BLASTX nr result
ID: Papaver27_contig00037500
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Papaver27_contig00037500
(2113 letters)
Database: ./nr
38,876,450 sequences; 13,856,398,315 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas ... 115 6e-23
ref|XP_804789.1| R27-2 protein [Trypanosoma cruzi strain CL Bren... 110 3e-21
ref|XP_808187.1| myosin heavy chain [Trypanosoma cruzi strain CL... 109 4e-21
ref|XP_001659192.1| myosin heavy chain, nonmuscle or smooth musc... 107 3e-20
ref|XP_001659191.1| myosin heavy chain, nonmuscle or smooth musc... 107 3e-20
ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas ... 106 5e-20
ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeb... 105 8e-20
ref|XP_001582797.1| viral A-type inclusion protein [Trichomonas ... 103 3e-19
ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas ... 103 3e-19
ref|XP_001319569.1| viral A-type inclusion protein [Trichomonas ... 101 1e-18
gb|ETN62597.1| myosin heavy chain, nonmuscle or smooth muscle [A... 101 2e-18
ref|XP_005159743.1| PREDICTED: titin isoform X6 [Danio rerio] 101 2e-18
ref|XP_005159742.1| PREDICTED: titin isoform X5 [Danio rerio] 101 2e-18
ref|XP_005159740.1| PREDICTED: titin isoform X3 [Danio rerio] 101 2e-18
ref|XP_005159739.1| PREDICTED: titin isoform X2 [Danio rerio] 101 2e-18
ref|XP_005159738.1| PREDICTED: titin isoform X1 [Danio rerio] 101 2e-18
ref|XP_685984.6| PREDICTED: titin isoform X7 [Danio rerio] 101 2e-18
ref|XP_006560777.1| PREDICTED: sporulation-specific protein 15 i... 100 2e-18
ref|XP_006560776.1| PREDICTED: sporulation-specific protein 15 i... 100 2e-18
gb|EMD48416.1| viral Atype inclusion protein repeat-containing p... 100 3e-18
>ref|XP_001318162.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121900914|gb|EAY05939.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 5296
Score = 115 bits (289), Expect = 6e-23
Identities = 123/516 (23%), Positives = 228/516 (44%), Gaps = 18/516 (3%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E+K+ EA D+L ++ KK E K+ +E K+A EAAK D+L
Sbjct: 4266 EDKLKQAEAEKKATEDKLRETENAKKETEEKLAKTEEEKKQVEDKLAATEAAKKETEDKL 4325
Query: 191 ERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLE 370
++ +D+ A K + + +++ ED + + E
Sbjct: 4326 KQTEDEKKATEDKLANVEAEKSDIEQAKKETEDKLKQTEEEKAAVEAEKKATEDKLHETE 4385
Query: 371 VNILILHEELQKEKDDKTALIK-------DLVAAEPGKRTVNEIVSHLESKSRSLKEHFL 529
++L++ +D+K A+ + L E K+ + E++ + L E F
Sbjct: 4386 EAKKETEDKLKQTEDEKAAVEQAKKETEDKLKQTEEEKKATENKLEESEAEKKELGERF- 4444
Query: 530 REEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE----KTVLE 697
E E+ S+L + + ++EL+ K+ KS L + EAEK+ E KT +E
Sbjct: 4445 -ESSRGSTEKQVSDLENLLSKLKDELKNIKEDKSQLESKLKQAEAEKKATEDKLAKTEVE 4503
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGE-GCEAEKQGPEKTVLDLEPTIPSLNDAL 874
+ A E+ +KE DK A EN + E +K K DL+ + L L
Sbjct: 4504 KAAL----------EQAKKETEDKLANVENEKKATETQKNDLAKEKTDLQKALAKL---L 4550
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTD---NQEGHEAEIERKLEAS--NLTHNDELH 1039
+R +++ AEK+ALE++ + LE++ + + N E + E + KL+ + NL ++
Sbjct: 4551 KRQ-EQLDAEKKALEEKANALESEKKATEEKLANAEKEKKETQDKLKQTEDNLAKSESEK 4609
Query: 1040 KEKDDK-ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 1216
K +DK + ++ ++A ++ E K+ + E +L+Q + +A + E
Sbjct: 4610 KATEDKLKQTESEKAQIEAAKKETEDKLQNAENEKKAAEEKLKQSEEQKKATEEKLQEAE 4669
Query: 1217 AVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL 1396
A K+ ++++ ++EA + + K E LK+ + +L EA ++ K
Sbjct: 4670 AEKKAEQEKLANIEAEKQQLGNASEKQVSDLSGEISKLKQLLKQLAEAKKKADEELAKSK 4729
Query: 1397 KDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
+D ++ ++LQEDLN K+ +DLEK E S
Sbjct: 4730 QDKEQSDNDKSKLQEDLNNLKKQLEDLEKAKKESDS 4765
Score = 96.3 bits (238), Expect = 5e-17
Identities = 119/547 (21%), Positives = 233/547 (42%), Gaps = 44/547 (8%)
Frame = +2
Query: 8 LENKVADF-------EATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA 166
LENKV + + ++ L D+L +++++ + + N+R L K ++E + D +A
Sbjct: 3067 LENKVGNLTDQLNQVKNQLSALQDQLKSKENENEKLRNEREKLANEKNSVELQSKDKDAE 3126
Query: 167 KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 346
L + E D N++ + + ++ K + + +N L
Sbjct: 3127 IIKLKSDAEHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNLTNENKNMEQEKAKN 3186
Query: 347 XXIVSNLEVNILILHEELQKEKDDKTA------LIKDLVAAEPGKRTVNEIVSHLESKSR 508
+ N+E + L EE K +D+ + +KD + K +E + L +S
Sbjct: 3187 QEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKLAKSEEDNKLLKQSS 3246
Query: 509 SLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG----CEAEKQG 676
S E+ E+L + +L + + E+L+++KD S + N E + +
Sbjct: 3247 SGTTDKQVEDLQEMLNKLRDDLKNLNS-ENEQLKQQKDQLSEKLNNSNNDKTKAETQNEQ 3305
Query: 677 LEKTVLERRASNLDTM-----DAIHEE---ELRKEKV---------DKSALTENGEGCEA 805
L K LE+ + + M +AI ++ E+ KE + +K +L + +
Sbjct: 3306 LSKQ-LEQLNNEKNQMFNKYKNAIQDKAKVEIAKETLAKDNEKLASEKESLQQKLDSAND 3364
Query: 806 EKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ---EG 976
EK E+ LE LNDA + EK L ++ +DL K L + + E
Sbjct: 3365 EKNKLEQDKHKLEIDNTKLNDAKSH----LENEKSQLAQQINDLNNKLQKLEEEKNKLEE 3420
Query: 977 HEAEIERKLEASNLTHNDELHKEKDDK----ESIMNDLDHVKAERQVLESKVSDMETTYS 1144
+A+ E+KLE S D+L ++ D E I L + E+ LE + ++++ +
Sbjct: 3421 EKAQNEKKLENSQ-QDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQKNEIQNKLN 3479
Query: 1145 TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK---TGKDDDYNEA 1315
+ +++ + E + +E K +K++ + E ++I+ K T ++ E
Sbjct: 3480 EIEQQMKDSEKEKEDIKQKLQQVEQEKSETQKKLEEAEQQKNEIQNKLEQTEQEKKNLEN 3539
Query: 1316 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 1495
EK +KR+ E EEA L ++ + + + +E E + LN+ + ++LE E
Sbjct: 3540 EKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNE 3599
Query: 1496 LTSKLEK 1516
KLE+
Sbjct: 3600 TQKKLEE 3606
Score = 92.0 bits (227), Expect = 9e-16
Identities = 115/519 (22%), Positives = 220/519 (42%), Gaps = 14/519 (2%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E K A + + D N+K + +++ L+ L+ K+ DLE
Sbjct: 4089 QIVEEKSAVERQLVESQKDSSENQKQQDE----EKSKLQQQLSDLQNKLNDLEKKLADKE 4144
Query: 182 DELERKKDDNNAIIKKA--LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXX 352
+E E++K + + K+ L K +L+ + + +D+ D M I
Sbjct: 4145 NEKEQEKTQKDDLQKQLDQLQKDFDNLEREKQKLQDKNDSMKETIDSKNMLLDSFGTIKD 4204
Query: 353 IVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR 532
+++ N L +E K +DD + +N +++L+++ ++ +E L+
Sbjct: 4205 HLNDANNNNKKLQDENNKLRDDAQKATSKNNELQSIIDDLNRKLANLDAEKKATEEK-LK 4263
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
ED++ + A K E++LR+ ++ K E E EK+ +E + A+
Sbjct: 4264 NTEDKLKQAEAE-----KKATEDKLRETENAKKETEEKLAKTEEEKKQVEDKLAATEAAK 4318
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 892
+T E++L++ + +K A + EAEK E+ + E + + +
Sbjct: 4319 KET-----EDKLKQTEDEKKATEDKLANVEAEKSDIEQAKKETEDKLKQTEE----EKAA 4369
Query: 893 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMN 1072
V AEK+A E + + E D + E E + +E + D+L + +++K++ N
Sbjct: 4370 VEAEKKATEDKLHETEEAKKETEDKLKQTEDE-KAAVEQAKKETEDKLKQTEEEKKATEN 4428
Query: 1073 DLDHVKAERQVL-----------ESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 1219
L+ +AE++ L E +VSD+E S L +EL+ +D
Sbjct: 4429 KLEESEAEKKELGERFESSRGSTEKQVSDLENLLSKLKDELKNIKED------------- 4475
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 1399
K LE ++ EA E K K E EK L++ E E+ ++ + ++ K
Sbjct: 4476 -KSQLESKLKQAEAEKKATEDKLAK----TEVEKAALEQAKKETEDKLANVENEKK---- 4526
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
TE Q+ N +KEK DL+K + +L + E+
Sbjct: 4527 --------ATETQK--NDLAKEKTDLQKALAKLLKRQEQ 4555
Score = 87.0 bits (214), Expect = 3e-14
Identities = 103/519 (19%), Positives = 213/519 (41%), Gaps = 15/519 (2%)
Frame = +2
Query: 5 ALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND 184
ALE + + + + + ++ + + +K+ I +E K + K+ + E K + +
Sbjct: 3466 ALEQQKNEIQNKLNEIEQQMKDSEKEKEDIKQKLQQVEQEKSETQKKLEEAEQQKNEIQN 3525
Query: 185 ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSN 364
+LE+ + + K + + KA+ +R QE + N
Sbjct: 3526 KLEQTEQEK---------KNLENEKAETEKRLQETE-------------------EAKKN 3557
Query: 365 LEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED 544
L +L++ +++K + L AE + + + + K ++ + E
Sbjct: 3558 LANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQ--KAETQ 3615
Query: 545 EVLERSAS---NLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRAS 709
++LE++ NLA K+ E +L++ ++ K L E + + + EK ER+ +
Sbjct: 3616 KLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLN 3675
Query: 710 NLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLD 889
+ + + L EK + E E +AE Q + + + + + +R L
Sbjct: 3676 EAEEAN----KNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQ 3731
Query: 890 RVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIM 1069
K+ L S+ E K + + +AE ERKL + N L EK++ + +
Sbjct: 3732 ETEEAKKNLANEKSEAERK----LEEVQNEKAETERKLNEAEEA-NKNLENEKNETQKKL 3786
Query: 1070 NDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRV- 1246
+ + KAE Q L + + + +E ++K+ + E + LE K ++K++
Sbjct: 3787 EEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETE---EAKKNLEQEKSDIQKKLD 3843
Query: 1247 ------LDLE---ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 1399
++LE A + +T + E EK +KR+ E EEA L ++ + +
Sbjct: 3844 ETKQQKVNLENEKAETQKLLEETEEAKKNLENEKAETEKRLQETEEAKKNLANEKSEAER 3903
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ +E E + LN+ + ++LE E KLE+
Sbjct: 3904 KLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEE 3942
Score = 84.7 bits (208), Expect = 1e-13
Identities = 118/537 (21%), Positives = 228/537 (42%), Gaps = 36/537 (6%)
Frame = +2
Query: 2 QALENKVADFEATIATLN----DELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEA-- 163
Q L+NK+AD E+ I LN +++D K+ I N ++ K+ +E K ++E
Sbjct: 377 QNLKNKIADRESQIKALNLLIAQYQTDDEDKKEIIENLEKEIKDLKKQIEDKDKEIEVLK 436
Query: 164 AKTTLNDELERKKDDNNAIIKKALDKRISDL-KADAPQRDQEDDMNALIXXXXXXXXXXX 340
AK +E+ ++D + ++ D + D + +A Q ED + L
Sbjct: 437 AKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDDKKKNGV 496
Query: 341 XXXXIVSNLEVNILILHEELQ--KEKDDKTAL-IKDLVAAEPGKRTVN-EIVSHLESKSR 508
+++ + I L+E++Q K+++DK I++L + N E ++
Sbjct: 497 QMKQALASKDAEIEKLNEQIQELKDRNDKQEQNIEELNTKNSDLQNSNDEYKKLIDELQN 556
Query: 509 SLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT 688
LK+ L + + E + + S + + E+ E L E + ++E +GL+K+
Sbjct: 557 QLKD--LAKNKAESSDLNNSENTKQDSEKAEDENAETKSNKELQEESDKLKSENEGLKKS 614
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 868
+ + SN D + ++E + ++++ E E E+ +K D E I S
Sbjct: 615 LENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDK---DREIEILSSKV 671
Query: 869 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLT--------- 1021
+ +++ E D+ TDN+ + E E + T
Sbjct: 672 SSIENVNLDDDEDDITVVGTRDISVDETIPTDNETETKTEPETNTNTNENTNETNEENVS 731
Query: 1022 ----HNDELHKEKDDKESI-MNDLDHVKAERQ----VLESKVSDMETTYSTLNNELQQKM 1174
+N+E ++ K+DK+ + + L + A +Q L+S+ D+++ TL+ +
Sbjct: 732 SQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSKSNHELE 791
Query: 1175 DDNEAFLNERDGLEAVKQGL---EKRVLDLE--ATIHDIEMKTGKDDDYNEAEKQTLKKR 1339
N+ E + + K+G EK D+E + D++ + ++D E K LK +
Sbjct: 792 TKNKELEEEIENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYENEND-PETLKSLLKSK 850
Query: 1340 ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDL--EKRVLELTS 1504
+SELE TD L+K I +E L+ +L E + L E L+LT+
Sbjct: 851 LSELENLQKENTD----LMKQIEELKNENENLKRELENLKLENESLKRENERLQLTA 903
Score = 80.5 bits (197), Expect = 3e-12
Identities = 111/499 (22%), Positives = 228/499 (45%), Gaps = 8/499 (1%)
Frame = +2
Query: 38 TIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 217
T++ N EL + + + + + N + + E + +D+E +T + + E + +++
Sbjct: 2314 TLSKSNHELGTKTKELEEEIENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPE 2373
Query: 218 IIKKALDKRISDL----KADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILI 385
+K L ++S+L K + + D+ +N + N E+N L
Sbjct: 2374 TLKSLLKSKLSELENLQKENKAKEDEITKLNEELAKSEDAKRRELAETAERLNNEINTL- 2432
Query: 386 LHEELQKEKDDKTALIKDLVA--AEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLER 559
H+ELQ E++ + LI+DL + EP K + ++ LE KS + + +E+L R
Sbjct: 2433 -HDELQNEQNARQKLIEDLQSNNKEPEKDDNGDFMNVLEKKSDEINKAL-----EEILHR 2486
Query: 560 SASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHE 739
+ KA+R+ E K K L +KQ + + + S+ D + +
Sbjct: 2487 QNEEI---KALRDREAEKNKQTVDDL---------QKQ-IAMLNNKLKPSDQTDNDQLQK 2533
Query: 740 EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALE 919
E + +E +S N +A + + + L+ +I + N+ L++ L + A+E
Sbjct: 2534 ELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESINNQNEELKK-LRQKCDGVDAIE 2592
Query: 920 KRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAER 1099
+ + +A+ + DN E +AE E+++E +N K KD ++ N LD ++
Sbjct: 2593 LQLAQKKAELNEIKDNYEKEKAEREKEVEENN-------KKLKDTINALENRLD---SQG 2642
Query: 1100 QVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE 1279
+ SK++ E T ++ +D ++ + + L+A L+++ LE +
Sbjct: 2643 EQTRSKINSAEQT-------ARKAKEDADSAVIAQKSLQAELNNLKQKYAVLED-----Q 2690
Query: 1280 MKTGKDDDYNEAEK-QTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE-LQEDLNK 1453
+KT K++ EA++ + L + + I ++ +K KKL D N LSE + LQ+++N+
Sbjct: 2691 LKTEKENHQQEAQQLKELAEEDATPMVCIHVVGEKLKKLQND-NEKLSENNDNLQKNINE 2749
Query: 1454 ESKEKQDLEKRVLELTSKL 1510
+ LEK+ + ++L
Sbjct: 2750 LKDKINGLEKQYKQDAAEL 2768
Score = 80.5 bits (197), Expect = 3e-12
Identities = 111/530 (20%), Positives = 216/530 (40%), Gaps = 28/530 (5%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRN--------------ILEAAKQALEYKV 148
E K+ + I + D++ N+K+ K + N +LE K+ E
Sbjct: 2863 ETKLQNANQQIEMMKDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGLY 2922
Query: 149 ADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 328
D++++ LNDE +K D + K+ + +S LK + + + E
Sbjct: 2923 NDMKSSNDKLNDENRKKTDQIIDLTKQ--NAEVSALKLENQRLNSE-------------- 2966
Query: 329 XXXXXXXXIVSNLEV--NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESK 502
+ SN V N L +++++ K L + E K + + LES+
Sbjct: 2967 -----LEKLKSNQPVSSNDPELQKQIEELKKQLNNLSNEKKQIETEKNGLQGQIGRLESQ 3021
Query: 503 SRSLKE--HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 676
+ SL E ++E+ D++ + +E+R+E ++L +N E G
Sbjct: 3022 NESLIESKKDMKEQNDKL------------QAQMDEMRRE---NNSLRQNQTQLERTNNG 3066
Query: 677 LEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 856
LE V NL ++L + K SAL + + E E
Sbjct: 3067 LENKV-----GNL-------TDQLNQVKNQLSALQDQLKSKENE---------------- 3098
Query: 857 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNL 1018
N+ L+ + +++ EK ++E + D +A+ L + E +I + KL+ +N
Sbjct: 3099 --NEKLRNEREKLANEKNSVELQSKDKDAEIIKLKSDAEHLNDKINSLNDEKNKLQQAND 3156
Query: 1019 THNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN 1198
ND++ + K ++ N+ +++ E+ + K+ ++E L E + D+N N
Sbjct: 3157 KLNDQIEQMKQQINNLTNENKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNEN 3216
Query: 1199 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ----TLKKRISELEEAIS 1366
E + L+ TI ++ K K ++ N+ KQ T K++ +L+E ++
Sbjct: 3217 E--------------IQRLKDTIKELSDKLAKSEEDNKLLKQSSSGTTDKQVEDLQEMLN 3262
Query: 1367 ILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
L D K L + + +L E LN + +K E + +L+ +LE+
Sbjct: 3263 KLRDDLKNLNSENEQLKQQKDQLSEKLNNSNNDKTKAETQNEQLSKQLEQ 3312
Score = 73.9 bits (180), Expect = 3e-10
Identities = 102/519 (19%), Positives = 218/519 (42%), Gaps = 31/519 (5%)
Frame = +2
Query: 47 TLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL---EAAKTTLNDELERKKDDNNA 217
T N +L N D+ K ++++ L+ ++ DL +A + LN+ K+D A
Sbjct: 535 TKNSDLQNSNDEYKKLIDE----------LQNQLKDLAKNKAESSDLNNSENTKQDSEKA 584
Query: 218 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEE 397
+ A K +L+ ++ + E++ + +LE N+ +++
Sbjct: 585 EDENAETKSNKELQEESDKLKSENE-------------------GLKKSLE-NLKKSNDD 624
Query: 398 LQKEKDDKTALIKDLVAA-EPGKRTVNEI----------VSHLESKSRSLKEHFLREEED 544
L K +DK IK+L + K +NE+ + L SK S++ L ++ED
Sbjct: 625 LNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDED 684
Query: 545 EVLERSASNLAIMKAI---REEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
++ ++++ + I E E + E + + EN E N+
Sbjct: 685 DITVVGTRDISVDETIPTDNETETKTEPETNTNTNENTN--------------ETNEENV 730
Query: 716 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 895
+ + +EE+ + ++ K + + A KQG + + S N+ L + +
Sbjct: 731 SSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSKSNHEL 790
Query: 896 MAEKQALEKRCSDLEA-KNASLTDNQEGHEAEIERKLEASNLTHNDELHKE--KDDKESI 1066
+ + LE+ ++ K + D +E + E+ + + +E E K +S
Sbjct: 791 ETKNKELEEEIENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPETLKSLLKSK 850
Query: 1067 MNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG----- 1231
+++L++++ E L ++ +++ L EL+ +NE+ E + L+
Sbjct: 851 LSELENLQKENTDLMKQIEELKNENENLKRELENLKLENESLKRENERLQLTADQSPQSK 910
Query: 1232 ------LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 1393
L ++ LE+ + +++ KT NE E+ LKK +++E +K KK
Sbjct: 911 DKMIELLANQINQLESLVPELQQKT------NEIEE--LKKENKQIKEE----NEKLKKE 958
Query: 1394 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 1510
+D+ S + E++N +E++DL+K++ +L L
Sbjct: 959 NEDLK--KSGSNKSSEEIN---QEEEDLKKQIEDLKKAL 992
Score = 73.9 bits (180), Expect = 3e-10
Identities = 131/561 (23%), Positives = 228/561 (40%), Gaps = 54/561 (9%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQ--------------ALEY-- 142
E +V+D E ++ L DEL N K+DK + + EA K+ ALE
Sbjct: 4452 EKQVSDLENLLSKLKDELKNIKEDKSQLESKLKQAEAEKKATEDKLAKTEVEKAALEQAK 4511
Query: 143 -----KVADLE----AAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDM 295
K+A++E A +T ND + K D A+ K L KR L DA ++ E+
Sbjct: 4512 KETEDKLANVENEKKATETQKNDLAKEKTDLQKALAK--LLKRQEQL--DAEKKALEEKA 4567
Query: 296 NALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKD-LVAAEPGKRTV 472
NAL L E+ +KE DK +D L +E K+
Sbjct: 4568 NAL---------------ESEKKATEEKLANAEKEKKETQDKLKQTEDNLAKSESEKKAT 4612
Query: 473 NEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+ + ES+ + E +E ED++ N K EE+L++ ++ K A E +
Sbjct: 4613 EDKLKQTESEKAQI-EAAKKETEDKL-----QNAENEKKAAEEKLKQSEEQKKATEEKLQ 4666
Query: 653 GCEAEKQGLEKTV--LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK 826
EAEK+ ++ + +E L +L E L + + EA+K+ E+
Sbjct: 4667 EAEAEKKAEQEKLANIEAEKQQLGNASEKQVSDLSGEISKLKQLLK--QLAEAKKKADEE 4724
Query: 827 TVLDLEPTIPSLND--ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK 1000
+ S ND LQ DL+ + + + LEK + ++ N L D+ K
Sbjct: 4725 LAKSKQDKEQSDNDKSKLQEDLNNLKKQLEDLEKAKKESDSNNKLLADS--------VNK 4776
Query: 1001 LEASNLTHNDELHKEKD---DKESIMNDLDHVKAERQVLE-SKVSD------------ME 1132
L+ N +DE+ D + I N+ D VK ++ L+ SK ++ +
Sbjct: 4777 LKEQNKQKDDEIKNLTDKANQPQDINNNPDFVKVKKAFLQLSKTNEKLENEKKALEGAVN 4836
Query: 1133 TTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD------LEATIHDIEMKTGK 1294
+ YST+ + +D+ + + + + + Q + +D L ++D+ K
Sbjct: 4837 SIYSTMKKDDSAPLDEKATPMQQAERAKELIQNNSGKKVDPEFFEKLTNEMNDLFNSICK 4896
Query: 1295 DDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 1474
N +KK EE I+ + + L K + S +T+L D+ K+ ++ D
Sbjct: 4897 VFRTNSPITFDIKK-----EEDIATIGQNSIVLRK---VMKSYLTQLSNDIIKDKQQISD 4948
Query: 1475 L--EKRVLELTSKLEKCICGA 1531
L +K L++ ++ K A
Sbjct: 4949 LKHDKNSLQMENEEIKATASA 4969
Score = 70.9 bits (172), Expect = 2e-09
Identities = 91/524 (17%), Positives = 209/524 (39%), Gaps = 40/524 (7%)
Frame = +2
Query: 59 ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 238
+L ++ KK + N+++ E + ++ + A+ E + + +++ N KK +
Sbjct: 3638 KLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEE 3697
Query: 239 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDD 418
+ E+ L NL +L++ +++
Sbjct: 3698 AEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQNE 3757
Query: 419 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSAS---NLAIMKA 589
K + L AE + + + + K ++ + E ++LE++ NL K+
Sbjct: 3758 KAETERKLNEAEEANKNLENEKNETQKKLEEAEQQ--KAETQKLLEQTEEAKKNLENEKS 3815
Query: 590 IREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK 769
E++L++ ++ K L E EK ++K + E + ++ + E + E+ ++
Sbjct: 3816 ETEKKLQETEEAKKNL-------EQEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEE 3868
Query: 770 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 949
+ E E EK+ E + + + + +R L+ V EK E++ ++ E N
Sbjct: 3869 AKKNLENEKAETEKRLQETE--EAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEAN 3926
Query: 950 ASLTD-------------------------------NQEGHEAEIERKLEAS-----NLT 1021
+L + N E ++E E+KL+ + NL
Sbjct: 3927 KNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETEEAKKNLE 3986
Query: 1022 HN-DELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN 1198
++ K+ D+ + +L++ KAE Q L + + + E Q+K+D+
Sbjct: 3987 QEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKKNLENEKAETQKKLDE------ 4040
Query: 1199 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 1378
E K+ LE+ D E + +++ + E EK +K++ E E+A + +
Sbjct: 4041 ----AEEAKKNLEQEKSDAEKKLEEVQ----NEKSALENEKNETQKKLEEAEKAKDQIVE 4092
Query: 1379 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 1510
+ + + + + + E+ ++ +EK L++++ +L +KL
Sbjct: 4093 EKSAVERQL---VESQKDSSENQKQQDEEKSKLQQQLSDLQNKL 4133
Score = 70.1 bits (170), Expect = 4e-09
Identities = 138/581 (23%), Positives = 243/581 (41%), Gaps = 94/581 (16%)
Frame = +2
Query: 56 DELLNEKDD-KKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 232
+EL NE ++ KK I + +L + E+K E K N+EL+++ D+ +K+A
Sbjct: 1536 EELKNENNELKKQIEALKRVLGYPEDGNEHKTPS-ELIKE--NEELKKQNDN----LKRA 1588
Query: 233 LD--------KRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVSNLEVNILI 385
L K S+L A+ + +E DD+ + I N
Sbjct: 1589 LGYPEDGKDHKSPSELIAEIEELKKENDDLKRALGYPEDDKDHKSPSELIKEN------- 1641
Query: 386 LHEELQKEKDD--KTALIKDLVAAEPGKRTVNEIVSHLESKSRSL------KEHFLREE- 538
EEL+KE DD K I +AE + E+ +E ++L KEH E
Sbjct: 1642 --EELKKENDDLKKRLGISGESSAEESN-SPEELKKQIEDLKKALGYPEDGKEHKTPSEL 1698
Query: 539 --EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV------- 691
E+E L++ N A+ +A+ E K+ S L++ E + + + LEK +
Sbjct: 1699 IKENEELKKQ--NDALKRALGYPEDGKDHKSPSELIQENEELKKKVEDLEKALGYPQDGK 1756
Query: 692 --------------LERRASNLD---TMDAIHEEELR------KEKVD--KSALTENGEG 796
L+++ D T D EEL+ K++++ K AL +G
Sbjct: 1757 DHKSPSELLKENEELKKKLGISDESSTEDNKSPEELKNENKYLKKQIEGLKKALGYPEDG 1816
Query: 797 CE--------AEKQGPEKTVLDLEPTIPSLNDALQ-RDLDRVMAEKQALEKRCSDLEAKN 949
E E + +K V DLE + D + + ++ E + L+K L+ +N
Sbjct: 1817 KEHKSPSELIQENEDLKKKVSDLEKALGYPEDGKEHKSPSELLKENEELKKENQRLKKEN 1876
Query: 950 ASL---------------------TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESI 1066
A L +D E +++ E K E NL E K +E++
Sbjct: 1877 AELKKRLGIPVDQIIEGIMNESTASDESEDNKSPEELKREIENLKKQLEDLKNSGSQENV 1936
Query: 1067 MNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDN----EAFLNERDGLEAVKQGL 1234
+ + +K L + + ++LQQK+DD E + + +E + +
Sbjct: 1937 DEENNEMKEGADNLIDALQQSVDEKNKQIDDLQQKLDDQNREIELLKAKVEQIENINEEE 1996
Query: 1235 EKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIW 1414
+ + + +T D+E++ +++ EA K+ L ++IS+L++ LT+K K L+
Sbjct: 1997 DNEDIVVAST-RDVELENVEEESPEEA-KERLAEQISQLQDK---LTEKKKNSLQMKQAL 2051
Query: 1415 LS---EVTELQEDLNKESKEKQD----LEKRVLELTSKLEK 1516
S E+++L E++ + EK+D LEK ELT LEK
Sbjct: 2052 ASKDAEISKLNEEIEQIKSEKEDQDKELEKLNNELTEALEK 2092
Score = 67.8 bits (164), Expect = 2e-08
Identities = 119/563 (21%), Positives = 238/563 (42%), Gaps = 74/563 (13%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
I TL+DEL NE++ ++ ++ D L++ + E + + LE+K D+ N
Sbjct: 2429 INTLHDELQNEQNARQKLIED---LQSNNKEPE------KDDNGDFMNVLEKKSDEINKA 2479
Query: 221 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEEL 400
+++ L ++ ++KA RD+E + N V +L+ I +L+ +L
Sbjct: 2480 LEEILHRQNEEIKA---LRDREAEKNK----------------QTVDDLQKQIAMLNNKL 2520
Query: 401 Q-KEKDDKTALIKDLVAAE-----PGKRT----------VNEIVSHLESKSRSLKEHF-- 526
+ ++ D L K+L+ E P R NEI++ L+ + E
Sbjct: 2521 KPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESINNQNEELKK 2580
Query: 527 LREEEDEV-------------LERSASNLAIMKAIREEEL----RKEKDGKSALVEN--- 646
LR++ D V L N KA RE+E+ +K KD +AL
Sbjct: 2581 LRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTINALENRLDS 2640
Query: 647 -GEGCEAEKQGLEKTV----------------LERRASNLDTMDAIHEEELRKEKVDKSA 775
GE ++ E+T L+ +NL A+ E++L+ EK +
Sbjct: 2641 QGEQTRSKINSAEQTARKAKEDADSAVIAQKSLQAELNNLKQKYAVLEDQLKTEKENHQQ 2700
Query: 776 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNAS 955
+ + E P + + + L Q D +++ L+K ++L+ K
Sbjct: 2701 EAQQLKELAEEDATPMVCIHVVGEKLKKL----QNDNEKLSENNDNLQKNINELKDKING 2756
Query: 956 LTDNQEGHEAEIER--------KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLE 1111
L + AE+ + +A+NL + ++ KE++ E +MN ++ E+Q L
Sbjct: 2757 LEKQYKQDAAELSNVHHQLGALQEKATNLENENKSLKEEN--EDLMNQNKQLEKEKQQLL 2814
Query: 1112 SKVSDMETTYSTLNNELQQKMDDNEAFLNERDG----LEAVKQGLEKRVLDLEATIHDIE 1279
++ S++E + L + N+ L + D LE +K+ + L+ IE
Sbjct: 2815 AQNSNLEENKNNQEQSLMNRKKKNDDLLKQIDDLKLELEELKRNNSQNETKLQNANQQIE 2874
Query: 1280 MKTGKDDDYNEAEK-QTLKKRISELE------EAISILTDKAKKLLKDINIWLSEVTELQ 1438
M KD N+ E+ ++ + ++++L+ + I+ + KK+ + + +++
Sbjct: 2875 MM--KDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGL---YNDMKSSN 2929
Query: 1439 EDLNKESKEKQDLEKRVLELTSK 1507
+ LN E+++K D ++++LT +
Sbjct: 2930 DKLNDENRKKTD---QIIDLTKQ 2949
Score = 65.9 bits (159), Expect = 7e-08
Identities = 118/636 (18%), Positives = 254/636 (39%), Gaps = 134/636 (21%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+A+E+K F IA L + + N+ ++ K + + ++A + L K A+L K
Sbjct: 2554 KAIEDK---FNEIIAKLQESINNQNEELKKLRQKCDGVDAIELQLAQKKAELNEIKDNYE 2610
Query: 182 DEL---ERKKDDNNAIIK---KALDKRISDL---------KADAPQRDQEDDMNALIXXX 316
E E++ ++NN +K AL+ R+ A+ R ++D ++ +
Sbjct: 2611 KEKAEREKEVEENNKKLKDTINALENRLDSQGEQTRSKINSAEQTARKAKEDADSAVIAQ 2670
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKD---------------DKTALIKDLVAA 451
++NL+ +L ++L+ EK+ D T ++ V
Sbjct: 2671 KSLQAE-------LNNLKQKYAVLEDQLKTEKENHQQEAQQLKELAEEDATPMVCIHVVG 2723
Query: 452 EPGKRTVNEI-------------VSHLESKSRSLKEHFLREEED--------EVLERSAS 568
E K+ N+ ++ L+ K L++ + ++ + L+ A+
Sbjct: 2724 EKLKKLQNDNEKLSENNDNLQKNINELKDKINGLEKQYKQDAAELSNVHHQLGALQEKAT 2783
Query: 569 NLAIM-KAIREE---------ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 718
NL K+++EE +L KEK L+ E K E++++ R+ N D
Sbjct: 2784 NLENENKSLKEENEDLMNQNKQLEKEKQ---QLLAQNSNLEENKNNQEQSLMNRKKKNDD 2840
Query: 719 TMDAIHEEELRKEKVDKS------------------------------------------ 772
+ I + +L E++ ++
Sbjct: 2841 LLKQIDDLKLELEELKRNNSQNETKLQNANQQIEMMKDQINNDKEQIKSAQDKLNDLQNK 2900
Query: 773 --ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM------AEKQALEKRC 928
L N E +K+ E D++ + LND ++ D+++ AE AL+
Sbjct: 2901 NNELNSNQIVLENQKKMYEGLYNDMKSSNDKLNDENRKKTDQIIDLTKQNAEVSALKLEN 2960
Query: 929 SDLEAKNASLTDNQ--EGHEAEIERKLEASNLTHNDELHKEKD---DKESIMNDLDHVKA 1093
L ++ L NQ ++ E+++++E N+ +++K +K + + +++
Sbjct: 2961 QRLNSELEKLKSNQPVSSNDPELQKQIEELKKQLNNLSNEKKQIETEKNGLQGQIGRLES 3020
Query: 1094 ERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHD 1273
+ + L DM+ L ++ + +N + + LE GLE +V +L ++
Sbjct: 3021 QNESLIESKKDMKEQNDKLQAQMDEMRRENNSLRQNQTQLERTNNGLENKVGNLTDQLNQ 3080
Query: 1274 I---------EMKTGKDDD---YNEAEKQTLKKRISELE------EAISILTDKAKKLLK 1399
+ ++K+ ++++ NE EK +K EL+ E I + +D A+ L
Sbjct: 3081 VKNQLSALQDQLKSKENENEKLRNEREKLANEKNSVELQSKDKDAEIIKLKSD-AEHLND 3139
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 1507
IN E +LQ+ +K + + + +++++ LT++
Sbjct: 3140 KINSLNDEKNKLQQANDKLNDQIEQMKQQINNLTNE 3175
Score = 64.7 bits (156), Expect = 2e-07
Identities = 124/555 (22%), Positives = 219/555 (39%), Gaps = 69/555 (12%)
Frame = +2
Query: 53 NDELLNEKDDKKCI-VNDRNILEAAKQ----ALEYKVADLEAAKTTL---NDELERKKDD 208
N+E K+DKK + + L A+KQ AL+ + DL++ TL N ELE K +
Sbjct: 737 NEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSKSNHELETKNKE 796
Query: 209 ---------NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
NN + +K SD++ RD + + +
Sbjct: 797 LEEEIENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYE------------NENDPETLK 844
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
+L + L E LQKE D L+K + + + + +L+ ++ SLK E
Sbjct: 845 SLLKSKLSELENLQKENTD---LMKQIEELKNENENLKRELENLKLENESLKR------E 895
Query: 542 DEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT 721
+E L+ +A K E L + + +LV + E + L+K + + N
Sbjct: 896 NERLQLTADQSPQSKDKMIELLANQINQLESLVPELQQKTNEIEELKKENKQIKEEN--- 952
Query: 722 MDAIHEEELRKEKVD--KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL-DR 892
E+L+KE D KS ++ E E++ +K + DL+ + D +
Sbjct: 953 ------EKLKKENEDLKKSGSNKSSEEINQEEEDLKKQIEDLKKALGYPQDGKEHKTPSE 1006
Query: 893 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKE---- 1060
++ E + L+K+ DLE ++ +DN+ E K + L N+EL K+ DD E
Sbjct: 1007 LIEENEELKKKVEDLEKESGYPSDNK-------EHKSPSELLKENEELKKKVDDLEKALG 1059
Query: 1061 ------------SIMNDLDHVKAERQVL--------ESKVSDMETTYSTLNNELQQKMDD 1180
++ + + +K + L + K + N EL++K+ D
Sbjct: 1060 YPEDGKDHKSPSELIKENEELKKQNDALKRALGYPEDGKDHKSPSELIQENEELKKKVAD 1119
Query: 1181 NEAFL-------NERDGLEAVKQGLE-KRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKK 1336
E L + E +++ E K+ L + + + + K + +E + LKK
Sbjct: 1120 LEKALGYPADGQEHKTPSELLRENEELKKKLGISDSTTPSDNEDNKSPEELRSENKDLKK 1179
Query: 1337 RISELEEAISILTD-----------KAKKLLKDINIWLSEVTELQEDLNKES------KE 1465
+I +L+ A+ D K + LK N L + ED KE
Sbjct: 1180 QIEDLKRALGYPEDGKEHKTPSELIKENEELKKQNDSLKKALGYSEDGKDHKSPSELIKE 1239
Query: 1466 KQDLEKRVLELTSKL 1510
+DL+K+V +L L
Sbjct: 1240 NEDLKKKVEDLEKAL 1254
Score = 64.3 bits (155), Expect = 2e-07
Identities = 113/530 (21%), Positives = 213/530 (40%), Gaps = 27/530 (5%)
Frame = +2
Query: 2 QALENKVADFEATIATLND--------ELLNEKDD--KKCIVNDRNILEAAKQALE---- 139
+ L+ KV D E + D ELL E ++ KK ++D + E K E
Sbjct: 1736 EELKKKVEDLEKALGYPQDGKDHKSPSELLKENEELKKKLGISDESSTEDNKSPEELKNE 1795
Query: 140 --YKVADLEAAKTTLN---DELERKKDDNNAIIKKALDKRISDL-KADAPQRDQEDDMNA 301
Y +E K L D E K + L K++SDL KA D ++ +
Sbjct: 1796 NKYLKKQIEGLKKALGYPEDGKEHKSPSELIQENEDLKKKVSDLEKALGYPEDGKEHKSP 1855
Query: 302 LIXXXXXXXXXXXXXXXIVSNLEVNILI---LHEELQKEKDDKTAL--IKDLVAAEPGKR 466
N E+ + + + ++ ++ TA +D + E KR
Sbjct: 1856 SELLKENEELKKENQRLKKENAELKKRLGIPVDQIIEGIMNESTASDESEDNKSPEELKR 1915
Query: 467 TVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVEN 646
+ + LE S + + EE +E+ E A NL + L++ D K+ +++
Sbjct: 1916 EIENLKKQLEDLKNSGSQENVDEENNEMKE-GADNLI-------DALQQSVDEKNKQIDD 1967
Query: 647 GEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEK 826
+ +K + +E + ++ ++ I+EEE ++ V S T + E E++ PE+
Sbjct: 1968 LQ----QKLDDQNREIELLKAKVEQIENINEEEDNEDIVVAS--TRDVELENVEEESPEE 2021
Query: 827 TVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLE 1006
L I L D L + KQAL + +AEI +
Sbjct: 2022 AKERLAEQISQLQDKLTEKKKNSLQMKQALASK------------------DAEISKL-- 2061
Query: 1007 ASNLTHNDELHKEKDDKESIMNDLDHVKAE-RQVLESKVSDMETTYSTLNNELQQK-MDD 1180
N+E+ + K +KE +L+ + E + LE + + + NNE ++ +DD
Sbjct: 2062 ------NEEIEQIKSEKEDQDKELEKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDD 2115
Query: 1181 NEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEA 1360
E ER+ L++ + L+ + + E +E +DD N++ + + +I ELE
Sbjct: 2116 IEKLKEERENLKSENESLKNQAPENEGLKKSLENLKKSNDDLNKSNEDK-ENKIKELE-- 2172
Query: 1361 ISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 1510
SE+++L+ ++N+ + +D ++ + L+SK+
Sbjct: 2173 -------------------SEISKLKSEINELEQNNKDKDREIEILSSKV 2203
Score = 61.6 bits (148), Expect = 1e-06
Identities = 77/385 (20%), Positives = 178/385 (46%), Gaps = 12/385 (3%)
Frame = +2
Query: 392 EELQKEKDDKTALIKDLVAAEPGKRTVNEI--VSHLESKSRSLKEHFLREEEDEVLERSA 565
E L+ E + K A ++ L A K+ + + +E++ ++LK + + E ++ A
Sbjct: 337 ESLRLELEKKNAELEQLKARYQSKQDPQLLAEIERIENEVQNLKNK-IADRESQI---KA 392
Query: 566 SNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDA--IHE 739
NL I + ++E +KE ++EN E E + L+K + E + ++ + A
Sbjct: 393 LNLLIAQYQTDDEDKKE------IIEN---LEKEIKDLKKQI-EDKDKEIEVLKAKIAKI 442
Query: 740 EELRKEKVDKSALTENGEGCE-AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQAL 916
EE+ +++ D+ + + + E + LE + L + L + KQAL
Sbjct: 443 EEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDDKKKNGVQMKQAL 502
Query: 917 EKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAE 1096
+ +++E N + + ++ ++ + E+ +E N T N +L D+ + ++++L + +
Sbjct: 503 ASKDAEIEKLNEQIQELKDRNDKQ-EQNIEELN-TKNSDLQNSNDEYKKLIDELQNQLKD 560
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDD-------NEAFLNERDGLEAVKQGLEKRVLDL 1255
+++ SD+ + +T + +K +D N+ E D L++ +GL+K + +L
Sbjct: 561 LAKNKAESSDLNNSENTKQDS--EKAEDENAETKSNKELQEESDKLKSENEGLKKSLENL 618
Query: 1256 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 1435
+ + +DD N++ + + +I ELE SE+++L
Sbjct: 619 KKS----------NDDLNKSNEDK-ENKIKELE---------------------SEISKL 646
Query: 1436 QEDLNKESKEKQDLEKRVLELTSKL 1510
+ ++N+ + +D ++ + L+SK+
Sbjct: 647 KSEINELEQNNKDKDREIEILSSKV 671
Score = 60.1 bits (144), Expect = 4e-06
Identities = 110/548 (20%), Positives = 229/548 (41%), Gaps = 46/548 (8%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA------- 166
L+ KV+D E + D E ++ + L+ Q L+ + A+L+
Sbjct: 1832 LKKKVSDLEKALGYPEDG--KEHKSPSELLKENEELKKENQRLKKENAELKKRLGIPVDQ 1889
Query: 167 -------KTTLNDELERKKDDNNAIIKKALD---KRISDLKADAPQRDQEDDMNALIXXX 316
++T +DE E K +K+ ++ K++ DLK Q + +++ N +
Sbjct: 1890 IIEGIMNESTASDESEDNKSPEE--LKREIENLKKQLEDLKNSGSQENVDEENNEM---- 1943
Query: 317 XXXXXXXXXXXXIVSNLEVNILILH---EELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 487
++ L+ ++ + ++LQ++ DD+ I+ L A +NE
Sbjct: 1944 ------KEGADNLIDALQQSVDEKNKQIDDLQQKLDDQNREIELLKAKVEQIENINEEED 1997
Query: 488 HLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAE 667
+ + S ++ L E+E E + LA + +++L ++K + + +AE
Sbjct: 1998 NEDIVVASTRDVELENVEEESPEEAKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAE 2057
Query: 668 KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEP 847
L + + + ++ D + E+L E + ENG+ +++Q E
Sbjct: 2058 ISKLNEEIEQIKSEKEDQDKEL--EKLNNELTEALEKLENGKKKSSQEQNNEN------- 2108
Query: 848 TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNL-TH 1024
+ D++++ E++ +L+++N SL NQ +++ LE NL
Sbjct: 2109 -----EEDFVDDIEKLKEERE-------NLKSENESL-KNQAPENEGLKKSLE--NLKKS 2153
Query: 1025 NDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNE---LQQKMD--DNEA 1189
ND+L+K +DKE N + +++E L+S+++++E + E L K+ +N
Sbjct: 2154 NDDLNKSNEDKE---NKIKELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVN 2210
Query: 1190 FLNERDGLEAVKQGLEKRVLDLEATI---------HDIEMKTGKDDDYNEAEKQTLKKRI 1342
++ D + V R + ++ TI + E T +++ NE ++ + +
Sbjct: 2211 LDDDEDDITVV----GTRDISVDETIPTDNETETKTEPETNTNTNENTNETNEENVSSQE 2266
Query: 1343 SELEEAISILTDKAKKLLKDINIWLS----EVTELQ---EDLNKE----SKEKQDLEKRV 1489
EE DK K ++ + L+ EV L+ +DL E SK +L +
Sbjct: 2267 GNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSKSNHELGTKT 2326
Query: 1490 LELTSKLE 1513
EL ++E
Sbjct: 2327 KELEEEIE 2334
>ref|XP_804789.1| R27-2 protein [Trypanosoma cruzi strain CL Brener]
gi|70867933|gb|EAN82938.1| R27-2 protein, putative
[Trypanosoma cruzi]
Length = 1597
Score = 110 bits (274), Expect = 3e-21
Identities = 120/538 (22%), Positives = 229/538 (42%), Gaps = 32/538 (5%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L ++A EA I L ++L + D + + + EA + L ++A EA L
Sbjct: 649 EKLTEELAQREADIEKLAEDLAQREADNEKLTEELAQREADNEKLAEELAQREADIEKLA 708
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+EL +++ DN + ++ + + K +E D L ++
Sbjct: 709 EELAQREADNEKLAEELAQREADNEKLTEDLAQREADNEKLTEDLAQREADIEKLTEELA 768
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
E +I L EEL + + D L +DLV E + E ++ E+ + L E + E
Sbjct: 769 QREADIEKLTEELVQREADIEKLTEDLVQREADIEKLTEDLAQREADNEKLAEDLAQREA 828
Query: 542 DEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
D E+ +LA +A E E+L + + L E+ EA+ + L + + +R A N
Sbjct: 829 DN--EKLTEDLAQREADNEKLAEDLAQREADNEKLTEDLAQREADNEKLTEDLAQREADN 886
Query: 713 ------LDTMDAIHE---EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN 865
L +A +E EEL + + D LTE EA+ + + ++ E I L
Sbjct: 887 EKLTEDLAQREADNEKLTEELVQREADNEKLTEELAQREADNEKLTEDLVQREADIEKLT 946
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHN 1027
+ DL + A+ + L + + EA N LT++ EA+IE+ + EA
Sbjct: 947 E----DLAQREADNEKLTEDLAQREADNEKLTEDLVQREADIEKLTEDLVQREADIEKLT 1002
Query: 1028 DELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDD----NEAFL 1195
++L + + D E + DL +A+ + L ++ E L +L Q+ D E +
Sbjct: 1003 EDLVQREADIEKLTEDLAQREADNEKLTEDLAQREADIEKLTEDLVQREADIEKLTEDLV 1062
Query: 1196 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD------YNEAEKQTLKKRISELEE 1357
+E + + L +R D E ++ + ++ EA+ + L + +++ E
Sbjct: 1063 QREADIEKLTEDLAQREADNEKLAEELAQREADNEKLAEELVQREADNEKLAEELAQWEA 1122
Query: 1358 AISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE----KQDLEKRVLELTSKLEKC 1519
L ++ + DI ++ + + D K ++E + D+EK ++L+ K +C
Sbjct: 1123 DNEKLAEELAQREADIEKLTEDLAQREADNEKLAEELVQREADIEKLAVDLSQKEAEC 1180
Score = 75.5 bits (184), Expect = 9e-11
Identities = 92/381 (24%), Positives = 161/381 (42%), Gaps = 4/381 (1%)
Frame = +2
Query: 380 LILHEELQKEKDDKTALIKDLV-AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLE 556
L+ H E++ + ++ +L +A P N V RS E F DE+ +
Sbjct: 446 LVAHREMRNARINERLSHPELCDSASPQVPPPNTDVPVAPEVVRS--EPFYCVTLDELNK 503
Query: 557 RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 736
N + +A+ + E EK L E EA+ + L + +++R A N
Sbjct: 504 TGTLNEQLTRALAQREADNEK-----LTEELAQREADNEKLAEELVQREADNEKLT---- 554
Query: 737 EEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-QRDLDRVMAEKQA 913
EEL + D LTE+ EA+ + + + E I L + L QR+ D + +
Sbjct: 555 -EELAHREADIEKLTEDLAQREADIEKLAEDLAQREADIEKLTEELAQREAD-IEKLTEE 612
Query: 914 LEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDKESIMNDLDHV 1087
L +R +D+E L + +E E + EA N +EL + + D E + DL
Sbjct: 613 LAQREADIEKLTEELAQREADNEKLTEELAQREADNEKLTEELAQREADIEKLAEDLAQR 672
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 1267
+A+ + L +++ E L EL Q+ D E E EA + L + + EA
Sbjct: 673 EADNEKLTEELAQREADNEKLAEELAQREADIEKLAEELAQREADNEKLAEELAQREAD- 731
Query: 1268 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 1447
K +D EA+ + L + +++ E I LT++ + DI E+ + + D+
Sbjct: 732 ---NEKLTEDLAQREADNEKLTEDLAQREADIEKLTEELAQREADIEKLTEELVQREADI 788
Query: 1448 NKESKEKQDLEKRVLELTSKL 1510
K +++ E + +LT L
Sbjct: 789 EKLTEDLVQREADIEKLTEDL 809
Score = 60.1 bits (144), Expect = 4e-06
Identities = 96/502 (19%), Positives = 191/502 (38%), Gaps = 26/502 (5%)
Frame = +2
Query: 89 CIVNDR-NILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKAD 265
C+ D N + L +A EA L +EL +++ DN + ++ + + + K
Sbjct: 122 CVTLDELNKTGTLNEQLTRALAQREADNEKLTEELAQREADNEKLAEELVQREADNEKLT 181
Query: 266 APQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLV 445
+E D L ++ E + L E+L + + D L +DL
Sbjct: 182 EELAQREADNEKLTEELAQREADNEKLAEELAQREADNEKLTEDLAQREADNEKLAEDLA 241
Query: 446 AAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG 625
E + E ++ E+ + L E + E D +E+ A +LA +A E+L ++
Sbjct: 242 QREADNEKLTEELAQREADNEKLTEELAQREAD--IEKLAEDLAQREA-DNEKLAEDLAQ 298
Query: 626 KSALVENGE--------GCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALT 781
+ A++E E G + + LE+ R + +D + E EL V AL
Sbjct: 299 REAVIEGAEADASKTIEGVYSRCRELEELAARRELAATGDVDIL-ERELADALVQLKALE 357
Query: 782 ENGEGCEAEKQGPEKTVLDLEP----TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKN 949
A + +++ ++ L L + E+ EK S
Sbjct: 358 GENAALAALLAAKKAEMVEASDAAGKSVRELESRLSAAVSEASHERAMAEKLISTTRGAL 417
Query: 950 ASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMND-LDHVK----AERQV--- 1105
++ + + ++ + + T EL ++ + + +N+ L H + A QV
Sbjct: 418 TAMVEENQKQVEQLRADHDQARATMQAELVAHREMRNARINERLSHPELCDSASPQVPPP 477
Query: 1106 -----LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIH 1270
+ +V E Y +EL + NE EA + L + + EA
Sbjct: 478 NTDVPVAPEVVRSEPFYCVTLDELNKTGTLNEQLTRALAQREADNEKLTEELAQREAD-- 535
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN 1450
K ++ EA+ + L + ++ E I +KL +D+ +++ +L EDL
Sbjct: 536 --NEKLAEELVQREADNEKLTEELAHREADI-------EKLTEDLAQREADIEKLAEDLA 586
Query: 1451 KESKEKQDLEKRVLELTSKLEK 1516
+ + + L + + + + +EK
Sbjct: 587 QREADIEKLTEELAQREADIEK 608
>ref|XP_808187.1| myosin heavy chain [Trypanosoma cruzi strain CL Brener]
gi|70872338|gb|EAN86336.1| myosin heavy chain, putative
[Trypanosoma cruzi]
Length = 3543
Score = 109 bits (273), Expect = 4e-21
Identities = 123/521 (23%), Positives = 215/521 (41%), Gaps = 16/521 (3%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L ++A EA I L DEL + D + + D EA + L +A EA L
Sbjct: 2679 EKLVEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADIEKLT 2738
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
DEL +++ DN ++++ + K +E D L ++
Sbjct: 2739 DELAQREADNEKLVEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLTEDLA 2798
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
E + L E+L + + D L +DL E + E ++ E+ + L E + E
Sbjct: 2799 QREADNEKLAEDLAQREADIEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREA 2858
Query: 542 DEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
D +E+ A +LA +A E EEL + + L E+ EA+ + L + + +R A N
Sbjct: 2859 D--IEKLAEDLAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLAEDLAQREADN 2916
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-QRDLD 889
EEL + + D L E+ EA+ + + + E I L D L QR+
Sbjct: 2917 EKL-----AEELAQREADIEKLAEDLAQREADNEKLAEDLAQREADIEKLTDELAQRE-- 2969
Query: 890 RVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHNDELHKEKD 1051
A+ + L + + EA N L + EA+IE+ + EA DEL + +
Sbjct: 2970 ---ADNEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADIEKLTDELAQREA 3026
Query: 1052 DKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQG 1231
D E + DL +A+ + L ++ E L EL Q+ D E +E EA +
Sbjct: 3027 DNEKLAEDLAQREADNEKLTDDLAQREADNEKLVEELAQREADIEKLTDELAQREADNEK 3086
Query: 1232 LEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS---ILTDKAKKLLKD 1402
L + + EA + + + + NE + L +R ++ + ++ ++ K +
Sbjct: 3087 LAEDLAQREADNEKLVEELAQREADNEKLAEDLVRREADCHKLVAELDVIESKLNSAMSG 3146
Query: 1403 INIWLS---EVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++++ S V E+ E + + EK LE S K
Sbjct: 3147 LHVFSSGDGGVIEMLEGYMERASLVSGAEKDALERLSLSNK 3187
Score = 108 bits (271), Expect = 7e-21
Identities = 120/517 (23%), Positives = 219/517 (42%), Gaps = 10/517 (1%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L +++A EA L ++L + D + + D EA + L ++A EA L
Sbjct: 2637 EKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLVEELAQREADIEKLT 2696
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
DEL +++ DN + + + + K +E D+ L ++
Sbjct: 2697 DELAQREADNEKLAEDLAQREADNEKLAEDLAQREADIEKLTDELAQREADNEKLVEELA 2756
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
E +I L +EL + + D L +DL E + E ++ E+ + L E + E
Sbjct: 2757 QREADIEKLTDELAQREADNEKLAEDLAQREADNEKLTEDLAQREADNEKLAEDLAQREA 2816
Query: 542 DEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
D +E+ A +LA +A E E+L + + L E EA+ + L + + +R A N
Sbjct: 2817 D--IEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADN 2874
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 892
EEL + + D L E+ EA+ EK DL + N+ L +L +
Sbjct: 2875 EKL-----AEELAQREADNEKLAEDLAQREADN---EKLAEDLAQR-EADNEKLAEELAQ 2925
Query: 893 VMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMN 1072
A+ + L + + EA N L ++ EA+IE+ DEL + + D E +
Sbjct: 2926 READIEKLAEDLAQREADNEKLAEDLAQREADIEKL--------TDELAQREADNEKLAE 2977
Query: 1073 DLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 1252
DL +A+ + L +++ E L +L Q+ D E +E EA + L + +
Sbjct: 2978 DLAQREADNEKLAEELAQREADIEKLAEDLAQREADIEKLTDELAQREADNEKLAEDLAQ 3037
Query: 1253 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKA-------KKLLKDINI 1411
EA K D EA+ + L + +++ E I LTD+ +KL +D+
Sbjct: 3038 READ----NEKLTDDLAQREADNEKLVEELAQREADIEKLTDELAQREADNEKLAEDLAQ 3093
Query: 1412 WLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCI 1522
++ +L E+L + + + L + ++ + K +
Sbjct: 3094 READNEKLVEELAQREADNEKLAEDLVRREADCHKLV 3130
Score = 105 bits (262), Expect = 8e-20
Identities = 116/522 (22%), Positives = 223/522 (42%), Gaps = 17/522 (3%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L ++A EA I L ++L + D + + + EA + L +A EA L
Sbjct: 2581 EKLAEELAQREADIEKLAEDLAQREADNEKLAEELAQREADIEKLAEDLAQREADIEKLT 2640
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
DEL +++ DN + + + + K +E D L+ ++
Sbjct: 2641 DELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLVEE--------------LA 2686
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
E +I L +EL + + D L +DL E + E ++ E+ L + + E
Sbjct: 2687 QREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADIEKLTDELAQREA 2746
Query: 542 D--EVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
D +++E A A ++ + +E ++E D + L E+ EA+ + L + + +R A N
Sbjct: 2747 DNEKLVEELAQREADIEKLTDELAQREADNEK-LAEDLAQREADNEKLTEDLAQREADNE 2805
Query: 716 DTMDAIHE---------EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 868
+ + + E+L + + D L E+ EA+ + + + E I +
Sbjct: 2806 KLAEDLAQREADIEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADI----E 2861
Query: 869 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHND 1030
L DL + A+ + L + + EA N L ++ EA+ E+ + EA N +
Sbjct: 2862 KLAEDLAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAE 2921
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 1210
EL + + D E + DL +A+ + L ++ E L +EL Q+ DNE +
Sbjct: 2922 ELAQREADIEKLAEDLAQREADNEKLAEDLAQREADIEKLTDELAQREADNEKLAEDLAQ 2981
Query: 1211 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 1390
EA + L + + EA DIE K +D EA+ + L +++ E +K
Sbjct: 2982 READNEKLAEELAQREA---DIE-KLAEDLAQREADIEKLTDELAQREA-------DNEK 3030
Query: 1391 LLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
L +D+ ++ +L +DL + + + L + + + + +EK
Sbjct: 3031 LAEDLAQREADNEKLTDDLAQREADNEKLVEELAQREADIEK 3072
Score = 101 bits (252), Expect = 1e-18
Identities = 123/558 (22%), Positives = 231/558 (41%), Gaps = 21/558 (3%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L +++A EA I L DEL + D + + ++ EA + L +A EA L
Sbjct: 1205 EKLTDELAQREADIEKLTDELAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLA 1264
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
++L +++ DN + + + + K +E D L ++
Sbjct: 1265 EDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADNEKLTEELA 1324
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
E + L E+L + + D L +DL E + E ++ E+ + L E + E
Sbjct: 1325 QREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLTEELAQREADNEKLAEDLAQREA 1384
Query: 542 D--EVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN- 712
D ++ E A A ++ + E+ ++E D + L E EA+ + L + + +R A N
Sbjct: 1385 DNEKLTEELAQREADIEKLAEDLAQREADNEK-LAEELAQREADNEKLAEELAQREADNE 1443
Query: 713 -----LDTMDAIHE---EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 868
L +A +E EEL + + D L E+ EA+ EK DL N+
Sbjct: 1444 KLAEELAQREADNEKLAEELAQREADNEKLAEDLAQREADN---EKLTEDLAQREAD-NE 1499
Query: 869 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHND 1030
L +L + A+ + L + EA N L ++ EA+ E+ + EA N +
Sbjct: 1500 KLAEELAQREADNEKLAEELVQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAE 1559
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 1210
EL + + D E + +L +A+ + L +++ E L +L Q+ DNE E
Sbjct: 1560 ELAQREADNEKLTEELAQREADNEKLTEELAQREADNEKLAEDLAQREADNEKLAEELAQ 1619
Query: 1211 LEAVKQGLE----KRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 1378
EAV +G E K + + + ++E + + + L++ +++ + L
Sbjct: 1620 REAVIEGAEADASKTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEG 1679
Query: 1379 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 1558
+ L + ++ E+ E + + ++LE R+ S+ A +ST +
Sbjct: 1680 ENAALAA---LLAAKKAEMVEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRG 1736
Query: 1559 AWMSDCMVPDNWVPFEDL 1612
A + MV +N E L
Sbjct: 1737 ALTA--MVEENQKQVEQL 1752
Score = 93.6 bits (231), Expect = 3e-16
Identities = 119/543 (21%), Positives = 222/543 (40%), Gaps = 21/543 (3%)
Frame = +2
Query: 47 TLNDELLN-----EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDN 211
TLN++L E D++K + D EA + L +A EA L ++L +++ DN
Sbjct: 92 TLNEQLTRALAQREADNEK-LAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADN 150
Query: 212 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILH 391
+ + + + K +E D+ L ++ E + L
Sbjct: 151 EKLAEDLAQREADNEKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLA 210
Query: 392 EELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED------EVL 553
E+L + + D L +DL E + E ++ E+ + L E + E D E+
Sbjct: 211 EDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLTDELA 270
Query: 554 ERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 733
+R A N + + + + E EK L E EA+ + L + +R A N
Sbjct: 271 QREADNEKLAEDLAQREADNEK-----LAEELAQREADNEKLTDELAQREADNEKLA--- 322
Query: 734 HEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQA 913
E+L + + D LTE+ EA+ EK DL N+ L +L + A+ +
Sbjct: 323 --EDLAQREADNEKLTEDLAQREADN---EKLAEDLAQREAD-NEKLTDELAQREADNEK 376
Query: 914 LEKRCSDLEAKNASLTDNQEGHEAEIER------KLEASNLTHNDELHKEKDDKESIMND 1075
L + + EA N LT++ EA+ E+ + EA N ++L + + D E ++ +
Sbjct: 377 LAEDLAQREADNEKLTEDLAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLVEE 436
Query: 1076 LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE----KR 1243
L +A+ + L +++ E L +L Q+ DNE E EAV +G E K
Sbjct: 437 LAQREADNEKLAEELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKT 496
Query: 1244 VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 1423
+ + + ++E + + + L++ +++ + L + L + ++
Sbjct: 497 IEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAA---LLAAK 553
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPF 1603
E+ E + + ++LE R+ S+ A +ST + A + MV +N
Sbjct: 554 KAEMVEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTA--MVEENQKQV 611
Query: 1604 EDL 1612
E L
Sbjct: 612 EQL 614
Score = 93.6 bits (231), Expect = 3e-16
Identities = 115/545 (21%), Positives = 221/545 (40%), Gaps = 8/545 (1%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L +A EA L ++L + D + + D EA + L +A EA L
Sbjct: 1830 EKLTRALAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLA 1889
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
++L +++ DN + + + + K +E D L ++
Sbjct: 1890 EDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLVEELA 1949
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
E + L E+L + + D L+++L E + + ++ E+ + L E + E
Sbjct: 1950 QREADNEKLAEDLAQREADNEKLVEELAQREADNEKLTDELAQREADNEKLAEDLAQREA 2009
Query: 542 DEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
D E+ A +LA +A E E+L + + L E+ EA+ + L + + +R A N
Sbjct: 2010 DN--EKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADN 2067
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL-QRDLD 889
E L + + D L E+ EA+ + + + E I L D L QR+
Sbjct: 2068 EKLA-----ENLAQREADNEKLAEDLAQREADNEKLAENLAQREADIEKLTDELAQRE-- 2120
Query: 890 RVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIM 1069
A+ + L + + EA N L ++ EA+ E+ +E EL + + D E +
Sbjct: 2121 ---ADNEKLAEDLAQREADNEKLAEDLAQREADNEKLVE--------ELAQREADNEKLT 2169
Query: 1070 NDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE---- 1237
++L +A+ + L ++ E L +L Q+ DNE E EAV +G E
Sbjct: 2170 DELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADAS 2229
Query: 1238 KRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 1417
K + + + ++E + + + L++ +++ + L + L +
Sbjct: 2230 KTIEGVYSRCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAA---LLA 2286
Query: 1418 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWV 1597
++ E+ E + + ++LE R+ S+ A +ST + A + MV +N
Sbjct: 2287 AKKAEMVEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTA--MVEENQK 2344
Query: 1598 PFEDL 1612
E L
Sbjct: 2345 QVEQL 2349
Score = 77.8 bits (190), Expect = 2e-11
Identities = 96/419 (22%), Positives = 172/419 (41%), Gaps = 10/419 (2%)
Frame = +2
Query: 386 LHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED------E 547
L E+L + + D L +DL E + E ++ E+ + L E + E D E
Sbjct: 708 LAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLTDE 767
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMD 727
+ +R A N + + + + E EK LVE EA+ + L + +R A N
Sbjct: 768 LAQREADNEKLAEDLAQREADNEK-----LVEELAQREADIEKLTDELAQREADNEKLA- 821
Query: 728 AIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 907
EEL + + D LT+ EA+ EK DL N+ L DL + A+
Sbjct: 822 ----EELAQREADIEKLTDELAQREADN---EKLAEDLAQREAD-NEKLAEDLAQREADN 873
Query: 908 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHV 1087
+ L + + EA N L ++ EA+ E+ E +L + + D E + DL
Sbjct: 874 EKLAEDLAQREADNEKLAEDLAQREADNEKLAE--------DLAQREADNEKLAEDLAQR 925
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE----KRVLDL 1255
+A+ + L +++ E L +L Q+ DNE E EAV +G E K + +
Sbjct: 926 EADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKTIEGV 985
Query: 1256 EATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 1435
+ ++E + + + L++ +++ + L + L + ++ E+
Sbjct: 986 YSRCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAA---LLAAKKAEM 1042
Query: 1436 QEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDL 1612
E + + ++LE R+ S+ A +ST + A + MV +N E L
Sbjct: 1043 VEASDAAGRSVRELESRLSAAVSEASHERAMAEKLISTTRGALTA--MVEENQKQVEQL 1099
Score = 75.5 bits (184), Expect = 9e-11
Identities = 120/583 (20%), Positives = 219/583 (37%), Gaps = 80/583 (13%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L +A EA L DEL + D + + D EA + L ++A EA L
Sbjct: 249 EKLAEDLAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEELAQREADNEKLT 308
Query: 182 DELERKKDDNNAIIKKALDKRISD--LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXI 355
DEL +++ DN + + + + L D QR+ +++ A
Sbjct: 309 DELAQREADNEKLAEDLAQREADNEKLTEDLAQREADNEKLA----------------ED 352
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 535
++ E + L +EL + + D L +DL E + E ++ E+ + L E +
Sbjct: 353 LAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLTEDLAQREADNEKLAEELAQR 412
Query: 536 EEDEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRA 706
E D E+ A +LA +A E EEL + + L E EA+ + L + + +R A
Sbjct: 413 EADN--EKLAEDLAQREADNEKLVEELAQREADNEKLAEELAQREADNEKLAEDLAQREA 470
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
N + + + E E + A ++ EG + + E+ E D L+R+L
Sbjct: 471 DNEKLAEELAQREAVIEGAEADA-SKTIEGVYSRCRELEELAARRELAATGDVDILEREL 529
Query: 887 DRVMAEKQALE------------KRCSDLEAKNA------------SLTDNQEGHEAEIE 994
+ + +ALE K+ +EA +A S ++ HE +
Sbjct: 530 ADALVQLKALEGENAALAALLAAKKAEMVEASDAAGRSVRELESRLSAAVSEASHERAMA 589
Query: 995 RKLEAS-----------NLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSD----- 1126
KL ++ N ++L + D + M + A R++ +++++
Sbjct: 590 EKLISTTRGALTAMVEENQKQVEQLRADHDQARATMQ--AELVAHREMRNARINERLSHP 647
Query: 1127 -------------------------METTYSTLNNELQQKMDDNE----AFLNERDGLEA 1219
E YS +EL + NE A E
Sbjct: 648 ELCDSASPQMPPPNTEVPVAPEIVRSEPLYSVTIDELNKTTTLNEQLTRALAQREADNEK 707
Query: 1220 VKQGLEKRVLDLEATIHDIEM------KTGKDDDYNEAEKQTLKKRISELEEAISILTDK 1381
+ + L +R D E D+ K +D EA+ + L + +++ E I LTD+
Sbjct: 708 LAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLTDE 767
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 1510
+ D ++ + + D K +E E + +LT +L
Sbjct: 768 LAQREADNEKLAEDLAQREADNEKLVEELAQREADIEKLTDEL 810
Score = 74.7 bits (182), Expect = 2e-10
Identities = 115/554 (20%), Positives = 214/554 (38%), Gaps = 52/554 (9%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L +A EA L ++L + D + + D EA + L ++A EA L
Sbjct: 706 EKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEELAQREADIEKLT 765
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
DEL +++ DN + + + + K +E D+ L ++
Sbjct: 766 DELAQREADNEKLAEDLAQREADNEKLVEELAQREADIEKLTDELAQREADNEKLAEELA 825
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
E +I L +EL + + D L +DL E + E ++ E+ + L E + E
Sbjct: 826 QREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREA 885
Query: 542 DEVLERSASNLAIMKAIRE---EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
D E+ A +LA +A E E+L + + L E+ EA+ + L + +R A N
Sbjct: 886 DN--EKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLTDELAQREADN 943
Query: 713 LDTMDAIHEEELRKEKVDKSALTENG--EGCEAEK----QGPEKTVLDLEPTIPSLN--- 865
+ + + E EK+ + EG EA+ +G +LE
Sbjct: 944 EKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKTIEGVYSRCRELEELAARRELAA 1003
Query: 866 ----DALQRDLDRVMAEKQALEKR----CSDLEAKNASLTDNQEGHEAEIERKLEASNLT 1021
D L+R+L + + +ALE + L AK A + + + + R+LE+
Sbjct: 1004 TGDVDILERELADALVQLKALEGENAALAALLAAKKAEMVEASDAAGRSV-RELESRLSA 1062
Query: 1022 HNDELHKEKDDKESIMND-----LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
E E+ E +++ V+ ++ +E +D + +T+ EL +
Sbjct: 1063 AVSEASHERAMAEKLISTTRGALTAMVEENQKQVEQLRADHDQARATMQAELVAHREMRN 1122
Query: 1187 AFLNER-----------------DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD---- 1303
A +NER + V + + TI ++ T ++
Sbjct: 1123 ARINERLSHPELCDSASPQMPPPNTEVPVAPEIVRSEPLYSVTIDELNKTTTLNEQLTRA 1182
Query: 1304 --YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE---- 1465
EA+ + L + +++ E I LTD+ + DI E+ + + D K + E
Sbjct: 1183 LAQREADNEKLAEDLAQREADIEKLTDELAQREADIEKLTDELAQREADNEKLTDELAQR 1242
Query: 1466 KQDLEKRVLELTSK 1507
+ D EK +L +
Sbjct: 1243 EADNEKLAEDLAQR 1256
Score = 73.6 bits (179), Expect = 3e-10
Identities = 120/560 (21%), Positives = 216/560 (38%), Gaps = 55/560 (9%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L ++A EA I L DEL + D + + D EA + L ++A EA L
Sbjct: 748 EKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLVEELAQREADIEKLT 807
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
DEL +++ DN + ++ + K +E D L ++
Sbjct: 808 DELAQREADNEKLAEELAQREADIEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLA 867
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE- 538
E + L E+L + + D L +DL E + E ++ E+ + L E + E
Sbjct: 868 QREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQREA 927
Query: 539 -----EDEVLERSASN--LAIMKAIRE---EELRKEKDGKSALVENG--------EGCEA 664
DE+ +R A N LA A RE E+L +E + A++E EG +
Sbjct: 928 DNEKLTDELAQREADNEKLAEDLAQREADNEKLAEELAQREAVIEGAEADASKTIEGVYS 987
Query: 665 EKQGLEKTVLERRASNLDTMDAIHEE------ELRKEKVDKSAL-----TENGEGCEAEK 811
+ LE+ R + +D + E +L+ + + +AL + E EA
Sbjct: 988 RCRELEELAARRELAATGDVDILERELADALVQLKALEGENAALAALLAAKKAEMVEA-S 1046
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK----------QALEKRCSDLEAKNASLT 961
++V +LE + + + +R MAEK +E+ +E A
Sbjct: 1047 DAAGRSVRELESRLSAA--VSEASHERAMAEKLISTTRGALTAMVEENQKQVEQLRADHD 1104
Query: 962 DNQEGHEAEIERKLEASNLTHNDEL-HKEKDDKES-----------IMNDLDHVKAERQV 1105
+ +AE+ E N N+ L H E D S + ++ + V
Sbjct: 1105 QARATMQAELVAHREMRNARINERLSHPELCDSASPQMPPPNTEVPVAPEIVRSEPLYSV 1164
Query: 1106 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMK 1285
+++ T L L Q+ DNE + EA + L + EA I + +
Sbjct: 1165 TIDELNKTTTLNEQLTRALAQREADNEKLAEDLAQREADIEKLTDELAQREADIEKLTDE 1224
Query: 1286 TGKDDDYNEAEKQTLKKRISELEEAISILTDKA---KKLLKDINIWLSEVTELQEDLNKE 1456
+ + NE L +R ++ E+ L + +KL +D+ ++ +L EDL +
Sbjct: 1225 LAQREADNEKLTDELAQREADNEKLAEDLAQREADNEKLAEDLAQREADNEKLAEDLAQR 1284
Query: 1457 SKEKQDLEKRVLELTSKLEK 1516
+ + L + + + + EK
Sbjct: 1285 EADNEKLAEDLAQREADNEK 1304
>ref|XP_001659192.1| myosin heavy chain, nonmuscle or smooth muscle [Aedes aegypti]
gi|108883254|gb|EAT47479.1| AAEL001411-PA [Aedes aegypti]
Length = 1888
Score = 107 bits (266), Expect = 3e-20
Identities = 131/561 (23%), Positives = 234/561 (41%), Gaps = 57/561 (10%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLN--EKDDKKCIVNDRNILE------AAKQALEYKVADL 157
Q LE + D EA I +E +N + KK +N +++ E AA+Q L+ + L
Sbjct: 843 QELEELMQDLEARIEE-EEERVNALSSEKKKLQINIQDLEEQLEEEEAARQKLQLEKVQL 901
Query: 158 EAAKTTLNDELERKKDDNNAIIK--KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 331
+A + +++ +D N ++K K L++R +DL + +++ A +
Sbjct: 902 DAKLKKMEEDVALTEDQNQKLLKEKKILEERANDLSQTLAEEEEKAKHLAKLKAKHEST- 960
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
++ LE +L H++ Q+ K + ++ K +NE +E +
Sbjct: 961 --------IAELEERLLKDHQQRQESDRSKRKIETEVADL---KEQINERRMQIEEMQQQ 1009
Query: 512 L--KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEK 685
L +E L + + E SA+ A KA RE E S L E E EAEK K
Sbjct: 1010 LIKREEELAQTLVRIDEESAAKAAAQKAQRELE--------SQLAEIQEDLEAEKLARSK 1061
Query: 686 TVLERRASN----------LDTMDAIH-EEELRKEKVDKSALTENGEGCEAEKQGPEKTV 832
++R N LD++D ++ELR ++ + A + + E E E V
Sbjct: 1062 AEKQKRDLNEELEALKNELLDSLDTTAAQQELRSKREQEVATLK--KTLEDESANHEGQV 1119
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD-----NQEGHEAEIER 997
D+ ++ L+ + K LEK LEA+NA L NQ E + R
Sbjct: 1120 SDMRHKHAQEISSINEQLENLKKVKGGLEKAKQTLEAENADLATELRNVNQSRQENDRRR 1179
Query: 998 K---------------LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDME 1132
K +E + + D++ K + + E+I LD + + S+ME
Sbjct: 1180 KQAETQIAELQVKLAEVERARMELQDKVTKLQQESENITQQLDDAELKASAAIKSASNME 1239
Query: 1133 TTYS--------------TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIH 1270
+ + L+++L+Q + EA + + E K+ EK++ +L TI
Sbjct: 1240 SQLTEAQQLLEEETRQKLALSSKLRQLESEKEALQEQLEEDEEAKKNYEKKLAELNFTIQ 1299
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN 1450
+++ ++ +D D ELEEA KK+ KDI + ++ ELQ +
Sbjct: 1300 EMKRRSEEDSDI-----------AKELEEA-------KKKMNKDIEVLQRQILELQATND 1341
Query: 1451 KESKEKQDLEKRVLELTSKLE 1513
+ K K+ ++ + + T +LE
Sbjct: 1342 RLDKSKKKIQSELEDATIELE 1362
Score = 75.9 bits (185), Expect = 7e-11
Identities = 124/567 (21%), Positives = 233/567 (41%), Gaps = 69/567 (12%)
Frame = +2
Query: 23 ADFEATIATLNDELLNEKD-----------------DKKCIVNDRNI-LEAAKQAL---E 139
A E+TIA L + LL + D K +N+R + +E +Q L E
Sbjct: 955 AKHESTIAELEERLLKDHQQRQESDRSKRKIETEVADLKEQINERRMQIEEMQQQLIKRE 1014
Query: 140 YKVA------DLEAAKTTLNDELERKKDDNNAIIKKALD-KRISDLKADAPQRDQEDDMN 298
++A D E+A + +R+ + A I++ L+ ++++ KA+ +RD +++
Sbjct: 1015 EELAQTLVRIDEESAAKAAAQKAQRELESQLAEIQEDLEAEKLARSKAEKQKRDLNEELE 1074
Query: 299 ALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVN 475
AL + S E + L + L+ E + + D+ + ++N
Sbjct: 1075 ALKNELLDSLDTTAAQQELRSKREQEVATLKKTLEDESANHEGQVSDMRHKHAQEISSIN 1134
Query: 476 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI----MKAIREEELRKEKDGKSALVE 643
E + +L+ L E+ + LE ++LA + R+E R+ K ++ + E
Sbjct: 1135 EQLENLKKVKGGL------EKAKQTLEAENADLATELRNVNQSRQENDRRRKQAETQIAE 1188
Query: 644 -NGEGCEAEKQGLEK----TVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAE 808
+ E E+ +E T L++ + N+ + + EL+ KSA + EA+
Sbjct: 1189 LQVKLAEVERARMELQDKVTKLQQESENITQQ--LDDAELKASAAIKSASNMESQLTEAQ 1246
Query: 809 KQGPEKTVLDLEPT-----IPSLNDALQRDLDRVMAEKQALEKRCSDL-----EAKNASL 958
+ E+T L + + S +ALQ L+ K+ EK+ ++L E K S
Sbjct: 1247 QLLEEETRQKLALSSKLRQLESEKEALQEQLEEDEEAKKNYEKKLAELNFTIQEMKRRSE 1306
Query: 959 TDNQEGHEAEIERKLEASNL-----------THNDELHKEKDDKESIMNDLDHVKAERQV 1105
D+ E E +K ++ ND L K K + I ++L+ E +
Sbjct: 1307 EDSDIAKELEEAKKKMNKDIEVLQRQILELQATNDRLDKSK---KKIQSELEDATIELET 1363
Query: 1106 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI--- 1276
+KV D+E + L ++ +E ERD E + E +VL L + +
Sbjct: 1364 QRTKVLDLEKKQKNFDKVLAEEKAVSEQHAQERDAAEREAREKETKVLSLTRELDEAYEK 1423
Query: 1277 --EMKTGKDDDYNEAE-----KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 1435
+++T + NE + + T K + ELE+A L + +L ++ EL
Sbjct: 1424 IDDLETKRKALQNELDELANTQGTADKNVHELEKAKRALESQLAEL-------KAQNEEL 1476
Query: 1436 QEDLNKESKEKQDLEKRVLELTSKLEK 1516
++DL K LE + L ++ E+
Sbjct: 1477 EDDLQLTEDAKLRLEVNMQALRAQFER 1503
Score = 67.8 bits (164), Expect = 2e-08
Identities = 79/332 (23%), Positives = 146/332 (43%), Gaps = 13/332 (3%)
Frame = +2
Query: 593 REEELRKEKDGKSALVENGEGCEAE-KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK 769
+E+ELR+ +D L + + E + +Q +E+ H E + +++
Sbjct: 782 KEDELRQIRDKLDNLSRSSQEYEKKFQQAIEEKT--------------HLAEQLQAEIEL 827
Query: 770 SALTENGEG-CEAEKQGPEKTVLDLEPTIPSLND---ALQRDLDRVMAEKQALEKRCSDL 937
A E G A KQ E+ + DLE I + AL + ++ Q LE++ +
Sbjct: 828 CAEAEEGRARLAARKQELEELMQDLEARIEEEEERVNALSSEKKKLQINIQDLEEQLEEE 887
Query: 938 EAKNASLTDNQEGHEAEIERKLEASNLTH--NDELHKEKDDKESIMNDLDHVKAERQVLE 1111
EA L + +A++++ E LT N +L KEK E NDL AE +
Sbjct: 888 EAARQKLQLEKVQLDAKLKKMEEDVALTEDQNQKLLKEKKILEERANDLSQTLAEEEEKA 947
Query: 1112 SKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 1291
++ ++ + + EL++++ + +R + K+ +E V DL+ I++ M+
Sbjct: 948 KHLAKLKAKHESTIAELEERLLKDH---QQRQESDRSKRKIETEVADLKEQINERRMQI- 1003
Query: 1292 KDDDYNEAEKQTLKKRISELEEAISILTDK------AKKLLKDINIWLSEVTELQEDLNK 1453
E +Q L KR EL + + + ++ A+K +++ S++ E+QEDL
Sbjct: 1004 ------EEMQQQLIKREEELAQTLVRIDEESAAKAAAQKAQRELE---SQLAEIQEDLEA 1054
Query: 1454 ESKEKQDLEKRVLELTSKLEKCICGARDGLST 1549
E + EK+ +L +LE D L T
Sbjct: 1055 EKLARSKAEKQKRDLNEELEALKNELLDSLDT 1086
Score = 67.0 bits (162), Expect = 3e-08
Identities = 115/560 (20%), Positives = 238/560 (42%), Gaps = 56/560 (10%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L+ ++ + +AT ND L +K KK + LE +LE +T +
Sbjct: 1327 EVLQRQILELQAT----NDRL--DKSKKKI-----------QSELEDATIELETQRTKVL 1369
Query: 182 DELERKKDDNNAIIKKALDKRISDLKA---DAPQRDQEDDMNALIXXXXXXXXXXXXXXX 352
D LE+K+ + + ++ A +K +S+ A DA +R+ + ++
Sbjct: 1370 D-LEKKQKNFDKVL--AEEKAVSEQHAQERDAAEREAREKETKVLSLTRELDEAYEK--- 1423
Query: 353 IVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR 532
+ +LE L EL + + + K++ E KR + ++ L++++ L++
Sbjct: 1424 -IDDLETKRKALQNELDELANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQL 1482
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
E+ ++ R N+ ++A E +++ ++ E E +++GL K + +
Sbjct: 1483 TEDAKL--RLEVNMQALRAQFERDVQAKE----------EQSEEKRRGLVKALRD----- 1525
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEG--------CEAEKQGPEKTVLDLEPTIPSLND 868
M+A +EE RK++ A + EG E + E + + + D
Sbjct: 1526 ---MEAELDEE-RKQRAAAVAAKKKLEGDLKDIEATLEMNNKVKEDALKQAKKLQAQVKD 1581
Query: 869 ALQRDLDRVMAEKQAL-------EKRCSDLEAKNASLTDN-------QEGHEAEIERKLE 1006
A+ RD + A K+ L E++ LEA+ L+++ + EAE + LE
Sbjct: 1582 AI-RDAEEAKAAKEELAAVSKEAERKAKALEAEVMQLSEDFASSERARRAAEAERDELLE 1640
Query: 1007 ASNLTHN------DELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQ 1168
N N DE + + ++ +L+ ++ ++L + + T + ELQ
Sbjct: 1641 EINSNSNKGSLMIDEKRRLEARIATLEEELEEEQSNAELLVDRNRKAQITIEQITTELQS 1700
Query: 1169 KMDDNEAFLNERDGLEAVKQGLEKRVLDLE--------ATIHDIEMKTGKDDDYNEAE-K 1321
+ +++ F N + GLE + L+ ++ +LE A + +E K ++ E E K
Sbjct: 1701 EKSNSQKFENVKTGLERQNKELKAKLSELETAQRTKVKAAMASLEAKIANLEEQLENETK 1760
Query: 1322 QTL--KKRISELEEAISILT----------DKAKKLLKDIN----IWLSEVTELQEDLNK 1453
+ L +K +LE+ I LT D+ K+ ++ +N I + E +E++ K
Sbjct: 1761 ERLGGQKANRKLEKKIKELTMNIEDERRHADQYKEQIEKMNNRMKILKRNLDEAEEEIQK 1820
Query: 1454 ESKEKQDLEKRVLELTSKLE 1513
E +K+ ++ ++ E
Sbjct: 1821 EKTQKRKAQREYEDMLESHE 1840
>ref|XP_001659191.1| myosin heavy chain, nonmuscle or smooth muscle [Aedes aegypti]
gi|108883253|gb|EAT47478.1| AAEL001411-PB [Aedes aegypti]
Length = 2001
Score = 107 bits (266), Expect = 3e-20
Identities = 131/561 (23%), Positives = 234/561 (41%), Gaps = 57/561 (10%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLN--EKDDKKCIVNDRNILE------AAKQALEYKVADL 157
Q LE + D EA I +E +N + KK +N +++ E AA+Q L+ + L
Sbjct: 956 QELEELMQDLEARIEE-EEERVNALSSEKKKLQINIQDLEEQLEEEEAARQKLQLEKVQL 1014
Query: 158 EAAKTTLNDELERKKDDNNAIIK--KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 331
+A + +++ +D N ++K K L++R +DL + +++ A +
