BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Papaver30_contig00013703
         (3067 letters)

Database: ./nr 
           77,306,371 sequences; 28,104,191,420 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_008219582.1| PREDICTED: DNA topoisomerase 2-binding prote...  1004   0.0  
ref|XP_007019209.1| Topbp1, putative isoform 1 [Theobroma cacao]...   989   0.0  
ref|XP_007019210.1| Topbp1, putative isoform 2 [Theobroma cacao]...   987   0.0  
ref|XP_007227054.1| hypothetical protein PRUPE_ppa000738mg [Prun...   969   0.0  
ref|XP_007019212.1| Topbp1, putative isoform 4 [Theobroma cacao]...   952   0.0  
ref|XP_012464226.1| PREDICTED: DNA topoisomerase 2-binding prote...   951   0.0  
ref|XP_010320793.1| PREDICTED: DNA topoisomerase 2-binding prote...   930   0.0  
gb|KJB80623.1| hypothetical protein B456_013G107700 [Gossypium r...   929   0.0  
ref|XP_007019211.1| Topbp1, putative isoform 3 [Theobroma cacao]...   928   0.0  
ref|XP_006345369.1| PREDICTED: DNA topoisomerase 2-binding prote...   920   0.0  
ref|XP_009788828.1| PREDICTED: DNA topoisomerase 2-binding prote...   916   0.0  
ref|XP_009605009.1| PREDICTED: DNA topoisomerase 2-binding prote...   914   0.0  
ref|XP_008444199.1| PREDICTED: DNA topoisomerase 2-binding prote...   911   0.0  
ref|XP_009788827.1| PREDICTED: DNA topoisomerase 2-binding prote...   908   0.0  
emb|CDP16447.1| unnamed protein product [Coffea canephora]            903   0.0  
ref|XP_014502699.1| PREDICTED: DNA topoisomerase 2-binding prote...   899   0.0  
ref|XP_007019213.1| Topbp1, putative isoform 5 [Theobroma cacao]...   899   0.0  
ref|XP_012464227.1| PREDICTED: DNA topoisomerase 2-binding prote...   892   0.0  
ref|XP_009788829.1| PREDICTED: DNA topoisomerase 2-binding prote...   888   0.0  
ref|XP_011091797.1| PREDICTED: DNA topoisomerase 2-binding prote...   881   0.0  

>ref|XP_008219582.1| PREDICTED: DNA topoisomerase 2-binding protein 1 [Prunus mume]
          Length = 983

 Score = 1004 bits (2595), Expect = 0.0
 Identities = 537/1003 (53%), Positives = 682/1003 (67%), Gaps = 59/1003 (5%)
 Frame = -3

Query: 2891 MERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSH 2712
            M +T +FKG+NVF+SRNLV P+ FDA+HD+LK NGA VFLCCDPSR+G +DYHVI+   H
Sbjct: 1    MLKTTTFKGANVFMSRNLVPPEIFDALHDALKLNGANVFLCCDPSRTGPDDYHVIASSDH 60

Query: 2711 DKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIE 2532
            +KFEDL AKGC LLG + V SC  ++RALPK +GFTCCLAMDG KVLA+GF+  EK KIE
Sbjct: 61   EKFEDLRAKGCNLLGPQCVFSCANQHRALPK-QGFTCCLAMDGFKVLASGFEGDEKVKIE 119

Query: 2531 KLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPH 2352
            KLVTAMGGV   +A+LD +FVI KNVL+GKYKW L+TLKKP++TINWL QCW+EHR VP 
Sbjct: 120  KLVTAMGGVLHAKASLDVNFVIVKNVLAGKYKWALNTLKKPIVTINWLSQCWNEHRNVPQ 179

Query: 2351 EPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRV 2172
            +  RVLPFSGL I  TRI AD RKE+E LI  NGG+YS +LT+ CTHLISD PEGDKY+V
Sbjct: 180  DSFRVLPFSGLMISVTRIPADERKEIEKLITENGGKYSAELTKKCTHLISDVPEGDKYKV 239

Query: 2171 AQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTNS 1992
            AQ+WGHIRIVT+ W   S +R+  L ED+Y VQG ++S+N  ++     +N Q   S N 
Sbjct: 240  AQRWGHIRIVTRKWFDQSISRRACLNEDSYPVQGGSISSNKSVRGCFTLQNSQRSSSGNL 299

Query: 1991 QSGPGPIAADS---------------EATLSQNISSAISDSTVIMKGEEGIEAPPPSKIE 1857
            QS P  + ADS               EAT+SQN+++  S +  ++K E+  +APP   +E
Sbjct: 300  QSVPPSVVADSNLTAAPYSGTMDSDLEATVSQNMTTMFSHAPHVVKNEDS-KAPP---LE 355

Query: 1856 DKEET-LDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDR 1680
             K E  LD CVADDSQSED+ LYLS+CRI LVGF A+EMR+LVN +RRGGGSRYM+FND+
Sbjct: 356  SKSEAYLDGCVADDSQSEDNDLYLSECRISLVGFKASEMRRLVNMIRRGGGSRYMSFNDK 415

Query: 1679 LTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKD 1500
            LTHIVVGTP+E +++E+R + A GVI+VVR  WL+DCDREKKE+PV  +H+  DL+LP+ 
Sbjct: 416  LTHIVVGTPSEIQKKEVRGFAALGVIHVVRTTWLEDCDREKKEIPVLPKHIAYDLVLPEG 475

Query: 1499 SVFSDKATKIGTRQGHNLITPPSVPDHLTQCFRPSM----------PREQTEERKTMEAS 1350
            ++    +T  GT    +L + PS   H      P M          P    +  K+MEA+
Sbjct: 476  ALIGMTSTIQGTISTTHL-SIPSDQLHGNTSAAPGMGSLEKKREKKPEINMKGDKSMEAA 534

Query: 1349 ------------------------------KQESSMVKKNSSNIXXXXXXXXXXXFPLDR 1260
                                          + +SS+     S++           FP DR
Sbjct: 535  VGPSKWSKLPVINGKSKVQLNNTIDGRLTMQYDSSVQNGKESSVFKGRLFCFSNSFPEDR 594

Query: 1259 RAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDA 1080
            R +I++W+ QGGG++VDG  +  V+FT+ECHG++T   +V  +QTT VS+HWIRSCLED 
Sbjct: 595  RGDIIQWVNQGGGDVVDGYLKQKVHFTIECHGVIT--SSVDVAQTTYVSSHWIRSCLEDG 652

Query: 1079 CMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKV 900
            C+ DV SHI+Y+P+PC+IPLPGFE FRFCVSQYEEKDRLLLRNLCFVLGAKF EKL+KKV
Sbjct: 653  CLLDVSSHILYAPLPCRIPLPGFENFRFCVSQYEEKDRLLLRNLCFVLGAKFGEKLTKKV 712

Query: 899  THLLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLAT 720
            THLLCKFTNGPKY+AAC  G+  +T+EW+ EC+++N VV+   F PK++TA+DREAGL T
Sbjct: 713  THLLCKFTNGPKYQAACIKGIHPITAEWVYECVKKNKVVALDQFYPKKVTAEDREAGLCT 772

Query: 719  MSQYTTQAARMIS---GEDVPSQSQGQSQFAMNSSRTFGKKSTNLSVEAEYPSATNKKRA 549
            MSQY TQA +MIS     + PSQSQ       +S    G ++ +L  EA  PS   KK A
Sbjct: 773  MSQYPTQAVQMISAGNSSECPSQSQ---DLRTSSGENIGSRNDSLREEASEPSFCYKK-A 828

Query: 548  KVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSK 369
            +VS ++ +  LL   V   + +CT    K    G +    S  VPDVA+AIEDLLE++SK
Sbjct: 829  RVSEDDGEKGLLSSGVHLRIPACTAGDRKVKSSGEV----SQVVPDVASAIEDLLEQTSK 884

Query: 368  IQDMALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQ 189
            I D    GR++ D SIFSPD S + Q+ + SHS I +S  WL+R      GN+ D     
Sbjct: 885  IHDQKSPGRSLCDSSIFSPDCSALRQDHSDSHSVIGLSRHWLNRA-----GNKDDIHDPS 939

Query: 188  GVNEHRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSSM 60
            G  +   YDGFSETQTESQVV YEEDLSGRQM+IDR RTRSS+
Sbjct: 940  GEQKAGFYDGFSETQTESQVVGYEEDLSGRQMLIDRVRTRSSL 982


>ref|XP_007019209.1| Topbp1, putative isoform 1 [Theobroma cacao]
            gi|508724537|gb|EOY16434.1| Topbp1, putative isoform 1
            [Theobroma cacao]
          Length = 979

 Score =  989 bits (2556), Expect = 0.0
 Identities = 542/997 (54%), Positives = 691/997 (69%), Gaps = 52/997 (5%)
 Frame = -3

Query: 2894 VMERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPS 2715
            +M +TK+FKGS+VF+SRNLV P+ FD +H  LK +GA+VFLCCDPSR+G +D+HVIS   
Sbjct: 2    MMLKTKAFKGSSVFMSRNLVPPEVFDKLHGVLKDSGAQVFLCCDPSRNGPDDFHVISSID 61

Query: 2714 HDKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKI 2535
            H+KFEDL AKGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KI
Sbjct: 62   HEKFEDLRAKGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKI 120

Query: 2534 EKLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVP 2355
            EKLVTAMGGV  T+A+LD  FV+ KNVL+ KYKW L+ LKKP++T++WLYQCW EHR+VP
Sbjct: 121  EKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVP 180

Query: 2354 HEPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYR 2175
             E  RVLPFSGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+
Sbjct: 181  QESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYK 240

Query: 2174 VAQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTN 1995
            VA++WGH+ IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +
Sbjct: 241  VARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGS 300

Query: 1994 SQSGPGPIAADS---------------EATLSQNISSAISDSTVIMKGEEGIEAPPPSKI 1860
            S S    + +D                EATLSQNI S +SD+ VI+K E+G EAP    +
Sbjct: 301  SLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---L 356

Query: 1859 EDKEET-LDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFND 1683
            +   ET LD CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND
Sbjct: 357  QPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCND 416

Query: 1682 RLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPK 1503
            +LTHIVVGTP+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPK
Sbjct: 417  KLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPK 476

Query: 1502 DSVFSDKATKIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEA 1353
            DSV S K   IG   + Q  + +   S       + D+L    + +   +++ E  T+ +
Sbjct: 477  DSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRS 535

Query: 1352 SKQE-----------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWI 1236
            SKQ                   S+V   KN  SS +           FP DRRAEIVEW+
Sbjct: 536  SKQGVPPTVNSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWV 595

Query: 1235 KQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSH 1056
             QGGGE+VD   + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG H
Sbjct: 596  DQGGGEVVDDHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCH 653

Query: 1055 IIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFT 876
            I+YSP+PC+IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT
Sbjct: 654  ILYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFT 713

Query: 875  NGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQA 696
            +GPKYEAACKWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA
Sbjct: 714  SGPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQA 773

Query: 695  ARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDK 525
             +M+S  D+PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+
Sbjct: 774  VQMMS-VDIPSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQ 829

Query: 524  IDLLP--LDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMAL 351
              LL   + +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SKI D   
Sbjct: 830  NGLLASVVHLCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKIHDQKS 886

Query: 350  SGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHR 171
              R   D+SIFS D + + Q+   SHS I +S  WL+R  K+D     ++ S  G     
Sbjct: 887  PERNGCDKSIFSSDRTGLCQDHTDSHSVIGLSRHWLNRTVKKD-----ETCSYSGDGNAG 941

Query: 170  TYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSSM 60
             YDGFSETQTESQVV YEEDLSGRQM+IDR RTRSSM
Sbjct: 942  LYDGFSETQTESQVVGYEEDLSGRQMLIDRVRTRSSM 978


>ref|XP_007019210.1| Topbp1, putative isoform 2 [Theobroma cacao]
            gi|508724538|gb|EOY16435.1| Topbp1, putative isoform 2
            [Theobroma cacao]
          Length = 980

 Score =  987 bits (2551), Expect = 0.0
 Identities = 543/998 (54%), Positives = 692/998 (69%), Gaps = 53/998 (5%)
 Frame = -3

Query: 2894 VMERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPS 2715
            +M +TK+FKGS+VF+SRNLV P+ FD +H  LK +GA+VFLCCDPSR+G +D+HVIS   
Sbjct: 2    MMLKTKAFKGSSVFMSRNLVPPEVFDKLHGVLKDSGAQVFLCCDPSRNGPDDFHVISSID 61

Query: 2714 HDKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKI 2535
            H+KFEDL AKGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KI
Sbjct: 62   HEKFEDLRAKGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKI 120

Query: 2534 EKLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVP 2355
            EKLVTAMGGV  T+A+LD  FV+ KNVL+ KYKW L+ LKKP++T++WLYQCW EHR+VP
Sbjct: 121  EKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVP 180

Query: 2354 HEPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYR 2175
             E  RVLPFSGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+
Sbjct: 181  QESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYK 240

Query: 2174 VAQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTN 1995
            VA++WGH+ IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +
Sbjct: 241  VARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGS 300

Query: 1994 SQSGPGPIAADS---------------EATLSQNISSAISDSTVIMKGEEGIEAPPPSKI 1860
            S S    + +D                EATLSQNI S +SD+ VI+K E+G EAP    +
Sbjct: 301  SLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---L 356

Query: 1859 EDKEET-LDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFND 1683
            +   ET LD CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND
Sbjct: 357  QPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCND 416

Query: 1682 RLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPK 1503
            +LTHIVVGTP+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPK
Sbjct: 417  KLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPK 476

Query: 1502 DSVFSDKATKIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEA 1353
            DSV S K   IG   + Q  + +   S       + D+L    + +   +++ E  T+ +
Sbjct: 477  DSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRS 535

Query: 1352 SKQE-----------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWI 1236
            SKQ                   S+V   KN  SS +           FP DRRAEIVEW+
Sbjct: 536  SKQGVPPTVNSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWV 595

