKHVVIMQMN 771
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQED 1737
+A ++ L + LE + + E+ K++ + I ++ ++L+ Q
Sbjct: 772 EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEI-----NRMRNELQR------QHA 820
Query: 1736 DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK-TALIKDLVAAEPGKR 1560
+M V E+ + EE +K + + T ++ +
Sbjct: 821 EMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAE 880
Query: 1559 TVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALV 1386
+ +I ++ + L++ +F +E ++LE + ++ +R E L+ + D L
Sbjct: 881 ELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLF 940
Query: 1385 E-NGEGCEAEKQGL----EKTVLERRASNLDTMDAIHEEELRKEK-----------VDKS 1254
E + E E E+ EK LE+R + D +++++K +D
Sbjct: 941 EMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTE 1000
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMA----------EKQALEK 1104
++ + E +++ E +++++ +N L+ R A E++ LEK
Sbjct: 1001 SMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDLEK 1060
Query: 1103 -RCSDLEAKNASLTDNQEGHE--AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA 933
R L K+ +E + AEIER + + +E K +KE ++ ++ +K
Sbjct: 1061 IRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKR 1120
Query: 932 ERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHD 753
E ++ DM+ + + KM+ E LE +K L ++ D+E +
Sbjct: 1121 EM----GEIEDMKVELTKQKENIDMKMEHARL---EMTNLEMMKADLLRQKEDIENQM-- 1171
Query: 752 IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+ + E + + K+ ++E + + + +K+ + + EL+E + K
Sbjct: 1172 --LAAKSERQQMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 572 ESKEKQDLEKRVLELTSK 519
+E ++E E+ K
Sbjct: 1230 TKREIGEMELMKREMEGK 1247
>ref|XP_685984.6| PREDICTED: nesprin-1 isoform X1 [Danio rerio]
Length = 15997
Score = 116 bits (291), Expect = 8e-23
Identities = 145/673 (21%), Positives = 300/673 (44%), Gaps = 29/673 (4%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I +L+ + + K D++ N+R +++ K LE + + E
Sbjct: 6397 IESERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKI 6456
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + + K I +D++
Sbjct: 6457 KLETQHDR--QRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKD 6514
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-R 1749
+LE K LE ++L K ++LE++K++ A I+K L+K ++ + + +
Sbjct: 6515 MLEKEKHDLEKTRSELYKVK----EDLEKQKENTLAQIQKEREDLEKMNENITREMHEIK 6570
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLV 1581
QE+ MN + L+ I L +EL+KEK+ ++ L +
Sbjct: 6571 HQEEQMNQ--------------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQS 6616
Query: 1580 AAEPGKRTVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
+ + +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+L+ K
Sbjct: 6617 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKL 6676
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTEN 1239
K + E E K LE+ + R +T + EEL+KE+ D + L E+
Sbjct: 6677 QKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED 6736
Query: 1238 GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+ EK ++ + E ++ L Q++ + K+ + K+ D+E + D
Sbjct: 6737 ---TKREKNSLDEMKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DK 6785
Query: 1058 QEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYST 879
E E+E+ L+A E+HK++ + E + +++ ER + V D+++ +
Sbjct: 6786 IRLREDELEQ-LQA-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIIS 6834
Query: 878 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDD 723
L+ + + D EAF NE++ L+ +K LE+ ++E T H+ EM +
Sbjct: 6835 LDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMET 6894
Query: 722 YNEAEKQTLKKRI------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 561
N KQ K ++ E+E+ + K L +D+ + ++ L+E+ NK +
Sbjct: 6895 MNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQM 6954
Query: 560 KQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPL 381
K LE+ E+ SK+++ R L + A + E L + RK L
Sbjct: 6955 KIGLEREADEI-SKIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVL 7004
Query: 380 DITKTCDAVDISE 342
D K + +++
Sbjct: 7005 DKIKVANESTLAD 7017
Score = 112 bits (280), Expect = 2e-21
Identities = 144/655 (21%), Positives = 283/655 (43%), Gaps = 63/655 (9%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ E KQ +E + D
Sbjct: 4636 EKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHD 4695
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
F+ + +L+++L K K+ I E + + K+ + A DE+ K++ + N
Sbjct: 4696 FDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREA-----DEIRKVKEETQ---N 4747
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
+R I E +AL+ + DL N L+ K N + + L +R S+L ++
Sbjct: 4748 ERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRER-SNL------QE 4800
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKDLVA 1578
++++ + + L+ I E +KEK ++ A+IKD+
Sbjct: 4801 MRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVED 4860
Query: 1577 AEPGKRTVNEIVSHLESKSRSLK---EHFLREEED-----EVLERSASNLAIMKAIREEE 1422
+ ++I+S L+ + SLK E F E+E+ LER A + +K + E
Sbjct: 4861 LQ------SKIIS-LDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHE 4913
Query: 1421 LRKEKDGKSALVE--NGEGCEAEKQGLE----KTVLERRASNLDTMDAIHEEELRKEKVD 1260
++ ++ + +E N E + K E K +E+ ++D ++ L+ K+
Sbjct: 4914 RQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQ 4973
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK 1080
K + E EK E+ ++LE D +++ + E+Q LEK +L+ +
Sbjct: 4974 KQVI-------EEEKNKLEQMKIELEKEA----DEIRKIKEETQNERQRLEKMTEELKKE 5022
Query: 1079 NASLTDNQEGHEAE--IERKLEASNLTHNDELHKEKDDKESIM----------------- 957
S T E + E I K++ +N + +L KEK + E +
Sbjct: 5023 KESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKI 5082
Query: 956 ----NDLDHVKA------------------ERQVLESKVSDMETTYSTLNNELQQKMDDN 843
++L+ ++A ER + V D++ +L+ +L+ D
Sbjct: 5083 RLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRDLESLKLDR 5142
Query: 842 EAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAI 663
EAF NER+ L+ +K L+++ ++E I+++T D E ++K ++ I
Sbjct: 5143 EAFENEREVLKQIKTDLKRKAEEIE----KIKLETQHDRQRVEEMTAQIQKERDKINNLI 5198
Query: 662 SILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEK---RVLELTSKLEK 510
T++ +L +I + E + ++ D + KEK DLEK ++L LEK
Sbjct: 5199 E-ETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEK 5252
Score = 112 bits (280), Expect = 2e-21
Identities = 150/630 (23%), Positives = 279/630 (44%), Gaps = 43/630 (6%)
Frame = -2
Query: 2270 EAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT- 2094
E+ + A+ V D + + +L+ +L + K D++ N+R +++ K L+ K + E
Sbjct: 5111 ESERAAIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIK 5170
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ T +D E+ + E DK + + + LN+ K+ K I +DR++
Sbjct: 5171 LETQHDRQRVEEMTAQIQKERDK--INNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDM 5228
Query: 1913 LEAAKQALEYKVADLEAAKTTLND-------ELERKKDDNNAIIKKALDKRISDLKADAP 1755
LE K LE + L AK L E++++++D + +K I D+K
Sbjct: 5229 LEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEK-FTIEIHDIKHQEE 5287
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIKD 1587
Q Q+ D + L+ I L +EL+KEK+ D++ L D
Sbjct: 5288 QMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL--D 5325
Query: 1586 LVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELR 1416
L +E K+ VN+I+ ++++ + L K+ EE+ + +E+ + + +E+L+
Sbjct: 5326 LRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLK 5385
Query: 1415 KEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 1236
K K L + E K LE+ +E R + I E EK+ + AL E
Sbjct: 5386 MMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIK----EEIQNERQNLEKMTE-ALKEER 5440
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 1056
E E + + + +++ S + R+ + ++ + K+ D+E K +N
Sbjct: 5441 EDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKK----ENL 5496
Query: 1055 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E E+ R+L+A E+ KEK + ES ER + V D++ L
Sbjct: 5497 RLREDEL-RQLQAEIHKQQREIEKEKINIES----------ERAAIIKDVEDLQHKIICL 5545
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD--------IEMKTGK 732
+ + + D EAF NE++ L+ +K LE+ ++E T HD +++ +
Sbjct: 5546 DRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIKLETQHDRQRVEEMAAQIQKDR 5605
Query: 731 DDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLN 576
D+ N E+ L ++ ++EE I SI +DK +K D+ SE+ +++EDL
Sbjct: 5606 DEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLE 5665
Query: 575 KE--------SKEKQDLEKRVLELTSKLEK 510
K+ KE++DLEK +T ++ +
Sbjct: 5666 KQKENTLAEIQKEREDLEKMNENITREMHE 5695
Score = 110 bits (276), Expect = 5e-21
Identities = 145/650 (22%), Positives = 280/650 (43%), Gaps = 52/650 (8%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
++ KQ +E + D + + +L+ L K K+ I ++N +E K LE + +
Sbjct: 4942 MQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEIRKI 5001
Query: 2093 ----------IATLNDELLNEKDDKKCIVE---ADKQALESKVSVFEAAIATLNDELLNE 1953
+ + +EL EK+ + E +K+ L+ E+ +A L E N
Sbjct: 5002 KEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNL 5061
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNN----AIIKK- 1797
++ ++ I E K+ + + +LE + ++ E++ +K +N AIIK
Sbjct: 5062 EEMRENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDV 5121
Query: 1796 --------ALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VNIL 1644
+LD+ + LK D + E ++ I K+ + + +
Sbjct: 5122 KDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVE 5181
Query: 1643 ILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK-EHFLREEEDEVLER 1467
+ ++QKE+D LI++ + +NEI + ++ K ++++ + + E+E LE+
Sbjct: 5182 EMTAQIQKERDKINNLIEETNRKD---MVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEK 5238
Query: 1466 SASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 1287
+ S L K E L K++ K A ++ E++ LEK ++ D H+
Sbjct: 5239 TRSKLLRAK----ENLEKQRKIKLAEIQK------EREDLEKM---NEKFTIEIHDIKHQ 5285
Query: 1286 EELRKEKVDKSALTENGEGCEAEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQAL 1110
EE K+K D+ LD L+ I +L L+++ + +M ++ L
Sbjct: 5286 EEQMKQKQDE---------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL 5324
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----KESIMNDL 948
+ R S+L+ + ++ D E + E ++ K + E+ KEK D ++S+ DL
Sbjct: 5325 DLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDL 5384
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
+K ++QVLE + S +E L E + E NER LE + + L++ DL
Sbjct: 5385 KMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL- 5443
Query: 767 ATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISILTDKAKKLLKDINIWLS 606
+ + D+ A + TL K + E+ E IS T+ + +++ +
Sbjct: 5444 --AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLRED 5501
Query: 605 EVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCICGARDGLS 480
E+ +LQ +++K+ KEK ++E + +E K IC RD S
Sbjct: 5502 ELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAES 5551
Score = 110 bits (275), Expect = 6e-21
Identities = 160/704 (22%), Positives = 306/704 (43%), Gaps = 60/704 (8%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAA 2262
EKDD ++ D + + L E+A+A +S+ ++++
Sbjct: 3517 EKDDLAHLAEDTKRKDDEMKVLH------ESALADIQKEKCNLEQMRESMFKQNEMIDSE 3570
Query: 2261 KQAL---ENKVGDFEAAIATLNDELLNEKDDKKCIV-NDRNIVEADKQALENKVADFEAT 2094
K+ + E+K+ +A I E+ D KK I+ N+R + Q L ++
Sbjct: 3571 KKKMILREDKLQQMQAEINRQQTEM----DTKKSIIENERAAMTKKNQDLMTELTKQSED 3626
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ E+L EK+ ++E+D++ L+ V + + + + + K D++ + N++ +
Sbjct: 3627 VEIQMKEVLTEKE----LLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEV 3682
Query: 1913 LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA---------LDKRISDLKAD 1761
L+ K L+ + ++E K E +R ++ I K + + I D+K
Sbjct: 3683 LKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQ 3742
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 3743 EKQMKQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL- 3781
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ +E+ + + +E+
Sbjct: 3782 -DLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSAL 1248
L+ K K E EK LE K LER A + + +EE++ E+ +
Sbjct: 3841 LKMMKLQKQVF-------EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKM 3889
Query: 1247 TENGEGCE------AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
TE + + AE E+ +LD ++ SL LQ++ ++ + K+ D+
Sbjct: 3890 TEELKREKESFTHLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDV 3949
Query: 1088 EAK--NASLTDNQEGH-EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL 918
+ K N L +++ G +AEI ++ E+ KEK + ES ER +
Sbjct: 3950 KNKKENLRLREDELGQLQAEIHKQQR--------EIEKEKSNIES----------ERAAI 3991
Query: 917 ESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDI 750
V D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T HD
Sbjct: 3992 IKIVEDLQHKIISLDRDAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDR 4051
Query: 749 E-------MKTGKDDDYNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDIN 618
+ T + D N ++T L ++ ++EE I SI +DK +K ++
Sbjct: 4052 QRVEEMTAQITKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLE 4111
Query: 617 IWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 4112 KTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITIEMHE 4155
Score = 110 bits (275), Expect = 6e-21
Identities = 135/650 (20%), Positives = 282/650 (43%), Gaps = 65/650 (10%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ + + + + + +ND + K+++K + D+ +E KQ +E + D
Sbjct: 6183 EKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHD 6242
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
F+ + +L+ +L K K+ E + + K+ + A + +
Sbjct: 6243 FDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKM 6302
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 1806
+EL EK+ + D + IL+ K A E +ADL+ K+ L + E +
Sbjct: 6303 TEELKKEKESFTHLAEDTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDV 6362
Query: 1805 IKKALDKRISD-----LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILI 1641
K + R+ + L+A+ ++ +E + + I+ N+E +
Sbjct: 6363 ENKKENLRLREDELWQLQAEIYKQQREIEKEKI--------NIESERAAIIKNVED---L 6411
Query: 1640 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE------ 1479
H+ + ++D + +L D A E + + ++ + LE ++ +++ L + D
Sbjct: 6412 QHKIISLDRDSE-SLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEEM 6470
Query: 1478 ----VLERSASNLAIMKAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---- 1338
+R N I + R++ + EK+ ++ + + E EK LEKT
Sbjct: 6471 TAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSEL 6530
Query: 1337 -----VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEP 1179
LE++ N T+ I +E EK++++ E E E+Q +K + L+
Sbjct: 6531 YKVKEDLEKQKEN--TLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKT 6588
Query: 1178 TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLT 1005
I +L L+++ + +M + L++R S+L+ + ++ D E + E ++ K +
Sbjct: 6589 EIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 6648
Query: 1004 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 837
E+ KE+D+ ++S+ DL +K ++QV+E + + +E L E E
Sbjct: 6649 QKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEE 6708
Query: 836 FLNERDGLEAVKQGLEKRVLDLEATIHDI--------EMKTGKDDDYNEAEKQTLKKRIS 681
N+R LE + + L+K D+ D EMK + + +K+ K +
Sbjct: 6709 TQNKRQILEKMAEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKE--KSNLE 6766
Query: 680 ELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 531
E++E IS T+ +K I + E+ +LQ +++K+ E ++EK +E
Sbjct: 6767 EMKENISKQTEDIEKEKDKIRLREDELEQLQAEIHKQQSE-TEIEKSNIE 6815
Score = 108 bits (270), Expect = 2e-20
Identities = 151/639 (23%), Positives = 281/639 (43%), Gaps = 55/639 (8%)
Frame = -2
Query: 2261 KQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL 2082
K+ L N + L +L++ + D K + DR E +K+A++ D + +
Sbjct: 5977 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 6036
Query: 2081 NDELLNEKDDKKCIVEADKQALESKVSVFEAAIAT-LNDELLNEKDDK-----KCIVNDR 1920
L + D++ + E Q + + + T D +LNEK+ K I +D+
Sbjct: 6037 EKIKLETQHDRQRVEEMAAQIQKERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDK 6096
Query: 1919 NILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 1761
++LE + LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 6097 DMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKEREDVEKM-NENITREMHEIKHQ 6155
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALI 1593
Q +Q+ D + L+ I L +EL+KEK+ D++
Sbjct: 6156 EEQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQF- 6194
Query: 1592 KDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEE 1422
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ + + +++
Sbjct: 6195 -DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLDKD 6253
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-----EELRKEKVDK 1257
L+ K K E E K LE+ E R +T + EEL+KEK
Sbjct: 6254 LKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKESF 6313
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1077
+ L E+ + E+ +LD + N++L DL + EK LE+ ++ +
Sbjct: 6314 THLAEDTK--------KEQEILD---KVKVANESLMADLQK---EKSNLEEMRENISKQT 6359
Query: 1076 ASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS 903
+ + +E + +L+A E+ KEK + ES ER + V
Sbjct: 6360 EDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINIES----------ERAAIIKNVE 6409
Query: 902 DMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEM 744
D++ +L+ + + D EAF NER+ L+ +K LE+ ++E T HD +E