Sbjct: 1015 DAKLKKMEEDVALTEDQNQKLLKEKKILEERANDLSQTLAEEEEKAKHLAKLKAKHEST- 1073
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
++ LE +L H++ Q+ K + ++ K +NE +E +
Sbjct: 1074 --------IAELEERLLKDHQQRQESDRSKRKIETEVADL---KEQINERRMQIEEMQQQ 1122
Query: 512 L--KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEK 685
L +E L + + E SA+ A KA RE E S L E E EAEK K
Sbjct: 1123 LIKREEELAQTLVRIDEESAAKAAAQKAQRELE--------SQLAEIQEDLEAEKLARSK 1174
Query: 686 TVLERRASN----------LDTMDAIH-EEELRKEKVDKSALTENGEGCEAEKQGPEKTV 832
++R N LD++D ++ELR ++ + A + + E E E V
Sbjct: 1175 AEKQKRDLNEELEALKNELLDSLDTTAAQQELRSKREQEVATLK--KTLEDESANHEGQV 1232
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD-----NQEGHEAEIER 997
D+ ++ L+ + K LEK LEA+NA L NQ E + R
Sbjct: 1233 SDMRHKHAQEISSINEQLENLKKVKGGLEKAKQTLEAENADLATELRNVNQSRQENDRRR 1292
Query: 998 K---------------LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDME 1132
K +E + + D++ K + + E+I LD + + S+ME
Sbjct: 1293 KQAETQIAELQVKLAEVERARMELQDKVTKLQQESENITQQLDDAELKASAAIKSASNME 1352
Query: 1133 TTYS--------------TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIH 1270
+ + L+++L+Q + EA + + E K+ EK++ +L TI
Sbjct: 1353 SQLTEAQQLLEEETRQKLALSSKLRQLESEKEALQEQLEEDEEAKKNYEKKLAELNFTIQ 1412
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN 1450
+++ ++ +D D ELEEA KK+ KDI + ++ ELQ +
Sbjct: 1413 EMKRRSEEDSDI-----------AKELEEA-------KKKMNKDIEVLQRQILELQATND 1454
Query: 1451 KESKEKQDLEKRVLELTSKLE 1513
+ K K+ ++ + + T +LE
Sbjct: 1455 RLDKSKKKIQSELEDATIELE 1475
Score = 75.9 bits (185), Expect = 7e-11
Identities = 124/567 (21%), Positives = 233/567 (41%), Gaps = 69/567 (12%)
Frame = +2
Query: 23 ADFEATIATLNDELLNEKD-----------------DKKCIVNDRNI-LEAAKQAL---E 139
A E+TIA L + LL + D K +N+R + +E +Q L E
Sbjct: 1068 AKHESTIAELEERLLKDHQQRQESDRSKRKIETEVADLKEQINERRMQIEEMQQQLIKRE 1127
Query: 140 YKVA------DLEAAKTTLNDELERKKDDNNAIIKKALD-KRISDLKADAPQRDQEDDMN 298
++A D E+A + +R+ + A I++ L+ ++++ KA+ +RD +++
Sbjct: 1128 EELAQTLVRIDEESAAKAAAQKAQRELESQLAEIQEDLEAEKLARSKAEKQKRDLNEELE 1187
Query: 299 ALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVN 475
AL + S E + L + L+ E + + D+ + ++N
Sbjct: 1188 ALKNELLDSLDTTAAQQELRSKREQEVATLKKTLEDESANHEGQVSDMRHKHAQEISSIN 1247
Query: 476 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI----MKAIREEELRKEKDGKSALVE 643
E + +L+ L E+ + LE ++LA + R+E R+ K ++ + E
Sbjct: 1248 EQLENLKKVKGGL------EKAKQTLEAENADLATELRNVNQSRQENDRRRKQAETQIAE 1301
Query: 644 -NGEGCEAEKQGLEK----TVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAE 808
+ E E+ +E T L++ + N+ + + EL+ KSA + EA+
Sbjct: 1302 LQVKLAEVERARMELQDKVTKLQQESENITQQ--LDDAELKASAAIKSASNMESQLTEAQ 1359
Query: 809 KQGPEKTVLDLEPT-----IPSLNDALQRDLDRVMAEKQALEKRCSDL-----EAKNASL 958
+ E+T L + + S +ALQ L+ K+ EK+ ++L E K S
Sbjct: 1360 QLLEEETRQKLALSSKLRQLESEKEALQEQLEEDEEAKKNYEKKLAELNFTIQEMKRRSE 1419
Query: 959 TDNQEGHEAEIERKLEASNL-----------THNDELHKEKDDKESIMNDLDHVKAERQV 1105
D+ E E +K ++ ND L K K + I ++L+ E +
Sbjct: 1420 EDSDIAKELEEAKKKMNKDIEVLQRQILELQATNDRLDKSK---KKIQSELEDATIELET 1476
Query: 1106 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI--- 1276
+KV D+E + L ++ +E ERD E + E +VL L + +
Sbjct: 1477 QRTKVLDLEKKQKNFDKVLAEEKAVSEQHAQERDAAEREAREKETKVLSLTRELDEAYEK 1536
Query: 1277 --EMKTGKDDDYNEAE-----KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTEL 1435
+++T + NE + + T K + ELE+A L + +L ++ EL
Sbjct: 1537 IDDLETKRKALQNELDELANTQGTADKNVHELEKAKRALESQLAEL-------KAQNEEL 1589
Query: 1436 QEDLNKESKEKQDLEKRVLELTSKLEK 1516
++DL K LE + L ++ E+
Sbjct: 1590 EDDLQLTEDAKLRLEVNMQALRAQFER 1616
Score = 67.8 bits (164), Expect = 2e-08
Identities = 79/332 (23%), Positives = 146/332 (43%), Gaps = 13/332 (3%)
Frame = +2
Query: 593 REEELRKEKDGKSALVENGEGCEAE-KQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK 769
+E+ELR+ +D L + + E + +Q +E+ H E + +++
Sbjct: 895 KEDELRQIRDKLDNLSRSSQEYEKKFQQAIEEKT--------------HLAEQLQAEIEL 940
Query: 770 SALTENGEG-CEAEKQGPEKTVLDLEPTIPSLND---ALQRDLDRVMAEKQALEKRCSDL 937
A E G A KQ E+ + DLE I + AL + ++ Q LE++ +
Sbjct: 941 CAEAEEGRARLAARKQELEELMQDLEARIEEEEERVNALSSEKKKLQINIQDLEEQLEEE 1000
Query: 938 EAKNASLTDNQEGHEAEIERKLEASNLTH--NDELHKEKDDKESIMNDLDHVKAERQVLE 1111
EA L + +A++++ E LT N +L KEK E NDL AE +
Sbjct: 1001 EAARQKLQLEKVQLDAKLKKMEEDVALTEDQNQKLLKEKKILEERANDLSQTLAEEEEKA 1060
Query: 1112 SKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG 1291
++ ++ + + EL++++ + +R + K+ +E V DL+ I++ M+
Sbjct: 1061 KHLAKLKAKHESTIAELEERLLKDH---QQRQESDRSKRKIETEVADLKEQINERRMQI- 1116
Query: 1292 KDDDYNEAEKQTLKKRISELEEAISILTDK------AKKLLKDINIWLSEVTELQEDLNK 1453
E +Q L KR EL + + + ++ A+K +++ S++ E+QEDL
Sbjct: 1117 ------EEMQQQLIKREEELAQTLVRIDEESAAKAAAQKAQRELE---SQLAEIQEDLEA 1167
Query: 1454 ESKEKQDLEKRVLELTSKLEKCICGARDGLST 1549
E + EK+ +L +LE D L T
Sbjct: 1168 EKLARSKAEKQKRDLNEELEALKNELLDSLDT 1199
Score = 67.0 bits (162), Expect = 3e-08
Identities = 115/560 (20%), Positives = 238/560 (42%), Gaps = 56/560 (10%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L+ ++ + +AT ND L +K KK + LE +LE +T +
Sbjct: 1440 EVLQRQILELQAT----NDRL--DKSKKKI-----------QSELEDATIELETQRTKVL 1482
Query: 182 DELERKKDDNNAIIKKALDKRISDLKA---DAPQRDQEDDMNALIXXXXXXXXXXXXXXX 352
D LE+K+ + + ++ A +K +S+ A DA +R+ + ++
Sbjct: 1483 D-LEKKQKNFDKVL--AEEKAVSEQHAQERDAAEREAREKETKVLSLTRELDEAYEK--- 1536
Query: 353 IVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR 532
+ +LE L EL + + + K++ E KR + ++ L++++ L++
Sbjct: 1537 -IDDLETKRKALQNELDELANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQL 1595
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
E+ ++ R N+ ++A E +++ ++ E E +++GL K + +
Sbjct: 1596 TEDAKL--RLEVNMQALRAQFERDVQAKE----------EQSEEKRRGLVKALRD----- 1638
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEG--------CEAEKQGPEKTVLDLEPTIPSLND 868
M+A +EE RK++ A + EG E + E + + + D
Sbjct: 1639 ---MEAELDEE-RKQRAAAVAAKKKLEGDLKDIEATLEMNNKVKEDALKQAKKLQAQVKD 1694
Query: 869 ALQRDLDRVMAEKQAL-------EKRCSDLEAKNASLTDN-------QEGHEAEIERKLE 1006
A+ RD + A K+ L E++ LEA+ L+++ + EAE + LE
Sbjct: 1695 AI-RDAEEAKAAKEELAAVSKEAERKAKALEAEVMQLSEDFASSERARRAAEAERDELLE 1753
Query: 1007 ASNLTHN------DELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQ 1168
N N DE + + ++ +L+ ++ ++L + + T + ELQ
Sbjct: 1754 EINSNSNKGSLMIDEKRRLEARIATLEEELEEEQSNAELLVDRNRKAQITIEQITTELQS 1813
Query: 1169 KMDDNEAFLNERDGLEAVKQGLEKRVLDLE--------ATIHDIEMKTGKDDDYNEAE-K 1321
+ +++ F N + GLE + L+ ++ +LE A + +E K ++ E E K
Sbjct: 1814 EKSNSQKFENVKTGLERQNKELKAKLSELETAQRTKVKAAMASLEAKIANLEEQLENETK 1873
Query: 1322 QTL--KKRISELEEAISILT----------DKAKKLLKDIN----IWLSEVTELQEDLNK 1453
+ L +K +LE+ I LT D+ K+ ++ +N I + E +E++ K
Sbjct: 1874 ERLGGQKANRKLEKKIKELTMNIEDERRHADQYKEQIEKMNNRMKILKRNLDEAEEEIQK 1933
Query: 1454 ESKEKQDLEKRVLELTSKLE 1513
E +K+ ++ ++ E
Sbjct: 1934 EKTQKRKAQREYEDMLESHE 1953
>ref|XP_001581403.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121915630|gb|EAY20417.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 4263
Score = 106 bits (264), Expect = 5e-20
Identities = 130/535 (24%), Positives = 226/535 (42%), Gaps = 32/535 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
LEN + E + L E N + +K ++ + LE KQ LE + +LE K L +E
Sbjct: 2192 LENAKSQLENEKSQLIQEKTNLEQEKAQLLEQKKNLEEEKQKLETEKTNLEQEKAKLIEE 2251
Query: 188 ---LERKK-----------DDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXX 325
LE++K + +I++ + K + + E + LI
Sbjct: 2252 KTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNL 2311
Query: 326 XXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES-K 502
+NLE L EE + +K LI++ E K + E ++LE K
Sbjct: 2312 EQEKAKPIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEK 2371
Query: 503 SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL- 679
++ ++E E+E L +NL KA EE + K+ L+E E EK L
Sbjct: 2372 AKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLI 2431
Query: 680 -EKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIP 856
EKT LE+ S L EEE ++ + +K+ L E+ E EK + +LE
Sbjct: 2432 EEKTNLEQEKSQLLDQKKNLEEEKQRLETEKAKLIEDKTNLEQEKAQLLEQKKNLEEEKA 2491
Query: 857 SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDEL 1036
L + + + + Q +E S + K L+ + + S + N E
Sbjct: 2492 KLEEEKAQAQKTIEEKDQEIEDLTSQINVKTKDLSLLESDFNNMSFTNADQSTMISNYE- 2550
Query: 1037 HKEKDDKESIMNDLDH----VKAERQVLESKVSDM------ETTYSTLNNELQQKMDDNE 1186
KE DK +NDL + + R L+SK + + L + L+QK +NE
Sbjct: 2551 -KELSDKNKEINDLQNQLKQMTQNRDELQSKSDKLNEEIEEKKNIQNLESSLEQKNKENE 2609
Query: 1187 AF---LNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 1354
LN+ G L A Q + + +L +D++ K+ + N E LKK ++E +
Sbjct: 2610 DLKQQLNKTQGELSAQLQQKTQELENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERD 2669
Query: 1355 EAIS-ILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ IS +L ++ +L K ++ +E T L+ +++ E +L+K V + +++ +
Sbjct: 2670 KKISQLLENEVNELKKKLSDKENENTSLKNTISERENEINNLKKNVSDKENEINQ 2724
Score = 95.9 bits (237), Expect = 7e-17
Identities = 127/541 (23%), Positives = 217/541 (40%), Gaps = 39/541 (7%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q LE + + E A L +E N + +K ++ ++ LE K L + +LE K L
Sbjct: 2232 QKLETEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLI 2291
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+E + + +I++ + K + + E + LI +
Sbjct: 2292 EEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKT 2351
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES-KSRSLKEHFLREE 538
NLE L EE + +K LI++ E K + E ++LE K++ ++E E+
Sbjct: 2352 NLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQ 2411
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE--KTVLERRASN 712
E L +NL KA EE + KS L++ + E EKQ LE K L +N
Sbjct: 2412 EKAKLIEEKTNLEQEKAKLIEEKTNLEQEKSQLLDQKKNLEEEKQRLETEKAKLIEDKTN 2471
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQ---RD 883
L E+E + K L E E EK +KT+ + + I L + +D
Sbjct: 2472 L-------EQEKAQLLEQKKNLEEEKAKLEEEKAQAQKTIEEKDQEIEDLTSQINVKTKD 2524
Query: 884 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN--------LTHN---- 1027
L LE +++ NA + +E E+ K + N +T N
Sbjct: 2525 LS-------LLESDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQNRDEL 2577
Query: 1028 ----DELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 1195
D+L++E ++K++I N ++ + + E + T L+ +LQQK + E
Sbjct: 2578 QSKSDKLNEEIEEKKNIQNLESSLEQKNKENEDLKQQLNKTQGELSAQLQQKTQELENLT 2637
Query: 1196 NERDGLEAVKQ-----------GLEKRVLDLEATIHDI------EMKTGKDDDYNEAEKQ 1324
E + L+ + L+K V + + I + E+K D NE
Sbjct: 2638 KEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVNELKKKLSDKENE--NT 2695
Query: 1325 TLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
+LK ISE E I+ L +IN + +T + +LNK E+ K+++
Sbjct: 2696 SLKNTISERENEINNLKKNVSDKENEINQLKNNLTMRETELNKMKDEEVKNAKQIIAQKD 2755
Query: 1505 K 1507
K
Sbjct: 2756 K 2756
Score = 82.0 bits (201), Expect = 1e-12
Identities = 118/582 (20%), Positives = 241/582 (41%), Gaps = 23/582 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDD----KKCIVNDRNILEAAKQALEYKVADLEAAKTT 175
L+N++ + T+A + E+ K++ K+ I N+ N +E K+ + + A++E K T
Sbjct: 1534 LQNEIEQHKQTMAERDAEIQKNKEEIEQQKQTISNNNNEIEQLKKTISERDAEIEQLKKT 1593
Query: 176 LNDELERKKDDNNAIIK-----KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 340
+ + E K N I + D I LK QRDQ +
Sbjct: 1594 IAERDESIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQRDQTIAEKEDLIKQLQSEIEQH 1653
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAA-EPGKRTVNEIVSHLESKSRSLK 517
N E+ E+L++ + + IK L + E K+T+ E + ++ ++
Sbjct: 1654 KQTISDKNNEI------EQLKQTVNARDEAIKQLQSEIEQHKQTIAERDAEIQKNKEEIE 1707
Query: 518 EHFLR-EEEDEVLERSASNLAIMKAI---REEELRKEKDGKSALVENGEGCEAEKQGLEK 685
+ + DE +++ + + K R+ E+ + K V+ + AEK+ L K
Sbjct: 1708 QQKQTISQRDETIKQLQNEIEQHKQTISQRDAEIEQLKQ----TVQQSDQTIAEKEDLIK 1763
Query: 686 TV---LERRASNLDTMDAI---HEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEP 847
+ +E+ + DA ++EE+ ++K S E+ + ++E + ++T+ D E
Sbjct: 1764 QLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDESIKQMQSEIEQNKQTIADREK 1823
Query: 848 TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHN 1027
I + + + ++ +E+ + ++A + N+E EI++K EA N N
Sbjct: 1824 EIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKE----EIQQKNEAINALTN 1879
Query: 1028 DELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
E ++K + +L+ A + L +KV ++ + S LN L+ +
Sbjct: 1880 -----EGEEKRLKILELE---ANNENLINKVKELNDSVSDLN-------------LSTEN 1918
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTG---KDDDYNEAEKQTLKKRISELEEAISILTD 1378
VKQ + + DL IH++E+K+ K + + E Q+L ++ EE I L +
Sbjct: 1919 QNSVVKQ-MTDEIKDLNKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELIKKLQE 1977
Query: 1379 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKE 1558
+ + L N + LQE + ++ K E + + +++ + TIK
Sbjct: 1978 EVENLTNTKNQNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKN 2037
Query: 1559 AWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 1684
+ + E+ ++ + L TK + I +
Sbjct: 2038 LQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKK 2079
Score = 79.7 bits (195), Expect = 5e-12
Identities = 105/531 (19%), Positives = 235/531 (44%), Gaps = 39/531 (7%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYK--VADLEAAKTTLN 181
+++++ + TIA E+ E+ + D +I + ++ ++K +A+ +A
Sbjct: 1807 MQSEIEQNKQTIADREKEI--EQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNK 1864
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+E+++K + NA+ + +KR+ L+ +A + + + L +V
Sbjct: 1865 EEIQQKNEAINALTNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQNSVVK 1924
Query: 362 NLEVNILILHEEL----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
+ I L++++ QK+ ++K I+ L K E++ L+ + +
Sbjct: 1925 QMTDEIKDLNKQIHELEVKSENQQKQIEEKDKEIQSLTNT---KAQNEELIKKLQEEVEN 1981
Query: 512 LKEHFLREEED-EVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT 688
L + EE + L+ +L K E+ ++K+++ +L E + L++
Sbjct: 1982 LTNTKNQNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQ 2041
Query: 689 V---LERRASNLDTMD-------------AIHEEELRKEKVDKSALTENGEGCEAEKQGP 820
V E +A+N +T+ A +EE+++K++ + +L+ K
Sbjct: 2042 VQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNT-------KNEN 2094
Query: 821 EKTVLDLEPTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAK----NASLTDNQEGH 979
E+ + L+ I +L + + + ++ E Q L+K+ ++ + K NA L+
Sbjct: 2095 EELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSS 2154
Query: 980 EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNE 1159
+ + + A N ++L K+ ++K+++++ L+ K+SD+E S L NE
Sbjct: 2155 DELTTKFINAQN--EINQLTKQNNEKDNLISQLNQ----------KISDLENAKSQLENE 2202
Query: 1160 LQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGK--DDDYN-EAEKQTL 1330
Q + + E+ L K+ LE+ LE ++E + K ++ N E EK L
Sbjct: 2203 KSQLIQEKTNLEQEKAQLLEQKKNLEEEKQKLETEKTNLEQEKAKLIEEKTNLEQEKAKL 2262
Query: 1331 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEK 1483
+ + LE+ + L ++ L ++ + E T L+++ K +EK +LE+
Sbjct: 2263 IEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQ 2313
Score = 71.6 bits (174), Expect = 1e-09
Identities = 75/366 (20%), Positives = 177/366 (48%), Gaps = 16/366 (4%)
Frame = +2
Query: 467 TVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNLAIMKAIR-------EEELRKEK 619
T+ + +++K LK+ L E+++ + A +++I AI E E+ EK
Sbjct: 1298 TIKNQANIIKAKDDDLKQTKEILEYREEQIEKFIAESVSIRDAIETLKQRISELEMLLEK 1357
Query: 620 DGKSALVENGEGCEAEKQGLEKTV--LERRASNLDTMDA---IHEEELRKEKVDKSALTE 784
K + E E +Q LE+ L+ +++ ++ ++E+E+ ++ +T
Sbjct: 1358 KDKENNDKIAEIQEENRQTLEQLAKQLQEAEEDINVLEGNCQVYEQEIAEKDKQIEQMTN 1417
Query: 785 NGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD 964
+ + E T+ L+ + + + +++ V ++ +++ +D+E K+A +
Sbjct: 1418 DIKSLEEVINEQSNTIDSLKQDVATKEEEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQK 1477
Query: 965 NQEGHEAEIERKLEASNLTHNDELHKE-KDDKESIMNDLDHVKAERQVLESKVSDMETTY 1141
N+E EIE+ ++ DE K+ + + E + E + L++ +S+ E T
Sbjct: 1478 NKE----EIEQ--HKQTISQRDETIKQLQSEIEQHKQTIADKNNEIEQLKNTISEREETI 1531
Query: 1142 STLNNELQQKMDDNEAFLNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
L NE++Q ++ + ERD ++ K+ +E++ + ++IE + K +AE
Sbjct: 1532 KQLQNEIEQ----HKQTMAERDAEIQKNKEEIEQQKQTISNNNNEIE-QLKKTISERDAE 1586
Query: 1319 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 1498
+ LKK I+E +E+I L ++ ++ + I+ +E+ +L++ + + + + E + +L
Sbjct: 1587 IEQLKKTIAERDESIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQRDQTIAEKEDLIKQL 1646
Query: 1499 TSKLEK 1516
S++E+
Sbjct: 1647 QSEIEQ 1652
Score = 69.3 bits (168), Expect = 7e-09
Identities = 112/562 (19%), Positives = 224/562 (39%), Gaps = 84/562 (14%)
Frame = +2
Query: 62 LLNEKDDKKCIVNDRN-ILEAAKQALEYKVADLEAAKTTLNDELERKKDDNN-------- 214
L + D K I+N + + +Q+L+ +++A K L +L+ K+ N
Sbjct: 3234 LSTDMDSKNKIINQQEQTIIGLEQSLKVSKNEVDATKRELQKQLQNNKELQNQIKMTKEQ 3293
Query: 215 ---------AIIKKALDK--RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+++KK DK RI L + P Q + +N I I++
Sbjct: 3294 FAKLEAKLQSVVKKLNDKDQRIDSLMSSDPNNKQTNQLNKQISDLNLENEKLKTRVDIIT 3353
Query: 362 --NLEVNILILHEELQKEKDD------KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK 517
N + + ++ QK K D KT LI + K + E++ + K++ +
Sbjct: 3354 RENQSLKDDLESQKSQKSKLDESCNALKTELINKKSIMDQYKEKLKELMEQINLKNKQIS 3413
Query: 518 E--------------HFLR--EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG 649
E +++ E+E E+ E K + ++++ K D + L E+
Sbjct: 3414 ELKAEFNGSDDEDRKSYVKVIEQEGEITELKVIIDRQKKFVGQQKM-KIADLEKNLKESN 3472
Query: 650 EGCEAEKQGLEKTV--LERRASNLD---------------TMDAIHEE-ELRKEKVDKSA 775
+ + + L+ T+ LE R NL+ T++ +++E E K K+D +
Sbjct: 3473 DEAQKMTKNLQTTIYELEDRCQNLNQTIEMKNFRLRENEKTIEDLNKEIEFLKGKIDILS 3532
Query: 776 LTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALE---KRCSDLEAK 946
+ + K ++ L+ T+ ++ L D + +LE K +++ K
Sbjct: 3533 REISMYSDNSSKDNLISKIVSLQKTVSEKDEQLN---DAKINSNNSLEIEDKMQQEIDQK 3589
Query: 947 NASLTDNQEGHEAEIERKLEASNLTHND---------ELHKEKDDKESIMNDLDHVKAER 1099
N+ + H E + ++ + +H + +L K ++ ND ++ E
Sbjct: 3590 NSRI------HHLENQMRVLLNKASHENAKEESKVKIDLKKANVKLSNLENDFSSLQEEN 3643
Query: 1100 QVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIE 1279
L+SKVS +E +E+ N +NE I +++
Sbjct: 3644 AALKSKVSKLELVIKEKQSEINIMAQKNNNDINE---------------------ISELK 3682
Query: 1280 MKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQED-- 1444
K K ++ EK + +K+ SE+++ + L K +L +I I S++ +LQ+D
Sbjct: 3683 SKLRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELDDSKSEIRILKSKINQLQQDFD 3742
Query: 1445 -----LNKESKEKQDLEKRVLE 1495
L KES++ LE+++ E
Sbjct: 3743 AKNHSLQKESEKLSQLEEKMKE 3764
Score = 65.1 bits (157), Expect = 1e-07
Identities = 109/531 (20%), Positives = 227/531 (42%), Gaps = 31/531 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDD---KKCIVNDR--------NILEAAKQALEYKVAD 154
L++++ + TIA + E+ K++ +K ++ R N +E KQ + + A+
Sbjct: 1681 LQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDETIKQLQNEIEQHKQTISQRDAE 1740
Query: 155 LEAAKTTL--NDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 328
+E K T+ +D+ +K+D + K L I K +RD E N
Sbjct: 1741 IEQLKQTVQQSDQTIAEKED----LIKQLQSEIEQHKQTIAERDAEIQKNK--------- 1787
Query: 329 XXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
+S + +I + E+++ K K++ E K+T+ E + ++
Sbjct: 1788 EEIEQQKQTISQRDESIKQMQSEIEQNKQTIADREKEI---EQHKQTIAERDNSIKQLQE 1844
Query: 509 SLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT 688
+++H + + ER A I K +EE++++ + +AL GE EK+
Sbjct: 1845 EIEQH-----KQTIAERDAE---IQK--NKEEIQQKNEAINALTNEGE----EKR---LK 1887
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 868
+LE A+N + ++ + +EL D + TEN V + I LN
Sbjct: 1888 ILELEANNENLINKV--KELNDSVSDLNLSTEN----------QNSVVKQMTDEIKDLN- 1934
Query: 869 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL--EASNLTHNDELHK 1042
+ + + + + +K+ + + + SLT+ + +E E+ +KL E NLT+ ++
Sbjct: 1935 ---KQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNE-ELIKKLQEEVENLTNTKNQNE 1990
Query: 1043 E--KDDKESIMN-------DLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 1195
E K+ +E + + + D +K +++ ++S + T+ N +Q E
Sbjct: 1991 ETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKA 2050
Query: 1196 NERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILT 1375
+ ++ + QG + + + +AT + K ++ K ++ I +L+E I LT
Sbjct: 2051 TNEETIKKL-QGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQEEIQNLT 2109
Query: 1376 -------DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 1507
++ KKL ++I + E + +N+ + + L ELT+K
Sbjct: 2110 NTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTK 2160
>ref|XP_653447.1| Viral A-type inclusion protein repeat [Entamoeba histolytica
HM-1:IMSS] gi|56470397|gb|EAL48061.1| Viral A-type
inclusion protein repeat, putative [Entamoeba histolytica
HM-1:IMSS]
Length = 1813
Score = 105 bits (262), Expect = 8e-20
Identities = 125/583 (21%), Positives = 256/583 (43%), Gaps = 67/583 (11%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
+ KV E L D++ NE D + + ++ K+++ ++ + K ++N+EL
Sbjct: 218 KKKVEILENEKKDLIDKMANENDGMSKLNEELTQIKNEKESINNELIQTKQEKESINNEL 277
Query: 191 ERKKDDN----NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIV 358
+ K DN N + + +K K + + + E MN L +
Sbjct: 278 TQLKTDNDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNEL--------------SQLK 323
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--LR 532
E L E+++K +++K+ LI +L G +NE ++ + + + ++
Sbjct: 324 QEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNELNSIK 383
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
EE+ + E + K I+EE+ + E++ K L E E EK+G L+ +
Sbjct: 384 EEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKE----IEKEKEG--NNQLQNEINT 437
Query: 713 LDT-MDAIHE----------EELRKEKVDKSALTENGEGCEAEKQGPE---KTVLDLEPT 850
+ T M I E +E+ K K ++ L + + EKQ E ++D++
Sbjct: 438 IQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQ 497
Query: 851 IPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHND 1030
+ + L+ + +++ EK +E + + + LT+ +E + E++ ++A N T
Sbjct: 498 KENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELD-SIKADNSTKEL 556
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL------QQKMDDNEAF 1192
E++K ++K + ND D V+ E++ ++ +++ ++ S EL +Q+++D +A
Sbjct: 557 EINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAK 616
Query: 1193 L-----NERDGLEAVKQGLEKRVLDLEATIHDI-EMKTGKDDDYNEAEKQTLKKRISELE 1354
L N DGL + + ++K + E +++ ++K +D+ NE K K+ I + E
Sbjct: 617 LITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNK--TKEEIKQKE 674
Query: 1355 EAISILTDKAKKLLKDINIWL------------------SEVTELQED-------LNKES 1459
L ++ LL ++N +E+T+L ED LN+
Sbjct: 675 NETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIK 734
Query: 1460 KEKQDLE----------KRVLELTSKLEKCICGARDGLSTIKE 1558
EKQ++E +++ + SKL + DG+S + E
Sbjct: 735 TEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNE 777
Score = 103 bits (256), Expect = 4e-19
Identities = 115/559 (20%), Positives = 249/559 (44%), Gaps = 69/559 (12%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L +K+A+ ++ LN+EL K++K+ I N+ + K+++ ++ L+ +E
Sbjct: 231 LIDKMANENDGMSKLNEELTQIKNEKESINNELIQTKQEKESINNELTQLKTDNDQKENE 290
Query: 188 LERKKDDNNAIIKKALDKRISDLKA----DAPQRDQEDDMNALIXXXXXXXXXXXXXXXI 355
L + + + + +I+K + + K ++++E+ N L
Sbjct: 291 LNQVRHEKDEVIEKFNTSKEENEKIMNELSQLKQEKEEKENELKEQVKKMEEEKSKLITE 350
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--L 529
+SN I L+EEL + K +K + +L + + K+ + E + + ++++ +KE +
Sbjct: 351 LSNGSDGISKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKI 410
Query: 530 REEEDEVL-----ERSASNL---------AIMKAIREE----------ELRKEKDGKSAL 637
EE+ E+L E+ +N MK I E+ E+ K K+ + L
Sbjct: 411 EEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENL 470
Query: 638 VENGEGCEAEKQGLEKT---VLERRASNLDTMDAIHEE--ELRKEKV-----------DK 769
+ + EKQ E +++ + + ++ + EE ++ EK +K
Sbjct: 471 QKELNQIKEEKQKTENEKNELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEK 530
Query: 770 SALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA---LQRDLDRVMAEKQALEKRCSDLE 940
+ LTE E + E + E I +N+ LQ D D V EK+ ++K + ++
Sbjct: 531 NKLTEEKESIKQELDSIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIK 590
Query: 941 AKNASLTDN-----QEGHEAEIERKLEASNLTH--------NDELHKEKDDKESIMNDLD 1081
+ + + +E + E E+ +++ + N+ + K KD+KE+I N+L+
Sbjct: 591 IEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELN 650
Query: 1082 HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL--EKRVLDL 1255
+K ER + ++ + + NE Q ++ LNE + ++ KQ + EK V+
Sbjct: 651 QIKNERDNISNEFNKTKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQ 710
Query: 1256 EATIHDIEMKTGKDDDYNE-----AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 1420
E ++ K NE EKQ ++ +++ ++ + D+ KL+ +++
Sbjct: 711 EKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELSNGND 770
Query: 1421 EVTELQEDLNKESKEKQDL 1477
+++L E+L + +EK+++
Sbjct: 771 GISKLNEELTQTKQEKENV 789
Score = 102 bits (253), Expect = 9e-19
Identities = 106/505 (20%), Positives = 231/505 (45%), Gaps = 19/505 (3%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNI---LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
L+ +N ++ KK ++ +N + K +E + + T+N+ELE+ K + N +
Sbjct: 1124 LSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNKKELNDL 1183
Query: 221 IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEEL 400
K D I +L + +D++N+LI +NL+ L E++
Sbjct: 1184 QTK-YDNEILELNKN------KDELNSLI-----------------NNLKEEKTNLEEQV 1219
Query: 401 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--LREEEDEVLERSASNL 574
+K +++K+ LI +L G +NE ++ + + + ++EE+ + E +
Sbjct: 1220 KKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQII 1279
Query: 575 AIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT----MDAIHEE 742
K I+EE+ + E++ K L E E EK+G L+ + + T ++ ++E
Sbjct: 1280 NENKEIKEEKEKIEEEKKELLKE----IEKEKEG--NNQLQNEINTIQTRMKEIEEKNQE 1333
Query: 743 ELRKEKVDKSALTENGEGCEAE----KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 910
+ + + E E + E K+ K + DL L+ L +++ + EK+
Sbjct: 1334 IICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLS-KLNEEIETINKEKE 1392
Query: 911 ALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTH-----NDELHKEKDDKESIMN 1072
+ K L+ +N + D E E+ + K E L H ND +++ +D I N
Sbjct: 1393 GIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKN 1452
Query: 1073 DLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 1252
D + + + L+++++ +++ L+N L + E + + A+K+ ++ V
Sbjct: 1453 DKEELTEKNVQLQNEINKLKSENEELSNNLS---FEKEGLKQVNEEVNAIKEERDELVKQ 1509
Query: 1253 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 1432
++ I + + K ++ ++N +E +I+ +E ++ ++ K+ LK++ + E+
Sbjct: 1510 IK-KIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIE- 1567
Query: 1433 LQEDLNKESKEKQDLEKRVLELTSK 1507
QE + E K+K++L++ E+T K
Sbjct: 1568 -QEKESNEIKKKEELQELQEEITEK 1591
Score = 100 bits (249), Expect = 3e-18
Identities = 120/581 (20%), Positives = 253/581 (43%), Gaps = 77/581 (13%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 226
+N+EL + K++KK I ++N + + ++ + +E K L E+E++K+ NN +
Sbjct: 375 INNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE 434
Query: 227 --------KALDKRISDLKAD---------APQRDQEDDMNALIXXXXXXXXXXXXXXXI 355
K ++++ ++ D Q + + ++N + +
Sbjct: 435 INTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDV 494
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDL--VAAEPGKRTVN------------------ 475
+ E + L EE ++ ++KT + L + E K T
Sbjct: 495 KTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTK 554
Query: 476 --EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEK---------- 619
EI E K++ ++ ++E E +++ + + I K+ +EEEL K K
Sbjct: 555 ELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEK 614
Query: 620 -----------DGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEK 760
DG + L E + + EK+ + E ++ N+ +EE+++++
Sbjct: 615 AKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKE 674
Query: 761 -------VDKSALTENGEGCEAEKQ--GPEKTVL--DLEPTIPSLND---ALQRDLDRVM 898
+KS L + EKQ EK V+ + E I LN+ ++ +L+++
Sbjct: 675 NETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIK 734
Query: 899 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDL 1078
EKQ +E + + + + D + E+ + + N+EL + K +KE+++N+L
Sbjct: 735 TEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKL-NEELTQTKQEKENVLNEL 793
Query: 1079 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 1258
+ +K E + + + E NN++QQ+++ NE LE K + +L
Sbjct: 794 NQIKNEFASFKEQNTQKENELKDENNKVQQELEQKN---NEVSKLEEEKGNISN---ELS 847
Query: 1259 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 1438
T ++E K K + +++ K+ +EL+E + + ++ KL+ +++ +++L
Sbjct: 848 NTKQELEQK--KQEIITITQEKEEKE--NELKEQVKKIEEEKSKLITELSNGSDGISKLN 903
Query: 1439 EDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEA 1561
E+L + +EK++++K + E KLE+ L IKEA
Sbjct: 904 EELTQTKQEKEEIQKALEEEKEKLER----IETELKEIKEA 940
Score = 93.6 bits (231), Expect = 3e-16
Identities = 106/517 (20%), Positives = 236/517 (45%), Gaps = 29/517 (5%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKK 229
+N+EL + K++KK I ++N + + ++ + +E K L E+E++K+ NN + +
Sbjct: 1257 INNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE 1316
Query: 230 ALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKE 409
I + +++QE ++ + L +EL +
Sbjct: 1317 I--NTIQTRMKEIEEKNQE---------------IICDNNKEIAKFKEEQENLQKELNQI 1359
Query: 410 KDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF--LREEEDEV---LERSASNL 574
K++K+ LI DL G +NE + + + +++ L+EE +++ LE+ L
Sbjct: 1360 KEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQEL 1419
Query: 575 AIMKAIREE---ELRKEKDGKSALVENGEGCEAEKQGL-EKTV--------LERRASNLD 718
+ +K +E+ +L DG + L E+ + +K+ L EK V L+ L
Sbjct: 1420 SKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELS 1479
Query: 719 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 898
+ +E L++ + +A+ E + + + E+ +E + + + ++
Sbjct: 1480 NNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQIN 1539
Query: 899 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDL 1078
EK+ L + C++L+ L E EIE++ E++ + +EL + +++ ND+
Sbjct: 1540 NEKEQLNQECNELKQNLKELQSKIE----EIEQEKESNEIKKKEELQELQEEITEKDNDI 1595
Query: 1079 DHVKAERQVLESKVSDMETTYSTLNN------ELQQKMDDNEAFL-NERDGLEAVKQGLE 1237
++K E + +E ++ + E ++N EL+ K+ + + L E+ E++ E
Sbjct: 1596 KNLKEEIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESISNEFE 1655
Query: 1238 KR----VLDLEATIHDI-EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD 1402
+ +++L+ +++ +M K +D NE E EL+E I +K K ++
Sbjct: 1656 ETKEQVLVELQRVNNEMNKMNEIKQEDENEKE---------ELQEHI----NKLKSQIER 1702
Query: 1403 INIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 1513
N L EV++L+ +L++ E + +++ ++ S L+
Sbjct: 1703 ENEQLKEVSKLKWELSELKTENESMKQMIMNKKSLLD 1739
Score = 92.8 bits (229), Expect = 6e-16
Identities = 118/544 (21%), Positives = 236/544 (43%), Gaps = 53/544 (9%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRN--------ILEAAKQALEYKVADLEAAKTTLND---ELER 196
+N+EL + K++KK I ++N I E +++E K ++ + T++ + LE
Sbjct: 982 INNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEE 1041
Query: 197 KKDDNNAIIKKALDKRISDL-----KADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
K + I +K D+ IS+L + + ++ E+ N + ++
Sbjct: 1042 SKGERIEI-EKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLN 1100
Query: 362 N-----------LEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
N + ++ L +L + + + KDL+ ++ +NE +E +
Sbjct: 1101 NQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERN 1160
Query: 509 SLKEHFLREEEDEVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGL 679
+ E + E+ LE++ L ++ + E L K KD ++L+ N + EK L
Sbjct: 1161 KINEEYKTVNEE--LEKNKKELNDLQTKYDNEILELNKNKDELNSLINN---LKEEKTNL 1215
Query: 680 EKTV--LERRASNLDT-----MDAIHE--EELRKEKVDKSALTENGEGCEAEKQGPEKTV 832
E+ V +E S L T D + + EEL + K +K + + EK K +
Sbjct: 1216 EEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEK----KRI 1271
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA---EIERKL 1003
+ + I + N ++ + +++ EK+ L K + N L + + EIE K
Sbjct: 1272 EEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKN 1331
Query: 1004 EASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 1183
+ +N E+ K K+++E++ +L+ +K E+ L + +S+ S LN E++ +
Sbjct: 1332 QEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEK 1391
Query: 1184 EAFLNE-----------RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL 1330
E E +D LE Q L K + E IHD+ T +D N+ L
Sbjct: 1392 EGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDL---TNGNDGINQ-----L 1443
Query: 1331 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKL 1510
+ +++++ LT+K +L +IN SE EL +L+ E + + + + V + +
Sbjct: 1444 NEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEER 1503
Query: 1511 EKCI 1522
++ +
Sbjct: 1504 DELV 1507
Score = 90.9 bits (224), Expect = 2e-15
Identities = 112/547 (20%), Positives = 245/547 (44%), Gaps = 57/547 (10%)
Frame = +2
Query: 47 TLNDELLNEKDDKKCIVN--DRNILEAAKQALEYK--VADLEAAKTTLNDELERKKDDNN 214
T+N+EL K + + D ILE K E + +L+ KT L +++++ +++ +
Sbjct: 1168 TVNEELEKNKKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKS 1227
Query: 215 AIIKKALDKR--ISDLKADAPQRDQEDDM--NALIXXXXXXXXXXXXXXXIVS-NLEVNI 379
+I + + +S L + Q QE + N L I++ N E+
Sbjct: 1228 KLITELSNGSDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIK- 1286
Query: 380 LILHEELQKEKDDKTALIKDLVAAEPGKRTV-NEI------VSHLESKSRSL-----KEH 523
EE +K +++K L+K++ + G + NEI + +E K++ + KE
Sbjct: 1287 ----EEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEI 1342
Query: 524 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 703
+EE E L++ + + K+ +L DG S L E E EK+G+ K + +
Sbjct: 1343 AKFKEEQENLQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLK 1402
Query: 704 ASNLDTMDAIHE--EELRKEKVDKSAL----TENGEGCEAEKQGPEKTVLDLEPTIPSLN 865
N D + + +EL K K +K L T +G + + D E + N
Sbjct: 1403 EENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEE-LTEKN 1461
Query: 866 DALQRDLDRVMAEKQALEKRCS----DLEAKNASLTDNQEGHEA-------------EIE 994
LQ +++++ +E + L S L+ N + +E + ++E
Sbjct: 1462 VQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVE 1521
Query: 995 RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKM 1174
+L + N+++ + ++KE + + + +K + L+SK+ ++E + + ++++
Sbjct: 1522 EELNFNGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEKESNEIKKKEEL 1581
Query: 1175 DDNEAFLNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE-----AEKQTLKK 1336
+ + + E+D ++ +K+ +E+ +L+ D+E + ++ E E Q L +
Sbjct: 1582 QELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLE 1641
Query: 1337 RISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESK-------EKQDLEKRVLE 1495
+ +E+IS ++ K+ + L E+ + ++NK ++ EK++L++ + +
Sbjct: 1642 EEKKEKESISNEFEETKEQV------LVELQRVNNEMNKMNEIKQEDENEKEELQEHINK 1695
Query: 1496 LTSKLEK 1516
L S++E+
Sbjct: 1696 LKSQIER 1702
Score = 79.7 bits (195), Expect = 5e-12
Identities = 112/543 (20%), Positives = 235/543 (43%), Gaps = 37/543 (6%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEY---KVADLEAAKTTLNDELERKKDDN 211
I+ LN+EL K +K+ I + LE K+ LE ++ +++ AK L +E + ++
Sbjct: 899 ISKLNEELTQTKQEKEEI---QKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEK 955
Query: 212 NAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS-NLEVNILIL 388
+ ++ + + + ++++E+ N L I++ N E+
Sbjct: 956 TNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIK---- 1011
Query: 389 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLER--- 559
EE K ++KT I L + + E+ LE E + +E D V+
Sbjct: 1012 -EENIKSIEEKTQEINSLTTS------IEELKGRLEESKGERIE--IEKERDRVISELND 1062
Query: 560 -SASNLAIMKAIREE-----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDT 721
N + K + E E++K +G + N + + ++ + + L T
Sbjct: 1063 IKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQT 1122
Query: 722 M---DAIHEEELRKEKVDK----SALTENGEGCEAEKQGPE---KTVLD-LEPTIPSLND 868
I+ EE++K+ ++ + + E + E E+ KTV + LE LND
Sbjct: 1123 QLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNKKELND 1182
Query: 869 ALQRDLDRVMAE----KQALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNLTH--- 1024
LQ D + E K L ++L+ + +L + + E E + + E SN +
Sbjct: 1183 -LQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVS 1241
Query: 1025 --NDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN 1198
N+EL + K +KE I N+L+ +K E++ +E + + + + E ++ ++ + L
Sbjct: 1242 KLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLK 1301
Query: 1199 ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 1378
E + + L+ + ++ + +IE K + N E K+ L++ ++ + +
Sbjct: 1302 EIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKE 1361
Query: 1379 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL---TSKLEKCICGARDGLST 1549
+ KL+ D++ +++L E++ +KEK+ + K + L +K++ + LS
Sbjct: 1362 EKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSK 1421
Query: 1550 IKE 1558
+KE
Sbjct: 1422 VKE 1424
Score = 72.0 bits (175), Expect = 1e-09
Identities = 76/381 (19%), Positives = 162/381 (42%), Gaps = 36/381 (9%)
Frame = +2
Query: 461 KRTVNEIVSHLESK---SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 631
KR E H S+ + SL EE + + EEL+K+ D +
Sbjct: 145 KRNSTENTGHSSSEHSATSSLASETTAEEVNRSVNAQIEEENKRLQNENEELKKKCDAQD 204
Query: 632 ALVENGEGCEAEK-------QGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 790
+L++ E E + +K ++++ A+ D M ++EE L + K +K ++
Sbjct: 205 SLLKTKMKSEMEAKKKVEILENEKKDLIDKMANENDGMSKLNEE-LTQIKNEKESINNEL 263
Query: 791 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN- 967
+ EK+ + L+ ND + +L++V EK + ++ + + +N + +
Sbjct: 264 IQTKQEKESINNELTQLKTD----NDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNEL 319
Query: 968 ----QEGHEAEIERKLEASNLTH-------------------NDELHKEKDDKESIMNDL 1078
QE E E E K + + N+EL + K +KE I N+L
Sbjct: 320 SQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNEL 379
Query: 1079 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 1258
+ +K E++ +E + + + + E ++ ++ + L E + + L+ + ++
Sbjct: 380 NSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQ 439
Query: 1259 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 1438
+ +IE K + N E K+ L++ ++ + ++ +K + N + T+ +
Sbjct: 440 TRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKE 499
Query: 1439 EDLNKESKEKQDL--EKRVLE 1495
+LNK +EK+ + EK +E
Sbjct: 500 NELNKLKEEKEQIFNEKTTIE 520
>ref|XP_001582797.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121917034|gb|EAY21811.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 1553
Score = 103 bits (257), Expect = 3e-19
Identities = 108/486 (22%), Positives = 216/486 (44%), Gaps = 23/486 (4%)
Frame = +2
Query: 128 QALEYKVADLEAAKTTLNDEL---ERKKDDNNAIIK------KALDKRISDLKADAPQRD 280
++L+ + A+L+A L D+L ++D N+IIK KAL DL A Q
Sbjct: 117 ESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDKDNQFKALQAERDDLAAKINQLT 176
Query: 281 QEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDL------ 442
Q+ +N S + N + +++ DDKT+ DL
Sbjct: 177 QKCQLNDAEKNALQAKLDSSENSLNESRNQCNFI------KQQLDDKTSQCNDLGTKLSQ 230
Query: 443 ---VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRK 613
AE + +N++ + +++KS+ +K++ EDE+ + + +MK +EE +
Sbjct: 231 ADQTIAEKIE-AINQLNNEIDNKSKIIKQY-----EDELAKSKEDSEELMKKYQEETDKL 284
Query: 614 EKDGKSALVE-NGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG 790
+KD ++ E + AE +K L+ L ++ E++++ + DKS L
Sbjct: 285 KKDSENLQNELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQIKVLQDDKSNLEIQR 344
Query: 791 EGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQ 970
E E E + +K+ + + + L + ++ E L+K+ DL + +N
Sbjct: 345 EKLEQEVEELKKSQQENDEKYQKEKEDLTQTVNNQNNEISNLKKQNEDLSNSTTNEINNL 404
Query: 971 EGHEAEIERK---LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTY 1141
+++ + LE N +N+ + D+ ++ ++ E+ L+ + ++ T
Sbjct: 405 NKQIQDLQNQKSDLEKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKETENLSNTV 464
Query: 1142 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEK 1321
+ NNE+++ NE NE+ L+ VK+ L + + I D++ K ++ + +
Sbjct: 465 NDKNNEIEELKKQNEDLQNEKQNLQKVKEDLTNTITTKDDEIKDLK----KQNEDLQNQN 520
Query: 1322 QTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ-EDLNKESKEKQDLEKRVLEL 1498
L+K+ +L ++ D LK+ N L E + Q +D+N K QDLE +V +L
Sbjct: 521 NDLEKQKEDLNNTVAN-KDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLEDKVTDL 579
Query: 1499 TSKLEK 1516
K+++
Sbjct: 580 EGKIDE 585
Score = 95.5 bits (236), Expect = 8e-17
Identities = 128/631 (20%), Positives = 246/631 (38%), Gaps = 129/631 (20%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q L+ D TI T +DE+ + K + + N N LE K+ L VA+ ++ L
Sbjct: 486 QNLQKVKEDLTNTITTKDDEIKDLKKQNEDLQNQNNDLEKQKEDLNNTVANKDSELNNLK 545
Query: 182 D------ELERKKDDNNAIIKKA---LDKRISDL--KADAPQRDQEDDMNALIXXXXXXX 328
+ E +K++D+ +KK+ L+ +++DL K D + E M +
Sbjct: 546 NDNQQLQEANKKQNDDINNLKKSNQDLEDKVTDLEGKIDEMTAENEGLMENVKTRDLQLD 605
Query: 329 XXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES--- 499
V L N L L ++ D L + E K + + V LE
Sbjct: 606 NLQGEHSQTVDELNQNNLSLQMQIDSLNSDVNDLKSQKDSLEKDKSDLEKKVKELEEALE 665
Query: 500 --KSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQ 673
K+ SL EE + L + L + + ++K ++ K+ L +N +
Sbjct: 666 DEKNSSLLNSSNFNEESQKLMDKINELTKQNREKNQNIKKLENEKANLQQNNDNLNQRLD 725
Query: 674 GLEKTVLERRASNLDTMDAIHE--EELRKEKVDKSALTENGEGCEA-------------- 805
++K + +AS + + ++ E+ KE+ + L++ + +
Sbjct: 726 NVKKQYEDLQASKSELVGKYNDLVEKFNKERQTNNELSQQNQAQKQQIQQLMNDLASLRD 785
Query: 806 ------------------EKQGPEKTVLDLEPTIPSLNDALQR----------------- 880
E+Q KT DL+ I L DAL +
Sbjct: 786 GKSDIVQKYNDLVAKFNDERQEAAKTKSDLQNQIQQLKDALAKAESNQKETQNKLDISNS 845
Query: 881 DLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLE---ASNLTHNDELHKEKD 1051
DL++ + ++LE+ + L++K + + + E+++E + + +SN +D+L K +
Sbjct: 846 DLEKEKDKSKSLEEELAALKSKLQQVQEEKANLESDLENERQNNSSSNAELSDKLSKLQQ 905
Query: 1052 DKESIMN---------------------DLDHVKAERQVLESKVSDMETTYSTLNNELQQ 1168
+ ++N DLD++ Q LES+++DM+ L+ +L
Sbjct: 906 ENRDLVNQINQLQNDLKQKESEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDELSKKLSN 965
Query: 1169 KMDDNEA--------------FLNERDGLEAVKQGLEKRVLDLE-------ATIHDIEMK 1285
+DDNE NE+D L E LDL I D++
Sbjct: 966 LVDDNERKDKLIDDLNSQLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLKVIEDLQRS 1025
Query: 1286 TGKDDDYNEA----------EKQTLKKRISELEEAISIL-------TDKAKKLLKDINIW 1414
++ D N + E LK+++++LE+ +S L ++ KL D+
Sbjct: 1026 LSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQVSNLKQENETQNEEISKLNNDLREA 1085
Query: 1415 LSEVTELQEDLNKESKEKQDLEKRVLELTSK 1507
+ ++++ K KE Q L++ + +L ++
Sbjct: 1086 ADYIEKIKQQYLKLKKENQALKEEISKLKAE 1116
Score = 89.0 bits (219), Expect = 8e-15
Identities = 120/559 (21%), Positives = 237/559 (42%), Gaps = 59/559 (10%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVAD-------LEAA 166
LE + AD+ T++ NDEL N K + + N+++ L+ + L V D L+
Sbjct: 418 LEKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKETENLSNTVNDKNNEIEELKKQ 477
Query: 167 KTTLNDELER----KKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXX 334
L +E + K+D N I K D I DLK D ++ N L
Sbjct: 478 NEDLQNEKQNLQKVKEDLTNTITTK--DDEIKDLKKQ--NEDLQNQNNDLEKQKEDLNNT 533
Query: 335 XXXXXXIVSNLEVNILILHEELQKEKDDKTAL------IKDLVAAEPGKRTVNEIVSHLE 496
++NL+ + L E +K+ DD L ++D V GK ++E+ + E
Sbjct: 534 VANKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLEDKVTDLEGK--IDEMTAENE 591
Query: 497 SKSRSLKEHFLR------EEEDEVLERSASNLAIMKAIRE--EELRKEKDGKSALVENGE 652
++K L+ E V E + +NL++ I ++ K K +L ++
Sbjct: 592 GLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVNDLKSQKDSLEKDKS 651
Query: 653 GCEAEKQGLEKTVLERRASNL-----------DTMDAIHE---------EELRKEKVDKS 772
E + + LE+ + + + S+L MD I+E + ++K + +K+
Sbjct: 652 DLEKKVKELEEALEDEKNSSLLNSSNFNEESQKLMDKINELTKQNREKNQNIKKLENEKA 711
Query: 773 ALTENGEGCEAEKQGPEKTVLDLEPTIPSL----NDALQR---------DLDRV-MAEKQ 910
L +N + +K DL+ + L ND +++ +L + A+KQ
Sbjct: 712 NLQQNNDNLNQRLDNVKKQYEDLQASKSELVGKYNDLVEKFNKERQTNNELSQQNQAQKQ 771
Query: 911 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVK 1090
+++ +DL ASL D + ++I +K NDE + K + N + +K
Sbjct: 772 QIQQLMNDL----ASLRDGK----SDIVQKYNDLVAKFNDERQEAAKTKSDLQNQIQQLK 823
Query: 1091 AERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIH 1270
ES + + N++L+++ D +++ E L++ Q +++ +LE+ +
Sbjct: 824 DALAKAESNQKETQNKLDISNSDLEKEKDKSKSLEEELAALKSKLQQVQEEKANLESDLE 883
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN 1450
+ + N + L ++S+L++ L ++ +L D+ SE+ ++ DL+
Sbjct: 884 N-------ERQNNSSSNAELSDKLSKLQQENRDLVNQINQLQNDLKQKESEIQKVSSDLD 936
Query: 1451 KESKEKQDLEKRVLELTSK 1507
+ QDLE ++ ++ K
Sbjct: 937 NLNNVIQDLESQMNDMQGK 955
Score = 78.6 bits (192), Expect = 1e-11
Identities = 122/554 (22%), Positives = 217/554 (39%), Gaps = 54/554 (9%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDD---------------KKCIVNDRNILEAAKQALEY 142
L N++ + I DEL K+D KK N +N L+ K E
Sbjct: 245 LNNEIDNKSKIIKQYEDELAKSKEDSEELMKKYQEETDKLKKDSENLQNELQNQKSLAEL 304
Query: 143 KVADLEAAKTTLNDELERKKDDNNAIIK--KALDKRISDLKADAPQRDQEDDMNALIXXX 316
+D K L +++ +DDN+ + K K L S+L+ + +QE
Sbjct: 305 NASD----KGNLQSAVKQLQDDNSNLEKQIKVLQDDKSNLEIQREKLEQE---------- 350
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLE 496
V L+ + E+ QKEK+D T + + N +S+L+
Sbjct: 351 -------------VEELKKSQQENDEKYQKEKEDLTQTVNNQ----------NNEISNLK 387
Query: 497 SKSRSLKEHFLRE-----EEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
++ L E ++ + L+ S+L A + D + L + + +
Sbjct: 388 KQNEDLSNSTTNEINNLNKQIQDLQNQKSDLEKQNADYNNTVSNNNDELANLKKLNQELQ 447
Query: 662 AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
EK L+K + D + I EEL+K+ D + EKQ +K DL
Sbjct: 448 NEKSNLQKETENLSNTVNDKNNEI--EELKKQNED----------LQNEKQNLQKVKEDL 495
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE------RKL 1003
TI + +D + +DL + + + L+ + +DLE + L + ++E+ ++L
Sbjct: 496 TNTITTKDDEI-KDLKK---QNEDLQNQNNDLEKQKEDLNNTVANKDSELNNLKNDNQQL 551
Query: 1004 EASNLTHNDELH---KEKDDKESIMNDL----DHVKAERQVLESKVSDMETTYSTLNNEL 1162
+ +N ND+++ K D E + DL D + AE + L V + L E
Sbjct: 552 QEANKKQNDDINNLKKSNQDLEDKVTDLEGKIDEMTAENEGLMENVKTRDLQLDNLQGEH 611
Query: 1163 QQKMDDN-----------EAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD---- 1297
Q +D+ ++ ++ + L++ K LEK DLE + ++E +
Sbjct: 612 SQTVDELNQNNLSLQMQIDSLNSDVNDLKSQKDSLEKDKSDLEKKVKELEEALEDEKNSS 671
Query: 1298 ----DDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKE 1465
++NE E Q L +I+EL + KKL + L + L+ K+
Sbjct: 672 LLNSSNFNE-ESQKLMDKINELTKQNREKNQNIKKLENEKANLQQNNDNLNQRLDNVKKQ 730
Query: 1466 KQDLEKRVLELTSK 1507
+DL+ EL K
Sbjct: 731 YEDLQASKSELVGK 744
Score = 71.6 bits (174), Expect = 1e-09
Identities = 116/549 (21%), Positives = 219/549 (39%), Gaps = 49/549 (8%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + D I L ++L ++ + + + +D + L Q LE ++ D++ L+ +
Sbjct: 903 LQQENRDLVNQINQLQNDLKQKESEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDELSKK 962
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDM--NALIXXXXXXXXXXXXXXXIVS 361
L DDN + DK I DL + + E D N L ++
Sbjct: 963 LSNLVDDN-----ERKDKLIDDLNSQLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLK 1017
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE------- 520
+E L L +EKD + + L + E V+ LE + +LK+
Sbjct: 1018 VIED----LQRSLSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQVSNLKQENETQNE 1073
Query: 521 ------HFLREEEDEVLERSASNLAIMK---AIREE--ELRKEKDGKSALVE--NGEGCE 661
+ LRE D + + L + K A++EE +L+ E D ++ ++ N + +
Sbjct: 1074 EISKLNNDLREAADYIEKIKQQYLKLKKENQALKEEISKLKAENDEHNSTIDQLNDDKRD 1133
Query: 662 AEKQ--GLEKTVLERRASNLDTMDAIHEEELRKEKVD-------KSALTENGEGCEAEKQ 814
E+Q L T+ E ++ + + EE K+ ++ KS + +N E EAE
Sbjct: 1134 LEEQLKELNITLDEEKSKSFSLNENASEELKNKDDINDGLKSQLKSQVQQNKE-IEAENH 1192
Query: 815 GPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEA--- 985
V + S ND L+ + E L+ S E KN + + + +
Sbjct: 1193 NLRSQVDQYK----SSNDELETQISNYQEENSNLQDLLSSSENKNKDINEQNKQLKQKLQ 1248
Query: 986 EIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQ 1165
++E L S +N+ + D+ + L + S+ ++ LNN L
Sbjct: 1249 QLENSLRESENKYNNLVKSNCDEITKLSQQLQDAMQDNAKYSSEKDNLIKKLKELNNNLN 1308
Query: 1166 QKMDDNEAFLNERDGLEAVKQGLEKRVLDL------EATIHDI--EMKT-GKDDDYNEAE 1318
+ N+ N+R LE Q L+ ++ +L I D+ +M+T ++++ +
Sbjct: 1309 VQKSQNKQIENQRSFLERENQRLKSQISELSKNQIPSVDIEDLKYQMRTLTIENEHLKKN 1368
Query: 1319 KQTLKKRISELEEA---ISILTDKAKKLLKDIN---IWLSEVTELQEDLNKESKEKQDLE 1480
+++R+ LE +SI ++ + L + +WLS + K KE DL
Sbjct: 1369 NDEIRQRMRHLESTNAQLSIQNNQNELKLCTLEQRCVWLSGAHD------KLRKENFDLS 1422
Query: 1481 KRVLELTSK 1507
+ + SK
Sbjct: 1423 STIDTMNSK 1431
>ref|XP_001312904.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121894768|gb|EAX99974.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 3748
Score = 103 bits (257), Expect = 3e-19
Identities = 112/518 (21%), Positives = 235/518 (45%), Gaps = 25/518 (4%)
Frame = +2
Query: 35 ATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNN 214
A + LN++L ++ D+ +V L++AK E K +L+A +++DE+ + KD+
Sbjct: 522 AELNKLNEQLKSKMDE---MVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELE 578
Query: 215 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVN--ILIL 388
I D + DLK D +N L+ I +N E+N I++L
Sbjct: 579 VIP----DFEVDDLK---------DQLNELLKEKEELEKEK-----IKNNDELNSSIIML 620
Query: 389 HEELQKEKDDKTALIKDLVAAEPGKRT--VNEIVSHLESKSRSLKEHFLREEEDEVLERS 562
+E+QKEK +K D ++ E KR +N+ S L+ + SL+ + E D++ E
Sbjct: 621 KDEIQKEKANK-----DKISEEKNKRDKELNDEKSKLQDELDSLQLDEIENENDQLFE-- 673
Query: 563 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE 742
E E K K + ++ N + + +++ +E++ +L+ + +
Sbjct: 674 -----------EVEDLKSKVDDAKILYNDMVDKIDDLKQQRSKVEQKYKDLEKQNKEKSD 722
Query: 743 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSL------NDALQRDLDRVMAE 904
E+ K + S L E + K + ++ + N+ +Q +++++ E
Sbjct: 723 EIEKVSKEISELKEKLDNLNQFKDNTPELHQKVDAMNEQIVKKSQENEKIQEEMNKLNEE 782
Query: 905 KQALEKRCSDLEAKN---ASLTDNQEGHEAEIERKLEASN---------LTHNDELHKEK 1048
Q LE ++E N ++ + + + +IE K +++ + ++ KE
Sbjct: 783 LQHLENEMEEIEVVNDERETIQEKIDNIKQQIEEKKKSNEEIQDIMNLLIEAENDAQKEL 842
Query: 1049 DDKESIMNDLDHVKAERQVLESKVSDMETTYSTL---NNELQQKMDDNEAFLNERDGLEA 1219
DD E + + ++ Q L+ + D + + L NN+LQ+++ D + L++ + +
Sbjct: 843 DDIEIVEAQSEEIRQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDLQNELDQTELVND 902
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 1399
+ L K++ +++ I++ + + + + NE + ++K EL+E I I+ DK+ KL
Sbjct: 903 DSESLNKKLDEIKEQINERKSQNENNTEQNEKLIEEIEKFAKELDE-IEIIEDKSDKLQA 961
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLE 1513
I+ ++ E Q++ + K DLE + KL+
Sbjct: 962 QISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLD 999
Score = 90.1 bits (222), Expect = 4e-15
Identities = 117/543 (21%), Positives = 243/543 (44%), Gaps = 25/543 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTT-- 175
+ +E+K +A I+ L ++ ++ + + N LE Q + K+ + + K
Sbjct: 950 EIIEDKSDKLQAQISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKNNSD 1009
Query: 176 --------LNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 331
+N E+E+ +D NN + ++ DK +L+ D +++ I
Sbjct: 1010 YLKSEIENVNKEIEKIRDTNNKLKQELQDKN-KELEEMTDIADNSEELKEKIDSVNEEIT 1068
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
+ +N ++ LI H L +DL AE +++ + + +S +S
Sbjct: 1069 KR-----VANNTTIDELIRH------------LHEDLKNAEAKLQSIPHVDDNTDSLQKS 1111
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQGLEKT 688
L E L + + E N I + I+E EE E + + + E +E + ++
Sbjct: 1112 LDE-VLAQISQKQRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEIETVKSQ 1170
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLND 868
+ E++ +N + I EE +K + L + E Q E ++E T +++
Sbjct: 1171 IEEKKKNN----EKIAEEN-KKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISE 1225
Query: 869 ALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN--LTHNDELHK 1042
Q++LD + KQ LE+ + ++K +++ E + +I+ K + + +N+E
Sbjct: 1226 K-QKELDEL---KQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEEKQS 1281
Query: 1043 EKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER------ 1204
E D+K + DL+ +K E + + ++ E T + + QQK ++N+ LNE
Sbjct: 1282 ELDEKLKELQDLEEIKDETEEINQQI---EETQKEIETKKQQKENNNK--LNEELDKLKQ 1336
Query: 1205 --DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE---EAISI 1369
+ +E V+ +EK ++E DI+ K ++D EA + +++ ++ L+ E I
Sbjct: 1337 DLEQIENVEDNVEKLTEEIEKVKSDIDSKHQLNNDIKEA-NEVVEEELNSLKEELEKIEP 1395
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD-LEKRVLELTSKLEKCICGARDGLS 1546
+ DK+ ++ K+I + + + E ++ N E + L K + +L ++LE+ I +D
Sbjct: 1396 VEDKSDEIRKEI-VKIQKEIETKKATNCGISESNELLNKELNDLKNQLEE-IAEEKDDSE 1453
Query: 1547 TIK 1555
IK
Sbjct: 1454 EIK 1456
Score = 87.0 bits (214), Expect = 3e-14
Identities = 117/521 (22%), Positives = 225/521 (43%), Gaps = 33/521 (6%)
Frame = +2
Query: 53 NDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 232
N++L E D K + D N + Q L+ ++++L+ E ++K + + + +
Sbjct: 2652 NEKLKEEIDALKEELKD-NKSQEENQQLKSQISELQ--------EQIKQKQNEISETENS 2702
Query: 233 LDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQK 406
L +IS L+ + +++ E D N+L + L ++L+K
Sbjct: 2703 LKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQEIENKADSSQLSDLLKDLKK 2762
Query: 407 ---EKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK---EHFLREEEDEVLERSAS 568
E ++ IK ++ E K ++ LE + +SL E+ +E+ E+LE S
Sbjct: 2763 KLQELTEENETIKSKISEE--KEKSKSEMAKLEEEKKSLNKELENVNDDEDKEMLEGEVS 2820
Query: 569 NLA----IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIH 736
+L + K I EE+ +K K L E + + L+K + +++
Sbjct: 2821 SLKETLNLKKQINEEQKQKLSQEKEKLTEELSQLN-DNEDLKKEIEQKK----------- 2868
Query: 737 EEELRKEKVDKSALTENGE-----GCEAEKQGPE--KTVLDLEPTIPSLNDALQRDLDRV 895
EEL K K D S L E + ++EKQ PE K + DL+ I + + D +
Sbjct: 2869 -EELEKLKNDSSLLQELQDLKKQIEEKSEKQNPELLKQIEDLKKEISEK----ESENDLI 2923
Query: 896 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEI-ERKLEASNLTHNDELHKEKDDKE--SI 1066
EK +E++ + L + L E + ++ + + + L+ + + ++KE I
Sbjct: 2924 TGEKNTVEQQYNKLVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNNQFRIDNEKEFQEI 2983
Query: 1067 MNDLDHVKAERQVLESKVSDMETT---YSTLNNE----LQQKMD----DNEAFLNERDGL 1213
++ +K +R+ L K ++ + Y+TL + QQK+D NE L
Sbjct: 2984 KKSIEEIKGQREQLAKKHNEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQ 3043
Query: 1214 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 1393
E LEK DLE ++E + D+++ + + L+K+ EL++ L+ K K+
Sbjct: 3044 EKTVSNLEKESEDLEQKNKELEQQMTSTGDFSQDKIEELRKKKEELQKLNDELSQKQKQN 3103
Query: 1394 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++ N +E L ++ + +EK E+ KLE+
Sbjct: 3104 IEQSNSLQNEKVTLSNEIESLKSSTEAMEKESTEMEKKLEE 3144
Score = 82.4 bits (202), Expect = 7e-13
Identities = 116/523 (22%), Positives = 219/523 (41%), Gaps = 21/523 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLND------ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEA 163
Q +ENK AD L D EL E + K +++ K+ + ++A LE
Sbjct: 2742 QEIENK-ADSSQLSDLLKDLKKKLQELTEENETIKSKISEE------KEKSKSEMAKLEE 2794
Query: 164 AKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQ-EDDMNALIXXXXXXXXXXX 340
K +LN ELE DD + K+ L+ +S LK + Q ++ +
Sbjct: 2795 EKKSLNKELENVNDDED---KEMLEGEVSSLKETLNLKKQINEEQKQKLSQEKEKLTEEL 2851
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 520
+L+ I EEL+K K+D + L + + ++ +E KS
Sbjct: 2852 SQLNDNEDLKKEIEQKKEELEKLKNDSSLL-----------QELQDLKKQIEEKSEKQNP 2900
Query: 521 HFLREEED---EVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV 691
L++ ED E+ E+ + N I E + K LVE + E+ + +K V
Sbjct: 2901 ELLKQIEDLKKEISEKESENDLITGEKNTVEQQYNK-----LVEQRKYLESTMEAAKKKV 2955
Query: 692 LERRAS----NLDTMDAIHEEELRKEKVDKSALTENGEGCE-AEKQGPEKTVLDLEPTIP 856
+ R ++ + E +++ KS G+ + A+K +K T+
Sbjct: 2956 SDLRQQCDELSMKNNQFRIDNEKEFQEIKKSIEEIKGQREQLAKKHNEDKRRAREYNTLA 3015
Query: 857 --SLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHND 1030
L DA Q+ LD A+ + L K S+ E ++L E LE N
Sbjct: 3016 RQKLTDAQQK-LDAEKAKNENLLKMMSEQEKTVSNLEKESED--------LEQKNKELEQ 3066
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 1210
++ D + + +L K E Q L ++S + +N LQ ++ NE +
Sbjct: 3067 QMTSTGDFSQDKIEELRKKKEELQKLNDELSQKQKQNIEQSNSLQ---NEKVTLSNEIES 3123
Query: 1211 LEAVKQGLEKRVLDLEATIHD----IEMKTGKDDDYNEAEKQTLKKRISELEEAISILTD 1378
L++ + +EK ++E + + I K+ + +D + K+ +K +L++ ++ L +
Sbjct: 3124 LKSSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDLEKKSKEQQEKS-DKLKQEVAELQE 3182
Query: 1379 KAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSK 1507
KAKK+ + ++T+L+ ++ + K+DLE+ + + ++K
Sbjct: 3183 KAKKITTENTDLNDKITDLEISISNAERRKKDLEEEIEKSSAK 3225
Score = 81.3 bits (199), Expect = 2e-12
Identities = 134/586 (22%), Positives = 242/586 (41%), Gaps = 83/586 (14%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAA--KQALEYKVADLEAAKTT 175
QA E K + E A L + + + + N+ L+ Q +EYK + K
Sbjct: 2191 QATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEMEYKNYNESLTKIL 2250
Query: 176 --LNDELERKKDDNNAIIKKALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXX 346
L +LE +++N ++A + + +LKA A +R Q D N +
Sbjct: 2251 DKLKVKLEEVEEENRNEDERA--EEVENLKAQIASKRKQNDAENEKLSQEINKLKEE--- 2305
Query: 347 XXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHF 526
+ NL+ N I EE+++ +D I E K + + + L K+ L E
Sbjct: 2306 ---LQNLQENTEI--EEMKQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEKLAE-- 2358
Query: 527 LREEEDEVLERSASNLAIMKAIREE--ELRKEKDG-KSALVENGEGCEAEKQGLEKT--- 688
++E++ L NL +K+ E +L +E+DG + LVE + E + L+ T
Sbjct: 2359 -ADDENDKLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVEELNKLKEEYEQLQNTDDI 2417
Query: 689 -------------VLERRASNLDTM---DAIHE--------EELRKEKVDKSALTENGEG 796
+ E +ASN D D + E E + +E+ DK + + E
Sbjct: 2418 NDLKQEVIDLSKQIDEIKASNKDAQTKSDLLKELSQLNSQIENIIQEEEDKEEIRSHIEE 2477
Query: 797 CEA-----EKQGPEKTVLDLEPTIP---SLNDALQRDLDRVMAEKQALEKRCSDLEAKNA 952
++ + + EK + DL+ + SL + L+ D+ E + +K DLE +
Sbjct: 2478 IKSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLKEDIKLTKEENEKAQKNIDDLEQEFD 2537
Query: 953 SLTDNQEGH----------EAEIER------KLEASNLTHNDELHKEKDDKESIMNDLDH 1084
L + E E EIER + + N D+L KE +D +N L+
Sbjct: 2538 DLNNEYEEESQFDEERKLLETEIERLKQLISEKKTQNKEKTDKLFKEINDLTEELNSLED 2597
Query: 1085 VKAERQVLESKVSDMETTYST--------------------LNNELQQKMDDNEAFLNER 1204
+E + L+S++ ++ ++ LNN+LQQ ++D E +
Sbjct: 2598 -DSENKELQSQIDELNEQINSVKEESNPQQTKENLQKELDDLNNKLQQMIEDEEENEKLK 2656
Query: 1205 DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKA 1384
+ ++A+K+ L+ D+ ++ E Q LK +ISEL+E I K
Sbjct: 2657 EEIDALKEELK--------------------DNKSQEENQQLKSQISELQEQIK---QKQ 2693
Query: 1385 KKLLKDINIWLSEVTELQEDLNKESKEKQD----LEKRVLELTSKL 1510
++ + N S++++LQ +L ++ E+ D L K + L K+
Sbjct: 2694 NEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKI 2739
Score = 79.3 bits (194), Expect = 6e-12
Identities = 132/580 (22%), Positives = 246/580 (42%), Gaps = 30/580 (5%)
Frame = +2
Query: 56 DELLNEKDDKKCIVNDRNIL--EAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKK 229
DE+ E ++ K ++++N E AK E K ++L+ L D LE KD+ I +
Sbjct: 1249 DEISEEIENIKTQIDEKNKKNEEIAKNN-EEKQSELDEKLKELQD-LEEIKDETEEI-NQ 1305
Query: 230 ALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKE 409
+++ +++ Q++ + +N + + N+E N+ L EE++K
Sbjct: 1306 QIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQ-------IENVEDNVEKLTEEIEKV 1358
Query: 410 KDD---KTALIKDLVAA-EPGKRTVNEIVSHLES------KSRSLKEHFLREEEDEVLER 559
K D K L D+ A E + +N + LE KS +++ ++ ++ E+ +
Sbjct: 1359 KSDIDSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQK-EIETK 1417
Query: 560 SASNLAIMKAIREEELRKE-KDGKSALVE------NGEGCEAEKQGLEKTVLERRASNLD 718
A+N I ++ E L KE D K+ L E + E +AE + L K++ E++ N +
Sbjct: 1418 KATNCGISES--NELLNKELNDLKNQLEEIAEEKDDSEEIKAEIENLHKSIEEKKEHNAN 1475
Query: 719 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 898
T E KE++ K L E + E + E+
Sbjct: 1476 TQQ---NNENMKEELSK--LQEEFDQIEVVEDKAEEI----------------------- 1507
Query: 899 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHN-DELHKEKDDKESIMND 1075
+EK S +E KN + D +E ++ E E +NL DE+ E+D E +
Sbjct: 1508 --HSEIEKLKSQIEEKNTTNNDIKEANDILNE---ELNNLQKQYDEIDVEEDKSEELSQK 1562
Query: 1076 LDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE---KRV 1246
+ ++ ++LE K S ET S N L++ ++ NE D +E V E K++
Sbjct: 1563 VTDLQ---KLLEEKKSQNETIKSGNENILKEL----QSLQNELDNIEVVSSSSEEGEKKI 1615
Query: 1247 LDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV 1426
L+ I D + + + +NE +K +EL E I + DK+ L + I ++
Sbjct: 1616 EKLKQMISDKQKQNEETTKHNEELDNQIKDLENELNEIIPV-KDKSNDLQQQIEEIKDKI 1674
Query: 1427 TELQE------DLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPD 1588
T+ Q+ LN KE+ D K + + +E + + IK +
Sbjct: 1675 TDKQKKNEECSQLNTALKEEYDQLKSEFDNIAVIESKAEEIQQKIDEIKSE------IDQ 1728
Query: 1589 NWVPFEDLVQGFS-RKTSPLDITKTCDAVDISEDSTTNIQ 1705
++D+ +G + + + K + +++ ED T ++Q
Sbjct: 1729 KRKEYQDIKEGNDLLEEAYTEKQKELEQIEVVEDKTEDLQ 1768
Score = 76.3 bits (186), Expect = 5e-11
Identities = 114/528 (21%), Positives = 220/528 (41%), Gaps = 26/528 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
+EN+ E +LN+ + + ++ + RN ++ L+ ++A +E+ KT + DE
Sbjct: 268 IENEEGKTENLNYSLNEMIDLVAERRRALQELRNSQGKDEEKLKKQIAKVESEKTKIEDE 327
Query: 188 LERKKDDNNAIIKKALDK--------RISDLKADAPQRDQEDDMNALIXXXXXXXXXXXX 343
++ ++D IKK D+ +I++ K ++ ED L
Sbjct: 328 IKHLQEDEEPQIKKLKDRLDETTTKTQIAEKKLGEMRKTIEDSRQKLAQRRQNLIERRKE 387
Query: 344 XXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
N + ++ ++Q E D + + L VN++ S K +L+E
Sbjct: 388 LTNDAENTNTELQSINNQIQ-EIDSEFNKLNGL---------VNKVQSDHSKKKSALQEQ 437
Query: 524 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLE-- 697
++++D L A KA RE E+ K D L+KT+ E
Sbjct: 438 LAQKQKD--LNDLKRKQAEEKASREAEIAKIND-----------------QLQKTMKEYN 478
Query: 698 --RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
+ N+D + I ++ + K +S + + E + + V +L LN+
Sbjct: 479 DLNQPQNVDLKNEI-DQATKDLKELESRVNKKREELFGKN---NQRVAELN----KLNEQ 530
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKD 1051
L+ +D ++ Q L+ + EAK L +AEIE + +DE+ K KD
Sbjct: 531 LKSKMDEMVKADQELQSAKDEHEAKKNEL-------KAEIE--------SVSDEISKLKD 575
Query: 1052 DKESIMN-DLDHVKAERQVLESKVSDMETTYSTLNNELQQKM----DDNEAFLNERDGLE 1216
+ E I + ++D +K + L + ++E N+EL + D+ + +D +
Sbjct: 576 ELEVIPDFEVDDLKDQLNELLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKIS 635
Query: 1217 AVKQGLEKRVLDLEATIHDIEMKTGKDDDYNE-----AEKQTLKKRISELEEAISILTDK 1381
K +K + D ++ + D D+ NE E + LK ++ + + + + DK
Sbjct: 636 EEKNKRDKELNDEKSKLQDELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDK 695
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKESKEKQD----LEKRVLELTSKLE 1513
+ D+ S+V + +DL K++KEK D + K + EL KL+
Sbjct: 696 ----IDDLKQQRSKVEQKYKDLEKQNKEKSDEIEKVSKEISELKEKLD 739
Score = 74.3 bits (181), Expect = 2e-10
Identities = 87/378 (23%), Positives = 176/378 (46%), Gaps = 15/378 (3%)
Frame = +2
Query: 467 TVNEIVSHLESKSRSLKEHFLRE---EEDEVLERSASNLAIMKAIREEELRKEKDGKSA- 634
++NE++ + + R+L+E LR +++E L++ + + K E+E++ ++ +
Sbjct: 281 SLNEMIDLVAERRRALQE--LRNSQGKDEEKLKKQIAKVESEKTKIEDEIKHLQEDEEPQ 338
Query: 635 ---LVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK-SALTENGEGCE 802
L + + + Q EK + E R + D+ + + R+ +++ LT + E
Sbjct: 339 IKKLKDRLDETTTKTQIAEKKLGEMRKTIEDSRQKLAQR--RQNLIERRKELTNDAENTN 396
Query: 803 AEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALE-------KRCSDLEAKNASLT 961
E Q + +++ LN + + +K AL+ K +DL+ K A
Sbjct: 397 TELQSINNQIQEIDSEFNKLNGLVNKVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEK 456
Query: 962 DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTY 1141
++E A+I +L+ + +ND + D + N++D + + LES+V+
Sbjct: 457 ASREAEIAKINDQLQKTMKEYNDLNQPQNVD---LKNEIDQATKDLKELESRVNKKR--- 510
Query: 1142 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEK 1321
EL K + A LN+ + E +K +++ V D E+++ KD+ +EA+K
Sbjct: 511 ----EELFGKNNQRVAELNKLN--EQLKSKMDEMVKA------DQELQSAKDE--HEAKK 556
Query: 1322 QTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
LK I + + IS L D+ + ++ D EV +L++ LN+ KEK++LEK ++
Sbjct: 557 NELKAEIESVSDEISKLKDELE-VIPDF-----EVDDLKDQLNELLKEKEELEKEKIKNN 610
Query: 1502 SKLEKCICGARDGLSTIK 1555
+L I +D + K
Sbjct: 611 DELNSSIIMLKDEIQKEK 628
Score = 72.0 bits (175), Expect = 1e-09
Identities = 95/549 (17%), Positives = 232/549 (42%), Gaps = 59/549 (10%)
Frame = +2
Query: 2 QALENKVADFEAT---IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 172
+ +++K+ D + + LN L E D K ++ ++E+ + ++ K+ ++++
Sbjct: 1668 EEIKDKITDKQKKNEECSQLNTALKEEYDQLKSEFDNIAVIESKAEEIQQKIDEIKSEID 1727
Query: 173 TLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXX 352
E + K+ N+ ++++A ++ +L+ D+ +D+ LI
Sbjct: 1728 QKRKEYQDIKEGND-LLEEAYTEKQKELEQIEVVEDKTEDLQNLIDEITEQINSRKS--- 1783
Query: 353 IVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR 532
+NLE + +E +K+ + DL + ++ E + + K +K+ + R
Sbjct: 1784 --NNLERQVS--NETFEKQLGQLKQELNDLPQTDDNSESLKEEIEETKKKLAMMKDEYQR 1839
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
+++ +S ++ + IR E + + + ++EN +AEK+ + +
Sbjct: 1840 MSDED---KSLTD----ELIRVESELNDLENQKNVLENETIVKAEKKMQNDNTIMDLRNK 1892
Query: 713 LDTMDA-IHEEELRKEKVDK-------------SALTENGEGCEAEKQGPEKTVLDLEPT 850
+DT+ A + ++E +E ++K + +++N E E E + L+
Sbjct: 1893 IDTLKAQLQQQEKPQEDIEKLKKEYQELKFQFDAKVSQNKE----EVSHSENELHSLKEM 1948
Query: 851 IPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQE---GHEAEIERKLE-ASNL 1018
+ Q+ +D + ++ +++ + D KN + E +++ + +LE A N
Sbjct: 1949 YDKIEKVEQQQVDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSDAQNELEKAENK 2008
Query: 1019 THNDELHKEKDDKESIMNDLDHVKAERQVLESKV-------------------SDMETTY 1141
DEL + ++ E + + D K + + + S + SD+
Sbjct: 2009 VDPDELVRLSEEIEELKLEADEKKKQNEEVRSSLEEELSKYKEILENLKSDNQSDIHNQI 2068
Query: 1142 STLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEK 1321
+ + + +K +NEA + L+ + +K + ++ +I+ + ++ D N E
Sbjct: 2069 DQIKDRINEKQQENEA---DNQKLQEIINNHKKLLENMNKEHEEIQKQIEQEVDKNNKEI 2125
Query: 1322 QTLKKRISELEEAISILTDKAKKLLKDINIWL-------------------SEVTELQED 1444
+K I+E++E + +AKK +D + L SE+ L+++
Sbjct: 2126 DQKQKEINEVKEKLQ----QAKKENEDDKVELQRQIDNCGREIEKLQNAGDSEIDLLKQE 2181
Query: 1445 LNKESKEKQ 1471
++K+ KE+Q
Sbjct: 2182 IDKKEKERQ 2190
Score = 70.5 bits (171), Expect = 3e-09
Identities = 112/551 (20%), Positives = 231/551 (41%), Gaps = 52/551 (9%)
Frame = +2
Query: 11 ENKVADFEATIATLNDEL--LNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKT 172
++++A E +LN EL +N+ +DK+ + + + L KQ E + L K
Sbjct: 2786 KSEMAKLEEEKKSLNKELENVNDDEDKEMLEGEVSSLKETLNLKKQINEEQKQKLSQEKE 2845
Query: 173 TLNDELERKKDDNNAIIKKALDKR---ISDLKADAPQRDQEDDMNALIXXXXXXXXXXXX 343
L +EL + D+ + +KK ++++ + LK D+ + D+ I
Sbjct: 2846 KLTEELSQLNDNED--LKKEIEQKKEELEKLKNDSSLLQELQDLKKQIEEKS-------- 2895
Query: 344 XXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPG--KRTVNEIVS---HLESKSR 508
+L E+L+KE +K + DL+ E ++ N++V +LES
Sbjct: 2896 -----EKQNPELLKQIEDLKKEISEKESE-NDLITGEKNTVEQQYNKLVEQRKYLESTME 2949
Query: 509 SLKEHF--LREEEDEV--------LERSASNLAIMKAIREEELRKEKDGKSALVENGEGC 658
+ K+ LR++ DE+ ++ I K+I E + ++E+ K +
Sbjct: 2950 AAKKKVSDLRQQCDELSMKNNQFRIDNEKEFQEIKKSIEEIKGQREQLAK-------KHN 3002
Query: 659 EAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDK--SALTENGEGCEAEKQGPEKTV 832
E +++ E L R+ D + E+ + E + K S + E E + E+
Sbjct: 3003 EDKRRAREYNTLARQKLT-DAQQKLDAEKAKNENLLKMMSEQEKTVSNLEKESEDLEQKN 3061
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK---NASLTDNQEGHEAEIERKL 1003