Query: 1235 KQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSH 1056
             QGGGE+VD   + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG H
Sbjct: 596  DQGGGEVVDDHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCH 653

Query: 1055 IIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFT 876
            I+YSP+PC+IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT
Sbjct: 654  ILYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFT 713

Query: 875  NGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQA 696
            +GPKYEAACKWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA
Sbjct: 714  SGPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQA 773

Query: 695  ARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDK 525
             +M+S  D+PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+
Sbjct: 774  VQMMS-VDIPSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQ 829

Query: 524  IDLLP--LDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMAL 351
              LL   + +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SKI D   
Sbjct: 830  NGLLASVVHLCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKIHDQKS 886

Query: 350  SGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHR 171
              R   D+SIFS D + + Q+   SHS I +S  WL+R  K+D     ++ S  G     
Sbjct: 887  PERNGCDKSIFSSDRTGLCQDHTDSHSVIGLSRHWLNRTVKKD-----ETCSYSGDGNAG 941

Query: 170  TYDGFSETQTESQVVV-YEEDLSGRQMMIDRHRTRSSM 60
             YDGFSETQTESQVVV YEEDLSGRQM+IDR RTRSSM
Sbjct: 942  LYDGFSETQTESQVVVGYEEDLSGRQMLIDRVRTRSSM 979


>ref|XP_007227054.1| hypothetical protein PRUPE_ppa000738mg [Prunus persica]
            gi|462423990|gb|EMJ28253.1| hypothetical protein
            PRUPE_ppa000738mg [Prunus persica]
          Length = 1018

 Score =  969 bits (2504), Expect = 0.0
 Identities = 530/1037 (51%), Positives = 677/1037 (65%), Gaps = 93/1037 (8%)
 Frame = -3

Query: 2891 MERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSH 2712
            M +T +FKG+NVF+SRNLV P+ FDA+HD+LK NGA VFLCCDPSR+G +DYHVI+   H
Sbjct: 1    MLKTTTFKGANVFMSRNLVPPEIFDALHDALKLNGANVFLCCDPSRTGPDDYHVIASSDH 60

Query: 2711 DKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIE 2532
            +KFEDL AKGC LLG + V SC  ++RALPK +GFTCCLAMDG KVLA+GF+  EK KIE
Sbjct: 61   EKFEDLRAKGCNLLGPQCVFSCANQHRALPK-QGFTCCLAMDGFKVLASGFEGDEKAKIE 119

Query: 2531 KLVTAMGGVFQTRAALDTDFVICKNVLSGKYK----------WGLHTLKKPVITINWLYQ 2382
            KLVTAMGGV   +A+LD +FVI KNVL+GKYK          W L+TLKKP++TINWL Q
Sbjct: 120  KLVTAMGGVLHAKASLDVNFVIVKNVLAGKYKAITELVLFMQWALNTLKKPIVTINWLSQ 179

Query: 2381 CWSEHRLVPHEPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRN------ 2220
            CW+EHR VP +  RVLPFSGL I  TRI AD RKE+E LI  NGG+YS +LT+N      
Sbjct: 180  CWNEHRNVPQDSFRVLPFSGLMISVTRIPADERKEIEKLITENGGKYSAELTKNKELESY 239

Query: 2219 CTHLISDA-------------------PEGDKYRVAQKWGHIRIVTKDWLRDSFNRKVYL 2097
                +SD                    PEGDKY+VAQ+WGHIRIVT+ W   S +R+  L
Sbjct: 240  VYFSMSDLHNTSRLQLNEANLEIFMFFPEGDKYKVAQRWGHIRIVTRKWFDQSISRRACL 299

Query: 2096 PEDAYLVQGITMSANHVLKNKLREKNYQDKKSTNSQSGPGPIAADS-------------- 1959
             ED+Y VQG ++S+N  ++     +N Q   S N QS P  + ADS              
Sbjct: 300  NEDSYPVQGGSISSNKSVRGCFTLQNSQRSSSGNLQSVPPSVVADSNLTAAPCSGTMDSD 359

Query: 1958 -EATLSQNISSAISDSTVIMKGEEGIEAPPPSKIEDKEET-LDSCVADDSQSEDSGLYLS 1785
             EAT+SQN+++  S +  ++K E+  +APP   +E K E  LD CVADDSQSED+ LYLS
Sbjct: 360  LEATVSQNMTTMFSHAPHVVKNEDS-KAPP---LESKSEAYLDGCVADDSQSEDNDLYLS 415

Query: 1784 DCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIVVGTPTENERRELRRYTAAGV 1605
            +CRI LVGF  +EMR+LVN +RRGGGSRYM+FND+LTHIVVGTP+E +++E+R + A GV
Sbjct: 416  ECRISLVGFKVSEMRRLVNMIRRGGGSRYMSFNDKLTHIVVGTPSEIQKKEVRGFAALGV 475

Query: 1604 IYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVFSDKATKIGTRQGHNLITPPSVP 1425
            I+VVR  WLDDCDREKKE+PV  +H+  DL+LP+ ++    +T  GT    +L  P    
Sbjct: 476  IHVVRTTWLDDCDREKKEIPVLPKHIAYDLVLPEGALIGMTSTIQGTISTTHLSIPSDQL 535

Query: 1424 DHLTQCF---------RPSMPREQTEERKTMEAS-------------------------- 1350
               T            R   P    +  K+MEA+                          
Sbjct: 536  HGNTSAATGMGSLEKKREKKPEINMKGDKSMEAAVGPSKWSKLPVINGKSKVQLNNTIDG 595

Query: 1349 ----KQESSMVKKNSSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDGQSEFNVNF 1182
                + +SS+     S++           FP DRR +I++W+ QGGG++VDG  +  V+F
Sbjct: 596  RLMMQYDSSVQNGKESSVFKGRLFCFSNSFPEDRRGDIIQWVNQGGGDVVDGDLKQKVHF 655

Query: 1181 TVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKIPLPGFEAF 1002
            T+ECHG++T   +V  +QTT VS+HWIRSCLED C+ DV SHI+Y+P+PC+IPLPGFE F
Sbjct: 656  TIECHGVIT--SSVDVAQTTYVSSHWIRSCLEDGCLLDVSSHILYAPLPCRIPLPGFENF 713

Query: 1001 RFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACKWGMQTVTS 822
            RFCVSQYEEKDRLLLRNLCFVLGAKF EKL+KKVTHLLCKFTNGPKY+AAC  G+  +T+
Sbjct: 714  RFCVSQYEEKDRLLLRNLCFVLGAKFGEKLTKKVTHLLCKFTNGPKYQAACIKGIHPITA 773

Query: 821  EWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMIS---GEDVPSQSQG 651
            EW+ EC+++N VV+   F PK++TA+DREAGL TMSQY TQA +MIS     + PSQSQ 
Sbjct: 774  EWVYECVKKNKVVALDQFYPKKVTAEDREAGLCTMSQYPTQAVQMISAGNSSECPSQSQ- 832

Query: 650  QSQFAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKIDLLPLDVCANVSSCTMK 471
                  +S    G ++ +L  EA  PS  NKK A+VS ++ +  LL   V   + +CT  
Sbjct: 833  --DLRTSSGENIGSRNDSLREEASEPSFCNKK-ARVSEDDGEKGLLSSGVHLRIPACTTG 889

Query: 470  SIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRTISDRSIFSPDHSIITQ 291
              K    G +    S  VPDVA+AIEDLLE++SKI D    GR++ D SIFSP+ S + Q
Sbjct: 890  DRKVKSSGEV----SQVVPDVASAIEDLLEQTSKIHDQKSPGRSLCDSSIFSPECSALRQ 945

Query: 290  NPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDGFSETQTESQVVVYEED 111
            + + +HS I +S  WL+R  K+DD +        G+     YDGFSETQTESQVV YEED
Sbjct: 946  DHSDAHSVIGLSRHWLNRAGKKDDIHYPSEEQKAGL-----YDGFSETQTESQVVGYEED 1000

Query: 110  LSGRQMMIDRHRTRSSM 60
            LSGRQM+IDR RTRSS+
Sbjct: 1001 LSGRQMLIDRVRTRSSL 1017


>ref|XP_007019212.1| Topbp1, putative isoform 4 [Theobroma cacao]
            gi|508724540|gb|EOY16437.1| Topbp1, putative isoform 4
            [Theobroma cacao]
          Length = 971

 Score =  952 bits (2461), Expect = 0.0
 Identities = 522/974 (53%), Positives = 670/974 (68%), Gaps = 52/974 (5%)
 Frame = -3

Query: 2894 VMERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPS 2715
            +M +TK+FKGS+VF+SRNLV P+ FD +H  LK +GA+VFLCCDPSR+G +D+HVIS   
Sbjct: 2    MMLKTKAFKGSSVFMSRNLVPPEVFDKLHGVLKDSGAQVFLCCDPSRNGPDDFHVISSID 61

Query: 2714 HDKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKI 2535
            H+KFEDL AKGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KI
Sbjct: 62   HEKFEDLRAKGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKI 120

Query: 2534 EKLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVP 2355
            EKLVTAMGGV  T+A+LD  FV+ KNVL+ KYKW L+ LKKP++T++WLYQCW EHR+VP
Sbjct: 121  EKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVP 180

Query: 2354 HEPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYR 2175
             E  RVLPFSGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+
Sbjct: 181  QESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYK 240

Query: 2174 VAQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTN 1995
            VA++WGH+ IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +
Sbjct: 241  VARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGS 300

Query: 1994 SQSGPGPIAADS---------------EATLSQNISSAISDSTVIMKGEEGIEAPPPSKI 1860
            S S    + +D                EATLSQNI S +SD+ VI+K E+G EAP    +
Sbjct: 301  SLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---L 356

Query: 1859 EDKEET-LDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFND 1683
            +   ET LD CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND
Sbjct: 357  QPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCND 416

Query: 1682 RLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPK 1503
            +LTHIVVGTP+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPK
Sbjct: 417  KLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPK 476

Query: 1502 DSVFSDKATKIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEA 1353
            DSV S K   IG   + Q  + +   S       + D+L    + +   +++ E  T+ +
Sbjct: 477  DSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRS 535

Query: 1352 SKQE-----------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWI 1236
            SKQ                   S+V   KN  SS +           FP DRRAEIVEW+
Sbjct: 536  SKQGVPPTVNSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWV 595

Query: 1235 KQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSH 1056
             QGGGE+VD   + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG H
Sbjct: 596  DQGGGEVVDDHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCH 653

Query: 1055 IIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFT 876
            I+YSP+PC+IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT
Sbjct: 654  ILYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFT 713

Query: 875  NGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQA 696
            +GPKYEAACKWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA
Sbjct: 714  SGPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQA 773

Query: 695  ARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDK 525
             +M+S  D+PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+
Sbjct: 774  VQMMS-VDIPSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQ 829

Query: 524  IDLLP--LDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMAL 351
              LL   + +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SKI D   
Sbjct: 830  NGLLASVVHLCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKIHDQKS 886

Query: 350  SGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHR 171
              R   D+SIFS D + + Q+   SHS I +S  WL+R  K+D     ++ S  G     
Sbjct: 887  PERNGCDKSIFSSDRTGLCQDHTDSHSVIGLSRHWLNRTVKKD-----ETCSYSGDGNAG 941

Query: 170  TYDGFSETQTESQV 129
             YDGFSETQTESQV
Sbjct: 942  LYDGFSETQTESQV 955


>ref|XP_012464226.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X1
            [Gossypium raimondii]
          Length = 985

 Score =  951 bits (2457), Expect = 0.0
 Identities = 522/998 (52%), Positives = 663/998 (66%), Gaps = 55/998 (5%)
 Frame = -3

Query: 2885 RTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSHDK 2706
            + K+F GSNVF+SRNLV P+ FD +H  LK NGA+VFLCCDPSR+G +D+HVIS   H+K
Sbjct: 6    KAKAFMGSNVFMSRNLVPPEVFDKLHGVLKDNGAQVFLCCDPSRNGPDDFHVISSFDHEK 65

Query: 2705 FEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKL 2526
            FEDL AKGC L+G + VISC  ENRALPK +GF+CCLAMDG+KVLA+GFD  EK KIEKL
Sbjct: 66   FEDLRAKGCNLIGPQCVISCANENRALPK-QGFSCCLAMDGLKVLASGFDMDEKVKIEKL 124

Query: 2525 VTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPHEP 2346
            V AMGGV  T+A+LD  FVI KNVL+ KYKW L+ LKKP++TI WLYQCWSEHR+VP E 
Sbjct: 125  VIAMGGVLHTKASLDVSFVIVKNVLAAKYKWALNVLKKPIVTIQWLYQCWSEHRVVPQES 184

Query: 2345 CRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQ 2166
             RVLPF+GLTI  T I AD RKE+E LI+ NGG+YS +LT+ CTHLI D PEGDKY+VA+
Sbjct: 185  YRVLPFTGLTISVTGIRADERKEIEKLIIQNGGKYSAELTKKCTHLICDVPEGDKYKVAR 244

Query: 2165 KWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTNSQS 1986
            +WGH+ I+ + W      R+  L E++Y VQG + S+   +   L  ++ QDK   +S S
Sbjct: 245  RWGHVHIIVRKWFDQCIARRACLNEESYPVQGGSASSKKSVSGSLSAQHSQDKFRASSVS 304

Query: 1985 GPGPIA---------------ADSEATLSQNISSAISDSTVIMKGEEGIEAPPPSKIEDK 1851
                +                 D EA  SQN  S +SD+  I + E+G EAP    ++  
Sbjct: 305  ATSLVVPEFNMSTVPSTGLGDPDLEAAHSQNTPSVLSDAQAIFE-EDGGEAP---NLQPS 360

Query: 1850 EET-LDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLT 1674
             ET LD CVA+DSQSED+ LYLSDC+I LVGF A+EMRKLV  VRRGG SRYM+ N++LT
Sbjct: 361  TETKLDGCVANDSQSEDNDLYLSDCKISLVGFEASEMRKLVTMVRRGGASRYMSCNEKLT 420