Sbjct: 6410 DLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHDRQRVEE 6469
Query: 743 KTG---KD-DDYNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSE 603
T KD D N ++T L ++ ++E+ I SI +DK +K D+ SE
Sbjct: 6470 MTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDLEKTRSE 6529
Query: 602 VTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 510
+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 6530 LYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHE 6568
Score = 105 bits (263), Expect = 1e-19
Identities = 126/642 (19%), Positives = 281/642 (43%), Gaps = 46/642 (7%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLND-------ELLNEKDDKKCI-------VN 2160
+I +DR++LE K LE A L E+ E++D + + ++
Sbjct: 5221 AIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIH 5280
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
D E + ++++ + I L EL EK+ I+ D+ L+ + S +
Sbjct: 5281 DIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKE----IIMKDRSQLDLRQSELDKQQT 5336
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII- 1803
+ND + K+++K + D+ E KQ +E + D + ++ +L+++L+ K +
Sbjct: 5337 NVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLED 5396
Query: 1802 -KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
K L++ +L+ +A + + +E+ N + + N +L E
Sbjct: 5397 EKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDE 5456
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFLREEEDEV------ 1476
+ ++++ E + +++ +E+K +L+ E LR+ + E+
Sbjct: 5457 MKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQRE 5516
Query: 1475 LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAEKQGLE--KTVLER 1326
+E+ N+ AI+K + + + + ++D +S ++ E E EK+ L+ KT LER
Sbjct: 5517 IEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENEKEVLKQMKTELER 5575
Query: 1325 RASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQR 1146
A ++ + E + +++V++ A + E E D+ + N ++
Sbjct: 5576 EADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM--VLNEKNRDIEE 5631
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ + ++K LEK DLE + L +E E + E L E+ KE++D
Sbjct: 5632 KIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA--------EIQKEREDLE 5683
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
E+I ++ +K + + + K +++ + + N Q+ + E + +R L+ +
Sbjct: 5684 KMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQS 5743
Query: 797 GLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 627
L+K+ + D+ T+ + + KD + E +KQ ++K ++++ L + KK+
Sbjct: 5744 ELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKL 5803
Query: 626 DINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 510
++ E +L++ +L +E+ E +++ +LEK
Sbjct: 5804 QKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 5845
Score = 104 bits (259), Expect = 4e-19
Identities = 127/622 (20%), Positives = 279/622 (44%), Gaps = 40/622 (6%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E+ + A+ V D + I L+ + + K D++ N++ +++ K LE + + E
Sbjct: 5524 IESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKI 5583
Query: 2093 -IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ T +D ++ ++ D+ + + + LN++ + ++ K I +D++
Sbjct: 5584 KLETQHDR--QRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKD 5641
Query: 1916 ILEAAKQALE------YKVA-DLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+LE K LE YKV DLE K E++++++D + + + + + ++K
Sbjct: 5642 MLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKM-NENITREMHEIKHQE 5700
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKD----DKTALIK 1590
Q +Q+ D + L+ I L +EL+KEK+ D++ L
Sbjct: 5701 EQMNQKQDE--------------------LDQLKTEIQNLQQELEKEKEIIMKDRSQL-- 5738
Query: 1589 DLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
DL +E K+ +N+I+ ++++ + L K+ EE+ + +E+ N+ + +E+
Sbjct: 5739 DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQ 5798
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKT------VLERRASNLDTMDAIHEEELRKE---- 1269
+K K K E E K LE+ + E + ++ + EE +R++
Sbjct: 5799 KKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEKMTEELIREKESLA 5858
Query: 1268 ------KVDKSALTEN---GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 1116
K +K L E E A+ Q + + ++ I L + + + ++ +
Sbjct: 5859 HLAEDTKTEKKILDEMKVANESSMADLQREKSILEEMRENISKLKEYIDNEKEKSKLRED 5918
Query: 1115 ALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNLTHNDELHKEKDDKE----SIMND 951
L+K ++++ + + + + E+E + E N+ EL K+ +D E I+ +
Sbjct: 5919 ELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMM--TELKKKSEDVEIQMKEILTE 5976
Query: 950 LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDL 771
+ + +R++L V +++ L + ++ D EAF NE++ ++ +K L+ + ++
Sbjct: 5977 KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFENEKEAMKQMKTDLQIQADEI 6036
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE-VTE 594
E I+++T D E ++K ++ I T++ +L + N + E +
Sbjct: 6037 E----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE-ETNRKDMVLNEKNRDIEEKIKS 6091
Query: 593 LQEDLNKESKEKQDLEKRVLEL 528
+Q D + KE+ +LEK EL
Sbjct: 6092 IQSDKDMLEKERHNLEKTRSEL 6113
Score = 100 bits (250), Expect = 5e-18
Identities = 127/675 (18%), Positives = 292/675 (43%), Gaps = 46/675 (6%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ + +++++L K L+N+ + + ++ +++ +
Sbjct: 12220 ERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSITEE 12279
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N++ + + + + +R + + L+ ++ +F+A ++ +E
Sbjct: 12280 TRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEE 12339
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L ++ + K E K E+K ++ E +E+ EK+ ++ R +E ++
Sbjct: 12340 DLPKEKEMK---EDRKSLEETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKE 12396
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNAL 1722
+E + LE ++ ++ E ++ DD I K+ L+K S++ Q ++E +++
Sbjct: 12397 IEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKK 12456
Query: 1721 IXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK-----------DDKTALIKDLVAA 1575
I +IV L V + E+Q +K D++ LI++ +
Sbjct: 12457 IKQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQ 12516
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEEL 1419
+ + E+ ++ + +LKE + +EE + V+E R +L M E+
Sbjct: 12517 QNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQK 12576
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI-----------HEEELRK 1272
+ + + L + E E+ + T L++R +T I +E+L++
Sbjct: 12577 QDLMNQRDLLKQ-----EREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQ 12631
Query: 1271 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 1092
+ ++ E E + E + ++ D L+++ E++ L+K+ D
Sbjct: 12632 AIKEYESIIEETNRKRTELEEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADD 12691
Query: 1091 LEAKNASLTDNQEGHEAEI--ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAE 930
LE + D +E + + E+KL + +N L D+L KEK+D N+LD ++ E
Sbjct: 12692 LEMQMIEHGDKEEMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKE 12751
Query: 929 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEAT 762
Q ++++ +++ T E+ ++ E LN ER LE V+ EK +
Sbjct: 12752 IQNQKNEMEEIKCELETKRIEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQ 12807
Query: 761 IHDIEMKTGKD-DDYNEAEKQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
I ++ +KT + D+ ++ + L +K ++ I +L + ++ +++ ++ EL
Sbjct: 12808 IEEMRVKTKMERDELDQLMAKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEEL 12864
Query: 590 QEDLNKESKEKQDLE 546
+ + K EK+DLE
Sbjct: 12865 KLEKQKIQNEKKDLE 12879
Score = 100 bits (248), Expect = 8e-18
Identities = 135/693 (19%), Positives = 298/693 (43%), Gaps = 107/693 (15%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
++ I+ A+ L+ + + + +ND + K+++K + D+ +E KQ +E + +
Sbjct: 6600 EKEIIMKARSQLDRRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDN 6659
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA----------------IATL 1974
+ + +L+++L K K+ I E + + K+ + A + +
Sbjct: 6660 MDQSRKSLDEDLKMMKLQKQVIEEEKNKLEQMKIELEREADDIRKIKEETQNKRQILEKM 6719
Query: 1973 NDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------EL 1836
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++
Sbjct: 6720 AEELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDI 6779
Query: 1835 ERKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXX 1698
E++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6780 EKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDA 6839
Query: 1697 XXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LE 1530
+ N + + + EL++E D+ + K + + ++ V E+ + +
Sbjct: 6840 ESLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMN 6896
Query: 1529 SKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQ 1353
++ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K
Sbjct: 6897 NERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKI 6956
Query: 1352 GLE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEA 1221
GLE K + NL+ M +A+ EE E++++ + E A
Sbjct: 6957 GLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLA 7016
Query: 1220 EKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA 1041
+ Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+
Sbjct: 7017 DLQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIES 7076
Query: 1040 EIERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTL 876
E + E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 7077 ERAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSI 7134
Query: 875 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK----- 732
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 7135 ERDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKER 7194
Query: 731 -----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 609
D+ Y E EK+ ++ S+LE+A S + K K+I I L
Sbjct: 7195 EEINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIAL 7250
Query: 608 SEVTELQEDLNKESKE------KQDLEKRVLEL 528
+E+ + + L K SKE K + EK+ ++L
Sbjct: 7251 AEIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 7283
Score = 99.4 bits (246), Expect = 1e-17
Identities = 143/698 (20%), Positives = 299/698 (42%), Gaps = 53/698 (7%)
Frame = -2
Query: 2249 ENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL-NDE 2073
++++ + I L EL EK+ I+ DR+ ++ + L+ + + I T+ N+
Sbjct: 4167 QDELDQLKTEIQNLQQELEKEKE---IIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 4223
Query: 2072 LLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQA 1893
L +KD ++ +E KQ +E + + +I +L+++L K K+ I ++N LE K
Sbjct: 4224 KLLDKDKEE--MEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFE 4281
Query: 1892 LEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMNALI 1719
L+ + ++ K +E + + A+IK+ D + L A+ +R++E D+M
Sbjct: 4282 LQREADEIRKIKEETQNERQSLEKMTKALIKERED--LVHL-AEYTKREKEMLDEMQVA- 4337
Query: 1718 XXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 1539
+I+ + NI E+++ EK+ +L + + +
Sbjct: 4338 --NKSSMADLQREKRILEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEID 4395
Query: 1538 HLESKSRSLKEHFLREEEDEV--LERSASNLAI-MKAIREEELRKEKDGK---------- 1398
++ S + +RE+++ + L++ + ++ I MK I E+ E D
Sbjct: 4396 MEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLK 4455
Query: 1397 ---SALVENGEGCEAEKQ--GLEKTVLERRASNLDTMDAIHEEELRKEKV----DKSALT 1245
++ + E + +++ G EK VL++ ++L I +E+ K K+ D+ +
Sbjct: 4456 QKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQ----IQADEIEKIKLETQHDRQRVE 4511
Query: 1244 ENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR----VMAEKQALEKRCSDLEAKN 1077
E + ++ +++ LN+ + RD++ + ++K LEK +LE
Sbjct: 4512 EKTAQIQKDRDEINNLIVETNRKDMVLNE-MDRDIEEKIKSIQSDKDMLEKERHNLEKTR 4570
Query: 1076 ASLTDNQEGHEA--EIERK----------LEASNLTHNDELHKEKDD-----KESIMNDL 948
+ L +E E EIERK E + H +E K+K D K I N
Sbjct: 4571 SELARAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQ 4630
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
++ E++++ S ++ S L+ + D E NER L+ K+ E++ ++E
Sbjct: 4631 QELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEME 4690
Query: 767 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS-EVTEL 591
HD + D+ + + L+K++ E E K LK + I L E E+
Sbjct: 4691 KEKHDFDQSRKSLDE--DLKMMKLQKQVIEEE----------KSKLKQMKIELEREADEI 4738
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLEKCICGAR------DGLSTIKEAWMSDCMVPDNWV 429
++ + E+Q EK L + E A+ D + E+ ++D + +
Sbjct: 4739 RKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERS-- 4796
Query: 428 PFEDLVQGFSRKTSPLDITKTCDAVDISEDSTTNIQVD 315
+++ + S++T D+ + + + E+ +Q +
Sbjct: 4797 NLQEMRENISKQTE--DVENKKEKIRLREEKLKQLQAE 4832
Score = 99.4 bits (246), Expect = 1e-17
Identities = 138/664 (20%), Positives = 294/664 (44%), Gaps = 74/664 (11%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R+++E ++ + + + N +L+N++D K +R + L+ ++ +F
Sbjct: 11718 RSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLK---QEREEINHKWTQLQQRIDEF 11774
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+A ++ +E L ++ K + E K E+K+ + E T +++ EK+ ++ V
Sbjct: 11775 DAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVM- 11830
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
R +E K+ L+ + LE ++ ++ E ++ DD I K+ L+K S++ Q
Sbjct: 11831 RAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQM 11890
Query: 1748 DQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEV-------NILILHEEL----QKEKDDK 1605
++E +++ I +IV L V +I + EEL QK D++
Sbjct: 11891 EEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQ 11950
Query: 1604 TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE---HFLREEED-------------EVL 1473
++++ + + E+ ++ + +LKE H +E+E+ E L
Sbjct: 11951 GLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDL 12010
Query: 1472 ERSASNLA-----------IMKAIREE------ELRKEKDGKSALVENGEGCEAEKQGLE 1344
E+ ++++ ++K REE +L++ D A V + + KQ
Sbjct: 12011 EKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQ--- 12067
Query: 1343 KTVLERRASNLDTMDAIHEEELRKE--KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 1170
K + E R S +T I E + + E K+ K E E A+ + ++ + ++ +
Sbjct: 12068 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLE 12127
Query: 1169 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHN 999
+ + + ++ +K+ +E+ DLE + + ++ E +E+E K+ + +
Sbjct: 12128 RVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQTYIEKC 12187
Query: 998 D-ELHKE---------KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 849
D E KE ++ K I + + ERQ + + + S L NE ++ +
Sbjct: 12188 DIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKN 12247
Query: 848 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD-----DYNEAEKQTLKKRI 684
NE ER+ L+ ++ LEK ++++ E + K+D + +KQ L+ +
Sbjct: 12248 INEVIKKERETLKEMEAYLEKEKEEMKSITE--ETRRQKEDLEKMSTHINEQKQDLRSQR 12305
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVT-ELQEDLNKESKEKQD------LEKRVLELT 525
LE+ + K K+L + I+ + ++V+ + +EDL KE + K+D + +LE+
Sbjct: 12306 DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMK 12365
Query: 524 SKLE 513
+K E
Sbjct: 12366 TKAE 12369
Score = 98.2 bits (243), Expect = 3e-17
Identities = 142/710 (20%), Positives = 297/710 (41%), Gaps = 62/710 (8%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ ++ DR+ L+ + L+ + + + T + N+R L+ K+
Sbjct: 5727 EKEIIMKDRSQLDLRQSELDKQQTNMNDIMET--------------MKNERKQLDKDKEE 5772
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE--------- 2100
+E + + E ++ + +D+K + + + E +K LE + E
Sbjct: 5773 MEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKI 5832
Query: 2099 --------ATIATLNDELLNEKDD----------KKCIVEADKQALESKVSVFEAAIATL 1974
+ + +EL+ EK+ +K I++ K A ES ++ + + L
Sbjct: 5833 KEETQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSIL 5892
Query: 1973 NDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 1794
+ N K+ I N++ + + L+ +++ ++ ++ E + + A+I++
Sbjct: 5893 EEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREK 5952
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
+++LK + D E M ++ + V NL+ ++ L + ++ K
Sbjct: 5953 -QNMMTELKKKS--EDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLK 6009
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEV---LERSASNLAIM 1443
D+ A + A + K + +E + R EE ER N I
Sbjct: 6010 LDREAFENEKEAMKQMKTDLQIQADEIEKIKLETQHDRQRVEEMAAQIQKERDKINNLIE 6069
Query: 1442 KAIREEELRKEKDGK-----SALVENGEGCEAEKQGLEKT---------VLERRASNLDT 1305
+ R++ + EK+ ++ + + E E+ LEKT LE++ N T
Sbjct: 6070 ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKEN--T 6127
Query: 1304 MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK--TVLDLEPTIPSLNDALQRDLDRV 1131
+ I +E EK++++ E E E+Q +K + L+ I +L L+++ + +
Sbjct: 6128 LAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEII 6187
Query: 1130 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDD----K 969
M ++ + R S+L+ + ++ D E + E ++ K + E+ KEK D +
Sbjct: 6188 MKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSR 6247
Query: 968 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 789
+S+ DL +K ++QV E + + +E L E + E NER LE + + L+
Sbjct: 6248 KSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELK 6307
Query: 788 KRVLDLEATIHDIEMKTGKDDDY-------NE---AEKQTLKKRISELEEAISILTDKAK 639
K + E+ H E T K+ + NE A+ Q K + E+ E IS T+ +
Sbjct: 6308 K---EKESFTHLAE-DTKKEQEILDKVKVANESLMADLQKEKSNLEEMRENISKQTEDVE 6363
Query: 638 KLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARD 489
+++ + E+ +LQ ++ K+ +E +EK + + S+ I D
Sbjct: 6364 NKKENLRLREDELWQLQAEIYKQQRE---IEKEKINIESERAAIIKNVED 6410