+LE + S D Q ++ + +K+ L+K +L K N +++ + + + ++
Sbjct: 3062 KELEQQMTSTGDFSQDKIEELRKKKEELQKLNDELSQKQKQNIEQSNSLQNEKVTLSNEI 3121
Query: 1004 EASNLTHNDELHKEKDDKESIMND----LDHVKAERQVLESKVSDMETTYSTLNNELQQK 1171
E+ + + + KE + E + + + E++ LE K + + L E+ +
Sbjct: 3122 ESLK-SSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDLEKKSKEQQEKSDKLKQEVAEL 3180
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 1351
+ + E L ++ DLE +I + E + K D E EK + K + E
Sbjct: 3181 QEKAKKITTE-------NTDLNDKITDLEISISNAERR--KKDLEEEIEKSSAKS-LQEK 3230
Query: 1352 EEAISILTDKAKKLLKD---------------INIWLSEVTELQEDLNKESKEKQD---- 1474
E+ + + +K KK +++ I++ ++ L+E N K +Q+
Sbjct: 3231 EKELEEIAEKKKKEVREMKKQHKQNIRSLESSISLLEQDIKSLEEIQNSSKKSEQEGLQL 3290
Query: 1475 LEKRVLELTSK 1507
L+++V +L K
Sbjct: 3291 LDEKVADLKIK 3301
>ref|XP_001319569.1| viral A-type inclusion protein [Trichomonas vaginalis G3]
gi|121902355|gb|EAY07346.1| viral A-type inclusion
protein, putative [Trichomonas vaginalis G3]
Length = 940
Score = 101 bits (252), Expect = 1e-18
Identities = 129/561 (22%), Positives = 257/561 (45%), Gaps = 56/561 (9%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ L+ KV+D + I ++E+++ K + N L K LE ++ +L L+
Sbjct: 162 EKLKQKVSDEKDLIQVKDEEIIDLKQKNTDLSEQNNKLNEDKNELEKQIEELAQK---LS 218
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
DE E++K L + I++LK++ + + E D N + V+
Sbjct: 219 DESEKEK----------LKQEINELKSE--KENSEKDFNKKLENLTQK----------VT 256
Query: 362 NLEVNILILHEELQKEKDDKT--ALIKDLVAAEPGKRTVN--EIVSHLESK----SRSLK 517
LE +I E+ + + K +L D +A E K + N EI L K + K
Sbjct: 257 ELEDSISQKTREIDEAETAKEDISLKLDNLAEENEKLSQNLSEIYEKLNEKVTETEKLQK 316
Query: 518 EHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV-- 691
E+ + E+E+L++ S+ A + ++E E K+++G+ + E E + E +KTV
Sbjct: 317 ENEDLKSENELLKKD-SDSAQEELMKENENLKKENGE--ITEKIEELQKEIGERQKTVED 373
Query: 692 LERRASNLDTMDAIHEEELRKEKVDKSALTEN-----------GEGCEAEKQGPEKTVLD 838
L+++ +++ +A E+ +KE D + E + + EK+ +K V +
Sbjct: 374 LKQKIEEINSQNAEESEKNQKEIDDLTQEIEEINQKLDEKQKENDDLKKEKENLQKEVDE 433
Query: 839 LEPT----------IPSLNDALQRDLDRVMAEKQA-----------LEKRCSDLEAKNAS 955
++ + ND L++ +++ EKQ +K DL +N
Sbjct: 434 IKKNFEENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEE 493
Query: 956 LT---DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD--------HVKAERQ 1102
+ D ++ EI++K+E N N +L KE +D + L+ +V +E++
Sbjct: 494 MNQKLDEKQKEIEEIKQKIE-ENQKQNVDLKKEVEDLTQEIEKLEEQKSQKEENVNSEQE 552
Query: 1103 VLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM 1282
L+ ++ +++ T++NEL+ K NE ++ E K+ E + +E + E+
Sbjct: 553 NLQKQIEELKNEKETISNELESKTKHNEKLVSSLQ--EFAKKNAELDIT-IERLTQEKEV 609
Query: 1283 KTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNK 1453
+D +AE + LK ++ E +E I L ++ ++++K+ N + E Q++ +
Sbjct: 610 LINNVNDLQNNVDAEIRDLKVKLQEKDEEIDGLNEQIEQIIKENNDLKQKQEENQKENEQ 669
Query: 1454 ESKEKQDLEKRVLELTSKLEK 1516
+ KE +DL+K V +LT ++EK
Sbjct: 670 KQKENEDLKKEVDDLTQEIEK 690
Score = 98.2 bits (243), Expect = 1e-17
Identities = 114/560 (20%), Positives = 246/560 (43%), Gaps = 57/560 (10%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVND--RNILEAAKQALEYKVADLEAAKTTLN 181
++ ++ + + I L +EL + ++K+ +N+ I + KQ E K N
Sbjct: 4 IKKQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDLQKQIDEIK---------NQN 54
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+ L+++K+++ ++K+I DL Q+++E+ ALI +
Sbjct: 55 ENLQKEKENS----LNEMNKQIDDL-----QKEKEETEKALIEENEDYKNQLSELKKQIE 105
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE-- 535
+L+ E L+KE ++ IKDL + E++ S+S + F+ E
Sbjct: 106 DLQNENEEKVENLKKENEEFNNEIKDL-------QDQIELLKKSMSESEDKDQKFVIELN 158
Query: 536 EEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
++ E L++ S+ + +++EE+ K + L E +K LEK + E A L
Sbjct: 159 QQIEKLKQKVSDEKDLIQVKDEEIIDLKQKNTDLSEQNNKLNEDKNELEKQI-EELAQKL 217
Query: 716 DTMDAIHEEELRKEKVDKSALTENGEGCEAEK-QGPEKTVLDLEPTIPSL---------- 862
D +E+L++E + + EN E +K + + V +LE +I
Sbjct: 218 S--DESEKEKLKQEINELKSEKENSEKDFNKKLENLTQKVTELEDSISQKTREIDEAETA 275
Query: 863 --------------NDALQRDLDRV-------MAEKQALEKRCSDLEAKNASLTDNQEGH 979
N+ L ++L + + E + L+K DL+++N L + +
Sbjct: 276 KEDISLKLDNLAEENEKLSQNLSEIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSA 335
Query: 980 EAEIER-----KLEASNLTHN-DELHKEKDDKESIMNDL--------DHVKAERQVLESK 1117
+ E+ + K E +T +EL KE +++ + DL E + + +
Sbjct: 336 QEELMKENENLKKENGEITEKIEELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKE 395
Query: 1118 VSDMETTYSTLNNELQQKMDDNEAFLNERDGL----EAVKQGLEK---RVLDLEATIHDI 1276
+ D+ +N +L +K +N+ E++ L + +K+ E+ ++ +L+ D+
Sbjct: 396 IDDLTQEIEEINQKLDEKQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDL 455
Query: 1277 EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKE 1456
+ + + + E + +KK E ++ I LT + +++ + ++ E+ E+++ + +
Sbjct: 456 KKGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEEN 515
Query: 1457 SKEKQDLEKRVLELTSKLEK 1516
K+ DL+K V +LT ++EK
Sbjct: 516 QKQNVDLKKEVEDLTQEIEK 535
Score = 77.4 bits (189), Expect = 2e-11
Identities = 114/567 (20%), Positives = 239/567 (42%), Gaps = 68/567 (11%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
EN DF + L ++ +D + + E AK+ + K+ +L L+ L
Sbjct: 238 ENSEKDFNKKLENLTQKVTELEDSISQKTREIDEAETAKEDISLKLDNLAEENEKLSQNL 297
Query: 191 ERKKDDNNAIIKKA--LDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXXIV 358
+ N + + L K DLK++ ++D + L+
Sbjct: 298 SEIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSAQEELMKENENLKK--------- 348
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVA------------AEPGKRTVNEIVSHLESK 502
N E+ I EELQKE ++ ++DL +E ++ ++++ +E
Sbjct: 349 ENGEITEKI--EELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEIEEI 406
Query: 503 SRSLKEHFLREEEDEVLERSASNLA-----IMKAIRE-----EELRKEKDG-KSALVENG 649
++ L E +++E++ L++ NL I K E E L+KE D K + ++
Sbjct: 407 NQKLDE---KQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSS 463
Query: 650 EGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA-EKQGPE- 823
E + E + ++K E + +D + +EE +K + + E + E +KQ +
Sbjct: 464 EEKQKEIEEIKKN-FEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDL 522
Query: 824 -KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK 1000
K V DL I L + + + V +E++ L+K+ +L+ + ++++ E E+
Sbjct: 523 KKEVEDLTQEIEKLEEQKSQKEENVNSEQENLQKQIEELKNEKETISNELESKTKHNEKL 582
Query: 1001 LEA------SNLTHNDELHKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTL 1150
+ + N + + + +KE ++N+++ +V AE + L+ K+ + + L
Sbjct: 583 VSSLQEFAKKNAELDITIERLTQEKEVLINNVNDLQNNVDAEIRDLKVKLQEKDEEIDGL 642
Query: 1151 NNELQQ---------------------KMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 1267
N +++Q K +NE E D L + LE
Sbjct: 643 NEQIEQIIKENNDLKQKQEENQKENEQKQKENEDLKKEVDDLTQEIEKLE---------- 692
Query: 1268 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKD-------INIWLSEV 1426
E K+ K+++ +E++ L+K+I EL++ + + + L+++ + I ++
Sbjct: 693 ---EQKSQKEEENVNSEQENLQKQIEELKKEVEQYKKQNEDLIEENEEMDEKMKILQKQI 749
Query: 1427 TELQEDLNKESKEKQDLEKRVLELTSK 1507
E++E N+ES E+ K+ LE+ +
Sbjct: 750 EEIKE-TNEESSEQIYALKKDLEIAEQ 775
>gb|ETN62597.1| myosin heavy chain, nonmuscle or smooth muscle [Anopheles darlingi]
Length = 2100
Score = 101 bits (251), Expect = 2e-18
Identities = 131/562 (23%), Positives = 229/562 (40%), Gaps = 58/562 (10%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDE---LLNEKDDKKCIVNDRNILE------AAKQALEYKVAD 154
Q LE + D E+ I D L NEK KK VN +++ E A+Q L+ +
Sbjct: 1053 QELEELMQDLESRIEEEEDRVNTLTNEK--KKLQVNIQDLEEQLEEEETARQKLQLEKVQ 1110
Query: 155 LEAAKTTLNDELERKKDDNNAIIK--KALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 328
L+A L ++ +D N+ ++K K L++R +DL + +++ A +
Sbjct: 1111 LDAKLKKLEEDTALIEDQNHKLVKEKKLLEERANDLSQTLAEEEEKAKHLAKLKVKHEST 1170
Query: 329 XXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
++ LE +L H++ Q+ K + ++ K +NE +E +
Sbjct: 1171 ---------IAELEERLLKDHQQRQESDRSKRKIETEVADL---KEQINERRIQIEEMQQ 1218
Query: 509 SL--KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 682
L +E L + + E S + A K RE E S L E E EAEK
Sbjct: 1219 QLVKREEELAQVMVRIDEESTAKAAAQKTQRELE--------SQLAEIQEDLEAEKIARS 1270
Query: 683 KTVLERRASN----------LDTMDAIH-EEELRKEKVDKSALTENGEGCEAEKQGPEKT 829
K ++R N LD++D ++ELR ++ + A + + E E E
Sbjct: 1271 KAEKQKRDLNEELEALKNELLDSLDTTAAQQELRSKREQEVATLK--KTLEDESSNHEAQ 1328
Query: 830 VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTD-----NQEGHEAEIE 994
++D+ ++ L+ + K LEK LEA+NA LT NQ E +
Sbjct: 1329 MMDMRHKHAQEISSINEQLENLKKVKSGLEKSKQTLEAENADLTSELRNVNQSRQENDRR 1388
Query: 995 RK---------------LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV-------L 1108
RK +E + D++ K + + E+I LD + + L
Sbjct: 1389 RKQAETQIAELQVKLAEVERVRVELQDKVTKLQQETENITQQLDEAELKASAAIKSAGNL 1448
Query: 1109 ESKVSDMETTYS-------TLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 1267
ES++++ + L+++L+Q + EA + + E K+ EK++ +L TI
Sbjct: 1449 ESQLTESQQLLEEETRQKLALSSKLRQIESEKEALQEQLEEDEEAKKSYEKKLTELNVTI 1508
Query: 1268 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 1447
Q LKKR E + + + KK+ KDI ++ ELQ
Sbjct: 1509 ------------------QELKKRSDEESDMAKEMEESKKKMNKDIETLQRQIQELQATN 1550
Query: 1448 NKESKEKQDLEKRVLELTSKLE 1513
++ K K+ ++ + + T +LE
Sbjct: 1551 DRLDKSKKKIQSELEDATIELE 1572
Score = 77.0 bits (188), Expect = 3e-11
Identities = 125/566 (22%), Positives = 231/566 (40%), Gaps = 69/566 (12%)
Frame = +2
Query: 32 EATIATLNDELLNEKD-----------------DKKCIVNDRNI-LEAAKQALEYKVADL 157
E+TIA L + LL + D K +N+R I +E +Q L + +L
Sbjct: 1168 ESTIAELEERLLKDHQQRQESDRSKRKIETEVADLKEQINERRIQIEEMQQQLVKREEEL 1227
Query: 158 EAAKTTLNDE---------LERKKDDNNAIIKKALD-KRISDLKADAPQRDQEDDMNALI 307
+++E +R+ + A I++ L+ ++I+ KA+ +RD +++ AL
Sbjct: 1228 AQVMVRIDEESTAKAAAQKTQRELESQLAEIQEDLEAEKIARSKAEKQKRDLNEELEALK 1287
Query: 308 XXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIV 484
+ S E + L + L+ E + A + D+ + ++NE +
Sbjct: 1288 NELLDSLDTTAAQQELRSKREQEVATLKKTLEDESSNHEAQMMDMRHKHAQEISSINEQL 1347
Query: 485 SHLESKSRSLKEHFLREEEDEVLERS----ASNLAIMKAIREEELRKEKDGKSALVE-NG 649
+L+ L E+ + LE S L + R+E R+ K ++ + E
Sbjct: 1348 ENLKKVKSGL------EKSKQTLEAENADLTSELRNVNQSRQENDRRRKQAETQIAELQV 1401
Query: 650 EGCEAEKQGLEK----TVLERRASNLDTMDAIHEEELRKEKVDKSA------LTENGEGC 799
+ E E+ +E T L++ N+ + E EL+ KSA LTE+ +
Sbjct: 1402 KLAEVERVRVELQDKVTKLQQETENITQQ--LDEAELKASAAIKSAGNLESQLTESQQLL 1459
Query: 800 EAEKQGPEKTVLDLE-PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG 976
E E + +K L + I S +ALQ L+ K++ EK+ ++L L +
Sbjct: 1460 EEETR--QKLALSSKLRQIESEKEALQEQLEEDEEAKKSYEKKLTELNVTIQELKKRSD- 1516
Query: 977 HEAEIERKLEASNLTHN----------DELHKEKD----DKESIMNDLDHVKAERQVLES 1114
E+++ +++E S N EL D K+ I ++L+ E + +
Sbjct: 1517 EESDMAKEMEESKKKMNKDIETLQRQIQELQATNDRLDKSKKKIQSELEDATIELETQRT 1576
Query: 1115 KVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI-----E 1279
KV D+E + L ++ +E ERD E + E +VL L + + E
Sbjct: 1577 KVLDLEKKQKNFDKVLAEEKAISEQHAQERDAAEREAREKETKVLSLTRELDEAFEKIDE 1636
Query: 1280 MKTGKDDDYNEAE-----KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 1444
++ + NE + + T K + ELE+A L + +L ++ EL++D
Sbjct: 1637 LEQKRKALQNELDELANTQGTADKNVHELEKAKRALESQLAEL-------KAQNEELEDD 1689
Query: 1445 LNKESKEKQDLEKRVLELTSKLEKCI 1522
L K LE + L ++ E+ I
Sbjct: 1690 LQLTEDAKLRLEVNMQALRAQFERDI 1715
Score = 67.8 bits (164), Expect = 2e-08
Identities = 127/565 (22%), Positives = 235/565 (41%), Gaps = 62/565 (10%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQA--LEYKVADLEAAKTTLN 181
LE EA A L EL N ++ NDR +A Q L+ K+A++E + L
Sbjct: 1357 LEKSKQTLEAENADLTSELRNVNQSRQ--ENDRRRKQAETQIAELQVKLAEVERVRVELQ 1414
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
D++ + + + I ++ LD+ ++LKA A + + + L ++
Sbjct: 1415 DKVTKLQQETENITQQ-LDE--AELKASAAIKSAGNLESQLTESQQ-----------LLE 1460
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHL-----ESKSRSLKEHF 526
L L +L++ + +K AL + L E K++ + ++ L E K RS +E
Sbjct: 1461 EETRQKLALSSKLRQIESEKEALQEQLEEDEEAKKSYEKKLTELNVTIQELKKRSDEESD 1520
Query: 527 LREEEDEVLERSASNL-AIMKAIREEELRKEKDGKSALVENGE----GCEAEKQGLEKTV 691
+ +E +E ++ ++ + + I+E + ++ KS E E E Q +
Sbjct: 1521 MAKEMEESKKKMNKDIETLQRQIQELQATNDRLDKSKKKIQSELEDATIELETQRTKVLD 1580
Query: 692 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
LE++ N D + L +EK + + E E + E VL L L++A
Sbjct: 1581 LEKKQKNFDKV-------LAEEKAISEQHAQERDAAEREAREKETKVLSLTR---ELDEA 1630
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKD 1051
++ +D + +++AL+ +L N T ++ HE E ++ S L ++E +
Sbjct: 1631 FEK-IDELEQKRKALQNELDELA--NTQGTADKNVHELEKAKRALESQLAELKAQNEELE 1687
Query: 1052 DKESIMNDLD-----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE----R 1204
D + D +++A R E + E L + + D EA L+E R
Sbjct: 1688 DDLQLTEDAKLRLEVNMQALRAQFERDIQAKEEQSEEKRRGLVKALRDLEAELDEERKQR 1747
Query: 1205 DGLEAVKQGLEKRVLDLEATIHDIEMKTG-KDDDYNEAEK--QTLKKRISELEEA----- 1360
A K+ LE + DLEAT+ EM K+D +A+K +K I + EEA
Sbjct: 1748 AAAVAAKKKLEGDLKDLEATL---EMNNKVKEDALKQAKKLQAQIKDAIRDAEEAKAAKE 1804
Query: 1361 -ISILTDKAKK--------------------------------LLKDINIWLSEVTELQE 1441
+++++ +A++ LL++IN S+ + + +
Sbjct: 1805 ELAVVSKEAERKVKALEAEFMQLSEDLSSSERARRAAEAERDELLEEINSNSSKGSLMVD 1864
Query: 1442 DLNKESKEKQDLEKRVLELTSKLEK 1516
EK+ LE R+ L +LE+
Sbjct: 1865 -------EKRRLEARIAALEEELEE 1882
Score = 65.5 bits (158), Expect = 9e-08
Identities = 79/333 (23%), Positives = 144/333 (43%), Gaps = 14/333 (4%)
Frame = +2
Query: 593 REEELRKEKDGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEKVD 766
+E+ELR+ +D L + E E + Q + EKT H E + +++
Sbjct: 992 KEDELRQIRDRLDTLSKTSEEYEKKYQQVCDEKT---------------HLAEQLQAEIE 1036
Query: 767 KSALTENGEG-CEAEKQGPEKTVLDLEPTIPSLND---ALQRDLDRVMAEKQALEKRCSD 934
A E G A KQ E+ + DLE I D L + ++ Q LE++ +
Sbjct: 1037 LCAEAEEGRARLSARKQELEELMQDLESRIEEEEDRVNTLTNEKKKLQVNIQDLEEQLEE 1096
Query: 935 LEAKNASLTDNQEGHEAEIERKLEASNLTH--NDELHKEKDDKESIMNDLDHVKAERQVL 1108
E L + +A++++ E + L N +L KEK E NDL AE +
Sbjct: 1097 EETARQKLQLEKVQLDAKLKKLEEDTALIEDQNHKLVKEKKLLEERANDLSQTLAEEEEK 1156
Query: 1109 ESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKT 1288
++ ++ + + EL++++ + +R + K+ +E V DL+ I++ ++
Sbjct: 1157 AKHLAKLKVKHESTIAELEERLLKDH---QQRQESDRSKRKIETEVADLKEQINERRIQI 1213
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILTDK------AKKLLKDINIWLSEVTELQEDLN 1450
E +Q L KR EL + + + ++ A+K +++ S++ E+QEDL
Sbjct: 1214 -------EEMQQQLVKREEELAQVMVRIDEESTAKAAAQKTQRELE---SQLAEIQEDLE 1263
Query: 1451 KESKEKQDLEKRVLELTSKLEKCICGARDGLST 1549
E + EK+ +L +LE D L T
Sbjct: 1264 AEKIARSKAEKQKRDLNEELEALKNELLDSLDT 1296
>ref|XP_005159743.1| PREDICTED: titin isoform X6 [Danio rerio]
Length = 15134
Score = 101 bits (251), Expect = 2e-18
Identities = 132/600 (22%), Positives = 266/600 (44%), Gaps = 39/600 (6%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRN--------ILEAAKQALEYKVADL 157
Q +E A + +N+ L+ E + K ++N++N +++ K LE + DL
Sbjct: 5602 QRVEEMTAQIQKDRDKINN-LIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDL 5660
Query: 158 EAAKTTL---NDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXX 316
E ++ L ++LE++K++ A I+K L+K ++ + + + QE+ MN
Sbjct: 5661 EKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQ----- 5715
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKRTVNEIV 484
+ L+ I L +EL+KEK+ ++ L + + + +N+I+
Sbjct: 5716 ---------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIM 5766
Query: 485 SHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
++++ + L K+ EE+ + +E+ N+ + +E+L+ K K + E E
Sbjct: 5767 ETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLE 5826
Query: 662 AEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTENGEGCEAEKQGPEK 826
K LE+ + R +T + EEL+KE+ D + L E+ + EK ++
Sbjct: 5827 QMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED---TKREKNSLDE 5883
Query: 827 TVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLE 1006
+ E ++ L Q++ + K+ + K+ D+E + D E E+E+ L+
Sbjct: 5884 MKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DKIRLREDELEQ-LQ 5934
Query: 1007 ASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
A E+HK++ + E + +++ ER + V D+++ +L+ + + D E
Sbjct: 5935 A-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE 5984
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI 1342
AF NE++ L+ +K LE+ ++E T H+ EM + N KQ K ++
Sbjct: 5985 AFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKV 6044
Query: 1343 ------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
E+E+ + K L +D+ + ++ L+E+ NK + K LE+ E+ S
Sbjct: 6045 MIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-S 6103
Query: 1505 KLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 1684
K+++ R L + A + E L + RK LD K + +++
Sbjct: 6104 KIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVLDKIKVANESTLAD 6154
Score = 99.8 bits (247), Expect = 5e-18
Identities = 131/591 (22%), Positives = 260/591 (43%), Gaps = 87/591 (14%)
Frame = +2
Query: 5 ALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTT--- 175
A+ V D + + +L+ +L + K D++ N+R +L+ K L+ K ++E K
Sbjct: 4253 AIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQH 4312
Query: 176 -------LNDELERKKDDNNAIIKKA--LDKRISDLKADAPQRDQ--EDDMNALIXXXXX 322
+ ++++++D N +I++ D ++++K + ++ + E D + L
Sbjct: 4313 DRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHD 4372
Query: 323 XXXXXXXXXXIVSNLEVNILILHEELQKEKDDK-------TALIKDLVAAEPGKRTVNEI 481
NLE I E+QKE++D T I D+ E + +
Sbjct: 4373 LEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDE 4432
Query: 482 VSHLESKSRSLKEHFLREEEDEVLERSASNLA-------------IMKAIREEELRKEKD 622
+ L+++ ++L++ +E+E + +RS +L IM+ ++ E + +KD
Sbjct: 4433 LDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKD 4492
Query: 623 GKSALVENGEGCEAEKQG----------------LEKTVLERRASNLDTMDAIHEEELRK 754
K E + E EK L+K VLE S L+ M EL +
Sbjct: 4493 -KEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKI----ELER 4547
Query: 755 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 934
E V+ + E + E+Q EK L+ L + +++ + K A E +D
Sbjct: 4548 EAVEIRKIKEE---IQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLAD 4604
Query: 935 LEAKNASLTDNQEG---HEAEIERKLEASNLTHND------ELHKEKDDKESIMNDLDHV 1087
+ + ++L + +E ++E K E L ++ E+HK++ + E + ++
Sbjct: 4605 ILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEK---EKINI 4661
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE--- 1258
++ER + V D++ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 4662 ESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIK 4721
Query: 1259 -ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AK 1387
T HD +++ +D+ N E+ L ++ ++EE I SI +DK +
Sbjct: 4722 LETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLE 4781
Query: 1388 KLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 1516
K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 4782 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 4832
Score = 99.4 bits (246), Expect = 6e-18
Identities = 124/547 (22%), Positives = 230/547 (42%), Gaps = 48/547 (8%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 217
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 4152 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 4211
Query: 218 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEE 397
K+ R+ + + + Q + + V +L+ + L +
Sbjct: 4212 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 4271
Query: 398 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 553
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 4272 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 4324
Query: 554 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 706
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 4325 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 4384
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 865
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 4385 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 4444
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 4445 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 4504
Query: 1040 KEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
KEK D ++S+ DL +K ++QVLE + S +E L E + E NER
Sbjct: 4505 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 4564
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 1369
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 4565 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 4621
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 1525
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 4622 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 4681
Query: 1526 GARDGLS 1546
RD S
Sbjct: 4682 LDRDAES 4688
Score = 94.0 bits (232), Expect = 2e-16
Identities = 133/541 (24%), Positives = 243/541 (44%), Gaps = 54/541 (9%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 5212 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 5271
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5272 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5310
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5311 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5368
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 718
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 5369 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 5428
Query: 719 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 883
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 5429 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 5477
Query: 884 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1057
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 5478 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINI 5534
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
ES ER + V D++ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 5535 ES----------ERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 5584
Query: 1238 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 1363
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 5585 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 5644
Query: 1364 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 1513
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 5645 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 5704
Query: 1514 K 1516
+
Sbjct: 5705 E 5705
Score = 91.3 bits (225), Expect = 2e-15
Identities = 102/535 (19%), Positives = 239/535 (44%), Gaps = 32/535 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 4461 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4520
Query: 188 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXXI 355
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 4521 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 4580
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 529
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 4581 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 4640
Query: 530 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 667
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 4641 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 4699
Query: 668 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
K+ L+ KT LER A ++ + E + +++V++ A + E E D+
Sbjct: 4700 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 4757
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLT 1021
+ N ++ + + ++K LEK DLE + L +E E + E L
Sbjct: 4758 --VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA----- 4810
Query: 1022 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
E+ KE++D E+I ++ +K + + + K +++ + + N Q+ + E
Sbjct: 4811 ---EIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 4867
Query: 1190 FLNERDGLEAVKQGLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEA 1360
+ +R L+ + L+K+ + D+ T+ + + KD + E +KQ ++K ++++
Sbjct: 4868 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 4927
Query: 1361 ISILTDKAKKLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
L + KK+ ++ E +L++ +L +E+ E +++ +LEK
Sbjct: 4928 RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 4982
Score = 90.1 bits (222), Expect = 4e-15
Identities = 127/548 (23%), Positives = 237/548 (43%), Gaps = 49/548 (8%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 166
+ LE+ + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3639 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3698
Query: 167 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 313
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3699 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3752
Query: 314 XXXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 475
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3753 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3796
Query: 476 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3797 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3851
Query: 653 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 808
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3852 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3905
Query: 809 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 979
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3906 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQ 3965
Query: 980 -EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 1156
+AEI ++ E+ KEK + ES ER + V D++ +L+
Sbjct: 3966 LQAEIHKQQR--------EIEKEKSNIES----------ERAAIIKIVEDLQHKIISLDR 4007
Query: 1157 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIEMKTGKDDDYNEA--- 1315
+ + D EAF NER+ L+ +K LE+ ++E T H+ + D+ E
Sbjct: 4008 DAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHERQRVEEMTADFMETMNN 4067
Query: 1316 -------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 1474
K+ ++++ E+E+ + K L K++ + + ++E+ NK + K +
Sbjct: 4068 ERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIE 4127
Query: 1475 LEKRVLEL 1498
LEK E+
Sbjct: 4128 LEKEADEI 4135
Score = 89.4 bits (220), Expect = 6e-15
Identities = 114/525 (21%), Positives = 236/525 (44%), Gaps = 44/525 (8%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE K LE YKV DLE K E++++
Sbjct: 4756 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKE 4815
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 4816 REDLEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 4854
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 4855 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 4912
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT------VLER 700
+ + +E+ N+ + +E+ +K K K E E K LE+ + E
Sbjct: 4913 QKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEE 4972
Query: 701 RASNLDTMDAIHEEELRKE----------KVDKSALTEN---GEGCEAEKQGPEKTVLDL 841
+ ++ + EE +R++ K +K L E E A+ Q + + ++
Sbjct: 4973 TQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEM 5032
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNL 1018
I L + + + ++ + L+K ++++ + + + + E+E + E N+
Sbjct: 5033 RENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNM 5092
Query: 1019 THNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
EL K+ +D E I+ + + + +R++L V +++ L + ++ D E
Sbjct: 5093 M--TELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 5150
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS 1366
AF NE++ ++ +K L+ + ++E I+++T D E ++K ++ I
Sbjct: 5151 AFENEKEAMKQMKTDLQIQADEIE----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE 5206
Query: 1367 ILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLEL 1498
T++ +L + N + E + +Q D + KE+ +LEK EL
Sbjct: 5207 -ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSEL 5250
Score = 87.8 bits (216), Expect = 2e-14
Identities = 122/538 (22%), Positives = 233/538 (43%), Gaps = 24/538 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E++ E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 182 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 340
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 520
I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 521 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 682
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 683 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 832
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1009
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1010 SNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
++++ +++L KE+ ++E I N +K E LE ++ NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 1190 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 1369
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 1543
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 85.9 bits (211), Expect = 7e-14
Identities = 116/534 (21%), Positives = 238/534 (44%), Gaps = 34/534 (6%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLND 184
K+ + + +A L+ EL KD+ + I +R+ +E + L ++ +E + D
Sbjct: 9116 KMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQD 9175
Query: 185 ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSN 364
+ ++ +I +K + +I + + Q +QE N L I N
Sbjct: 9176 KQNHLEEKELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELN 9232
Query: 365 LEVN------ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK 502
+ N + + EL+ EK D K + L E K + ++ L+SK
Sbjct: 9233 KQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSK 9292
Query: 503 -SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
++ KE + ++R + + + + + + K+ L E E + E++ L
Sbjct: 9293 REQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKL 9352
Query: 680 E--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E K +++ A NL+ + + + K ++ ++ L E CE ++ E+ D+E I
Sbjct: 9353 EEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQI 9412
Query: 854 PSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EAS 1012
+ +A L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +
Sbjct: 9413 QNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKA 9472
Query: 1013 N--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL---QQKMD 1177
N L D+L KEK+D N LD ++ E Q + +++ NE+ QQ+++
Sbjct: 9473 NEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLE 9532
Query: 1178 DNEAFLNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 1354
++ +NE G LE ++ EK+ +E + +M E++ L + SELE
Sbjct: 9533 ESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELE 9581
Query: 1355 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ + + + KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 9582 KDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 9635
Score = 85.5 bits (210), Expect = 9e-14
Identities = 103/492 (20%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = +2
Query: 71 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 238
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 239 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDD 418
+R+++++ + +++ D+ ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 419 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 598
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 599 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 778
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 779 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 958
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 959 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETT 1138
+ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 1309
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 1310 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 1453
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1454 --ESKEKQDLEK 1483
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 82.4 bits (202), Expect = 7e-13
Identities = 111/556 (19%), Positives = 242/556 (43%), Gaps = 54/556 (9%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL----------- 157
EN + E + +++ N ++ K + +R ++ KQ L+ + DL
Sbjct: 9395 ENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENV 9454
Query: 158 EAAKTTLNDELERKKDDNNAIIKKA--LDKRISDL-----KADAPQRDQEDDMNALIXXX 316
E +K +L++E + + N I+++ L+K D+ K D Q + +++ A+
Sbjct: 9455 EMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIK 9514
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEE------LQKEKDDKTALIKDL-VAAEPGKRTVN 475
LE ++ ++EE ++ + + + I+++ V A+ ++ ++
Sbjct: 9515 YELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELD 9574
Query: 476 EIVSHLESKSRSLKEHFLREEEDE-VLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I S LE + + + D ++E+ ++L MK+ + ++ +D +S L + +
Sbjct: 9575 QIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIK 9634
Query: 653 GCEAEKQGLEKT--VLERRASNLDTMD---AIHEEELRKEK---VDKSALTENGEGCEAE 808
EK +EK ++ER + ++ + +EEL E+ VD+ L CE E
Sbjct: 9635 EANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQ---CETE 9691
Query: 809 KQGPEKTVLDLEPTIPSLNDAL-------QRD-------LDRVMAEKQALEKRCSDLEAK 946
Q + + ++E + + + L QRD ++ +K+ LEK + + +
Sbjct: 9692 LQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQ 9751
Query: 947 NASLT---DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLES- 1114
L D E EI K ++ + + KE + + ++ ER+ LE
Sbjct: 9752 KQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEV 9811
Query: 1115 --KVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKT 1288
K+ +M+T ++E+ QK+++ L+ +++ + K EA ++M
Sbjct: 9812 NGKIIEMKTKAELEHHEINQKIEE----------LQTLQEQIMKEKEKAEAMTIKLKM-- 9859
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEK 1468
E++ L + SEL + + + KKL DI + E +L++ ++ +K
Sbjct: 9860 ---------EREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 9910
Query: 1469 QDLEKRVLELTSKLEK 1516
Q++EK EL +K+++
Sbjct: 9911 QEMEKERSELDNKIQQ 9926
Score = 82.0 bits (201), Expect = 1e-12
Identities = 117/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N ++ E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 8800 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 8859
Query: 188 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 343
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 8860 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 8918
Query: 344 XXXIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 514
L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 8919 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 8973
Query: 515 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 8974 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9033
Query: 680 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9034 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9092
Query: 854 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1030
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9093 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 9147
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 1210
E H+ + + + + + ++ + Q+++ K + +E ++ + ++ N F E++
Sbjct: 9148 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 9207
Query: 1211 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 1390
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 9208 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 9253
Query: 1391 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 1516
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 9254 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 9295
Score = 81.3 bits (199), Expect = 2e-12
Identities = 121/518 (23%), Positives = 225/518 (43%), Gaps = 20/518 (3%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + E +L+ +DDK + NDR+ E LE K
Sbjct: 8607 QDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELK-----------R 8655
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+EL R+ +D + +K L +R D + +RD E+ AL
Sbjct: 8656 EELVRETED---LERKILQQREQD---EMAKRDIENQTEAL------------------E 8691
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
++V+IL E KE ++ V +E K + + L+S+ L+ EE+
Sbjct: 8692 VMKVDILKKRNEFAKEMEN--------VHSERQKLLL--LQGALQSQESELENRVFMEEQ 8741
Query: 542 DEVLERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
+ + A K + E E + E++ L+E + E E+ + K +E+ +L
Sbjct: 8742 KHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR-EKEQLEISKNQIEQEKKDL 8800
Query: 716 DTMDAIHE---EELRKEKV----DKSALTENGEGCEAEKQGPEKTVLDLE---PTIPSLN 865
M + E E LR EK +K+AL + + + K DLE I
Sbjct: 8801 QNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEK 8860
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
++ + R+ ++ ++K S+L+ ++ +E ++E +++ +E+
Sbjct: 8861 KRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIE 8920
Query: 1040 KEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 1219
KE + DL++ KAE Q E K D+ ++ ++Q+K + + L++ +
Sbjct: 8921 KESQRLQDATIDLENAKAEIQRQEDKFEDI------IDIKIQEKEREIKIQLDKE--TKR 8972
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKK 1390
+ + +E +V DLE + D++ + + +D E EKQ LK+ ELE+ + LT + ++
Sbjct: 8973 LSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQE 9032
Query: 1391 LLKDINIWLSEVTELQEDLNKES---KEKQDLEKRVLE 1495
++ N ++ +L EDL KE+ KEK LEK +E
Sbjct: 9033 TEEERNNLMALKNQL-EDLRKENEIVKEKLTLEKSNIE 9069
Score = 80.9 bits (198), Expect = 2e-12
Identities = 111/536 (20%), Positives = 231/536 (43%), Gaps = 46/536 (8%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 11493 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 11552
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 11553 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 11612
Query: 362 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 11613 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 11672
Query: 509 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 664
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 11673 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 11727
Query: 665 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 811
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 11728 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 11787
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 11788 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 11847
Query: 992 --ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 11848 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 11907
Query: 1154 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 1318
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 11908 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 11963
Query: 1319 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 1480
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 11964 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12016
Score = 80.1 bits (196), Expect = 4e-12
Identities = 94/521 (18%), Positives = 225/521 (43%), Gaps = 46/521 (8%)
Frame = +2
Query: 92 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 244
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 11161 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 11220
Query: 245 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEEL 400
I ++K ++++E+ M A + I S LE + E
Sbjct: 11221 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 11274
Query: 401 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 580
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 11275 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 11333
Query: 581 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 706
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 11334 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11393
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 11394 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 11449
Query: 887 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1033
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 11450 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 11509
Query: 1034 LHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGL 1213
+ KEK+ +E V+ ER+ +E S +E S +++E ++ DD + E++ L
Sbjct: 11510 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 11569
Query: 1214 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 1393
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 11570 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 11628
Query: 1394 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 11629 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 11669
Score = 79.3 bits (194), Expect = 6e-12
Identities = 122/575 (21%), Positives = 250/575 (43%), Gaps = 74/575 (12%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K+ E T +++ EK+ ++ V R +E K+ L+ + LE ++ ++ E
Sbjct: 10938 ETKIKIIEMKTKTEPEKIKKEKEKEEEEVM-RAKVEMKKEELDQIKSQLERVRSEIDHEQ 10996
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 10997 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQ 11056
Query: 362 NLEV-------NILILHEEL----QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V +I + EEL QK D++ ++++ + + E+ ++ +
Sbjct: 11057 KLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKE 11116
Query: 509 SLKE---HFLREEED-------------EVLERSASNLA-----------IMKAIREE-- 601
+LKE H +E+E+ E LE+ ++++ ++K REE
Sbjct: 11117 TLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEIN 11176
Query: 602 ----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE--KV 763
+L++ D A V + + KQ K + E R S +T I E + + E K+
Sbjct: 11177 HKWTQLQQRIDEFDAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKI 11233
Query: 764 DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEA 943
K E E A+ + ++ + ++ + + + + ++ +K+ +E+ DLE
Sbjct: 11234 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11293
Query: 944 KNASLTDNQEGHE---AEIERKLEASNLTHND-ELHKE---------KDDKESIMNDLDH 1084
+ + ++ E +E+E K+ + + D E KE ++ K I +
Sbjct: 11294 MKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEE 11353
Query: 1085 VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEAT 1264
+ ERQ + + + S L NE ++ + NE ER+ L+ ++ LEK ++++
Sbjct: 11354 LDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI 11413
Query: 1265 IHDIEMKTGKDD-----DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVT 1429
E + K+D + +KQ L+ + LE+ + K K+L + I+ + ++V+
Sbjct: 11414 TE--ETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 11471
Query: 1430 -ELQEDLNKESKEKQD------LEKRVLELTSKLE 1513
+ +EDL KE + K+D + +LE+ +K E
Sbjct: 11472 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAE 11506
Score = 78.6 bits (192), Expect = 1e-11
Identities = 115/572 (20%), Positives = 245/572 (42%), Gaps = 91/572 (15%)
Frame = +2
Query: 56 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 193
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 5858 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 5917
Query: 194 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 331
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 5918 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 5977
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 499
N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 5978 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6034
Query: 500 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 676
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6035 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6094
Query: 677 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 808
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6095 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 6154
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 988
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 6155 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 6214
Query: 989 IERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
+ E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 6215 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 6272
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 1294
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6273 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 6332
Query: 1295 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 1420
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 6333 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 6388
Query: 1421 EVTELQEDLNKESKE------KQDLEKRVLEL 1498
E+ + + L K SKE K + EK+ ++L
Sbjct: 6389 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 6420
Score = 77.8 bits (190), Expect = 2e-11
Identities = 108/524 (20%), Positives = 230/524 (43%), Gaps = 31/524 (5%)
Frame = +2
Query: 38 TIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL---NDELERKKDD 208
T+ + L EK++ K I + K+ LE D++ L D LE++K+D
Sbjct: 10003 TLKEMEAHLEKEKEEMKSITEETR---RQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKED 10059
Query: 209 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILIL 388
N + L +RI + A ++ +ED I + + +
Sbjct: 10060 INHEWTQ-LQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDI 10118
Query: 389 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE--VLERS 562
+E +KE++++ +K E + ++ I S L+ + RS +H ++ D+ ++E+
Sbjct: 10119 KKEKEKEEEEEEMRVK----VEMDGKELDRIKSELK-RERSEIDHEQKKLNDDKKIIEQE 10173
Query: 563 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE 742
NL MK+ ++ ++ ++ +S L + EK +E + + ++ + HE
Sbjct: 10174 KQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEI 10233
Query: 743 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 922
+ +KE++D E+Q + D + + LQ + +R+ + ++K
Sbjct: 10234 QFQKEELD------------IERQ----KIADEQDLLIQNKSELQNENERIRNLNEIIKK 10277
Query: 923 RCSDLEAKNASLTDNQEGHEAEIE--RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAE 1096
L+ A L +E ++ E R+L+ + +++K+ D +MN D ++ E
Sbjct: 10278 ERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKD---LMNQRDLLEQE 10334
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IH 1270
R+ + K +LQQ++D+ +A ++++ + K+ G+++ LE T +
Sbjct: 10335 REEINHKWK-----------QLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 10383
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL------------------ 1396
IEMKT + + + EK+ + E EE I ++ + +K L
Sbjct: 10384 VIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQ 10443
Query: 1397 KDINIWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEK 1516
K +N ++ + + +EDL K K++Q +E+ EL +K+++
Sbjct: 10444 KKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQ 10487
Score = 76.6 bits (187), Expect = 4e-11
Identities = 112/520 (21%), Positives = 215/520 (41%), Gaps = 22/520 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA------- 166
+EN F+ IA L + K DK+ I N+ L+ +Q E + + +
Sbjct: 14154 IENITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYD 14213
Query: 167 -----KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 331
KT L D E+KK D ++ +K ++D AD+ + D E + L
Sbjct: 14214 EKVTYKTELEDSKEKKKPDRDSSLK------LTD--ADSAKTDGEREAQTL--------- 14256
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
V L EEL E ++K +I +L A+ + + L+ + RS
Sbjct: 14257 --ETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAK-------KDLQKLKEECRS 14307
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KT 688
+E + E LER ++L E+++ E + +++ + E Q +E K
Sbjct: 14308 AEEE--KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKM 14357
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPS--- 859
++ R+ + ++ ++ +T+ E + K+ + TV LE T+ S
Sbjct: 14358 QIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQ 14417
Query: 860 -LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDEL 1036
+ D+L ++++ V K ++ LE + + E E +E +E + + ++L
Sbjct: 14418 EMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKL 14476
Query: 1037 HKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER 1204
+ DKE + N LD ++ + K++ +ETT + +
Sbjct: 14477 LQLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETTIVLMKKD--------------- 14521
Query: 1205 DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDK 1381
K+ +E +L L+ T + E++ G DD NE EK K +ELE+ +
Sbjct: 14522 ------KENIENELLQLKQTEQEREIQRGTDDTSNEREKYDEKVTYKTELED-----NKE 14570
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
KK +D ++ L++ + D +E++ + + VL+LT
Sbjct: 14571 KKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 14610
Score = 76.3 bits (186), Expect = 5e-11
Identities = 125/547 (22%), Positives = 241/547 (44%), Gaps = 47/547 (8%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT---TLNDE 187
K+AD + + EL NE + I N I++ ++ L+ A LE K ++++E
Sbjct: 10246 KIADEQDLLIQNKSELQNENER---IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEE 10302
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R K+D L+K +D+ +D + + L +
Sbjct: 10303 TRRLKED--------LEKMSTDVNKQ--NKDLMNQRDLLEQEREEINHKWKQLQQRIDEF 10352
Query: 368 EVNILILHEE-LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES---KSRSLKEHFLRE 535
+ + E+ L KEK K +D + E K V E+ + E K KE+ E
Sbjct: 10353 DAQVSKQKEQDLPKEKGMK----EDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEE 10408
Query: 536 EEDE----VLERSASNLAIMKAIREEELRKEKDGKSA-LVENGEGCEAEKQGLEKTV--- 691
EE+E ++E L +K+ E +R E D + L + + E EK+ LEK
Sbjct: 10409 EEEEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEI 10467
Query: 692 ------LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDL 841
+E S LD + I + L K ++KS E E+Q + K LD+
Sbjct: 10468 MKQRQQMEEERSELD--NKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDI 10525
Query: 842 E-PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNL 1018
E I + L ++ ++ E + ++K +++ + +L E EI K E L
Sbjct: 10526 ERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETL------REMEIHLKKEKEEL 10579
Query: 1019 THN-DELHKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 1183
+E + K+D E + D++ H+K +R +LE + ++ + +LQQ++D+
Sbjct: 10580 RSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT----QLQQRIDEF 10635
Query: 1184 EAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDIEMKTGKDDDYN-----EA 1315
+A +++ + +E ++ LE+ R+++++ A + +I + ++D+ E
Sbjct: 10636 DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVEM 10695
Query: 1316 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 1495
E++ L + SEL+ S + + KKL D I E +L++ ++ ++Q +E+ E
Sbjct: 10696 EREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSE 10755
Query: 1496 LTSKLEK 1516
L +K+++
Sbjct: 10756 LDNKIKQ 10762
Score = 75.9 bits (185), Expect = 7e-11
Identities = 111/513 (21%), Positives = 213/513 (41%), Gaps = 67/513 (13%)
Frame = +2
Query: 179 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXI 355
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 535
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 536 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 682
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 683 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 805
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 806 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 928
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 929 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAE 1096
DL+ + A + +E E+E+ + N D E K E D K ++ + ++++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 1276
R+++E + +E L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 1277 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 1417
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 1418 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 75.5 bits (184), Expect = 9e-11
Identities = 110/522 (21%), Positives = 225/522 (43%), Gaps = 35/522 (6%)
Frame = +2
Query: 5 ALENKVADFE---ATIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEA 163
A + + DFE I N EL ++++ K + + R LE + + +V +
Sbjct: 6599 AFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITN 6658
Query: 164 AKTTLND---ELERKKDD-----------NNAIIKKA--LDKRISDLKADAPQRDQEDDM 295
+L+ EL + ++D N I+ + LD+R SD+ D Q++ +D M
Sbjct: 6659 ENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQKEVDDLM 6716
Query: 296 NALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVN 475
+ ++N+E L + + + K D +L + A E + +N
Sbjct: 6717 D--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLN 6762
Query: 476 EIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E +E + L ++ ++D++ ++R NL + K + E ++ + K +L
Sbjct: 6763 EEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAI 6822
Query: 653 GCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ 814
G + +EK E+ ++E A+ LD + E + +E++D++ +
Sbjct: 6823 GFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLF 6882
Query: 815 GPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 994
EKT DL+ T +N D + + ++ L K E E
Sbjct: 6883 QEEKT--DLQKTKEEIN----YDREEIYRQRTELNK-------------------EKETL 6917
Query: 995 RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKM 1174
+++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + + E +
Sbjct: 6918 KQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELA 6974
Query: 1175 DDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ---TLKKRIS 1345
D E NE+D L+ ++ ++K + +L+ E + + N+ +Q +K +
Sbjct: 6975 RDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTEEIKLKND 7028
Query: 1346 ELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 1465
L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7029 SLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7070
Score = 75.5 bits (184), Expect = 9e-11
Identities = 105/540 (19%), Positives = 219/540 (40%), Gaps = 57/540 (10%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 12812 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 12861
Query: 221 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEV 373
+ AL+K + DL+ + +++NAL+ E
Sbjct: 12862 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 12902
Query: 374 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 532
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 12903 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 12961
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 12962 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13015
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 892
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13016 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13075
Query: 893 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1042
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13076 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13134
Query: 1043 EKDDKESIMNDL----------------------------DHVKAERQVLESKVSDMETT 1138
EKD E I DL D + + + L S +D+E
Sbjct: 13135 EKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQ 13194
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 13195 AKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDLT 13236
Query: 1319 KQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL ++
Sbjct: 13237 LQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQL 13296
Score = 74.3 bits (181), Expect = 2e-10
Identities = 122/611 (19%), Positives = 247/611 (40%), Gaps = 64/611 (10%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELER 196
+V + L E+ ++ K ++++ I ++ Q L + + L E+E
Sbjct: 8201 EVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIEN 8260
Query: 197 KKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVN 376
K D K L+K ++L + Q+++E L ++E++
Sbjct: 8261 TKRD-----KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEIS 8313
Query: 377 ILILHEEL-----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES-------- 499
++ E+ QK K++ + ++L+ + +N V HL
Sbjct: 8314 RELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQ 8373
Query: 500 --KSRSLKEHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDG 625
K ++ EH E + +++LE+ L +++I E L+K +D
Sbjct: 8374 YIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED- 8432
Query: 626 KSALVENGEGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGE 793
+ + E EKQ E + L+R+ +++ I E++ K K+D E
Sbjct: 8433 ---MEKEKENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSA 8488
Query: 794 GCEAEKQGPEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEA 943
E E + E DLE SLNDA LQ+ + + EK+ +E+ ++
Sbjct: 8489 AFEKEHKRLENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKT 8548
Query: 944 KNASLTDNQE-----------GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD-HV 1087
+ + +E GHE ++++K E + D+L ++ + + + DL +
Sbjct: 8549 ERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKL 8602
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 1267
+ +RQ +E ++MET +L+ ++ DD N+RD E LE + +L
Sbjct: 8603 QMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRET 8662
Query: 1268 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 1447
D+E K + + +E K+ ++ + LE + K + K++ SE +L
Sbjct: 8663 EDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQ 8722
Query: 1448 NKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGF 1624
++ +LE RV +E L++ + + E MS+ + + + L++
Sbjct: 8723 GALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEEL 8779
Query: 1625 SRKTSPLDITK 1657
R+ L+I+K
Sbjct: 8780 QREKEQLEISK 8790
Score = 73.6 bits (179), Expect = 3e-10
Identities = 109/526 (20%), Positives = 232/526 (44%), Gaps = 23/526 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N+ D E + + DE N + K+ + +DR+ LE + DLE KT + +
Sbjct: 3046 LQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKER-------FDLEKTKTEMGN- 3097
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
+KK L+ +I + + +E + I+ L
Sbjct: 3098 -----------LKKQLESQIRQHEIQLVEIQKERE--------------------ILEQL 3126
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKSRSLKEHFLREEED 544
++N+ E+L+KE+D D+ +E K ++ E + + ++ +++E D
Sbjct: 3127 KINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTR--------IKQEMD 3178
Query: 545 EVLERSASNLA-------IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 703
E LE++ NLA + K I E+E K + K+ L + E + E Q E+ LE
Sbjct: 3179 E-LEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQN-ERQNLEEA 3236
Query: 704 ASNL----DTMDAIHEEELRKEKVDKSALTE---NGEGCEAEKQGPEKTVLDLEPTIPSL 862
+ L + ++++ EE RK+ V ++ E + E+ KQ E+ +++L+ T+ +
Sbjct: 3237 GTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTVTDI 3296
Query: 863 NDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHK 1042
A + ++++ E++ + + ++++A+ L ++G E++++ N T L +
Sbjct: 3297 AGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGIS---EQQVDIVNKTEQLRLRE 3353
Query: 1043 EKDD--KESIMNDLDHVKAERQVL---ESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
+ + + I D ++A R+ + + ++ +T L E+ Q M+ +D
Sbjct: 3354 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMME-----YASKD 3408
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAK 1387
+ LEK ++ A H ++++ K+ E Q L E+++ + L + K
Sbjct: 3409 -----RANLEKEKSEMIAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMK 3463
Query: 1388 KLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
+L E +LQ+ +L +E+ + + L+++ LEK
Sbjct: 3464 ELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEK 3509
Score = 72.8 bits (177), Expect = 6e-10
Identities = 117/569 (20%), Positives = 233/569 (40%), Gaps = 66/569 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAK 169
Q+ + + + + T+ L DE +++ + N+ ++ K +LE ADL+
Sbjct: 13091 QSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRKA 13150
Query: 170 TTLNDELERKKDDNNAIIKKAL--------DKRISDLKADAPQRDQ--EDDMNALIXXXX 319
L++E+ + + I + A ++ + ++AD ++ + E D+ L
Sbjct: 13151 EKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKE 13210
Query: 320 XXXXXXXXXXXIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 487
+ +LE N L L +EL+KEK +I D+ + + V+
Sbjct: 13211 ILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------DAVA 13262
Query: 488 HLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 13263 SLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR 13321
Query: 662 AEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTENGE 793
+ + ++ + E R D + DA+ + +EL K D E+ E
Sbjct: 13322 NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVE 13381
Query: 794 GCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA------- 943
E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 13382 KEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKT 13441
Query: 944 -----KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH--- 1084
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 13442 LVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEV 13501
Query: 1085 ------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGLEKR 1243
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +E
Sbjct: 13502 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE-- 13559
Query: 1244 VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 1423
+EKQ++++ +EL K+L +++ + E
Sbjct: 13560 -----------------------SEKQSIERERAEL-----------KRLKEEVEVQ-HE 13584
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKL 1510
T LQ+D N KEK+ LE T ++
Sbjct: 13585 RTLLQQDKNMIQKEKEHLEGEKARTTEEI 13613
Score = 71.6 bits (174), Expect = 1e-09
Identities = 107/531 (20%), Positives = 221/531 (41%), Gaps = 28/531 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
++ ++ + E T + EL N + K+ I ++R+ +E K L+ + D E + + ++
Sbjct: 2779 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2838
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++++ +IK +K+ + D + +
Sbjct: 2839 ---RRNNEEMVIKLQNEKKDIETSTDR-----------------------------IRDE 2866
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEED 544
E N+ +L + L+ ++D L K+ + + ++ LES++R + ++E
Sbjct: 2867 EANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKER 2923
Query: 545 EVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
E+LE+ L+ K E+E KEK S E E ++E++G+ KT R
Sbjct: 2924 EILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIK 2977
Query: 716 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 895
MD EL++ +++ EN E +KQ ++ + D++
Sbjct: 2978 KEMD-----ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKI 3011
Query: 896 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDK 1057
K L+K D E + + ++ +E + ++ +E S DE + K
Sbjct: 3012 EQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQK 3071
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
+ + +D D ++ ER LE ++M L ++++Q ER+ LE +K L
Sbjct: 3072 QRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLS 3131
Query: 1238 KRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL---- 1372
K+ DLE E + +D ++E++ +K+ + ELE+ L
Sbjct: 3132 KQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQ 3191
Query: 1373 --TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3192 ENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 71.6 bits (174), Expect = 1e-09
Identities = 111/536 (20%), Positives = 234/536 (43%), Gaps = 60/536 (11%)
Frame = +2
Query: 86 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERK-KDDNNAIIKKALDKRISD 253
K + NDRN++E + LE ++L + + DE L++K K+ N K +K I +
Sbjct: 9592 KKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVE 9651
Query: 254 LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKE----KDDK 421
+ A +Q +D +++ E + E+++ K+++
Sbjct: 9652 -RLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNER 9710
Query: 422 TALIKDLVAAEPGKRTVNEIVSHLESKSRSL----------------KEHFLREEEDEV- 550
L + + K+ + I+ + L K+ L +E +E+
Sbjct: 9711 ETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEIN 9770
Query: 551 ------LERSASNLAIMKAIREEELRKEK---DGKSALVE-NGEGCEAE-KQGLEKTVLE 697
+R A ++ +EE+L +K + + L E NG+ E + K LE +
Sbjct: 9771 HKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEIN 9830
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT-IPSLNDAL 874
++ L T+ +E++ KEK A+T + E E K+ L E T + L
Sbjct: 9831 QKIEELQTL----QEQIMKEKEKAEAMTIKLK-MEREDLDQIKSELVREKTEVDHEQKKL 9885
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
D+ + EK+ LEK S++ + + E +E++ K++ ++L +D + K K+
Sbjct: 9886 NDDIKMIEQEKEDLEKMKSEIMTQKQEM----EKERSELDNKIQQTDLEKHD-IEKSKEI 9940
Query: 1055 KESIMNDLDHVKAERQVLES-------KVSDMETTY----STLNNELQQKMDDNEAFLNE 1201
E +M +++ + E Q+ + K++D + S L NE ++ + NE E
Sbjct: 9941 VEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKE 10000
Query: 1202 RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------DYNEAEKQTLKKR--ISELEE 1357
R+ L+ ++ LEK ++++ E + K+D D E + +K+R + + +E
Sbjct: 10001 RETLKEMEAHLEKEKEEMKSITE--ETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKE 10058
Query: 1358 AISILTDKAKKLLKDINIWLSEVTE----LQEDLNKESKEKQDLEKRVLELTSKLE 1513
I+ + ++ + + + +S+ E Q+++ +E K ++ + R++E+ +K E
Sbjct: 10059 DINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAE 10114
Score = 71.6 bits (174), Expect = 1e-09
Identities = 109/563 (19%), Positives = 243/563 (43%), Gaps = 50/563 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LER 196
D E+ L++E +D+ K + +N+L +K + +LE T + E +E+
Sbjct: 13323 DLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEK 13382
Query: 197 KKDD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXX 346
++++ N IIK ++L+ I K + A +R Q + + L
Sbjct: 13383 EREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTL 13442
Query: 347 XXIVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
+ + + L LQK+K++ L ++ + AE K V L+ + +
Sbjct: 13443 VQTEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQK 13499
Query: 509 SLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----E 661
+++ + + E +VLE+ S L + + E++++E++ L+E E C E
Sbjct: 13500 EVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE 13559
Query: 662 AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
+EKQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L
Sbjct: 13560 SEKQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNL 13616
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQ 970
+ I + L + A++Q E K+ D+ E TD
Sbjct: 13617 KEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDAS 13676
Query: 971 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL----ESKVSDMETT 1138
+ + + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 13677 QKFQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEM 13735
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
LNNE+++ E+D L+ K ++ ++ + E + + + +++
Sbjct: 13736 RDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE------ 13789
Query: 1319 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 1498
+ L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 13790 -EKLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQL 13848
Query: 1499 TS-KLEKCICGARDGLSTIKEAW 1564
+ E+ I D ST KE +
Sbjct: 13849 KQIEQEREIQRKADVTSTEKEMY 13871
Score = 70.9 bits (172), Expect = 2e-09
Identities = 107/548 (19%), Positives = 230/548 (41%), Gaps = 46/548 (8%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ K ++ + +ND + K+++K + D+ +E K+ +E + D + + +L+++
Sbjct: 3781 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 188 LERKK-------DDNNAI--IKKALDKRISDLKADAPQRDQE--------DDMNALIXXX 316
L+ K ++ N + +K L++ +++ + E +++
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLE 496
I+ ++V L ELQKEK + + +++ + E + E
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3960
Query: 497 SKSRSLKEHFLREEEDEVLERS------ASNLAIMKAIREEELRKEKDGKSALVENGEGC 658
+ L+ +++ + E+S A+ + I++ ++ + + ++D +S ++ E
Sbjct: 3961 DELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRDAESLKLDR-EAF 4019
Query: 659 EAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKV---------DKSALTENGEGC 799
E E++ L+ KT LER ++ ++ HE + +E ++ L +N E