Query: 1673 HIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSV 1494
            HIVVG P+E E++E+R   A+GVI+VV+  WL+DCDR+KKE+PV +RHV   L+LPKDS 
Sbjct: 421  HIVVGAPSELEKKEVRSIAASGVIHVVKTSWLEDCDRQKKEIPVHQRHVAYGLLLPKDSA 480

Query: 1493 FS--------------------DKATKIGTRQGHNLITPPSVPDHLTQCFRPSMPREQTE 1374
             S                    +  T + +  G +L   P +  +   C + ++   +  
Sbjct: 481  HSVRGAVTGIINSNQSKSSVPTNSGTGMPSSFGKSLDDKPKINMNGGSCLKATVGSSKQG 540

Query: 1373 ERKTMEAS-----KQESSMVKKN-----SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGG 1224
               T+ ++     KQ+   V +N     SS +           FP DRRAEIVEW+ QGG
Sbjct: 541  LLPTINSTSNFWQKQQYDSVVQNPKNGISSAVFKGKTFCFSVSFPEDRRAEIVEWVDQGG 600

Query: 1223 GEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYS 1044
            G++V+ Q + NVNF +ECHG++     ++ SQ T VSTHW+RSCLED C+ DVG HI+YS
Sbjct: 601  GQVVEDQVKKNVNFIIECHGVIPSC--ITDSQITYVSTHWVRSCLEDGCLLDVGRHILYS 658

Query: 1043 PVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPK 864
            P+PC+IP PGF+ FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPK
Sbjct: 659  PLPCQIPFPGFKNFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPK 718

Query: 863  YEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMI 684
            YEAACKWG+Q+VTSEWI EC+RQN VVS  PF PKE+TAQD+EAGL T+SQ+ TQAA+MI
Sbjct: 719  YEAACKWGIQSVTSEWIYECVRQNKVVSLDPFCPKEVTAQDQEAGLCTVSQFPTQAAKMI 778

Query: 683  SGEDVPSQSQGQSQ------FAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKI 522
            +  DVPSQ   Q Q        +      G ++     EAE  S  + KRA+   ++D+ 
Sbjct: 779  A-VDVPSQFTSQPQGLRTQDLGVKMGSITGDRNDGSRDEAE-QSNDHFKRARHLEDDDQN 836

Query: 521  DLLPLDVCANVSSCTMKSIKTSEGGN-IRDDG--SHDVPDVAAAIEDLLEESSKIQDMAL 351
            DLL     + V  C     + S G N +++ G  +  +PDV   I DLLE++SKI D   
Sbjct: 837  DLL----VSRVHLCEPFLNENSTGNNKLKNAGEAAQVLPDVDTVI-DLLEQTSKIHDQKS 891

Query: 350  SGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHR 171
              R   DRSIF  D + + Q+    HS I +S  WL+R  ++D+     SS  + VN   
Sbjct: 892  PERNGCDRSIFLSDCTGLRQDHTDPHSVIGLSRHWLNRNVRKDE----ISSHSRDVNAGS 947

Query: 170  TYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSSMT 57
             Y GFSETQTESQVV YEEDLSGRQM+IDR RTRSSMT
Sbjct: 948  LYGGFSETQTESQVVGYEEDLSGRQMLIDRVRTRSSMT 985


>ref|XP_010320793.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X1 [Solanum
            lycopersicum]
          Length = 991

 Score =  930 bits (2403), Expect = 0.0
 Identities = 499/1002 (49%), Positives = 647/1002 (64%), Gaps = 59/1002 (5%)
 Frame = -3

Query: 2891 MERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSH 2712
            M  TK F G+NVF+SRNLV P++FDA+HD+LK NGA+V LCCDPSR+   DYHVIS P H
Sbjct: 1    MMTTKVFNGANVFVSRNLVPPEQFDALHDALKLNGAQVLLCCDPSRNAPTDYHVISSPQH 60

Query: 2711 DKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIE 2532
            +KF DL AKGC L+G + V+SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK +I 
Sbjct: 61   EKFGDLQAKGCNLIGPQCVLSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVEIG 119

Query: 2531 KLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPH 2352
            KLV AMGGV QT+A+LD  FVI KNVL+ KYKW  + LKKP++TINWL+QCW EHRLVP 
Sbjct: 120  KLVIAMGGVLQTKASLDVSFVIVKNVLAAKYKWAYNILKKPIVTINWLHQCWKEHRLVPQ 179

Query: 2351 EPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRV 2172
            E  ++LPFSGLTI  TRI AD R++ME +I+ NGG+YS +LTR C+HLI D PEGDK++V
Sbjct: 180  ESFKILPFSGLTISVTRIPADERRDMEKIILQNGGKYSPELTRKCSHLICDVPEGDKFKV 239

Query: 2171 AQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQG-------ITMSANHVLKNKLREKNYQ 2013
            A++WG I  VTK W   S  R+  L E++Y VQ        + M+  H L+  +R  N Q
Sbjct: 240  AKRWGCIHTVTKRWFEQSVARRACLNEESYPVQSGSNTLSIVRMTNQHSLEKGIR--NLQ 297

Query: 2012 DKKSTNSQSGPGPI------AADSEATLSQNISSAISDSTVIMKGEEGIEAPPP------ 1869
               S  + S   P+       +D EATLSQN+S   S   V+ K EE   A  P      
Sbjct: 298  GLSSLATASNAEPVFCSRVADSDLEATLSQNMSGTSSYVPVVTKEEENSPAEYPKSDYSA 357

Query: 1868 --------SKIEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRG 1713
                    S    + +  D  VADDS+++D+ LYL+DCRIL+VGF+A+EMRKLVN VR+G
Sbjct: 358  PVSTKGEKSGASTEHDGCDGVVADDSETDDNDLYLADCRILIVGFNASEMRKLVNLVRKG 417

Query: 1712 GGSRYMAFNDRLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKR 1533
            GGSRYM+F ++LTHI+ G P+ENE +ELR   A GVI+VV++ WL+DCDRE KE+PV ++
Sbjct: 418  GGSRYMSFGEKLTHIIAGNPSENEIKELRNLAALGVIHVVKSGWLEDCDRENKEVPVLRK 477

Query: 1532 HVVPDLILPKDSVFSDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPREQT 1377
            H+  DL+LPKD +       I T   RQG + + P S  +H      + C  PS   ++ 
Sbjct: 478  HIAYDLLLPKDPIHCSNGAAITTTIKRQGKSYVHPMSSDEHAWRSRDSGCAMPSYESKEV 537

Query: 1376 EERKTMEAS---------------KQESSMVKKNS--------SNIXXXXXXXXXXXFPL 1266
            E    +  S               K+E  +  ++S        S++           FP 
Sbjct: 538  ENMNDVRTSLGENGVQHQPYASNGKEEFKIPNESSCAVNGRKPSSVFEGRRFCFSASFPA 597

Query: 1265 DRRAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLE 1086
            DRRAEIVEW+ QGGG +V  Q+E N++FT+ECHG++        + TT VS+HWI+SCLE
Sbjct: 598  DRRAEIVEWVNQGGGVVVKDQNETNLHFTIECHGML--RSEKDGAATTFVSSHWIKSCLE 655

Query: 1085 DACMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSK 906
            D C+ DVG HI+YSP+PC++P P F++FR CVSQY+EK+R LLRNLCF +GAKF EKL+K
Sbjct: 656  DGCLLDVGDHILYSPLPCRVPFPAFKSFRLCVSQYDEKERQLLRNLCFTIGAKFVEKLTK 715

Query: 905  KVTHLLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGL 726
            KVTHLLCKFT+GPKYEAACKWG+Q VT EWI ECI+QN +VSA PF PKE+T++DREAG 
Sbjct: 716  KVTHLLCKFTDGPKYEAACKWGIQPVTCEWIYECIKQNKIVSADPFYPKEVTSEDREAGA 775

Query: 725  ATMSQYTTQAARMISGEDVPSQSQGQSQFAMN-SSRTFGKKSTNLSVEAEYPSATNKKRA 549
             T+SQ+ TQA  MISG D  SQ Q Q Q  +N  +  F  ++T    E +YPS  NKK  
Sbjct: 776  CTVSQFPTQAFGMISG-DTTSQPQTQPQELVNVRTEAFAGRNT-AKEEKKYPSRWNKKAR 833

Query: 548  KVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSK 369
                   K  L      +N         K   G    ++GS  VPDVAAAIEDLLE++SK
Sbjct: 834  LFVVEEPKCSLSCSPKESNAFCGASPPEKNLTGST--NEGSSAVPDVAAAIEDLLEQTSK 891

Query: 368  IQDMALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQ 189
            I D     R+  D+ +F+   + + Q    +H+ + +S  W +R EK+D+ +     +  
Sbjct: 892  IHDQKSPSRSECDKELFTSGCNNLAQGHGDNHATLGLSNHWTNRFEKEDETHTHSGDATA 951

Query: 188  GVNEHRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
             V     YD FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 952  NV-----YDHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 988


>gb|KJB80623.1| hypothetical protein B456_013G107700 [Gossypium raimondii]
          Length = 977

 Score =  929 bits (2402), Expect = 0.0
 Identities = 518/998 (51%), Positives = 657/998 (65%), Gaps = 55/998 (5%)
 Frame = -3

Query: 2885 RTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSHDK 2706
            + K+F GSNVF+SRNLV P+ FD +H  LK NGA+VFLCCDPSR+G +D+HVIS   H+K
Sbjct: 5    KAKAFMGSNVFMSRNLVPPEVFDKLHGVLKDNGAQVFLCCDPSRNGPDDFHVISSFDHEK 64

Query: 2705 FEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKL 2526
            FEDL AKGC L+G + VISC  ENRALPK +GF+CCLAMDG+KVLA+GFD  EK KIEKL
Sbjct: 65   FEDLRAKGCNLIGPQCVISCANENRALPK-QGFSCCLAMDGLKVLASGFDMDEKVKIEKL 123

Query: 2525 VTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPHEP 2346
            V AMGGV  T+A+LD  FVI KNVL+ KYKW L+ LKKP++TI WLYQCWSEHR+VP E 
Sbjct: 124  VIAMGGVLHTKASLDVSFVIVKNVLAAKYKWALNVLKKPIVTIQWLYQCWSEHRVVPQES 183

Query: 2345 CRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQ 2166
             RVLPF+GLTI  T I AD RKE+E LI+ NGG+YS +LT+         PEGDKY+VA+
Sbjct: 184  YRVLPFTGLTISVTGIRADERKEIEKLIIQNGGKYSAELTKKF-------PEGDKYKVAR 236

Query: 2165 KWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTNSQS 1986
            +WGH+ I+ + W      R+  L E++Y VQG + S+   +   L  ++ QDK   +S S
Sbjct: 237  RWGHVHIIVRKWFDQCIARRACLNEESYPVQGGSASSKKSVSGSLSAQHSQDKFRASSVS 296

Query: 1985 GPGPIAA---------------DSEATLSQNISSAISDSTVIMKGEEGIEAPPPSKIEDK 1851
                +                 D EA  SQN  S +SD+  I + E+G EAP    ++  
Sbjct: 297  ATSLVVPEFNMSTVPSTGLGDPDLEAAHSQNTPSVLSDAQAIFE-EDGGEAP---NLQPS 352

Query: 1850 EET-LDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLT 1674
             ET LD CVA+DSQSED+ LYLSDC+I LVGF A+EMRKLV  VRRGG SRYM+ N++LT
Sbjct: 353  TETKLDGCVANDSQSEDNDLYLSDCKISLVGFEASEMRKLVTMVRRGGASRYMSCNEKLT 412

Query: 1673 HIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSV 1494
            HIVVG P+E E++E+R   A+GVI+VV+  WL+DCDR+KKE+PV +RHV   L+LPKDS 
Sbjct: 413  HIVVGAPSELEKKEVRSIAASGVIHVVKTSWLEDCDRQKKEIPVHQRHVAYGLLLPKDSA 472

Query: 1493 FSDKA----------------TKIGTRQ----GHNLITPPSVPDHLTQCFRPSMPREQTE 1374
             S +                 T  GT      G +L   P +  +   C + ++   +  
Sbjct: 473  HSVRGAVTGIINSNQSKSSVPTNSGTGMPSSFGKSLDDKPKINMNGGSCLKATVGSSKQG 532

Query: 1373 ERKTMEAS-----KQESSMVKKN-----SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGG 1224
               T+ ++     KQ+   V +N     SS +           FP DRRAEIVEW+ QGG
Sbjct: 533  LLPTINSTSNFWQKQQYDSVVQNPKNGISSAVFKGKTFCFSVSFPEDRRAEIVEWVDQGG 592

Query: 1223 GEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYS 1044
            G++V+ Q + NVNF +ECHG++     ++ SQ T VSTHW+RSCLED C+ DVG HI+YS
Sbjct: 593  GQVVEDQVKKNVNFIIECHGVIPSC--ITDSQITYVSTHWVRSCLEDGCLLDVGRHILYS 650

Query: 1043 PVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPK 864
            P+PC+IP PGF+ FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPK
Sbjct: 651  PLPCQIPFPGFKNFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPK 710

Query: 863  YEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMI 684
            YEAACKWG+Q+VTSEWI EC+RQN VVS  PF PKE+TAQD+EAGL T+SQ+ TQAA+MI
Sbjct: 711  YEAACKWGIQSVTSEWIYECVRQNKVVSLDPFCPKEVTAQDQEAGLCTVSQFPTQAAKMI 770

Query: 683  SGEDVPSQSQGQSQ------FAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKI 522
            +  DVPSQ   Q Q        +      G ++     EAE  S  + KRA+   ++D+ 
Sbjct: 771  A-VDVPSQFTSQPQGLRTQDLGVKMGSITGDRNDGSRDEAE-QSNDHFKRARHLEDDDQN 828

Query: 521  DLLPLDVCANVSSCTMKSIKTSEGGN-IRDDG--SHDVPDVAAAIEDLLEESSKIQDMAL 351
            DLL     + V  C     + S G N +++ G  +  +PDV   I DLLE++SKI D   
Sbjct: 829  DLL----VSRVHLCEPFLNENSTGNNKLKNAGEAAQVLPDVDTVI-DLLEQTSKIHDQKS 883