Score = 94.7 bits (234), Expect = 3e-16
Identities = 125/616 (20%), Positives = 275/616 (44%), Gaps = 31/616 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGD-------FEAAIATLNDELLNEKDDKKCIVNDRNIVEA 2139
S+ + ++ K+ L+ + D FE I + EL E ++ I + +E
Sbjct: 2366 SLEMENEAMKKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAEN---IERKKKELEI 2422
Query: 2138 DKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDE-- 1965
K A+ + E + +E D+ + + AD +E + S ++ E
Sbjct: 2423 QKPAVYTETYMLETQKPVVEKSKTDELDEVRKKINADLSEVEKQKSALVQMNLKISQEES 2482
Query: 1964 -LLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK 1800
+ EKD K N++N+ L A + L+ + A++E K L + ++R + + I K
Sbjct: 2483 YVKKEKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITK 2542
Query: 1799 KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQK 1620
+ +R+++++ + +++ D+ + ++E + IL+ EL+K
Sbjct: 2543 EK--QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEK 2588
Query: 1619 EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMK 1440
K+ KT L ++ A + K + + + L L ++E E E+ ++ +
Sbjct: 2589 IKEKKTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDR 2642
Query: 1439 AIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVD 1260
EE + K ++ K + + + E+ L + +R S+ DT++ +L K K +
Sbjct: 2643 RNNEEMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTE 2700
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK 1080
L + + E Q + + +E I + L++ + +K+ LEK E +
Sbjct: 2701 MKDLEK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKE 2753
Query: 1079 NASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSD 900
A ++ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E +
Sbjct: 2754 KADISLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDK 2813
Query: 899 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDD 726
+E + ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D+
Sbjct: 2814 IE----QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDE 2866
Query: 725 DYN--------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDL 579
+ N E+++ TL+K +L++ + + D K+L + I L+E+ + +E L
Sbjct: 2867 EANLRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREIL 2926
Query: 578 NK----ESKEKQDLEK 543
+ SK+K+DLEK
Sbjct: 2927 EQLKLTLSKQKEDLEK 2942
Score = 94.4 bits (233), Expect = 4e-16
Identities = 147/772 (19%), Positives = 322/772 (41%), Gaps = 64/772 (8%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
K D++ + N++ +L+ K L+ + + E I DR L+
Sbjct: 3670 KQDRELLENEKEVLKQMKTDLQGEAEEIEKIKLETQHERQRVEEMTAQIQKDREYLQKMN 3729
Query: 2258 QALENKVGDF---EAAIATLNDELLNEKDD----KKCIVNDRNIVEADKQALENKVADFE 2100
+ ++ D E + DEL K + ++ + ++ I+ D+ L+ K ++ +
Sbjct: 3730 DNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLKQSELD 3789
Query: 2099 ATIATLNDELLNEKDDKKCI------VEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ND + K+++K + +E K+ +E + F+ +L+++L K K+
Sbjct: 3790 KQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQ 3849
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
++N LE K LE + ++ K + +E +++L+K +LK
Sbjct: 3850 VFEEEKNKLEQMKIELEREAGEIRKIKEEIQNE------------RQSLEKMTEELK--- 3894
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
R++E + +I+ ++V L ELQKEK + + +++
Sbjct: 3895 --REKESFTHLA--------EDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK 3944
Query: 1577 AEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERS------ASNLAIMKAIREEELR 1416
+ E + E + L+ +++ + E+S A+ + I++ ++ + +
Sbjct: 3945 QTEDVKNKKENLRLREDELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIIS 4004
Query: 1415 KEKDGKSALVENGEGCEAEKQGLE--KTVLERRASNL----------------------- 1311
++D +S ++ E E E++ L+ KT LER +
Sbjct: 4005 LDRDAESLKLDR-EAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITK 4063
Query: 1310 --DTMDAIHEEELRKEKV--DKS--------ALTENGEGCEAEKQGPEKTVLDLEPTIPS 1167
D ++ + EE RK+ V +K+ ++ + + E EK EKT +L
Sbjct: 4064 ERDKINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELY----K 4119
Query: 1166 LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELH 987
+ + L++ + +AE ++K DLE N ++T +E + H +E
Sbjct: 4120 VKEDLEKQKENTLAE---IQKEREDLEKMNENIT-------------IEMHEIKHQEEQM 4163
Query: 986 KEKDD-----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER 822
K+K D K I N ++ E++++ S+++ S L+ + D E NER
Sbjct: 4164 KQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNER 4223
Query: 821 DGLEAVKQGLEKRVLDLEATIHDIEMK-TGKDDDYN--EAEKQTLKKRISELEEAISILT 651
L+ K+ +E++ ++E +++ D+D + +KQ +++ ++LE+ L
Sbjct: 4224 KLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQ 4283
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIK 471
+A ++ K +E L++ KE++DL + E T + ++ + D +
Sbjct: 4284 READEIRKIKEETQNERQSLEKMTKALIKEREDL-VHLAEYTKREKEML----DEMQVAN 4338
Query: 470 EAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISEDSTTNIQVD 315
++ M+D + E++ + S++T DI + + ED +Q +
Sbjct: 4339 KSSMADLQREKRIL--EEMRENISKQTE--DIENEKEKSKLREDELKKLQTE 4386
Score = 94.4 bits (233), Expect = 4e-16
Identities = 139/601 (23%), Positives = 252/601 (41%), Gaps = 10/601 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDR-------NIVEADKQAL 2124
+N +E K+ L+N + E + +L E N +D+K + R N + +++ L
Sbjct: 9653 KNQIEQEKKDLQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDL 9712
Query: 2123 ENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVF--EAAIATLNDELLNEK 1950
EN + E + +E + ++ I + D + +S+ ++ E I +ELL K
Sbjct: 9713 ENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMK 9772
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDL 1770
+ + + +E Q L+ DLE AK E++R++D II + ++ ++
Sbjct: 9773 VE---MGRTKEEIEKESQRLQDATIDLENAKA----EIQRQEDKFEDIIDIKIQEKEREI 9825
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1590
K Q D+E + V +LE+ + + + Q+ +D K L K
Sbjct: 9826 KI---QLDKETKRLS------------EEIELKVKDLEMEMADMKRQKQEIEDTKGLLEK 9870
Query: 1589 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ K+ + + LE + L RE+++ ER+ NL +K + E+LRKE
Sbjct: 9871 E-------KQELKQEKKELEDQMMDLT----REKQETEEERN--NLMALKN-QLEDLRKE 9916
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ EK LEK+ +E + ++++ + K +K +L +
Sbjct: 9917 NE-----------IVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEKESLEQQRFE 9965
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
E +KQ E + + + D L R+L + K LEK + N+E
Sbjct: 9966 TEQQKQMLEISTTKMMEEKNEMAD-LSRELQKA---KDELEK---------IAYKTNKER 10012
Query: 1049 HEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 870
HE E +++A ELH + + ++ + Q+++ K + +E ++
Sbjct: 10013 HEVE---QMQA-------ELHSQ----------IQAIEQQGQIMQDKQNHLEEKELSIQR 10052
Query: 869 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKK 690
+ ++ N F E++ L V + KR DLE DIE+ K N + + L+K
Sbjct: 10053 KEEEIKIGNTEFQIEQEHLNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEK 10108
Query: 689 RISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLE 513
SELE D+ IW + L E L + KEK+ LEK +EL SK E
Sbjct: 10109 IRSELENE-----------KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKRE 10157
Query: 512 K 510
+
Sbjct: 10158 Q 10158
Score = 94.4 bits (233), Expect = 4e-16
Identities = 135/648 (20%), Positives = 285/648 (43%), Gaps = 52/648 (8%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVE--------- 2142
I +RN LE K L + E + L+ ++ +K I ++ IVE
Sbjct: 10464 IEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQ 10523
Query: 2141 -------ADKQALENK-VADFEATIATLNDELLNEKDDKKCIVEADK------QALESKV 2004
++ ALE + + D + +A EL N+ + + + EA K + E+ +
Sbjct: 10524 RNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHL 10583
Query: 2003 SVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN---DELE 1833
+ I ++ +E +K+D + I N+ KQ L+ K LE + +N + +
Sbjct: 10584 QRDKKEIKSIIEETSRQKEDLEKISTGMNV---QKQELKNKKDTLEQEREEINHKWTQFQ 10640
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEV 1653
++ D+ +A ++K ++ +++ K +R +++N I ++
Sbjct: 10641 QRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHE---INQKIE 10697
Query: 1652 NILILHEELQKEKDDKTAL-IKDLVAAEPGKRTVNEIV---SHLESKSRSLKEHF-LREE 1488
+ L E++ KEK+ A+ IK + E + +E+V + ++ + + L + + E+
Sbjct: 10698 ELQTLQEQIMKEKEKAEAMTIKLKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQ 10757
Query: 1487 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 1308
E E LE+ S + K E+E R E D K + + EK +EK+ +
Sbjct: 10758 EKEDLEKMKSEIMTQKQEMEKE-RSELDNKI------QQTDLEKHDIEKSKEIVEKLMFE 10810
Query: 1307 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL--------DLEPTIPSLNDAL 1152
+ HE +L+KE++D E +K E+ +L + I ++N+ +
Sbjct: 10811 VEEQRHEIQLQKEELD----------IERQKIADEQDLLIQNKSELQNENERIRNINEVI 10860
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 972
+++ + + + LEK +++ S+T+ + ++E K+ N +L K++D
Sbjct: 10861 KKERETLKEMEAHLEKEKEEMK----SITEETRRQKEDLE-KMSTDIKEQNQDLMKQRDL 10915
Query: 971 KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 792
E D++H E L+ ++ + + + ++ + ++ + + ER LE K
Sbjct: 10916 LEQEKEDINH---EWTQLQQRIDEFD---AQVSKQKEEDLTKQKEMKEERKSLEETK--- 10966
Query: 791 EKRVLDL--EATIHDIEMKTGKDDDYN------EAEKQTLKKRISELEEAISILTDKAKK 636
R++++ +A + DI+ + K+++ E + + L + SEL+ S + + KK
Sbjct: 10967 -ARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMDGKELDRIKSELKRERSEIDHEQKK 11025
Query: 635 LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK-----LEKC 507
L D I E L++ ++ K++Q +E+ EL +K +EKC
Sbjct: 11026 LNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKC 11073
Score = 92.8 bits (229), Expect = 1e-15
Identities = 132/673 (19%), Positives = 297/673 (44%), Gaps = 31/673 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENK-------VGDFEAAIATLNDELLNE----KDDKKCIVNDR-N 2151
++N R++LE ++ + +K + +F+A ++ ++ L + K+D+K + + N
Sbjct: 11187 LMNQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 11246
Query: 2150 IVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN 1971
++E +A ++ + N+E E+++ + IVE +++ L S E + ++
Sbjct: 11247 VIEMKTKAEPEEIKKEKEKE---NEEEEEEEEEIRVIVETERKELYQIKSELERVRSEID 11303
Query: 1970 DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE-----LERKKDDNNAI 1806
E D K I ++ LE K + + +E ++ L+++ LE+ + +
Sbjct: 11304 HEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKE 11363
Query: 1805 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEEL 1626
I + L + + + D + +E D+ E N+L+ ++
Sbjct: 11364 IVEKLMVEVEEQRKDIQLQKEELDIERQKIAD-----------------EQNLLVQNKAK 11406
Query: 1625 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKS---RSLKEHFLREEEDEVLERSASN 1455
+ ++++ + + + E + T+ E+ HL+ + RS+ E R +ED LE+ +++
Sbjct: 11407 LQNENERIKKVDEEIKKE--RETLREMEIHLKKEKEELRSIIEETQRRKED--LEKMSTD 11462
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR 1275
+ K L+ ++D L+E E E+ E T L++R D + E+L
Sbjct: 11463 INEQKL----HLKNQRD----LLEQ----EREEINHEMTQLQQRIDEFDAQVSKQREDLT 11510
Query: 1274 KEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCS 1095
K+++ E E++ E+T + + + +L +M EK+ ++
Sbjct: 11511 KQEM------------EEERKSLEETKARI------IEMKTKAELQEIMQEKEEEDEE-- 11550
Query: 1094 DLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLE 915
E + + +E ++ + E K S + H E K DDK+ I + + ++ + +
Sbjct: 11551 --EMRVIVEMEREELNQIKSELKRVRSEIDH--EQKKLNDDKKIIEQEKEDLEKMKSEIM 11606
Query: 914 SKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 735
++ ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 11607 TQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQ 11666
Query: 734 KDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
K D N+A+ Q +RI E++E I K K+ LK++ L + E + +
Sbjct: 11667 KIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSVIE 11722
Query: 572 ES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFS 399
E+ ++K+DLEK ++ +K + + RD L +E + W + + F
Sbjct: 11723 ETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDEFD 11775
Query: 398 RKTSPL---DITK 369
+ S D+TK
Sbjct: 11776 AQVSKQKEEDLTK 11788
Score = 92.8 bits (229), Expect = 1e-15
Identities = 128/675 (18%), Positives = 276/675 (40%), Gaps = 35/675 (5%)
Frame = -2
Query: 2288 NDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N R++LE ++ + +++ + I + ++ +++D + + + E K E K
Sbjct: 11472 NQRDLLEQEREEINHEMTQLQQRIDEFDAQVSKQRED----LTKQEMEEERKSLEETKAR 11527
Query: 2108 DFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEKDD 1944
E E++ EK+++ + IVE +++ L S + + ++ E DD
Sbjct: 11528 IIEMKTKAELQEIMQEKEEEDEEEMRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDD 11587
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDKRI 1779
KK I ++ LE K + + +E ++ L++ +LER +N+ I + L ++
Sbjct: 11588 KKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKV 11647
Query: 1778 SDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTA 1599
+ + D + +E D+ E QK D++
Sbjct: 11648 EEQRKDIRLQKEELDI---------------------------------ERQKIADEQGL 11674
Query: 1598 LIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEEL 1419
++++ + + E+ ++ + +LKE E L
Sbjct: 11675 VVQNKAKLQNENERIKEMDEEIKKEKETLKE------------------------MEAHL 11710
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTM---DAIHEE-----------E 1281
RKEK+ +++E E +K+ LEK + N D M D + +E +
Sbjct: 11711 RKEKEEMRSVIE--ETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWTQLQ 11768
Query: 1280 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKR 1101
R ++ D + E +K+ E+ E I + + + +++ EK+ E+
Sbjct: 11769 QRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEE- 11827
Query: 1100 CSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV 921
E A + +E + +I+ +LE + E K DDK+ I + + ++ +
Sbjct: 11828 ----EVMRAKVEMKKEELD-QIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSE 11882
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
+ + ME S L+N+++Q + N ++ ++ + +E++ D+ +++++
Sbjct: 11883 IMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIE 11942
Query: 740 TGKDDD------YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 579
K D N+A+ Q +RI E++E I K K+ LK++ L + E +
Sbjct: 11943 RQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHLRKEKEEMRSV 11998
Query: 578 NKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQG 405
+E+ ++K+DLEK ++ +K + + RD L +E + W + +
Sbjct: 11999 IEETQRRQKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHKWTQLQQRIDE 12051
Query: 404 FSRKTSPL---DITK 369
F + S D+TK
Sbjct: 12052 FDAQVSKQKEEDLTK 12066
Score = 91.7 bits (226), Expect = 3e-15
Identities = 140/737 (18%), Positives = 310/737 (42%), Gaps = 97/737 (13%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+++ +V+++ +L + L+NK + D+ +++ +
Sbjct: 10537 ERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEE 10596
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDE 2073
+ D E +N + K+ K + +R + + ++ +F+A + +E
Sbjct: 10597 TSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEE 10656
Query: 2072 -LLNEK---DDKKCIVEADKQALESK---------VSVFEAAIATLNDELLNEKDDKKCI 1932
L N+K +++KC+ E + + +E K ++ + TL ++++ EK+ + +
Sbjct: 10657 DLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEELQTLQEQIMKEKEKAEAM 10716
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADA 1758
L+ ++ L+ ++L KT ++ E ++ DD I K+ L+K S++
Sbjct: 10717 TIK---LKMEREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10773
Query: 1757 PQRDQE-DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDD------KTA 1599
+ ++E +++ I +IV L + E+Q +K++ K A
Sbjct: 10774 QEMEKERSELDNKIQQTDLEKHDIEKSKEIVEKLMFEVEEQRHEIQLQKEELDIERQKIA 10833
Query: 1598 LIKDLVAAEPGK--------RTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIM 1443
+DL+ + R +NE++ + ++ H +E+E+ M
Sbjct: 10834 DEQDLLIQNKSELQNENERIRNINEVIKKERETLKEMEAHLEKEKEE------------M 10881
Query: 1442 KAIREEELRKEKDGKSA----------LVENGEGCEAEKQGL--EKTVLERRASNLDTM- 1302
K+I EE R+++D + L++ + E EK+ + E T L++R D
Sbjct: 10882 KSITEETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDINHEWTQLQQRIDEFDAQV 10941
Query: 1301 ------DAIHEEELRKEKVD----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
D ++E+++E+ K+ + E E E EK + E + +
Sbjct: 10942 SKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDIKKEKEKEEEEEEMRVKVEMD 11001
Query: 1151 QRDLDRVMAE-------------------------KQALEKRCSDLEAKNASLTDNQEGH 1047
++LDR+ +E KQ LEK S++ + + + +
Sbjct: 11002 GKELDRIKSELKRERSEIDHEQKKLNDDKKIIEQEKQNLEKMKSEIMKQRQQMEEERSEL 11061
Query: 1046 EAEIERK-LEASNLTHNDELHKE-----KDDKESIMNDLDHVKAERQVLESKVSDMETTY 885
E +I++ +E ++ ++ E+ ++ ++ K I + + ERQ + + +
Sbjct: 11062 ENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNK 11121
Query: 884 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------D 723
S L NE ++ + NE ER+ L+ ++ LEK+ ++++ E + K+D D
Sbjct: 11122 SELQNENERIRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSE--ETRRLKEDLEKMSTD 11179
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQE-DLNKESKEKQD-- 552
N+ K + +R LE+ + K K+L + I+ + ++V++ +E DL KE K+D
Sbjct: 11180 VNKQNKDLMNQR-DLLEQEREEINHKWKQLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRK 11238
Query: 551 ----LEKRVLELTSKLE 513
+ V+E+ +K E
Sbjct: 11239 SLEETKANVIEMKTKAE 11255
Score = 91.3 bits (225), Expect = 4e-15
Identities = 146/692 (21%), Positives = 284/692 (41%), Gaps = 60/692 (8%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQAL---ENK 2241
+R LE LE K + + I +NILE K L + +
Sbjct: 13840 ERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTEELKNILEREKSELYQEKAQ 13899
Query: 2240 VGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNE 2061