Sbjct: 4020 ENEREVLKQMKTELERETDEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEM 4079
Query: 800 EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGH 979
+ +KQ EK D++ + SL+ ++L + +KQ +E+ + LE L
Sbjct: 4080 QEQKQEMEKERHDMDQSRKSLD----KNLKMMKLQKQVIEEEKNKLEQMKIELEK----- 4130
Query: 980 EAEIERKLEASNLTHNDELHKE----KDDKESIMNDLDHVKAERQVLESKVSDMETTYST 1147
EA+ RK++ L K K +KES + + K E+++L+ M+ +
Sbjct: 4131 EADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDK----MKVANES 4186
Query: 1148 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQT 1327
L +LQ+ E+ LE +++ + K+ D +E EK+
Sbjct: 4187 LMADLQK----------EKSNLEEMRENISKQTED------------------SEKEKEK 4218
Query: 1328 LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKES------KEKQDLEKRV 1489
++ R ELE+ L +I+ E+ E N ES K+ +DL+ ++
Sbjct: 4219 IRLREDELEQ-----------LQAEIHKQQGEIK--MEKSNNESERAAIIKDVKDLQHKM 4265
Query: 1490 LELTSKLE 1513
L LE
Sbjct: 4266 FSLDRDLE 4273
Score = 70.9 bits (172), Expect = 2e-09
Identities = 120/625 (19%), Positives = 268/625 (42%), Gaps = 75/625 (12%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNE----KDDKKCIVNDR-NILEAAKQALEYKVADLEAAKT 172
L+ ++ +F+A ++ ++ L + K+D+K + + N++E +A + +++ K
Sbjct: 10345 LQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKA---EPEEIKKEKE 10401
Query: 173 TLNDELERKKDDNNAII---KKALDKRISDLKADAPQRDQE----DDMNALIXXXXXXXX 331
N+E E ++++ I+ +K L + S+L+ + D E +D +I
Sbjct: 10402 KENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKED-- 10459
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
+ ++ I+ +++++E+ + I+ + H KS+
Sbjct: 10460 --------LEKMKSEIMKQRQQMEEERSELDNKIQQ-----------TNLEKHDIEKSKE 10500
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV 691
+ E + E E++ ++ + K + E +K D ++ LV+N + E + ++K V
Sbjct: 10501 IVEKLMVEVEEQ-----RKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKK-V 10554
Query: 692 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
E +T+ + E L+KEK + ++ E + + + + + + + + + D
Sbjct: 10555 DEEIKKERETLREM-EIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDL 10613
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK---------LEASNLTH 1024
L+++ + + E L++R + +A+ + ++ E E ERK +E
Sbjct: 10614 LEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAE 10673
Query: 1025 NDELHKEKDDK-ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE 1201
E+ +EK+++ E M + V+ ER+ L S+++ S +++E ++ DD + E
Sbjct: 10674 LQEIMQEKEEEDEEEMRVI--VEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQE 10731
Query: 1202 RDGLEAVK-------QGLEKRVLDLEATI-------HDIE-------------------M 1282
++ LE +K Q +E+ +L+ I HDIE +
Sbjct: 10732 KEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDI 10791
Query: 1283 KTGKDD---------------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 1417
+ K++ N+A+ Q +RI E++E I K K+ LK++ L
Sbjct: 10792 RLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHL 10847
Query: 1418 SEVTELQEDLNKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 1591
+ E + +E+ ++K+DLEK ++ +K + + RD L +E +
Sbjct: 10848 RKEKEEMRSVIEETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHK 10900
Query: 1592 WVPFEDLVQGFSRKTSPL---DITK 1657
W + + F + S D+TK
Sbjct: 10901 WTQLQQRIDEFDAQVSKQKEEDLTK 10925
Score = 69.3 bits (168), Expect = 7e-09
Identities = 116/533 (21%), Positives = 226/533 (42%), Gaps = 17/533 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ +E KQ +E + +++ ++ +L+++
Sbjct: 4875 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 4934
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++ K + K+ ++ + L+ + ++E D + I N
Sbjct: 4935 QKKMK-----LQKQMFEEEKNKLEQMKIELEREADEISKIKEE-------------TQNK 4976
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
+ + EEL +EK+ L +D + K+ ++E+ ES L + E
Sbjct: 4977 RQRLEKMTEELIREKESLAHLAED---TKTEKKILDEMKVANESSMADL------QREKS 5027
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSAL--VENGEGCEAEKQGLEKTVLERRASNLDT 721
+LE N++ +K + E K K + L ++ + K +EKT +E + +
Sbjct: 5028 ILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIR 5087
Query: 722 MDAIHEEELRKEKVD-----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
EL+K+ D K LTE E + D+E L D L+RD
Sbjct: 5088 EKQNMMTELKKKSEDVEIQMKEILTEK----ELLHNDRKLLTRDVENLQQKLID-LERDS 5142
Query: 887 DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDE-----LHKEK 1048
R+ +++A E ++ EA TD Q + EIE+ KLE + E + KE+
Sbjct: 5143 KRLKLDREAFE---NEKEAMKQMKTDLQIQAD-EIEKIKLETQHDRQRVEEMAAQIQKER 5198
Query: 1049 DDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 1228
D I N ++ + VL K D+E ++ ++ + R L VK+
Sbjct: 5199 D---KINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKE 5255
Query: 1229 GLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDIN 1408
LEK+ E T+ +I+ + + NE + + + I EE ++ D+ +L
Sbjct: 5256 DLEKQ---KENTLAEIQKEREDVEKMNENITREMHE-IKHQEEQMNQKQDELDQL----- 5306
Query: 1409 IWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEKCICGARDGLSTIK 1555
+E+ LQ++L KE K++ + R S+L+K D + T+K
Sbjct: 5307 --KTEIQNLQQELEKEKEIIMKDRSQFDLR----QSELDKQQTNMNDIMETMK 5353
Score = 68.9 bits (167), Expect = 9e-09
Identities = 117/544 (21%), Positives = 231/544 (42%), Gaps = 39/544 (7%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDD--------KKCIVNDRNILEAAKQALEYKVADL 157
Q AD E + EL KD+ +K V+ + + +++ E +L
Sbjct: 1711 QTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIEL 1770
Query: 158 EAAKTTLN---DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 328
E A+ LN ++E +K A +K L K +L+A ++ ED+ AL
Sbjct: 1771 EKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ--RKMMEDEKRALENMKYELQ 1828
Query: 329 XXXXXXXXIVSNLEVNILILH----------EELQKEKDDKTAL-------IKDLVAAEP 457
N+ + EEL+K++ D L IKDL
Sbjct: 1829 RESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDL----E 1884
Query: 458 GKRTVNEI-VSHLESKSRSLKE-HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 631
R +NE+ ++ +++KS L++ L ++ + +E S + I RE +L++ + +
Sbjct: 1885 NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKI----REYDLQQMQTDLN 1940
Query: 632 ALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG-EGCEAE 808
+ E Q ++ V ++ + D I E+ K+ D T+N + + E
Sbjct: 1941 RQ-------QKEMQDIQNAVFMEKSELKKSQDEIAEQ--LKQVGDMMQFTQNEKDNLDRE 1991
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRV-MAEKQALEKRCSDLEAKNASLTDNQEGHEA 985
+ + L +E + L L R+L+ + + +K+ L ++ + + + + D Q+ +
Sbjct: 1992 RAAIIEQKLQMERDMTHL---LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQM 2048
Query: 986 EI--ERKLEASNLTHNDELHKEKDDKESIMNDL--DHVKAERQVLESKVSDMETTYSTLN 1153
+I ER+ E L + +EKD ES++ L D K L K +E L
Sbjct: 2049 KINLEREKEEMQL-QRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK-QKLEDAAVELQ 2106
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 1333
E + M+ E +R+ ++ ++ G+EK+ E T D++ K+ E ++Q ++
Sbjct: 2107 KERDEIMNIAEETKRKREDVDKIRVGIEKQ----EITFKDLKADLQKEAAIVENQRQAVQ 2162
Query: 1334 K---RISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
K + ++E I +L+++I + E+Q +++KE +E + + + TS
Sbjct: 2163 KDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETS 2222
Query: 1505 KLEK 1516
KL +
Sbjct: 2223 KLRE 2226
Score = 68.9 bits (167), Expect = 9e-09
Identities = 104/526 (19%), Positives = 213/526 (40%), Gaps = 32/526 (6%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKC----IVNDRNILEAAKQALEYKVADL------ 157
L+ V D L ++LL E++ K I ++++L KQ + + D+
Sbjct: 3289 LKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQ 3348
Query: 158 ----EAAKTTLNDELERKKDDNNAIIKKALDK--RISDLKADAPQRDQEDDMNALIXXXX 319
E L + R++D+ A K +++ R+ K + + +E +
Sbjct: 3349 LRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKD 3408
Query: 320 XXXXXXXXXXXIVSNLEVNILILHEELQKEK---DDKTALIKDLVAAEPGKRTVNEIVSH 490
I +++I EL KE+ +++T ++ KRT E+
Sbjct: 3409 RANLEKEKSEMIAQKHQMDI-----ELNKERGLIEERTQMLNTYEKEMDQKRTALEV--- 3460
Query: 491 LESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E K + ++EE++++ L+R A ++ +K E+ R E+ + EN
Sbjct: 3461 -EMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLK----EKTRNERQSLEKMAEN-- 3513
Query: 653 GCEAEKQGLEKTVLERRASNLDTMDAIHEE---ELRKEKVDKSALTEN----GEGCEAEK 811
E EK L + + + D M +HE +++KEK + + E+ E ++EK
Sbjct: 3514 -LEKEKDDLAHLAEDTKRKD-DEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEK 3571
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
K ++ E + + + R + +K +E + + KN L
Sbjct: 3572 ----KKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMT--------- 3618
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQK 1171
EL K+ +D E M + V E+++LES ++ L +L
Sbjct: 3619 -------------ELTKQSEDVEIQMKE---VLTEKELLESDRKLLKKDVENLQQKLLII 3662
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 1351
D+E+ +R+ LE K+ L++ DL+ +IE K + + + + +I +
Sbjct: 3663 ESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE-KIKLETQHERQRVEEMTAQIQKD 3721
Query: 1352 EEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
E + + D + + DI ++ + Q++L++ E Q+L++ +
Sbjct: 3722 REYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQEL 3767
Score = 68.6 bits (166), Expect = 1e-08
Identities = 121/564 (21%), Positives = 227/564 (40%), Gaps = 64/564 (11%)
Frame = +2
Query: 17 KVADFEATIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 193
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 12477 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 12534
Query: 194 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 12535 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 12576
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 12577 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 12636
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 721
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 12637 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 12692
Query: 722 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 874
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 12693 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 12750
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKLEA 1009
+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 12751 EESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRERE 12810
Query: 1010 SNLTHNDELHKEKDD----KESIMNDLDHV----------KAERQVLESKVSDMETTYST 1147
D+L KEK+D KE I + +H+ K E + K+ M+T
Sbjct: 12811 EIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQV 12870
Query: 1148 LNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATIHD 1273
N L++ M D + ER+ + A+ K+ ++ +L +++ D
Sbjct: 12871 KTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 12927
Query: 1274 IE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 1444
IE +K + N+ +K LK R ELE I KK K+ ++ E+Q +
Sbjct: 12928 IESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQRE 12977
Query: 1445 LNKESKEKQDLEKRVLELTSKLEK 1516
K +LE++ EL +K+EK
Sbjct: 12978 RKALEKMNAELERKSTELKNKIEK 13001
Score = 65.9 bits (159), Expect = 7e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = +2
Query: 461 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 637
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 638 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 817
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 818 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 998 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 1126
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 1127 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 1303
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 1304 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 1462
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 1463 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 1627
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 1628 RKTSPLDITKT-----CDAVDISEDST 1693
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 1e-07
Identities = 118/608 (19%), Positives = 236/608 (38%), Gaps = 108/608 (17%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKT 172
++ D E + LN+ LN+ K ++ ++ +E K ++ + DL+ +T
Sbjct: 1879 EIKDLE-NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1937
Query: 173 TLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 346
LN + + +D NA+ K L K ++ A Q Q DM
Sbjct: 1938 DLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK--------- 1985
Query: 347 XXIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
NL+ I+ ++LQ E+D L ++L + + K+ V LE SL
Sbjct: 1986 ----DNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRD 2041
Query: 524 FLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKT 688
E+ ++ LER + + + EE K + L E+ E AEKQ LE
Sbjct: 2042 MQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDA 2101
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDK----------------------SALTENGEGC- 799
+E + + M+ E + ++E VDK +A+ EN
Sbjct: 2102 AVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAV 2161
Query: 800 --------------EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 937
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +L
Sbjct: 2162 QKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDEL 2217
Query: 938 EAKNASLTDNQEGHEAEIER----KLEASNLTHNDELHKEKDDKESIMNDLD-------- 1081
E + + L ++++ + E+ + E + N EL E KE + +L+
Sbjct: 2218 EQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRE 2277
Query: 1082 -------------------------HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
++A++ K ++T L+++ + E
Sbjct: 2278 NEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEME 2337
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKK 1336
+ E + +E K+ + ++ E+ + +EM+ Y E ++Q +K
Sbjct: 2338 SLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEK 2397
Query: 1337 RISELEEAISILTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVL 1492
I ++ + I + ++ K++ I V E Q+ + ++SK E ++ K++
Sbjct: 2398 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKIN 2457
Query: 1493 ELTSKLEK 1516
S++EK
Sbjct: 2458 ADLSEVEK 2465
Score = 63.9 bits (154), Expect = 3e-07
Identities = 103/563 (18%), Positives = 240/563 (42%), Gaps = 74/563 (13%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 226
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 10481 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 10540
Query: 227 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIV 358
K +D+ I + + + +++++ ++I +
Sbjct: 10541 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 10600
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 538
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 10601 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 10653
Query: 539 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 700
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 10654 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 10709
Query: 701 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 838
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 10710 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 10764
Query: 839 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1015
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 10765 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 10823
Query: 1016 LTHNDELHKEKDDKESIMNDLDHVKAERQVLES--------KVSDMETTYSTLNNELQQK 1171
+ + K +KE++ H++ E++ + S K D+E + +N + Q
Sbjct: 10824 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 10883
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 1330
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 10884 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 10943
Query: 1331 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 1459
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 10944 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11003
Query: 1460 K----EKQDLEKRVLELTSKLEK 1516
K EK+DLEK E+ + ++
Sbjct: 11004 KMIEQEKEDLEKMKSEIMKQRQQ 11026
Score = 63.9 bits (154), Expect = 3e-07
Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 16/514 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALE-YKVADLEAA------ 166
+EN F IA L ++ K DK+ I N+ L+ +Q E + AD+ +
Sbjct: 13813 IENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKADVTSTEKEMYT 13872
Query: 167 -KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXX 343
K T ELE K+ IK D + D+ + D E + L
Sbjct: 13873 EKVTYKTELEDSKEK----IKPDRDSTLELTDTDSAKTDGEREAQTL-----------ET 13917
Query: 344 XXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
V L + EEL E ++K +I +L A+ + + L+ + RS +E
Sbjct: 13918 KVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAK-------KDLQKLKEECRSAEEE 13970
Query: 524 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLER 700
+ E LER ++L E+++ E + +++ + E Q +E K ++
Sbjct: 13971 --KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQT 14020
Query: 701 RASNLDTMDAIHEEELRKEKVDKSA-LTENGEGCEAEKQGPEKTVLDLEPTIPS-LNDAL 874
R+ + ++ +E ++ + +T+ E + K+ + V LE T+ S + +
Sbjct: 14021 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMR 14080
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
+++ V K ++ LE + + E E +E L+ + + + L + D
Sbjct: 14081 DMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKS-RNEETLLQLLHD 14139
Query: 1055 KESIMNDLDHVKAERQ----VLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAV 1222
K+ + N LD E + + ++ +ETT + + +
Sbjct: 14140 KDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKD--------------------- 14178
Query: 1223 KQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLK 1399
K+ +E +L L+ T + E++ G DD NE E K +ELE+ + + KK +
Sbjct: 14179 KENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELED-----SKEKKKPDR 14233
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
D ++ L++ + D +E++ + + VL+LT
Sbjct: 14234 DSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 14267
Score = 63.5 bits (153), Expect = 4e-07
Identities = 113/537 (21%), Positives = 220/537 (40%), Gaps = 46/537 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL--------- 178
+ E T NDE+ EK I + + +L + LE ADLE K +
Sbjct: 7543 NMEKTYEQQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLA 7599
Query: 179 -NDELERKKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXX 334
N+ LER+K D II+ +A +R ++ A A +RD E+ M +
Sbjct: 7600 ENELLEREKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQE 7658
Query: 335 XXXXXXI--------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH 490
+ + L+ ++L EL+K K D + DL ++T +EI+ H
Sbjct: 7659 ASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKH 7712
Query: 491 ---LESKSRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENG 649
+SK+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 7713 EKDTDSKTRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM---- 7767
Query: 650 EGCEAEKQGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEK 811
K V+ +R D M+ I EE+ +E+ + L N + +
Sbjct: 7768 -----------KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDF 7812
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ + +LE ++ D++R++ E + + +L+ E+
Sbjct: 7813 ELLLERTANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EM 7853
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTL 1150
ER++E S + DE K + + + D+ ++ L ++ ++E + L
Sbjct: 7854 ERRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAEL 7912
Query: 1151 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL 1330
+ Q++ E ER+ LE +K + + D+E +E K++ + Q
Sbjct: 7913 AEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKY 7972
Query: 1331 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 1498
K+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 7973 KEELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8025
Score = 63.5 bits (153), Expect = 4e-07
Identities = 118/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = +2
Query: 2 QALENKVAD-FEATIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 172
Q LE KV D + T T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 14254 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 14313
Query: 173 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 274
+ + LER+++ + + L ++ +K + Q
Sbjct: 14314 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 14373
Query: 275 ----RDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDL 442
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 14374 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 14430
Query: 443 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 619
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 14431 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 14490
Query: 620 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 733
D K+ +EN E E E L++T ER T D
Sbjct: 14491 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 14549
Query: 734 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 910
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 14550 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 14597
Query: 911 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVK 1090
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 14598 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 14638
Query: 1091 AERQVLESKVSDMETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 1249
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 14639 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 14698
Query: 1250 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 1420
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 14699 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 14758
Query: 1421 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 1513
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 14759 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 14800
Score = 61.6 bits (148), Expect = 1e-06
Identities = 89/490 (18%), Positives = 194/490 (39%), Gaps = 3/490 (0%)
Frame = +2
Query: 98 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 277
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 278 DQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 457
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 458 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 637
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 638 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEK 811
+ E E ++ ++ +T R +L+ + ++E L + K L + E +K
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
D ++ + ++ + L++ +DL + + D Q E
Sbjct: 1916 ------------------DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFME- 1956
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAER-QVLESKVSDMETTYSTLNNELQQ 1168
+ +L+ S ++L + D + N+ D++ ER ++E K+ LN EL+
Sbjct: 1957 KSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELES 2016
Query: 1169 KMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISE 1348
+ LNE+ LE + L + + DLE +++ ++ + + ++Q++ + +
Sbjct: 2017 LKLVKKEVLNEKRLLEDCRISLMRDMQDLE----QMKINLEREKEEMQLQRQSIAEEKDK 2072
Query: 1349 LEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICG 1528
LE + L + +KL D ++ + +L KE E ++ + ++K G
Sbjct: 2073 LESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVG 2132
Query: 1529 ARDGLSTIKE 1558
T K+
Sbjct: 2133 IEKQEITFKD 2142
Score = 61.2 bits (147), Expect = 2e-06
Identities = 118/559 (21%), Positives = 227/559 (40%), Gaps = 54/559 (9%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--------- 160
LE A E L+ EL K+ I ++R LE K L+ K D+E
Sbjct: 7144 LEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYE 7203
Query: 161 ----AAKTTLNDELERKKDDNNAIIKKA------LDKRISDLKADAPQRDQEDD---MNA 301
A + + N +++ D+ NA ++K D+ + K + + E + A
Sbjct: 7204 KQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKARAETERVKQGA 7263
Query: 302 LIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIK--DLVAAEPGKRTVN 475
I + ++ N+ E ++K+K + + DL+ A+ K+
Sbjct: 7264 KIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEE 7323
Query: 476 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG 655
+ +ES+ +E + +E LE + + I + L+ E DGK V+N
Sbjct: 7324 MVKQKIESEREIQQEKKKLQRSEEELEDKMQKIK-REMIELKLLQDETDGKRKDVDN--- 7379
Query: 656 CEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL 835
+ + R+ L+ M A E +K +VD+ L + E K ++
Sbjct: 7380 --------KMRQVARKRDELEKMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE 7431
Query: 836 DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL--EAKNASLTDNQEGHEAEIERKLEA 1009
++ + A +R D + EK+ + R L EA+ AS HE E+ + E
Sbjct: 7432 HMQ------SHAEERAGD--LGEKEPVNTRIQRLIQEAEKASKMAWSTKHEPEMRMQREV 7483
Query: 1010 S----NLTHND----------ELHKEKDDKESIMNDLDHVKAERQVLE-------SKVSD 1126
S ++ D E+ ++ + +++ + ER LE + +
Sbjct: 7484 SVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKN 7543
Query: 1127 METTYSTLNNELQ---QKMDDNEAFLN-ERDGLEAVKQGLE--KRVLDLEATIHDIEMKT 1288
ME TY N+E+Q Q+++ ++ L+ ER+ LE + LE K+++ L+ + K
Sbjct: 7544 MEKTYEQQNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALD------KQKL 7597
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILT-DKAKKLLKDINIWLSEVTELQEDLNKESKE 1465
+++ E EK + K I LE T ++A + + E+ + E L+ E +
Sbjct: 7598 LAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQ 7657
Query: 1466 KQDLEKRVLELTSKLEKCI 1522
+ + +++EL +++K I
Sbjct: 7658 EAS-KNQMVELKRQIDKLI 7675
Score = 60.8 bits (146), Expect = 2e-06
Identities = 117/551 (21%), Positives = 209/551 (37%), Gaps = 81/551 (14%)
Frame = +2
Query: 56 DELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK---TTLNDELERKKDD--NN 214
++LL E +K+ ND + E K+ ALE + D+ K +L +E+ K+ + N
Sbjct: 13219 NDLLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNK 13278
Query: 215 AIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
K + DL+ R Q+ +++ I ++LE
Sbjct: 13279 ETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR----------NDLESMK 13328
Query: 380 LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK---EHFLREEEDEV 550
+L EE ++ +D+ P K + LE + +K EH +E E
Sbjct: 13329 TLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKERE--- 13385
Query: 551 LERSASNLAIMKAIRE--------EELRKEKDGKSALVENGEGCEAE----KQGLEKTVL 694
E N I+K+ E E ++E GK A +E+ E A+ ++ V
Sbjct: 13386 -EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 13444
Query: 695 ERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
+ ++ + E EL+ + K+ L E EAEK E + L+ + D
Sbjct: 13445 TEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDI 13504
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL---------------- 1003
+ + +E+ LEK S+L + L + + + E+ER L
Sbjct: 13505 MTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIES 13560
Query: 1004 ----------EASNLTHNDELHKEK----DDKESIMNDLDHVKAER-------QVLESKV 1120
E L E+ E+ DK I + +H++ E+ L+ ++
Sbjct: 13561 EKQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEI 13620
Query: 1121 SDMETTYSTLNNELQQKMDDNEAF-----LNERDGLEAVKQGLEKRVL-----------D 1252
+ LN E++ K + E + D L+ L + ++
Sbjct: 13621 KRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQ 13680
Query: 1253 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 1432
L+ T D E +T D+ +T ++R LEE ++ T K ++K + SEV E
Sbjct: 13681 LKTTSRDAETQTSLDE-----ITKTDERRQRALEETVA-TTAKQPIVIKLEDTLTSEVQE 13734
Query: 1433 LQEDLNKESKE 1465
+++ LN E KE
Sbjct: 13735 MRDHLNNEIKE 13745
Score = 60.5 bits (145), Expect = 3e-06
Identities = 112/543 (20%), Positives = 217/543 (39%), Gaps = 48/543 (8%)
Frame = +2
Query: 14 NKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN-DEL 190
+K+ + +A + EL K D K ++D LE + + D ++ L E+
Sbjct: 7672 DKLIELKADLLQQQTELKKTKADLKQQMDD---LEKTRSEILKHEKDTDSKTRELELIEI 7728
Query: 191 ERKKDDNNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXXIV 358
+R+KDD I+K L+KR + L+++ ++D + M +I
Sbjct: 7729 QRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANAT 7788
Query: 359 SNLE---VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSR 508
+ + IL +Q + D +TA ++D +A +R V E+V + R
Sbjct: 7789 EEINRERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVR 7847
Query: 509 SLK---EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQG 676
+LK E + + + E+ E+ I + I++ ++R+ G +E + E +
Sbjct: 7848 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 7907
Query: 677 LEKTVLERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT 829
+ + E++ + +H+E E+ +EK D E E +++ E T
Sbjct: 7908 MRAELAEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFT 7967
Query: 830 -VLDLEPTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
+ + + S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +
Sbjct: 7968 DIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-K 8026
Query: 998 KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 1177
K E DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8027 KGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDL 8086
Query: 1178 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------ 1339
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8087 FRSELQRQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKI 8143
Query: 1340 ----------ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
I + + IL D + +D + E +L E D+E+ V
Sbjct: 8144 RFDIANARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLV 8199
Query: 1490 LEL 1498
LE+
Sbjct: 8200 LEV 8202
>ref|XP_005159742.1| PREDICTED: titin isoform X5 [Danio rerio]
Length = 15134
Score = 101 bits (251), Expect = 2e-18
Identities = 132/600 (22%), Positives = 266/600 (44%), Gaps = 39/600 (6%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRN--------ILEAAKQALEYKVADL 157
Q +E A + +N+ L+ E + K ++N++N +++ K LE + DL
Sbjct: 5602 QRVEEMTAQIQKDRDKINN-LIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDL 5660
Query: 158 EAAKTTL---NDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXX 316
E ++ L ++LE++K++ A I+K L+K ++ + + + QE+ MN
Sbjct: 5661 EKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQ----- 5715
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKRTVNEIV 484
+ L+ I L +EL+KEK+ ++ L + + + +N+I+
Sbjct: 5716 ---------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIM 5766
Query: 485 SHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
++++ + L K+ EE+ + +E+ N+ + +E+L+ K K + E E
Sbjct: 5767 ETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLE 5826
Query: 662 AEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTENGEGCEAEKQGPEK 826
K LE+ + R +T + EEL+KE+ D + L E+ + EK ++
Sbjct: 5827 QMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED---TKREKNSLDE 5883
Query: 827 TVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLE 1006
+ E ++ L Q++ + K+ + K+ D+E + D E E+E+ L+
Sbjct: 5884 MKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DKIRLREDELEQ-LQ 5934
Query: 1007 ASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
A E+HK++ + E + +++ ER + V D+++ +L+ + + D E
Sbjct: 5935 A-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE 5984
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI 1342
AF NE++ L+ +K LE+ ++E T H+ EM + N KQ K ++
Sbjct: 5985 AFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKV 6044
Query: 1343 ------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
E+E+ + K L +D+ + ++ L+E+ NK + K LE+ E+ S
Sbjct: 6045 MIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-S 6103
Query: 1505 KLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 1684
K+++ R L + A + E L + RK LD K + +++
Sbjct: 6104 KIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVLDKIKVANESTLAD 6154
Score = 99.8 bits (247), Expect = 5e-18
Identities = 131/591 (22%), Positives = 260/591 (43%), Gaps = 87/591 (14%)
Frame = +2
Query: 5 ALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTT--- 175
A+ V D + + +L+ +L + K D++ N+R +L+ K L+ K ++E K
Sbjct: 4253 AIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQH 4312
Query: 176 -------LNDELERKKDDNNAIIKKA--LDKRISDLKADAPQRDQ--EDDMNALIXXXXX 322
+ ++++++D N +I++ D ++++K + ++ + E D + L
Sbjct: 4313 DRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHD 4372
Query: 323 XXXXXXXXXXIVSNLEVNILILHEELQKEKDDK-------TALIKDLVAAEPGKRTVNEI 481
NLE I E+QKE++D T I D+ E + +
Sbjct: 4373 LEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDE 4432
Query: 482 VSHLESKSRSLKEHFLREEEDEVLERSASNLA-------------IMKAIREEELRKEKD 622
+ L+++ ++L++ +E+E + +RS +L IM+ ++ E + +KD
Sbjct: 4433 LDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKD 4492
Query: 623 GKSALVENGEGCEAEKQG----------------LEKTVLERRASNLDTMDAIHEEELRK 754
K E + E EK L+K VLE S L+ M EL +
Sbjct: 4493 -KEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKI----ELER 4547
Query: 755 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 934
E V+ + E + E+Q EK L+ L + +++ + K A E +D
Sbjct: 4548 EAVEIRKIKEE---IQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLAD 4604
Query: 935 LEAKNASLTDNQEG---HEAEIERKLEASNLTHND------ELHKEKDDKESIMNDLDHV 1087
+ + ++L + +E ++E K E L ++ E+HK++ + E + ++
Sbjct: 4605 ILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEK---EKINI 4661
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE--- 1258
++ER + V D++ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 4662 ESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIK 4721
Query: 1259 -ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AK 1387
T HD +++ +D+ N E+ L ++ ++EE I SI +DK +
Sbjct: 4722 LETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLE 4781
Query: 1388 KLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 1516
K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 4782 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 4832
Score = 99.4 bits (246), Expect = 6e-18
Identities = 124/547 (22%), Positives = 230/547 (42%), Gaps = 48/547 (8%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 217
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 4152 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 4211
Query: 218 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEE 397
K+ R+ + + + Q + + V +L+ + L +
Sbjct: 4212 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 4271
Query: 398 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 553
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 4272 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 4324
Query: 554 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 706
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 4325 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 4384
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 865
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 4385 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 4444
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 4445 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 4504
Query: 1040 KEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
KEK D ++S+ DL +K ++QVLE + S +E L E + E NER
Sbjct: 4505 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 4564
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 1369
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 4565 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 4621
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 1525
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 4622 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 4681
Query: 1526 GARDGLS 1546
RD S
Sbjct: 4682 LDRDAES 4688
Score = 94.0 bits (232), Expect = 2e-16
Identities = 133/541 (24%), Positives = 243/541 (44%), Gaps = 54/541 (9%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 5212 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 5271
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5272 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5310
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5311 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5368
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 718
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 5369 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 5428
Query: 719 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 883
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 5429 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 5477
Query: 884 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1057
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 5478 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINI 5534
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
ES ER + V D++ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 5535 ES----------ERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 5584
Query: 1238 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 1363
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 5585 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 5644
Query: 1364 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 1513
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 5645 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 5704
Query: 1514 K 1516
+
Sbjct: 5705 E 5705
Score = 91.3 bits (225), Expect = 2e-15
Identities = 102/535 (19%), Positives = 239/535 (44%), Gaps = 32/535 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 4461 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4520
Query: 188 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXXI 355
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 4521 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 4580
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 529
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 4581 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 4640
Query: 530 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 667
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 4641 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 4699
Query: 668 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
K+ L+ KT LER A ++ + E + +++V++ A + E E D+
Sbjct: 4700 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 4757
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLT 1021
+ N ++ + + ++K LEK DLE + L +E E + E L
Sbjct: 4758 --VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA----- 4810
Query: 1022 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
E+ KE++D E+I ++ +K + + + K +++ + + N Q+ + E
Sbjct: 4811 ---EIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 4867
Query: 1190 FLNERDGLEAVKQGLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEA 1360
+ +R L+ + L+K+ + D+ T+ + + KD + E +KQ ++K ++++
Sbjct: 4868 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 4927
Query: 1361 ISILTDKAKKLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
L + KK+ ++ E +L++ +L +E+ E +++ +LEK
Sbjct: 4928 RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 4982
Score = 90.1 bits (222), Expect = 4e-15
Identities = 127/548 (23%), Positives = 237/548 (43%), Gaps = 49/548 (8%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 166
+ LE+ + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3639 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3698
Query: 167 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 313
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3699 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3752
Query: 314 XXXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 475
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3753 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3796
Query: 476 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3797 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3851
Query: 653 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 808
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3852 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3905
Query: 809 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 979
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3906 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQ 3965
Query: 980 -EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 1156
+AEI ++ E+ KEK + ES ER + V D++ +L+
Sbjct: 3966 LQAEIHKQQR--------EIEKEKSNIES----------ERAAIIKIVEDLQHKIISLDR 4007
Query: 1157 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIEMKTGKDDDYNEA--- 1315
+ + D EAF NER+ L+ +K LE+ ++E T H+ + D+ E
Sbjct: 4008 DAESLKLDREAFENEREVLKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNN 4067
Query: 1316 -------EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQD 1474
K+ ++++ E+E+ + K L K++ + + ++E+ NK + K +
Sbjct: 4068 ERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIE 4127
Query: 1475 LEKRVLEL 1498
LEK E+
Sbjct: 4128 LEKEADEI 4135
Score = 89.4 bits (220), Expect = 6e-15
Identities = 114/525 (21%), Positives = 236/525 (44%), Gaps = 44/525 (8%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE K LE YKV DLE K E++++
Sbjct: 4756 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKE 4815
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 4816 REDLEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 4854
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 4855 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 4912
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT------VLER 700
+ + +E+ N+ + +E+ +K K K E E K LE+ + E
Sbjct: 4913 QKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEE 4972
Query: 701 RASNLDTMDAIHEEELRKE----------KVDKSALTEN---GEGCEAEKQGPEKTVLDL 841
+ ++ + EE +R++ K +K L E E A+ Q + + ++
Sbjct: 4973 TQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEM 5032
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNL 1018
I L + + + ++ + L+K ++++ + + + + E+E + E N+
Sbjct: 5033 RENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNM 5092
Query: 1019 THNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
EL K+ +D E I+ + + + +R++L V +++ L + ++ D E
Sbjct: 5093 M--TELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 5150
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS 1366
AF NE++ ++ +K L+ + ++E I+++T D E ++K ++ I
Sbjct: 5151 AFENEKEAMKQMKTDLQIQADEIE----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE 5206
Query: 1367 ILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLEL 1498
T++ +L + N + E + +Q D + KE+ +LEK EL
Sbjct: 5207 -ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSEL 5250
Score = 87.8 bits (216), Expect = 2e-14
Identities = 122/538 (22%), Positives = 233/538 (43%), Gaps = 24/538 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E++ E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 182 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 340
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 520
I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 521 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 682
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 683 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 832
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1009
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1010 SNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
++++ +++L KE+ ++E I N +K E LE ++ NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 1190 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 1369
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 1543
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 85.9 bits (211), Expect = 7e-14
Identities = 116/534 (21%), Positives = 238/534 (44%), Gaps = 34/534 (6%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLND 184
K+ + + +A L+ EL KD+ + I +R+ +E + L ++ +E + D
Sbjct: 9116 KMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQD 9175
Query: 185 ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSN 364
+ ++ +I +K + +I + + Q +QE N L I N
Sbjct: 9176 KQNHLEEKELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELN 9232
Query: 365 LEVN------ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK 502
+ N + + EL+ EK D K + L E K + ++ L+SK
Sbjct: 9233 KQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSK 9292
Query: 503 -SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
++ KE + ++R + + + + + + K+ L E E + E++ L
Sbjct: 9293 REQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKL 9352
Query: 680 E--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E K +++ A NL+ + + + K ++ ++ L E CE ++ E+ D+E I
Sbjct: 9353 EEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQI 9412
Query: 854 PSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EAS 1012
+ +A L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +
Sbjct: 9413 QNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKA 9472
Query: 1013 N--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL---QQKMD 1177
N L D+L KEK+D N LD ++ E Q + +++ NE+ QQ+++
Sbjct: 9473 NEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLE 9532
Query: 1178 DNEAFLNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 1354
++ +NE G LE ++ EK+ +E + +M E++ L + SELE
Sbjct: 9533 ESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELE 9581
Query: 1355 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ + + + KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 9582 KDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 9635
Score = 85.5 bits (210), Expect = 9e-14
Identities = 103/492 (20%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = +2
Query: 71 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 238
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 239 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDD 418
+R+++++ + +++ D+ ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 419 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 598
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 599 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 778
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 779 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 958
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 959 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETT 1138
+ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 1309
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 1310 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 1453
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1454 --ESKEKQDLEK 1483
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 82.4 bits (202), Expect = 7e-13
Identities = 111/556 (19%), Positives = 242/556 (43%), Gaps = 54/556 (9%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL----------- 157
EN + E + +++ N ++ K + +R ++ KQ L+ + DL
Sbjct: 9395 ENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENV 9454
Query: 158 EAAKTTLNDELERKKDDNNAIIKKA--LDKRISDL-----KADAPQRDQEDDMNALIXXX 316
E +K +L++E + + N I+++ L+K D+ K D Q + +++ A+
Sbjct: 9455 EMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIK 9514
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEE------LQKEKDDKTALIKDL-VAAEPGKRTVN 475
LE ++ ++EE ++ + + + I+++ V A+ ++ ++
Sbjct: 9515 YELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELD 9574
Query: 476 EIVSHLESKSRSLKEHFLREEEDE-VLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I S LE + + + D ++E+ ++L MK+ + ++ +D +S L + +
Sbjct: 9575 QIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIK 9634
Query: 653 GCEAEKQGLEKT--VLERRASNLDTMD---AIHEEELRKEK---VDKSALTENGEGCEAE 808
EK +EK ++ER + ++ + +EEL E+ VD+ L CE E
Sbjct: 9635 EANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQ---CETE 9691
Query: 809 KQGPEKTVLDLEPTIPSLNDAL-------QRD-------LDRVMAEKQALEKRCSDLEAK 946
Q + + ++E + + + L QRD ++ +K+ LEK + + +
Sbjct: 9692 LQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQ 9751
Query: 947 NASLT---DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLES- 1114
L D E EI K ++ + + KE + + ++ ER+ LE
Sbjct: 9752 KQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEV 9811
Query: 1115 --KVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKT 1288
K+ +M+T ++E+ QK+++ L+ +++ + K EA ++M
Sbjct: 9812 NGKIIEMKTKAELEHHEINQKIEE----------LQTLQEQIMKEKEKAEAMTIKLKM-- 9859
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEK 1468
E++ L + SEL + + + KKL DI + E +L++ ++ +K
Sbjct: 9860 ---------EREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 9910
Query: 1469 QDLEKRVLELTSKLEK 1516
Q++EK EL +K+++
Sbjct: 9911 QEMEKERSELDNKIQQ 9926
Score = 82.0 bits (201), Expect = 1e-12
Identities = 117/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N ++ E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 8800 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 8859
Query: 188 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 343
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 8860 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 8918
Query: 344 XXXIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 514
L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 8919 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 8973
Query: 515 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 8974 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9033
Query: 680 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9034 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9092
Query: 854 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1030
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9093 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 9147
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 1210
E H+ + + + + + ++ + Q+++ K + +E ++ + ++ N F E++
Sbjct: 9148 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 9207
Query: 1211 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 1390
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 9208 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 9253
Query: 1391 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 1516
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 9254 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 9295
Score = 81.3 bits (199), Expect = 2e-12
Identities = 121/518 (23%), Positives = 225/518 (43%), Gaps = 20/518 (3%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + E +L+ +DDK + NDR+ E LE K
Sbjct: 8607 QDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELK-----------R 8655
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+EL R+ +D + +K L +R D + +RD E+ AL
Sbjct: 8656 EELVRETED---LERKILQQREQD---EMAKRDIENQTEAL------------------E 8691
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
++V+IL E KE ++ V +E K + + L+S+ L+ EE+
Sbjct: 8692 VMKVDILKKRNEFAKEMEN--------VHSERQKLLL--LQGALQSQESELENRVFMEEQ 8741
Query: 542 DEVLERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
+ + A K + E E + E++ L+E + E E+ + K +E+ +L
Sbjct: 8742 KHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR-EKEQLEISKNQIEQEKKDL 8800
Query: 716 DTMDAIHE---EELRKEKV----DKSALTENGEGCEAEKQGPEKTVLDLE---PTIPSLN 865
M + E E LR EK +K+AL + + + K DLE I
Sbjct: 8801 QNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEK 8860
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
++ + R+ ++ ++K S+L+ ++ +E ++E +++ +E+
Sbjct: 8861 KRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIE 8920
Query: 1040 KEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 1219
KE + DL++ KAE Q E K D+ ++ ++Q+K + + L++ +
Sbjct: 8921 KESQRLQDATIDLENAKAEIQRQEDKFEDI------IDIKIQEKEREIKIQLDKE--TKR 8972
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKK 1390
+ + +E +V DLE + D++ + + +D E EKQ LK+ ELE+ + LT + ++
Sbjct: 8973 LSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQE 9032
Query: 1391 LLKDINIWLSEVTELQEDLNKES---KEKQDLEKRVLE 1495
++ N ++ +L EDL KE+ KEK LEK +E
Sbjct: 9033 TEEERNNLMALKNQL-EDLRKENEIVKEKLTLEKSNIE 9069
Score = 80.9 bits (198), Expect = 2e-12
Identities = 111/536 (20%), Positives = 231/536 (43%), Gaps = 46/536 (8%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 11493 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 11552
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 11553 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 11612
Query: 362 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 11613 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 11672
Query: 509 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 664
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 11673 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 11727
Query: 665 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 811
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 11728 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 11787
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 11788 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 11847
Query: 992 --ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 11848 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 11907
Query: 1154 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 1318
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 11908 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 11963
Query: 1319 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 1480
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 11964 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12016
Score = 80.1 bits (196), Expect = 4e-12
Identities = 94/521 (18%), Positives = 225/521 (43%), Gaps = 46/521 (8%)
Frame = +2
Query: 92 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 244
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 11161 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 11220
Query: 245 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEEL 400
I ++K ++++E+ M A + I S LE + E
Sbjct: 11221 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 11274
Query: 401 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 580
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 11275 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 11333
Query: 581 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 706
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 11334 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11393
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 11394 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 11449
Query: 887 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1033
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 11450 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 11509
Query: 1034 LHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGL 1213
+ KEK+ +E V+ ER+ +E S +E S +++E ++ DD + E++ L
Sbjct: 11510 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 11569
Query: 1214 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 1393
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 11570 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 11628
Query: 1394 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 11629 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 11669
Score = 79.3 bits (194), Expect = 6e-12
Identities = 122/575 (21%), Positives = 250/575 (43%), Gaps = 74/575 (12%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K+ E T +++ EK+ ++ V R +E K+ L+ + LE ++ ++ E
Sbjct: 10938 ETKIKIIEMKTKTEPEKIKKEKEKEEEEVM-RAKVEMKKEELDQIKSQLERVRSEIDHEQ 10996
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 10997 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQ 11056
Query: 362 NLEV-------NILILHEEL----QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V +I + EEL QK D++ ++++ + + E+ ++ +
Sbjct: 11057 KLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKE 11116
Query: 509 SLKE---HFLREEED-------------EVLERSASNLA-----------IMKAIREE-- 601
+LKE H +E+E+ E LE+ ++++ ++K REE
Sbjct: 11117 TLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEIN 11176
Query: 602 ----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE--KV 763
+L++ D A V + + KQ K + E R S +T I E + + E K+
Sbjct: 11177 HKWTQLQQRIDEFDAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKI 11233
Query: 764 DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEA 943
K E E A+ + ++ + ++ + + + + ++ +K+ +E+ DLE
Sbjct: 11234 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11293
Query: 944 KNASLTDNQEGHE---AEIERKLEASNLTHND-ELHKE---------KDDKESIMNDLDH 1084
+ + ++ E +E+E K+ + + D E KE ++ K I +
Sbjct: 11294 MKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEE 11353
Query: 1085 VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEAT 1264
+ ERQ + + + S L NE ++ + NE ER+ L+ ++ LEK ++++
Sbjct: 11354 LDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI 11413
Query: 1265 IHDIEMKTGKDD-----DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVT 1429
E + K+D + +KQ L+ + LE+ + K K+L + I+ + ++V+
Sbjct: 11414 TE--ETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 11471
Query: 1430 -ELQEDLNKESKEKQD------LEKRVLELTSKLE 1513
+ +EDL KE + K+D + +LE+ +K E
Sbjct: 11472 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAE 11506
Score = 78.6 bits (192), Expect = 1e-11
Identities = 115/572 (20%), Positives = 245/572 (42%), Gaps = 91/572 (15%)
Frame = +2
Query: 56 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 193
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 5858 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 5917
Query: 194 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 331
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 5918 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 5977
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 499
N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 5978 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6034
Query: 500 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 676
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6035 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6094
Query: 677 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 808
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6095 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 6154
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 988
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 6155 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 6214
Query: 989 IERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
+ E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 6215 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 6272
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 1294
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6273 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 6332
Query: 1295 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 1420
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 6333 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 6388
Query: 1421 EVTELQEDLNKESKE------KQDLEKRVLEL 1498
E+ + + L K SKE K + EK+ ++L
Sbjct: 6389 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 6420
Score = 77.8 bits (190), Expect = 2e-11
Identities = 108/524 (20%), Positives = 230/524 (43%), Gaps = 31/524 (5%)
Frame = +2
Query: 38 TIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL---NDELERKKDD 208
T+ + L EK++ K I + K+ LE D++ L D LE++K+D
Sbjct: 10003 TLKEMEAHLEKEKEEMKSITEETR---RQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKED 10059
Query: 209 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILIL 388
N + L +RI + A ++ +ED I + + +
Sbjct: 10060 INHEWTQ-LQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDI 10118
Query: 389 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE--VLERS 562
+E +KE++++ +K E + ++ I S L+ + RS +H ++ D+ ++E+
Sbjct: 10119 KKEKEKEEEEEEMRVK----VEMDGKELDRIKSELK-RERSEIDHEQKKLNDDKKIIEQE 10173
Query: 563 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE 742
NL MK+ ++ ++ ++ +S L + EK +E + + ++ + HE
Sbjct: 10174 KQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEI 10233
Query: 743 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 922
+ +KE++D E+Q + D + + LQ + +R+ + ++K
Sbjct: 10234 QFQKEELD------------IERQ----KIADEQDLLIQNKSELQNENERIRNLNEIIKK 10277
Query: 923 RCSDLEAKNASLTDNQEGHEAEIE--RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAE 1096
L+ A L +E ++ E R+L+ + +++K+ D +MN D ++ E
Sbjct: 10278 ERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKD---LMNQRDLLEQE 10334
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IH 1270
R+ + K +LQQ++D+ +A ++++ + K+ G+++ LE T +
Sbjct: 10335 REEINHKWK-----------QLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 10383
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL------------------ 1396
IEMKT + + + EK+ + E EE I ++ + +K L
Sbjct: 10384 VIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQ 10443
Query: 1397 KDINIWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEK 1516
K +N ++ + + +EDL K K++Q +E+ EL +K+++
Sbjct: 10444 KKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQ 10487
Score = 76.6 bits (187), Expect = 4e-11
Identities = 112/520 (21%), Positives = 215/520 (41%), Gaps = 22/520 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA------- 166
+EN F+ IA L + K DK+ I N+ L+ +Q E + + +
Sbjct: 14154 IENITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYD 14213
Query: 167 -----KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 331
KT L D E+KK D ++ +K ++D AD+ + D E + L
Sbjct: 14214 EKVTYKTELEDSKEKKKPDRDSSLK------LTD--ADSAKTDGEREAQTL--------- 14256
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
V L EEL E ++K +I +L A+ + + L+ + RS
Sbjct: 14257 --ETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAK-------KDLQKLKEECRS 14307
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KT 688
+E + E LER ++L E+++ E + +++ + E Q +E K
Sbjct: 14308 AEEE--KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKM 14357
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPS--- 859
++ R+ + ++ ++ +T+ E + K+ + TV LE T+ S
Sbjct: 14358 QIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQ 14417
Query: 860 -LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDEL 1036
+ D+L ++++ V K ++ LE + + E E +E +E + + ++L
Sbjct: 14418 EMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKL 14476
Query: 1037 HKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER 1204
+ DKE + N LD ++ + K++ +ETT + +
Sbjct: 14477 LQLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETTIVLMKKD--------------- 14521
Query: 1205 DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDK 1381
K+ +E +L L+ T + E++ G DD NE EK K +ELE+ +
Sbjct: 14522 ------KENIENELLQLKQTEQEREIQRGTDDTSNEREKYDEKVTYKTELED-----NKE 14570
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
KK +D ++ L++ + D +E++ + + VL+LT
Sbjct: 14571 KKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 14610
Score = 76.3 bits (186), Expect = 5e-11
Identities = 125/547 (22%), Positives = 241/547 (44%), Gaps = 47/547 (8%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT---TLNDE 187
K+AD + + EL NE + I N I++ ++ L+ A LE K ++++E
Sbjct: 10246 KIADEQDLLIQNKSELQNENER---IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEE 10302
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R K+D L+K +D+ +D + + L +
Sbjct: 10303 TRRLKED--------LEKMSTDVNKQ--NKDLMNQRDLLEQEREEINHKWKQLQQRIDEF 10352
Query: 368 EVNILILHEE-LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES---KSRSLKEHFLRE 535
+ + E+ L KEK K +D + E K V E+ + E K KE+ E
Sbjct: 10353 DAQVSKQKEQDLPKEKGMK----EDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEE 10408
Query: 536 EEDE----VLERSASNLAIMKAIREEELRKEKDGKSA-LVENGEGCEAEKQGLEKTV--- 691
EE+E ++E L +K+ E +R E D + L + + E EK+ LEK
Sbjct: 10409 EEEEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEI 10467
Query: 692 ------LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDL 841
+E S LD + I + L K ++KS E E+Q + K LD+
Sbjct: 10468 MKQRQQMEEERSELD--NKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDI 10525
Query: 842 E-PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNL 1018
E I + L ++ ++ E + ++K +++ + +L E EI K E L
Sbjct: 10526 ERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETL------REMEIHLKKEKEEL 10579
Query: 1019 THN-DELHKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 1183
+E + K+D E + D++ H+K +R +LE + ++ + +LQQ++D+
Sbjct: 10580 RSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT----QLQQRIDEF 10635
Query: 1184 EAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDIEMKTGKDDDYN-----EA 1315
+A +++ + +E ++ LE+ R+++++ A + +I + ++D+ E
Sbjct: 10636 DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVEM 10695
Query: 1316 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 1495
E++ L + SEL+ S + + KKL D I E +L++ ++ ++Q +E+ E
Sbjct: 10696 EREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSE 10755
Query: 1496 LTSKLEK 1516
L +K+++
Sbjct: 10756 LDNKIKQ 10762
Score = 75.9 bits (185), Expect = 7e-11
Identities = 111/513 (21%), Positives = 213/513 (41%), Gaps = 67/513 (13%)
Frame = +2
Query: 179 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXI 355
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 535
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 536 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 682
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 683 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 805
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 806 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 928
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 929 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAE 1096
DL+ + A + +E E+E+ + N D E K E D K ++ + ++++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 1276
R+++E + +E L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 1277 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 1417
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 1418 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 75.5 bits (184), Expect = 9e-11
Identities = 110/522 (21%), Positives = 225/522 (43%), Gaps = 35/522 (6%)
Frame = +2
Query: 5 ALENKVADFE---ATIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEA 163
A + + DFE I N EL ++++ K + + R LE + + +V +
Sbjct: 6599 AFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITN 6658
Query: 164 AKTTLND---ELERKKDD-----------NNAIIKKA--LDKRISDLKADAPQRDQEDDM 295
+L+ EL + ++D N I+ + LD+R SD+ D Q++ +D M
Sbjct: 6659 ENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQKEVDDLM 6716
Query: 296 NALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVN 475
+ ++N+E L + + + K D +L + A E + +N
Sbjct: 6717 D--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLN 6762
Query: 476 EIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E +E + L ++ ++D++ ++R NL + K + E ++ + K +L
Sbjct: 6763 EEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAI 6822
Query: 653 GCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ 814
G + +EK E+ ++E A+ LD + E + +E++D++ +
Sbjct: 6823 GFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLF 6882
Query: 815 GPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 994
EKT DL+ T +N D + + ++ L K E E
Sbjct: 6883 QEEKT--DLQKTKEEIN----YDREEIYRQRTELNK-------------------EKETL 6917
Query: 995 RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKM 1174