Query: 350  SGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHR 171
              R   DRSIF  D + + Q+    HS I +S  WL+R  ++D+     SS  + VN   
Sbjct: 884  PERNGCDRSIFLSDCTGLRQDHTDPHSVIGLSRHWLNRNVRKDE----ISSHSRDVNAGS 939

Query: 170  TYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSSMT 57
             Y GFSETQTESQVV YEEDLSGRQM+IDR RTRSSMT
Sbjct: 940  LYGGFSETQTESQVVGYEEDLSGRQMLIDRVRTRSSMT 977


>ref|XP_007019211.1| Topbp1, putative isoform 3 [Theobroma cacao]
            gi|508724539|gb|EOY16436.1| Topbp1, putative isoform 3
            [Theobroma cacao]
          Length = 929

 Score =  928 bits (2398), Expect = 0.0
 Identities = 505/938 (53%), Positives = 650/938 (69%), Gaps = 52/938 (5%)
 Frame = -3

Query: 2894 VMERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPS 2715
            +M +TK+FKGS+VF+SRNLV P+ FD +H  LK +GA+VFLCCDPSR+G +D+HVIS   
Sbjct: 2    MMLKTKAFKGSSVFMSRNLVPPEVFDKLHGVLKDSGAQVFLCCDPSRNGPDDFHVISSID 61

Query: 2714 HDKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKI 2535
            H+KFEDL AKGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KI
Sbjct: 62   HEKFEDLRAKGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKI 120

Query: 2534 EKLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVP 2355
            EKLVTAMGGV  T+A+LD  FV+ KNVL+ KYKW L+ LKKP++T++WLYQCW EHR+VP
Sbjct: 121  EKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVP 180

Query: 2354 HEPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYR 2175
             E  RVLPFSGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+
Sbjct: 181  QESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYK 240

Query: 2174 VAQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTN 1995
            VA++WGH+ IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +
Sbjct: 241  VARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGS 300

Query: 1994 SQSGPGPIAADS---------------EATLSQNISSAISDSTVIMKGEEGIEAPPPSKI 1860
            S S    + +D                EATLSQNI S +SD+ VI+K E+G EAP    +
Sbjct: 301  SLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---L 356

Query: 1859 EDKEET-LDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFND 1683
            +   ET LD CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND
Sbjct: 357  QPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCND 416

Query: 1682 RLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPK 1503
            +LTHIVVGTP+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPK
Sbjct: 417  KLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPK 476

Query: 1502 DSVFSDKATKIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEA 1353
            DSV S K   IG   + Q  + +   S       + D+L    + +   +++ E  T+ +
Sbjct: 477  DSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRS 535

Query: 1352 SKQE-----------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWI 1236
            SKQ                   S+V   KN  SS +           FP DRRAEIVEW+
Sbjct: 536  SKQGVPPTVNSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWV 595

Query: 1235 KQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSH 1056
             QGGGE+VD   + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG H
Sbjct: 596  DQGGGEVVDDHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCH 653

Query: 1055 IIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFT 876
            I+YSP+PC+IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT
Sbjct: 654  ILYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFT 713

Query: 875  NGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQA 696
            +GPKYEAACKWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA
Sbjct: 714  SGPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQA 773

Query: 695  ARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDK 525
             +M+S  D+PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+
Sbjct: 774  VQMMS-VDIPSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQ 829

Query: 524  IDLLP--LDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMAL 351
              LL   + +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SKI D   
Sbjct: 830  NGLLASVVHLCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKIHDQKS 886

Query: 350  SGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSR 237
              R   D+SIFS D + + Q+   SHS I +S  WL+R
Sbjct: 887  PERNGCDKSIFSSDRTGLCQDHTDSHSVIGLSRHWLNR 924


>ref|XP_006345369.1| PREDICTED: DNA topoisomerase 2-binding protein 1-like [Solanum
            tuberosum]
          Length = 990

 Score =  920 bits (2378), Expect = 0.0
 Identities = 495/1005 (49%), Positives = 650/1005 (64%), Gaps = 62/1005 (6%)
 Frame = -3

Query: 2891 MERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSH 2712
            M  TK F G+N F+SRNLV P++FDA+HD+LK NGA+V LCCDPSR+   DYHVIS P H
Sbjct: 1    MMTTKVFNGANAFMSRNLVPPEQFDALHDALKLNGAQVLLCCDPSRNAPTDYHVISSPQH 60

Query: 2711 DKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIE 2532
            +KF DL AKGC L+G + ++SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK +I 
Sbjct: 61   EKFGDLQAKGCNLIGPQCILSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVEIG 119

Query: 2531 KLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPH 2352
            KLV AMGGV QT+A+LD  FVI KNVL+ KYKW  + LKKP++TINWL+QCW EHRLVP 
Sbjct: 120  KLVIAMGGVLQTKASLDVSFVIVKNVLAAKYKWAYNILKKPIVTINWLHQCWKEHRLVPQ 179

Query: 2351 EPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRV 2172
            E  ++LPFSGLTI  TR+ AD RK+ME +I+ NGG+YS +LTR C+HLI D PEGDK++V
Sbjct: 180  ESFKILPFSGLTISVTRVPADERKDMEKIILQNGGKYSPELTRKCSHLICDVPEGDKFKV 239

Query: 2171 AQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQG-------ITMSANHVLKNKLREKNYQ 2013
            A++WG I  VTK W   S  R+  L E++Y VQ        + M+  H L+  +R  N Q
Sbjct: 240  AKRWGCIHTVTKRWFEQSVARRACLNEESYPVQAGSNTLSTVRMTNQHSLEKGIR--NLQ 297

Query: 2012 DKKSTNSQSGPGPI------AADSEATLSQNISSAISDSTVIMKGEEGIEAPPP------ 1869
               S  + S   P+       +D EATLSQN+S+  S + V  K  E   A  P      
Sbjct: 298  GLSSLATASSAEPVFCSRVADSDLEATLSQNMSATSSYAPVFTKEPENSPAEYPKSDYSA 357

Query: 1868 ----------SKIEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVR 1719
                      +  E +    D  VADDS+++D+ LYL+DCRIL+VGF+A+EMRKLVN VR
Sbjct: 358  PVSTKGKKSGASTEQENNGCDGVVADDSETDDNDLYLADCRILIVGFNASEMRKLVNLVR 417

Query: 1718 RGGGSRYMAFNDRLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVS 1539
            +GGGSRYM+F+++LTHI+ G P+ENE +ELR   A GVI+VV++ WL+DCDRE KE+PV 
Sbjct: 418  KGGGSRYMSFSEKLTHIIAGNPSENEIKELRNLAALGVIHVVKSGWLEDCDRENKEVPVL 477

Query: 1538 KRHVVPDLILPKDSVFSDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPRE 1383
            ++H+  DL+LPKD +       I T   RQG + + P S  +       ++C  PS   +
Sbjct: 478  RKHIAYDLLLPKDPIHCSNGAAITTTMKRQGKSYVHPMSSDEQAWRSRDSRCAMPSYENK 537

Query: 1382 QTEERKTMEAS---------------KQESSMVKKNS--------SNIXXXXXXXXXXXF 1272
            + E    +  S               K+E  +  ++S        S++           F
Sbjct: 538  ELENMNDVRTSLGENGVQHQPYASNGKEEFKIPNESSCAVNGRKPSSVFEGRQFCFSASF 597

Query: 1271 PLDRRAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLV--TKAGNVSQSQTTIVSTHWIR 1098
            P DRRAEIVEW+ QGGG +V  Q++ NV+FTVECHG++   KAG    + TT VS+HWI+
Sbjct: 598  PADRRAEIVEWVNQGGGVVVKDQNDTNVHFTVECHGMLRSEKAG----AATTFVSSHWIK 653

Query: 1097 SCLEDACMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTE 918
            SCLED C+ DVG+HI+YSP+PC++P P F++FR CVSQY+EK+R LLRNLCF +GAKF E
Sbjct: 654  SCLEDGCLLDVGNHILYSPLPCRVPFPAFKSFRLCVSQYDEKERQLLRNLCFTIGAKFVE 713

Query: 917  KLSKKVTHLLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDR 738
            KL+KKVTHLLCKFT+GPKYEAACKWG+Q VT EWI ECI QN +VSA PF PKE+T++DR
Sbjct: 714  KLTKKVTHLLCKFTDGPKYEAACKWGIQPVTCEWIYECINQNKIVSADPFYPKEVTSEDR 773

Query: 737  EAGLATMSQYTTQAARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNLSVEAEYPSATNK 558
            EAG  T+SQ+ TQA  MISG+   + SQ   +     +  F  +ST    E +Y S  NK
Sbjct: 774  EAGACTVSQFPTQAFGMISGD---TASQPLQELVNVRTEAFAGRST-AKEEKKYSSRWNK 829

Query: 557  KRAKVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEE 378
            K   +     K   LP     + + C     + +  G+  ++GS  VPDVAAAIEDLLE+
Sbjct: 830  KARLLVVEEPKCS-LPCSPKESNAFCGASPPEKNLTGS-TNEGSSAVPDVAAAIEDLLEQ 887

Query: 377  SSKIQDMALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSS 198
            +SKI D     R+  D+ +F+   + + Q     H+ + +S  W +R EK+D     ++ 
Sbjct: 888  TSKIHDQKSPSRSECDKELFTSGCNNLAQAHGDHHATLGLSNHWTNRFEKED-----ETQ 942

Query: 197  SVQGVNEHRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
            S  G      YD FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 943  SHSGDATANVYDHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 987


>ref|XP_009788828.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X2
            [Nicotiana sylvestris]
          Length = 990

 Score =  916 bits (2367), Expect = 0.0
 Identities = 486/999 (48%), Positives = 639/999 (63%), Gaps = 56/999 (5%)
 Frame = -3

Query: 2891 MERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSH 2712
            M  TK F G++VF+SRNLV P++FDA+HD+LK NGA+VFLCCDPSR+ + DYHVIS P H
Sbjct: 1    MMTTKVFNGASVFMSRNLVPPEQFDALHDALKHNGAQVFLCCDPSRNSSTDYHVISSPHH 60

Query: 2711 DKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIE 2532
            +KF DL AKGC L+G + V+SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK ++ 
Sbjct: 61   EKFGDLQAKGCNLIGPQCVLSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVELG 119

Query: 2531 KLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPH 2352
            KLV+AMGGV  T+A+LD  FVI KNVL+ KYKW ++ LKKP++TINWL QCW EHRLVP 
Sbjct: 120  KLVSAMGGVLHTKASLDVSFVIVKNVLAAKYKWAVNKLKKPIVTINWLQQCWKEHRLVPQ 179

Query: 2351 EPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRV 2172
            E  +VLPFSGLTIC TRI  D R+EME +I+ NGG+YS +LTR C+HLI +APEG+KY+V
Sbjct: 180  ESFKVLPFSGLTICVTRIPIDERREMEKIILQNGGKYSPELTRKCSHLICNAPEGEKYKV 239

Query: 2171 AQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQG--------ITMSANHVLKNKLREKNY 2016
            A++WGHI  VTK W   S  R+  L E++Y VQ         + M+  H L+  +R    
Sbjct: 240  AKRWGHIHTVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSLEKGMRNLQG 299

Query: 2015 QDKKSTNSQSGPGPIAADSEATLSQNISSAISDSTVIMKGEEGI----------EAPPPS 1866
                +T S + P   +  S++ +   +S  + D+ V+ K E  +           AP  +
Sbjct: 300  LSSLATPSNAEPVLCSGASDSYVEATLSQDMPDTPVLTKKEVNLAPAENPKSDYSAPVST 359

Query: 1865 K-------IEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGG 1707
            K       IE ++   D  VADD+Q++D+  YL+DCRIL+VGF+A+EMRKLVN VR+GGG
Sbjct: 360  KNEQSGAPIEQEQNDCDGGVADDTQADDNDFYLADCRILIVGFNASEMRKLVNLVRKGGG 419

Query: 1706 SRYMAFNDRLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHV 1527
            SRYM+F ++LTHI+ G P+ENE +ELR   A GV++VV++ WL DCDREKKE+PV ++H+
Sbjct: 420  SRYMSFGEKLTHIIAGNPSENEIKELRNLAALGVVHVVKSEWLQDCDREKKEVPVLRKHI 479

Query: 1526 VPDLILPKDSVFSDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPREQTEE 1371
              DL+LPKD +         T   RQG +     S  +H      + C  PS   ++ E 
Sbjct: 480  AYDLLLPKDPIHCSNGAGTSTSMKRQGKSYGHTISSDEHAWRGTDSGCAMPSDKNKELEN 539

Query: 1370 RKTMEASKQESSMVK----------------------KNSSNIXXXXXXXXXXXFPLDRR 1257
               +  S +E+ +                        +  S++           FP+DRR
Sbjct: 540  MNDIRTSLRENGVQHQPYSSHHKDEKLLNESGCAVNGRKPSSVFEGRRFCFSASFPVDRR 599

Query: 1256 AEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDAC 1077
            AEIVEW+ QGGG +V+ Q+E NV+FTVECHG  T       +  T VS+HWI+SCLED C
Sbjct: 600  AEIVEWVSQGGGVVVEDQTETNVHFTVECHG--TLCSEKDGAAATFVSSHWIKSCLEDGC 657

Query: 1076 MPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVT 897
            + DVGSHI+YSP+PC++P P F++FRFCVSQY+EK+R LLRNLCF +GAKF EKL+K+VT
Sbjct: 658  LLDVGSHILYSPLPCRVPFPAFQSFRFCVSQYDEKERQLLRNLCFTIGAKFAEKLTKRVT 717

Query: 896  HLLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATM 717
            HLLCKF +GPKYE ACKWG+Q VT EWI ECI+ N +VS  PF PKE+T++DREAG+ T 
Sbjct: 718  HLLCKFISGPKYEVACKWGIQPVTCEWIYECIKLNKIVSPDPFYPKEVTSEDREAGVCTT 777