V + + T+ + +E ++ +C+ RN +E +K+++ ++++ + I L E+ +E
Sbjct: 13900 VQQQKHEMETIRKTMKSEMENLECL---RNELEDEKKSMLSRLSMEKHEIDKLKTEIQSE 13956
Query: 2060 KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYK 1881
K+ +E +K+ L+ E+ L++ + DK I +++ LE K L+ K
Sbjct: 13957 KES----IEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRK 14012
Query: 1880 VADLE-----AAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIX 1716
L+ A + T + K D++ ++ L +D++ A + E D+ L
Sbjct: 14013 AEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQA--KILESDVQLLQT 14070
Query: 1715 XXXXXXXXXXXXXKIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNE 1548
+ +LE N L L +EL+KEK +I D+ + +
Sbjct: 14071 EKEILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------D 14122
Query: 1547 IVSHLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGE 1374
V+ L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 14123 AVASLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENM 14181
Query: 1373 GCEAEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTE 1242
+ + ++ + E R D + DA+ + +EL K D E
Sbjct: 14182 KMRNDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKE 14241
Query: 1241 NGEGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA---- 1083
+ E E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 14242 HVEKEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADD 14301
Query: 1082 --------KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH 942
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 14302 IKTLVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQ 14361
Query: 941 ---------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGL 792
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +
Sbjct: 14362 KEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKII 14421
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 612
E +EKQ++++ +EL K+L +++ +
Sbjct: 14422 E-------------------------SEKQSIERERAEL-----------KRLKEEVEVQ 14445
Query: 611 LSEVTELQEDLNKESKEKQDLEKRVLELTSKL 516
E T LQ+D N KEK+ LE T ++
Sbjct: 14446 -HERTLLQQDKNMIQKEKEHLEGEKARTTEEI 14476
Score = 90.1 bits (222), Expect = 8e-15
Identities = 141/644 (21%), Positives = 275/644 (42%), Gaps = 49/644 (7%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN- 2118
I NDR E L+N+ D E + + DE N + K+ + +DR+ +E ++ LE
Sbjct: 2638 IDNDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVQKQRLESDRDTLEKERFDLEKT 2697
Query: 2117 --KVADFEATIATLND-------ELLNEKD---DKKCIVEADKQALESKVSVFEAAIATL 1974
++ D E + + + E+ E++ K + K+ LE + FE A +
Sbjct: 2698 KTEMKDLEKQLESQSRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 1973 N-DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERK--KDDNNAI- 1806
+ E L E+ +K+ I D+ + ++ E + L K N+EL+++ +D+ + I
Sbjct: 2758 SLREELEEQSEKEGI--DKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE 2815
Query: 1805 -IKKALDKRISDLKADAPQRDQEDDMN---ALIXXXXXXXXXXXXXXKIVSNLEVNILIL 1638
IK L K D + ++D E+D ++ + + E N+ +L
Sbjct: 2816 QIKAELQKEAKD--TEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLRVL 2873
Query: 1637 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSA 1461
+ L+ ++D L K+ + + ++ LES++R + ++E E+LE+
Sbjct: 2874 KQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1460 SNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 1290
L+ K E+E KEK S E E ++E++G+ KT R MD
Sbjct: 2931 LTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIKKEMD--- 2981
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL 1110
EL++ +++ EN E +KQ ++ + D++ K L
Sbjct: 2982 --ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKIEQIKAEL 3018
Query: 1109 EKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDKESIMNDL 948
+K D E + + ++ +E + ++ +E S DE + K+ + +D
Sbjct: 3019 QKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDR 3078
Query: 947 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 768
D ++ ER LE ++M L ++++Q ER+ LE +K L K+ DLE
Sbjct: 3079 DTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLE 3138
Query: 767 ATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL------TDKAK 639
E + +D ++E++ +K+ + ELE+ L + K
Sbjct: 3139 KERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQENNELQK 3198
Query: 638 KLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 510
K+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3199 KIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 89.0 bits (219), Expect = 2e-14
Identities = 139/671 (20%), Positives = 284/671 (42%), Gaps = 55/671 (8%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R I+E ++ L + + + ++ E DDKK I ++ +E K + +
Sbjct: 11553 RVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQM 11612
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALES---KVSVFEAAIATLNDELLNEK----DD 1944
E + L D + + D ++ +E K+ ++ KV I +EL E+ D+
Sbjct: 11613 EEERSEL-DNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADE 11671
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---ELERKKDDNNAIIKKALDKRISD 1773
+ +V ++ L+ + ++ +++ K TL + L ++K++ ++I++ ++ D
Sbjct: 11672 QGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKED 11731
Query: 1772 LK---ADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
L+ D +++Q+ L+ + L+ I ++ K+K++
Sbjct: 11732 LEKMSTDVNKQNQD-----LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED- 11785
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE---EEDEV-----------LERS 1464
L K E K + +E K+++ E +E EE+EV L++
Sbjct: 11786 -LTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQI 11844
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIH 1290
S L +++ + E +K D K + + E E K + ++ +E S LD + I
Sbjct: 11845 KSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELD--NKIK 11902
Query: 1289 EEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDLEPT--------IPSLNDALQR 1146
+ +L + ++ S E E+Q + K LD+E + LQ
Sbjct: 11903 QTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQN 11962
Query: 1145 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-- 972
+ +R+ + ++K L+ A L +E E+ +E + ++L K D
Sbjct: 11963 ENERIKEMDEEIKKEKETLKEMEAHLRKEKE----EMRSVIEETQRRQKEDLEKMSTDVN 12018
Query: 971 --KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 798
+ +MN D +K ER+ + K + +LQQ++D+ +A ++++ + KQ
Sbjct: 12019 KQNQDLMNQRDLLKQEREEINHKWT-----------QLQQRIDEFDAQVSKQKEEDLTKQ 12067
Query: 797 G-LEKRVLDLEAT-IHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD 624
+E+ LE T I IEMKT + + + EK+ E EE + + K+ L
Sbjct: 12068 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKE------KEEEEVMRAKVEMKKEELDQ 12121
Query: 623 INIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I L SE+ Q+ LN + K EK+DLEK E+ + ++ + + I++
Sbjct: 12122 IKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELENKIRQ 12181
Query: 467 AWMSDCMVPDN 435
++ C + ++
Sbjct: 12182 TYIEKCDIENS 12192
Score = 88.2 bits (217), Expect = 3e-14
Identities = 144/674 (21%), Positives = 290/674 (43%), Gaps = 38/674 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
K + VV + E KQ +E++ E A + I DR E
Sbjct: 2984 KQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIEKDRRNNEEMV 3043
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD--------------KQALE 2121
L+N+ D E + + DE N + K+ + +DR+ +E + K+ LE
Sbjct: 3044 IKLQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKERFDLEKTKTEMGNLKKQLE 3103
Query: 2120 NKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLN-DELLNEKDD 1944
+++ E + + E + K + K+ LE + FE A ++ E L E+ +
Sbjct: 3104 SQIRQHEIQLVEIQKER-EILEQLKINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSE 3162
Query: 1943 KKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKA 1764
++ I N R ++ LE +L AK N+EL++K II+ DK I +KA
Sbjct: 3163 REGIDNTRTRIKQEMDELEKTRQNL--AKEQENNELQKK------IIEDERDK-IEQIKA 3213
Query: 1763 DAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+ + ++ + + N N+ +L+K++++ +L ++L
Sbjct: 3214 ELKKEAEKTKLE-------------------LQNERQNLEEAGTKLKKDRENVESLAEEL 3254
Query: 1583 VAAE---PGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRK 1413
+ + E+ ++ ++E L E L+++ +++A K E +L +
Sbjct: 3255 GRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTDIAGAKEDLENQLLE 3309
Query: 1412 EKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE-EELRKEKVDKSALTENG 1236
E++ V+ E +AEK L L ++ + +D +++ E+LR +V+ L
Sbjct: 3310 EREKNK--VKQAE-IQAEKDML---YLLKQGISEQQVDIVNKTEQLRLREVELEQLQALI 3363
Query: 1235 EGCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMA----EKQALEKRCSDLEAKN 1077
+ E + K +++ + + D LQR+++++M ++ LEK S++ A+
Sbjct: 3364 YRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKDRANLEKEKSEMIAQK 3423
Query: 1076 ASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDM 897
+ IE + + N T+ E+ +++ E M +L + K Q ++K+ M
Sbjct: 3424 HQMDIELNKERGLIEERTQMLN-TYEKEMDQKRTALEVEMKELKYHKQAIQEEKNKLQQM 3482
Query: 896 ETTYSTLNNELQQKMDD----NEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
+ ELQ++ DD E NER LE + + LEK DL D + K +
Sbjct: 3483 KI-------ELQREADDIKKLKEKTRNERQSLEKMAENLEKEKDDLAHLAEDTKRKDDEM 3535
Query: 728 DDYNE---AEKQTLKKRISELEEAI-----SILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+E A+ Q K + ++ E++ I ++K K +L++ ++ ++Q ++N+
Sbjct: 3536 KVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEKKKMILRE-----DKLQQMQAEINR 3590
Query: 572 ESKEKQDLEKRVLE 531
+ E D +K ++E
Sbjct: 3591 QQTE-MDTKKSIIE 3603
Score = 88.2 bits (217), Expect = 3e-14
Identities = 131/622 (21%), Positives = 266/622 (42%), Gaps = 27/622 (4%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVG-------DFEAAIATLNDELLNEKDDKKCIVNDRNIVEAD 2136
I+ R +E + L+NK+ D E + + ++ ++ +K I + ++ +
Sbjct: 11330 IMKQRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIE 11389
Query: 2135 KQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLN 1956
+Q K+AD + + +L NE + K + E K+ E+ + + L
Sbjct: 11390 RQ----KIADEQNLLVQNKAKLQNENERIKKVDEEIKKERET--------LREMEIHLKK 11437
Query: 1955 EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDK 1785
EK++ + I+ + + K+ LE D+ K L ++ LE+++++ N + + L +
Sbjct: 11438 EKEELRSIIEET---QRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMTQ-LQQ 11493
Query: 1784 RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK 1605
RI + DA Q +D+ I + + + +E ++E +++
Sbjct: 11494 RIDEF--DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEE 11551
Query: 1604 TALIKDLVAAEPG--KRTVNEIVSHLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAI 1434
+I ++ E K + + S ++ + + L + + E+E E LE+ S + +
Sbjct: 11552 MRVIVEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQ 11611
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
EEE R E D K +++T LER +++ I ++ + K + +
Sbjct: 11612 MEEE-RSELDNK----------------IKQTDLERH--DIENSKEIVQKLMVKVEEQRK 11652
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 1074
+ E + E+Q + D + + LQ + +R+ + ++K L+ A
Sbjct: 11653 DIRLQKEELDIERQ----KIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEA 11708
Query: 1073 SLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD----KESIMNDLDHVKAERQVLESKV 906
L +E E+ +E + ++L K D + +MN D +K ER+ + K
Sbjct: 11709 HLRKEKE----EMRSVIEETQRRKKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKW 11764
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG-LEKRVLDLEAT-IHDIEMKTGK 732
+ +LQQ++D+ +A ++++ + KQ +E+ LE T I IEMKT
Sbjct: 11765 T-----------QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKT 11813
Query: 731 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKESK 564
+ + + EK+ E EE + + K+ L I L SE+ Q+ LN + K
Sbjct: 11814 EPEKIKKEKE------KEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKK 11867
Query: 563 ----EKQDLEKRVLELTSKLEK 510
EK+DLEK E+ + ++
Sbjct: 11868 MIEQEKEDLEKMKSEIMKQRQQ 11889
Score = 87.8 bits (216), Expect = 4e-14
Identities = 143/649 (22%), Positives = 278/649 (42%), Gaps = 45/649 (6%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEA---AIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVA 2109
N+++ ++ E K + + A+ +N EL + + K + + EAD Q +NK
Sbjct: 13821 NLIKKQQKEFETKENEMQRERKALEKMNAELERKSTELKNKIEKVTVWEADLQKEKNKTE 13880
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
+ + + EL EK V+ K +E+ ++ + L + L NE +D+K +
Sbjct: 13881 ELKNILEREKSELYQEKAQ----VQQQKHEMETIRKTMKSEMENL-ECLRNELEDEKKSM 13935
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDE---LERKKDDNNAIIKKALDKRISDLKADA 1758
R L K ++ ++++ K ++ +E L++ KD+N + + LD I + D
Sbjct: 13936 LSR--LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENES-KRTQLDNTIEKMNMDK 13992
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVA 1578
+E D +I ++L+ L EE++K + + +D
Sbjct: 13993 LSIQREKD----------------SLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKI 14036
Query: 1577 AEPGKRTVNEIVS---HLESKSRSLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKE 1410
+ + E+ S +E +++ L+ L + E E+LE+S + +++ E+L K+
Sbjct: 14037 LDDDREKEEELRSMRADIERQAKILESDVQLLQTEKEILEKSKTENDLLR----EDLEKQ 14092
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
+ ++ EK LE+ + + D + ++ E K+ K+ TE E
Sbjct: 14093 RKRNDLTLQE---LRKEKMALEQMITD-ITKEKDAVASLQNEVSLKQHELKNKETELDE- 14147
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+++ + + LE S N Q+++D + E K +DLE+ L + +
Sbjct: 14148 ---QRKEMDDLRMQLEMRQNSTNKQ-QQEVDVFIVENM---KMRNDLESMKTLLDEERRQ 14200
Query: 1049 HEAEIERKLEASNLTH---------NDELHKEKDDKESIMNDLDHVKAERQ---VLESKV 906
+ I+ + N+ H DEL K D I + +HV+ ER+ VL ++
Sbjct: 14201 LQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD---IKTEKEHVEKEREEIDVLNKEI 14257
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE--MKTGK 732
+ +LN E+ E F E G A + LE+ DL A DI+ ++T K
Sbjct: 14258 IKSKEELQSLNLEI-------EMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQTEK 14310
Query: 731 DDDYNEAEKQT-------LKKRISELEEAIS-------------ILTDKAKKLLKDI-NI 615
+ EK+T L+K+ +ELEE + I+ DK +K ++DI +
Sbjct: 14311 QMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDIMTV 14370
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
SE L+++ ++ +K L ++V +LE+ + RD + K+
Sbjct: 14371 IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKK 14419
Score = 87.4 bits (215), Expect = 5e-14
Identities = 127/646 (19%), Positives = 279/646 (43%), Gaps = 58/646 (8%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
++ KQ ++ K A+ L K+ ++ I ++ +E +K ++ + +
Sbjct: 10173 IQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKLEEEKLLVQIEAENLNKV 10232
Query: 2093 IATLNDELLNEKDDKKCIVEAD----KQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
+ E + + +K I EAD K+ E+ E + +++ N ++ K +
Sbjct: 10233 L-----EEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQIQNNENAKHLLEQ 10287
Query: 1925 DRNILEAAKQALEYKVADL-----------EAAKTTLNDELERKKDDNNAIIKKA--LDK 1785
+R ++ KQ L+ + DL E +K +L++E + + N I+++ L+K
Sbjct: 10288 ERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKANEILRQRDDLEK 10347
Query: 1784 RISDL-----KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE--- 1629
D+ K D Q + +++ A+ K LE ++ ++EE
Sbjct: 10348 EKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLEESLRAINEEKGD 10407
Query: 1628 ---LQKEKDDKTALIKDL-VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE-VLERS 1464
++ + + + I+++ V A+ ++ +++I S LE + + + D ++E+
Sbjct: 10408 LEIMRADYEKQEQQIEEMRVEAKMERKELDQIKSELEKDKTEIDYEWKKLNNDRNMIEKE 10467
Query: 1463 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDTMD--- 1299
++L MK+ + ++ +D +S L + + EK +EK ++ER + ++
Sbjct: 10468 RNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVERLMAEVEEQRNDF 10527
Query: 1298 AIHEEELRKEK---VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-------Q 1149
+ +EEL E+ VD+ L CE E Q + + ++E + + + L Q
Sbjct: 10528 KLKKEELALERQNIVDEKYLLAQ---CETELQNKSEQIRNMEEAVKNERETLKETEAHLQ 10584
Query: 1148 RD-------LDRVMAEKQALEKRCSDLEAKNASLT---DNQEGHEAEIERKLEASNLTHN 999
RD ++ +K+ LEK + + + L D E EI K +
Sbjct: 10585 RDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEINHKWTQFQQRID 10644
Query: 998 DELHKEKDDKESIMNDLDHVKAERQVLES---KVSDMETTYSTLNNELQQKMDDNEAFLN 828
+ + + KE + + ++ ER+ LE K+ +M+T ++E+ QK+++
Sbjct: 10645 EFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEINQKIEE------ 10698
Query: 827 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 648
L+ +++ + K EA ++M E++ L + SEL + +
Sbjct: 10699 ----LQTLQEQIMKEKEKAEAMTIKLKM-----------EREDLDQIKSELVREKTEVDH 10743
Query: 647 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
+ KKL DI + E +L++ ++ +KQ++EK EL +K+++
Sbjct: 10744 EQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERSELDNKIQQ 10789
Score = 85.5 bits (210), Expect = 2e-13
Identities = 144/713 (20%), Positives = 299/713 (41%), Gaps = 118/713 (16%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
++N R++L+ ++ + +K + I + ++ +K++ + + + E K E K
Sbjct: 11746 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEED--LTKQKKMEEERKSLEETK 11803
Query: 2114 VADFEATIATLNDELLNEKDDK-----KCIVEADKQALESKVSVFEAAIATLNDELLNEK 1950
+ E T +++ EK+ + + VE K+ L+ S E + ++ E
Sbjct: 11804 IKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLN 11863
Query: 1949 DDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND-----ELERKKDDNNAIIKKALDK 1785
DDKK I ++ LE K + + +E ++ L++ +LER +N+ I + L
Sbjct: 11864 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMV 11923
Query: 1784 RISDLKADAPQRDQE---------DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