+++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + + E +
Sbjct: 6918 KQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELA 6974
Query: 1175 DDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ---TLKKRIS 1345
D E NE+D L+ ++ ++K + +L+ E + + N+ +Q +K +
Sbjct: 6975 RDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTEEIKLKND 7028
Query: 1346 ELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 1465
L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7029 SLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7070
Score = 75.5 bits (184), Expect = 9e-11
Identities = 105/540 (19%), Positives = 219/540 (40%), Gaps = 57/540 (10%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 12812 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 12861
Query: 221 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEV 373
+ AL+K + DL+ + +++NAL+ E
Sbjct: 12862 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 12902
Query: 374 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 532
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 12903 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 12961
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 12962 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13015
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 892
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13016 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13075
Query: 893 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1042
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13076 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13134
Query: 1043 EKDDKESIMNDL----------------------------DHVKAERQVLESKVSDMETT 1138
EKD E I DL D + + + L S +D+E
Sbjct: 13135 EKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQ 13194
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 13195 AKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDLT 13236
Query: 1319 KQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL ++
Sbjct: 13237 LQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQL 13296
Score = 74.3 bits (181), Expect = 2e-10
Identities = 122/611 (19%), Positives = 247/611 (40%), Gaps = 64/611 (10%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELER 196
+V + L E+ ++ K ++++ I ++ Q L + + L E+E
Sbjct: 8201 EVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIEN 8260
Query: 197 KKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVN 376
K D K L+K ++L + Q+++E L ++E++
Sbjct: 8261 TKRD-----KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEIS 8313
Query: 377 ILILHEEL-----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES-------- 499
++ E+ QK K++ + ++L+ + +N V HL
Sbjct: 8314 RELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQ 8373
Query: 500 --KSRSLKEHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDG 625
K ++ EH E + +++LE+ L +++I E L+K +D
Sbjct: 8374 YIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED- 8432
Query: 626 KSALVENGEGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGE 793
+ + E EKQ E + L+R+ +++ I E++ K K+D E
Sbjct: 8433 ---MEKEKENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSA 8488
Query: 794 GCEAEKQGPEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEA 943
E E + E DLE SLNDA LQ+ + + EK+ +E+ ++
Sbjct: 8489 AFEKEHKRLENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKT 8548
Query: 944 KNASLTDNQE-----------GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD-HV 1087
+ + +E GHE ++++K E + D+L ++ + + + DL +
Sbjct: 8549 ERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKL 8602
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 1267
+ +RQ +E ++MET +L+ ++ DD N+RD E LE + +L
Sbjct: 8603 QMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRET 8662
Query: 1268 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 1447
D+E K + + +E K+ ++ + LE + K + K++ SE +L
Sbjct: 8663 EDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQ 8722
Query: 1448 NKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGF 1624
++ +LE RV +E L++ + + E MS+ + + + L++
Sbjct: 8723 GALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEEL 8779
Query: 1625 SRKTSPLDITK 1657
R+ L+I+K
Sbjct: 8780 QREKEQLEISK 8790
Score = 73.6 bits (179), Expect = 3e-10
Identities = 109/526 (20%), Positives = 232/526 (44%), Gaps = 23/526 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N+ D E + + DE N + K+ + +DR+ LE + DLE KT + +
Sbjct: 3046 LQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKER-------FDLEKTKTEMGN- 3097
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
+KK L+ +I + + +E + I+ L
Sbjct: 3098 -----------LKKQLESQIRQHEIQLVEIQKERE--------------------ILEQL 3126
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKSRSLKEHFLREEED 544
++N+ E+L+KE+D D+ +E K ++ E + + ++ +++E D
Sbjct: 3127 KINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTR--------IKQEMD 3178
Query: 545 EVLERSASNLA-------IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 703
E LE++ NLA + K I E+E K + K+ L + E + E Q E+ LE
Sbjct: 3179 E-LEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQN-ERQNLEEA 3236
Query: 704 ASNL----DTMDAIHEEELRKEKVDKSALTE---NGEGCEAEKQGPEKTVLDLEPTIPSL 862
+ L + ++++ EE RK+ V ++ E + E+ KQ E+ +++L+ T+ +
Sbjct: 3237 GTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTVTDI 3296
Query: 863 NDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHK 1042
A + ++++ E++ + + ++++A+ L ++G E++++ N T L +
Sbjct: 3297 AGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGIS---EQQVDIVNKTEQLRLRE 3353
Query: 1043 EKDD--KESIMNDLDHVKAERQVL---ESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
+ + + I D ++A R+ + + ++ +T L E+ Q M+ +D
Sbjct: 3354 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMME-----YASKD 3408
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAK 1387
+ LEK ++ A H ++++ K+ E Q L E+++ + L + K
Sbjct: 3409 -----RANLEKEKSEMIAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMK 3463
Query: 1388 KLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
+L E +LQ+ +L +E+ + + L+++ LEK
Sbjct: 3464 ELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEK 3509
Score = 72.8 bits (177), Expect = 6e-10
Identities = 117/569 (20%), Positives = 233/569 (40%), Gaps = 66/569 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAK 169
Q+ + + + + T+ L DE +++ + N+ ++ K +LE ADL+
Sbjct: 13091 QSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRKA 13150
Query: 170 TTLNDELERKKDDNNAIIKKAL--------DKRISDLKADAPQRDQ--EDDMNALIXXXX 319
L++E+ + + I + A ++ + ++AD ++ + E D+ L
Sbjct: 13151 EKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKE 13210
Query: 320 XXXXXXXXXXXIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 487
+ +LE N L L +EL+KEK +I D+ + + V+
Sbjct: 13211 ILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------DAVA 13262
Query: 488 HLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 13263 SLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR 13321
Query: 662 AEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTENGE 793
+ + ++ + E R D + DA+ + +EL K D E+ E
Sbjct: 13322 NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVE 13381
Query: 794 GCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA------- 943
E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 13382 KEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKT 13441
Query: 944 -----KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH--- 1084
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 13442 LVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEV 13501
Query: 1085 ------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGLEKR 1243
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +E
Sbjct: 13502 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE-- 13559
Query: 1244 VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 1423
+EKQ++++ +EL K+L +++ + E
Sbjct: 13560 -----------------------SEKQSIERERAEL-----------KRLKEEVEVQ-HE 13584
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKL 1510
T LQ+D N KEK+ LE T ++
Sbjct: 13585 RTLLQQDKNMIQKEKEHLEGEKARTTEEI 13613
Score = 72.4 bits (176), Expect = 8e-10
Identities = 108/548 (19%), Positives = 231/548 (42%), Gaps = 46/548 (8%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ K ++ + +ND + K+++K + D+ +E K+ +E + D + + +L+++
Sbjct: 3781 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 188 LERKK-------DDNNAI--IKKALDKRISDLKADAPQRDQE--------DDMNALIXXX 316
L+ K ++ N + +K L++ +++ + E +++
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLE 496
I+ ++V L ELQKEK + + +++ + E + E
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3960
Query: 497 SKSRSLKEHFLREEEDEVLERS------ASNLAIMKAIREEELRKEKDGKSALVENGEGC 658
+ L+ +++ + E+S A+ + I++ ++ + + ++D +S ++ E
Sbjct: 3961 DELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRDAESLKLDR-EAF 4019
Query: 659 EAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKV---------DKSALTENGEGC 799
E E++ L+ KT LER A ++ ++ HE + +E ++ L +N E
Sbjct: 4020 ENEREVLKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEM 4079
Query: 800 EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGH 979
+ +KQ EK D++ + SL+ ++L + +KQ +E+ + LE L
Sbjct: 4080 QEQKQEMEKERHDMDQSRKSLD----KNLKMMKLQKQVIEEEKNKLEQMKIELEK----- 4130
Query: 980 EAEIERKLEASNLTHNDELHKE----KDDKESIMNDLDHVKAERQVLESKVSDMETTYST 1147
EA+ RK++ L K K +KES + + K E+++L+ M+ +
Sbjct: 4131 EADEIRKIKEETQNERQRLEKMTEELKKEKESFTHLAEDTKTEKKILDK----MKVANES 4186
Query: 1148 LNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQT 1327
L +LQ+ E+ LE +++ + K+ D +E EK+
Sbjct: 4187 LMADLQK----------EKSNLEEMRENISKQTED------------------SEKEKEK 4218
Query: 1328 LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKES------KEKQDLEKRV 1489
++ R ELE+ L +I+ E+ E N ES K+ +DL+ ++
Sbjct: 4219 IRLREDELEQ-----------LQAEIHKQQGEIK--MEKSNNESERAAIIKDVKDLQHKM 4265
Query: 1490 LELTSKLE 1513
L LE
Sbjct: 4266 FSLDRDLE 4273
Score = 71.6 bits (174), Expect = 1e-09
Identities = 107/531 (20%), Positives = 221/531 (41%), Gaps = 28/531 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
++ ++ + E T + EL N + K+ I ++R+ +E K L+ + D E + + ++
Sbjct: 2779 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2838
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++++ +IK +K+ + D + +
Sbjct: 2839 ---RRNNEEMVIKLQNEKKDIETSTDR-----------------------------IRDE 2866
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEED 544
E N+ +L + L+ ++D L K+ + + ++ LES++R + ++E
Sbjct: 2867 EANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKER 2923
Query: 545 EVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
E+LE+ L+ K E+E KEK S E E ++E++G+ KT R
Sbjct: 2924 EILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIK 2977
Query: 716 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 895
MD EL++ +++ EN E +KQ ++ + D++
Sbjct: 2978 KEMD-----ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKI 3011
Query: 896 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDK 1057
K L+K D E + + ++ +E + ++ +E S DE + K
Sbjct: 3012 EQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQK 3071
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
+ + +D D ++ ER LE ++M L ++++Q ER+ LE +K L
Sbjct: 3072 QRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLS 3131
Query: 1238 KRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL---- 1372
K+ DLE E + +D ++E++ +K+ + ELE+ L
Sbjct: 3132 KQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQ 3191
Query: 1373 --TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3192 ENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 71.6 bits (174), Expect = 1e-09
Identities = 111/536 (20%), Positives = 234/536 (43%), Gaps = 60/536 (11%)
Frame = +2
Query: 86 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERK-KDDNNAIIKKALDKRISD 253
K + NDRN++E + LE ++L + + DE L++K K+ N K +K I +
Sbjct: 9592 KKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVE 9651
Query: 254 LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKE----KDDK 421
+ A +Q +D +++ E + E+++ K+++
Sbjct: 9652 -RLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNER 9710
Query: 422 TALIKDLVAAEPGKRTVNEIVSHLESKSRSL----------------KEHFLREEEDEV- 550
L + + K+ + I+ + L K+ L +E +E+
Sbjct: 9711 ETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEIN 9770
Query: 551 ------LERSASNLAIMKAIREEELRKEK---DGKSALVE-NGEGCEAE-KQGLEKTVLE 697
+R A ++ +EE+L +K + + L E NG+ E + K LE +
Sbjct: 9771 HKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEIN 9830
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT-IPSLNDAL 874
++ L T+ +E++ KEK A+T + E E K+ L E T + L
Sbjct: 9831 QKIEELQTL----QEQIMKEKEKAEAMTIKLK-MEREDLDQIKSELVREKTEVDHEQKKL 9885
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
D+ + EK+ LEK S++ + + E +E++ K++ ++L +D + K K+
Sbjct: 9886 NDDIKMIEQEKEDLEKMKSEIMTQKQEM----EKERSELDNKIQQTDLEKHD-IEKSKEI 9940
Query: 1055 KESIMNDLDHVKAERQVLES-------KVSDMETTY----STLNNELQQKMDDNEAFLNE 1201
E +M +++ + E Q+ + K++D + S L NE ++ + NE E
Sbjct: 9941 VEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKE 10000
Query: 1202 RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------DYNEAEKQTLKKR--ISELEE 1357
R+ L+ ++ LEK ++++ E + K+D D E + +K+R + + +E
Sbjct: 10001 RETLKEMEAHLEKEKEEMKSITE--ETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKE 10058
Query: 1358 AISILTDKAKKLLKDINIWLSEVTE----LQEDLNKESKEKQDLEKRVLELTSKLE 1513
I+ + ++ + + + +S+ E Q+++ +E K ++ + R++E+ +K E
Sbjct: 10059 DINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAE 10114
Score = 71.6 bits (174), Expect = 1e-09
Identities = 109/563 (19%), Positives = 243/563 (43%), Gaps = 50/563 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LER 196
D E+ L++E +D+ K + +N+L +K + +LE T + E +E+
Sbjct: 13323 DLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEK 13382
Query: 197 KKDD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXX 346
++++ N IIK ++L+ I K + A +R Q + + L
Sbjct: 13383 EREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTL 13442
Query: 347 XXIVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
+ + + L LQK+K++ L ++ + AE K V L+ + +
Sbjct: 13443 VQTEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQK 13499
Query: 509 SLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----E 661
+++ + + E +VLE+ S L + + E++++E++ L+E E C E
Sbjct: 13500 EVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE 13559
Query: 662 AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
+EKQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L
Sbjct: 13560 SEKQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNL 13616
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQ 970
+ I + L + A++Q E K+ D+ E TD
Sbjct: 13617 KEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDAS 13676
Query: 971 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL----ESKVSDMETT 1138
+ + + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 13677 QKFQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEM 13735
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
LNNE+++ E+D L+ K ++ ++ + E + + + +++
Sbjct: 13736 RDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE------ 13789
Query: 1319 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 1498
+ L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 13790 -EKLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQL 13848
Query: 1499 TS-KLEKCICGARDGLSTIKEAW 1564
+ E+ I D ST KE +
Sbjct: 13849 KQIEQEREIQRKADVTSTEKEMY 13871
Score = 70.9 bits (172), Expect = 2e-09
Identities = 120/625 (19%), Positives = 268/625 (42%), Gaps = 75/625 (12%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNE----KDDKKCIVNDR-NILEAAKQALEYKVADLEAAKT 172
L+ ++ +F+A ++ ++ L + K+D+K + + N++E +A + +++ K
Sbjct: 10345 LQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKA---EPEEIKKEKE 10401
Query: 173 TLNDELERKKDDNNAII---KKALDKRISDLKADAPQRDQE----DDMNALIXXXXXXXX 331
N+E E ++++ I+ +K L + S+L+ + D E +D +I
Sbjct: 10402 KENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKED-- 10459
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
+ ++ I+ +++++E+ + I+ + H KS+
Sbjct: 10460 --------LEKMKSEIMKQRQQMEEERSELDNKIQQ-----------TNLEKHDIEKSKE 10500
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV 691
+ E + E E++ ++ + K + E +K D ++ LV+N + E + ++K V
Sbjct: 10501 IVEKLMVEVEEQ-----RKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKK-V 10554
Query: 692 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
E +T+ + E L+KEK + ++ E + + + + + + + + + D
Sbjct: 10555 DEEIKKERETLREM-EIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDL 10613
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK---------LEASNLTH 1024
L+++ + + E L++R + +A+ + ++ E E ERK +E
Sbjct: 10614 LEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAE 10673
Query: 1025 NDELHKEKDDK-ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE 1201
E+ +EK+++ E M + V+ ER+ L S+++ S +++E ++ DD + E
Sbjct: 10674 LQEIMQEKEEEDEEEMRVI--VEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQE 10731
Query: 1202 RDGLEAVK-------QGLEKRVLDLEATI-------HDIE-------------------M 1282
++ LE +K Q +E+ +L+ I HDIE +
Sbjct: 10732 KEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDI 10791
Query: 1283 KTGKDD---------------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 1417
+ K++ N+A+ Q +RI E++E I K K+ LK++ L
Sbjct: 10792 RLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHL 10847
Query: 1418 SEVTELQEDLNKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 1591
+ E + +E+ ++K+DLEK ++ +K + + RD L +E +
Sbjct: 10848 RKEKEEMRSVIEETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHK 10900
Query: 1592 WVPFEDLVQGFSRKTSPL---DITK 1657
W + + F + S D+TK
Sbjct: 10901 WTQLQQRIDEFDAQVSKQKEEDLTK 10925
Score = 69.3 bits (168), Expect = 7e-09
Identities = 116/533 (21%), Positives = 226/533 (42%), Gaps = 17/533 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ +E KQ +E + +++ ++ +L+++
Sbjct: 4875 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 4934
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++ K + K+ ++ + L+ + ++E D + I N
Sbjct: 4935 QKKMK-----LQKQMFEEEKNKLEQMKIELEREADEISKIKEE-------------TQNK 4976
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
+ + EEL +EK+ L +D + K+ ++E+ ES L + E
Sbjct: 4977 RQRLEKMTEELIREKESLAHLAED---TKTEKKILDEMKVANESSMADL------QREKS 5027
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSAL--VENGEGCEAEKQGLEKTVLERRASNLDT 721
+LE N++ +K + E K K + L ++ + K +EKT +E + +
Sbjct: 5028 ILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIR 5087
Query: 722 MDAIHEEELRKEKVD-----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
EL+K+ D K LTE E + D+E L D L+RD
Sbjct: 5088 EKQNMMTELKKKSEDVEIQMKEILTEK----ELLHNDRKLLTRDVENLQQKLID-LERDS 5142
Query: 887 DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDE-----LHKEK 1048
R+ +++A E ++ EA TD Q + EIE+ KLE + E + KE+
Sbjct: 5143 KRLKLDREAFE---NEKEAMKQMKTDLQIQAD-EIEKIKLETQHDRQRVEEMAAQIQKER 5198
Query: 1049 DDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 1228
D I N ++ + VL K D+E ++ ++ + R L VK+
Sbjct: 5199 D---KINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKE 5255
Query: 1229 GLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDIN 1408
LEK+ E T+ +I+ + + NE + + + I EE ++ D+ +L
Sbjct: 5256 DLEKQ---KENTLAEIQKEREDVEKMNENITREMHE-IKHQEEQMNQKQDELDQL----- 5306
Query: 1409 IWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEKCICGARDGLSTIK 1555
+E+ LQ++L KE K++ + R S+L+K D + T+K
Sbjct: 5307 --KTEIQNLQQELEKEKEIIMKDRSQFDLR----QSELDKQQTNMNDIMETMK 5353
Score = 68.9 bits (167), Expect = 9e-09
Identities = 117/544 (21%), Positives = 231/544 (42%), Gaps = 39/544 (7%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDD--------KKCIVNDRNILEAAKQALEYKVADL 157
Q AD E + EL KD+ +K V+ + + +++ E +L
Sbjct: 1711 QTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIEL 1770
Query: 158 EAAKTTLN---DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 328
E A+ LN ++E +K A +K L K +L+A ++ ED+ AL
Sbjct: 1771 EKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ--RKMMEDEKRALENMKYELQ 1828
Query: 329 XXXXXXXXIVSNLEVNILILH----------EELQKEKDDKTAL-------IKDLVAAEP 457
N+ + EEL+K++ D L IKDL
Sbjct: 1829 RESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDL----E 1884
Query: 458 GKRTVNEI-VSHLESKSRSLKE-HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 631
R +NE+ ++ +++KS L++ L ++ + +E S + I RE +L++ + +
Sbjct: 1885 NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKI----REYDLQQMQTDLN 1940
Query: 632 ALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG-EGCEAE 808
+ E Q ++ V ++ + D I E+ K+ D T+N + + E
Sbjct: 1941 RQ-------QKEMQDIQNAVFMEKSELKKSQDEIAEQ--LKQVGDMMQFTQNEKDNLDRE 1991
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRV-MAEKQALEKRCSDLEAKNASLTDNQEGHEA 985
+ + L +E + L L R+L+ + + +K+ L ++ + + + + D Q+ +
Sbjct: 1992 RAAIIEQKLQMERDMTHL---LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQM 2048
Query: 986 EI--ERKLEASNLTHNDELHKEKDDKESIMNDL--DHVKAERQVLESKVSDMETTYSTLN 1153
+I ER+ E L + +EKD ES++ L D K L K +E L
Sbjct: 2049 KINLEREKEEMQL-QRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK-QKLEDAAVELQ 2106
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 1333
E + M+ E +R+ ++ ++ G+EK+ E T D++ K+ E ++Q ++
Sbjct: 2107 KERDEIMNIAEETKRKREDVDKIRVGIEKQ----EITFKDLKADLQKEAAIVENQRQAVQ 2162
Query: 1334 K---RISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
K + ++E I +L+++I + E+Q +++KE +E + + + TS
Sbjct: 2163 KDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETS 2222
Query: 1505 KLEK 1516
KL +
Sbjct: 2223 KLRE 2226
Score = 68.9 bits (167), Expect = 9e-09
Identities = 104/526 (19%), Positives = 213/526 (40%), Gaps = 32/526 (6%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKC----IVNDRNILEAAKQALEYKVADL------ 157
L+ V D L ++LL E++ K I ++++L KQ + + D+
Sbjct: 3289 LKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQ 3348
Query: 158 ----EAAKTTLNDELERKKDDNNAIIKKALDK--RISDLKADAPQRDQEDDMNALIXXXX 319
E L + R++D+ A K +++ R+ K + + +E +
Sbjct: 3349 LRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKD 3408
Query: 320 XXXXXXXXXXXIVSNLEVNILILHEELQKEK---DDKTALIKDLVAAEPGKRTVNEIVSH 490
I +++I EL KE+ +++T ++ KRT E+
Sbjct: 3409 RANLEKEKSEMIAQKHQMDI-----ELNKERGLIEERTQMLNTYEKEMDQKRTALEV--- 3460
Query: 491 LESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E K + ++EE++++ L+R A ++ +K E+ R E+ + EN
Sbjct: 3461 -EMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLK----EKTRNERQSLEKMAEN-- 3513
Query: 653 GCEAEKQGLEKTVLERRASNLDTMDAIHEE---ELRKEKVDKSALTEN----GEGCEAEK 811
E EK L + + + D M +HE +++KEK + + E+ E ++EK
Sbjct: 3514 -LEKEKDDLAHLAEDTKRKD-DEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEK 3571
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
K ++ E + + + R + +K +E + + KN L
Sbjct: 3572 ----KKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMT--------- 3618
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQK 1171
EL K+ +D E M + V E+++LES ++ L +L
Sbjct: 3619 -------------ELTKQSEDVEIQMKE---VLTEKELLESDRKLLKKDVENLQQKLLII 3662
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 1351
D+E+ +R+ LE K+ L++ DL+ +IE K + + + + +I +
Sbjct: 3663 ESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE-KIKLETQHERQRVEEMTAQIQKD 3721
Query: 1352 EEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
E + + D + + DI ++ + Q++L++ E Q+L++ +
Sbjct: 3722 REYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQEL 3767
Score = 68.6 bits (166), Expect = 1e-08
Identities = 121/564 (21%), Positives = 227/564 (40%), Gaps = 64/564 (11%)
Frame = +2
Query: 17 KVADFEATIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 193
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 12477 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 12534
Query: 194 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 12535 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 12576
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 12577 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 12636
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 721
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 12637 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 12692
Query: 722 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 874
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 12693 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 12750
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKLEA 1009
+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 12751 EESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRERE 12810
Query: 1010 SNLTHNDELHKEKDD----KESIMNDLDHV----------KAERQVLESKVSDMETTYST 1147
D+L KEK+D KE I + +H+ K E + K+ M+T
Sbjct: 12811 EIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQV 12870
Query: 1148 LNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATIHD 1273
N L++ M D + ER+ + A+ K+ ++ +L +++ D
Sbjct: 12871 KTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 12927
Query: 1274 IE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 1444
IE +K + N+ +K LK R ELE I KK K+ ++ E+Q +
Sbjct: 12928 IESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQRE 12977
Query: 1445 LNKESKEKQDLEKRVLELTSKLEK 1516
K +LE++ EL +K+EK
Sbjct: 12978 RKALEKMNAELERKSTELKNKIEK 13001
Score = 65.9 bits (159), Expect = 7e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = +2
Query: 461 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 637
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 638 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 817
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 818 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 998 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 1126
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 1127 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 1303
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 1304 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 1462
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 1463 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 1627
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 1628 RKTSPLDITKT-----CDAVDISEDST 1693
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 1e-07
Identities = 118/608 (19%), Positives = 236/608 (38%), Gaps = 108/608 (17%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKT 172
++ D E + LN+ LN+ K ++ ++ +E K ++ + DL+ +T
Sbjct: 1879 EIKDLE-NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1937
Query: 173 TLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 346
LN + + +D NA+ K L K ++ A Q Q DM
Sbjct: 1938 DLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK--------- 1985
Query: 347 XXIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
NL+ I+ ++LQ E+D L ++L + + K+ V LE SL
Sbjct: 1986 ----DNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRD 2041
Query: 524 FLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKT 688
E+ ++ LER + + + EE K + L E+ E AEKQ LE
Sbjct: 2042 MQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDA 2101
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDK----------------------SALTENGEGC- 799
+E + + M+ E + ++E VDK +A+ EN
Sbjct: 2102 AVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAV 2161
Query: 800 --------------EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 937
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +L
Sbjct: 2162 QKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDEL 2217
Query: 938 EAKNASLTDNQEGHEAEIER----KLEASNLTHNDELHKEKDDKESIMNDLD-------- 1081
E + + L ++++ + E+ + E + N EL E KE + +L+
Sbjct: 2218 EQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRE 2277
Query: 1082 -------------------------HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
++A++ K ++T L+++ + E
Sbjct: 2278 NEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEME 2337
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKK 1336
+ E + +E K+ + ++ E+ + +EM+ Y E ++Q +K
Sbjct: 2338 SLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEK 2397
Query: 1337 RISELEEAISILTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVL 1492
I ++ + I + ++ K++ I V E Q+ + ++SK E ++ K++
Sbjct: 2398 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKIN 2457
Query: 1493 ELTSKLEK 1516
S++EK
Sbjct: 2458 ADLSEVEK 2465
Score = 63.9 bits (154), Expect = 3e-07
Identities = 103/563 (18%), Positives = 240/563 (42%), Gaps = 74/563 (13%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 226
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 10481 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 10540
Query: 227 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIV 358
K +D+ I + + + +++++ ++I +
Sbjct: 10541 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 10600
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 538
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 10601 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 10653
Query: 539 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 700
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 10654 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 10709
Query: 701 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 838
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 10710 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 10764
Query: 839 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1015
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 10765 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 10823
Query: 1016 LTHNDELHKEKDDKESIMNDLDHVKAERQVLES--------KVSDMETTYSTLNNELQQK 1171
+ + K +KE++ H++ E++ + S K D+E + +N + Q
Sbjct: 10824 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 10883
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 1330
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 10884 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 10943
Query: 1331 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 1459
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 10944 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11003
Query: 1460 K----EKQDLEKRVLELTSKLEK 1516
K EK+DLEK E+ + ++
Sbjct: 11004 KMIEQEKEDLEKMKSEIMKQRQQ 11026
Score = 63.9 bits (154), Expect = 3e-07
Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 16/514 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALE-YKVADLEAA------ 166
+EN F IA L ++ K DK+ I N+ L+ +Q E + AD+ +
Sbjct: 13813 IENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKADVTSTEKEMYT 13872
Query: 167 -KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXX 343
K T ELE K+ IK D + D+ + D E + L
Sbjct: 13873 EKVTYKTELEDSKEK----IKPDRDSTLELTDTDSAKTDGEREAQTL-----------ET 13917
Query: 344 XXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
V L + EEL E ++K +I +L A+ + + L+ + RS +E
Sbjct: 13918 KVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAK-------KDLQKLKEECRSAEEE 13970
Query: 524 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLER 700
+ E LER ++L E+++ E + +++ + E Q +E K ++
Sbjct: 13971 --KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQT 14020
Query: 701 RASNLDTMDAIHEEELRKEKVDKSA-LTENGEGCEAEKQGPEKTVLDLEPTIPS-LNDAL 874
R+ + ++ +E ++ + +T+ E + K+ + V LE T+ S + +
Sbjct: 14021 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMR 14080
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
+++ V K ++ LE + + E E +E L+ + + + L + D
Sbjct: 14081 DMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKS-RNEETLLQLLHD 14139
Query: 1055 KESIMNDLDHVKAERQ----VLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAV 1222
K+ + N LD E + + ++ +ETT + + +
Sbjct: 14140 KDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKD--------------------- 14178
Query: 1223 KQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLK 1399
K+ +E +L L+ T + E++ G DD NE E K +ELE+ + + KK +
Sbjct: 14179 KENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELED-----SKEKKKPDR 14233
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
D ++ L++ + D +E++ + + VL+LT
Sbjct: 14234 DSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 14267
Score = 63.5 bits (153), Expect = 4e-07
Identities = 113/537 (21%), Positives = 220/537 (40%), Gaps = 46/537 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL--------- 178
+ E T NDE+ EK I + + +L + LE ADLE K +
Sbjct: 7543 NMEKTYEQQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLA 7599
Query: 179 -NDELERKKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXX 334
N+ LER+K D II+ +A +R ++ A A +RD E+ M +
Sbjct: 7600 ENELLEREKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQE 7658
Query: 335 XXXXXXI--------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH 490
+ + L+ ++L EL+K K D + DL ++T +EI+ H
Sbjct: 7659 ASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKH 7712
Query: 491 ---LESKSRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENG 649
+SK+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 7713 EKDTDSKTRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM---- 7767
Query: 650 EGCEAEKQGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEK 811
K V+ +R D M+ I EE+ +E+ + L N + +
Sbjct: 7768 -----------KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDF 7812
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ + +LE ++ D++R++ E + + +L+ E+
Sbjct: 7813 ELLLERTANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EM 7853
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTL 1150
ER++E S + DE K + + + D+ ++ L ++ ++E + L
Sbjct: 7854 ERRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAEL 7912
Query: 1151 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL 1330
+ Q++ E ER+ LE +K + + D+E +E K++ + Q
Sbjct: 7913 AEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKY 7972
Query: 1331 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 1498
K+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 7973 KEELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8025
Score = 63.5 bits (153), Expect = 4e-07
Identities = 118/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = +2
Query: 2 QALENKVAD-FEATIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 172
Q LE KV D + T T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 14254 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 14313
Query: 173 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 274
+ + LER+++ + + L ++ +K + Q
Sbjct: 14314 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 14373
Query: 275 ----RDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDL 442
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 14374 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 14430
Query: 443 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 619
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 14431 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 14490
Query: 620 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 733
D K+ +EN E E E L++T ER T D
Sbjct: 14491 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 14549
Query: 734 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 910
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 14550 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 14597
Query: 911 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVK 1090
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 14598 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 14638
Query: 1091 AERQVLESKVSDMETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 1249
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 14639 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 14698
Query: 1250 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 1420
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 14699 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 14758
Query: 1421 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 1513
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 14759 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 14800
Score = 61.6 bits (148), Expect = 1e-06
Identities = 89/490 (18%), Positives = 194/490 (39%), Gaps = 3/490 (0%)
Frame = +2
Query: 98 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 277
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 278 DQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 457
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 458 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 637
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 638 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEK 811
+ E E ++ ++ +T R +L+ + ++E L + K L + E +K
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
D ++ + ++ + L++ +DL + + D Q E
Sbjct: 1916 ------------------DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFME- 1956
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAER-QVLESKVSDMETTYSTLNNELQQ 1168
+ +L+ S ++L + D + N+ D++ ER ++E K+ LN EL+
Sbjct: 1957 KSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELES 2016
Query: 1169 KMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISE 1348
+ LNE+ LE + L + + DLE +++ ++ + + ++Q++ + +
Sbjct: 2017 LKLVKKEVLNEKRLLEDCRISLMRDMQDLE----QMKINLEREKEEMQLQRQSIAEEKDK 2072
Query: 1349 LEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICG 1528
LE + L + +KL D ++ + +L KE E ++ + ++K G
Sbjct: 2073 LESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVG 2132
Query: 1529 ARDGLSTIKE 1558
T K+
Sbjct: 2133 IEKQEITFKD 2142
Score = 61.2 bits (147), Expect = 2e-06
Identities = 118/559 (21%), Positives = 227/559 (40%), Gaps = 54/559 (9%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--------- 160
LE A E L+ EL K+ I ++R LE K L+ K D+E
Sbjct: 7144 LEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYE 7203
Query: 161 ----AAKTTLNDELERKKDDNNAIIKKA------LDKRISDLKADAPQRDQEDD---MNA 301
A + + N +++ D+ NA ++K D+ + K + + E + A
Sbjct: 7204 KQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKARAETERVKQGA 7263
Query: 302 LIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIK--DLVAAEPGKRTVN 475
I + ++ N+ E ++K+K + + DL+ A+ K+
Sbjct: 7264 KIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEE 7323
Query: 476 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG 655
+ +ES+ +E + +E LE + + I + L+ E DGK V+N
Sbjct: 7324 MVKQKIESEREIQQEKKKLQRSEEELEDKMQKIK-REMIELKLLQDETDGKRKDVDN--- 7379
Query: 656 CEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL 835
+ + R+ L+ M A E +K +VD+ L + E K ++
Sbjct: 7380 --------KMRQVARKRDELEKMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE 7431
Query: 836 DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL--EAKNASLTDNQEGHEAEIERKLEA 1009
++ + A +R D + EK+ + R L EA+ AS HE E+ + E
Sbjct: 7432 HMQ------SHAEERAGD--LGEKEPVNTRIQRLIQEAEKASKMAWSTKHEPEMRMQREV 7483
Query: 1010 S----NLTHND----------ELHKEKDDKESIMNDLDHVKAERQVLE-------SKVSD 1126
S ++ D E+ ++ + +++ + ER LE + +
Sbjct: 7484 SVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKN 7543
Query: 1127 METTYSTLNNELQ---QKMDDNEAFLN-ERDGLEAVKQGLE--KRVLDLEATIHDIEMKT 1288
ME TY N+E+Q Q+++ ++ L+ ER+ LE + LE K+++ L+ + K
Sbjct: 7544 MEKTYEQQNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALD------KQKL 7597
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILT-DKAKKLLKDINIWLSEVTELQEDLNKESKE 1465
+++ E EK + K I LE T ++A + + E+ + E L+ E +
Sbjct: 7598 LAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQ 7657
Query: 1466 KQDLEKRVLELTSKLEKCI 1522
+ + +++EL +++K I
Sbjct: 7658 EAS-KNQMVELKRQIDKLI 7675
Score = 60.8 bits (146), Expect = 2e-06
Identities = 117/551 (21%), Positives = 209/551 (37%), Gaps = 81/551 (14%)
Frame = +2
Query: 56 DELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK---TTLNDELERKKDD--NN 214
++LL E +K+ ND + E K+ ALE + D+ K +L +E+ K+ + N
Sbjct: 13219 NDLLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNK 13278
Query: 215 AIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
K + DL+ R Q+ +++ I ++LE
Sbjct: 13279 ETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR----------NDLESMK 13328
Query: 380 LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK---EHFLREEEDEV 550
+L EE ++ +D+ P K + LE + +K EH +E E
Sbjct: 13329 TLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKERE--- 13385
Query: 551 LERSASNLAIMKAIRE--------EELRKEKDGKSALVENGEGCEAE----KQGLEKTVL 694
E N I+K+ E E ++E GK A +E+ E A+ ++ V
Sbjct: 13386 -EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 13444
Query: 695 ERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
+ ++ + E EL+ + K+ L E EAEK E + L+ + D
Sbjct: 13445 TEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDI 13504
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL---------------- 1003
+ + +E+ LEK S+L + L + + + E+ER L
Sbjct: 13505 MTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIES 13560
Query: 1004 ----------EASNLTHNDELHKEK----DDKESIMNDLDHVKAER-------QVLESKV 1120
E L E+ E+ DK I + +H++ E+ L+ ++
Sbjct: 13561 EKQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEI 13620
Query: 1121 SDMETTYSTLNNELQQKMDDNEAF-----LNERDGLEAVKQGLEKRVL-----------D 1252
+ LN E++ K + E + D L+ L + ++
Sbjct: 13621 KRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQ 13680
Query: 1253 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 1432
L+ T D E +T D+ +T ++R LEE ++ T K ++K + SEV E
Sbjct: 13681 LKTTSRDAETQTSLDE-----ITKTDERRQRALEETVA-TTAKQPIVIKLEDTLTSEVQE 13734
Query: 1433 LQEDLNKESKE 1465
+++ LN E KE
Sbjct: 13735 MRDHLNNEIKE 13745
Score = 60.5 bits (145), Expect = 3e-06
Identities = 112/543 (20%), Positives = 217/543 (39%), Gaps = 48/543 (8%)
Frame = +2
Query: 14 NKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN-DEL 190
+K+ + +A + EL K D K ++D LE + + D ++ L E+
Sbjct: 7672 DKLIELKADLLQQQTELKKTKADLKQQMDD---LEKTRSEILKHEKDTDSKTRELELIEI 7728
Query: 191 ERKKDDNNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXXIV 358
+R+KDD I+K L+KR + L+++ ++D + M +I
Sbjct: 7729 QRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANAT 7788
Query: 359 SNLE---VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSR 508
+ + IL +Q + D +TA ++D +A +R V E+V + R
Sbjct: 7789 EEINRERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVR 7847
Query: 509 SLK---EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQG 676
+LK E + + + E+ E+ I + I++ ++R+ G +E + E +
Sbjct: 7848 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 7907
Query: 677 LEKTVLERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT 829
+ + E++ + +H+E E+ +EK D E E +++ E T
Sbjct: 7908 MRAELAEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFT 7967
Query: 830 -VLDLEPTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
+ + + S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +
Sbjct: 7968 DIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-K 8026
Query: 998 KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 1177
K E DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8027 KGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDL 8086
Query: 1178 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------ 1339
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8087 FRSELQRQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKI 8143
Query: 1340 ----------ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
I + + IL D + +D + E +L E D+E+ V
Sbjct: 8144 RFDIANARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLV 8199
Query: 1490 LEL 1498
LE+
Sbjct: 8200 LEV 8202
>ref|XP_005159740.1| PREDICTED: titin isoform X3 [Danio rerio]
Length = 15590
Score = 101 bits (251), Expect = 2e-18
Identities = 132/600 (22%), Positives = 266/600 (44%), Gaps = 39/600 (6%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRN--------ILEAAKQALEYKVADL 157
Q +E A + +N+ L+ E + K ++N++N +++ K LE + DL
Sbjct: 6058 QRVEEMTAQIQKDRDKINN-LIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDL 6116
Query: 158 EAAKTTL---NDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXX 316
E ++ L ++LE++K++ A I+K L+K ++ + + + QE+ MN
Sbjct: 6117 EKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQ----- 6171
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKRTVNEIV 484
+ L+ I L +EL+KEK+ ++ L + + + +N+I+
Sbjct: 6172 ---------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIM 6222
Query: 485 SHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
++++ + L K+ EE+ + +E+ N+ + +E+L+ K K + E E
Sbjct: 6223 ETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLE 6282
Query: 662 AEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTENGEGCEAEKQGPEK 826
K LE+ + R +T + EEL+KE+ D + L E+ + EK ++
Sbjct: 6283 QMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED---TKREKNSLDE 6339
Query: 827 TVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLE 1006
+ E ++ L Q++ + K+ + K+ D+E + D E E+E+ L+
Sbjct: 6340 MKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DKIRLREDELEQ-LQ 6390
Query: 1007 ASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
A E+HK++ + E + +++ ER + V D+++ +L+ + + D E
Sbjct: 6391 A-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE 6440
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI 1342
AF NE++ L+ +K LE+ ++E T H+ EM + N KQ K ++
Sbjct: 6441 AFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKV 6500
Query: 1343 ------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
E+E+ + K L +D+ + ++ L+E+ NK + K LE+ E+ S
Sbjct: 6501 MIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-S 6559
Query: 1505 KLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 1684
K+++ R L + A + E L + RK LD K + +++
Sbjct: 6560 KIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVLDKIKVANESTLAD 6610
Score = 99.8 bits (247), Expect = 5e-18
Identities = 131/591 (22%), Positives = 260/591 (43%), Gaps = 87/591 (14%)
Frame = +2
Query: 5 ALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTT--- 175
A+ V D + + +L+ +L + K D++ N+R +L+ K L+ K ++E K
Sbjct: 4709 AIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQH 4768
Query: 176 -------LNDELERKKDDNNAIIKKA--LDKRISDLKADAPQRDQ--EDDMNALIXXXXX 322
+ ++++++D N +I++ D ++++K + ++ + E D + L
Sbjct: 4769 DRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHD 4828
Query: 323 XXXXXXXXXXIVSNLEVNILILHEELQKEKDDK-------TALIKDLVAAEPGKRTVNEI 481
NLE I E+QKE++D T I D+ E + +
Sbjct: 4829 LEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDE 4888
Query: 482 VSHLESKSRSLKEHFLREEEDEVLERSASNLA-------------IMKAIREEELRKEKD 622
+ L+++ ++L++ +E+E + +RS +L IM+ ++ E + +KD
Sbjct: 4889 LDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKD 4948
Query: 623 GKSALVENGEGCEAEKQG----------------LEKTVLERRASNLDTMDAIHEEELRK 754
K E + E EK L+K VLE S L+ M EL +
Sbjct: 4949 -KEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKI----ELER 5003
Query: 755 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 934
E V+ + E + E+Q EK L+ L + +++ + K A E +D
Sbjct: 5004 EAVEIRKIKEE---IQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLAD 5060
Query: 935 LEAKNASLTDNQEG---HEAEIERKLEASNLTHND------ELHKEKDDKESIMNDLDHV 1087
+ + ++L + +E ++E K E L ++ E+HK++ + E + ++
Sbjct: 5061 ILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEK---EKINI 5117
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE--- 1258
++ER + V D++ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 5118 ESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIK 5177
Query: 1259 -ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AK 1387
T HD +++ +D+ N E+ L ++ ++EE I SI +DK +
Sbjct: 5178 LETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLE 5237
Query: 1388 KLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 1516
K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 5238 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 5288
Score = 99.4 bits (246), Expect = 6e-18
Identities = 124/547 (22%), Positives = 230/547 (42%), Gaps = 48/547 (8%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 217
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 4608 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 4667
Query: 218 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEE 397
K+ R+ + + + Q + + V +L+ + L +
Sbjct: 4668 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 4727
Query: 398 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 553
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 4728 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 4780
Query: 554 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 706
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 4781 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 4840
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 865
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 4841 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 4900
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 4901 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 4960
Query: 1040 KEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
KEK D ++S+ DL +K ++QVLE + S +E L E + E NER
Sbjct: 4961 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 5020
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 1369
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 5021 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 5077
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 1525
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 5078 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 5137
Query: 1526 GARDGLS 1546
RD S
Sbjct: 5138 LDRDAES 5144
Score = 94.0 bits (232), Expect = 2e-16
Identities = 133/541 (24%), Positives = 243/541 (44%), Gaps = 54/541 (9%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 5668 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 5727
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5728 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5766
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5767 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5824
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 718
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 5825 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 5884
Query: 719 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 883
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 5885 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 5933
Query: 884 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1057
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 5934 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINI 5990
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
ES ER + V D++ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 5991 ES----------ERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 6040
Query: 1238 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 1363
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 6041 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 6100
Query: 1364 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 1513
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 6101 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 6160
Query: 1514 K 1516
+
Sbjct: 6161 E 6161
Score = 91.3 bits (225), Expect = 2e-15
Identities = 138/568 (24%), Positives = 250/568 (44%), Gaps = 63/568 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 166
+ LE+ + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3639 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3698
Query: 167 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 313
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3699 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3752
Query: 314 XXXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 475
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3753 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3796
Query: 476 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3797 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3851
Query: 653 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 808
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3852 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3905
Query: 809 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 979
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3906 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQ 3965
Query: 980 -EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 1156
+AEI ++ E+ KEK + ES ER + V D++ +L+
Sbjct: 3966 LQAEIHKQQR--------EIEKEKSNIES----------ERAAIIKIVEDLQHKIISLDR 4007
Query: 1157 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIE-------MKTGKDDD 1303
+ + D EAF NER+ L+ +K LE+ ++E T HD + T + D
Sbjct: 4008 DAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDK 4067
Query: 1304 YNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLNKE 1456
N ++T L ++ ++EE I SI +DK +K ++ SE+ +++EDL K+
Sbjct: 4068 INNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQ 4127
Query: 1457 --------SKEKQDLEKRVLELTSKLEK 1516
KE++DLEK +T ++ +
Sbjct: 4128 KENTLAEIQKEREDLEKMNENITIEMHE 4155
Score = 91.3 bits (225), Expect = 2e-15
Identities = 102/535 (19%), Positives = 239/535 (44%), Gaps = 32/535 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 4917 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 4976
Query: 188 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXXI 355
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 4977 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5036
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 529
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 5037 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5096
Query: 530 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 667
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 5097 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 5155
Query: 668 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
K+ L+ KT LER A ++ + E + +++V++ A + E E D+
Sbjct: 5156 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 5213
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLT 1021
+ N ++ + + ++K LEK DLE + L +E E + E L
Sbjct: 5214 --VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA----- 5266
Query: 1022 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
E+ KE++D E+I ++ +K + + + K +++ + + N Q+ + E
Sbjct: 5267 ---EIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5323
Query: 1190 FLNERDGLEAVKQGLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEA 1360
+ +R L+ + L+K+ + D+ T+ + + KD + E +KQ ++K ++++
Sbjct: 5324 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 5383
Query: 1361 ISILTDKAKKLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
L + KK+ ++ E +L++ +L +E+ E +++ +LEK
Sbjct: 5384 RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 5438
Score = 89.4 bits (220), Expect = 6e-15
Identities = 114/525 (21%), Positives = 236/525 (44%), Gaps = 44/525 (8%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE K LE YKV DLE K E++++
Sbjct: 5212 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKE 5271
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5272 REDLEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5310
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5311 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5368
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT------VLER 700
+ + +E+ N+ + +E+ +K K K E E K LE+ + E
Sbjct: 5369 QKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEE 5428
Query: 701 RASNLDTMDAIHEEELRKE----------KVDKSALTEN---GEGCEAEKQGPEKTVLDL 841
+ ++ + EE +R++ K +K L E E A+ Q + + ++
Sbjct: 5429 TQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEM 5488
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNL 1018
I L + + + ++ + L+K ++++ + + + + E+E + E N+
Sbjct: 5489 RENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNM 5548
Query: 1019 THNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
EL K+ +D E I+ + + + +R++L V +++ L + ++ D E
Sbjct: 5549 M--TELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 5606
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS 1366
AF NE++ ++ +K L+ + ++E I+++T D E ++K ++ I
Sbjct: 5607 AFENEKEAMKQMKTDLQIQADEIE----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE 5662
Query: 1367 ILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLEL 1498
T++ +L + N + E + +Q D + KE+ +LEK EL
Sbjct: 5663 -ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSEL 5706
Score = 87.8 bits (216), Expect = 2e-14
Identities = 122/538 (22%), Positives = 233/538 (43%), Gaps = 24/538 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E++ E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 182 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 340
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 520
I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 521 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 682
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 683 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 832
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1009
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1010 SNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
++++ +++L KE+ ++E I N +K E LE ++ NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 1190 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 1369
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 1543
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 85.9 bits (211), Expect = 7e-14
Identities = 116/534 (21%), Positives = 238/534 (44%), Gaps = 34/534 (6%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLND 184
K+ + + +A L+ EL KD+ + I +R+ +E + L ++ +E + D
Sbjct: 9572 KMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQD 9631
Query: 185 ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSN 364
+ ++ +I +K + +I + + Q +QE N L I N
Sbjct: 9632 KQNHLEEKELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELN 9688
Query: 365 LEVN------ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK 502
+ N + + EL+ EK D K + L E K + ++ L+SK
Sbjct: 9689 KQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSK 9748
Query: 503 -SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
++ KE + ++R + + + + + + K+ L E E + E++ L
Sbjct: 9749 REQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKL 9808
Query: 680 E--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E K +++ A NL+ + + + K ++ ++ L E CE ++ E+ D+E I
Sbjct: 9809 EEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQI 9868
Query: 854 PSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EAS 1012
+ +A L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +
Sbjct: 9869 QNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKA 9928
Query: 1013 N--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL---QQKMD 1177
N L D+L KEK+D N LD ++ E Q + +++ NE+ QQ+++
Sbjct: 9929 NEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLE 9988
Query: 1178 DNEAFLNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 1354
++ +NE G LE ++ EK+ +E + +M E++ L + SELE
Sbjct: 9989 ESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELE 10037
Query: 1355 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ + + + KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 10038 KDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10091
Score = 85.5 bits (210), Expect = 9e-14
Identities = 103/492 (20%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = +2
Query: 71 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 238
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 239 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDD 418
+R+++++ + +++ D+ ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 419 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 598
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 599 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 778
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 779 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 958
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 959 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETT 1138
+ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 1309
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 1310 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 1453
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1454 --ESKEKQDLEK 1483
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 82.8 bits (203), Expect = 6e-13
Identities = 118/537 (21%), Positives = 241/537 (44%), Gaps = 56/537 (10%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
D +LNEK+ K I +D+++LE K LE ++L K ++LE++K++ A
Sbjct: 4079 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVK----EDLEKQKENTLAE 4134
Query: 221 IKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILIL 388
I+K L+K ++ + + + QE+ M + L+ I L
Sbjct: 4135 IQKEREDLEKMNENITIEMHEIKHQEEQMKQ--------------KQDELDQLKTEIQNL 4180
Query: 389 HEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREEEDE 547
+EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE+ +
Sbjct: 4181 QQELEKEKEIIMKDRSEL--DLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQ 4238
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMD 727
+E+ N+ +E+L+ K K + E E K L++ E R +T +
Sbjct: 4239 EMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQN 4298
Query: 728 AIHEEELRKEKVDKSALTENGEGCE-AEKQGPEKTVLD-LEPTIPSLNDALQRDLDRVMA 901
E EK+ K+ + E + AE EK +LD ++ S LQR+ +
Sbjct: 4299 ----ERQSLEKMTKALIKEREDLVHLAEYTKREKEMLDEMQVANKSSMADLQREKRILEE 4354
Query: 902 EKQALEKRCSDLE---AKNASLTDNQEGHEAEIERK-----LEASNLTHN---------- 1027
++ + K+ D+E K+ D + + E++++ +E +N+
Sbjct: 4355 MRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQN 4414
Query: 1028 --DELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
EL K+ +D E I+ + + ++ + +L+ + D++ ++ + + D EA
Sbjct: 4415 MMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDREA 4474
Query: 1190 FLNERDGLEAVKQGLEKRVLDLE----ATIHDIEMKTGKDDDYNEA----------EKQT 1327
F NE++ L+ +K L+ + ++E T H+ + D+ E K+
Sbjct: 4475 FGNEKEVLKQMKTDLQIQADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEE 4534
Query: 1328 LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 1498
++++ E+E+ + K L K++ + + ++E+ NK + K +LEK E+
Sbjct: 4535 MQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADEI 4591
Score = 82.4 bits (202), Expect = 7e-13
Identities = 111/556 (19%), Positives = 242/556 (43%), Gaps = 54/556 (9%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL----------- 157
EN + E + +++ N ++ K + +R ++ KQ L+ + DL
Sbjct: 9851 ENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENV 9910
Query: 158 EAAKTTLNDELERKKDDNNAIIKKA--LDKRISDL-----KADAPQRDQEDDMNALIXXX 316
E +K +L++E + + N I+++ L+K D+ K D Q + +++ A+
Sbjct: 9911 EMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIK 9970
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEE------LQKEKDDKTALIKDL-VAAEPGKRTVN 475
LE ++ ++EE ++ + + + I+++ V A+ ++ ++
Sbjct: 9971 YELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELD 10030
Query: 476 EIVSHLESKSRSLKEHFLREEEDE-VLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I S LE + + + D ++E+ ++L MK+ + ++ +D +S L + +
Sbjct: 10031 QIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIK 10090
Query: 653 GCEAEKQGLEKT--VLERRASNLDTMD---AIHEEELRKEK---VDKSALTENGEGCEAE 808
EK +EK ++ER + ++ + +EEL E+ VD+ L CE E
Sbjct: 10091 EANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQ---CETE 10147
Query: 809 KQGPEKTVLDLEPTIPSLNDAL-------QRD-------LDRVMAEKQALEKRCSDLEAK 946
Q + + ++E + + + L QRD ++ +K+ LEK + + +
Sbjct: 10148 LQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQ 10207
Query: 947 NASLT---DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLES- 1114
L D E EI K ++ + + KE + + ++ ER+ LE
Sbjct: 10208 KQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEV 10267
Query: 1115 --KVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKT 1288
K+ +M+T ++E+ QK+++ L+ +++ + K EA ++M
Sbjct: 10268 NGKIIEMKTKAELEHHEINQKIEE----------LQTLQEQIMKEKEKAEAMTIKLKM-- 10315
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEK 1468
E++ L + SEL + + + KKL DI + E +L++ ++ +K
Sbjct: 10316 ---------EREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10366
Query: 1469 QDLEKRVLELTSKLEK 1516
Q++EK EL +K+++
Sbjct: 10367 QEMEKERSELDNKIQQ 10382
Score = 82.0 bits (201), Expect = 1e-12
Identities = 117/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N ++ E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 9256 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 9315
Query: 188 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 343
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 9316 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 9374
Query: 344 XXXIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 514
L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 9375 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 9429
Query: 515 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 9430 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9489
Query: 680 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9490 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9548
Query: 854 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1030
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9549 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 9603
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 1210
E H+ + + + + + ++ + Q+++ K + +E ++ + ++ N F E++
Sbjct: 9604 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 9663
Query: 1211 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 1390
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 9664 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 9709
Query: 1391 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 1516
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 9710 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 9751
Score = 81.3 bits (199), Expect = 2e-12
Identities = 121/518 (23%), Positives = 225/518 (43%), Gaps = 20/518 (3%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + E +L+ +DDK + NDR+ E LE K
Sbjct: 9063 QDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELK-----------R 9111
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+EL R+ +D + +K L +R D + +RD E+ AL
Sbjct: 9112 EELVRETED---LERKILQQREQD---EMAKRDIENQTEAL------------------E 9147
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
++V+IL E KE ++ V +E K + + L+S+ L+ EE+
Sbjct: 9148 VMKVDILKKRNEFAKEMEN--------VHSERQKLLL--LQGALQSQESELENRVFMEEQ 9197
Query: 542 DEVLERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