Query: 716  SQYTTQAARMISGEDVPSQSQGQSQFAMN-SSRTFGKKSTNLSVEAEYPSATNKKRAKVS 540
            SQ+ TQA RM SG D  SQ Q Q Q  +N  +  F  +S     E ++ S  NKK   + 
Sbjct: 778  SQFPTQAVRMTSG-DTSSQPQSQPQELINLRTEAFAGRSI-AKEEMKHSSRWNKKARLMV 835

Query: 539  ANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQD 360
                   L  +    N    T    K   G     +GS  VPDVAAAIEDLLE++SKI D
Sbjct: 836  VEETNCSLTCVSNENNAFCGTNPPEKNMIGST--KEGSSAVPDVAAAIEDLLEQTSKIHD 893

Query: 359  MALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVN 180
                 R   D+ +F+   +I+ Q     H+ + +S  W +R EK+DD +     +   V 
Sbjct: 894  QKSPSRIECDKELFTSGCNILAQGHEDHHTTLGLSNDWTNRFEKKDDSHGHSGDATANV- 952

Query: 179  EHRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
                YD FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 953  ----YDHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 987


>ref|XP_009605009.1| PREDICTED: DNA topoisomerase 2-binding protein 1 [Nicotiana
            tomentosiformis]
          Length = 990

 Score =  914 bits (2363), Expect = 0.0
 Identities = 496/1006 (49%), Positives = 651/1006 (64%), Gaps = 63/1006 (6%)
 Frame = -3

Query: 2891 MERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSH 2712
            M  TK F G+NVF+SRNLV P+ FDA+HD+LK NGA+VFLCCDPSR+ + DYHVIS P H
Sbjct: 1    MMSTKVFNGANVFMSRNLVPPELFDALHDALKHNGAKVFLCCDPSRNSSTDYHVISSPQH 60

Query: 2711 DKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIE 2532
            +KF DL AKGC L+G + V+SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK ++ 
Sbjct: 61   EKFGDLQAKGCNLIGPQCVLSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVELG 119

Query: 2531 KLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPH 2352
            KLV+AMGGV  T+A+LD  FVI KNVL+ KYKW ++ LKKP++TINWL QCW EHRLVP 
Sbjct: 120  KLVSAMGGVLHTKASLDVSFVIVKNVLAAKYKWAVNKLKKPIVTINWLQQCWKEHRLVPQ 179

Query: 2351 EPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRV 2172
            E  +VLPFSGLTIC TRI  D R+EME +I+ NGG+YS +LTR C+HLI +APEG+KY+V
Sbjct: 180  ESFKVLPFSGLTICVTRIPIDERREMEKIILQNGGKYSPELTRKCSHLICNAPEGEKYKV 239

Query: 2171 AQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQG--------ITMSANHVLKNKLREKNY 2016
            A++WGHI  VTK W   S  R+  L E++Y VQ         + M   H L+  +R  N 
Sbjct: 240  AKRWGHIHTVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMPNQHSLEKGMR--NL 297

Query: 2015 QDKKSTNSQSGPGPI----AADS--EATLSQNISSAISDSTVIMKGEEGI---------- 1884
            Q   S  + S   P+    A DS  EATLSQ+    + D+ V+ K EE +          
Sbjct: 298  QGLSSLATPSNAEPVLCSGATDSYVEATLSQD----MPDAPVLTKEEENLAPAENPKSDY 353

Query: 1883 EAPPPSK-------IEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNK 1725
             AP  +K       IE ++   D  VADDSQ++D+  YL+DCRIL+VGF+A+EMRKLVN 
Sbjct: 354  SAPVSTKDEQSGAPIEQEKNDCDGGVADDSQTDDNDFYLADCRILIVGFNASEMRKLVNL 413

Query: 1724 VRRGGGSRYMAFNDRLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELP 1545
            VR+GGGSRYM+F ++LTHI+ G P+E E +ELR   A GVI+VV++ WL DCD EKKE+P
Sbjct: 414  VRKGGGSRYMSFGEKLTHIIAGNPSEFEIKELRNLAALGVIHVVKSGWLQDCDLEKKEVP 473

Query: 1544 VSKRHVVPDLILPKDSVFSDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMP 1389
            V ++H+  DL+LPKD +         T   RQG + +   S  +H      + C  PS  
Sbjct: 474  VLRKHIAYDLLLPKDPIHCSNGAGTSTSMKRQGKSYVHTMSSDEHAWRGTDSGCAMPSDK 533

Query: 1388 REQTEERKTMEASKQESSMVK----------------------KNSSNIXXXXXXXXXXX 1275
             ++ E    +  S +E+ +                        +  S++           
Sbjct: 534  NKELENMNDIRTSLRENGVQHQPYSSNSKDEKLVNESGCAVNGRKPSSVFEGRRFCFSAS 593

Query: 1274 FPLDRRAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLV--TKAGNVSQSQTTIVSTHWI 1101
            FP+DRR EIVEW+ QGGG +V+ Q+E NV+FTVECHG++   K G V+    T VS+HWI
Sbjct: 594  FPVDRRTEIVEWVSQGGGVVVEDQTETNVHFTVECHGMLRSEKDGAVA----TFVSSHWI 649

Query: 1100 RSCLEDACMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFT 921
            +SCLED C+ DVGSH++YSP+PC++P P F++FR CVSQY+EK++ LLRNLCF +GAKF 
Sbjct: 650  KSCLEDGCLLDVGSHVLYSPLPCRVPFPAFQSFRLCVSQYDEKEKQLLRNLCFTIGAKFV 709

Query: 920  EKLSKKVTHLLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQD 741
            EKL+K+VTHLLCKFT+GPKYEAACKWG+Q VT EWI ECI+QN +VS   F PKE+TA+D
Sbjct: 710  EKLTKRVTHLLCKFTSGPKYEAACKWGIQPVTCEWIYECIKQNKIVSPDQFYPKEVTAED 769

Query: 740  REAGLATMSQYTTQAARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNLSVEAEYPSATN 561
            REAG+ TMSQ+ TQA RMIS  D  SQ Q Q Q  +N  RT      +++ E    S+  
Sbjct: 770  REAGVCTMSQFPTQAVRMIS-SDTSSQPQSQPQELIN-LRTEAFAGRSIAKEEMKHSSRW 827

Query: 560  KKRAKVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLE 381
             K+A++    +    L      N + C     + +  G+ ++D S  VPDVAAAIEDLLE
Sbjct: 828  NKKARLLVVEETNCSLTCVSNENNAFCGTNPPEKNMIGSTKEDSS-AVPDVAAAIEDLLE 886

Query: 380  ESSKIQDMALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDS 201
            ++SKI D     R   D+ +F+   + + Q     H+ + +S  W +R EK+DD +    
Sbjct: 887  QTSKIHDQKSPSRIECDKELFTSGCNTLAQGHGDHHATLGLSNHWTNRFEKKDDSHGHSG 946

Query: 200  SSVQGVNEHRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
             +   V     YD FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 947  DATANV-----YDHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 987


>ref|XP_008444199.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X2 [Cucumis
            melo]
          Length = 970

 Score =  911 bits (2354), Expect = 0.0
 Identities = 504/998 (50%), Positives = 656/998 (65%), Gaps = 53/998 (5%)
 Frame = -3

Query: 2891 MERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSH 2712
            M + K F G+NVF+SRNLV P+ FDA+HD+LKQNGAEVFLCCDPSR+G NDYHVIS   H
Sbjct: 1    MLKPKPFAGANVFVSRNLVAPEMFDALHDALKQNGAEVFLCCDPSRNGPNDYHVISSADH 60

Query: 2711 DKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIE 2532
            +KFEDL AKGC LLG + V+SC KE+R LP+ +G+TCCLAMDGVK+LA+GF   EK +I 
Sbjct: 61   EKFEDLRAKGCNLLGPQCVMSCAKEHRPLPQ-QGYTCCLAMDGVKILASGFQEDEKAEIG 119

Query: 2531 KLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPH 2352
            KLV+AMGGV  T+A+LD  FVI KN L+ KYKW L+  KKP+++ +WL QCW EHR+VP 
Sbjct: 120  KLVSAMGGVLYTKASLDVSFVIAKNALAAKYKWALNISKKPIVSFSWLQQCWIEHRVVPQ 179

Query: 2351 EPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRV 2172
            E  RVLPFSGL I  +RI A  RKEME LI+ NGG+YS DLTR CTHLI DAPEGDKY+V
Sbjct: 180  EGYRVLPFSGLNISVSRIPAGERKEMEKLILQNGGRYSADLTRKCTHLICDAPEGDKYKV 239

Query: 2171 AQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTNS 1992
            A+ WG I IVT+ W   S  RK  L E+ Y V G++ ++N + ++ L   N Q+K + N 
Sbjct: 240  ARTWGRINIVTRKWFDQSIARKACLSEELYPVGGVSGTSNKLTRSCLTAHNSQEKVTGNL 299

Query: 1991 QSGPGPIAADS---------------EATLSQNISSAISDSTVIMKGEEGIEAPPPSKIE 1857
            Q+ P    ADS               EATLSQ+ +S  SD++  +  E  +E P  +   
Sbjct: 300  QAAPSSFFADSSFTAVSGPGFSDMDVEATLSQS-TSMFSDASHFI-NEVDVEVPVAT--G 355

Query: 1856 DKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRL 1677
              EE   +C+A+D QSE++ LYLS CRI +VGF A+EMRK+VN + RGGGSRYM FND+L
Sbjct: 356  RNEENTVNCLANDFQSEENDLYLSACRIKVVGFEASEMRKIVNMILRGGGSRYMLFNDKL 415

Query: 1676 THIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDS 1497
            THI+VG  +E E++E+R   A+GV++VVR  WL+DCDR+KKE+P+  RH+  D ++PK S
Sbjct: 416  THIIVGNLSEMEKKEVRDIAASGVVHVVRTNWLEDCDRQKKEIPILGRHMAYDELIPKAS 475

Query: 1496 VFSDKATKIGTRQ---GHNLITPPSVPD---HLTQCFRPSMPREQTEER----------- 1368
              S  +T +  R      + I P  VP+   H++   + SM  E+ EE+           
Sbjct: 476  --SKMSTIVIDRSKVPNVHPIVPSIVPEGNIHVS-TGKTSMTVERIEEKSETKVNGDRKM 532

Query: 1367 ---------------KTMEASKQESSMVKKNSSNIXXXXXXXXXXXFPLDRRAEIVEWIK 1233
                           K+ E   ++  +    SS +           FP DRRAEIVEWI 
Sbjct: 533  KLSQKSQQCVPNGTNKSQEKMARDFMVSNGKSSCVFKGKIFCFSSSFPEDRRAEIVEWIN 592

Query: 1232 QGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHI 1053
            QGGGE+V+   +  V+FTVECHG + ++ +V    +T VS+HW+RSCLED C+     HI
Sbjct: 593  QGGGEVVEDHMKQKVHFTVECHGGIPRSTDV---HSTYVSSHWVRSCLEDGCLWATNGHI 649

Query: 1052 IYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTN 873
            +YSP+PC +PL GFE  RFCVSQY++KDR+LLRNLCFVLGAKF EKL+KKVTHL+CKFT+
Sbjct: 650  LYSPLPCCVPLSGFENIRFCVSQYDDKDRVLLRNLCFVLGAKFVEKLTKKVTHLICKFTD 709

Query: 872  GPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAA 693
            G KYEAACKWG+Q +T+EWI EC+RQ+ +VS   +RPKE+TAQDR AGL T+SQ+ TQAA
Sbjct: 710  GTKYEAACKWGIQCITAEWIYECVRQSKIVSLDLYRPKEVTAQDRAAGLCTVSQFPTQAA 769

Query: 692  RMISGEDVPSQSQGQSQFAMNSS--RTFGKKSTNLSVEA-EYPSATNKKRAKVSANNDKI 522
             MI+ E +       SQF ++S+  R     + N S+EA E  S+T KKR        K 
Sbjct: 770  PMIANESI-------SQFPIHSTIPRDQSAGTNNSSIEAVEQISSTKKKRKLFDEAIQKR 822

Query: 521  DLLPLDVCANVSSCTMKSIK--TSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALS 348
             L  L   +  S C + S K  TS+   +    +  VPDVA+AIEDLLE+++KIQD    
Sbjct: 823  PLF-LGNSSTQSDCNLNSTKQTTSKSSVV----TTHVPDVASAIEDLLEQTTKIQDQKSP 877

Query: 347  GRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDD-GNQCDSSSVQGVNEHR 171
            G+T  D+SIF PD S++ Q+ + +     IS  W  R E+++D  N        G+    
Sbjct: 878  GKTGCDKSIFPPDCSLVGQDHSETSQIGGISNQWSKRAERKEDVSNSTAEDGTVGI---- 933

Query: 170  TYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSSMT 57
             YDGFSETQTESQVV YEEDLSGRQM++D+ RTRSSMT
Sbjct: 934  -YDGFSETQTESQVVGYEEDLSGRQMLLDKVRTRSSMT 970


>ref|XP_009788827.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X1
            [Nicotiana sylvestris]
          Length = 995

 Score =  908 bits (2346), Expect = 0.0
 Identities = 485/1004 (48%), Positives = 639/1004 (63%), Gaps = 61/1004 (6%)
 Frame = -3

Query: 2891 MERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSH 2712
            M  TK F G++VF+SRNLV P++FDA+HD+LK NGA+VFLCCDPSR+ + DYHVIS P H
Sbjct: 1    MMTTKVFNGASVFMSRNLVPPEQFDALHDALKHNGAQVFLCCDPSRNSSTDYHVISSPHH 60

Query: 2711 DKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIE 2532
            +KF DL AKGC L+G + V+SC KE R LP+ +GFTCCLAMDGVK+LA+GF+  EK ++ 
Sbjct: 61   EKFGDLQAKGCNLIGPQCVLSCAKEQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVELG 119

Query: 2531 KLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPH 2352
            KLV+AMGGV  T+A+LD  FVI KNVL+ KYKW ++ LKKP++TINWL QCW EHRLVP 
Sbjct: 120  KLVSAMGGVLHTKASLDVSFVIVKNVLAAKYKWAVNKLKKPIVTINWLQQCWKEHRLVPQ 179