+ + + D + +E D+ ++ ++ ++ L E
Sbjct: 11924 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKE 11983
Query: 1631 ---ELQKEKDDKTALIK----------------------DLVAAEPGKRTVNEIVSHL-- 1533
L+KEK++ ++I+ DL+ + E ++H
Sbjct: 11984 MEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEINHKWT 12043
Query: 1532 --------------ESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGK 1398
+ K L + EEE + LE + + MK E E+++KEK+ +
Sbjct: 12044 QLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE 12103
Query: 1397 SALVENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEE--------LRKEKVD---- 1260
V + E +K+ L+ K+ LER S +D HE++ + +EK D
Sbjct: 12104 EEEVMRAK-VEMKKEELDQIKSQLERVRSEID-----HEQKKLNDDKKMIEQEKEDLEKM 12157
Query: 1259 KSALTENGEGCEAEKQGPEKTVLDL---EPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
KS + + + E E+ E + + I + + +Q+ + V +K ++ + +L
Sbjct: 12158 KSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEEL 12217
Query: 1088 EAKNASLTDNQE---GHEAEIER------------KLEASNLTHNDE-LHKEKDDKESIM 957
+ + + D Q+ +++E++ K E L + L KEK++ +SI
Sbjct: 12218 DIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSIT 12277
Query: 956 N-------DLD----HVKAERQVLESKVSDMETTYSTLNN---ELQQKMDDNEAFLNER- 822
DL+ H+ ++Q L S+ +E +N+ +LQQ++D+ +A ++++
Sbjct: 12278 EETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVSKQK 12337
Query: 821 -DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDK 645
+ L K+ E R E + +EMKT + + + EK+ E E+ + + +
Sbjct: 12338 EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEKEK-----EEEEQEMRVKVEM 12392
Query: 644 AKKLLKDINIWL----SEVTELQEDLNKESK----EKQDLEKRVLELTSKLEK 510
+K ++ I L SE+ Q+ LN + K EK+DLEK E+ + ++
Sbjct: 12393 ERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQ 12445
Score = 85.1 bits (209), Expect = 3e-13
Identities = 128/613 (20%), Positives = 259/613 (42%), Gaps = 34/613 (5%)
Frame = -2
Query: 2261 KQALENKVGD-FEAAIATLNDELLNEKDDKKCIVN-DRNIVEADKQALENKVADFEATIA 2088
KQ + K+ D + + + D + + K ++ +++ +E K ++ ++ +FE +
Sbjct: 14924 KQPIVTKLEDTLTSEVQEMRDMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNME 14983
Query: 2087 -TLND---------ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
TL + +LL++KDD ++ + +E+ F+ IA L + K DK+
Sbjct: 14984 ETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKDKE 15043
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAA------------KTTLNDELERKKDDNNAIIKKA 1794
I N+ L+ +Q E + + + KT L D E+KK D ++ +K
Sbjct: 15044 NIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELEDSKEKKKPDRDSSLK-- 15101
Query: 1793 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEK 1614
++D AD+ + D E + L + V L EEL E
Sbjct: 15102 ----LTD--ADSAKTDGEREAQTL-----------ETKVQDVLQLTDYTTQDQEELHDEM 15144
Query: 1613 DDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAI 1434
++K +I +L A+ + + L+ + RS +E + E LER ++L
Sbjct: 15145 ENKMKIILELNEAK-------KDLQKLKEECRSAEEE--KSVIMESLERRRNSL------ 15189
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLERRASNLDTMDAIHEEELRKEKVDK 1257
E+++ E + +++ + E Q +E K ++ R+ + ++ ++
Sbjct: 15190 --EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQIQQGQEATETT 15247
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPS----LNDALQRDLDRVMAEKQALEKRCSDL 1089
+T+ E + K+ + TV LE T+ S + D+L ++++ V K ++ L
Sbjct: 15248 GHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVARMKTIMKMEKDQL 15307
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD----HVKAERQV 921
E + + E E +E +E + + ++L + DKE + N LD ++ +
Sbjct: 15308 EQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKLLQLTHDKEDLSNTLDKKNKEIENNTET 15366
Query: 920 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 741
K++ +ETT + + K+ +E +L L+ T + E++
Sbjct: 15367 SLKKIAQLETTIVLMKKD---------------------KENIENELLQLKQTEQEREIQ 15405
Query: 740 TGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK 564
G DD NE EK K +ELE+ + KK +D ++ L++ + D +E++
Sbjct: 15406 RGTDDTSNEREKYDEKVTYKTELED-----NKEKKKPDRDSSLKLTDADSAKTDGEREAQ 15460
Query: 563 EKQDLEKRVLELT 525
+ + VL+LT
Sbjct: 15461 TLETKVQDVLQLT 15473
Score = 84.0 bits (206), Expect = 6e-13
Identities = 125/589 (21%), Positives = 252/589 (42%), Gaps = 18/589 (3%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDEL-LNEKDDKKCIVNDRNIVEADKQALENKVADFE- 2100
+E KQ ++N+ + A L +E NE+ +++ + N + A + + DFE
Sbjct: 7414 IEKKKQDMQNERQKLDDMAARLQEERRTNERLNEEINIQKVN-QQKQATAFQMEKTDFER 7472
Query: 2099 --ATIATLNDELLNEKD-DKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIV 1929
I N EL ++++ +KK I E K+ TL + N + I
Sbjct: 7473 IKTEIDQANKELADQQEKNKKTITEMQKER------------ETLEEMRANISKQVETIT 7520
Query: 1928 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA-LDKRISDLKADAPQ 1752
N+ L + + L D+ L + E + N +++ LD+R SD+ D Q
Sbjct: 7521 NENKSLSSRESELAKLQEDI------LQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQ 7572
Query: 1751 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAE 1572
++ +D M+ ++N+E L + + + K D +L + A E
Sbjct: 7573 KEVDDLMD--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACE 7618
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
+ +NE +E + L ++ ++D++ ++R NL + K + E ++ + K
Sbjct: 7619 QLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKI 7678
Query: 1394 ALVENGEGCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGE 1233
+L G + +EK E+ ++E A+ LD + E + +E++D++
Sbjct: 7679 SLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKT 7738
Query: 1232 GCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE 1053
+ EKT DL+ T +N D + + ++ L K
Sbjct: 7739 YYTEDLFQEEKT--DLQKTKEEIN----YDREEIYRQRTELNK----------------- 7775
Query: 1052 GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 873
E E +++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + +
Sbjct: 7776 --EKETLKQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMM 7830
Query: 872 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ--- 702
E + D E NE+D L+ ++ ++K + +L+ E + + N+ +Q
Sbjct: 7831 KEKAELARDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTE 7884
Query: 701 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 561
+K + L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7885 EIKLKNDSLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7933
Score = 84.0 bits (206), Expect = 6e-13
Identities = 115/623 (18%), Positives = 262/623 (42%), Gaps = 6/623 (0%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
+ L E+ ++ K ++++ I +++ Q L + + L E+ N K DK +
Sbjct: 9072 VRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIENTKRDKSNL 9131
Query: 2039 VEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA 1860
E K LE K E+ L E + KK I ++ +E +++ +E ++ + E
Sbjct: 9132 -EKMKAELEEKQQEEESMREILQKEKEELEQLKKDINREKEDIEISRELVESEIYEGEVK 9190
Query: 1859 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 1680
T ++++ K++ + ++ L K+ + + D + M L
Sbjct: 9191 GFT---DVQKYKEELQIVTEELLTKKRN---LEQLNSDVQHLMQTLEEVDIQYIKKKAEL 9244
Query: 1679 XKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF 1500
I S ++ IL E+ +K+ ++ +I+++ + ++N + KE+
Sbjct: 9245 EHITSEIQKREQIL-EKQKKKLEENGWIIEEIEMMKVTLESINMEILQKREDMEKEKENL 9303
Query: 1499 LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRA 1320
RE+++ L R EL++++D VE+ ++ K ++ +
Sbjct: 9304 RREKQETELFRG-------------ELQRQRDE----VESSRQALIMEKDQFKLKIDHQR 9346
Query: 1319 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 1140
+ + A +E R E ++ + + E+ + +E + + + L ++
Sbjct: 9347 NEMSA--AFEKEHKRLENMENDLENQRAKLAESLNDAAK-----MEQKLQQMKNELNKEK 9399
Query: 1139 DRVMAEKQALEKRCSDLEAKNASLTDN----QEGHEAEIERKLEASNLTHNDELHKEKDD 972
++V KQ ++ +E + + ++GHE ++++K E + D+L ++ +
Sbjct: 9400 EQVEEMKQMVKTERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANS 9453
Query: 971 KESIMNDLD-HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG 795
+ + DL ++ +RQ +E ++MET +L+ ++ DD N+RD E
Sbjct: 9454 ESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTH 9513
Query: 794 LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINI 615
LE + +L D+E K + + +E K+ ++ + LE + K + K++
Sbjct: 9514 LELKREELVRETEDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMEN 9573
Query: 614 WLSEVTELQEDLNKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPD 438
SE +L ++ +LE RV +E L++ + + E MS+ + +
Sbjct: 9574 VHSERQKLLLLQGALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTE 9631
Query: 437 NWVPFEDLVQGFSRKTSPLDITK 369
+ L++ R+ L+I+K
Sbjct: 9632 Q-NEYRKLIEELQREKEQLEISK 9653
Score = 84.0 bits (206), Expect = 6e-13
Identities = 140/656 (21%), Positives = 289/656 (44%), Gaps = 72/656 (10%)
Frame = -2
Query: 2219 IATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCI 2040
IA + D+LL EK+D + N + + +++++ D + + N +LL K +
Sbjct: 13675 IADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTE---- 13730
Query: 2039 VEADKQALESKVSVFEAAIATLNDELL---NEKDDKKCIVNDRNILEA-AKQALEYKVAD 1872
++ ALE + + +N ++ E++ + ++ + E A+ ++ + D
Sbjct: 13731 IQVKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 13790
Query: 1871 LEAAKTTL----------NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMN 1728
+E+ K L N EL+ + ++ +IKK ++ + K + QR+++ + MN
Sbjct: 13791 IESVKVRLVTESNQIDKMNSELKTRSEELENLIKK--QQKEFETKENEMQRERKALEKMN 13848
Query: 1727 ALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG-----K 1563
A + + N + + +LQKEK +KT +K+++ E K
Sbjct: 13849 AELERKSTE----------LKNKIEKVTVWEADLQKEK-NKTEELKNILEREKSELYQEK 13897
Query: 1562 RTVNEIVSHLESKSRSLKEHF-----LREEEDEVLERSASNLAIMK-------------- 1440
V + +E+ +++K LR E ++ + S L++ K
Sbjct: 13898 AQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSRLSMEKHEIDKLKTEIQSEK 13957
Query: 1439 -AIREE-----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA------ 1296
+I EE +L+ E + K ++N EK ++K ++R +L+ + A
Sbjct: 13958 ESIEEEKKTLKQLKDENESKRTQLDN----TIEKMNMDKLSIQREKDSLEEIKADLQRKA 14013
Query: 1295 -IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 1119
+EE+RK S ++++ + + +++ E+ + + I L+ D+ + EK
Sbjct: 14014 EKLDEEMRKAVQITSQISQDAKILDDDRE-KEEELRSMRADIERQAKILESDVQLLQTEK 14072
Query: 1118 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
+ LEK S T+N E ++E++ + ++LT EL KEK E ++ D+
Sbjct: 14073 EILEK----------SKTENDLLRE-DLEKQRKRNDLT-LQELRKEKMALEQMITDITKE 14120
Query: 938 KAERQVLESKVSDMETTYSTLNNEL---QQKMDDNEAFLNER-DGLEAVKQGLEKRVLDL 771
K L+++VS + EL +++MDD L R + +Q ++ +++
Sbjct: 14121 KDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVEN 14180
Query: 770 EATIHDIE-MKTGKDDDYNEAEKQTLKKRISELEEAISIL----------TDKAKKLLKD 624
+D+E MKT D+ E++ L+ I E+ ++L TD+ +K D
Sbjct: 14181 MKMRNDLESMKTLLDE-----ERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTD 14235
Query: 623 INIWLSEVTELQED---LNKE-SKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 468
I V + +E+ LNKE K K++L+ LE+ ++ I G R + ++++
Sbjct: 14236 IKTEKEHVEKEREEIDVLNKEIIKSKEELQSLNLEI-EMFKQEIAGKRAQIESLEQ 14290
Score = 83.6 bits (205), Expect = 8e-13
Identities = 137/630 (21%), Positives = 251/630 (39%), Gaps = 35/630 (5%)
Frame = -2
Query: 2297 SIVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALEN 2118
++V + E KQ +E++ E A L E + + ++ I NDR E L+N
Sbjct: 2792 NVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQN 2851
Query: 2117 KVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKK 1938
+ D E + + DE N + KQ LES E L KD +K
Sbjct: 2852 EKKDIETSTDRIRDEEAN--------LRVLKQRLESDRDTLEKERFDLKKTNTEMKDLEK 2903
Query: 1937 CIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADA 1758
+ + E ++ + LE K TL+ + E + + + K+ D IS +
Sbjct: 2904 QLESQNRQHEIQLAEIQKEREILEQLKLTLSKQKEDLEKERDCFEKEKAD--ISLREELQ 2961
Query: 1757 PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNIL---ILHEELQKEKDDKTALIKD 1587
Q ++E + +V LE N L I+ +E K + K L K+
Sbjct: 2962 EQSEREGIGKTRVRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKE 3021
Query: 1586 LVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSASNLAIMKAIREEELRKE 1410
E +R + E R+ +E ++ + E + +E S IR+EE E
Sbjct: 3022 AEDTEKQRRDI-------EKDRRNNEEMVIKLQNEKKDIETSTDR------IRDEEANLE 3068
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSA------- 1251
K L + + E E+ LEKT E I + E++ ++ K
Sbjct: 3069 VQ-KQRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLK 3127
Query: 1250 --LTENGEGCEAEKQGPEKTVLDLEPT-----------IPSLNDALQRDLDRVMAEKQAL 1110
L++ E E E+ EK D+ + I + +++++D + +Q L
Sbjct: 3128 INLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNL 3187
Query: 1109 EKRCSDLEAKNASLTDNQEGHE---AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 939
K + E + + D ++ E AE++++ E + L EL E+ + E L
Sbjct: 3188 AKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKL----ELQNERQNLEEAGTKL--- 3240
Query: 938 KAERQVLESKVSDMETTYSTLNN-----ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 774
K +R+ +ES ++ L N E+Q+K +++ + ER +E L+K V D
Sbjct: 3241 KKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIE-----LKKTVTD 3295
Query: 773 LEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 603
+ D+E + ++ + N +AE Q K + L++ IS + + + E
Sbjct: 3296 IAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQLRLREVE 3355
Query: 602 VTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ +LQ + ++ E + K ++ +LE
Sbjct: 3356 LEQLQALIYRQQDEIEANRKAIINEKYRLE 3385
Score = 79.7 bits (195), Expect = 1e-11
Identities = 110/587 (18%), Positives = 242/587 (41%), Gaps = 7/587 (1%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
RN +EA K +EN+ + + D + K ++ + +++ + L KV
Sbjct: 14340 RNTIEAEKHQVENRKIMLDKQQKEVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQRE 14399
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + L ++ ++ ++ K I+E++KQ++E + A + L +E + + ++ + D
Sbjct: 14400 QEELERLLEKERDDIENCKKIIESEKQSIERE----RAELKRLKEE-VEVQHERTLLQQD 14454
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR-- 1749
+N+++ K+ LE + A L +E++RK + + + K+ KR + P+
Sbjct: 14455 KNMIQKEKEHLEGEKARTTEEIHNLKEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIE 14514
Query: 1748 -----DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDL 1584
+EDD+ ++ + +E+ K + + +++
Sbjct: 14515 IEDHLKKEDDVLREEIIKKQQTDASQKFQLKTTSRDAETQTSLDEITKTDERRQRALEET 14574
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKD 1404
VA + V ++ L S+ + +++H L LA MK I + E + K
Sbjct: 14575 VATTAKQPIVIKLEDTLTSEVQEMRDH---------LNNEIKELARMKTIMKMEKDQLKQ 14625
Query: 1403 GKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE 1224
KS + E E + +E+ + E+ + + H++E +DK + E
Sbjct: 14626 AKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSNTLDK-----KNKEIE 14677
Query: 1223 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE 1044
+ K + LE TI + + + ++ KQ ++R +++ K A +T
Sbjct: 14678 NNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQER--EIQRK-ADVTST----- 14729
Query: 1043 AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL 864
E+++ +T+ EL +D KE I D D E +S +D E TL ++
Sbjct: 14730 ---EKEMYTEKVTYKTEL---EDSKEKIKPDRDST-LELTDTDSAKTDGEREAQTLETKV 14782
Query: 863 QQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI 684
Q + + +++ L + K +L+L D+ Q LK+
Sbjct: 14783 QDVLQLTDDTTQDQEELHDEMENKMKIILELNKAKKDL---------------QKLKEEC 14827
Query: 683 SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 543
EE S++ + ++ + SEV L ++++ ++ K ++++
Sbjct: 14828 RSAEEEKSVIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQ 14874
Score = 77.8 bits (190), Expect = 4e-11
Identities = 127/620 (20%), Positives = 259/620 (41%), Gaps = 70/620 (11%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQA---LESKVSVFEA 1989
D+ + A+ Q L ++ + L E+ K+ I++ D++ L+ +V
Sbjct: 1361 DQEEMNAEMQRLILEIEHIREMLRGLKGEVEQNKE----IMKRDREEIRLLKIEVQRRRR 1416
Query: 1988 AIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDD-NN 1812
I ++++ E+D+ + + + + ++ LE ++ ++ ND +E+ ++D NN
Sbjct: 1417 EIEYREEKIMREQDELELM---SKMGQRQREELEERLEEVIKE----NDRVEQMREDVNN 1469
Query: 1811 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHE 1632
A+ K +D+ D++ QE A++ I S + L L
Sbjct: 1470 AL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKS-YRASDLELSA 1526
Query: 1631 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 1452
+QKE+ + K+++ E K +N+I +++ +E ++ E+E E +
Sbjct: 1527 SIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKLHEEEK-EMKTKRV 1582
Query: 1451 AIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------EKTVLERR------ 1323
++ R+ + KEK+ G A+ + KQ L EK+ LE +
Sbjct: 1583 SLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSKLEYKKPLEIK 1642
Query: 1322 -------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE------- 1203
AS D +I E + +++ ++ + C E+Q E
Sbjct: 1643 QVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQMAEIELSRDE 1702
Query: 1202 ------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
+T D+E + L++ D + K ++K DL+ + A +
Sbjct: 1703 LSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREK 1762
Query: 1058 QEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAERQVLESKVSDMET 891
+E E+E+ + N D E K E D K ++ + ++++A+R+++E + +E
Sbjct: 1763 EEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKMMEDEKRALEN 1822
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM------KTGKD 729
L E +ER +E + L++ +LE HD++ + KD
Sbjct: 1823 MKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKD 1882
Query: 728 -DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWLSEVTELQEDLNKE 570
++ E + TL K S++ E IS L + K +++ I I ++ ++Q DLN++
Sbjct: 1883 LENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQTDLNRQ 1942
Query: 569 SKEKQDLEKRVLELTSKLEK 510
KE QD++ V S+L+K
Sbjct: 1943 QKEMQDIQNAVFMEKSELKK 1962
Score = 76.6 bits (187), Expect = 1e-10
Identities = 135/691 (19%), Positives = 273/691 (39%), Gaps = 100/691 (14%)
Frame = -2
Query: 2282 RNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADF 2103
R ++E K+ALEN + + + N D+++ + N ++ + + LE K D
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 2102 EATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
+ + T + + ++ + + E +++K V E I+ LN + +KD+
Sbjct: 1870 QQ-LQTERSREIKDLENLRELNELTLNQIKTKSDVLEK-ISELNSQ---QKDE------- 1917
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAII--KKALDKRISDLKADAPQR 1749
+E K ++ + DL+ +T LN + + +D NA+ K L K ++ A Q
Sbjct: 1918 ---IENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQL 1971
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAE 1572
Q DM NL+ I+ ++LQ E+D L ++L + +
Sbjct: 1972 KQVGDMMQFTQNEK-------------DNLDRERAAIIEQKLQMERDMTHLLNRELESLK 2018
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKS 1395
K+ V LE SL E+ ++ LER + + + EE K +
Sbjct: 2019 LVKKEVLNEKRLLEDCRISLMRDMQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQ 2078
Query: 1394 ALVENGEGCE----AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK---------- 1257
L E+ E AEKQ LE +E + + M+ E + ++E VDK
Sbjct: 2079 TLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEI 2138
Query: 1256 ------------SALTENGEGC---------------EAEKQGPEKTVLDLEPTIPSLND 1158
+A+ EN + E+Q ++ V ++E +L D
Sbjct: 2139 TFKDLKADLQKEAAIVENQRQAVQKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-D 2197
Query: 1157 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER----KLEASNLTHNDEL 990
+Q ++D+ E+Q +E + +LE + + L ++++ + E+ + E + N EL
Sbjct: 2198 EMQMEVDK---ERQEVESKRDELEQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLEL 2254
Query: 989 HKEKDDKESIMNDLD---------------------------------HVKAERQVLESK 909
E KE + +L+ ++A++ K
Sbjct: 2255 QSENISKERTIFELEKEHLGLRENEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKK 2314
Query: 908 VSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD 729
++T L+++ + E+ E + +E K+ + ++ E+ + +EM+
Sbjct: 2315 AEYVKTARGRETTALEEQRQEMESLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAM 2374
Query: 728 DDYNEA----------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV------T 597
Y E ++Q +K I ++ + I + ++ K++ I V
Sbjct: 2375 KKYKEKLDKEYEDLQFQRQLFEKEIQQMRTELQIEAENIERKKKELEIQKPAVYTETYML 2434
Query: 596 ELQEDLNKESK--EKQDLEKRVLELTSKLEK 510
E Q+ + ++SK E ++ K++ S++EK
Sbjct: 2435 ETQKPVVEKSKTDELDEVRKKINADLSEVEK 2465
Score = 76.3 bits (186), Expect = 1e-10
Identities = 149/734 (20%), Positives = 298/734 (40%), Gaps = 87/734 (11%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDR----NILEAAKQALEN 2244
+++ LE K ++ ++ +FE + +++D+ N L+ + +EN
Sbjct: 14960 EKDQLEQAKSDIQRQMEEFERNMEETLKEKSRNEETLLQLLHDKDDLSNTLDEKSKEIEN 15019
Query: 2243 KVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALE---------NKVADFEATI 2091
F+ IA L + K DK+ I N+ ++ +Q E N+ +++ +
Sbjct: 15020 ITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKV 15079
Query: 2090 ATLNDELLNEKDDKK-------CIVEADK---------QALESKV-SVFEAAIATLND-- 1968
T EL + K+ KK + +AD Q LE+KV V + T D
Sbjct: 15080 -TYKTELEDSKEKKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLTDYTTQDQE 15138
Query: 1967 ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 1788
EL +E ++K I+ + N + Q L+ + E K+ + + LER+++ + + L
Sbjct: 15139 ELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKSVIMESLERRRNSLEKVQSEVLS 15198
Query: 1787 -----KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILH-EEL 1626
++ +K + Q + + + + + E ++ I +E
Sbjct: 15199 LTQEIDHLAQIKTEMQQIEIKMQIQT---------------RSVATQWETDVQIQQGQEA 15243
Query: 1625 QKEKDDKTALIKDLVAAEPGKR-TVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLA 1449
+ T ++ ++A+ K+ TV ++ L S+ + +++ +E ED +A
Sbjct: 15244 TETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMED---------VA 15294
Query: 1448 IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE 1269
MK I + E + + KS + E E + +E+ + E+ + + H++E
Sbjct: 15295 RMKTIMKMEKDQLEQAKSDIQTQMEEFE---RNMEEAMEEKSRNEEKLLQLTHDKEDLSN 15351
Query: 1268 KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
+DK + E + K + LE TI + + + ++ KQ ++R ++
Sbjct: 15352 TLDK-----KNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQER--EI 15404
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA----ERQV 921
+ ++ +E ++ ++ K E L N E K D + D D K E Q
Sbjct: 15405 QRGTDDTSNEREKYDEKVTYKTE---LEDNKEKKKPDRDSSLKLTDADSAKTDGEREAQT 15461
Query: 920 LESKVSDM-----ETT--YSTLNNELQQKM----DDNEA-----FLNER----------- 822
LE+KV D+ +TT L++E++ KM + NEA L E+
Sbjct: 15462 LETKVQDVLQLTDDTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEKCRSAEEEKSVI 15521
Query: 821 -DGLEAVKQGLEK---RVLDLEATI-HDIEMKTGKDDDYNEAEKQT------------LK 693
+ LE + LEK VL L I H ++KT + ++QT ++
Sbjct: 15522 MESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIETKMQRQTRSVATQWETDVQIQ 15581
Query: 692 KRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ E E +T K+++ + VT+L++ L E +E +D + +E +++
Sbjct: 15582 QEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQEMRDSLNKEMEDVERMK 15641
Query: 512 KCICGARDGLSTIK 471
+ +D L K
Sbjct: 15642 TMMKMEKDQLEQAK 15655
Score = 72.8 bits (177), Expect = 1e-09
Identities = 142/713 (19%), Positives = 290/713 (40%), Gaps = 73/713 (10%)
Frame = -2
Query: 2432 DKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAKQA 2253
+K+ + NDRN+L+ + L+ K+ SI D L+ K+A
Sbjct: 7109 EKELLHNDRNLLKKDVEDLQQKL---------------------MSIERDSESLKLDKEA 7147
Query: 2252 LENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE---ATIATL 2082
EN+ + A+ + +L + D+ + I + ++Q +E K A + I TL
Sbjct: 7148 FENE----KEAMKQMKTDLQIQADEIEKIKLE---THHERQRVEEKTAQIQKEREEINTL 7200
Query: 2081 NDELLNEK---DDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNIL 1911
+E+ ++ D+ + +K+A+ES S E A + + N + I RN L
Sbjct: 7201 VEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKSQTFKQNKNIEIALAEIQQKRNAL 7260
Query: 1910 EAAKQALEYKVADLEAAKTTL---NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQE 1740
E + + LE K + +ELER D ++A D +S + ++ + E
Sbjct: 7261 EKMSKEISRDRMKLEDEKKEIQLAREELERMHGDMQR-QQEAKDHLLSGITDESLLKKSE 7319
Query: 1739 DDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKR 1560
+ ++ +S+ + + + + E D K AL KD + +
Sbjct: 7320 AE---IVLQPSQVDKAKPARKTEISDSDKQPVFVQQ--MPEMDLKDALKKDFESEKLDLP 7374
Query: 1559 TVNEIVSHLESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGK 1398
V +++ + + L++ + +E D++ L++ A + K + E +K D
Sbjct: 7375 KVKDVLP--QDQQMKLEQKLIEDEMDKLKQMRAELQKEADQIEKKKQDMQNERQKLDDMA 7432
Query: 1397 SALVE------------NGEGCEAEKQG----LEKTVLERRASNLDTMDAIHEEELRKEK 1266
+ L E N + +KQ +EKT ER + +D + ++ K K
Sbjct: 7433 ARLQEERRTNERLNEEINIQKVNQQKQATAFQMEKTDFERIKTEIDQANKELADQQEKNK 7492
Query: 1265 VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND------ALQRDL-----------D 1137
+ + + E E + K V + SL+ LQ D+ +
Sbjct: 7493 KTITEMQKERETLEEMRANISKQVETITNENKSLSSRESELAKLQEDILQQQQEMDELKN 7552
Query: 1136 RVMAEKQALEKRCSD---LEAKNASLTDNQEGHEAEIER-KLEASNLTHN--DELHKEKD 975
+M E L++R SD L+ + L D + A +ER +LE T N ++ K
Sbjct: 7553 TIMMEMCQLDQRQSDIDLLQKEVDDLMDFTKTEMANVERERLEVLAQTRNIKSDMVSLKM 7612
Query: 974 DKES-------IMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 816
+KE+ + + D ++ ER++L + + + EL+ + E NE+
Sbjct: 7613 EKEACEQLRLKLNEEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKE 7672
Query: 815 LEAVKQGLEKRVL----------DLEATIHDIEMKTGKDDDYNE--AEKQTLKKRISELE 672
LE +K L+++ + D + ++ + + D +E AE + +++R+ + E
Sbjct: 7673 LEKMKISLQRKAIGFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTE 7732
Query: 671 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ K +K +++ E T+LQ+ + + +++++ ++ EL + E
Sbjct: 7733 K-------KRRKTYYTEDLFQEEKTDLQKTKEEINYDREEIYRQRTELNKEKE 7778
Score = 71.2 bits (173), Expect = 4e-09
Identities = 110/577 (19%), Positives = 245/577 (42%), Gaps = 27/577 (4%)
Frame = -2
Query: 2189 EKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALES 2010
EK ++ + +N+ ++L + + + + +L E+++ + I+ + +E
Sbjct: 13281 EKQKEEFELMQQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRME- 13339
Query: 2009 KVSVFEAAIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 1833
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 13340 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 13397
Query: 1832 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNL 1659
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 13398 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 13439
Query: 1658 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 1479
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 13440 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 13499
Query: 1478 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 1305
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 13500 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 13555
Query: 1304 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 1152
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 13556 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 13613
Query: 1151 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDE--LHKEK 978
+ ++ + +K L+ S+L + L D E++ + E S DE L +E+
Sbjct: 13614 EESMNEMTKKKSELQHERSELYKQKQQLED-MIASESKRDVDTERSRQDKEDEQILKRER 13672
Query: 977 DD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 810
++ K+ ++ + + V+ ++ + + +E S LN++ ++ +N+ L + ++
Sbjct: 13673 EEIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQ 13732
Query: 809 AVKQGLEKRVLDLE-------ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILT 651
LEK + DL+ A + + + + D E K+ K +E++ +
Sbjct: 13733 VKTNALEKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFEDIE 13792
Query: 650 DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+L+ + N ++ ++ +L S+E ++L K+
Sbjct: 13793 SVKVRLVTESN----QIDKMNSELKTRSEELENLIKK 13825
Score = 68.6 bits (166), Expect = 3e-08
Identities = 127/670 (18%), Positives = 270/670 (40%), Gaps = 78/670 (11%)
Frame = -2
Query: 2285 DRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVAD 2106
+R LE K AL+++ + E ++ E + + + + +E KQ +EN+ A+
Sbjct: 13082 ERRELEITKLALQSEQQEIEKIRQDIDREKNDLEKYRSDLEKQYEEMEICKQNIENERAE 13141
Query: 2105 FEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
E + + ++ K ++ + + Q E V + T+ DEL +++
Sbjct: 13142 LEIDLENI---IIETKSKQERLESIEVQLQEKNVQM-----GTILDELNKRQEE------ 13187
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRD 1746
L+A K + + + + DEL I+K+ +++ + + ++D
Sbjct: 13188 ----LDAIKAKTQREKEQMGHTEELEKDELIAILQKREEIVKRHMEEIQNQREELQKEKD 13243
Query: 1745 QEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE----------LQKEKDDKTAL 1596
Q +M A + +E++ L+L+ E L+K+K++ +
Sbjct: 13244 QFGNMQAELQKGQL-------------EMEMHQLMLNSERDELNGMRVNLEKQKEEFELM 13290
Query: 1595 IKDLVAAEPG---------KRTVNEIVSHLESKSRSLK----EHFLREEEDEVLERSASN 1455
++L + P K+ V E+ + L + + E R E+ + +E
Sbjct: 13291 QQNLESRRPESLLEDILKEKKRVEEMAAQLSKEQEEFRNIMSETIKRMEKIKQIEGEIKT 13350
Query: 1454 LAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT-MDAIHE--E 1284
I A EE +KE D + + E CE ++ + + L + + +D D I + +
Sbjct: 13351 KQIEMACLEELKQKELDEQKNMRE----CENQELQMRREELAKMKTEIDIERDEIQKLRK 13406
Query: 1283 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA----------LQRDL-- 1140
+ KEK + + + + E EK E ++ I SL + LQ L
Sbjct: 13407 QYEKEKCELEQIKPDLQKREPEKIDAEVQHDEIHGGIDSLKEEREEIEKMKADLQNKLRE 13466
Query: 1139 -----DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEA------------- 1017
D + EK LEK+ +++E DN + E K+EA
Sbjct: 13467 AENMRDIMKREKDELEKKEAEIEQMAVETEDNDSDKNLQDEMMKIEAILKVTKKQKNYLE 13526
Query: 1016 ---SNLTHND---------------ELHKE-KDDKESIMNDLDHVKAERQVLESKVSDME 894
NLT EL+K+ K+ +E M+ ++ +AER+ +E + +M
Sbjct: 13527 QMNENLTREKTELETNCQMLEREKTELNKKVKETEEFHMSKMEEREAERKTIERVMDEMA 13586
Query: 893 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY-- 720
+ + E ++ ++ E +R LE + K+ +L+ ++ + + +D
Sbjct: 13587 EEHEKIKKEREELVNMEEEIKKQRRVLEESMNEMTKKKSELQHERSELYKQKQQLEDMIA 13646
Query: 719 NEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKR 540
+E+++ +R + +E IL + +++ + L E +++ + ++EK+ +EK
Sbjct: 13647 SESKRDVDTERSRQDKEDEQILKREREEIADMKDQLLKEKEDVETTKERINREKEHIEKM 13706
Query: 539 VLELTSKLEK 510
+L + E+
Sbjct: 13707 QSQLNDQKEE 13716
Score = 66.2 bits (160), Expect = 1e-07
Identities = 120/590 (20%), Positives = 242/590 (41%), Gaps = 46/590 (7%)
Frame = -2
Query: 2159 DRNIVEADKQALENKVADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIA 1980
+R + A+ Q + ++ T+ + DE+ + ++ + + L K ++ E
Sbjct: 8354 ERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKNM-EKTYE 8412
Query: 1979 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL----------NDELER 1830
NDE+ EK I + + +L + LE ADLE K + N+ LER
Sbjct: 8413 QQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLER 8469
Query: 1829 KKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKI 1671
+K D II+ +A +R ++ A A +RD E+ M + +
Sbjct: 8470 EKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQEASKNQMV 8528
Query: 1670 --------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH---LESK 1524
+ L+ ++L EL+K K D + DL ++T +EI+ H +SK
Sbjct: 8529 ELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKHEKDTDSK 8582
Query: 1523 SRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENGEGCEAEK 1356
+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 8583 TRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM----------- 8630
Query: 1355 QGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEKQGPEKTV 1194
K V+ +R D M+ I EE+ +E+ + L N + + + +
Sbjct: 8631 ----KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLERT 8682
Query: 1193 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEAS 1014
+LE ++ D++R++ E + + +L+ E+ER++E S
Sbjct: 8683 ANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EMERRMEKS 8723
Query: 1013 NLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTLNNELQQK 855
+ DE K + + + D+ ++ L ++ ++E + L + Q++
Sbjct: 8724 KV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELAEKQQEQ 8782
Query: 854 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 675
E ER+ LE +K + + D+E +E K++ + Q K+ + +
Sbjct: 8783 ESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSV 8842
Query: 674 EEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 528
E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8843 TE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8888
Score = 65.9 bits (159), Expect = 2e-07
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = -2
Query: 1565 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 1389
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 1388 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 1209
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 1208 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 1029
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 1028 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 900
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 899 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 723
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 722 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 564
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 563 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 399
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 398 RKTSPLDITKT-----CDAVDISEDST 333
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.9 bits (159), Expect = 2e-07
Identities = 125/657 (19%), Positives = 260/657 (39%), Gaps = 68/657 (10%)
Frame = -2
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
I ++ +E++K L + D E A L + DK+ ++ + ++E +K +
Sbjct: 8418 IQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKADVIKI 8477
Query: 2114 VADFEATIATLNDELLNE------KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNE 1953
+ + E+ E E +D ++ + + + ++E + + L ++
Sbjct: 8478 IENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQEASKNQMVELKRQIDKL 8537
Query: 1952 KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND---------------ELERKKDD 1818
+ K ++ + L+ K L+ ++ DLE ++ + E++R+KDD
Sbjct: 8538 IELKADLLQQQTELKKTKADLKQQMDDLEKTRSEILKHEKDTDSKTRELELIEIQRQKDD 8597
Query: 1817 NNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLE-- 1656
I+K L+KR + L+++ ++D + M +I +
Sbjct: 8598 LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRE 8657
Query: 1655 -VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSRSLK--- 1509
+ IL +Q + D +TA ++D +A +R V E+V + R+LK
Sbjct: 8658 RQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVRNLKGEM 8716
Query: 1508 EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLEKTVL 1332
E + + + E+ E+ I + I++ ++R+ G +E + E + + +
Sbjct: 8717 ERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAELA 8776
Query: 1331 ERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT-VLDLE 1182
E++ + +H+E E+ +EK D E E +++ E T + +
Sbjct: 8777 EKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYK 8836