+ + A K + E E + E++ L+E + E E+ + K +E+ +L
Sbjct: 9198 KHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR-EKEQLEISKNQIEQEKKDL 9256
Query: 716 DTMDAIHE---EELRKEKV----DKSALTENGEGCEAEKQGPEKTVLDLE---PTIPSLN 865
M + E E LR EK +K+AL + + + K DLE I
Sbjct: 9257 QNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEK 9316
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
++ + R+ ++ ++K S+L+ ++ +E ++E +++ +E+
Sbjct: 9317 KRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIE 9376
Query: 1040 KEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 1219
KE + DL++ KAE Q E K D+ ++ ++Q+K + + L++ +
Sbjct: 9377 KESQRLQDATIDLENAKAEIQRQEDKFEDI------IDIKIQEKEREIKIQLDKE--TKR 9428
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKK 1390
+ + +E +V DLE + D++ + + +D E EKQ LK+ ELE+ + LT + ++
Sbjct: 9429 LSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQE 9488
Query: 1391 LLKDINIWLSEVTELQEDLNKES---KEKQDLEKRVLE 1495
++ N ++ +L EDL KE+ KEK LEK +E
Sbjct: 9489 TEEERNNLMALKNQL-EDLRKENEIVKEKLTLEKSNIE 9525
Score = 80.9 bits (198), Expect = 2e-12
Identities = 111/536 (20%), Positives = 231/536 (43%), Gaps = 46/536 (8%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 11949 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 12008
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 12009 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 12068
Query: 362 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 12069 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 12128
Query: 509 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 664
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 12129 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 12183
Query: 665 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 811
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 12184 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 12243
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 12244 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 12303
Query: 992 --ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 12304 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 12363
Query: 1154 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 1318
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 12364 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 12419
Query: 1319 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 1480
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 12420 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12472
Score = 80.1 bits (196), Expect = 4e-12
Identities = 94/521 (18%), Positives = 225/521 (43%), Gaps = 46/521 (8%)
Frame = +2
Query: 92 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 244
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 11617 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 11676
Query: 245 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEEL 400
I ++K ++++E+ M A + I S LE + E
Sbjct: 11677 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 11730
Query: 401 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 580
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 11731 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 11789
Query: 581 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 706
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 11790 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11849
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 11850 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 11905
Query: 887 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1033
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 11906 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 11965
Query: 1034 LHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGL 1213
+ KEK+ +E V+ ER+ +E S +E S +++E ++ DD + E++ L
Sbjct: 11966 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 12025
Query: 1214 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 1393
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 12026 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 12084
Query: 1394 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 12085 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 12125
Score = 79.3 bits (194), Expect = 6e-12
Identities = 122/575 (21%), Positives = 250/575 (43%), Gaps = 74/575 (12%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K+ E T +++ EK+ ++ V R +E K+ L+ + LE ++ ++ E
Sbjct: 11394 ETKIKIIEMKTKTEPEKIKKEKEKEEEEVM-RAKVEMKKEELDQIKSQLERVRSEIDHEQ 11452
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 11453 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQ 11512
Query: 362 NLEV-------NILILHEEL----QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V +I + EEL QK D++ ++++ + + E+ ++ +
Sbjct: 11513 KLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKE 11572
Query: 509 SLKE---HFLREEED-------------EVLERSASNLA-----------IMKAIREE-- 601
+LKE H +E+E+ E LE+ ++++ ++K REE
Sbjct: 11573 TLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEIN 11632
Query: 602 ----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE--KV 763
+L++ D A V + + KQ K + E R S +T I E + + E K+
Sbjct: 11633 HKWTQLQQRIDEFDAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKI 11689
Query: 764 DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEA 943
K E E A+ + ++ + ++ + + + + ++ +K+ +E+ DLE
Sbjct: 11690 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11749
Query: 944 KNASLTDNQEGHE---AEIERKLEASNLTHND-ELHKE---------KDDKESIMNDLDH 1084
+ + ++ E +E+E K+ + + D E KE ++ K I +
Sbjct: 11750 MKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEE 11809
Query: 1085 VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEAT 1264
+ ERQ + + + S L NE ++ + NE ER+ L+ ++ LEK ++++
Sbjct: 11810 LDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI 11869
Query: 1265 IHDIEMKTGKDD-----DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVT 1429
E + K+D + +KQ L+ + LE+ + K K+L + I+ + ++V+
Sbjct: 11870 TE--ETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 11927
Query: 1430 -ELQEDLNKESKEKQD------LEKRVLELTSKLE 1513
+ +EDL KE + K+D + +LE+ +K E
Sbjct: 11928 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAE 11962
Score = 78.6 bits (192), Expect = 1e-11
Identities = 115/572 (20%), Positives = 245/572 (42%), Gaps = 91/572 (15%)
Frame = +2
Query: 56 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 193
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 6314 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 6373
Query: 194 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 331
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6374 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 6433
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 499
N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 6434 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6490
Query: 500 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 676
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6491 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6550
Query: 677 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 808
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6551 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 6610
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 988
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 6611 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 6670
Query: 989 IERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
+ E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 6671 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 6728
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 1294
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6729 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 6788
Query: 1295 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 1420
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 6789 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 6844
Query: 1421 EVTELQEDLNKESKE------KQDLEKRVLEL 1498
E+ + + L K SKE K + EK+ ++L
Sbjct: 6845 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 6876
Score = 77.8 bits (190), Expect = 2e-11
Identities = 108/524 (20%), Positives = 230/524 (43%), Gaps = 31/524 (5%)
Frame = +2
Query: 38 TIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL---NDELERKKDD 208
T+ + L EK++ K I + K+ LE D++ L D LE++K+D
Sbjct: 10459 TLKEMEAHLEKEKEEMKSITEETR---RQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKED 10515
Query: 209 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILIL 388
N + L +RI + A ++ +ED I + + +
Sbjct: 10516 INHEWTQ-LQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDI 10574
Query: 389 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE--VLERS 562
+E +KE++++ +K E + ++ I S L+ + RS +H ++ D+ ++E+
Sbjct: 10575 KKEKEKEEEEEEMRVK----VEMDGKELDRIKSELK-RERSEIDHEQKKLNDDKKIIEQE 10629
Query: 563 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE 742
NL MK+ ++ ++ ++ +S L + EK +E + + ++ + HE
Sbjct: 10630 KQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEI 10689
Query: 743 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 922
+ +KE++D E+Q + D + + LQ + +R+ + ++K
Sbjct: 10690 QFQKEELD------------IERQ----KIADEQDLLIQNKSELQNENERIRNLNEIIKK 10733
Query: 923 RCSDLEAKNASLTDNQEGHEAEIE--RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAE 1096
L+ A L +E ++ E R+L+ + +++K+ D +MN D ++ E
Sbjct: 10734 ERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKD---LMNQRDLLEQE 10790
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IH 1270
R+ + K +LQQ++D+ +A ++++ + K+ G+++ LE T +
Sbjct: 10791 REEINHKWK-----------QLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 10839
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL------------------ 1396
IEMKT + + + EK+ + E EE I ++ + +K L
Sbjct: 10840 VIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQ 10899
Query: 1397 KDINIWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEK 1516
K +N ++ + + +EDL K K++Q +E+ EL +K+++
Sbjct: 10900 KKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQ 10943
Score = 76.6 bits (187), Expect = 4e-11
Identities = 112/520 (21%), Positives = 215/520 (41%), Gaps = 22/520 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA------- 166
+EN F+ IA L + K DK+ I N+ L+ +Q E + + +
Sbjct: 14610 IENITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYD 14669
Query: 167 -----KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 331
KT L D E+KK D ++ +K ++D AD+ + D E + L
Sbjct: 14670 EKVTYKTELEDSKEKKKPDRDSSLK------LTD--ADSAKTDGEREAQTL--------- 14712
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
V L EEL E ++K +I +L A+ + + L+ + RS
Sbjct: 14713 --ETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAK-------KDLQKLKEECRS 14763
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KT 688
+E + E LER ++L E+++ E + +++ + E Q +E K
Sbjct: 14764 AEEE--KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKM 14813
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPS--- 859
++ R+ + ++ ++ +T+ E + K+ + TV LE T+ S
Sbjct: 14814 QIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQ 14873
Query: 860 -LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDEL 1036
+ D+L ++++ V K ++ LE + + E E +E +E + + ++L
Sbjct: 14874 EMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKL 14932
Query: 1037 HKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER 1204
+ DKE + N LD ++ + K++ +ETT + +
Sbjct: 14933 LQLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETTIVLMKKD--------------- 14977
Query: 1205 DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDK 1381
K+ +E +L L+ T + E++ G DD NE EK K +ELE+ +
Sbjct: 14978 ------KENIENELLQLKQTEQEREIQRGTDDTSNEREKYDEKVTYKTELED-----NKE 15026
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
KK +D ++ L++ + D +E++ + + VL+LT
Sbjct: 15027 KKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 15066
Score = 76.3 bits (186), Expect = 5e-11
Identities = 125/547 (22%), Positives = 241/547 (44%), Gaps = 47/547 (8%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT---TLNDE 187
K+AD + + EL NE + I N I++ ++ L+ A LE K ++++E
Sbjct: 10702 KIADEQDLLIQNKSELQNENER---IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEE 10758
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R K+D L+K +D+ +D + + L +
Sbjct: 10759 TRRLKED--------LEKMSTDVNKQ--NKDLMNQRDLLEQEREEINHKWKQLQQRIDEF 10808
Query: 368 EVNILILHEE-LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES---KSRSLKEHFLRE 535
+ + E+ L KEK K +D + E K V E+ + E K KE+ E
Sbjct: 10809 DAQVSKQKEQDLPKEKGMK----EDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEE 10864
Query: 536 EEDE----VLERSASNLAIMKAIREEELRKEKDGKSA-LVENGEGCEAEKQGLEKTV--- 691
EE+E ++E L +K+ E +R E D + L + + E EK+ LEK
Sbjct: 10865 EEEEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEI 10923
Query: 692 ------LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDL 841
+E S LD + I + L K ++KS E E+Q + K LD+
Sbjct: 10924 MKQRQQMEEERSELD--NKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDI 10981
Query: 842 E-PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNL 1018
E I + L ++ ++ E + ++K +++ + +L E EI K E L
Sbjct: 10982 ERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETL------REMEIHLKKEKEEL 11035
Query: 1019 THN-DELHKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 1183
+E + K+D E + D++ H+K +R +LE + ++ + +LQQ++D+
Sbjct: 11036 RSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT----QLQQRIDEF 11091
Query: 1184 EAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDIEMKTGKDDDYN-----EA 1315
+A +++ + +E ++ LE+ R+++++ A + +I + ++D+ E
Sbjct: 11092 DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVEM 11151
Query: 1316 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 1495
E++ L + SEL+ S + + KKL D I E +L++ ++ ++Q +E+ E
Sbjct: 11152 EREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSE 11211
Query: 1496 LTSKLEK 1516
L +K+++
Sbjct: 11212 LDNKIKQ 11218
Score = 75.9 bits (185), Expect = 7e-11
Identities = 111/513 (21%), Positives = 213/513 (41%), Gaps = 67/513 (13%)
Frame = +2
Query: 179 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXI 355
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 535
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 536 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 682
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 683 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 805
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 806 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 928
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 929 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAE 1096
DL+ + A + +E E+E+ + N D E K E D K ++ + ++++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 1276
R+++E + +E L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 1277 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 1417
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 1418 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 75.5 bits (184), Expect = 9e-11
Identities = 110/522 (21%), Positives = 225/522 (43%), Gaps = 35/522 (6%)
Frame = +2
Query: 5 ALENKVADFE---ATIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEA 163
A + + DFE I N EL ++++ K + + R LE + + +V +
Sbjct: 7055 AFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITN 7114
Query: 164 AKTTLND---ELERKKDD-----------NNAIIKKA--LDKRISDLKADAPQRDQEDDM 295
+L+ EL + ++D N I+ + LD+R SD+ D Q++ +D M
Sbjct: 7115 ENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQKEVDDLM 7172
Query: 296 NALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVN 475
+ ++N+E L + + + K D +L + A E + +N
Sbjct: 7173 D--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLN 7218
Query: 476 EIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E +E + L ++ ++D++ ++R NL + K + E ++ + K +L
Sbjct: 7219 EEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAI 7278
Query: 653 GCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ 814
G + +EK E+ ++E A+ LD + E + +E++D++ +
Sbjct: 7279 GFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLF 7338
Query: 815 GPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 994
EKT DL+ T +N D + + ++ L K E E
Sbjct: 7339 QEEKT--DLQKTKEEIN----YDREEIYRQRTELNK-------------------EKETL 7373
Query: 995 RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKM 1174
+++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + + E +
Sbjct: 7374 KQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELA 7430
Query: 1175 DDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ---TLKKRIS 1345
D E NE+D L+ ++ ++K + +L+ E + + N+ +Q +K +
Sbjct: 7431 RDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTEEIKLKND 7484
Query: 1346 ELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 1465
L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7485 SLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7526
Score = 75.5 bits (184), Expect = 9e-11
Identities = 105/540 (19%), Positives = 219/540 (40%), Gaps = 57/540 (10%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 13268 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13317
Query: 221 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEV 373
+ AL+K + DL+ + +++NAL+ E
Sbjct: 13318 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 13358
Query: 374 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 532
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 13359 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 13417
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 13418 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13471
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 892
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13472 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13531
Query: 893 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1042
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13532 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13590
Query: 1043 EKDDKESIMNDL----------------------------DHVKAERQVLESKVSDMETT 1138
EKD E I DL D + + + L S +D+E
Sbjct: 13591 EKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQ 13650
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 13651 AKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDLT 13692
Query: 1319 KQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL ++
Sbjct: 13693 LQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQL 13752
Score = 74.3 bits (181), Expect = 2e-10
Identities = 104/548 (18%), Positives = 241/548 (43%), Gaps = 47/548 (8%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
++++ + I L EL EK+ I+ DR+ L+ K ++L+ +T +ND +
Sbjct: 3750 QDELDQLKTEIQNLQQELEKEKE---IIMKDRS-------ELDLKQSELDKQQTNMNDII 3799
Query: 191 ERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLE 370
E K++ + K + + + + D + N+L + +
Sbjct: 3800 ETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSL-------------------DED 3840
Query: 371 VNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKSRSLKEHFLREEED- 544
+ ++ L +++ +E+ +K +K + E G+ R + E + + + E RE+E
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 545 ----EVLERSASNLAIMKAIREE---ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 703
E ++ L +K E EL+KEK + EN + E +K L R
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK-QTEDVKNKKENLRLR 3959
Query: 704 ASNLDTMDA-IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DA 871
L + A IH+++ EK +KS + E+E+ K V DL+ I SL+ ++
Sbjct: 3960 EDELGQLQAEIHKQQREIEK-EKSNI-------ESERAAIIKIVEDLQHKIISLDRDAES 4011
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDN--QEGHEAEIERKLEASNLTHNDELH-- 1039
L+ D + E++ L++ ++LE + + + H+ + ++ A D+++
Sbjct: 4012 LKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINNL 4071
Query: 1040 -KEKDDKESIMND--------LDHVKAERQVLESKVSDMETTYSTL---NNELQQKMDDN 1183
+E + K+ ++N+ + +++++ +LE + ++E T S L +L+++ ++
Sbjct: 4072 IEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENT 4131
Query: 1184 EAFLN-ERDGLEAVKQGL-----------------EKRVLDLEATIHDIEMKTGKDDDYN 1309
A + ER+ LE + + + + + L+ I +++ + K+ +
Sbjct: 4132 LAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEII 4191
Query: 1310 EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
++ L R SEL++ + + D + + + + + E++E + KE+ ++++ +
Sbjct: 4192 MKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQSI 4251
Query: 1490 LELTSKLE 1513
L L+
Sbjct: 4252 KSLDEDLK 4259
Score = 74.3 bits (181), Expect = 2e-10
Identities = 122/611 (19%), Positives = 247/611 (40%), Gaps = 64/611 (10%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELER 196
+V + L E+ ++ K ++++ I ++ Q L + + L E+E
Sbjct: 8657 EVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIEN 8716
Query: 197 KKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVN 376
K D K L+K ++L + Q+++E L ++E++
Sbjct: 8717 TKRD-----KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEIS 8769
Query: 377 ILILHEEL-----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES-------- 499
++ E+ QK K++ + ++L+ + +N V HL
Sbjct: 8770 RELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQ 8829
Query: 500 --KSRSLKEHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDG 625
K ++ EH E + +++LE+ L +++I E L+K +D
Sbjct: 8830 YIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED- 8888
Query: 626 KSALVENGEGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGE 793
+ + E EKQ E + L+R+ +++ I E++ K K+D E
Sbjct: 8889 ---MEKEKENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSA 8944
Query: 794 GCEAEKQGPEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEA 943
E E + E DLE SLNDA LQ+ + + EK+ +E+ ++
Sbjct: 8945 AFEKEHKRLENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKT 9004
Query: 944 KNASLTDNQE-----------GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD-HV 1087
+ + +E GHE ++++K E + D+L ++ + + + DL +
Sbjct: 9005 ERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKL 9058
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 1267
+ +RQ +E ++MET +L+ ++ DD N+RD E LE + +L
Sbjct: 9059 QMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRET 9118
Query: 1268 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 1447
D+E K + + +E K+ ++ + LE + K + K++ SE +L
Sbjct: 9119 EDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQ 9178
Query: 1448 NKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGF 1624
++ +LE RV +E L++ + + E MS+ + + + L++
Sbjct: 9179 GALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEEL 9235
Query: 1625 SRKTSPLDITK 1657
R+ L+I+K
Sbjct: 9236 QREKEQLEISK 9246
Score = 73.6 bits (179), Expect = 3e-10
Identities = 109/526 (20%), Positives = 232/526 (44%), Gaps = 23/526 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N+ D E + + DE N + K+ + +DR+ LE + DLE KT + +
Sbjct: 3046 LQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKER-------FDLEKTKTEMGN- 3097
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
+KK L+ +I + + +E + I+ L
Sbjct: 3098 -----------LKKQLESQIRQHEIQLVEIQKERE--------------------ILEQL 3126
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKSRSLKEHFLREEED 544
++N+ E+L+KE+D D+ +E K ++ E + + ++ +++E D
Sbjct: 3127 KINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTR--------IKQEMD 3178
Query: 545 EVLERSASNLA-------IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 703
E LE++ NLA + K I E+E K + K+ L + E + E Q E+ LE
Sbjct: 3179 E-LEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQN-ERQNLEEA 3236
Query: 704 ASNL----DTMDAIHEEELRKEKVDKSALTE---NGEGCEAEKQGPEKTVLDLEPTIPSL 862
+ L + ++++ EE RK+ V ++ E + E+ KQ E+ +++L+ T+ +
Sbjct: 3237 GTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTVTDI 3296
Query: 863 NDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHK 1042
A + ++++ E++ + + ++++A+ L ++G E++++ N T L +
Sbjct: 3297 AGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGIS---EQQVDIVNKTEQLRLRE 3353
Query: 1043 EKDD--KESIMNDLDHVKAERQVL---ESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
+ + + I D ++A R+ + + ++ +T L E+ Q M+ +D
Sbjct: 3354 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMME-----YASKD 3408
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAK 1387
+ LEK ++ A H ++++ K+ E Q L E+++ + L + K
Sbjct: 3409 -----RANLEKEKSEMIAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMK 3463
Query: 1388 KLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
+L E +LQ+ +L +E+ + + L+++ LEK
Sbjct: 3464 ELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEK 3509
Score = 72.8 bits (177), Expect = 6e-10
Identities = 117/569 (20%), Positives = 233/569 (40%), Gaps = 66/569 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAK 169
Q+ + + + + T+ L DE +++ + N+ ++ K +LE ADL+
Sbjct: 13547 QSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRKA 13606
Query: 170 TTLNDELERKKDDNNAIIKKAL--------DKRISDLKADAPQRDQ--EDDMNALIXXXX 319
L++E+ + + I + A ++ + ++AD ++ + E D+ L
Sbjct: 13607 EKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKE 13666
Query: 320 XXXXXXXXXXXIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 487
+ +LE N L L +EL+KEK +I D+ + + V+
Sbjct: 13667 ILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------DAVA 13718
Query: 488 HLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 13719 SLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR 13777
Query: 662 AEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTENGE 793
+ + ++ + E R D + DA+ + +EL K D E+ E
Sbjct: 13778 NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVE 13837
Query: 794 GCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA------- 943
E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 13838 KEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKT 13897
Query: 944 -----KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH--- 1084
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 13898 LVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEV 13957
Query: 1085 ------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGLEKR 1243
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +E
Sbjct: 13958 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE-- 14015
Query: 1244 VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 1423
+EKQ++++ +EL K+L +++ + E
Sbjct: 14016 -----------------------SEKQSIERERAEL-----------KRLKEEVEVQ-HE 14040
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKL 1510
T LQ+D N KEK+ LE T ++
Sbjct: 14041 RTLLQQDKNMIQKEKEHLEGEKARTTEEI 14069
Score = 71.6 bits (174), Expect = 1e-09
Identities = 107/531 (20%), Positives = 221/531 (41%), Gaps = 28/531 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
++ ++ + E T + EL N + K+ I ++R+ +E K L+ + D E + + ++
Sbjct: 2779 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2838
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++++ +IK +K+ + D + +
Sbjct: 2839 ---RRNNEEMVIKLQNEKKDIETSTDR-----------------------------IRDE 2866
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEED 544
E N+ +L + L+ ++D L K+ + + ++ LES++R + ++E
Sbjct: 2867 EANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKER 2923
Query: 545 EVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
E+LE+ L+ K E+E KEK S E E ++E++G+ KT R
Sbjct: 2924 EILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIK 2977
Query: 716 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 895
MD EL++ +++ EN E +KQ ++ + D++
Sbjct: 2978 KEMD-----ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKI 3011
Query: 896 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDK 1057
K L+K D E + + ++ +E + ++ +E S DE + K
Sbjct: 3012 EQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQK 3071
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
+ + +D D ++ ER LE ++M L ++++Q ER+ LE +K L
Sbjct: 3072 QRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLS 3131
Query: 1238 KRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL---- 1372
K+ DLE E + +D ++E++ +K+ + ELE+ L
Sbjct: 3132 KQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQ 3191
Query: 1373 --TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3192 ENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 71.6 bits (174), Expect = 1e-09
Identities = 111/536 (20%), Positives = 234/536 (43%), Gaps = 60/536 (11%)
Frame = +2
Query: 86 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERK-KDDNNAIIKKALDKRISD 253
K + NDRN++E + LE ++L + + DE L++K K+ N K +K I +
Sbjct: 10048 KKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVE 10107
Query: 254 LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKE----KDDK 421
+ A +Q +D +++ E + E+++ K+++
Sbjct: 10108 -RLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNER 10166
Query: 422 TALIKDLVAAEPGKRTVNEIVSHLESKSRSL----------------KEHFLREEEDEV- 550
L + + K+ + I+ + L K+ L +E +E+
Sbjct: 10167 ETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEIN 10226
Query: 551 ------LERSASNLAIMKAIREEELRKEK---DGKSALVE-NGEGCEAE-KQGLEKTVLE 697
+R A ++ +EE+L +K + + L E NG+ E + K LE +
Sbjct: 10227 HKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEIN 10286
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT-IPSLNDAL 874
++ L T+ +E++ KEK A+T + E E K+ L E T + L
Sbjct: 10287 QKIEELQTL----QEQIMKEKEKAEAMTIKLK-MEREDLDQIKSELVREKTEVDHEQKKL 10341
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
D+ + EK+ LEK S++ + + E +E++ K++ ++L +D + K K+
Sbjct: 10342 NDDIKMIEQEKEDLEKMKSEIMTQKQEM----EKERSELDNKIQQTDLEKHD-IEKSKEI 10396
Query: 1055 KESIMNDLDHVKAERQVLES-------KVSDMETTY----STLNNELQQKMDDNEAFLNE 1201
E +M +++ + E Q+ + K++D + S L NE ++ + NE E
Sbjct: 10397 VEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKE 10456
Query: 1202 RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------DYNEAEKQTLKKR--ISELEE 1357
R+ L+ ++ LEK ++++ E + K+D D E + +K+R + + +E
Sbjct: 10457 RETLKEMEAHLEKEKEEMKSITE--ETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKE 10514
Query: 1358 AISILTDKAKKLLKDINIWLSEVTE----LQEDLNKESKEKQDLEKRVLELTSKLE 1513
I+ + ++ + + + +S+ E Q+++ +E K ++ + R++E+ +K E
Sbjct: 10515 DINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAE 10570
Score = 71.6 bits (174), Expect = 1e-09
Identities = 109/563 (19%), Positives = 243/563 (43%), Gaps = 50/563 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LER 196
D E+ L++E +D+ K + +N+L +K + +LE T + E +E+
Sbjct: 13779 DLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEK 13838
Query: 197 KKDD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXX 346
++++ N IIK ++L+ I K + A +R Q + + L
Sbjct: 13839 EREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTL 13898
Query: 347 XXIVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
+ + + L LQK+K++ L ++ + AE K V L+ + +
Sbjct: 13899 VQTEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQK 13955
Query: 509 SLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----E 661
+++ + + E +VLE+ S L + + E++++E++ L+E E C E
Sbjct: 13956 EVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE 14015
Query: 662 AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
+EKQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L
Sbjct: 14016 SEKQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNL 14072
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQ 970
+ I + L + A++Q E K+ D+ E TD
Sbjct: 14073 KEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDAS 14132
Query: 971 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL----ESKVSDMETT 1138
+ + + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 14133 QKFQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEM 14191
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
LNNE+++ E+D L+ K ++ ++ + E + + + +++
Sbjct: 14192 RDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE------ 14245
Query: 1319 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 1498
+ L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 14246 -EKLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQL 14304
Query: 1499 TS-KLEKCICGARDGLSTIKEAW 1564
+ E+ I D ST KE +
Sbjct: 14305 KQIEQEREIQRKADVTSTEKEMY 14327
Score = 70.9 bits (172), Expect = 2e-09
Identities = 120/625 (19%), Positives = 268/625 (42%), Gaps = 75/625 (12%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNE----KDDKKCIVNDR-NILEAAKQALEYKVADLEAAKT 172
L+ ++ +F+A ++ ++ L + K+D+K + + N++E +A + +++ K
Sbjct: 10801 LQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKA---EPEEIKKEKE 10857
Query: 173 TLNDELERKKDDNNAII---KKALDKRISDLKADAPQRDQE----DDMNALIXXXXXXXX 331
N+E E ++++ I+ +K L + S+L+ + D E +D +I
Sbjct: 10858 KENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKED-- 10915
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
+ ++ I+ +++++E+ + I+ + H KS+
Sbjct: 10916 --------LEKMKSEIMKQRQQMEEERSELDNKIQQ-----------TNLEKHDIEKSKE 10956
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV 691
+ E + E E++ ++ + K + E +K D ++ LV+N + E + ++K V
Sbjct: 10957 IVEKLMVEVEEQ-----RKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKK-V 11010
Query: 692 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
E +T+ + E L+KEK + ++ E + + + + + + + + + D
Sbjct: 11011 DEEIKKERETLREM-EIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDL 11069
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK---------LEASNLTH 1024
L+++ + + E L++R + +A+ + ++ E E ERK +E
Sbjct: 11070 LEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAE 11129
Query: 1025 NDELHKEKDDK-ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE 1201
E+ +EK+++ E M + V+ ER+ L S+++ S +++E ++ DD + E
Sbjct: 11130 LQEIMQEKEEEDEEEMRVI--VEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQE 11187
Query: 1202 RDGLEAVK-------QGLEKRVLDLEATI-------HDIE-------------------M 1282
++ LE +K Q +E+ +L+ I HDIE +
Sbjct: 11188 KEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDI 11247
Query: 1283 KTGKDD---------------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 1417
+ K++ N+A+ Q +RI E++E I K K+ LK++ L
Sbjct: 11248 RLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHL 11303
Query: 1418 SEVTELQEDLNKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 1591
+ E + +E+ ++K+DLEK ++ +K + + RD L +E +
Sbjct: 11304 RKEKEEMRSVIEETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHK 11356
Query: 1592 WVPFEDLVQGFSRKTSPL---DITK 1657
W + + F + S D+TK
Sbjct: 11357 WTQLQQRIDEFDAQVSKQKEEDLTK 11381
Score = 70.5 bits (171), Expect = 3e-09
Identities = 111/536 (20%), Positives = 225/536 (41%), Gaps = 32/536 (5%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + + + +I +L+++L K K+ I ++N LE K L+ + ++ K
Sbjct: 4238 QEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQ 4297
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXXXXXI 355
+E + + A+IK+ D + L A+ +R++E D+M I
Sbjct: 4298 NERQSLEKMTKALIKERED--LVHL-AEYTKREKEMLDEMQVA---NKSSMADLQREKRI 4351
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 535
+ + NI E+++ EK+ +L + + + ++ S + +RE
Sbjct: 4352 LEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIRE 4411
Query: 536 EEDEV--LERSASNLAI-MKAIREEELRKEKDGK-------------SALVENGEGCEAE 667
+++ + L++ + ++ I MK I E+ E D ++ + E + +
Sbjct: 4412 KQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLD 4471
Query: 668 KQ--GLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
++ G EK VL++ ++L I +E+ K K++ + E+Q E+ D
Sbjct: 4472 REAFGNEKEVLKQMKTDLQ----IQADEIEKIKLET----------QHERQRVEEMTADF 4517
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDN------QEGHEAEIERKL 1003
T+ + L ++ + + +KQ +EK D++ SL N Q+ E + KL
Sbjct: 4518 METMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKL 4577
Query: 1004 EASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 1183
E + EL KE D+ I + + ERQ LE +++ + + + +
Sbjct: 4578 EQMKI----ELEKEADEIRKIKEETQN---ERQRLEKMTEELKKEKESFTHLAEDTKTEK 4630
Query: 1184 EAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAI 1363
+ + E++ L+K +LE +I +T + +E EK+ ++ R ELE+
Sbjct: 4631 KILDKMKVANESLMADLQKEKSNLEEMRENISKQT----EDSEKEKEKIRLREDELEQ-- 4684
Query: 1364 SILTDKAKKLLKDINIWLSEVTELQEDLNKES------KEKQDLEKRVLELTSKLE 1513
L +I+ E+ E N ES K+ +DL+ ++ L LE
Sbjct: 4685 ---------LQAEIHKQQGEIK--MEKSNNESERAAIIKDVKDLQHKMFSLDRDLE 4729
Score = 69.3 bits (168), Expect = 7e-09
Identities = 116/533 (21%), Positives = 226/533 (42%), Gaps = 17/533 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ +E KQ +E + +++ ++ +L+++
Sbjct: 5331 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 5390
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++ K + K+ ++ + L+ + ++E D + I N
Sbjct: 5391 QKKMK-----LQKQMFEEEKNKLEQMKIELEREADEISKIKEE-------------TQNK 5432
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
+ + EEL +EK+ L +D + K+ ++E+ ES L + E
Sbjct: 5433 RQRLEKMTEELIREKESLAHLAED---TKTEKKILDEMKVANESSMADL------QREKS 5483
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSAL--VENGEGCEAEKQGLEKTVLERRASNLDT 721
+LE N++ +K + E K K + L ++ + K +EKT +E + +
Sbjct: 5484 ILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIR 5543
Query: 722 MDAIHEEELRKEKVD-----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
EL+K+ D K LTE E + D+E L D L+RD
Sbjct: 5544 EKQNMMTELKKKSEDVEIQMKEILTEK----ELLHNDRKLLTRDVENLQQKLID-LERDS 5598
Query: 887 DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDE-----LHKEK 1048
R+ +++A E ++ EA TD Q + EIE+ KLE + E + KE+
Sbjct: 5599 KRLKLDREAFE---NEKEAMKQMKTDLQIQAD-EIEKIKLETQHDRQRVEEMAAQIQKER 5654
Query: 1049 DDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 1228
D I N ++ + VL K D+E ++ ++ + R L VK+
Sbjct: 5655 D---KINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKE 5711
Query: 1229 GLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDIN 1408
LEK+ E T+ +I+ + + NE + + + I EE ++ D+ +L
Sbjct: 5712 DLEKQ---KENTLAEIQKEREDVEKMNENITREMHE-IKHQEEQMNQKQDELDQL----- 5762
Query: 1409 IWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEKCICGARDGLSTIK 1555
+E+ LQ++L KE K++ + R S+L+K D + T+K
Sbjct: 5763 --KTEIQNLQQELEKEKEIIMKDRSQFDLR----QSELDKQQTNMNDIMETMK 5809
Score = 68.9 bits (167), Expect = 9e-09
Identities = 117/544 (21%), Positives = 231/544 (42%), Gaps = 39/544 (7%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDD--------KKCIVNDRNILEAAKQALEYKVADL 157
Q AD E + EL KD+ +K V+ + + +++ E +L
Sbjct: 1711 QTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIEL 1770
Query: 158 EAAKTTLN---DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 328
E A+ LN ++E +K A +K L K +L+A ++ ED+ AL
Sbjct: 1771 EKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ--RKMMEDEKRALENMKYELQ 1828
Query: 329 XXXXXXXXIVSNLEVNILILH----------EELQKEKDDKTAL-------IKDLVAAEP 457
N+ + EEL+K++ D L IKDL
Sbjct: 1829 RESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDL----E 1884
Query: 458 GKRTVNEI-VSHLESKSRSLKE-HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 631
R +NE+ ++ +++KS L++ L ++ + +E S + I RE +L++ + +
Sbjct: 1885 NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKI----REYDLQQMQTDLN 1940
Query: 632 ALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG-EGCEAE 808
+ E Q ++ V ++ + D I E+ K+ D T+N + + E
Sbjct: 1941 RQ-------QKEMQDIQNAVFMEKSELKKSQDEIAEQ--LKQVGDMMQFTQNEKDNLDRE 1991
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRV-MAEKQALEKRCSDLEAKNASLTDNQEGHEA 985
+ + L +E + L L R+L+ + + +K+ L ++ + + + + D Q+ +
Sbjct: 1992 RAAIIEQKLQMERDMTHL---LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQM 2048
Query: 986 EI--ERKLEASNLTHNDELHKEKDDKESIMNDL--DHVKAERQVLESKVSDMETTYSTLN 1153
+I ER+ E L + +EKD ES++ L D K L K +E L
Sbjct: 2049 KINLEREKEEMQL-QRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK-QKLEDAAVELQ 2106
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 1333
E + M+ E +R+ ++ ++ G+EK+ E T D++ K+ E ++Q ++
Sbjct: 2107 KERDEIMNIAEETKRKREDVDKIRVGIEKQ----EITFKDLKADLQKEAAIVENQRQAVQ 2162
Query: 1334 K---RISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
K + ++E I +L+++I + E+Q +++KE +E + + + TS
Sbjct: 2163 KDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETS 2222
Query: 1505 KLEK 1516
KL +
Sbjct: 2223 KLRE 2226
Score = 68.9 bits (167), Expect = 9e-09
Identities = 104/526 (19%), Positives = 213/526 (40%), Gaps = 32/526 (6%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKC----IVNDRNILEAAKQALEYKVADL------ 157
L+ V D L ++LL E++ K I ++++L KQ + + D+
Sbjct: 3289 LKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQ 3348
Query: 158 ----EAAKTTLNDELERKKDDNNAIIKKALDK--RISDLKADAPQRDQEDDMNALIXXXX 319
E L + R++D+ A K +++ R+ K + + +E +
Sbjct: 3349 LRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKD 3408
Query: 320 XXXXXXXXXXXIVSNLEVNILILHEELQKEK---DDKTALIKDLVAAEPGKRTVNEIVSH 490
I +++I EL KE+ +++T ++ KRT E+
Sbjct: 3409 RANLEKEKSEMIAQKHQMDI-----ELNKERGLIEERTQMLNTYEKEMDQKRTALEV--- 3460
Query: 491 LESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E K + ++EE++++ L+R A ++ +K E+ R E+ + EN
Sbjct: 3461 -EMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLK----EKTRNERQSLEKMAEN-- 3513
Query: 653 GCEAEKQGLEKTVLERRASNLDTMDAIHEE---ELRKEKVDKSALTEN----GEGCEAEK 811
E EK L + + + D M +HE +++KEK + + E+ E ++EK
Sbjct: 3514 -LEKEKDDLAHLAEDTKRKD-DEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEK 3571
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
K ++ E + + + R + +K +E + + KN L
Sbjct: 3572 ----KKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMT--------- 3618
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQK 1171
EL K+ +D E M + V E+++LES ++ L +L
Sbjct: 3619 -------------ELTKQSEDVEIQMKE---VLTEKELLESDRKLLKKDVENLQQKLLII 3662
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 1351
D+E+ +R+ LE K+ L++ DL+ +IE K + + + + +I +
Sbjct: 3663 ESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE-KIKLETQHERQRVEEMTAQIQKD 3721
Query: 1352 EEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
E + + D + + DI ++ + Q++L++ E Q+L++ +
Sbjct: 3722 REYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQEL 3767
Score = 68.6 bits (166), Expect = 1e-08
Identities = 121/564 (21%), Positives = 227/564 (40%), Gaps = 64/564 (11%)
Frame = +2
Query: 17 KVADFEATIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 193
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 12933 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 12990
Query: 194 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 12991 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 13032
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 13033 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 13092
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 721
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 13093 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 13148
Query: 722 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 874
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 13149 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 13206
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKLEA 1009
+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 13207 EESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRERE 13266
Query: 1010 SNLTHNDELHKEKDD----KESIMNDLDHV----------KAERQVLESKVSDMETTYST 1147
D+L KEK+D KE I + +H+ K E + K+ M+T
Sbjct: 13267 EIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQV 13326
Query: 1148 LNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATIHD 1273
N L++ M D + ER+ + A+ K+ ++ +L +++ D
Sbjct: 13327 KTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 13383
Query: 1274 IE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 1444
IE +K + N+ +K LK R ELE I KK K+ ++ E+Q +
Sbjct: 13384 IESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQRE 13433
Query: 1445 LNKESKEKQDLEKRVLELTSKLEK 1516
K +LE++ EL +K+EK
Sbjct: 13434 RKALEKMNAELERKSTELKNKIEK 13457
Score = 65.9 bits (159), Expect = 7e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = +2
Query: 461 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 637
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 638 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 817
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 818 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 998 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 1126
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 1127 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 1303
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 1304 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 1462
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 1463 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 1627
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 1628 RKTSPLDITKT-----CDAVDISEDST 1693
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 1e-07
Identities = 118/608 (19%), Positives = 236/608 (38%), Gaps = 108/608 (17%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKT 172
++ D E + LN+ LN+ K ++ ++ +E K ++ + DL+ +T
Sbjct: 1879 EIKDLE-NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1937
Query: 173 TLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 346
LN + + +D NA+ K L K ++ A Q Q DM
Sbjct: 1938 DLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK--------- 1985
Query: 347 XXIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
NL+ I+ ++LQ E+D L ++L + + K+ V LE SL
Sbjct: 1986 ----DNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRD 2041
Query: 524 FLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKT 688
E+ ++ LER + + + EE K + L E+ E AEKQ LE
Sbjct: 2042 MQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDA 2101
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDK----------------------SALTENGEGC- 799
+E + + M+ E + ++E VDK +A+ EN
Sbjct: 2102 AVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAV 2161
Query: 800 --------------EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 937
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +L
Sbjct: 2162 QKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDEL 2217
Query: 938 EAKNASLTDNQEGHEAEIER----KLEASNLTHNDELHKEKDDKESIMNDLD-------- 1081
E + + L ++++ + E+ + E + N EL E KE + +L+
Sbjct: 2218 EQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRE 2277
Query: 1082 -------------------------HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
++A++ K ++T L+++ + E
Sbjct: 2278 NEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEME 2337
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKK 1336
+ E + +E K+ + ++ E+ + +EM+ Y E ++Q +K
Sbjct: 2338 SLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEK 2397
Query: 1337 RISELEEAISILTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVL 1492
I ++ + I + ++ K++ I V E Q+ + ++SK E ++ K++
Sbjct: 2398 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKIN 2457
Query: 1493 ELTSKLEK 1516
S++EK
Sbjct: 2458 ADLSEVEK 2465
Score = 63.9 bits (154), Expect = 3e-07
Identities = 103/563 (18%), Positives = 240/563 (42%), Gaps = 74/563 (13%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 226
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 10937 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 10996
Query: 227 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIV 358
K +D+ I + + + +++++ ++I +
Sbjct: 10997 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 11056
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 538
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 11057 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 11109
Query: 539 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 700
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 11110 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 11165
Query: 701 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 838
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 11166 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 11220
Query: 839 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1015
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 11221 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 11279
Query: 1016 LTHNDELHKEKDDKESIMNDLDHVKAERQVLES--------KVSDMETTYSTLNNELQQK 1171
+ + K +KE++ H++ E++ + S K D+E + +N + Q
Sbjct: 11280 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 11339
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 1330
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 11340 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 11399
Query: 1331 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 1459
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 11400 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11459
Query: 1460 K----EKQDLEKRVLELTSKLEK 1516
K EK+DLEK E+ + ++
Sbjct: 11460 KMIEQEKEDLEKMKSEIMKQRQQ 11482
Score = 63.9 bits (154), Expect = 3e-07
Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 16/514 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALE-YKVADLEAA------ 166
+EN F IA L ++ K DK+ I N+ L+ +Q E + AD+ +
Sbjct: 14269 IENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKADVTSTEKEMYT 14328
Query: 167 -KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXX 343
K T ELE K+ IK D + D+ + D E + L
Sbjct: 14329 EKVTYKTELEDSKEK----IKPDRDSTLELTDTDSAKTDGEREAQTL-----------ET 14373
Query: 344 XXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
V L + EEL E ++K +I +L A+ + + L+ + RS +E
Sbjct: 14374 KVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAK-------KDLQKLKEECRSAEEE 14426
Query: 524 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLER 700
+ E LER ++L E+++ E + +++ + E Q +E K ++
Sbjct: 14427 --KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQT 14476
Query: 701 RASNLDTMDAIHEEELRKEKVDKSA-LTENGEGCEAEKQGPEKTVLDLEPTIPS-LNDAL 874
R+ + ++ +E ++ + +T+ E + K+ + V LE T+ S + +
Sbjct: 14477 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMR 14536
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
+++ V K ++ LE + + E E +E L+ + + + L + D
Sbjct: 14537 DMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKS-RNEETLLQLLHD 14595
Query: 1055 KESIMNDLDHVKAERQ----VLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAV 1222
K+ + N LD E + + ++ +ETT + + +
Sbjct: 14596 KDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKD--------------------- 14634
Query: 1223 KQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLK 1399
K+ +E +L L+ T + E++ G DD NE E K +ELE+ + + KK +
Sbjct: 14635 KENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELED-----SKEKKKPDR 14689
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
D ++ L++ + D +E++ + + VL+LT
Sbjct: 14690 DSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 14723
Score = 63.5 bits (153), Expect = 4e-07
Identities = 113/537 (21%), Positives = 220/537 (40%), Gaps = 46/537 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL--------- 178
+ E T NDE+ EK I + + +L + LE ADLE K +
Sbjct: 7999 NMEKTYEQQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLA 8055
Query: 179 -NDELERKKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXX 334
N+ LER+K D II+ +A +R ++ A A +RD E+ M +
Sbjct: 8056 ENELLEREKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQE 8114
Query: 335 XXXXXXI--------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH 490
+ + L+ ++L EL+K K D + DL ++T +EI+ H
Sbjct: 8115 ASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKH 8168
Query: 491 ---LESKSRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENG 649
+SK+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 8169 EKDTDSKTRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM---- 8223
Query: 650 EGCEAEKQGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEK 811
K V+ +R D M+ I EE+ +E+ + L N + +
Sbjct: 8224 -----------KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDF 8268
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ + +LE ++ D++R++ E + + +L+ E+
Sbjct: 8269 ELLLERTANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EM 8309
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTL 1150
ER++E S + DE K + + + D+ ++ L ++ ++E + L
Sbjct: 8310 ERRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAEL 8368
Query: 1151 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL 1330
+ Q++ E ER+ LE +K + + D+E +E K++ + Q
Sbjct: 8369 AEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKY 8428
Query: 1331 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 1498
K+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8429 KEELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8481
Score = 63.5 bits (153), Expect = 4e-07
Identities = 118/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = +2
Query: 2 QALENKVAD-FEATIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 172
Q LE KV D + T T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 14710 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 14769
Query: 173 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 274
+ + LER+++ + + L ++ +K + Q
Sbjct: 14770 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 14829
Query: 275 ----RDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDL 442
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 14830 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 14886
Query: 443 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 619
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 14887 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 14946
Query: 620 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 733
D K+ +EN E E E L++T ER T D
Sbjct: 14947 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 15005
Query: 734 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 910
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 15006 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 15053
Query: 911 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVK 1090
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 15054 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 15094
Query: 1091 AERQVLESKVSDMETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 1249
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 15095 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 15154
Query: 1250 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 1420
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 15155 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 15214
Query: 1421 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 1513
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 15215 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 15256
Score = 61.6 bits (148), Expect = 1e-06
Identities = 89/490 (18%), Positives = 194/490 (39%), Gaps = 3/490 (0%)
Frame = +2
Query: 98 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 277
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 278 DQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 457
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 458 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 637
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 638 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEK 811
+ E E ++ ++ +T R +L+ + ++E L + K L + E +K
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
D ++ + ++ + L++ +DL + + D Q E
Sbjct: 1916 ------------------DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFME- 1956
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAER-QVLESKVSDMETTYSTLNNELQQ 1168
+ +L+ S ++L + D + N+ D++ ER ++E K+ LN EL+
Sbjct: 1957 KSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELES 2016
Query: 1169 KMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISE 1348
+ LNE+ LE + L + + DLE +++ ++ + + ++Q++ + +
Sbjct: 2017 LKLVKKEVLNEKRLLEDCRISLMRDMQDLE----QMKINLEREKEEMQLQRQSIAEEKDK 2072
Query: 1349 LEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICG 1528
LE + L + +KL D ++ + +L KE E ++ + ++K G
Sbjct: 2073 LESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVG 2132
Query: 1529 ARDGLSTIKE 1558
T K+
Sbjct: 2133 IEKQEITFKD 2142
Score = 61.2 bits (147), Expect = 2e-06
Identities = 118/559 (21%), Positives = 227/559 (40%), Gaps = 54/559 (9%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--------- 160
LE A E L+ EL K+ I ++R LE K L+ K D+E
Sbjct: 7600 LEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYE 7659
Query: 161 ----AAKTTLNDELERKKDDNNAIIKKA------LDKRISDLKADAPQRDQEDD---MNA 301
A + + N +++ D+ NA ++K D+ + K + + E + A
Sbjct: 7660 KQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKARAETERVKQGA 7719
Query: 302 LIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIK--DLVAAEPGKRTVN 475
I + ++ N+ E ++K+K + + DL+ A+ K+
Sbjct: 7720 KIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEE 7779
Query: 476 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG 655
+ +ES+ +E + +E LE + + I + L+ E DGK V+N
Sbjct: 7780 MVKQKIESEREIQQEKKKLQRSEEELEDKMQKIK-REMIELKLLQDETDGKRKDVDN--- 7835
Query: 656 CEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL 835
+ + R+ L+ M A E +K +VD+ L + E K ++
Sbjct: 7836 --------KMRQVARKRDELEKMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE 7887
Query: 836 DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL--EAKNASLTDNQEGHEAEIERKLEA 1009
++ + A +R D + EK+ + R L EA+ AS HE E+ + E
Sbjct: 7888 HMQ------SHAEERAGD--LGEKEPVNTRIQRLIQEAEKASKMAWSTKHEPEMRMQREV 7939
Query: 1010 S----NLTHND----------ELHKEKDDKESIMNDLDHVKAERQVLE-------SKVSD 1126
S ++ D E+ ++ + +++ + ER LE + +
Sbjct: 7940 SVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKN 7999
Query: 1127 METTYSTLNNELQ---QKMDDNEAFLN-ERDGLEAVKQGLE--KRVLDLEATIHDIEMKT 1288
ME TY N+E+Q Q+++ ++ L+ ER+ LE + LE K+++ L+ + K
Sbjct: 8000 MEKTYEQQNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALD------KQKL 8053
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILT-DKAKKLLKDINIWLSEVTELQEDLNKESKE 1465
+++ E EK + K I LE T ++A + + E+ + E L+ E +
Sbjct: 8054 LAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQ 8113
Query: 1466 KQDLEKRVLELTSKLEKCI 1522
+ + +++EL +++K I
Sbjct: 8114 EAS-KNQMVELKRQIDKLI 8131
Score = 60.8 bits (146), Expect = 2e-06
Identities = 117/551 (21%), Positives = 209/551 (37%), Gaps = 81/551 (14%)
Frame = +2
Query: 56 DELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK---TTLNDELERKKDD--NN 214
++LL E +K+ ND + E K+ ALE + D+ K +L +E+ K+ + N
Sbjct: 13675 NDLLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNK 13734
Query: 215 AIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
K + DL+ R Q+ +++ I ++LE
Sbjct: 13735 ETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR----------NDLESMK 13784
Query: 380 LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK---EHFLREEEDEV 550
+L EE ++ +D+ P K + LE + +K EH +E E
Sbjct: 13785 TLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKERE--- 13841
Query: 551 LERSASNLAIMKAIRE--------EELRKEKDGKSALVENGEGCEAE----KQGLEKTVL 694
E N I+K+ E E ++E GK A +E+ E A+ ++ V
Sbjct: 13842 -EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 13900
Query: 695 ERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
+ ++ + E EL+ + K+ L E EAEK E + L+ + D
Sbjct: 13901 TEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDI 13960
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL---------------- 1003
+ + +E+ LEK S+L + L + + + E+ER L
Sbjct: 13961 MTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIES 14016
Query: 1004 ----------EASNLTHNDELHKEK----DDKESIMNDLDHVKAER-------QVLESKV 1120
E L E+ E+ DK I + +H++ E+ L+ ++
Sbjct: 14017 EKQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEI 14076
Query: 1121 SDMETTYSTLNNELQQKMDDNEAF-----LNERDGLEAVKQGLEKRVL-----------D 1252
+ LN E++ K + E + D L+ L + ++
Sbjct: 14077 KRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQ 14136
Query: 1253 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 1432
L+ T D E +T D+ +T ++R LEE ++ T K ++K + SEV E
Sbjct: 14137 LKTTSRDAETQTSLDE-----ITKTDERRQRALEETVA-TTAKQPIVIKLEDTLTSEVQE 14190
Query: 1433 LQEDLNKESKE 1465
+++ LN E KE
Sbjct: 14191 MRDHLNNEIKE 14201
Score = 60.5 bits (145), Expect = 3e-06
Identities = 112/543 (20%), Positives = 217/543 (39%), Gaps = 48/543 (8%)
Frame = +2
Query: 14 NKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN-DEL 190
+K+ + +A + EL K D K ++D LE + + D ++ L E+
Sbjct: 8128 DKLIELKADLLQQQTELKKTKADLKQQMDD---LEKTRSEILKHEKDTDSKTRELELIEI 8184
Query: 191 ERKKDDNNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXXIV 358
+R+KDD I+K L+KR + L+++ ++D + M +I
Sbjct: 8185 QRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANAT 8244
Query: 359 SNLE---VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSR 508
+ + IL +Q + D +TA ++D +A +R V E+V + R
Sbjct: 8245 EEINRERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVR 8303
Query: 509 SLK---EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQG 676
+LK E + + + E+ E+ I + I++ ++R+ G +E + E +
Sbjct: 8304 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 8363
Query: 677 LEKTVLERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT 829
+ + E++ + +H+E E+ +EK D E E +++ E T
Sbjct: 8364 MRAELAEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFT 8423
Query: 830 -VLDLEPTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
+ + + S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +
Sbjct: 8424 DIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-K 8482
Query: 998 KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 1177
K E DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8483 KGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDL 8542
Query: 1178 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------ 1339
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8543 FRSELQRQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKI 8599
Query: 1340 ----------ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
I + + IL D + +D + E +L E D+E+ V
Sbjct: 8600 RFDIANARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLV 8655
Query: 1490 LEL 1498
LE+
Sbjct: 8656 LEV 8658
>ref|XP_005159739.1| PREDICTED: titin isoform X2 [Danio rerio]
Length = 15734
Score = 101 bits (251), Expect = 2e-18
Identities = 132/600 (22%), Positives = 266/600 (44%), Gaps = 39/600 (6%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRN--------ILEAAKQALEYKVADL 157
Q +E A + +N+ L+ E + K ++N++N +++ K LE + DL
Sbjct: 6202 QRVEEMTAQIQKDRDKINN-LIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDL 6260
Query: 158 EAAKTTL---NDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXX 316
E ++ L ++LE++K++ A I+K L+K ++ + + + QE+ MN
Sbjct: 6261 EKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQ----- 6315
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKRTVNEIV 484
+ L+ I L +EL+KEK+ ++ L + + + +N+I+
Sbjct: 6316 ---------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIM 6366
Query: 485 SHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
++++ + L K+ EE+ + +E+ N+ + +E+L+ K K + E E
Sbjct: 6367 ETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLE 6426
Query: 662 AEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTENGEGCEAEKQGPEK 826
K LE+ + R +T + EEL+KE+ D + L E+ + EK ++
Sbjct: 6427 QMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED---TKREKNSLDE 6483
Query: 827 TVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLE 1006
+ E ++ L Q++ + K+ + K+ D+E + D E E+E+ L+
Sbjct: 6484 MKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DKIRLREDELEQ-LQ 6534
Query: 1007 ASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
A E+HK++ + E + +++ ER + V D+++ +L+ + + D E
Sbjct: 6535 A-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE 6584
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI 1342
AF NE++ L+ +K LE+ ++E T H+ EM + N KQ K ++
Sbjct: 6585 AFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKV 6644
Query: 1343 ------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
E+E+ + K L +D+ + ++ L+E+ NK + K LE+ E+ S
Sbjct: 6645 MIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-S 6703
Query: 1505 KLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 1684
K+++ R L + A + E L + RK LD K + +++
Sbjct: 6704 KIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVLDKIKVANESTLAD 6754
Score = 97.8 bits (242), Expect = 2e-17
Identities = 125/544 (22%), Positives = 241/544 (44%), Gaps = 32/544 (5%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQAL---EYKVADLEAAKTTLN 181
E KVA+ E+T+A + E N ++ ++ I +E K+ + E K+ L+A
Sbjct: 4779 EMKVAN-ESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQ 4837
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
E E++K N + A+ K + DL++ D++ + L
Sbjct: 4838 SETEKEKS-NIERERAAIIKDVEDLQSKIISLDRDAESLKL-------------DREAFE 4883
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
N + + + EL++E D+ + K + + ++ V E+ + ++ + R++
Sbjct: 4884 NEKEELKQMKTELEREADE---IEKIKLETQHDRQRVEEMTAQIQKE---------RDKI 4931
Query: 542 DEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNL 715
+ ++E + ++ I+ E K K A+ + + E EK LEKT L R NL
Sbjct: 4932 NNLIEETNRKDMVLNEIKTEIKEKIK----AIESDRDMLEKEKHDLEKTRSKLLRAKENL 4987
Query: 716 DTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLNDAL 874
+ I E++KE+ D + E + + E+ ++ LD L+ I +L L
Sbjct: 4988 EKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQEL 5047
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEK 1048
+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+ KEK
Sbjct: 5048 EKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEK 5107
Query: 1049 DD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 1216
D ++S+ DL +K ++QVLE + S +E L E + E NER LE
Sbjct: 5108 HDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLE 5167
Query: 1217 AVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISILTD 1378
+ + L++ DL + + D+ A + TL K + E+ E IS T+
Sbjct: 5168 KMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTE 5224
Query: 1379 KAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCICGAR 1534
+ +++ + E+ +LQ +++K+ KEK ++E + +E K IC R
Sbjct: 5225 DVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDR 5284
Query: 1535 DGLS 1546
D S
Sbjct: 5285 DAES 5288
Score = 97.4 bits (241), Expect = 2e-17
Identities = 131/545 (24%), Positives = 239/545 (43%), Gaps = 42/545 (7%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLND- 184
+ N + + LN+ K+ K I +DR++LE K LE + L AK L
Sbjct: 4931 INNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAKENLEKQ 4990
Query: 185 ------ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 346
E++++++D + +K I D+K Q Q+ D
Sbjct: 4991 RKIKLAEIQKEREDLEKMNEK-FTIEIHDIKHQEEQMKQKQDE----------------- 5032
Query: 347 XXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSR 508
+ L+ I L +EL+KEK+ D++ L DL +E K+ VN+I+ ++++ +
Sbjct: 5033 ---LDQLKTEIQNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNVNDIMETMKNERK 5087