Query: 2351 EPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRV 2172
            E  +VLPFSGLTIC TRI  D R+EME +I+ NGG+YS +LTR C+HLI +APEG+KY+V
Sbjct: 180  ESFKVLPFSGLTICVTRIPIDERREMEKIILQNGGKYSPELTRKCSHLICNAPEGEKYKV 239

Query: 2171 AQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQG--------ITMSANHVLKNKLREKNY 2016
            A++WGHI  VTK W   S  R+  L E++Y VQ         + M+  H L+  +R    
Sbjct: 240  AKRWGHIHTVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSLEKGMRNLQG 299

Query: 2015 QDKKSTNSQSGPGPIAADSEATLSQNISSAISDSTVIMKGEEGI----------EAPPPS 1866
                +T S + P   +  S++ +   +S  + D+ V+ K E  +           AP  +
Sbjct: 300  LSSLATPSNAEPVLCSGASDSYVEATLSQDMPDTPVLTKKEVNLAPAENPKSDYSAPVST 359

Query: 1865 K-------IEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGG 1707
            K       IE ++   D  VADD+Q++D+  YL+DCRIL+VGF+A+EMRKLVN VR+GGG
Sbjct: 360  KNEQSGAPIEQEQNDCDGGVADDTQADDNDFYLADCRILIVGFNASEMRKLVNLVRKGGG 419

Query: 1706 SRYMAFNDRLTHIVVGTPTE-----NERRELRRYTAAGVIYVVRAVWLDDCDREKKELPV 1542
            SRYM+F ++LTHI+ G P+E     +E +ELR   A GV++VV++ WL DCDREKKE+PV
Sbjct: 420  SRYMSFGEKLTHIIAGNPSEKLLSCSEIKELRNLAALGVVHVVKSEWLQDCDREKKEVPV 479

Query: 1541 SKRHVVPDLILPKDSVFSDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPR 1386
             ++H+  DL+LPKD +         T   RQG +     S  +H      + C  PS   
Sbjct: 480  LRKHIAYDLLLPKDPIHCSNGAGTSTSMKRQGKSYGHTISSDEHAWRGTDSGCAMPSDKN 539

Query: 1385 EQTEERKTMEASKQESSMVK----------------------KNSSNIXXXXXXXXXXXF 1272
            ++ E    +  S +E+ +                        +  S++           F
Sbjct: 540  KELENMNDIRTSLRENGVQHQPYSSHHKDEKLLNESGCAVNGRKPSSVFEGRRFCFSASF 599

Query: 1271 PLDRRAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSC 1092
            P+DRRAEIVEW+ QGGG +V+ Q+E NV+FTVECHG  T       +  T VS+HWI+SC
Sbjct: 600  PVDRRAEIVEWVSQGGGVVVEDQTETNVHFTVECHG--TLCSEKDGAAATFVSSHWIKSC 657

Query: 1091 LEDACMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKL 912
            LED C+ DVGSHI+YSP+PC++P P F++FRFCVSQY+EK+R LLRNLCF +GAKF EKL
Sbjct: 658  LEDGCLLDVGSHILYSPLPCRVPFPAFQSFRFCVSQYDEKERQLLRNLCFTIGAKFAEKL 717

Query: 911  SKKVTHLLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREA 732
            +K+VTHLLCKF +GPKYE ACKWG+Q VT EWI ECI+ N +VS  PF PKE+T++DREA
Sbjct: 718  TKRVTHLLCKFISGPKYEVACKWGIQPVTCEWIYECIKLNKIVSPDPFYPKEVTSEDREA 777

Query: 731  GLATMSQYTTQAARMISGEDVPSQSQGQSQFAMN-SSRTFGKKSTNLSVEAEYPSATNKK 555
            G+ T SQ+ TQA RM SG D  SQ Q Q Q  +N  +  F  +S     E ++ S  NKK
Sbjct: 778  GVCTTSQFPTQAVRMTSG-DTSSQPQSQPQELINLRTEAFAGRSI-AKEEMKHSSRWNKK 835

Query: 554  RAKVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEES 375
               +        L  +    N    T    K   G     +GS  VPDVAAAIEDLLE++
Sbjct: 836  ARLMVVEETNCSLTCVSNENNAFCGTNPPEKNMIGST--KEGSSAVPDVAAAIEDLLEQT 893

Query: 374  SKIQDMALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSS 195
            SKI D     R   D+ +F+   +I+ Q     H+ + +S  W +R EK+DD +     +
Sbjct: 894  SKIHDQKSPSRIECDKELFTSGCNILAQGHEDHHTTLGLSNDWTNRFEKKDDSHGHSGDA 953

Query: 194  VQGVNEHRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
               V     YD FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 954  TANV-----YDHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 992


>emb|CDP16447.1| unnamed protein product [Coffea canephora]
          Length = 962

 Score =  903 bits (2334), Expect = 0.0
 Identities = 487/984 (49%), Positives = 642/984 (65%), Gaps = 42/984 (4%)
 Frame = -3

Query: 2882 TKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSHDKF 2703
            TK FKG NVF+SRNLV P+ FD++HD+LK NGA+V LCCDPSR+  ND+HVIS   H+KF
Sbjct: 3    TKVFKGENVFMSRNLVPPELFDSLHDALKLNGAQVLLCCDPSRNAPNDFHVISSADHEKF 62

Query: 2702 EDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLV 2523
            EDL AKGC LLG + V+SC KE+R LPK +GFTCCLAMDGVK+L +GF+  E+ +I KLV
Sbjct: 63   EDLRAKGCNLLGPQCVLSCAKEHRPLPK-QGFTCCLAMDGVKLLTSGFEMDERAEIAKLV 121

Query: 2522 TAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPHEPC 2343
            T+MGGV QT+A++D +FVI KNVL+ KYKW L+ LKKP++TINWL+QCW EHR+VP +  
Sbjct: 122  TSMGGVLQTKASMDVNFVIVKNVLAAKYKWALNVLKKPIVTINWLHQCWREHRVVPQDSF 181

Query: 2342 RVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLI----SDAPEGDKYR 2175
            RV PFSGLT+C +RI AD RK++E LI+ NGG+YS +LTR CTHL+    S APEGDKY+
Sbjct: 182  RVPPFSGLTVCVSRIPADERKQLEQLILQNGGKYSAELTRKCTHLMFLDYSYAPEGDKYK 241

Query: 2174 VAQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTN 1995
            VA++WGHI I+++ W   S  R+  L E++Y VQG +M     +    ++K+  + +   
Sbjct: 242  VAKRWGHIHIISRKWFDQSVARRACLNEESYPVQGSSMKTVRKMAMPSQDKSLGNSQCEA 301

Query: 1994 SQSG-------------PGPIAADSEATLSQNISSAISDSTVIMKGEEGIEAPPPSKIED 1854
            S +G             P P    SEA +S ++SSA  D+    + E+  ++    K   
Sbjct: 302  SSAGTASDPHVRQYAQKPEP---SSEANISHDMSSAFCDAPTFTREEDNGQSAEQLK--- 355

Query: 1853 KEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLT 1674
                +D CVADDSQ+ED  LYLS CRI+LVGF+A  MRKLV+ VRRGGGSRYM+FN++LT
Sbjct: 356  NNSNVDGCVADDSQTEDD-LYLSVCRIMLVGFNADNMRKLVSMVRRGGGSRYMSFNEKLT 414

Query: 1673 HIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSV 1494
            HI+VGTP+E+E +E+R   A GVIYVV++ WL+DCDR+KKE+PV KRH+  DLILPKD++
Sbjct: 415  HIIVGTPSESEIKEVRNLAALGVIYVVKSEWLEDCDRQKKEVPVLKRHMAYDLILPKDTI 474

Query: 1493 FSDKATKIGT---RQGHNLITPPSVPDHLTQCFRPSMPREQTEERK-------------- 1365
             S+K + +     RQG ++   P +PD     +  S      E+RK              
Sbjct: 475  NSNKRSFMAMNEMRQGSSV--QPILPDDHIVKYTNSQSGVSFEKRKEVYSIRNEEMSWVN 532

Query: 1364 TMEASKQESSMVK--------KNSSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVD 1209
            T   +KQ+ S  K        + S+N+           FP D+RAEIVEW+ QGGGE+V+
Sbjct: 533  TGNLAKQQQSTQKSASHDRDNRISANVFAGKLFCFSGSFPADQRAEIVEWVNQGGGEVVE 592

Query: 1208 GQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCK 1029
               E N  F VECHG+V    + S S+   VS+HWIRS L D  + DV SHI+YSP+PC+
Sbjct: 593  NLVEGNTYFIVECHGVVPSETDFSGSK--YVSSHWIRSSLMDGHLLDVSSHILYSPLPCQ 650

Query: 1028 IPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAAC 849
            +P   F+ FRFCVSQY+EK+RLLLRNLCF+LG +F EKL+KKVTHLLCKF +GPKYEAAC
Sbjct: 651  VPFMSFKCFRFCVSQYDEKERLLLRNLCFILGVQFVEKLTKKVTHLLCKFASGPKYEAAC 710

Query: 848  KWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDV 669
            KWG+Q VTSEWI EC++QN VVS  PF PKE T+QDRE G+ TM+QY TQ   +ISG+D 
Sbjct: 711  KWGIQPVTSEWIYECVKQNKVVSPGPFCPKEATSQDRETGVCTMTQYPTQGIGIISGDDA 770

Query: 668  PSQSQGQSQFAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKIDLLPLDVCANV 489
                +   +     +  F KKS     E  YP    KK     A+  K      ++  ++
Sbjct: 771  SQLPRHSQECKSVETEAFTKKSE----EINYPIGCLKKARTFEADKTKCSFSEANLTHSI 826

Query: 488  SSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKIQDMALSGRTISDRSIFSPD 309
               +      +E  +     +  VPDVAAAIEDLLE++SKI D     R+    SIF+ D
Sbjct: 827  CRVSPMEEDVTENAS---KVTTMVPDVAAAIEDLLEQTSKIHDQQSPVRSTCGTSIFTSD 883

Query: 308  HSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSSVQGVNEHRTYDGFSETQTESQV 129
             +++ Q+     SA+ +   W +R +K+D     DS + Q       YDGF+ET TESQV
Sbjct: 884  CTVLGQDRGEPQSALGLPKHWKNRFDKKD-----DSHNPQEDARTNDYDGFTETPTESQV 938

Query: 128  VVYEEDLSGRQMMIDRHRTRSSMT 57
            V Y +DLSGRQM+IDR RTR+SMT
Sbjct: 939  VGYADDLSGRQMIIDRVRTRNSMT 962


>ref|XP_014502699.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X3 [Vigna
            radiata var. radiata]
          Length = 975

 Score =  899 bits (2323), Expect = 0.0
 Identities = 494/986 (50%), Positives = 648/986 (65%), Gaps = 45/986 (4%)
 Frame = -3

Query: 2885 RTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSHDK 2706
            + K+F+G+NVF+SRNLV P+ FDA+HD++K NGA++ LCCDPSR+G +DYH+I+   H+K
Sbjct: 8    KMKAFQGANVFMSRNLVPPEVFDALHDAVKDNGAQLHLCCDPSRNGPDDYHIIASSKHEK 67

Query: 2705 FEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKL 2526
            F+DL +KGCKLLG   V+SC K  R LPK +GFTCCLAMDGVKVLA+GFD +EK KIE+L
Sbjct: 68   FDDLKSKGCKLLGPRCVLSCAKGGRPLPK-QGFTCCLAMDGVKVLASGFDTEEKVKIEEL 126

Query: 2525 VTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPHEP 2346
            V  MGGV  T+ +LD +FVI KNVL+ KYKW L+ LKKP++T  WL QC  EHR+VP E 
Sbjct: 127  VAEMGGVLHTKTSLDLNFVIVKNVLARKYKWALNELKKPIVTYEWLKQCSEEHRVVPQES 186

Query: 2345 CRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQ 2166
             +VLPFSGL IC T I ADVRKEME LI+ NGG+YS +LT+NCTHLIS+AP+GDKY+VA+
Sbjct: 187  YKVLPFSGLKICVTGIPADVRKEMEKLILQNGGKYSAELTKNCTHLISEAPQGDKYKVAK 246

Query: 2165 KWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTNSQS 1986
            +WGHI IV K W   S  R+  L E+ + VQ  ++S++ V ++ L  ++ Q+K     QS
Sbjct: 247  RWGHIHIVIKKWFDQSIARRACLNEEFFPVQHGSVSSHKVTRD-LTMQHSQEKDIGKLQS 305

Query: 1985 GPGPIAADS--------------EATLSQNISSAISDSTVIMKGEEGIEAPPPSKIEDKE 1848
                   DS              EA  S+ +S   SDS   +  +E  +A PP +    E
Sbjct: 306  AASSGTTDSNVQVSCAEFRDRDHEAMPSEFMS---SDSQTRIFAKEA-DAEPPLQTSG-E 360

Query: 1847 ETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHI 1668
              LD+ VADDS+S+D+ LYLS+CRILLVGF A EMRKL+N VR+GGGSRYM+FND+LTHI
Sbjct: 361  LNLDNIVADDSESDDNDLYLSECRILLVGFEALEMRKLINIVRKGGGSRYMSFNDKLTHI 420

Query: 1667 VVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVFS 1488
            VVG PTE E++++R   A GVIYVV+  WL+DCD +KKE+PV +RH+  DL+ PK+S   
Sbjct: 421  VVGNPTEMEKKDVRSLAALGVIYVVKTSWLEDCDHKKKEVPVLRRHIAYDLLQPKESTSM 480

Query: 1487 DKATKIGTRQGHNLITPPSV-PDHLTQ-------------CFRP----SMPREQTEERK- 1365
            D +      Q  + +   +V P+ L +              FR     +M + Q  + K 
Sbjct: 481  DHSKSSSCHQSSHQVDFENVKPESLEKRKEQIKDMDINGHSFRKANCRTMLQNQLPDNKL 540