Query: 1181 PTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1011
+ S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +K E
Sbjct: 8837 EELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-KKGEQLL 8895
Query: 1010 LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 831
DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8896 EKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDLFRSELQ 8955
Query: 830 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------------ 687
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8956 RQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKIRFDIAN 9012
Query: 686 ----ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 528
I + + IL D + +D + E +L E D+E+ VLE+
Sbjct: 9013 ARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLVLEV 9065
Score = 64.3 bits (155), Expect = 5e-07
Identities = 123/636 (19%), Positives = 256/636 (40%), Gaps = 49/636 (7%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
+E AK +++ + E + DE+ E + K I + ++ DK ALE + D
Sbjct: 453 IEQAKVDIQSHMISMEGRV----DEIKRETERLKHIKTE---MQRDKDALEKQKDDTRKA 505
Query: 2093 IATLND---ELLNEKDDKKCIVEADKQALESKVSVFEAAIATLND----ELLNEKDDKKC 1935
E++ E+ + + ++ ++ LE+ A + +ND ++L EK++
Sbjct: 506 KEEAERKRYEIVTEELEHRARLQRERDELEN----IRAEMQRVNDVEKAKILKEKEES-- 559
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAP 1755
+ R ++ E A+++A K LN E + I +RI A
Sbjct: 560 -IRIREEARQERETTELVNAEIKAEKERLNQRQEEMLRERQEI------ERIKHETLRAK 612
Query: 1754 QRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAA 1575
+ + E+ + I + ++E + EE+QK K+ +L
Sbjct: 613 E-EIENSQDVTIREYEKMEKMKAEIQGQIEDIEKKV----EEIQKTKEQMEEAKVELEEE 667
Query: 1574 EPGKRTVNEIVSHLESKSRSLKEHFLREEED-------------EVLERSASNLAIMKAI 1434
++VS ++ L+ LR +E+ E+ ++ L ++ +
Sbjct: 668 REDLERKRDLVSREIEQAEFLRNEILRVKEEMESRWRETETEEVELRAKTQHELERLEKL 727
Query: 1433 REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKS 1254
REE R +K+ + + +E L K L++ ++ + ++ + K +
Sbjct: 728 REETERSQKNIEESKIE---------LMLWKESLDKLKGEMEEDKHVVIMQMNEAKAKEE 778
Query: 1253 ALTENGEGCEAEKQ----GPEKTVLDLEPTIPSLNDALQR------DLDRVMAEKQALEK 1104
LT E E E+ EK +L+ I + + LQR D RV+ K+ E
Sbjct: 779 QLTMVIEQLEIERGEITISREKVKEELDE-INRMRNELQRQHAEMEDWFRVV-NKEKEEA 836
Query: 1103 RCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDELHKEKDDKESIMNDLDHVKAE- 930
+ L A + ++ E+E R ++ L DE+ K+ ++ E I ++ + E
Sbjct: 837 NLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAEELEQINKEIQRARQEL 896
Query: 929 -----------RQVLESKVSDMETTYSTLNNELQQKMDDNEAFL---NERDGLEAVKQGL 792
+++LE + + L+ K D ++ +ER LE ++ +
Sbjct: 897 EKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLFEMDSERKELEQMRFQV 956
Query: 791 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL---EEAISILTDKAKKLLKDI 621
E DLE +++ + + +K+ L+K S+L E+++ + A++ +
Sbjct: 957 ENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTESMNRSRELARQDREKA 1016
Query: 620 NIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 513
+ + E+ E +ED+NK +E + E+ + L +E
Sbjct: 1017 ELLIVEIQEQREDVNKRLEETKQREEALRLLRKDME 1052
Score = 63.5 bits (153), Expect = 8e-07
Identities = 123/686 (17%), Positives = 275/686 (40%), Gaps = 44/686 (6%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++DK V+ N +A ++ L + E I RN L+
Sbjct: 760 EEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEINRMRNELQRQH 819
Query: 2258 QALEN--KVGDFEAAIATLNDELLNEKD---DKKCIVNDRNIVEADKQALENK--VADFE 2100
+E+ +V + E A L ++E + K+ +++ E +ALE + +
Sbjct: 820 AEMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKA 879
Query: 2099 ATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAA---IATLNDELL-NEKDDKKCI 1932
+ +N E+ + + + + +K++L+ + + + + ELL N+ D KC+
Sbjct: 880 EELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCL 939
Query: 1931 V---NDRNILEAAKQALEYKVADLEAAKTTL-------NDELERKKDDNNAIIKKALDKR 1782
++R LE + +E + DLE + + + +++R+K++ I + +
Sbjct: 940 FEMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDT 999
Query: 1781 ISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKT 1602
S ++ R + LI + E + +L ++++ E++D
Sbjct: 1000 ESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENERED-- 1057
Query: 1601 ALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE 1422
L K V GK T E+ + ++ + E+ + ER N + IR+ E
Sbjct: 1058 -LEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKME 1116
Query: 1421 LRKEKDGK--SALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELR-KEKVDKSA 1251
K + G+ VE + E +E LE +NL+ M A + LR KE ++
Sbjct: 1117 AMKREMGEIEDMKVELTKQKENIDMKMEHARLEM--TNLEMMKA---DLLRQKEDIENQM 1171
Query: 1250 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 1071
L E + E E +L + + + + +++++ K ++K+ +LE +
Sbjct: 1172 LAAKSERQQMEVMRTE--ILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 1070 LTDNQEGHEAEIERKLEASNLTHNDELH---KEKDDKESIMNDLDHVKAERQVLESKVSD 900
T + G ++R++E + + ++K++ E + ++ K + + +
Sbjct: 1230 -TKREIGEMELMKREMEGKKKELDQRMKLTMRKKEEMERLKMEIQRAKDDMEFKRVETER 1288
Query: 899 METTYSTLNNELQQKMDDNEAFLNERD-----------------GLEAVKQGLEKRVLDL 771
+ + E+Q+ ++ E + ERD +EA ++ + K
Sbjct: 1289 QKYEMEQVKAEIQRAREEFELRVEERDLEEEKEQMNLTIINLIQQIEATREMVHKTKFQF 1348
Query: 770 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
E + +M T ++ N AE Q L I + E + L + ++ + + E+ L
Sbjct: 1349 ENRMAGSQMGTADQEEMN-AEMQRLILEIEHIREMLRGLKGEVEQNKEIMKRDREEIRLL 1407
Query: 590 QEDLNKESKEKQDLEKRVLELTSKLE 513
+ ++ + +E + E++++ +LE
Sbjct: 1408 KIEVQRRRREIEYREEKIMREQDELE 1433
Score = 61.2 bits (147), Expect = 4e-06
Identities = 115/678 (16%), Positives = 265/678 (39%), Gaps = 38/678 (5%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
++ + + + +E K ++ ++ D E + + +R LE +
Sbjct: 616 ENSQDVTIREYEKMEKMKAEIQGQIEDIEKKVEEIQKTKEQMEEAKVELEEEREDLERKR 675
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLN 2079
+ ++ E L +E+L K+ E + + E + + E T +
Sbjct: 676 DLVSREIEQAEF----LRNEILRVKE------------EMESRWRETETEEVELRAKTQH 719
Query: 2078 D----ELLNEKDDKKCIVEADKQALESKVSV--FEAAIATLNDELLNEKDDKKCIVNDRN 1917
+ E L E+ ++ + K ESK+ + ++ ++ L E+ ++DK ++ N
Sbjct: 720 ELERLEKLREETER-----SQKNIEESKIELMLWKESLDKLKGEM---EEDKHVVIMQMN 771
Query: 1916 ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQED 1737
+A ++ L + LE + + E+ K++ + I ++ ++L+ Q
Sbjct: 772 EAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEI-----NRMRNELQR------QHA 820
Query: 1736 DMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDK-TALIKDLVAAEPGKR 1560
+M V E+ + EE +K + + T ++ +
Sbjct: 821 EMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRRYEMITEALEQRDEIQKKAE 880
Query: 1559 TVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALV 1386
+ +I ++ + L++ +F +E ++LE + ++ +R E L+ + D L
Sbjct: 881 ELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFVEQVRSELLKNKADQDKCLF 940
Query: 1385 E-NGEGCEAEKQGL----EKTVLERRASNLDTMDAIHEEELRKEK-----------VDKS 1254
E + E E E+ EK LE+R + D +++++K +D
Sbjct: 941 EMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQVQRQKEELEKIKSQLVIDTE 1000
Query: 1253 ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMA----------EKQALEK 1104
++ + E +++ E +++++ +N L+ R A E++ LEK
Sbjct: 1001 SMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQREEALRLLRKDMENEREDLEK 1060
Query: 1103 -RCSDLEAKNASLTDNQEGHE--AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA 933
R L K+ +E + AEIER + + +E K +KE ++ ++ +K
Sbjct: 1061 IRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEEREKINHEKEEMIRKMEAMKR 1120
Query: 932 ERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHD 753
E ++ DM+ + + KM+ E LE +K L ++ D+E +
Sbjct: 1121 EM----GEIEDMKVELTKQKENIDMKMEHARL---EMTNLEMMKADLLRQKEDIENQM-- 1171
Query: 752 IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 573
+ + E + + K+ ++E + + + +K+ + + EL+E + K
Sbjct: 1172 --LAAKSERQQMEVMRTEILKQKEDVERKMELAKAEMEKMQHVKDEIQKQRKELEERMQK 1229
Query: 572 ESKEKQDLEKRVLELTSK 519
+E ++E E+ K
Sbjct: 1230 TKREIGEMELMKREMEGK 1247
>ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121915630|gb|EAY20417.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 4263
Score = 116 bits (291), Expect = 8e-23
Identities = 166/694 (23%), Positives = 281/694 (40%), Gaps = 50/694 (7%)
Frame = -2
Query: 2441 EKDDKKYVVNDR-NILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEA 2265
EKDDK N + + L + L K + + I + + LE
Sbjct: 2135 EKDDKINEFNAKLSTLSSSSDELTTKFINAQNEINQLTKQNNEKDNLISQLNQKISDLEN 2194
Query: 2264 AKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIAT 2085
AK LEN+ L E N + +K ++ + +E +KQ LE + + E A
Sbjct: 2195 AKSQLENEKSQ-------LIQEKTNLEQEKAQLLEQKKNLEEEKQKLETEKTNLEQEKAK 2247
Query: 2084 LNDELLNEKDDK------KCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVND 1923
L +E N + +K K +E +K L + + E A L +E N + +K ++ +
Sbjct: 2248 LIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEE 2307
Query: 1922 RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQ 1743
+ LE K + +LE K L +E + + +I++ + K + +
Sbjct: 2308 KTNLEQEKAKPIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNL 2367
Query: 1742 EDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGK 1563
E + LI + +NLE L EE + +K LI++ E K
Sbjct: 2368 EQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEK 2427
Query: 1562 RTVNEIVSHLE-SKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALV 1386
+ E ++LE KS+ L + EEE + LE + L K E+E + + K L
Sbjct: 2428 AKLIEEKTNLEQEKSQLLDQKKNLEEEKQRLETEKAKLIEDKTNLEQEKAQLLEQKKNLE 2487
Query: 1385 ENGEGCEAEKQGLEKTVLERRAS--------NLDTMD-AIHEEELRK---EKVDKSALTE 1242
E E EK +KT+ E+ N+ T D ++ E + D+S +
Sbjct: 2488 EEKAKLEEEKAQAQKTIEEKDQEIEDLTSQINVKTKDLSLLESDFNNMSFTNADQSTMIS 2547
Query: 1241 NGEGCEAEKQGPEKTVLDLEPTIPSL---NDALQRDLDRV---MAEKQALEKRCSDLEAK 1080
N E E K + DL+ + + D LQ D++ + EK+ ++ S LE K
Sbjct: 2548 N---YEKELSDKNKEINDLQNQLKQMTQNRDELQSKSDKLNEEIEEKKNIQNLESSLEQK 2604
Query: 1079 N-------ASLTDNQEGHEAEIERKL-EASNLTHNDELHKEKDDKESIMNDLDHVKAERQ 924
N L Q A++++K E NLT K+K ++ N+ + ++
Sbjct: 2605 NKENEDLKQQLNKTQGELSAQLQQKTQELENLTKEFNDLKQKSEQTIAQNNEEIANLKKN 2664
Query: 923 VLE--SKVSD-METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----- 768
V E K+S +E + L +L K ++N + N E L+K V D E
Sbjct: 2665 VAERDKKISQLLENEVNELKKKLSDKENENTSLKNTISERENEINNLKKNVSDKENEINQ 2724
Query: 767 ----ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV 600
T+ + E+ KD++ A KQ + ++ +LEE D L K N L ++
Sbjct: 2725 LKNNLTMRETELNKMKDEEVKNA-KQIIAQKDKDLEELNGKFNDTNNNLSK-ANDELKQL 2782
Query: 599 TELQEDLNKESKEKQD----LEKRVLELTSKLEK 510
E E LNK+ ++ + E + +LTS L+K
Sbjct: 2783 KEQIESLNKQIEQMKCSNNLKESEIKQLTSNLQK 2816
Score = 92.4 bits (228), Expect = 2e-15
Identities = 148/732 (20%), Positives = 304/732 (41%), Gaps = 42/732 (5%)
Frame = -2
Query: 2411 DRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDR-NILEAAKQALENKVG 2235
D N+LE Q E ++A+ + I ++N++ N +++ KQ + K
Sbjct: 1390 DINVLEGNCQVYEQEIAEKDKQIEQMTNDIKSLE----EVINEQSNTIDSLKQDVATKEE 1445
Query: 2234 DFEAAIATL--NDELLN------EKDDKKCIVNDRNIVEADKQA----------LENKVA 2109
+ + T+ N+E++ E+ D + I ++ +E KQ L++++
Sbjct: 1446 EIKQLKQTVSENEEVIKQLQTDIEQKDAE-IQKNKEEIEQHKQTISQRDETIKQLQSEIE 1504
Query: 2108 DFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDD----K 1941
+ TIA N+E+ K+ E KQ L++++ + +A + E+ K++ K
Sbjct: 1505 QHKQTIADKNNEIEQLKNTISEREETIKQ-LQNEIEQHKQTMAERDAEIQKNKEEIEQQK 1563
Query: 1940 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK-----KALDKRIS 1776
+ I N+ N +E K+ + + A++E K T+ + E K N I + D I
Sbjct: 1564 QTISNNNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRDAEIE 1623
Query: 1775 DLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTAL 1596
LK QRDQ + N E+ E+L++ + +
Sbjct: 1624 QLKQTVQQRDQTIAEKEDLIKQLQSEIEQHKQTISDKNNEI------EQLKQTVNARDEA 1677
Query: 1595 IKDLVAA-EPGKRTVNEIVSHLESKSRSLKEHFLR-EEEDEVLERSASNLAIMKAI---R 1431
IK L + E K+T+ E + ++ +++ + DE +++ + + K R
Sbjct: 1678 IKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDETIKQLQNEIEQHKQTISQR 1737
Query: 1430 EEELRKEKDGKSALVENGEGCEAEKQGLEKTV---LERRASNLDTMDAI---HEEELRKE 1269
+ E+ + K V+ + AEK+ L K + +E+ + DA ++EE+ ++
Sbjct: 1738 DAEIEQLKQ----TVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQ 1793
Query: 1268 KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 1089
K S E+ + ++E + ++T+ D E I + + + ++ +E+ +
Sbjct: 1794 KQTISQRDESIKQMQSEIEQNKQTIADREKEIEQHKQTIAERDNSIKQLQEEIEQHKQTI 1853
Query: 1088 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESK 909
++A + N+E EI++K EA N N E ++K + +L+ A + L +K
Sbjct: 1854 AERDAEIQKNKE----EIQQKNEAINALTN-----EGEEKRLKILELE---ANNENLINK 1901
Query: 908 VSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG-- 735
V ++ + S LN L+ + VKQ + + DL IH++E+K+
Sbjct: 1902 VKELNDSVSDLN-------------LSTENQNSVVKQ-MTDEIKDLNKQIHELEVKSENQ 1947
Query: 734 -KDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEK 558
K + + E Q+L ++ EE I L ++ + L N + LQE + ++ K
Sbjct: 1948 QKQIEEKDKEIQSLTNTKAQNEELIKKLQEEVENLTNTKNQNEETIKNLQEQVQSLTETK 2007
Query: 557 QDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLD 378
E + + +++ + TIK + + E+ ++ + L
Sbjct: 2008 NQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKATNEETIKKLQGEVQSLT 2067
Query: 377 ITKTCDAVDISE 342
TK + I +
Sbjct: 2068 ETKATNEEQIKK 2079
Score = 83.6 bits (205), Expect = 8e-13
Identities = 138/669 (20%), Positives = 286/669 (42%), Gaps = 29/669 (4%)
Frame = -2
Query: 2438 KDDKKYVVNDRNILEAGKQALENKVADFETAIATXXXXXXXXXXXXKSIVNDRNILEAAK 2259
+ K+ + N+ N +E K+ + + A+ E T SI +N +E K
Sbjct: 1560 EQQKQTISNNNNEIEQLKKTISERDAEIEQLKKTIAERDE-------SIKQLQNEIEQHK 1612
Query: 2258 QALENKVGDFEAAIATLN--DELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIAT 2085
Q + + + E T+ D+ + EK+D I ++ +E KQ + +K + E T
Sbjct: 1613 QTISQRDAEIEQLKQTVQQRDQTIAEKED--LIKQLQSEIEQHKQTISDKNNEIEQLKQT 1670
Query: 2084 LN--DELLNE-----KDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVN 1926
+N DE + + + K+ I E D + ++K + + + ++++D+ I
Sbjct: 1671 VNARDEAIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQ------QKQTISQRDET--IKQ 1722
Query: 1925 DRNILEAAKQALEYKVADLEAAKTTL--NDELERKKDDNNAIIKKALDKRISDLKADAPQ 1752
+N +E KQ + + A++E K T+ +D+ +K+D + K L I K +
Sbjct: 1723 LQNEIEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKED----LIKQLQSEIEQHKQTIAE 1778
Query: 1751 RDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLVAAE 1572
RD E N + +S + +I + E+++ K K++ E
Sbjct: 1779 RDAEIQKNK---------EEIEQQKQTISQRDESIKQMQSEIEQNKQTIADREKEI---E 1826
Query: 1571 PGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSA 1392
K+T+ E + ++ +++H + + ER A I K +EE++++ + +A
Sbjct: 1827 QHKQTIAERDNSIKQLQEEIEQH-----KQTIAERDAE---IQK--NKEEIQQKNEAINA 1876
Query: 1391 LVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ 1212
L GE EK+ +LE A+N + ++ + +EL D + TEN
Sbjct: 1877 LTNEGE----EKR---LKILELEANNENLINKV--KELNDSVSDLNLSTEN--------- 1918
Query: 1211 GPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 1032
V + I LN + + + + + +K+ + + + SLT+ + +E E+
Sbjct: 1919 -QNSVVKQMTDEIKDLN----KQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNE-ELI 1972
Query: 1031 RKL--EASNLTHNDELHKE--KDDKESIMN-------DLDHVKAERQVLESKVSDMETTY 885
+KL E NLT+ ++E K+ +E + + + D +K +++ ++S +
Sbjct: 1973 KKLQEEVENLTNTKNQNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENE 2032
Query: 884 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEK 705
T+ N +Q E + ++ + QG + + + +AT + K ++ K
Sbjct: 2033 ETIKNLQEQVQSLTETKATNEETIKKL-QGEVQSLTETKATNEEQIKKQQEEIQSLSNTK 2091
Query: 704 QTLKKRISELEEAISILT-------DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 546
++ I +L+E I LT ++ KKL ++I + E + +N+ + + L
Sbjct: 2092 NENEELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLS 2151
Query: 545 KRVLELTSK 519
ELT+K
Sbjct: 2152 SSSDELTTK 2160
Score = 78.2 bits (191), Expect = 3e-11
Identities = 118/652 (18%), Positives = 263/652 (40%), Gaps = 58/652 (8%)
Frame = -2
Query: 2291 VNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKV 2112
+ L+ + L ++ D+E +++L + ++ + I N NI++A L+
Sbjct: 1258 IESTEALQKKSRELYRQIRDYEQRLSSLGLTVEQIREMEMTIKNQANIIKAKDDDLKQ-- 1315
Query: 2111 ADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCI 1932
E+L ++++ A+ ++ + + I+ L E+L EK DK+
Sbjct: 1316 ----------TKEILEYREEQIEKFIAESVSIRDAIETLKQRISEL--EMLLEKKDKENN 1363
Query: 1931 VNDRNILEAAKQALEYKVADLEAAKTTLN-----------------DELERKKDDNNAI- 1806
I E +Q LE L+ A+ +N ++E+ +D ++
Sbjct: 1364 DKIAEIQEENRQTLEQLAKQLQEAEEDINVLEGNCQVYEQEIAEKDKQIEQMTNDIKSLE 1423
Query: 1805 -IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE 1629
+ I LK D +++E +++ L+ +I E
Sbjct: 1424 EVINEQSNTIDSLKQDVATKEEE---------IKQLKQTVSENEEVIKQLQTDIEQKDAE 1474
Query: 1628 LQKEKDD----------KTALIKDLVA-AEPGKRTVNEIVSHLESKSRSLKEHFLREEED 1482
+QK K++ + IK L + E K+T+ + + +E ++ E REE
Sbjct: 1475 IQKNKEEIEQHKQTISQRDETIKQLQSEIEQHKQTIADKNNEIEQLKNTISE---REETI 1531
Query: 1481 EVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRA--SNLD 1308
+ L+ A R+ E++K K+ + E + L+KT+ ER A L
Sbjct: 1532 KQLQNEIEQHKQTMAERDAEIQKNKEEIEQQKQTISNNNNEIEQLKKTISERDAEIEQLK 1591
Query: 1307 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 1128
A +E +++ + + + +AE + ++TV + TI D +++ +
Sbjct: 1592 KTIAERDESIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQRDQTIAEKEDLIKQLQSEIE 1651
Query: 1127 AEKQALEKRCSDLEAKNASLTDNQEG---HEAEIER------KLEASNLTHNDELHKEKD 975
KQ + + +++E ++ E ++EIE+ + +A + +E+ ++K