Query: 509 SL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEK 685
L K+ EE+ + +E+ + + +E+L+ K K L + E K LE+
Sbjct: 5088 QLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELER 5147
Query: 686 TVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN 865
+E R + I E EK+ + AL E E E + + + +++ S
Sbjct: 5148 EAVEIRKIK----EEIQNERQNLEKMTE-ALKEEREDLAEETKKNNQVLDEMKVANESTL 5202
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKE 1045
+ R+ + ++ + K+ D+E K +N E E+ R+L+A E+ KE
Sbjct: 5203 ADILREKSNLEEMRENISKQTEDVENKK----ENLRLREDEL-RQLQAEIHKQQREIEKE 5257
Query: 1046 KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVK 1225
K + ES ER + V D++ L+ + + D EAF NE++ L+ +K
Sbjct: 5258 KINIES----------ERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMK 5307
Query: 1226 QGLEKRVLDLE----ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELE 1354
LE+ ++E T HD +++ +D+ N E+ L ++ ++E
Sbjct: 5308 TELEREADEIEKIKLETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIE 5367
Query: 1355 EAI-SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELT 1501
E I SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T
Sbjct: 5368 EKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENIT 5427
Query: 1502 SKLEK 1516
++ +
Sbjct: 5428 REMHE 5432
Score = 94.0 bits (232), Expect = 2e-16
Identities = 133/541 (24%), Positives = 243/541 (44%), Gaps = 54/541 (9%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 5812 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 5871
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5872 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5910
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5911 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5968
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 718
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 5969 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 6028
Query: 719 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 883
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 6029 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 6077
Query: 884 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1057
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 6078 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINI 6134
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
ES ER + V D++ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 6135 ES----------ERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 6184
Query: 1238 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 1363
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 6185 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 6244
Query: 1364 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 1513
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 6245 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 6304
Query: 1514 K 1516
+
Sbjct: 6305 E 6305
Score = 91.3 bits (225), Expect = 2e-15
Identities = 138/568 (24%), Positives = 250/568 (44%), Gaps = 63/568 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 166
+ LE+ + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3639 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3698
Query: 167 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 313
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3699 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3752
Query: 314 XXXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 475
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3753 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3796
Query: 476 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3797 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3851
Query: 653 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 808
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3852 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3905
Query: 809 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 979
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3906 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQ 3965
Query: 980 -EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 1156
+AEI ++ E+ KEK + ES ER + V D++ +L+
Sbjct: 3966 LQAEIHKQQR--------EIEKEKSNIES----------ERAAIIKIVEDLQHKIISLDR 4007
Query: 1157 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIE-------MKTGKDDD 1303
+ + D EAF NER+ L+ +K LE+ ++E T HD + T + D
Sbjct: 4008 DAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDK 4067
Query: 1304 YNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLNKE 1456
N ++T L ++ ++EE I SI +DK +K ++ SE+ +++EDL K+
Sbjct: 4068 INNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQ 4127
Query: 1457 --------SKEKQDLEKRVLELTSKLEK 1516
KE++DLEK +T ++ +
Sbjct: 4128 KENTLAEIQKEREDLEKMNENITIEMHE 4155
Score = 91.3 bits (225), Expect = 2e-15
Identities = 102/535 (19%), Positives = 239/535 (44%), Gaps = 32/535 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 5061 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5120
Query: 188 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXXI 355
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 5121 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5180
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 529
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 5181 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5240
Query: 530 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 667
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 5241 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 5299
Query: 668 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
K+ L+ KT LER A ++ + E + +++V++ A + E E D+
Sbjct: 5300 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 5357
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLT 1021
+ N ++ + + ++K LEK DLE + L +E E + E L
Sbjct: 5358 --VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA----- 5410
Query: 1022 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
E+ KE++D E+I ++ +K + + + K +++ + + N Q+ + E
Sbjct: 5411 ---EIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5467
Query: 1190 FLNERDGLEAVKQGLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEA 1360
+ +R L+ + L+K+ + D+ T+ + + KD + E +KQ ++K ++++
Sbjct: 5468 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 5527
Query: 1361 ISILTDKAKKLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
L + KK+ ++ E +L++ +L +E+ E +++ +LEK
Sbjct: 5528 RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 5582
Score = 89.4 bits (220), Expect = 6e-15
Identities = 114/525 (21%), Positives = 236/525 (44%), Gaps = 44/525 (8%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE K LE YKV DLE K E++++
Sbjct: 5356 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKE 5415
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5416 REDLEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5454
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5455 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5512
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT------VLER 700
+ + +E+ N+ + +E+ +K K K E E K LE+ + E
Sbjct: 5513 QKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEE 5572
Query: 701 RASNLDTMDAIHEEELRKE----------KVDKSALTEN---GEGCEAEKQGPEKTVLDL 841
+ ++ + EE +R++ K +K L E E A+ Q + + ++
Sbjct: 5573 TQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEM 5632
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNL 1018
I L + + + ++ + L+K ++++ + + + + E+E + E N+
Sbjct: 5633 RENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNM 5692
Query: 1019 THNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
EL K+ +D E I+ + + + +R++L V +++ L + ++ D E
Sbjct: 5693 M--TELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 5750
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS 1366
AF NE++ ++ +K L+ + ++E I+++T D E ++K ++ I
Sbjct: 5751 AFENEKEAMKQMKTDLQIQADEIE----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE 5806
Query: 1367 ILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLEL 1498
T++ +L + N + E + +Q D + KE+ +LEK EL
Sbjct: 5807 -ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSEL 5850
Score = 87.8 bits (216), Expect = 2e-14
Identities = 122/538 (22%), Positives = 233/538 (43%), Gaps = 24/538 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E++ E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 182 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 340
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 520
I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 521 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 682
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 683 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 832
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1009
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1010 SNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
++++ +++L KE+ ++E I N +K E LE ++ NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 1190 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 1369
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 1543
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 85.9 bits (211), Expect = 7e-14
Identities = 116/534 (21%), Positives = 238/534 (44%), Gaps = 34/534 (6%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLND 184
K+ + + +A L+ EL KD+ + I +R+ +E + L ++ +E + D
Sbjct: 9716 KMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQD 9775
Query: 185 ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSN 364
+ ++ +I +K + +I + + Q +QE N L I N
Sbjct: 9776 KQNHLEEKELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELN 9832
Query: 365 LEVN------ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK 502
+ N + + EL+ EK D K + L E K + ++ L+SK
Sbjct: 9833 KQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSK 9892
Query: 503 -SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
++ KE + ++R + + + + + + K+ L E E + E++ L
Sbjct: 9893 REQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKL 9952
Query: 680 E--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E K +++ A NL+ + + + K ++ ++ L E CE ++ E+ D+E I
Sbjct: 9953 EEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQI 10012
Query: 854 PSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EAS 1012
+ +A L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +
Sbjct: 10013 QNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKA 10072
Query: 1013 N--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL---QQKMD 1177
N L D+L KEK+D N LD ++ E Q + +++ NE+ QQ+++
Sbjct: 10073 NEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLE 10132
Query: 1178 DNEAFLNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 1354
++ +NE G LE ++ EK+ +E + +M E++ L + SELE
Sbjct: 10133 ESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELE 10181
Query: 1355 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ + + + KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 10182 KDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10235
Score = 85.5 bits (210), Expect = 9e-14
Identities = 103/492 (20%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = +2
Query: 71 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 238
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 239 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDD 418
+R+++++ + +++ D+ ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 419 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 598
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 599 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 778
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 779 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 958
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 959 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETT 1138
+ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 1309
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 1310 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 1453
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1454 --ESKEKQDLEK 1483
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 82.4 bits (202), Expect = 7e-13
Identities = 111/556 (19%), Positives = 242/556 (43%), Gaps = 54/556 (9%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL----------- 157
EN + E + +++ N ++ K + +R ++ KQ L+ + DL
Sbjct: 9995 ENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENV 10054
Query: 158 EAAKTTLNDELERKKDDNNAIIKKA--LDKRISDL-----KADAPQRDQEDDMNALIXXX 316
E +K +L++E + + N I+++ L+K D+ K D Q + +++ A+
Sbjct: 10055 EMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIK 10114
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEE------LQKEKDDKTALIKDL-VAAEPGKRTVN 475
LE ++ ++EE ++ + + + I+++ V A+ ++ ++
Sbjct: 10115 YELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELD 10174
Query: 476 EIVSHLESKSRSLKEHFLREEEDE-VLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I S LE + + + D ++E+ ++L MK+ + ++ +D +S L + +
Sbjct: 10175 QIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIK 10234
Query: 653 GCEAEKQGLEKT--VLERRASNLDTMD---AIHEEELRKEK---VDKSALTENGEGCEAE 808
EK +EK ++ER + ++ + +EEL E+ VD+ L CE E
Sbjct: 10235 EANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQ---CETE 10291
Query: 809 KQGPEKTVLDLEPTIPSLNDAL-------QRD-------LDRVMAEKQALEKRCSDLEAK 946
Q + + ++E + + + L QRD ++ +K+ LEK + + +
Sbjct: 10292 LQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQ 10351
Query: 947 NASLT---DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLES- 1114
L D E EI K ++ + + KE + + ++ ER+ LE
Sbjct: 10352 KQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEV 10411
Query: 1115 --KVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKT 1288
K+ +M+T ++E+ QK+++ L+ +++ + K EA ++M
Sbjct: 10412 NGKIIEMKTKAELEHHEINQKIEE----------LQTLQEQIMKEKEKAEAMTIKLKM-- 10459
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEK 1468
E++ L + SEL + + + KKL DI + E +L++ ++ +K
Sbjct: 10460 ---------EREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10510
Query: 1469 QDLEKRVLELTSKLEK 1516
Q++EK EL +K+++
Sbjct: 10511 QEMEKERSELDNKIQQ 10526
Score = 82.0 bits (201), Expect = 1e-12
Identities = 125/622 (20%), Positives = 261/622 (41%), Gaps = 52/622 (8%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + + + +I +L+++L K K+ I ++N LE K L+ + ++ K
Sbjct: 4238 QEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQ 4297
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXXXXXI 355
+E + + A+IK+ D + L A+ +R++E D+M I
Sbjct: 4298 NERQSLEKMTKALIKERED--LVHL-AEYTKREKEMLDEMQVA---NKSSMADLQREKRI 4351
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 535
+ + NI E+++ EK+ +L + + + ++ S + +RE
Sbjct: 4352 LEEMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIRE 4411
Query: 536 EEDEV--LERSASNLAI-MKAIREEELRKEKDGK-------------SALVENGEGCEAE 667
+++ + L++ + ++ I MK I E+ E D ++ + E + +
Sbjct: 4412 KQNMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLD 4471
Query: 668 KQ--GLEKTVLERRASNLDTMDAIHEEELRKEKV----DKSALTENGEGCEAEKQGPEKT 829
++ G EK VL++ ++L I +E+ K K+ D+ + E + ++
Sbjct: 4472 REAFGNEKEVLKQMKTDLQ----IQADEIEKIKLETQHDRQRVEEKTAQIQKDRDEINNL 4527
Query: 830 VLDLEPTIPSLNDALQRDLDR----VMAEKQALEKRCSDLEAKNASLTDNQEGHEA--EI 991
+++ LN+ + RD++ + ++K LEK +LE + L +E E EI
Sbjct: 4528 IVETNRKDMVLNE-MDRDIEEKIKSIQSDKDMLEKERHNLEKTRSELARAKENLETQREI 4586
Query: 992 ERK----------LEASNLTHNDELHKEKDD-----KESIMNDLDHVKAERQVLESKVSD 1126
ERK E + H +E K+K D K I N ++ E++++ S
Sbjct: 4587 ERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQ 4646
Query: 1127 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY 1306
++ S L+ + D E NER L+ K+ E++ ++E HD + D+
Sbjct: 4647 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDE- 4705
Query: 1307 NEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS-EVTELQEDLNKESKEKQDLEK 1483
+ + L+K++ E E K LK + I L E E+++ + E+Q EK
Sbjct: 4706 -DLKMMKLQKQVIEEE----------KSKLKQMKIELEREADEIRKVKEETQNERQIFEK 4754
Query: 1484 RVLELTSKLEKCICGAR------DGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPL 1645
L + E A+ D + E+ ++D + + +++ + S++T
Sbjct: 4755 MTEALKKEREDLSEDAKRKNQVLDEMKVANESTLADILRERS--NLQEMRENISKQTE-- 4810
Query: 1646 DITKTCDAVDISEDSTTNIQVD 1711
D+ + + + E+ +Q +
Sbjct: 4811 DVENKKEKIRLREEKLKQLQAE 4832
Score = 82.0 bits (201), Expect = 1e-12
Identities = 117/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N ++ E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 9400 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 9459
Query: 188 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 343
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 9460 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 9518
Query: 344 XXXIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 514
L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 9519 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 9573
Query: 515 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 9574 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9633
Query: 680 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9634 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9692
Query: 854 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1030
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9693 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 9747
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 1210
E H+ + + + + + ++ + Q+++ K + +E ++ + ++ N F E++
Sbjct: 9748 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 9807
Query: 1211 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 1390
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 9808 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 9853
Query: 1391 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 1516
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 9854 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 9895
Score = 81.3 bits (199), Expect = 2e-12
Identities = 121/518 (23%), Positives = 225/518 (43%), Gaps = 20/518 (3%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + E +L+ +DDK + NDR+ E LE K
Sbjct: 9207 QDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELK-----------R 9255
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+EL R+ +D + +K L +R D + +RD E+ AL
Sbjct: 9256 EELVRETED---LERKILQQREQD---EMAKRDIENQTEAL------------------E 9291
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
++V+IL E KE ++ V +E K + + L+S+ L+ EE+
Sbjct: 9292 VMKVDILKKRNEFAKEMEN--------VHSERQKLLL--LQGALQSQESELENRVFMEEQ 9341
Query: 542 DEVLERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
+ + A K + E E + E++ L+E + E E+ + K +E+ +L
Sbjct: 9342 KHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR-EKEQLEISKNQIEQEKKDL 9400
Query: 716 DTMDAIHE---EELRKEKV----DKSALTENGEGCEAEKQGPEKTVLDLE---PTIPSLN 865
M + E E LR EK +K+AL + + + K DLE I
Sbjct: 9401 QNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEK 9460
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
++ + R+ ++ ++K S+L+ ++ +E ++E +++ +E+
Sbjct: 9461 KRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIE 9520
Query: 1040 KEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 1219
KE + DL++ KAE Q E K D+ ++ ++Q+K + + L++ +
Sbjct: 9521 KESQRLQDATIDLENAKAEIQRQEDKFEDI------IDIKIQEKEREIKIQLDKE--TKR 9572
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKK 1390
+ + +E +V DLE + D++ + + +D E EKQ LK+ ELE+ + LT + ++
Sbjct: 9573 LSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQE 9632
Query: 1391 LLKDINIWLSEVTELQEDLNKES---KEKQDLEKRVLE 1495
++ N ++ +L EDL KE+ KEK LEK +E
Sbjct: 9633 TEEERNNLMALKNQL-EDLRKENEIVKEKLTLEKSNIE 9669
Score = 80.9 bits (198), Expect = 2e-12
Identities = 111/536 (20%), Positives = 231/536 (43%), Gaps = 46/536 (8%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 12093 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 12152
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 12153 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 12212
Query: 362 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 12213 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 12272
Query: 509 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 664
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 12273 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 12327
Query: 665 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 811
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 12328 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 12387
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 12388 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 12447
Query: 992 --ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 12448 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 12507
Query: 1154 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 1318
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 12508 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 12563
Query: 1319 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 1480
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 12564 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12616
Score = 80.1 bits (196), Expect = 4e-12
Identities = 94/521 (18%), Positives = 225/521 (43%), Gaps = 46/521 (8%)
Frame = +2
Query: 92 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 244
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 11761 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 11820
Query: 245 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEEL 400
I ++K ++++E+ M A + I S LE + E
Sbjct: 11821 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 11874
Query: 401 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 580
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 11875 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 11933
Query: 581 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 706
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 11934 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 11993
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 11994 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 12049
Query: 887 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1033
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 12050 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 12109
Query: 1034 LHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGL 1213
+ KEK+ +E V+ ER+ +E S +E S +++E ++ DD + E++ L
Sbjct: 12110 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 12169
Query: 1214 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 1393
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 12170 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 12228
Query: 1394 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 12229 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 12269
Score = 79.3 bits (194), Expect = 6e-12
Identities = 122/575 (21%), Positives = 250/575 (43%), Gaps = 74/575 (12%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K+ E T +++ EK+ ++ V R +E K+ L+ + LE ++ ++ E
Sbjct: 11538 ETKIKIIEMKTKTEPEKIKKEKEKEEEEVM-RAKVEMKKEELDQIKSQLERVRSEIDHEQ 11596
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 11597 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQ 11656
Query: 362 NLEV-------NILILHEEL----QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V +I + EEL QK D++ ++++ + + E+ ++ +
Sbjct: 11657 KLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKE 11716
Query: 509 SLKE---HFLREEED-------------EVLERSASNLA-----------IMKAIREE-- 601
+LKE H +E+E+ E LE+ ++++ ++K REE
Sbjct: 11717 TLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEIN 11776
Query: 602 ----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE--KV 763
+L++ D A V + + KQ K + E R S +T I E + + E K+
Sbjct: 11777 HKWTQLQQRIDEFDAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKI 11833
Query: 764 DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEA 943
K E E A+ + ++ + ++ + + + + ++ +K+ +E+ DLE
Sbjct: 11834 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11893
Query: 944 KNASLTDNQEGHE---AEIERKLEASNLTHND-ELHKE---------KDDKESIMNDLDH 1084
+ + ++ E +E+E K+ + + D E KE ++ K I +
Sbjct: 11894 MKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEE 11953
Query: 1085 VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEAT 1264
+ ERQ + + + S L NE ++ + NE ER+ L+ ++ LEK ++++
Sbjct: 11954 LDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI 12013
Query: 1265 IHDIEMKTGKDD-----DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVT 1429
E + K+D + +KQ L+ + LE+ + K K+L + I+ + ++V+
Sbjct: 12014 TE--ETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 12071
Query: 1430 -ELQEDLNKESKEKQD------LEKRVLELTSKLE 1513
+ +EDL KE + K+D + +LE+ +K E
Sbjct: 12072 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAE 12106
Score = 78.6 bits (192), Expect = 1e-11
Identities = 115/572 (20%), Positives = 245/572 (42%), Gaps = 91/572 (15%)
Frame = +2
Query: 56 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 193
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 6458 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 6517
Query: 194 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 331
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6518 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 6577
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 499
N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 6578 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6634
Query: 500 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 676
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6635 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6694
Query: 677 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 808
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6695 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 6754
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 988
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 6755 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 6814
Query: 989 IERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
+ E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 6815 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 6872
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 1294
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6873 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 6932
Query: 1295 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 1420
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 6933 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 6988
Query: 1421 EVTELQEDLNKESKE------KQDLEKRVLEL 1498
E+ + + L K SKE K + EK+ ++L
Sbjct: 6989 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 7020
Score = 77.8 bits (190), Expect = 2e-11
Identities = 108/524 (20%), Positives = 230/524 (43%), Gaps = 31/524 (5%)
Frame = +2
Query: 38 TIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL---NDELERKKDD 208
T+ + L EK++ K I + K+ LE D++ L D LE++K+D
Sbjct: 10603 TLKEMEAHLEKEKEEMKSITEETR---RQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKED 10659
Query: 209 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILIL 388
N + L +RI + A ++ +ED I + + +
Sbjct: 10660 INHEWTQ-LQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDI 10718
Query: 389 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE--VLERS 562
+E +KE++++ +K E + ++ I S L+ + RS +H ++ D+ ++E+
Sbjct: 10719 KKEKEKEEEEEEMRVK----VEMDGKELDRIKSELK-RERSEIDHEQKKLNDDKKIIEQE 10773
Query: 563 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE 742
NL MK+ ++ ++ ++ +S L + EK +E + + ++ + HE
Sbjct: 10774 KQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEI 10833
Query: 743 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 922
+ +KE++D E+Q + D + + LQ + +R+ + ++K
Sbjct: 10834 QFQKEELD------------IERQ----KIADEQDLLIQNKSELQNENERIRNLNEIIKK 10877
Query: 923 RCSDLEAKNASLTDNQEGHEAEIE--RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAE 1096
L+ A L +E ++ E R+L+ + +++K+ D +MN D ++ E
Sbjct: 10878 ERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKD---LMNQRDLLEQE 10934
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IH 1270
R+ + K +LQQ++D+ +A ++++ + K+ G+++ LE T +
Sbjct: 10935 REEINHKWK-----------QLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 10983
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL------------------ 1396
IEMKT + + + EK+ + E EE I ++ + +K L
Sbjct: 10984 VIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQ 11043
Query: 1397 KDINIWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEK 1516
K +N ++ + + +EDL K K++Q +E+ EL +K+++
Sbjct: 11044 KKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQ 11087
Score = 76.6 bits (187), Expect = 4e-11
Identities = 112/520 (21%), Positives = 215/520 (41%), Gaps = 22/520 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA------- 166
+EN F+ IA L + K DK+ I N+ L+ +Q E + + +
Sbjct: 14754 IENITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYD 14813
Query: 167 -----KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 331
KT L D E+KK D ++ +K ++D AD+ + D E + L
Sbjct: 14814 EKVTYKTELEDSKEKKKPDRDSSLK------LTD--ADSAKTDGEREAQTL--------- 14856
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
V L EEL E ++K +I +L A+ + + L+ + RS
Sbjct: 14857 --ETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAK-------KDLQKLKEECRS 14907
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KT 688
+E + E LER ++L E+++ E + +++ + E Q +E K
Sbjct: 14908 AEEE--KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKM 14957
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPS--- 859
++ R+ + ++ ++ +T+ E + K+ + TV LE T+ S
Sbjct: 14958 QIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQ 15017
Query: 860 -LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDEL 1036
+ D+L ++++ V K ++ LE + + E E +E +E + + ++L
Sbjct: 15018 EMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKL 15076
Query: 1037 HKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER 1204
+ DKE + N LD ++ + K++ +ETT + +
Sbjct: 15077 LQLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETTIVLMKKD--------------- 15121
Query: 1205 DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDK 1381
K+ +E +L L+ T + E++ G DD NE EK K +ELE+ +
Sbjct: 15122 ------KENIENELLQLKQTEQEREIQRGTDDTSNEREKYDEKVTYKTELED-----NKE 15170
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
KK +D ++ L++ + D +E++ + + VL+LT
Sbjct: 15171 KKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 15210
Score = 76.3 bits (186), Expect = 5e-11
Identities = 125/547 (22%), Positives = 241/547 (44%), Gaps = 47/547 (8%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT---TLNDE 187
K+AD + + EL NE + I N I++ ++ L+ A LE K ++++E
Sbjct: 10846 KIADEQDLLIQNKSELQNENER---IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEE 10902
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R K+D L+K +D+ +D + + L +
Sbjct: 10903 TRRLKED--------LEKMSTDVNKQ--NKDLMNQRDLLEQEREEINHKWKQLQQRIDEF 10952
Query: 368 EVNILILHEE-LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES---KSRSLKEHFLRE 535
+ + E+ L KEK K +D + E K V E+ + E K KE+ E
Sbjct: 10953 DAQVSKQKEQDLPKEKGMK----EDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEE 11008
Query: 536 EEDE----VLERSASNLAIMKAIREEELRKEKDGKSA-LVENGEGCEAEKQGLEKTV--- 691
EE+E ++E L +K+ E +R E D + L + + E EK+ LEK
Sbjct: 11009 EEEEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEI 11067
Query: 692 ------LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDL 841
+E S LD + I + L K ++KS E E+Q + K LD+
Sbjct: 11068 MKQRQQMEEERSELD--NKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDI 11125
Query: 842 E-PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNL 1018
E I + L ++ ++ E + ++K +++ + +L E EI K E L
Sbjct: 11126 ERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETL------REMEIHLKKEKEEL 11179
Query: 1019 THN-DELHKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 1183
+E + K+D E + D++ H+K +R +LE + ++ + +LQQ++D+
Sbjct: 11180 RSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT----QLQQRIDEF 11235
Query: 1184 EAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDIEMKTGKDDDYN-----EA 1315
+A +++ + +E ++ LE+ R+++++ A + +I + ++D+ E
Sbjct: 11236 DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVEM 11295
Query: 1316 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 1495
E++ L + SEL+ S + + KKL D I E +L++ ++ ++Q +E+ E
Sbjct: 11296 EREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSE 11355
Query: 1496 LTSKLEK 1516
L +K+++
Sbjct: 11356 LDNKIKQ 11362
Score = 75.9 bits (185), Expect = 7e-11
Identities = 111/513 (21%), Positives = 213/513 (41%), Gaps = 67/513 (13%)
Frame = +2
Query: 179 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXI 355
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 535
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 536 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 682
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 683 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 805
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 806 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 928
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 929 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAE 1096
DL+ + A + +E E+E+ + N D E K E D K ++ + ++++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 1276
R+++E + +E L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 1277 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 1417
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 1418 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 75.5 bits (184), Expect = 9e-11
Identities = 110/522 (21%), Positives = 225/522 (43%), Gaps = 35/522 (6%)
Frame = +2
Query: 5 ALENKVADFE---ATIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEA 163
A + + DFE I N EL ++++ K + + R LE + + +V +
Sbjct: 7199 AFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITN 7258
Query: 164 AKTTLND---ELERKKDD-----------NNAIIKKA--LDKRISDLKADAPQRDQEDDM 295
+L+ EL + ++D N I+ + LD+R SD+ D Q++ +D M
Sbjct: 7259 ENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQKEVDDLM 7316
Query: 296 NALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVN 475
+ ++N+E L + + + K D +L + A E + +N
Sbjct: 7317 D--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLN 7362
Query: 476 EIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E +E + L ++ ++D++ ++R NL + K + E ++ + K +L
Sbjct: 7363 EEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAI 7422
Query: 653 GCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ 814
G + +EK E+ ++E A+ LD + E + +E++D++ +
Sbjct: 7423 GFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLF 7482
Query: 815 GPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 994
EKT DL+ T +N D + + ++ L K E E
Sbjct: 7483 QEEKT--DLQKTKEEIN----YDREEIYRQRTELNK-------------------EKETL 7517
Query: 995 RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKM 1174
+++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + + E +
Sbjct: 7518 KQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELA 7574
Query: 1175 DDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ---TLKKRIS 1345
D E NE+D L+ ++ ++K + +L+ E + + N+ +Q +K +
Sbjct: 7575 RDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTEEIKLKND 7628
Query: 1346 ELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 1465
L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7629 SLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7670
Score = 75.5 bits (184), Expect = 9e-11
Identities = 105/540 (19%), Positives = 219/540 (40%), Gaps = 57/540 (10%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 13412 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13461
Query: 221 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEV 373
+ AL+K + DL+ + +++NAL+ E
Sbjct: 13462 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 13502
Query: 374 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 532
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 13503 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 13561
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 13562 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13615
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 892
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13616 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13675
Query: 893 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1042
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13676 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13734
Query: 1043 EKDDKESIMNDL----------------------------DHVKAERQVLESKVSDMETT 1138
EKD E I DL D + + + L S +D+E
Sbjct: 13735 EKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQ 13794
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 13795 AKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDLT 13836
Query: 1319 KQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL ++
Sbjct: 13837 LQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQL 13896
Score = 74.3 bits (181), Expect = 2e-10
Identities = 104/548 (18%), Positives = 241/548 (43%), Gaps = 47/548 (8%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
++++ + I L EL EK+ I+ DR+ L+ K ++L+ +T +ND +
Sbjct: 3750 QDELDQLKTEIQNLQQELEKEKE---IIMKDRS-------ELDLKQSELDKQQTNMNDII 3799
Query: 191 ERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLE 370
E K++ + K + + + + D + N+L + +
Sbjct: 3800 ETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSL-------------------DED 3840
Query: 371 VNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKSRSLKEHFLREEED- 544
+ ++ L +++ +E+ +K +K + E G+ R + E + + + E RE+E
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 545 ----EVLERSASNLAIMKAIREE---ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 703
E ++ L +K E EL+KEK + EN + E +K L R
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISK-QTEDVKNKKENLRLR 3959
Query: 704 ASNLDTMDA-IHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLN---DA 871
L + A IH+++ EK +KS + E+E+ K V DL+ I SL+ ++
Sbjct: 3960 EDELGQLQAEIHKQQREIEK-EKSNI-------ESERAAIIKIVEDLQHKIISLDRDAES 4011
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDN--QEGHEAEIERKLEASNLTHNDELH-- 1039
L+ D + E++ L++ ++LE + + + H+ + ++ A D+++
Sbjct: 4012 LKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINNL 4071
Query: 1040 -KEKDDKESIMND--------LDHVKAERQVLESKVSDMETTYSTL---NNELQQKMDDN 1183
+E + K+ ++N+ + +++++ +LE + ++E T S L +L+++ ++
Sbjct: 4072 IEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQKENT 4131
Query: 1184 EAFLN-ERDGLEAVKQGL-----------------EKRVLDLEATIHDIEMKTGKDDDYN 1309
A + ER+ LE + + + + + L+ I +++ + K+ +
Sbjct: 4132 LAEIQKEREDLEKMNENITIEMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEII 4191
Query: 1310 EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
++ L R SEL++ + + D + + + + + E++E + KE+ ++++ +
Sbjct: 4192 MKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQEMEKERDNMDQSI 4251
Query: 1490 LELTSKLE 1513
L L+
Sbjct: 4252 KSLDEDLK 4259
Score = 74.3 bits (181), Expect = 2e-10
Identities = 122/611 (19%), Positives = 247/611 (40%), Gaps = 64/611 (10%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELER 196
+V + L E+ ++ K ++++ I ++ Q L + + L E+E
Sbjct: 8801 EVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIEN 8860
Query: 197 KKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVN 376
K D K L+K ++L + Q+++E L ++E++
Sbjct: 8861 TKRD-----KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEIS 8913
Query: 377 ILILHEEL-----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES-------- 499
++ E+ QK K++ + ++L+ + +N V HL
Sbjct: 8914 RELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQ 8973
Query: 500 --KSRSLKEHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDG 625
K ++ EH E + +++LE+ L +++I E L+K +D
Sbjct: 8974 YIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED- 9032
Query: 626 KSALVENGEGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGE 793
+ + E EKQ E + L+R+ +++ I E++ K K+D E
Sbjct: 9033 ---MEKEKENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSA 9088
Query: 794 GCEAEKQGPEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEA 943
E E + E DLE SLNDA LQ+ + + EK+ +E+ ++
Sbjct: 9089 AFEKEHKRLENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKT 9148
Query: 944 KNASLTDNQE-----------GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD-HV 1087
+ + +E GHE ++++K E + D+L ++ + + + DL +
Sbjct: 9149 ERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKL 9202
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 1267
+ +RQ +E ++MET +L+ ++ DD N+RD E LE + +L
Sbjct: 9203 QMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRET 9262
Query: 1268 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 1447
D+E K + + +E K+ ++ + LE + K + K++ SE +L
Sbjct: 9263 EDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQ 9322
Query: 1448 NKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGF 1624
++ +LE RV +E L++ + + E MS+ + + + L++
Sbjct: 9323 GALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEEL 9379
Query: 1625 SRKTSPLDITK 1657
R+ L+I+K
Sbjct: 9380 QREKEQLEISK 9390
Score = 73.6 bits (179), Expect = 3e-10
Identities = 109/526 (20%), Positives = 232/526 (44%), Gaps = 23/526 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N+ D E + + DE N + K+ + +DR+ LE + DLE KT + +
Sbjct: 3046 LQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKER-------FDLEKTKTEMGN- 3097
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
+KK L+ +I + + +E + I+ L
Sbjct: 3098 -----------LKKQLESQIRQHEIQLVEIQKERE--------------------ILEQL 3126
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKSRSLKEHFLREEED 544
++N+ E+L+KE+D D+ +E K ++ E + + ++ +++E D
Sbjct: 3127 KINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTR--------IKQEMD 3178
Query: 545 EVLERSASNLA-------IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 703
E LE++ NLA + K I E+E K + K+ L + E + E Q E+ LE
Sbjct: 3179 E-LEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQN-ERQNLEEA 3236
Query: 704 ASNL----DTMDAIHEEELRKEKVDKSALTE---NGEGCEAEKQGPEKTVLDLEPTIPSL 862
+ L + ++++ EE RK+ V ++ E + E+ KQ E+ +++L+ T+ +
Sbjct: 3237 GTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTVTDI 3296
Query: 863 NDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHK 1042
A + ++++ E++ + + ++++A+ L ++G E++++ N T L +
Sbjct: 3297 AGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGIS---EQQVDIVNKTEQLRLRE 3353
Query: 1043 EKDD--KESIMNDLDHVKAERQVL---ESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
+ + + I D ++A R+ + + ++ +T L E+ Q M+ +D
Sbjct: 3354 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMME-----YASKD 3408
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAK 1387
+ LEK ++ A H ++++ K+ E Q L E+++ + L + K
Sbjct: 3409 -----RANLEKEKSEMIAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMK 3463
Query: 1388 KLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
+L E +LQ+ +L +E+ + + L+++ LEK
Sbjct: 3464 ELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEK 3509
Score = 72.8 bits (177), Expect = 6e-10
Identities = 117/569 (20%), Positives = 233/569 (40%), Gaps = 66/569 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAK 169
Q+ + + + + T+ L DE +++ + N+ ++ K +LE ADL+
Sbjct: 13691 QSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRKA 13750
Query: 170 TTLNDELERKKDDNNAIIKKAL--------DKRISDLKADAPQRDQ--EDDMNALIXXXX 319
L++E+ + + I + A ++ + ++AD ++ + E D+ L
Sbjct: 13751 EKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKE 13810
Query: 320 XXXXXXXXXXXIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 487
+ +LE N L L +EL+KEK +I D+ + + V+
Sbjct: 13811 ILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------DAVA 13862
Query: 488 HLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 13863 SLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR 13921
Query: 662 AEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTENGE 793
+ + ++ + E R D + DA+ + +EL K D E+ E
Sbjct: 13922 NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVE 13981
Query: 794 GCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA------- 943
E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 13982 KEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKT 14041
Query: 944 -----KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH--- 1084
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 14042 LVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEV 14101
Query: 1085 ------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGLEKR 1243
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +E
Sbjct: 14102 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE-- 14159
Query: 1244 VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 1423
+EKQ++++ +EL K+L +++ + E
Sbjct: 14160 -----------------------SEKQSIERERAEL-----------KRLKEEVEVQ-HE 14184
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKL 1510
T LQ+D N KEK+ LE T ++
Sbjct: 14185 RTLLQQDKNMIQKEKEHLEGEKARTTEEI 14213
Score = 71.6 bits (174), Expect = 1e-09
Identities = 107/531 (20%), Positives = 221/531 (41%), Gaps = 28/531 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
++ ++ + E T + EL N + K+ I ++R+ +E K L+ + D E + + ++
Sbjct: 2779 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2838
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++++ +IK +K+ + D + +
Sbjct: 2839 ---RRNNEEMVIKLQNEKKDIETSTDR-----------------------------IRDE 2866
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEED 544
E N+ +L + L+ ++D L K+ + + ++ LES++R + ++E
Sbjct: 2867 EANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKER 2923
Query: 545 EVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
E+LE+ L+ K E+E KEK S E E ++E++G+ KT R
Sbjct: 2924 EILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIK 2977
Query: 716 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 895
MD EL++ +++ EN E +KQ ++ + D++
Sbjct: 2978 KEMD-----ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKI 3011
Query: 896 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDK 1057
K L+K D E + + ++ +E + ++ +E S DE + K
Sbjct: 3012 EQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQK 3071
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
+ + +D D ++ ER LE ++M L ++++Q ER+ LE +K L
Sbjct: 3072 QRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLS 3131
Query: 1238 KRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL---- 1372
K+ DLE E + +D ++E++ +K+ + ELE+ L
Sbjct: 3132 KQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQ 3191
Query: 1373 --TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3192 ENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 71.6 bits (174), Expect = 1e-09
Identities = 111/536 (20%), Positives = 234/536 (43%), Gaps = 60/536 (11%)
Frame = +2
Query: 86 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERK-KDDNNAIIKKALDKRISD 253
K + NDRN++E + LE ++L + + DE L++K K+ N K +K I +
Sbjct: 10192 KKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVE 10251
Query: 254 LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKE----KDDK 421
+ A +Q +D +++ E + E+++ K+++
Sbjct: 10252 -RLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNER 10310
Query: 422 TALIKDLVAAEPGKRTVNEIVSHLESKSRSL----------------KEHFLREEEDEV- 550
L + + K+ + I+ + L K+ L +E +E+
Sbjct: 10311 ETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEIN 10370
Query: 551 ------LERSASNLAIMKAIREEELRKEK---DGKSALVE-NGEGCEAE-KQGLEKTVLE 697
+R A ++ +EE+L +K + + L E NG+ E + K LE +
Sbjct: 10371 HKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEIN 10430
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT-IPSLNDAL 874
++ L T+ +E++ KEK A+T + E E K+ L E T + L
Sbjct: 10431 QKIEELQTL----QEQIMKEKEKAEAMTIKLK-MEREDLDQIKSELVREKTEVDHEQKKL 10485
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
D+ + EK+ LEK S++ + + E +E++ K++ ++L +D + K K+
Sbjct: 10486 NDDIKMIEQEKEDLEKMKSEIMTQKQEM----EKERSELDNKIQQTDLEKHD-IEKSKEI 10540
Query: 1055 KESIMNDLDHVKAERQVLES-------KVSDMETTY----STLNNELQQKMDDNEAFLNE 1201
E +M +++ + E Q+ + K++D + S L NE ++ + NE E
Sbjct: 10541 VEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKE 10600
Query: 1202 RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------DYNEAEKQTLKKR--ISELEE 1357
R+ L+ ++ LEK ++++ E + K+D D E + +K+R + + +E
Sbjct: 10601 RETLKEMEAHLEKEKEEMKSITE--ETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKE 10658
Query: 1358 AISILTDKAKKLLKDINIWLSEVTE----LQEDLNKESKEKQDLEKRVLELTSKLE 1513
I+ + ++ + + + +S+ E Q+++ +E K ++ + R++E+ +K E
Sbjct: 10659 DINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAE 10714
Score = 71.6 bits (174), Expect = 1e-09
Identities = 109/563 (19%), Positives = 243/563 (43%), Gaps = 50/563 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LER 196
D E+ L++E +D+ K + +N+L +K + +LE T + E +E+
Sbjct: 13923 DLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEK 13982
Query: 197 KKDD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXX 346
++++ N IIK ++L+ I K + A +R Q + + L
Sbjct: 13983 EREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTL 14042
Query: 347 XXIVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
+ + + L LQK+K++ L ++ + AE K V L+ + +
Sbjct: 14043 VQTEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQK 14099
Query: 509 SLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----E 661
+++ + + E +VLE+ S L + + E++++E++ L+E E C E
Sbjct: 14100 EVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE 14159
Query: 662 AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
+EKQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L
Sbjct: 14160 SEKQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNL 14216
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQ 970
+ I + L + A++Q E K+ D+ E TD
Sbjct: 14217 KEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDAS 14276
Query: 971 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL----ESKVSDMETT 1138
+ + + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 14277 QKFQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEM 14335
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
LNNE+++ E+D L+ K ++ ++ + E + + + +++
Sbjct: 14336 RDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE------ 14389
Query: 1319 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 1498
+ L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 14390 -EKLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQL 14448
Query: 1499 TS-KLEKCICGARDGLSTIKEAW 1564
+ E+ I D ST KE +
Sbjct: 14449 KQIEQEREIQRKADVTSTEKEMY 14471
Score = 70.9 bits (172), Expect = 2e-09
Identities = 120/625 (19%), Positives = 268/625 (42%), Gaps = 75/625 (12%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNE----KDDKKCIVNDR-NILEAAKQALEYKVADLEAAKT 172
L+ ++ +F+A ++ ++ L + K+D+K + + N++E +A + +++ K
Sbjct: 10945 LQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKA---EPEEIKKEKE 11001
Query: 173 TLNDELERKKDDNNAII---KKALDKRISDLKADAPQRDQE----DDMNALIXXXXXXXX 331
N+E E ++++ I+ +K L + S+L+ + D E +D +I
Sbjct: 11002 KENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKED-- 11059
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
+ ++ I+ +++++E+ + I+ + H KS+
Sbjct: 11060 --------LEKMKSEIMKQRQQMEEERSELDNKIQQ-----------TNLEKHDIEKSKE 11100
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV 691
+ E + E E++ ++ + K + E +K D ++ LV+N + E + ++K V
Sbjct: 11101 IVEKLMVEVEEQ-----RKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKK-V 11154
Query: 692 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
E +T+ + E L+KEK + ++ E + + + + + + + + + D
Sbjct: 11155 DEEIKKERETLREM-EIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDL 11213
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK---------LEASNLTH 1024
L+++ + + E L++R + +A+ + ++ E E ERK +E
Sbjct: 11214 LEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAE 11273
Query: 1025 NDELHKEKDDK-ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE 1201
E+ +EK+++ E M + V+ ER+ L S+++ S +++E ++ DD + E
Sbjct: 11274 LQEIMQEKEEEDEEEMRVI--VEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQE 11331
Query: 1202 RDGLEAVK-------QGLEKRVLDLEATI-------HDIE-------------------M 1282
++ LE +K Q +E+ +L+ I HDIE +
Sbjct: 11332 KEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDI 11391
Query: 1283 KTGKDD---------------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 1417
+ K++ N+A+ Q +RI E++E I K K+ LK++ L
Sbjct: 11392 RLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHL 11447
Query: 1418 SEVTELQEDLNKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 1591
+ E + +E+ ++K+DLEK ++ +K + + RD L +E +
Sbjct: 11448 RKEKEEMRSVIEETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHK 11500
Query: 1592 WVPFEDLVQGFSRKTSPL---DITK 1657
W + + F + S D+TK
Sbjct: 11501 WTQLQQRIDEFDAQVSKQKEEDLTK 11525
Score = 69.3 bits (168), Expect = 7e-09
Identities = 116/533 (21%), Positives = 226/533 (42%), Gaps = 17/533 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ +E KQ +E + +++ ++ +L+++
Sbjct: 5475 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 5534
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++ K + K+ ++ + L+ + ++E D + I N
Sbjct: 5535 QKKMK-----LQKQMFEEEKNKLEQMKIELEREADEISKIKEE-------------TQNK 5576
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
+ + EEL +EK+ L +D + K+ ++E+ ES L + E
Sbjct: 5577 RQRLEKMTEELIREKESLAHLAED---TKTEKKILDEMKVANESSMADL------QREKS 5627
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSAL--VENGEGCEAEKQGLEKTVLERRASNLDT 721
+LE N++ +K + E K K + L ++ + K +EKT +E + +
Sbjct: 5628 ILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIR 5687
Query: 722 MDAIHEEELRKEKVD-----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
EL+K+ D K LTE E + D+E L D L+RD
Sbjct: 5688 EKQNMMTELKKKSEDVEIQMKEILTEK----ELLHNDRKLLTRDVENLQQKLID-LERDS 5742
Query: 887 DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDE-----LHKEK 1048
R+ +++A E ++ EA TD Q + EIE+ KLE + E + KE+
Sbjct: 5743 KRLKLDREAFE---NEKEAMKQMKTDLQIQAD-EIEKIKLETQHDRQRVEEMAAQIQKER 5798
Query: 1049 DDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 1228
D I N ++ + VL K D+E ++ ++ + R L VK+
Sbjct: 5799 D---KINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKE 5855
Query: 1229 GLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDIN 1408
LEK+ E T+ +I+ + + NE + + + I EE ++ D+ +L
Sbjct: 5856 DLEKQ---KENTLAEIQKEREDVEKMNENITREMHE-IKHQEEQMNQKQDELDQL----- 5906
Query: 1409 IWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEKCICGARDGLSTIK 1555
+E+ LQ++L KE K++ + R S+L+K D + T+K
Sbjct: 5907 --KTEIQNLQQELEKEKEIIMKDRSQFDLR----QSELDKQQTNMNDIMETMK 5953
Score = 68.9 bits (167), Expect = 9e-09
Identities = 117/544 (21%), Positives = 231/544 (42%), Gaps = 39/544 (7%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDD--------KKCIVNDRNILEAAKQALEYKVADL 157
Q AD E + EL KD+ +K V+ + + +++ E +L
Sbjct: 1711 QTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIEL 1770
Query: 158 EAAKTTLN---DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 328
E A+ LN ++E +K A +K L K +L+A ++ ED+ AL
Sbjct: 1771 EKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ--RKMMEDEKRALENMKYELQ 1828
Query: 329 XXXXXXXXIVSNLEVNILILH----------EELQKEKDDKTAL-------IKDLVAAEP 457
N+ + EEL+K++ D L IKDL
Sbjct: 1829 RESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDL----E 1884
Query: 458 GKRTVNEI-VSHLESKSRSLKE-HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 631
R +NE+ ++ +++KS L++ L ++ + +E S + I RE +L++ + +
Sbjct: 1885 NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKI----REYDLQQMQTDLN 1940
Query: 632 ALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG-EGCEAE 808
+ E Q ++ V ++ + D I E+ K+ D T+N + + E
Sbjct: 1941 RQ-------QKEMQDIQNAVFMEKSELKKSQDEIAEQ--LKQVGDMMQFTQNEKDNLDRE 1991
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRV-MAEKQALEKRCSDLEAKNASLTDNQEGHEA 985
+ + L +E + L L R+L+ + + +K+ L ++ + + + + D Q+ +
Sbjct: 1992 RAAIIEQKLQMERDMTHL---LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQM 2048
Query: 986 EI--ERKLEASNLTHNDELHKEKDDKESIMNDL--DHVKAERQVLESKVSDMETTYSTLN 1153
+I ER+ E L + +EKD ES++ L D K L K +E L
Sbjct: 2049 KINLEREKEEMQL-QRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK-QKLEDAAVELQ 2106
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 1333
E + M+ E +R+ ++ ++ G+EK+ E T D++ K+ E ++Q ++
Sbjct: 2107 KERDEIMNIAEETKRKREDVDKIRVGIEKQ----EITFKDLKADLQKEAAIVENQRQAVQ 2162
Query: 1334 K---RISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
K + ++E I +L+++I + E+Q +++KE +E + + + TS
Sbjct: 2163 KDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETS 2222
Query: 1505 KLEK 1516
KL +
Sbjct: 2223 KLRE 2226
Score = 68.9 bits (167), Expect = 9e-09
Identities = 104/526 (19%), Positives = 213/526 (40%), Gaps = 32/526 (6%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKC----IVNDRNILEAAKQALEYKVADL------ 157
L+ V D L ++LL E++ K I ++++L KQ + + D+
Sbjct: 3289 LKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQ 3348
Query: 158 ----EAAKTTLNDELERKKDDNNAIIKKALDK--RISDLKADAPQRDQEDDMNALIXXXX 319
E L + R++D+ A K +++ R+ K + + +E +
Sbjct: 3349 LRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKD 3408
Query: 320 XXXXXXXXXXXIVSNLEVNILILHEELQKEK---DDKTALIKDLVAAEPGKRTVNEIVSH 490
I +++I EL KE+ +++T ++ KRT E+
Sbjct: 3409 RANLEKEKSEMIAQKHQMDI-----ELNKERGLIEERTQMLNTYEKEMDQKRTALEV--- 3460
Query: 491 LESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E K + ++EE++++ L+R A ++ +K E+ R E+ + EN
Sbjct: 3461 -EMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLK----EKTRNERQSLEKMAEN-- 3513
Query: 653 GCEAEKQGLEKTVLERRASNLDTMDAIHEE---ELRKEKVDKSALTEN----GEGCEAEK 811
E EK L + + + D M +HE +++KEK + + E+ E ++EK
Sbjct: 3514 -LEKEKDDLAHLAEDTKRKD-DEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEK 3571
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
K ++ E + + + R + +K +E + + KN L
Sbjct: 3572 ----KKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMT--------- 3618
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQK 1171
EL K+ +D E M + V E+++LES ++ L +L
Sbjct: 3619 -------------ELTKQSEDVEIQMKE---VLTEKELLESDRKLLKKDVENLQQKLLII 3662
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 1351
D+E+ +R+ LE K+ L++ DL+ +IE K + + + + +I +
Sbjct: 3663 ESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE-KIKLETQHERQRVEEMTAQIQKD 3721
Query: 1352 EEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
E + + D + + DI ++ + Q++L++ E Q+L++ +
Sbjct: 3722 REYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQEL 3767
Score = 68.6 bits (166), Expect = 1e-08
Identities = 121/564 (21%), Positives = 227/564 (40%), Gaps = 64/564 (11%)
Frame = +2
Query: 17 KVADFEATIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 193
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 13077 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 13134
Query: 194 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 13135 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 13176
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 13177 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 13236
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 721
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 13237 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 13292
Query: 722 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 874
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 13293 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 13350
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKLEA 1009
+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 13351 EESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRERE 13410
Query: 1010 SNLTHNDELHKEKDD----KESIMNDLDHV----------KAERQVLESKVSDMETTYST 1147
D+L KEK+D KE I + +H+ K E + K+ M+T
Sbjct: 13411 EIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQV 13470
Query: 1148 LNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATIHD 1273
N L++ M D + ER+ + A+ K+ ++ +L +++ D
Sbjct: 13471 KTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 13527
Query: 1274 IE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 1444
IE +K + N+ +K LK R ELE I KK K+ ++ E+Q +
Sbjct: 13528 IESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQRE 13577
Query: 1445 LNKESKEKQDLEKRVLELTSKLEK 1516
K +LE++ EL +K+EK
Sbjct: 13578 RKALEKMNAELERKSTELKNKIEK 13601
Score = 65.9 bits (159), Expect = 7e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = +2
Query: 461 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 637
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 638 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 817
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 818 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 998 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 1126
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 1127 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 1303
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 1304 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 1462
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 1463 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 1627
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 1628 RKTSPLDITKT-----CDAVDISEDST 1693
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 1e-07
Identities = 118/608 (19%), Positives = 236/608 (38%), Gaps = 108/608 (17%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKT 172
++ D E + LN+ LN+ K ++ ++ +E K ++ + DL+ +T
Sbjct: 1879 EIKDLE-NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1937
Query: 173 TLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 346
LN + + +D NA+ K L K ++ A Q Q DM
Sbjct: 1938 DLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK--------- 1985
Query: 347 XXIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
NL+ I+ ++LQ E+D L ++L + + K+ V LE SL
Sbjct: 1986 ----DNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRD 2041
Query: 524 FLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKT 688
E+ ++ LER + + + EE K + L E+ E AEKQ LE
Sbjct: 2042 MQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDA 2101
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDK----------------------SALTENGEGC- 799
+E + + M+ E + ++E VDK +A+ EN
Sbjct: 2102 AVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAV 2161
Query: 800 --------------EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 937
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +L
Sbjct: 2162 QKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDEL 2217
Query: 938 EAKNASLTDNQEGHEAEIER----KLEASNLTHNDELHKEKDDKESIMNDLD-------- 1081
E + + L ++++ + E+ + E + N EL E KE + +L+
Sbjct: 2218 EQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRE 2277
Query: 1082 -------------------------HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
++A++ K ++T L+++ + E
Sbjct: 2278 NEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEME 2337
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKK 1336
+ E + +E K+ + ++ E+ + +EM+ Y E ++Q +K
Sbjct: 2338 SLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEK 2397
Query: 1337 RISELEEAISILTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVL 1492
I ++ + I + ++ K++ I V E Q+ + ++SK E ++ K++
Sbjct: 2398 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKIN 2457
Query: 1493 ELTSKLEK 1516
S++EK
Sbjct: 2458 ADLSEVEK 2465
Score = 63.9 bits (154), Expect = 3e-07
Identities = 103/563 (18%), Positives = 240/563 (42%), Gaps = 74/563 (13%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 226
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 11081 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 11140
Query: 227 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIV 358
K +D+ I + + + +++++ ++I +
Sbjct: 11141 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 11200
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 538
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 11201 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 11253
Query: 539 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 700
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 11254 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 11309
Query: 701 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 838
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 11310 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 11364
Query: 839 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1015
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 11365 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 11423
Query: 1016 LTHNDELHKEKDDKESIMNDLDHVKAERQVLES--------KVSDMETTYSTLNNELQQK 1171
+ + K +KE++ H++ E++ + S K D+E + +N + Q
Sbjct: 11424 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 11483
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 1330
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 11484 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 11543
Query: 1331 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 1459
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 11544 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11603
Query: 1460 K----EKQDLEKRVLELTSKLEK 1516
K EK+DLEK E+ + ++
Sbjct: 11604 KMIEQEKEDLEKMKSEIMKQRQQ 11626
Score = 63.9 bits (154), Expect = 3e-07
Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 16/514 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALE-YKVADLEAA------ 166
+EN F IA L ++ K DK+ I N+ L+ +Q E + AD+ +
Sbjct: 14413 IENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKADVTSTEKEMYT 14472
Query: 167 -KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXX 343
K T ELE K+ IK D + D+ + D E + L
Sbjct: 14473 EKVTYKTELEDSKEK----IKPDRDSTLELTDTDSAKTDGEREAQTL-----------ET 14517
Query: 344 XXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
V L + EEL E ++K +I +L A+ + + L+ + RS +E
Sbjct: 14518 KVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAK-------KDLQKLKEECRSAEEE 14570
Query: 524 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLER 700
+ E LER ++L E+++ E + +++ + E Q +E K ++
Sbjct: 14571 --KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQT 14620
Query: 701 RASNLDTMDAIHEEELRKEKVDKSA-LTENGEGCEAEKQGPEKTVLDLEPTIPS-LNDAL 874
R+ + ++ +E ++ + +T+ E + K+ + V LE T+ S + +