Query: 1364 -TMEASKQESSMVKKNSSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDGQSEFNV 1188
             T   S+ + S+  + S+N+           FP ++R EIV+WI QGGGE++ GQ+E  V
Sbjct: 541  STQGMSQHDFSVQYEKSANVFRGKLFCFSNLFPEEKRGEIVQWISQGGGEVISGQAEQIV 600

Query: 1187 NFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKIPLPGFE 1008
            ++TVECHG+         S++  VS+HWIRSCLE   + DVGSHI+YSP+PC +PLPGFE
Sbjct: 601  HYTVECHGVTPML--TGDSKSLSVSSHWIRSCLEAGSLLDVGSHILYSPLPCHVPLPGFE 658

Query: 1007 AFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACKWGMQTV 828
             FRFCVSQYEEKDR LLRNLCFVLGAKF EKL KKVTHLLCKFTNGPKY+ A KWG+Q+V
Sbjct: 659  RFRFCVSQYEEKDRNLLRNLCFVLGAKFGEKLHKKVTHLLCKFTNGPKYDGARKWGIQSV 718

Query: 827  TSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMISGEDVPSQSQGQ 648
            T EWI EC++QN VV+   F PKE+TAQDREAGL T+SQ+ TQAA+MIS  D+PSQ   Q
Sbjct: 719  TCEWIFECVKQNGVVAVDQFLPKEVTAQDREAGLCTVSQFPTQAAQMIS--DMPSQLSSQ 776

Query: 647  SQFAMN-SSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKIDLLPLDVCANVSSCTMK 471
            SQ     + +  G    N     + PS  +KK A++       + +P    A+ S     
Sbjct: 777  SQILRGITDKNVGCGVGNHETNFKKPSVYSKK-ARLVEEPCLSNKMP---SASNSGIHAY 832

Query: 470  SIKTSEGGNIRDDGS--HDVPDVAAAIEDLLEESSKIQDMALSGRTISDRSIFSPDHSII 297
                SE   + D G     VPDVAAAIEDLLE++SK+        T  +R I+  D S++
Sbjct: 833  GKNFSEDNTLIDGGEVCRTVPDVAAAIEDLLEQTSKMHGQRSPAHTGCERGIYPSDLSVL 892

Query: 296  TQNPATSHSAIQISTSWLS--------RKEKQDDGNQCDSSSVQGVNEHRTYDGFSETQT 141
             ++ +  H+   +S  WL+        R ++++D  +       G+     YDGFSETQT
Sbjct: 893  GEDNSNPHTVFGLSKHWLNSTESIYSYRNDRKEDDGEASQDRPAGI-----YDGFSETQT 947

Query: 140  ESQVVVYEEDLSGRQMMIDRHRTRSS 63
            ESQVV YEEDLSGRQ +ID++RTRSS
Sbjct: 948  ESQVVSYEEDLSGRQSLIDKYRTRSS 973


>ref|XP_007019213.1| Topbp1, putative isoform 5 [Theobroma cacao]
            gi|508724541|gb|EOY16438.1| Topbp1, putative isoform 5
            [Theobroma cacao]
          Length = 894

 Score =  899 bits (2322), Expect = 0.0
 Identities = 487/895 (54%), Positives = 627/895 (70%), Gaps = 52/895 (5%)
 Frame = -3

Query: 2894 VMERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPS 2715
            +M +TK+FKGS+VF+SRNLV P+ FD +H  LK +GA+VFLCCDPSR+G +D+HVIS   
Sbjct: 2    MMLKTKAFKGSSVFMSRNLVPPEVFDKLHGVLKDSGAQVFLCCDPSRNGPDDFHVISSID 61

Query: 2714 HDKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKI 2535
            H+KFEDL AKGC LLG + V+SC KENRALPK +GFTCCLAMDG+KVLA+GFD  EK KI
Sbjct: 62   HEKFEDLRAKGCNLLGPQCVLSCAKENRALPK-QGFTCCLAMDGLKVLASGFDMDEKVKI 120

Query: 2534 EKLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVP 2355
            EKLVTAMGGV  T+A+LD  FV+ KNVL+ KYKW L+ LKKP++T++WLYQCW EHR+VP
Sbjct: 121  EKLVTAMGGVLHTKASLDVSFVVVKNVLAAKYKWALNVLKKPIVTLHWLYQCWGEHRVVP 180

Query: 2354 HEPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYR 2175
             E  RVLPFSGLTIC TRI AD RKE+E LI+ NGG+YS +LT+ CTHLI DAPEGDKY+
Sbjct: 181  QESYRVLPFSGLTICVTRIPADERKEIEKLIIQNGGKYSAELTKKCTHLICDAPEGDKYK 240

Query: 2174 VAQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTN 1995
            VA++WGH+ IV + W   S  R+  L E++Y VQG   S+   +   L  ++ QDK   +
Sbjct: 241  VARRWGHVHIVVRKWFDQSIARRACLNEESYPVQGGCSSSKKNVSGSLSTQHSQDKFRGS 300

Query: 1994 SQSGPGPIAADS---------------EATLSQNISSAISDSTVIMKGEEGIEAPPPSKI 1860
            S S    + +D                EATLSQNI S +SD+ VI+K E+G EAP    +
Sbjct: 301  SLSATSLMISDFNLSTVPPTGVGDPDLEATLSQNIPSMVSDAQVIVK-EDGGEAPT---L 356

Query: 1859 EDKEET-LDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFND 1683
            +   ET LD CVA+DS+SED+ LYLSDCRI LVGF A+EMRKLV  VRRGGGSRYM+ ND
Sbjct: 357  QPSNETKLDGCVANDSESEDNDLYLSDCRISLVGFEASEMRKLVMMVRRGGGSRYMSCND 416

Query: 1682 RLTHIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPK 1503
            +LTHIVVGTP+E E++E+R + A+GV+ VV++ WL+DCDR+KKE+PV +RH+  DL+LPK
Sbjct: 417  KLTHIVVGTPSEVEKKEVRSFAASGVMQVVKSNWLEDCDRQKKEIPVQQRHIAYDLLLPK 476

Query: 1502 DSVFSDKATKIG---TRQGHNLITPPS-------VPDHLTQCFRPSMPREQTEERKTMEA 1353
            DSV S K   IG   + Q  + +   S       + D+L    + +   +++ E  T+ +
Sbjct: 477  DSVQSVKGAVIGMVSSNQSKSSVLANSGTGMSSFLGDNLDDKTKINRNGDKSLEA-TVRS 535

Query: 1352 SKQE-----------------SSMVK--KN--SSNIXXXXXXXXXXXFPLDRRAEIVEWI 1236
            SKQ                   S+V   KN  SS +           FP DRRAEIVEW+
Sbjct: 536  SKQGVPPTVNSTNNGWQKQHCGSIVLNLKNGMSSTVFKGKIFCFSNSFPEDRRAEIVEWV 595

Query: 1235 KQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSH 1056
             QGGGE+VD   + +VNF +ECHG+++++  +  SQ T VSTHW+RSCLED C+ DVG H
Sbjct: 596  DQGGGEVVDDHVKQSVNFIIECHGVISRS--IIDSQITYVSTHWVRSCLEDGCLLDVGCH 653

Query: 1055 IIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFT 876
            I+YSP+PC+IP PGF++FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT
Sbjct: 654  ILYSPLPCQIPFPGFKSFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFT 713

Query: 875  NGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQA 696
            +GPKYEAACKWG+ +VT+EWI EC+ QN VVS  PF PKE+TAQDREAGL T+SQ+ TQA
Sbjct: 714  SGPKYEAACKWGIYSVTAEWIYECVSQNKVVSLDPFFPKEVTAQDREAGLCTVSQFPTQA 773

Query: 695  ARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNL---SVEAEYPSATNKKRAKVSANNDK 525
             +M+S  D+PSQ   QSQ     ++T G K  ++     EAE  S  + KRA+    +D+
Sbjct: 774  VQMMS-VDIPSQFMTQSQDL--RTQTLGGKIESIIGGRDEAE-QSNVHLKRARCMEEDDQ 829

Query: 524  IDLLP--LDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEESSKI 366
              LL   + +C  V +   ++   +    I  + +  +PDVAAAIEDLLE++SK+
Sbjct: 830  NGLLASVVHLCEPVLN---ENSTENNKSKIVGEAAQVLPDVAAAIEDLLEQTSKV 881


>ref|XP_012464227.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X2
            [Gossypium raimondii]
          Length = 937

 Score =  892 bits (2305), Expect = 0.0
 Identities = 486/943 (51%), Positives = 623/943 (66%), Gaps = 55/943 (5%)
 Frame = -3

Query: 2885 RTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSHDK 2706
            + K+F GSNVF+SRNLV P+ FD +H  LK NGA+VFLCCDPSR+G +D+HVIS   H+K
Sbjct: 6    KAKAFMGSNVFMSRNLVPPEVFDKLHGVLKDNGAQVFLCCDPSRNGPDDFHVISSFDHEK 65

Query: 2705 FEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKL 2526
            FEDL AKGC L+G + VISC  ENRALPK +GF+CCLAMDG+KVLA+GFD  EK KIEKL
Sbjct: 66   FEDLRAKGCNLIGPQCVISCANENRALPK-QGFSCCLAMDGLKVLASGFDMDEKVKIEKL 124

Query: 2525 VTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPHEP 2346
            V AMGGV  T+A+LD  FVI KNVL+ KYKW L+ LKKP++TI WLYQCWSEHR+VP E 
Sbjct: 125  VIAMGGVLHTKASLDVSFVIVKNVLAAKYKWALNVLKKPIVTIQWLYQCWSEHRVVPQES 184

Query: 2345 CRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQ 2166
             RVLPF+GLTI  T I AD RKE+E LI+ NGG+YS +LT+ CTHLI D PEGDKY+VA+
Sbjct: 185  YRVLPFTGLTISVTGIRADERKEIEKLIIQNGGKYSAELTKKCTHLICDVPEGDKYKVAR 244

Query: 2165 KWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTNSQS 1986
            +WGH+ I+ + W      R+  L E++Y VQG + S+   +   L  ++ QDK   +S S
Sbjct: 245  RWGHVHIIVRKWFDQCIARRACLNEESYPVQGGSASSKKSVSGSLSAQHSQDKFRASSVS 304

Query: 1985 GPGPIA---------------ADSEATLSQNISSAISDSTVIMKGEEGIEAPPPSKIEDK 1851
                +                 D EA  SQN  S +SD+  I + E+G EAP    ++  
Sbjct: 305  ATSLVVPEFNMSTVPSTGLGDPDLEAAHSQNTPSVLSDAQAIFE-EDGGEAP---NLQPS 360

Query: 1850 EET-LDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLT 1674
             ET LD CVA+DSQSED+ LYLSDC+I LVGF A+EMRKLV  VRRGG SRYM+ N++LT
Sbjct: 361  TETKLDGCVANDSQSEDNDLYLSDCKISLVGFEASEMRKLVTMVRRGGASRYMSCNEKLT 420

Query: 1673 HIVVGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSV 1494
            HIVVG P+E E++E+R   A+GVI+VV+  WL+DCDR+KKE+PV +RHV   L+LPKDS 
Sbjct: 421  HIVVGAPSELEKKEVRSIAASGVIHVVKTSWLEDCDRQKKEIPVHQRHVAYGLLLPKDSA 480

Query: 1493 FS--------------------DKATKIGTRQGHNLITPPSVPDHLTQCFRPSMPREQTE 1374
             S                    +  T + +  G +L   P +  +   C + ++   +  
Sbjct: 481  HSVRGAVTGIINSNQSKSSVPTNSGTGMPSSFGKSLDDKPKINMNGGSCLKATVGSSKQG 540

Query: 1373 ERKTMEAS-----KQESSMVKKN-----SSNIXXXXXXXXXXXFPLDRRAEIVEWIKQGG 1224
               T+ ++     KQ+   V +N     SS +           FP DRRAEIVEW+ QGG
Sbjct: 541  LLPTINSTSNFWQKQQYDSVVQNPKNGISSAVFKGKTFCFSVSFPEDRRAEIVEWVDQGG 600

Query: 1223 GEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSCLEDACMPDVGSHIIYS 1044
            G++V+ Q + NVNF +ECHG++     ++ SQ T VSTHW+RSCLED C+ DVG HI+YS
Sbjct: 601  GQVVEDQVKKNVNFIIECHGVIPSC--ITDSQITYVSTHWVRSCLEDGCLLDVGRHILYS 658

Query: 1043 PVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKLSKKVTHLLCKFTNGPK 864
            P+PC+IP PGF+ FRFCVSQYEEKDRLLLRNLCF+LGAKF EKL+KKVTHLLCKFT+GPK
Sbjct: 659  PLPCQIPFPGFKNFRFCVSQYEEKDRLLLRNLCFILGAKFVEKLTKKVTHLLCKFTSGPK 718

Query: 863  YEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREAGLATMSQYTTQAARMI 684
            YEAACKWG+Q+VTSEWI EC+RQN VVS  PF PKE+TAQD+EAGL T+SQ+ TQAA+MI
Sbjct: 719  YEAACKWGIQSVTSEWIYECVRQNKVVSLDPFCPKEVTAQDQEAGLCTVSQFPTQAAKMI 778

Query: 683  SGEDVPSQSQGQSQ------FAMNSSRTFGKKSTNLSVEAEYPSATNKKRAKVSANNDKI 522
            +  DVPSQ   Q Q        +      G ++     EAE  S  + KRA+   ++D+ 
Sbjct: 779  A-VDVPSQFTSQPQGLRTQDLGVKMGSITGDRNDGSRDEAE-QSNDHFKRARHLEDDDQN 836

Query: 521  DLLPLDVCANVSSCTMKSIKTSEGGN-IRDDG--SHDVPDVAAAIEDLLEESSKIQDMAL 351
            DLL     + V  C     + S G N +++ G  +  +PDV   I DLLE++SKI D   
Sbjct: 837  DLL----VSRVHLCEPFLNENSTGNNKLKNAGEAAQVLPDVDTVI-DLLEQTSKIHDQKS 891