Sbjct: 1652 QHKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQ 1711
Query: 974 D----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 807
E+I + ++ +Q + + +++E T+ Q + + + +E
Sbjct: 1712 TISQRDETIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQ 1771
Query: 806 VKQGLEKRVLDLEATIHDIEMK----TGKDDDYN------EAEKQTLKKRISELE---EA 666
KQ + +R +++ +IE + + +D+ E KQT+ R E+E +
Sbjct: 1772 HKQTIAERDAEIQKNKEEIEQQKQTISQRDESIKQMQSEIEQNKQTIADREKEIEQHKQT 1831
Query: 665 ISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 510
I+ + K+L ++I + E ++ K +E Q + + LT++ E+
Sbjct: 1832 IAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKEEIQQKNEAINALTNEGEE 1883
Score = 77.0 bits (188), Expect = 7e-11
Identities = 140/634 (22%), Positives = 261/634 (41%), Gaps = 44/634 (6%)
Frame = -2
Query: 2279 NILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFE 2100
N L+ +QA++ D + + + EL + K + N+ N + KQ EN++A
Sbjct: 2886 NELKKKQQAID----DLQNNLKQKDAELTDTKQKLEAKTNEFNDL---KQKAENEIASLR 2938
Query: 2099 ATIATLNDELLN-EKDDKKCIVEADKQALES-KVSVFEAAIATLNDELLNEKDDKKCIVN 1926
I L +L N K+ + E+D Q E+ K+ V A IA + L +E ++ N
Sbjct: 2939 KEIEQLKAKLANTSKELEASKSESDLQKKENDKLKVNLAKIAEMYKTLKSESENNSAKSN 2998
Query: 1925 DR-NILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 1749
D+ ++ Q LE +V ++ A L +E + +K+ + KK L+ S
Sbjct: 2999 DKIKQMQEKIQNLEIQVEKMKLANENLTNENKLQKETIEMLNKKLLESNKS--------- 3049
Query: 1748 DQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEE---LQKEK---DDKTALIKD 1587
+ A I ++ L + L ++ L+KEK D K + D
Sbjct: 3050 -----LTASIKEYETLKRENNLQKDQITKLTSQVQKLTQDFTQLKKEKAEVDSKLNELLD 3104
Query: 1586 LVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE----EEDEVLERSASNLAIMKAIREEEL 1419
L+A + ++ + L+S+++ L E + + EE E L +S +N I E
Sbjct: 3105 LLAQK------DKEIERLKSENQKLNELYQQITKDLEEKEFLIQSQNNRCIDLLNLTE-- 3156
Query: 1418 RKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL---DTMDAIHEEELRKEKVDKSA- 1251
+K K+ ++ + N ++ L K+ +E R + + D I E + D+ +
Sbjct: 3157 KKNKEIETLQISN----DSLNNSLTKSQMELREKSTLLENAKDKITESNRKLALFDRLSA 3212
Query: 1250 ------LTENGEGCE--------AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQA 1113
LT +G G + + K + E TI L +L+ + V A K+
Sbjct: 3213 NSSELNLTSSGRGIKKSSSMNLSTDMDSKNKIINQQEQTIIGLEQSLKVSKNEVDATKRE 3272
Query: 1112 LEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKA 933
L+K+ + + + +E A++E KL++ ND KD + + D
Sbjct: 3273 LQKQLQNNKELQNQIKMTKEQF-AKLEAKLQSVVKKLND-----KDQRIDSLMSSDPNNK 3326
Query: 932 ERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHD 753
+ L ++SD+ L + +N++ +D LE+ K K A +
Sbjct: 3327 QTNQLNKQISDLNLENEKLKTRVDIITRENQSL---KDDLESQKSQKSKLDESCNALKTE 3383
Query: 752 IEMKTGKDDDYNEAEKQTLK------KRISELEEAISILTDKAKKLLKDINIWLSEVTEL 591
+ K D Y E K+ ++ K+ISEL+ + D+ +K + E+TEL
Sbjct: 3384 LINKKSIMDQYKEKLKELMEQINLKNKQISELKAEFNGSDDEDRKSYVKVIEQEGEITEL 3443
Query: 590 QEDLNKESK-------EKQDLEKRVLELTSKLEK 510
+ ++++ K + DLEK + E + +K
Sbjct: 3444 KVIIDRQKKFVGQQKMKIADLEKNLKESNDEAQK 3477
Score = 71.6 bits (174), Expect = 3e-09
Identities = 130/670 (19%), Positives = 262/670 (39%), Gaps = 110/670 (16%)
Frame = -2
Query: 2210 LNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATLNDELLN-------EKDD 2052
L ++ + ++K+ ++ +N D L K T+ ND L N E +
Sbjct: 3126 LYQQITKDLEEKEFLIQSQNNRCIDLLNLTEKKNKEIETLQISNDSLNNSLTKSQMELRE 3185
Query: 2051 KKCIVEADKQALES---KVSVFEAAIATLND----------------ELLNEKDDKKCIV 1929
K ++E K + K+++F+ A ++ L + D K I+
Sbjct: 3186 KSTLLENAKDKITESNRKLALFDRLSANSSELNLTSSGRGIKKSSSMNLSTDMDSKNKII 3245
Query: 1928 NDRN-ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNN-----------------AII 1803
N + + +Q+L+ +++A K L +L+ K+ N +++
Sbjct: 3246 NQQEQTIIGLEQSLKVSKNEVDATKRELQKQLQNNKELQNQIKMTKEQFAKLEAKLQSVV 3305
Query: 1802 KKALDK--RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVS--NLEVNILILH 1635
KK DK RI L + P Q + +N I I++ N + +
Sbjct: 3306 KKLNDKDQRIDSLMSSDPNNKQTNQLNKQISDLNLENEKLKTRVDIITRENQSLKDDLES 3365
Query: 1634 EELQKEKDD------KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE----------- 1506
++ QK K D KT LI + K + E++ + K++ + E
Sbjct: 3366 QKSQKSKLDESCNALKTELINKKSIMDQYKEKLKELMEQINLKNKQISELKAEFNGSDDE 3425
Query: 1505 ---HFLR--EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEK 1341
+++ E+E E+ E K + ++++ K D + L E+ + + + L+
Sbjct: 3426 DRKSYVKVIEQEGEITELKVIIDRQKKFVGQQKM-KIADLEKNLKESNDEAQKMTKNLQT 3484
Query: 1340 TV--LERRASNLD---------------TMDAIHEE-ELRKEKVDKSALTENGEGCEAEK 1215
T+ LE R NL+ T++ +++E E K K+D + + + K
Sbjct: 3485 TIYELEDRCQNLNQTIEMKNFRLRENEKTIEDLNKEIEFLKGKIDILSREISMYSDNSSK 3544
Query: 1214 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALE---KRCSDLEAKNASLTDNQEGHE 1044
++ L+ T+ ++ L D + +LE K +++ KN+ + H
Sbjct: 3545 DNLISKIVSLQKTVSEKDEQLN---DAKINSNNSLEIEDKMQQEIDQKNSRI------HH 3595
Query: 1043 AEIERKLEASNLTHND---------ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMET 891
E + ++ + +H + +L K ++ ND ++ E L+SKVS +E
Sbjct: 3596 LENQMRVLLNKASHENAKEESKVKIDLKKANVKLSNLENDFSSLQEENAALKSKVSKLEL 3655
Query: 890 TYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA 711
+E+ N +NE I +++ K K ++
Sbjct: 3656 VIKEKQSEINIMAQKNNNDINE---------------------ISELKSKLRKQNEDFTQ 3694
Query: 710 EKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQED-------LNKESKE 561
EK + +K+ SE+++ + L K +L +I I S++ +LQ+D L KES++
Sbjct: 3695 EKSSAEKQRSEIDQLTNDLKAKNNELDDSKSEIRILKSKINQLQQDFDAKNHSLQKESEK 3754
Query: 560 KQDLEKRVLE 531
LE+++ E
Sbjct: 3755 LSQLEEKMKE 3764
>ref|XP_001582797.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121917034|gb|EAY21811.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 1553
Score = 116 bits (291), Expect = 8e-23
Identities = 155/698 (22%), Positives = 285/698 (40%), Gaps = 57/698 (8%)
Frame = -2
Query: 2441 EKDDKKYVVNDRNI-----------LEAGKQALENKVADFETAIATXXXXXXXXXXXXKS 2295
E ++ VND+N L+ KQ L+ D I T +
Sbjct: 456 ETENLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVKEDLTNTITTKDDEIKDLKKQNED 515
Query: 2294 IVNDRNILEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENK 2115
+ N N LE K+ L N V + ++ + L ++ ++ K +D N ++ Q LE+K
Sbjct: 516 LQNQNNDLEKQKEDLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLEDK 575
Query: 2114 VADFEATIATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKC 1935
V D E I DE+ E + V+ L++ + LN L+ +
Sbjct: 576 VTDLEGKI----DEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDS 631
Query: 1934 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDN--NAIIKKALDKRISDLKAD 1761
+ +D N L++ K +LE +DLE L + LE +K+ + N+ +++ D +
Sbjct: 632 LNSDVNDLKSQKDSLEKDKSDLEKKVKELEEALEDEKNSSLLNSSNFNEESQKLMDKINE 691
Query: 1760 APQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKDLV 1581
++++E + N K + N + N+ ++ L + D+ +DL
Sbjct: 692 LTKQNREKNQNI----------------KKLENEKANLQQNNDNLNQRLDNVKKQYEDLQ 735
Query: 1580 AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE--EELRKEK 1407
A++ S L K L E F +E + E S N A + I++ +L +
Sbjct: 736 ASK----------SELVGKYNDLVEKFNKERQTNN-ELSQQNQAQKQQIQQLMNDLASLR 784
Query: 1406 DGKSALVENGEGCEA----EKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTEN 1239
DGKS +V+ A E+Q KT + + DA+ + E +K ++ L +
Sbjct: 785 DGKSDIVQKYNDLVAKFNDERQEAAKTKSDLQNQIQQLKDALAKAE-SNQKETQNKLDIS 843
Query: 1238 GEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN 1059
E EK + LE + +L LQ+ + + LE + + NA L+D
Sbjct: 844 NSDLEKEKDKSKS----LEEELAALKSKLQQVQEEKANLESDLENERQNNSSSNAELSDK 899
Query: 1058 QEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYST 879
+ E + N ND L +++ + + + +DLD++ Q LES+++DM+
Sbjct: 900 LSKLQQENRDLVNQINQLQND-LKQKESEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDE 958
Query: 878 LNNELQQKMDDNEA--------------FLNERDGLEAVKQGLEKRVLDLE-------AT 762
L+ +L +DDNE NE+D L E LDL
Sbjct: 959 LSKKLSNLVDDNERKDKLIDDLNSQLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLKV 1018
Query: 761 IHDIEMKTGKDDDYNEA----------EKQTLKKRISELEEAISIL-------TDKAKKL 633
I D++ ++ D N + E LK+++++LE+ +S L ++ KL
Sbjct: 1019 IEDLQRSLSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQVSNLKQENETQNEEISKL 1078
Query: 632 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 519
D+ + ++++ K KE Q L++ + +L ++
Sbjct: 1079 NNDLREAADYIEKIKQQYLKLKKENQALKEEISKLKAE 1116
Score = 109 bits (273), Expect = 1e-20
Identities = 135/613 (22%), Positives = 264/613 (43%), Gaps = 30/613 (4%)
Frame = -2
Query: 2258 QALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQ-----ALENKVADFEAT 2094
Q L+ KV A TLN+E L K +VE +K A+ ++ D +
Sbjct: 9 QELQQKVNKLTTANETLNNENLKLKSQ---------VVEYEKGNTPMVAVRKELDDLKNK 59
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
+ L ++ N ++ K +K AL + ++ + + L +K ++
Sbjct: 60 YSFLENKNTNLSNESKMFARQNK-ALTDENNMLKKKLGEL---------EKTYGISASKF 109
Query: 1913 LEAAKQ--ALEYKVADLEAAKTTLNDEL---ERKKDDNNAIIK------KALDKRISDLK 1767
E KQ +L+ + A+L+A L D+L ++D N+IIK KAL DL
Sbjct: 110 GEWMKQFESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDKDNQFKALQAERDDLA 169
Query: 1766 ADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKD 1587
A Q Q+ +N S + N + +++ DDKT+ D
Sbjct: 170 AKINQLTQKCQLNDAEKNALQAKLDSSENSLNESRNQCNFI------KQQLDDKTSQCND 223
Query: 1586 L---------VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAI 1434
L AE + +N++ + +++KS+ +K++ EDE+ + + +MK
Sbjct: 224 LGTKLSQADQTIAEKIE-AINQLNNEIDNKSKIIKQY-----EDELAKSKEDSEELMKKY 277
Query: 1433 REEELRKEKDGKSALVE-NGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK 1257
+EE + +KD ++ E + AE +K L+ L ++ E++++ + DK
Sbjct: 278 QEETDKLKKDSENLQNELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQIKVLQDDK 337
Query: 1256 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 1077
S L E E E + +K+ + + + L + ++ E L+K+ DL
Sbjct: 338 SNLEIQREKLEQEVEELKKSQQENDEKYQKEKEDLTQTVNNQNNEISNLKKQNEDLSNST 397
Query: 1076 ASLTDNQEGHEAEIERK---LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKV 906
+ +N +++ + LE N +N+ + D+ ++ ++ E+ L+ +
Sbjct: 398 TNEINNLNKQIQDLQNQKSDLEKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKET 457
Query: 905 SDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD 726
++ T + NNE+++ NE NE+ L+ VK+ L + + I D++ K +
Sbjct: 458 ENLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVKEDLTNTITTKDDEIKDLK----KQN 513
Query: 725 DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ-EDLNKESKEKQDL 549
+ + + L+K+ +L ++ D LK+ N L E + Q +D+N K QDL
Sbjct: 514 EDLQNQNNDLEKQKEDLNNTVAN-KDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDL 572
Query: 548 EKRVLELTSKLEK 510
E +V +L K+++
Sbjct: 573 EDKVTDLEGKIDE 585
Score = 108 bits (269), Expect = 3e-20
Identities = 141/624 (22%), Positives = 264/624 (42%), Gaps = 42/624 (6%)
Frame = -2
Query: 2258 QALENKVGDFEAAIATLNDELL---NEKDDKKCIVNDRNIVEADKQALENKVADFEATIA 2088
++L+ + + +A I L D+L E+D I+ D+ + +AL+ + D A I
Sbjct: 117 ESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDK---DNQFKALQAERDDLAAKI- 172
Query: 2087 TLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDE---LLNEKDDKKCIVNDRN 1917
N+ K + +A+K AL++K+ E ++ ++ + + DDK ND
Sbjct: 173 -------NQLTQKCQLNDAEKNALQAKLDSSENSLNESRNQCNFIKQQLDDKTSQCNDLG 225
Query: 1916 I-LEAAKQALEYKVADLEAAKTTLN----------DELERKKDDNNAIIKKALDKRISDL 1770
L A Q + K+ + ++ DEL + K+D+ ++KK ++
Sbjct: 226 TKLSQADQTIAEKIEAINQLNNEIDNKSKIIKQYEDELAKSKEDSEELMKKYQEE----- 280
Query: 1769 KADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIK 1590
D ++D E+ L ELQ +K +
Sbjct: 281 -TDKLKKDSEN--------------------------------LQNELQNQKS-----LA 302
Query: 1589 DLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKE 1410
+L A++ G + V L+ + +L E++ +VL+ SNL I + E+E+ +
Sbjct: 303 ELNASDKGN--LQSAVKQLQDDNSNL------EKQIKVLQDDKSNLEIQREKLEQEVEEL 354
Query: 1409 KDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEG 1230
K + EN E + EK+ L +TV + + + + +E+ + + L + +
Sbjct: 355 KKSQQ---ENDEKYQKEKEDLTQTV-NNQNNEISNLKKQNEDLSNSTTNEINNLNKQIQD 410
Query: 1229 CEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 1050
+ +K EK D T+ + ND L +L ++ E Q EK E +N S T N +
Sbjct: 411 LQNQKSDLEKQNADYNNTVSNNNDELA-NLKKLNQELQN-EKSNLQKETENLSNTVNDKN 468
Query: 1049 HEAEIERKL------EASNL------------THNDELHKEKDDKESIMNDLDHVKAERQ 924
+E E +K E NL T +DE+ K E + N + ++ +++
Sbjct: 469 NEIEELKKQNEDLQNEKQNLQKVKEDLTNTITTKDDEIKDLKKQNEDLQNQNNDLEKQKE 528
Query: 923 VLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 744
L + V++ ++ + L N+ QQ + N+ ++ + L+ Q LE +V DLE I ++
Sbjct: 529 DLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLEDKVTDLEGKIDEMTA 588
Query: 743 KTGKDDDYNEAEKQTLKKRISELE-------EAISILTDKAKKLLKDINIWLSEVTELQE 585
+ NE + +K R +L+ + + L L I+ S+V +L+
Sbjct: 589 E-------NEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVNDLKS 641
Query: 584 DLNKESKEKQDLEKRVLELTSKLE 513
+ K+K DLEK+V EL LE
Sbjct: 642 QKDSLEKDKSDLEKKVKELEEALE 665
Score = 106 bits (265), Expect = 9e-20
Identities = 122/603 (20%), Positives = 249/603 (41%), Gaps = 18/603 (2%)
Frame = -2
Query: 2273 LEAAKQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEAT 2094
L+ K LE + D+ ++ NDEL N K + + N+++ ++ + + L N V D
Sbjct: 411 LQNQKSDLEKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKETENLSNTVNDKNNE 470
Query: 2093 IATLNDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNI 1914
I +EL + +D ++ +KQ L+ I T +DE+ + K + + N N
Sbjct: 471 I----EELKKQNED----LQNEKQNLQKVKEDLTNTITTKDDEIKDLKKQNEDLQNQNND 522
Query: 1913 LEAAKQALEYKVADLEAAKTTLND------ELERKKDDNNAIIKKA---LDKRISDL--K 1767
LE K+ L VA+ ++ L + E +K++D+ +KK+ L+ +++DL K
Sbjct: 523 LEKQKEDLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLEDKVTDLEGK 582
Query: 1766 ADAPQRDQEDDMNALIXXXXXXXXXXXXXXKIVSNLEVNILILHEELQKEKDDKTALIKD 1587
D + E M + + V L N L L ++ D L
Sbjct: 583 IDEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVNDLKSQ 642
Query: 1586 LVAAEPGKRTVNEIVSHLES-----KSRSLKEHFLREEEDEVLERSASNLAIMKAIREEE 1422
+ E K + + V LE K+ SL EE + L + L + +
Sbjct: 643 KDSLEKDKSDLEKKVKELEEALEDEKNSSLLNSSNFNEESQKLMDKINELTKQNREKNQN 702
Query: 1421 LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE--EELRKEKVDKSAL 1248
++K ++ K+ L +N + ++K + +AS + + ++ E+ KE+ + L
Sbjct: 703 IKKLENEKANLQQNNDNLNQRLDNVKKQYEDLQASKSELVGKYNDLVEKFNKERQTNNEL 762
Query: 1247 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 1068
++ + A+KQ +++ +DL ASL
Sbjct: 763 SQQNQ-----------------------------------AQKQQIQQLMNDL----ASL 783
Query: 1067 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETT 888
D + ++I +K NDE + K + N + +K ES + +
Sbjct: 784 RDGK----SDIVQKYNDLVAKFNDERQEAAKTKSDLQNQIQQLKDALAKAESNQKETQNK 839
Query: 887 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 708
N++L+++ D +++ E L++ Q +++ +LE+ + + + N +
Sbjct: 840 LDISNSDLEKEKDKSKSLEEELAALKSKLQQVQEEKANLESDLEN-------ERQNNSSS 892
Query: 707 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 528
L ++S+L++ L ++ +L D+ SE+ ++ DL+ + QDLE ++ ++
Sbjct: 893 NAELSDKLSKLQQENRDLVNQINQLQNDLKQKESEIQKVSSDLDNLNNVIQDLESQMNDM 952
Query: 527 TSK 519
K
Sbjct: 953 QGK 955
Score = 85.1 bits (209), Expect = 3e-13
Identities = 135/642 (21%), Positives = 267/642 (41%), Gaps = 61/642 (9%)
Frame = -2
Query: 2261 KQALENKVGDFEAAIATLNDELLNEKDDKKCIVNDRNIVEADKQALENKVADFEATIATL 2082
+Q D + I L D L + ++K N +I +D + ++K E +A L
Sbjct: 805 RQEAAKTKSDLQNQIQQLKDALAKAESNQKETQNKLDISNSDLEKEKDKSKSLEEELAAL 864
Query: 2081 NDELLNEKDDKKCIVEADKQALESKVSVFEAAIATLNDELLNEKDDKKCIVNDRNILEAA 1902
+L + ++K +E+D LE++ ++ A L+D+L + + + +VN N L+
Sbjct: 865 KSKL-QQVQEEKANLESD---LENERQNNSSSNAELSDKLSKLQQENRDLVNQINQLQND 920
Query: 1901 KQALEYKVADLEAAKTTLNDELERKKDDNNAIIKK--ALDKRISDLKADAPQRDQE-DDM 1731
+ E ++ + + LN+ ++ + N + K L K++S+L D ++D+ DD+
Sbjct: 921 LKQKESEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDELSKKLSNLVDDNERKDKLIDDL 980
Query: 1730 NALIXXXXXXXXXXXXXXKI-------VSNLEVNILILHEELQK----EKDDKTALIKDL 1584
N+ + ++N +L + E+LQ+ EKD + + L
Sbjct: 981 NSQLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLKVIEDLQRSLSEEKDKNNSSLLSL 1040
Query: 1583 VAAEPGKRTVNEIVSHLESKSRSLKE-------------HFLREEEDEVLERSASNLAIM 1443
+ E V+ LE + +LK+ + LRE D + + L +
Sbjct: 1041 GDFGKENALLKEKVADLEKQVSNLKQENETQNEEISKLNNDLREAADYIEKIKQQYLKLK 1100
Query: 1442 K---AIREE--ELRKEKDGKSALVE--NGEGCEAEKQ--GLEKTVLERRASNLDTMDAIH 1290
K A++EE +L+ E D ++ ++ N + + E+Q L T+ E ++ + +
Sbjct: 1101 KENQALKEEISKLKAENDEHNSTIDQLNDDKRDLEEQLKELNITLDEEKSKSFSLNENAS 1160
Query: 1289 EEELRKEKVD-------KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 1131
EE K+ ++ KS + +N E EAE V + S ND L+ +
Sbjct: 1161 EELKNKDDINDGLKSQLKSQVQQNKE-IEAENHNLRSQVDQYK----SSNDELETQISNY 1215
Query: 1130 MAEKQALEKRCSDLEAKNASLTDNQEGHEA---EIERKLEASNLTHNDELHKEKDDKESI 960
E L+ S E KN + + + + ++E L S +N+ + D+ +
Sbjct: 1216 QEENSNLQDLLSSSENKNKDINEQNKQLKQKLQQLENSLRESENKYNNLVKSNCDEITKL 1275
Query: 959 MNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRV 780
L + S+ ++ LNN L + N+ N+R LE Q L+ ++
Sbjct: 1276 SQQLQDAMQDNAKYSSEKDNLIKKLKELNNNLNVQKSQNKQIENQRSFLERENQRLKSQI 1335
Query: 779 LDL------EATIHDI--EMKT-GKDDDYNEAEKQTLKKRISELEEA---ISILTDKAKK 636
+L I D+ +M+T ++++ + +++R+ LE +SI ++ +
Sbjct: 1336 SELSKNQIPSVDIEDLKYQMRTLTIENEHLKKNNDEIRQRMRHLESTNAQLSIQNNQNEL 1395
Query: 635 LLKDIN---IWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 519
L + +WLS + K KE DL + + SK
Sbjct: 1396 KLCTLEQRCVWLSGAHD------KLRKENFDLSSTIDTMNSK 1431