Query: 350  SGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQD 222
              R   DRSIF  D + + Q+    HS I +S  WL+RK  Q+
Sbjct: 892  PERNGCDRSIFLSDCTGLRQDHTDPHSVIGLSRHWLNRKLNQE 934


>ref|XP_009788829.1| PREDICTED: DNA topoisomerase 2-binding protein 1 isoform X3
            [Nicotiana sylvestris]
          Length = 985

 Score =  888 bits (2295), Expect = 0.0
 Identities = 480/1004 (47%), Positives = 632/1004 (62%), Gaps = 61/1004 (6%)
 Frame = -3

Query: 2891 MERTKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSH 2712
            M  TK F G++VF+SRNLV P++FDA+HD+LK NGA+VFLCCDPSR+ + DYHVIS P H
Sbjct: 1    MMTTKVFNGASVFMSRNLVPPEQFDALHDALKHNGAQVFLCCDPSRNSSTDYHVISSPHH 60

Query: 2711 DKFEDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIE 2532
            +KF DL AKGC L+          E R LP+ +GFTCCLAMDGVK+LA+GF+  EK ++ 
Sbjct: 61   EKFGDLQAKGCNLI----------EQRPLPQ-QGFTCCLAMDGVKILASGFEMDEKVELG 109

Query: 2531 KLVTAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPH 2352
            KLV+AMGGV  T+A+LD  FVI KNVL+ KYKW ++ LKKP++TINWL QCW EHRLVP 
Sbjct: 110  KLVSAMGGVLHTKASLDVSFVIVKNVLAAKYKWAVNKLKKPIVTINWLQQCWKEHRLVPQ 169

Query: 2351 EPCRVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRV 2172
            E  +VLPFSGLTIC TRI  D R+EME +I+ NGG+YS +LTR C+HLI +APEG+KY+V
Sbjct: 170  ESFKVLPFSGLTICVTRIPIDERREMEKIILQNGGKYSPELTRKCSHLICNAPEGEKYKV 229

Query: 2171 AQKWGHIRIVTKDWLRDSFNRKVYLPEDAYLVQG--------ITMSANHVLKNKLREKNY 2016
            A++WGHI  VTK W   S  R+  L E++Y VQ         + M+  H L+  +R    
Sbjct: 230  AKRWGHIHTVTKRWFDQSVARRACLDEESYPVQAGSPNTMTTLRMTNQHSLEKGMRNLQG 289

Query: 2015 QDKKSTNSQSGPGPIAADSEATLSQNISSAISDSTVIMKGEEGI----------EAPPPS 1866
                +T S + P   +  S++ +   +S  + D+ V+ K E  +           AP  +
Sbjct: 290  LSSLATPSNAEPVLCSGASDSYVEATLSQDMPDTPVLTKKEVNLAPAENPKSDYSAPVST 349

Query: 1865 K-------IEDKEETLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGG 1707
            K       IE ++   D  VADD+Q++D+  YL+DCRIL+VGF+A+EMRKLVN VR+GGG
Sbjct: 350  KNEQSGAPIEQEQNDCDGGVADDTQADDNDFYLADCRILIVGFNASEMRKLVNLVRKGGG 409

Query: 1706 SRYMAFNDRLTHIVVGTPTE-----NERRELRRYTAAGVIYVVRAVWLDDCDREKKELPV 1542
            SRYM+F ++LTHI+ G P+E     +E +ELR   A GV++VV++ WL DCDREKKE+PV
Sbjct: 410  SRYMSFGEKLTHIIAGNPSEKLLSCSEIKELRNLAALGVVHVVKSEWLQDCDREKKEVPV 469

Query: 1541 SKRHVVPDLILPKDSVFSDKATKIGT---RQGHNLITPPSVPDHL-----TQCFRPSMPR 1386
             ++H+  DL+LPKD +         T   RQG +     S  +H      + C  PS   
Sbjct: 470  LRKHIAYDLLLPKDPIHCSNGAGTSTSMKRQGKSYGHTISSDEHAWRGTDSGCAMPSDKN 529

Query: 1385 EQTEERKTMEASKQESSMVK----------------------KNSSNIXXXXXXXXXXXF 1272
            ++ E    +  S +E+ +                        +  S++           F
Sbjct: 530  KELENMNDIRTSLRENGVQHQPYSSHHKDEKLLNESGCAVNGRKPSSVFEGRRFCFSASF 589

Query: 1271 PLDRRAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQTTIVSTHWIRSC 1092
            P+DRRAEIVEW+ QGGG +V+ Q+E NV+FTVECHG  T       +  T VS+HWI+SC
Sbjct: 590  PVDRRAEIVEWVSQGGGVVVEDQTETNVHFTVECHG--TLCSEKDGAAATFVSSHWIKSC 647

Query: 1091 LEDACMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLCFVLGAKFTEKL 912
            LED C+ DVGSHI+YSP+PC++P P F++FRFCVSQY+EK+R LLRNLCF +GAKF EKL
Sbjct: 648  LEDGCLLDVGSHILYSPLPCRVPFPAFQSFRFCVSQYDEKERQLLRNLCFTIGAKFAEKL 707

Query: 911  SKKVTHLLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFRPKEMTAQDREA 732
            +K+VTHLLCKF +GPKYE ACKWG+Q VT EWI ECI+ N +VS  PF PKE+T++DREA
Sbjct: 708  TKRVTHLLCKFISGPKYEVACKWGIQPVTCEWIYECIKLNKIVSPDPFYPKEVTSEDREA 767

Query: 731  GLATMSQYTTQAARMISGEDVPSQSQGQSQFAMN-SSRTFGKKSTNLSVEAEYPSATNKK 555
            G+ T SQ+ TQA RM SG D  SQ Q Q Q  +N  +  F  +S     E ++ S  NKK
Sbjct: 768  GVCTTSQFPTQAVRMTSG-DTSSQPQSQPQELINLRTEAFAGRSI-AKEEMKHSSRWNKK 825

Query: 554  RAKVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVAAAIEDLLEES 375
               +        L  +    N    T    K   G     +GS  VPDVAAAIEDLLE++
Sbjct: 826  ARLMVVEETNCSLTCVSNENNAFCGTNPPEKNMIGST--KEGSSAVPDVAAAIEDLLEQT 883

Query: 374  SKIQDMALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQDDGNQCDSSS 195
            SKI D     R   D+ +F+   +I+ Q     H+ + +S  W +R EK+DD +     +
Sbjct: 884  SKIHDQKSPSRIECDKELFTSGCNILAQGHEDHHTTLGLSNDWTNRFEKKDDSHGHSGDA 943

Query: 194  VQGVNEHRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSS 63
               V     YD FSETQT+SQVV Y EDLSGRQM+IDR RTRSS
Sbjct: 944  TANV-----YDHFSETQTDSQVVGYAEDLSGRQMIIDRVRTRSS 982


>ref|XP_011091797.1| PREDICTED: DNA topoisomerase 2-binding protein 1-A isoform X2
            [Sesamum indicum]
          Length = 937

 Score =  881 bits (2276), Expect = 0.0
 Identities = 476/955 (49%), Positives = 616/955 (64%), Gaps = 14/955 (1%)
 Frame = -3

Query: 2882 TKSFKGSNVFLSRNLVLPDKFDAVHDSLKQNGAEVFLCCDPSRSGTNDYHVISGPSHDKF 2703
            TK FKG+NVF+SRNLV P+ FDA+HD+LK NGA+V LCCDPSR+G NDYHVI+   H+KF
Sbjct: 3    TKVFKGANVFMSRNLVPPELFDALHDALKLNGAQVLLCCDPSRNGPNDYHVIASHDHEKF 62

Query: 2702 EDLLAKGCKLLGTELVISCGKENRALPKNKGFTCCLAMDGVKVLATGFDNKEKGKIEKLV 2523
            EDL AKGCKL+G + V+SC KE+R LP N+GFTCCLAMDGV +LA+GF+  EK +I K+V
Sbjct: 63   EDLRAKGCKLIGPQCVLSCAKEHRVLP-NQGFTCCLAMDGVNILASGFEKDEKAEIAKMV 121

Query: 2522 TAMGGVFQTRAALDTDFVICKNVLSGKYKWGLHTLKKPVITINWLYQCWSEHRLVPHEPC 2343
            TAMGGV  T+A+ D  FVI KNVL+ KYKW L+ LKKP++T NWL QCW EHR+VP +  
Sbjct: 122  TAMGGVLVTKASSDVSFVIVKNVLAQKYKWALNNLKKPIVTTNWLLQCWKEHRVVPQDCY 181

Query: 2342 RVLPFSGLTICFTRIAADVRKEMENLIVHNGGQYSGDLTRNCTHLISDAPEGDKYRVAQK 2163
            RVLPFSGLTIC + I AD RKEME L++ NGG+YS +LT+ CTHL+ DAPEGDKY+VA++
Sbjct: 182  RVLPFSGLTICVSGIPADERKEMEKLVMQNGGKYSAELTKRCTHLVCDAPEGDKYKVAKR 241

Query: 2162 WGHIRIVTKDWLRDSFNRKVYLPEDAYLVQGITMSANHVLKNKLREKNYQDKKSTNSQ-- 1989
            WGHI IVT+ W   S  R+  L E++Y VQG T+S+   LK    E++ Q K   NSQ  
Sbjct: 242  WGHIYIVTRKWFHQSVARRACLSEESYPVQGSTISSLSTLKTV--EQHSQGKVIRNSQHT 299

Query: 1988 SGPGPIAADSEATLS------------QNISSAISDSTVIMKGEEGIEAPPPSKIEDKEE 1845
            S     A+DSE   S             NI  A  ++  + K +      PP+ ++  + 
Sbjct: 300  SSSMATASDSETNFSAQDMGPDFENPLPNIYPAFFEAPSLPKEDN----DPPADMQKNDP 355

Query: 1844 TLDSCVADDSQSEDSGLYLSDCRILLVGFHAAEMRKLVNKVRRGGGSRYMAFNDRLTHIV 1665
                C+ADDSQSED  LYLS+CRILLVGF A+E+RKLV+ VRRGGGSRYM+F+++LTH++
Sbjct: 356  NFARCIADDSQSEDDDLYLSECRILLVGFEASELRKLVDMVRRGGGSRYMSFSEKLTHVI 415

Query: 1664 VGTPTENERRELRRYTAAGVIYVVRAVWLDDCDREKKELPVSKRHVVPDLILPKDSVFSD 1485
            VG P+E E +E+R   A GVIYVV+  WL++C  +KKE+PV K H+  DL+LPKD V  +
Sbjct: 416  VGKPSELEIKEVRSVAAFGVIYVVKTAWLEECTFKKKEVPVLKSHIAYDLLLPKDPVIFN 475

Query: 1484 KATKIGTRQGHNLITPPSVPDHLTQCFRPSMPREQTEERKTMEASKQESSMVKKNSSNIX 1305
            KAT         + +  S P         S   E   E    +     S+     SS + 
Sbjct: 476  KATATNMNSAKQMKSSASQPMDDNILENKSSQCEVVIEEAKPKVQSGVSNGKHMKSSAVF 535

Query: 1304 XXXXXXXXXXFPLDRRAEIVEWIKQGGGEIVDGQSEFNVNFTVECHGLVTKAGNVSQSQT 1125
                      FP ++R EIV W+ +GGGE++  Q   NV+FTVE HG+          ++
Sbjct: 536  KGKLFGFSSTFPEEQRPEIVLWVHEGGGEVIVDQQVNNVHFTVERHGVPHLTHTF---RS 592

Query: 1124 TIVSTHWIRSCLEDACMPDVGSHIIYSPVPCKIPLPGFEAFRFCVSQYEEKDRLLLRNLC 945
            T V+THWI SCL+D C+ DV SHI+YSP+ C+IPLPGFE FR CVS+Y+ ++R LLRNLC
Sbjct: 593  TYVTTHWIHSCLQDGCLLDVSSHILYSPLTCQIPLPGFEGFRLCVSRYDMRERQLLRNLC 652

Query: 944  FVLGAKFTEKLSKKVTHLLCKFTNGPKYEAACKWGMQTVTSEWISECIRQNAVVSAHPFR 765
            +VLG KF EKL+KKVTHLLCKF +G K+EAAC+WG+  VT+EWI EC  +N VV    F 
Sbjct: 653  YVLGVKFVEKLTKKVTHLLCKFADGDKFEAACRWGIHVVTAEWIYECAMKNKVVDLKGFY 712

Query: 764  PKEMTAQDREAGLATMSQYTTQAARMISGEDVPSQSQGQSQFAMNSSRTFGKKSTNLSVE 585
            PKE+T+QDREAGL  +SQY TQ+ RM SG+D  SQ   Q Q   N  R     +  ++  
Sbjct: 713  PKELTSQDREAGLYFVSQYPTQSVRMTSGDDA-SQCLSQLQDQSNMQRV--ASTGCMARY 769

Query: 584  AEYPSATNKKRAKVSANNDKIDLLPLDVCANVSSCTMKSIKTSEGGNIRDDGSHDVPDVA 405
             +  S+   KRA++   ND I   PL   +   +   +   T             VPDVA
Sbjct: 770  KDNDSSNGSKRARL-LGNDSIK-HPLSFVSAADNSVNRKNPTENNVTECTREPSVVPDVA 827

Query: 404  AAIEDLLEESSKIQDMALSGRTISDRSIFSPDHSIITQNPATSHSAIQISTSWLSRKEKQ 225
            AAIEDLLE++SKIQD      +    +  S + +++ Q  A   S    S  W++R EK+
Sbjct: 828  AAIEDLLEQTSKIQDRKSQETSGCHENFLSSNSTMLGQRHADGQSDPGPSKHWMNRLEKR 887

Query: 224  DDGNQCDSSSVQGVNEHRTYDGFSETQTESQVVVYEEDLSGRQMMIDRHRTRSSM 60
            DD    D+++         YDGFSETQT+SQVV YEEDLSGRQM+IDR RTRSSM
Sbjct: 888  DDNPSADAAA------RGFYDGFSETQTDSQVVGYEEDLSGRQMIIDRVRTRSSM 936