Sbjct: 14621 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMR 14680
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
+++ V K ++ LE + + E E +E L+ + + + L + D
Sbjct: 14681 DMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKS-RNEETLLQLLHD 14739
Query: 1055 KESIMNDLDHVKAERQ----VLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAV 1222
K+ + N LD E + + ++ +ETT + + +
Sbjct: 14740 KDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKD--------------------- 14778
Query: 1223 KQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLK 1399
K+ +E +L L+ T + E++ G DD NE E K +ELE+ + + KK +
Sbjct: 14779 KENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELED-----SKEKKKPDR 14833
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
D ++ L++ + D +E++ + + VL+LT
Sbjct: 14834 DSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 14867
Score = 63.5 bits (153), Expect = 4e-07
Identities = 113/537 (21%), Positives = 220/537 (40%), Gaps = 46/537 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL--------- 178
+ E T NDE+ EK I + + +L + LE ADLE K +
Sbjct: 8143 NMEKTYEQQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLA 8199
Query: 179 -NDELERKKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXX 334
N+ LER+K D II+ +A +R ++ A A +RD E+ M +
Sbjct: 8200 ENELLEREKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQE 8258
Query: 335 XXXXXXI--------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH 490
+ + L+ ++L EL+K K D + DL ++T +EI+ H
Sbjct: 8259 ASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKH 8312
Query: 491 ---LESKSRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENG 649
+SK+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 8313 EKDTDSKTRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM---- 8367
Query: 650 EGCEAEKQGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEK 811
K V+ +R D M+ I EE+ +E+ + L N + +
Sbjct: 8368 -----------KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDF 8412
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ + +LE ++ D++R++ E + + +L+ E+
Sbjct: 8413 ELLLERTANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EM 8453
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTL 1150
ER++E S + DE K + + + D+ ++ L ++ ++E + L
Sbjct: 8454 ERRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAEL 8512
Query: 1151 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL 1330
+ Q++ E ER+ LE +K + + D+E +E K++ + Q
Sbjct: 8513 AEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKY 8572
Query: 1331 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 1498
K+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8573 KEELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8625
Score = 63.5 bits (153), Expect = 4e-07
Identities = 118/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = +2
Query: 2 QALENKVAD-FEATIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 172
Q LE KV D + T T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 14854 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 14913
Query: 173 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 274
+ + LER+++ + + L ++ +K + Q
Sbjct: 14914 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 14973
Query: 275 ----RDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDL 442
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 14974 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 15030
Query: 443 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 619
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 15031 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 15090
Query: 620 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 733
D K+ +EN E E E L++T ER T D
Sbjct: 15091 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 15149
Query: 734 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 910
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 15150 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 15197
Query: 911 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVK 1090
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 15198 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 15238
Query: 1091 AERQVLESKVSDMETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 1249
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 15239 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 15298
Query: 1250 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 1420
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 15299 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 15358
Query: 1421 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 1513
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 15359 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 15400
Score = 61.6 bits (148), Expect = 1e-06
Identities = 89/490 (18%), Positives = 194/490 (39%), Gaps = 3/490 (0%)
Frame = +2
Query: 98 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 277
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 278 DQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 457
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 458 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 637
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 638 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEK 811
+ E E ++ ++ +T R +L+ + ++E L + K L + E +K
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
D ++ + ++ + L++ +DL + + D Q E
Sbjct: 1916 ------------------DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFME- 1956
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAER-QVLESKVSDMETTYSTLNNELQQ 1168
+ +L+ S ++L + D + N+ D++ ER ++E K+ LN EL+
Sbjct: 1957 KSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELES 2016
Query: 1169 KMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISE 1348
+ LNE+ LE + L + + DLE +++ ++ + + ++Q++ + +
Sbjct: 2017 LKLVKKEVLNEKRLLEDCRISLMRDMQDLE----QMKINLEREKEEMQLQRQSIAEEKDK 2072
Query: 1349 LEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICG 1528
LE + L + +KL D ++ + +L KE E ++ + ++K G
Sbjct: 2073 LESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVG 2132
Query: 1529 ARDGLSTIKE 1558
T K+
Sbjct: 2133 IEKQEITFKD 2142
Score = 61.2 bits (147), Expect = 2e-06
Identities = 118/559 (21%), Positives = 227/559 (40%), Gaps = 54/559 (9%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--------- 160
LE A E L+ EL K+ I ++R LE K L+ K D+E
Sbjct: 7744 LEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYE 7803
Query: 161 ----AAKTTLNDELERKKDDNNAIIKKA------LDKRISDLKADAPQRDQEDD---MNA 301
A + + N +++ D+ NA ++K D+ + K + + E + A
Sbjct: 7804 KQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKARAETERVKQGA 7863
Query: 302 LIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIK--DLVAAEPGKRTVN 475
I + ++ N+ E ++K+K + + DL+ A+ K+
Sbjct: 7864 KIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEE 7923
Query: 476 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG 655
+ +ES+ +E + +E LE + + I + L+ E DGK V+N
Sbjct: 7924 MVKQKIESEREIQQEKKKLQRSEEELEDKMQKIK-REMIELKLLQDETDGKRKDVDN--- 7979
Query: 656 CEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL 835
+ + R+ L+ M A E +K +VD+ L + E K ++
Sbjct: 7980 --------KMRQVARKRDELEKMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE 8031
Query: 836 DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL--EAKNASLTDNQEGHEAEIERKLEA 1009
++ + A +R D + EK+ + R L EA+ AS HE E+ + E
Sbjct: 8032 HMQ------SHAEERAGD--LGEKEPVNTRIQRLIQEAEKASKMAWSTKHEPEMRMQREV 8083
Query: 1010 S----NLTHND----------ELHKEKDDKESIMNDLDHVKAERQVLE-------SKVSD 1126
S ++ D E+ ++ + +++ + ER LE + +
Sbjct: 8084 SVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKN 8143
Query: 1127 METTYSTLNNELQ---QKMDDNEAFLN-ERDGLEAVKQGLE--KRVLDLEATIHDIEMKT 1288
ME TY N+E+Q Q+++ ++ L+ ER+ LE + LE K+++ L+ + K
Sbjct: 8144 MEKTYEQQNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALD------KQKL 8197
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILT-DKAKKLLKDINIWLSEVTELQEDLNKESKE 1465
+++ E EK + K I LE T ++A + + E+ + E L+ E +
Sbjct: 8198 LAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQ 8257
Query: 1466 KQDLEKRVLELTSKLEKCI 1522
+ + +++EL +++K I
Sbjct: 8258 EAS-KNQMVELKRQIDKLI 8275
Score = 60.8 bits (146), Expect = 2e-06
Identities = 117/551 (21%), Positives = 209/551 (37%), Gaps = 81/551 (14%)
Frame = +2
Query: 56 DELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK---TTLNDELERKKDD--NN 214
++LL E +K+ ND + E K+ ALE + D+ K +L +E+ K+ + N
Sbjct: 13819 NDLLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNK 13878
Query: 215 AIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
K + DL+ R Q+ +++ I ++LE
Sbjct: 13879 ETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR----------NDLESMK 13928
Query: 380 LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK---EHFLREEEDEV 550
+L EE ++ +D+ P K + LE + +K EH +E E
Sbjct: 13929 TLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKERE--- 13985
Query: 551 LERSASNLAIMKAIRE--------EELRKEKDGKSALVENGEGCEAE----KQGLEKTVL 694
E N I+K+ E E ++E GK A +E+ E A+ ++ V
Sbjct: 13986 -EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 14044
Query: 695 ERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
+ ++ + E EL+ + K+ L E EAEK E + L+ + D
Sbjct: 14045 TEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDI 14104
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL---------------- 1003
+ + +E+ LEK S+L + L + + + E+ER L
Sbjct: 14105 MTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIES 14160
Query: 1004 ----------EASNLTHNDELHKEK----DDKESIMNDLDHVKAER-------QVLESKV 1120
E L E+ E+ DK I + +H++ E+ L+ ++
Sbjct: 14161 EKQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEI 14220
Query: 1121 SDMETTYSTLNNELQQKMDDNEAF-----LNERDGLEAVKQGLEKRVL-----------D 1252
+ LN E++ K + E + D L+ L + ++
Sbjct: 14221 KRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQ 14280
Query: 1253 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 1432
L+ T D E +T D+ +T ++R LEE ++ T K ++K + SEV E
Sbjct: 14281 LKTTSRDAETQTSLDE-----ITKTDERRQRALEETVA-TTAKQPIVIKLEDTLTSEVQE 14334
Query: 1433 LQEDLNKESKE 1465
+++ LN E KE
Sbjct: 14335 MRDHLNNEIKE 14345
Score = 60.5 bits (145), Expect = 3e-06
Identities = 112/543 (20%), Positives = 217/543 (39%), Gaps = 48/543 (8%)
Frame = +2
Query: 14 NKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN-DEL 190
+K+ + +A + EL K D K ++D LE + + D ++ L E+
Sbjct: 8272 DKLIELKADLLQQQTELKKTKADLKQQMDD---LEKTRSEILKHEKDTDSKTRELELIEI 8328
Query: 191 ERKKDDNNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXXIV 358
+R+KDD I+K L+KR + L+++ ++D + M +I
Sbjct: 8329 QRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANAT 8388
Query: 359 SNLE---VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSR 508
+ + IL +Q + D +TA ++D +A +R V E+V + R
Sbjct: 8389 EEINRERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVR 8447
Query: 509 SLK---EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQG 676
+LK E + + + E+ E+ I + I++ ++R+ G +E + E +
Sbjct: 8448 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 8507
Query: 677 LEKTVLERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT 829
+ + E++ + +H+E E+ +EK D E E +++ E T
Sbjct: 8508 MRAELAEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFT 8567
Query: 830 -VLDLEPTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
+ + + S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +
Sbjct: 8568 DIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-K 8626
Query: 998 KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 1177
K E DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8627 KGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDL 8686
Query: 1178 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------ 1339
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8687 FRSELQRQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKI 8743
Query: 1340 ----------ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
I + + IL D + +D + E +L E D+E+ V
Sbjct: 8744 RFDIANARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLV 8799
Query: 1490 LEL 1498
LE+
Sbjct: 8800 LEV 8802
>ref|XP_005159738.1| PREDICTED: titin isoform X1 [Danio rerio]
Length = 15746
Score = 101 bits (251), Expect = 2e-18
Identities = 132/600 (22%), Positives = 266/600 (44%), Gaps = 39/600 (6%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRN--------ILEAAKQALEYKVADL 157
Q +E A + +N+ L+ E + K ++N++N +++ K LE + DL
Sbjct: 6214 QRVEEMTAQIQKDRDKINN-LIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDL 6272
Query: 158 EAAKTTL---NDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXX 316
E ++ L ++LE++K++ A I+K L+K ++ + + + QE+ MN
Sbjct: 6273 EKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQ----- 6327
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKRTVNEIV 484
+ L+ I L +EL+KEK+ ++ L + + + +N+I+
Sbjct: 6328 ---------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIM 6378
Query: 485 SHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
++++ + L K+ EE+ + +E+ N+ + +E+L+ K K + E E
Sbjct: 6379 ETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLE 6438
Query: 662 AEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTENGEGCEAEKQGPEK 826
K LE+ + R +T + EEL+KE+ D + L E+ + EK ++
Sbjct: 6439 QMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED---TKREKNSLDE 6495
Query: 827 TVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLE 1006
+ E ++ L Q++ + K+ + K+ D+E + D E E+E+ L+
Sbjct: 6496 MKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DKIRLREDELEQ-LQ 6546
Query: 1007 ASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
A E+HK++ + E + +++ ER + V D+++ +L+ + + D E
Sbjct: 6547 A-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE 6596
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI 1342
AF NE++ L+ +K LE+ ++E T H+ EM + N KQ K ++
Sbjct: 6597 AFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKV 6656
Query: 1343 ------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
E+E+ + K L +D+ + ++ L+E+ NK + K LE+ E+ S
Sbjct: 6657 MIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-S 6715
Query: 1505 KLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 1684
K+++ R L + A + E L + RK LD K + +++
Sbjct: 6716 KIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVLDKIKVANESTLAD 6766
Score = 99.8 bits (247), Expect = 5e-18
Identities = 131/591 (22%), Positives = 260/591 (43%), Gaps = 87/591 (14%)
Frame = +2
Query: 5 ALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTT--- 175
A+ V D + + +L+ +L + K D++ N+R +L+ K L+ K ++E K
Sbjct: 4865 AIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQH 4924
Query: 176 -------LNDELERKKDDNNAIIKKA--LDKRISDLKADAPQRDQ--EDDMNALIXXXXX 322
+ ++++++D N +I++ D ++++K + ++ + E D + L
Sbjct: 4925 DRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHD 4984
Query: 323 XXXXXXXXXXIVSNLEVNILILHEELQKEKDDK-------TALIKDLVAAEPGKRTVNEI 481
NLE I E+QKE++D T I D+ E + +
Sbjct: 4985 LEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDE 5044
Query: 482 VSHLESKSRSLKEHFLREEEDEVLERSASNLA-------------IMKAIREEELRKEKD 622
+ L+++ ++L++ +E+E + +RS +L IM+ ++ E + +KD
Sbjct: 5045 LDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKD 5104
Query: 623 GKSALVENGEGCEAEKQG----------------LEKTVLERRASNLDTMDAIHEEELRK 754
K E + E EK L+K VLE S L+ M EL +
Sbjct: 5105 -KEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKI----ELER 5159
Query: 755 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 934
E V+ + E + E+Q EK L+ L + +++ + K A E +D
Sbjct: 5160 EAVEIRKIKEE---IQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLAD 5216
Query: 935 LEAKNASLTDNQEG---HEAEIERKLEASNLTHND------ELHKEKDDKESIMNDLDHV 1087
+ + ++L + +E ++E K E L ++ E+HK++ + E + ++
Sbjct: 5217 ILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEK---EKINI 5273
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE--- 1258
++ER + V D++ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 5274 ESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIK 5333
Query: 1259 -ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AK 1387
T HD +++ +D+ N E+ L ++ ++EE I SI +DK +
Sbjct: 5334 LETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLE 5393
Query: 1388 KLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 1516
K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 5394 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 5444
Score = 99.4 bits (246), Expect = 6e-18
Identities = 124/547 (22%), Positives = 230/547 (42%), Gaps = 48/547 (8%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 217
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 4764 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 4823
Query: 218 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEE 397
K+ R+ + + + Q + + V +L+ + L +
Sbjct: 4824 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 4883
Query: 398 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 553
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 4884 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 4936
Query: 554 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 706
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 4937 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 4996
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 865
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 4997 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 5056
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 5057 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 5116
Query: 1040 KEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
KEK D ++S+ DL +K ++QVLE + S +E L E + E NER
Sbjct: 5117 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 5176
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 1369
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 5177 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 5233
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 1525
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 5234 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 5293
Query: 1526 GARDGLS 1546
RD S
Sbjct: 5294 LDRDAES 5300
Score = 94.0 bits (232), Expect = 2e-16
Identities = 133/541 (24%), Positives = 243/541 (44%), Gaps = 54/541 (9%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 5824 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 5883
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5884 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5922
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5923 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5980
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 718
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 5981 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 6040
Query: 719 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 883
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 6041 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 6089
Query: 884 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1057
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 6090 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINI 6146
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
ES ER + V D++ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 6147 ES----------ERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 6196
Query: 1238 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 1363
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 6197 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 6256
Query: 1364 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 1513
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 6257 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 6316
Query: 1514 K 1516
+
Sbjct: 6317 E 6317
Score = 92.8 bits (229), Expect = 6e-16
Identities = 122/541 (22%), Positives = 232/541 (42%), Gaps = 42/541 (7%)
Frame = +2
Query: 2 QALENKVADFEATIATLN---------DELLNEKDDK-----KCIVNDRNILEAAKQALE 139
Q +E K A + +N D +LNE D K I +D+++LE + LE
Sbjct: 4257 QRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLE 4316
Query: 140 YKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXX 319
++L AK L + E ++ D + KK + + + ++K Q Q+ D
Sbjct: 4317 KTRSELARAKENLETQREIERKDIEKM-KKNISREMHEIKHQEEQMKQKQDE-------- 4367
Query: 320 XXXXXXXXXXXIVSNLEVNILILHEELQKEKDD--KTALIKDLVAAEPGKR--TVNEIVS 487
+ L+ I L +EL+KEK+ K DL +E K+ +N+I+
Sbjct: 4368 ------------LDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIME 4415
Query: 488 HLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 664
++++ + L K+ EE+ + +E+ + + +E+L+ K K + E E
Sbjct: 4416 TMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEE-----EK 4470
Query: 665 EKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLE 844
K K LER A +E+RK K + T+N E+Q EK L+
Sbjct: 4471 SKLKQMKIELEREA-----------DEIRKVKEE----TQN------ERQIFEKMTEALK 4509
Query: 845 PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG---HEAEIERKLEASN 1015
L++ +R + K A E +D+ + ++L + +E ++E K E
Sbjct: 4510 KEREDLSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIR 4569
Query: 1016 LTHND------ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 1177
L E+HK++ + E + +++ ER + V D+++ +L+ + +
Sbjct: 4570 LREEKLKQLQAEIHKQQSETEK---EKSNIERERAAIIKDVEDLQSKIISLDRDAESLKL 4626
Query: 1178 DNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIEMKTGKDDDYNEA---------- 1315
D EAF NE++ L+ +K LE+ ++E T H+ + D+ E
Sbjct: 4627 DREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNK 4686
Query: 1316 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 1495
K+ ++++ E+E+ + K L K++ + + ++E+ NK + K +LEK E
Sbjct: 4687 NKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADE 4746
Query: 1496 L 1498
+
Sbjct: 4747 I 4747
Score = 91.3 bits (225), Expect = 2e-15
Identities = 138/568 (24%), Positives = 250/568 (44%), Gaps = 63/568 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 166
+ LE+ + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3388 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3447
Query: 167 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 313
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3448 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3501
Query: 314 XXXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 475
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3502 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3545
Query: 476 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3546 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3600
Query: 653 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 808
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3601 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3654
Query: 809 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 979
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3655 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQ 3714
Query: 980 -EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 1156
+AEI ++ E+ KEK + ES ER + V D++ +L+
Sbjct: 3715 LQAEIHKQQR--------EIEKEKSNIES----------ERAAIIKIVEDLQHKIISLDR 3756
Query: 1157 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIE-------MKTGKDDD 1303
+ + D EAF NER+ L+ +K LE+ ++E T HD + T + D
Sbjct: 3757 DAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDK 3816
Query: 1304 YNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLNKE 1456
N ++T L ++ ++EE I SI +DK +K ++ SE+ +++EDL K+
Sbjct: 3817 INNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQ 3876
Query: 1457 --------SKEKQDLEKRVLELTSKLEK 1516
KE++DLEK +T ++ +
Sbjct: 3877 KENTLAEIQKEREDLEKMNENITIEMHE 3904
Score = 91.3 bits (225), Expect = 2e-15
Identities = 102/535 (19%), Positives = 239/535 (44%), Gaps = 32/535 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 5073 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5132
Query: 188 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXXI 355
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 5133 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5192
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 529
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 5193 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5252
Query: 530 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 667
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 5253 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 5311
Query: 668 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
K+ L+ KT LER A ++ + E + +++V++ A + E E D+
Sbjct: 5312 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 5369
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLT 1021
+ N ++ + + ++K LEK DLE + L +E E + E L
Sbjct: 5370 --VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA----- 5422
Query: 1022 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
E+ KE++D E+I ++ +K + + + K +++ + + N Q+ + E
Sbjct: 5423 ---EIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5479
Query: 1190 FLNERDGLEAVKQGLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEA 1360
+ +R L+ + L+K+ + D+ T+ + + KD + E +KQ ++K ++++
Sbjct: 5480 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 5539
Query: 1361 ISILTDKAKKLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
L + KK+ ++ E +L++ +L +E+ E +++ +LEK
Sbjct: 5540 RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 5594
Score = 89.4 bits (220), Expect = 6e-15
Identities = 114/525 (21%), Positives = 236/525 (44%), Gaps = 44/525 (8%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE K LE YKV DLE K E++++
Sbjct: 5368 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKE 5427
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5428 REDLEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5466
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5467 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5524
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT------VLER 700
+ + +E+ N+ + +E+ +K K K E E K LE+ + E
Sbjct: 5525 QKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEE 5584
Query: 701 RASNLDTMDAIHEEELRKE----------KVDKSALTEN---GEGCEAEKQGPEKTVLDL 841
+ ++ + EE +R++ K +K L E E A+ Q + + ++
Sbjct: 5585 TQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEM 5644
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNL 1018
I L + + + ++ + L+K ++++ + + + + E+E + E N+
Sbjct: 5645 RENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNM 5704
Query: 1019 THNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
EL K+ +D E I+ + + + +R++L V +++ L + ++ D E
Sbjct: 5705 M--TELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 5762
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS 1366
AF NE++ ++ +K L+ + ++E I+++T D E ++K ++ I
Sbjct: 5763 AFENEKEAMKQMKTDLQIQADEIE----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE 5818
Query: 1367 ILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLEL 1498
T++ +L + N + E + +Q D + KE+ +LEK EL
Sbjct: 5819 -ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSEL 5862
Score = 87.8 bits (216), Expect = 2e-14
Identities = 122/538 (22%), Positives = 233/538 (43%), Gaps = 24/538 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E++ E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2554 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2613
Query: 182 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 340
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2614 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2669
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 520
I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2670 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2722
Query: 521 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 682
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2723 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 2782
Query: 683 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 832
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 2783 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 2841
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1009
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 2842 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 2897
Query: 1010 SNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
++++ +++L KE+ ++E I N +K E LE ++ NNELQ+K+ +
Sbjct: 2898 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 2951
Query: 1190 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 1369
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 2952 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3001
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 1543
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3002 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3052
Score = 85.9 bits (211), Expect = 7e-14
Identities = 116/534 (21%), Positives = 238/534 (44%), Gaps = 34/534 (6%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLND 184
K+ + + +A L+ EL KD+ + I +R+ +E + L ++ +E + D
Sbjct: 9728 KMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQD 9787
Query: 185 ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSN 364
+ ++ +I +K + +I + + Q +QE N L I N
Sbjct: 9788 KQNHLEEKELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELN 9844
Query: 365 LEVN------ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK 502
+ N + + EL+ EK D K + L E K + ++ L+SK
Sbjct: 9845 KQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSK 9904
Query: 503 -SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
++ KE + ++R + + + + + + K+ L E E + E++ L
Sbjct: 9905 REQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKL 9964
Query: 680 E--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E K +++ A NL+ + + + K ++ ++ L E CE ++ E+ D+E I
Sbjct: 9965 EEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQI 10024
Query: 854 PSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EAS 1012
+ +A L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +
Sbjct: 10025 QNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKA 10084
Query: 1013 N--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL---QQKMD 1177
N L D+L KEK+D N LD ++ E Q + +++ NE+ QQ+++
Sbjct: 10085 NEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLE 10144
Query: 1178 DNEAFLNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 1354
++ +NE G LE ++ EK+ +E + +M E++ L + SELE
Sbjct: 10145 ESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELE 10193
Query: 1355 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ + + + KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 10194 KDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10247
Score = 85.5 bits (210), Expect = 9e-14
Identities = 103/492 (20%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = +2
Query: 71 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 238
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2236 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2293
Query: 239 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDD 418
+R+++++ + +++ D+ ++E + IL+ EL+K K+
Sbjct: 2294 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2341
Query: 419 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 598
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2342 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2395
Query: 599 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 778
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2396 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2453
Query: 779 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 958
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2454 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2506
Query: 959 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETT 1138
+ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E + +E
Sbjct: 2507 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2564
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 1309
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2565 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2619
Query: 1310 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 1453
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2620 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2679
Query: 1454 --ESKEKQDLEK 1483
SK+K+DLEK
Sbjct: 2680 LTLSKQKEDLEK 2691
Score = 82.4 bits (202), Expect = 7e-13
Identities = 111/556 (19%), Positives = 242/556 (43%), Gaps = 54/556 (9%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL----------- 157
EN + E + +++ N ++ K + +R ++ KQ L+ + DL
Sbjct: 10007 ENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENV 10066
Query: 158 EAAKTTLNDELERKKDDNNAIIKKA--LDKRISDL-----KADAPQRDQEDDMNALIXXX 316
E +K +L++E + + N I+++ L+K D+ K D Q + +++ A+
Sbjct: 10067 EMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIK 10126
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEE------LQKEKDDKTALIKDL-VAAEPGKRTVN 475
LE ++ ++EE ++ + + + I+++ V A+ ++ ++
Sbjct: 10127 YELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELD 10186
Query: 476 EIVSHLESKSRSLKEHFLREEEDE-VLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I S LE + + + D ++E+ ++L MK+ + ++ +D +S L + +
Sbjct: 10187 QIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIK 10246
Query: 653 GCEAEKQGLEKT--VLERRASNLDTMD---AIHEEELRKEK---VDKSALTENGEGCEAE 808
EK +EK ++ER + ++ + +EEL E+ VD+ L CE E
Sbjct: 10247 EANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQ---CETE 10303
Query: 809 KQGPEKTVLDLEPTIPSLNDAL-------QRD-------LDRVMAEKQALEKRCSDLEAK 946
Q + + ++E + + + L QRD ++ +K+ LEK + + +
Sbjct: 10304 LQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQ 10363
Query: 947 NASLT---DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLES- 1114
L D E EI K ++ + + KE + + ++ ER+ LE
Sbjct: 10364 KQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEV 10423
Query: 1115 --KVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKT 1288
K+ +M+T ++E+ QK+++ L+ +++ + K EA ++M
Sbjct: 10424 NGKIIEMKTKAELEHHEINQKIEE----------LQTLQEQIMKEKEKAEAMTIKLKM-- 10471
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEK 1468
E++ L + SEL + + + KKL DI + E +L++ ++ +K
Sbjct: 10472 ---------EREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10522
Query: 1469 QDLEKRVLELTSKLEK 1516
Q++EK EL +K+++
Sbjct: 10523 QEMEKERSELDNKIQQ 10538
Score = 82.0 bits (201), Expect = 1e-12
Identities = 117/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N ++ E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 9412 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 9471
Query: 188 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 343
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 9472 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 9530
Query: 344 XXXIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 514
L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 9531 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 9585
Query: 515 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 9586 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9645
Query: 680 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9646 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9704
Query: 854 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1030
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9705 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 9759
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 1210
E H+ + + + + + ++ + Q+++ K + +E ++ + ++ N F E++
Sbjct: 9760 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 9819
Query: 1211 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 1390
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 9820 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 9865
Query: 1391 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 1516
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 9866 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 9907
Score = 81.3 bits (199), Expect = 2e-12
Identities = 121/518 (23%), Positives = 225/518 (43%), Gaps = 20/518 (3%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + E +L+ +DDK + NDR+ E LE K
Sbjct: 9219 QDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELK-----------R 9267
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+EL R+ +D + +K L +R D + +RD E+ AL
Sbjct: 9268 EELVRETED---LERKILQQREQD---EMAKRDIENQTEAL------------------E 9303
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
++V+IL E KE ++ V +E K + + L+S+ L+ EE+
Sbjct: 9304 VMKVDILKKRNEFAKEMEN--------VHSERQKLLL--LQGALQSQESELENRVFMEEQ 9353
Query: 542 DEVLERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
+ + A K + E E + E++ L+E + E E+ + K +E+ +L
Sbjct: 9354 KHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR-EKEQLEISKNQIEQEKKDL 9412
Query: 716 DTMDAIHE---EELRKEKV----DKSALTENGEGCEAEKQGPEKTVLDLE---PTIPSLN 865
M + E E LR EK +K+AL + + + K DLE I
Sbjct: 9413 QNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEK 9472
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
++ + R+ ++ ++K S+L+ ++ +E ++E +++ +E+
Sbjct: 9473 KRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIE 9532
Query: 1040 KEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 1219
KE + DL++ KAE Q E K D+ ++ ++Q+K + + L++ +
Sbjct: 9533 KESQRLQDATIDLENAKAEIQRQEDKFEDI------IDIKIQEKEREIKIQLDKE--TKR 9584
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKK 1390
+ + +E +V DLE + D++ + + +D E EKQ LK+ ELE+ + LT + ++
Sbjct: 9585 LSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQE 9644
Query: 1391 LLKDINIWLSEVTELQEDLNKES---KEKQDLEKRVLE 1495
++ N ++ +L EDL KE+ KEK LEK +E
Sbjct: 9645 TEEERNNLMALKNQL-EDLRKENEIVKEKLTLEKSNIE 9681
Score = 80.9 bits (198), Expect = 2e-12
Identities = 111/536 (20%), Positives = 231/536 (43%), Gaps = 46/536 (8%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 12105 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 12164
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 12165 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 12224
Query: 362 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 12225 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 12284
Query: 509 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 664
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 12285 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 12339
Query: 665 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 811
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 12340 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 12399
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 12400 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 12459
Query: 992 --ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 12460 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 12519
Query: 1154 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 1318
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 12520 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 12575
Query: 1319 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 1480
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 12576 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12628
Score = 80.1 bits (196), Expect = 4e-12
Identities = 94/521 (18%), Positives = 225/521 (43%), Gaps = 46/521 (8%)
Frame = +2
Query: 92 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 244
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 11773 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 11832
Query: 245 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEEL 400
I ++K ++++E+ M A + I S LE + E
Sbjct: 11833 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 11886
Query: 401 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 580
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 11887 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 11945
Query: 581 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 706
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 11946 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 12005
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 12006 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 12061
Query: 887 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1033
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 12062 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 12121
Query: 1034 LHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGL 1213
+ KEK+ +E V+ ER+ +E S +E S +++E ++ DD + E++ L
Sbjct: 12122 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 12181
Query: 1214 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 1393
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 12182 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 12240
Query: 1394 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 12241 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 12281
Score = 79.3 bits (194), Expect = 6e-12
Identities = 122/575 (21%), Positives = 250/575 (43%), Gaps = 74/575 (12%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K+ E T +++ EK+ ++ V R +E K+ L+ + LE ++ ++ E
Sbjct: 11550 ETKIKIIEMKTKTEPEKIKKEKEKEEEEVM-RAKVEMKKEELDQIKSQLERVRSEIDHEQ 11608
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 11609 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQ 11668
Query: 362 NLEV-------NILILHEEL----QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V +I + EEL QK D++ ++++ + + E+ ++ +
Sbjct: 11669 KLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKE 11728
Query: 509 SLKE---HFLREEED-------------EVLERSASNLA-----------IMKAIREE-- 601
+LKE H +E+E+ E LE+ ++++ ++K REE
Sbjct: 11729 TLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEIN 11788
Query: 602 ----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE--KV 763
+L++ D A V + + KQ K + E R S +T I E + + E K+
Sbjct: 11789 HKWTQLQQRIDEFDAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKI 11845
Query: 764 DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEA 943
K E E A+ + ++ + ++ + + + + ++ +K+ +E+ DLE
Sbjct: 11846 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 11905
Query: 944 KNASLTDNQEGHE---AEIERKLEASNLTHND-ELHKE---------KDDKESIMNDLDH 1084
+ + ++ E +E+E K+ + + D E KE ++ K I +
Sbjct: 11906 MKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEE 11965
Query: 1085 VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEAT 1264
+ ERQ + + + S L NE ++ + NE ER+ L+ ++ LEK ++++
Sbjct: 11966 LDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI 12025
Query: 1265 IHDIEMKTGKDD-----DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVT 1429
E + K+D + +KQ L+ + LE+ + K K+L + I+ + ++V+
Sbjct: 12026 TE--ETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 12083
Query: 1430 -ELQEDLNKESKEKQD------LEKRVLELTSKLE 1513
+ +EDL KE + K+D + +LE+ +K E
Sbjct: 12084 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAE 12118
Score = 79.0 bits (193), Expect = 8e-12
Identities = 121/570 (21%), Positives = 237/570 (41%), Gaps = 67/570 (11%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
LE AD + +++L K +++ + R + K+ LE ++ ++ ND
Sbjct: 1153 LEMMKADLLRQKEDIENQMLAAKSERQQMEVMRTEILKQKEDLEERLEEVIKE----NDR 1208
Query: 188 LERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSN 364
+E+ ++D NNA+ K +D+ D++ QE A++ I S
Sbjct: 1209 VEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAIKS- 1265
Query: 365 LEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEED 544
+ L L +QKE+ + K+++ E K +N+I +++ +E ++ E+
Sbjct: 1266 YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKLHEE 1322
Query: 545 EVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------EKTV 691
E E +++ R+ + KEK+ G A+ + KQ L EK+
Sbjct: 1323 EK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSEKSK 1381
Query: 692 LERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ 814
LE + AS D +I E + +++ ++ + C E+Q
Sbjct: 1382 LEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTMERQ 1441
Query: 815 GPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 937
E +T D+E + L++ D + K ++K DL
Sbjct: 1442 MAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDL 1501
Query: 938 EAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAERQV 1105
+ + A + +E E+E+ + N D E K E D K ++ + ++++A+R++
Sbjct: 1502 QTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQRKM 1561
Query: 1106 LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEM- 1282
+E + +E L E +ER +E + L++ +LE HD++
Sbjct: 1562 MEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQL 1621
Query: 1283 -----KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWLSEV 1426
+ KD ++ E + TL K S++ E IS L + K +++ I I ++
Sbjct: 1622 QTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDL 1681
Query: 1427 TELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++Q DLN++ KE QD++ V S+L+K
Sbjct: 1682 QQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1711
Score = 78.6 bits (192), Expect = 1e-11
Identities = 115/572 (20%), Positives = 245/572 (42%), Gaps = 91/572 (15%)
Frame = +2
Query: 56 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 193
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 6470 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 6529
Query: 194 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 331
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6530 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 6589
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 499
N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 6590 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6646
Query: 500 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 676
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6647 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6706
Query: 677 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 808
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6707 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 6766
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 988
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 6767 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 6826
Query: 989 IERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
+ E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 6827 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 6884
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 1294
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 6885 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 6944
Query: 1295 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 1420
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 6945 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 7000
Query: 1421 EVTELQEDLNKESKE------KQDLEKRVLEL 1498
E+ + + L K SKE K + EK+ ++L
Sbjct: 7001 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 7032
Score = 77.8 bits (190), Expect = 2e-11
Identities = 109/519 (21%), Positives = 218/519 (42%), Gaps = 22/519 (4%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKC-----------IVNDRNILEAAKQALEYKVADLEAAKT 172
+ I+ +++ NEK+ K + ++ ++ K +E + A + K
Sbjct: 4103 EMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQ 4162
Query: 173 TLNDELERKKDDNNAIIKKAL-DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXX 349
+ EL++K +D +K+ L +K + + ++ ++D ED L+
Sbjct: 4163 NMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDRE 4222
Query: 350 XIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFL 529
+ EV + + +LQ + D+ + K + + ++ V E + ++ K R
Sbjct: 4223 AFGNEKEV-LKQMKTDLQIQADE---IEKIKLETQHDRQRVEEKTAQIQ-KDRD------ 4271
Query: 530 REEEDEVLERSASNLAIMKAIR--EEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLE 697
E + ++E + ++ + + R EE+++ + K L E E+ LEKT L
Sbjct: 4272 -EINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDML-------EKERHNLEKTRSELA 4323
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQ 877
R NL+T I +++ K K + S + E + + + + L+ I +L L+
Sbjct: 4324 RAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELE 4383
Query: 878 RDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKD 1051
++ + +M + L+ R S+L+ + ++ D E + E ++ K + E+ KEK
Sbjct: 4384 KEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKH 4443
Query: 1052 D----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 1219
D ++S+ DL +K ++QV+E + S ++ L E + E NER E
Sbjct: 4444 DFDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEK 4503
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 1399
+ + L+K DL D + K D+ A + TL
Sbjct: 4504 MTEALKKEREDLS---EDAKRKNQVLDEMKVANESTLA---------------------- 4538
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
DI L E + LQE SK+ +D+E + ++ + EK
Sbjct: 4539 DI---LRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4574
Score = 77.8 bits (190), Expect = 2e-11
Identities = 108/524 (20%), Positives = 230/524 (43%), Gaps = 31/524 (5%)
Frame = +2
Query: 38 TIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL---NDELERKKDD 208
T+ + L EK++ K I + K+ LE D++ L D LE++K+D
Sbjct: 10615 TLKEMEAHLEKEKEEMKSITEETR---RQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKED 10671
Query: 209 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILIL 388
N + L +RI + A ++ +ED I + + +
Sbjct: 10672 INHEWTQ-LQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDI 10730
Query: 389 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE--VLERS 562
+E +KE++++ +K E + ++ I S L+ + RS +H ++ D+ ++E+
Sbjct: 10731 KKEKEKEEEEEEMRVK----VEMDGKELDRIKSELK-RERSEIDHEQKKLNDDKKIIEQE 10785
Query: 563 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE 742
NL MK+ ++ ++ ++ +S L + EK +E + + ++ + HE
Sbjct: 10786 KQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEI 10845
Query: 743 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 922
+ +KE++D E+Q + D + + LQ + +R+ + ++K
Sbjct: 10846 QFQKEELD------------IERQ----KIADEQDLLIQNKSELQNENERIRNLNEIIKK 10889
Query: 923 RCSDLEAKNASLTDNQEGHEAEIE--RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAE 1096
L+ A L +E ++ E R+L+ + +++K+ D +MN D ++ E
Sbjct: 10890 ERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKD---LMNQRDLLEQE 10946
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IH 1270
R+ + K +LQQ++D+ +A ++++ + K+ G+++ LE T +
Sbjct: 10947 REEINHKWK-----------QLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 10995
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL------------------ 1396
IEMKT + + + EK+ + E EE I ++ + +K L
Sbjct: 10996 VIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQ 11055
Query: 1397 KDINIWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEK 1516
K +N ++ + + +EDL K K++Q +E+ EL +K+++
Sbjct: 11056 KKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQ 11099
Score = 76.6 bits (187), Expect = 4e-11
Identities = 112/520 (21%), Positives = 215/520 (41%), Gaps = 22/520 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA------- 166
+EN F+ IA L + K DK+ I N+ L+ +Q E + + +
Sbjct: 14766 IENITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYD 14825
Query: 167 -----KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 331
KT L D E+KK D ++ +K ++D AD+ + D E + L
Sbjct: 14826 EKVTYKTELEDSKEKKKPDRDSSLK------LTD--ADSAKTDGEREAQTL--------- 14868
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
V L EEL E ++K +I +L A+ + + L+ + RS
Sbjct: 14869 --ETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAK-------KDLQKLKEECRS 14919
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KT 688
+E + E LER ++L E+++ E + +++ + E Q +E K
Sbjct: 14920 AEEE--KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKM 14969
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPS--- 859
++ R+ + ++ ++ +T+ E + K+ + TV LE T+ S
Sbjct: 14970 QIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQ 15029
Query: 860 -LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDEL 1036
+ D+L ++++ V K ++ LE + + E E +E +E + + ++L
Sbjct: 15030 EMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKL 15088
Query: 1037 HKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER 1204
+ DKE + N LD ++ + K++ +ETT + +
Sbjct: 15089 LQLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETTIVLMKKD--------------- 15133
Query: 1205 DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDK 1381
K+ +E +L L+ T + E++ G DD NE EK K +ELE+ +
Sbjct: 15134 ------KENIENELLQLKQTEQEREIQRGTDDTSNEREKYDEKVTYKTELED-----NKE 15182
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
KK +D ++ L++ + D +E++ + + VL+LT
Sbjct: 15183 KKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 15222
Score = 76.3 bits (186), Expect = 5e-11
Identities = 125/547 (22%), Positives = 241/547 (44%), Gaps = 47/547 (8%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT---TLNDE 187
K+AD + + EL NE + I N I++ ++ L+ A LE K ++++E
Sbjct: 10858 KIADEQDLLIQNKSELQNENER---IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEE 10914
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R K+D L+K +D+ +D + + L +
Sbjct: 10915 TRRLKED--------LEKMSTDVNKQ--NKDLMNQRDLLEQEREEINHKWKQLQQRIDEF 10964
Query: 368 EVNILILHEE-LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES---KSRSLKEHFLRE 535
+ + E+ L KEK K +D + E K V E+ + E K KE+ E
Sbjct: 10965 DAQVSKQKEQDLPKEKGMK----EDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEE 11020
Query: 536 EEDE----VLERSASNLAIMKAIREEELRKEKDGKSA-LVENGEGCEAEKQGLEKTV--- 691
EE+E ++E L +K+ E +R E D + L + + E EK+ LEK
Sbjct: 11021 EEEEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEI 11079
Query: 692 ------LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDL 841
+E S LD + I + L K ++KS E E+Q + K LD+
Sbjct: 11080 MKQRQQMEEERSELD--NKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDI 11137
Query: 842 E-PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNL 1018
E I + L ++ ++ E + ++K +++ + +L E EI K E L
Sbjct: 11138 ERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETL------REMEIHLKKEKEEL 11191
Query: 1019 THN-DELHKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 1183
+E + K+D E + D++ H+K +R +LE + ++ + +LQQ++D+
Sbjct: 11192 RSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT----QLQQRIDEF 11247
Query: 1184 EAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDIEMKTGKDDDYN-----EA 1315
+A +++ + +E ++ LE+ R+++++ A + +I + ++D+ E
Sbjct: 11248 DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVEM 11307
Query: 1316 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 1495
E++ L + SEL+ S + + KKL D I E +L++ ++ ++Q +E+ E
Sbjct: 11308 EREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSE 11367
Query: 1496 LTSKLEK 1516
L +K+++
Sbjct: 11368 LDNKIKQ 11374
Score = 75.5 bits (184), Expect = 9e-11
Identities = 110/522 (21%), Positives = 225/522 (43%), Gaps = 35/522 (6%)
Frame = +2
Query: 5 ALENKVADFE---ATIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEA 163
A + + DFE I N EL ++++ K + + R LE + + +V +
Sbjct: 7211 AFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITN 7270
Query: 164 AKTTLND---ELERKKDD-----------NNAIIKKA--LDKRISDLKADAPQRDQEDDM 295
+L+ EL + ++D N I+ + LD+R SD+ D Q++ +D M
Sbjct: 7271 ENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQKEVDDLM 7328
Query: 296 NALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVN 475
+ ++N+E L + + + K D +L + A E + +N
Sbjct: 7329 D--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLN 7374
Query: 476 EIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E +E + L ++ ++D++ ++R NL + K + E ++ + K +L
Sbjct: 7375 EEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAI 7434
Query: 653 GCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ 814
G + +EK E+ ++E A+ LD + E + +E++D++ +
Sbjct: 7435 GFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLF 7494
Query: 815 GPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 994
EKT DL+ T +N D + + ++ L K E E
Sbjct: 7495 QEEKT--DLQKTKEEIN----YDREEIYRQRTELNK-------------------EKETL 7529
Query: 995 RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKM 1174
+++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + + E +
Sbjct: 7530 KQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELA 7586
Query: 1175 DDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ---TLKKRIS 1345
D E NE+D L+ ++ ++K + +L+ E + + N+ +Q +K +
Sbjct: 7587 RDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTEEIKLKND 7640
Query: 1346 ELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 1465
L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7641 SLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7682
Score = 75.5 bits (184), Expect = 9e-11
Identities = 105/540 (19%), Positives = 219/540 (40%), Gaps = 57/540 (10%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 13424 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13473
Query: 221 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEV 373
+ AL+K + DL+ + +++NAL+ E
Sbjct: 13474 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 13514
Query: 374 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 532
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 13515 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 13573
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 13574 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13627
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 892
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13628 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13687
Query: 893 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1042
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13688 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13746
Query: 1043 EKDDKESIMNDL----------------------------DHVKAERQVLESKVSDMETT 1138
EKD E I DL D + + + L S +D+E
Sbjct: 13747 EKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQ 13806
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 13807 AKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDLT 13848
Query: 1319 KQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL ++
Sbjct: 13849 LQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQL 13908
Score = 74.3 bits (181), Expect = 2e-10
Identities = 122/611 (19%), Positives = 247/611 (40%), Gaps = 64/611 (10%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELER 196
+V + L E+ ++ K ++++ I ++ Q L + + L E+E
Sbjct: 8813 EVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIEN 8872
Query: 197 KKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVN 376
K D K L+K ++L + Q+++E L ++E++
Sbjct: 8873 TKRD-----KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEIS 8925
Query: 377 ILILHEEL-----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES-------- 499
++ E+ QK K++ + ++L+ + +N V HL
Sbjct: 8926 RELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQ 8985
Query: 500 --KSRSLKEHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDG 625
K ++ EH E + +++LE+ L +++I E L+K +D
Sbjct: 8986 YIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED- 9044
Query: 626 KSALVENGEGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGE 793
+ + E EKQ E + L+R+ +++ I E++ K K+D E
Sbjct: 9045 ---MEKEKENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSA 9100
Query: 794 GCEAEKQGPEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEA 943
E E + E DLE SLNDA LQ+ + + EK+ +E+ ++
Sbjct: 9101 AFEKEHKRLENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKT 9160
Query: 944 KNASLTDNQE-----------GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD-HV 1087
+ + +E GHE ++++K E + D+L ++ + + + DL +
Sbjct: 9161 ERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKL 9214
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 1267
+ +RQ +E ++MET +L+ ++ DD N+RD E LE + +L
Sbjct: 9215 QMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRET 9274
Query: 1268 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 1447
D+E K + + +E K+ ++ + LE + K + K++ SE +L
Sbjct: 9275 EDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQ 9334
Query: 1448 NKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGF 1624
++ +LE RV +E L++ + + E MS+ + + + L++
Sbjct: 9335 GALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEEL 9391
Query: 1625 SRKTSPLDITK 1657
R+ L+I+K
Sbjct: 9392 QREKEQLEISK 9402
Score = 73.9 bits (180), Expect = 3e-10
Identities = 115/530 (21%), Positives = 227/530 (42%), Gaps = 26/530 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + DF+ + +L+++L K K+ I +++ L+ K LE + ++ K
Sbjct: 4436 QEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQ 4495
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIV 358
+E + + + +AL K DL DA +++Q D+M V
Sbjct: 4496 NERQIFEK-----MTEALKKEREDLSEDAKRKNQVLDEMK-------------------V 4531
Query: 359 SNLEVNILILHEE--LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR 532
+N IL E LQ+ +++ + +D+ + R E + L+++ + +
Sbjct: 4532 ANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEK 4591
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE--KTVLERRA 706
E+ + ER+A + ++ ++ + + ++D +S ++ E E EK+ L+ KT LER A
Sbjct: 4592 EKSNIERERAAI-IKDVEDLQSKIISLDRDAESLKLDR-EAFENEKEELKQMKTELEREA 4649
Query: 707 SNLDT--MDAIHEEELRKEKV---------DKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
++ ++ HE + +E ++ L +N E + +KQ EK D++ +
Sbjct: 4650 DEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSR 4709
Query: 854 PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDE 1033
SL+ ++L + +KQ +E+ + LE L EA+ RK++
Sbjct: 4710 KSLD----KNLKMMKLQKQVIEEEKNKLEQMKIELEK-----EADEIRKIKEETQNERQR 4760
Query: 1034 LHKE----KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE 1201
L K K +KES + + K E+++L+ M+ +L +LQ+ E
Sbjct: 4761 LEKMTEELKKEKESFTHLAEDTKTEKKILDK----MKVANESLMADLQK----------E 4806
Query: 1202 RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDK 1381
+ LE +++ + K+ D +E EK+ ++ R ELE+
Sbjct: 4807 KSNLEEMRENISKQTED------------------SEKEKEKIRLREDELEQ-------- 4840
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKES------KEKQDLEKRVLELTSKLE 1513
L +I+ E+ E N ES K+ +DL+ ++ L LE
Sbjct: 4841 ---LQAEIHKQQGEIK--MEKSNNESERAAIIKDVKDLQHKMFSLDRDLE 4885
Score = 73.6 bits (179), Expect = 3e-10
Identities = 109/526 (20%), Positives = 232/526 (44%), Gaps = 23/526 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N+ D E + + DE N + K+ + +DR+ LE + DLE KT + +
Sbjct: 2795 LQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKER-------FDLEKTKTEMGN- 2846
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
+KK L+ +I + + +E + I+ L
Sbjct: 2847 -----------LKKQLESQIRQHEIQLVEIQKERE--------------------ILEQL 2875
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKSRSLKEHFLREEED 544
++N+ E+L+KE+D D+ +E K ++ E + + ++ +++E D
Sbjct: 2876 KINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTR--------IKQEMD 2927
Query: 545 EVLERSASNLA-------IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 703
E LE++ NLA + K I E+E K + K+ L + E + E Q E+ LE
Sbjct: 2928 E-LEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQN-ERQNLEEA 2985
Query: 704 ASNL----DTMDAIHEEELRKEKVDKSALTE---NGEGCEAEKQGPEKTVLDLEPTIPSL 862
+ L + ++++ EE RK+ V ++ E + E+ KQ E+ +++L+ T+ +
Sbjct: 2986 GTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTVTDI 3045
Query: 863 NDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHK 1042
A + ++++ E++ + + ++++A+ L ++G E++++ N T L +
Sbjct: 3046 AGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGIS---EQQVDIVNKTEQLRLRE 3102
Query: 1043 EKDD--KESIMNDLDHVKAERQVL---ESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
+ + + I D ++A R+ + + ++ +T L E+ Q M+ +D
Sbjct: 3103 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMME-----YASKD 3157
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAK 1387
+ LEK ++ A H ++++ K+ E Q L E+++ + L + K
Sbjct: 3158 -----RANLEKEKSEMIAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMK 3212
Query: 1388 KLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
+L E +LQ+ +L +E+ + + L+++ LEK
Sbjct: 3213 ELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEK 3258
Score = 73.6 bits (179), Expect = 3e-10
Identities = 118/636 (18%), Positives = 269/636 (42%), Gaps = 68/636 (10%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ K ++ + +ND + K+++K + D+ +E K+ +E + D + + +L+++
Sbjct: 3530 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3589
Query: 188 LERKK-------DDNNAI--IKKALDKRISDLKADAPQRDQE--------DDMNALIXXX 316
L+ K ++ N + +K L++ +++ + E +++
Sbjct: 3590 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3649
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLE 496
I+ ++V L ELQKEK + + +++ + E + E
Sbjct: 3650 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3709
Query: 497 SKSRSLKEHFLREEEDEVLERS------ASNLAIMKAIREEELRKEKDGKSALVENGEGC 658
+ L+ +++ + E+S A+ + I++ ++ + + ++D +S ++ E
Sbjct: 3710 DELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRDAESLKLDR-EAF 3768
Query: 659 EAEKQGLE--KTVLERRASNL-------------------------DTMDAIHEEELRKE 757
E E++ L+ KT LER + D ++ + EE RK+
Sbjct: 3769 ENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINNLIEETNRKD 3828
Query: 758 KV--DKS--------ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 907
V +K+ ++ + + E EK EKT +L + + L++ + +AE
Sbjct: 3829 MVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELY----KVKEDLEKQKENTLAE- 3883
Query: 908 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-----KESIMN 1072
++K DLE N ++T +E + H +E K+K D K I N
Sbjct: 3884 --IQKEREDLEKMNENIT-------------IEMHEIKHQEEQMKQKQDELDQLKTEIQN 3928
Query: 1073 DLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 1252
++ E++++ S+++ S L+ + D E NER L+ K+ +E++ +
Sbjct: 3929 LQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQE 3988
Query: 1253 LEATIHDIEMK-TGKDDDYN--EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 1423
+E +++ D+D + +KQ +++ ++LE+ L +A ++ K +E
Sbjct: 3989 MEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNE 4048
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPF 1603
L++ KE++DL + E T + ++ + D + ++ M+D +
Sbjct: 4049 RQSLEKMTKALIKEREDL-VHLAEYTKREKEML----DEMQVANKSSMADLQREKRIL-- 4101
Query: 1604 EDLVQGFSRKTSPLDITKTCDAVDISEDSTTNIQVD 1711
E++ + S++T DI + + ED +Q +
Sbjct: 4102 EEMRENISKQTE--DIENEKEKSKLREDELKKLQTE 4135
Score = 72.8 bits (177), Expect = 6e-10
Identities = 117/569 (20%), Positives = 233/569 (40%), Gaps = 66/569 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAK 169
Q+ + + + + T+ L DE +++ + N+ ++ K +LE ADL+
Sbjct: 13703 QSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRKA 13762
Query: 170 TTLNDELERKKDDNNAIIKKAL--------DKRISDLKADAPQRDQ--EDDMNALIXXXX 319
L++E+ + + I + A ++ + ++AD ++ + E D+ L
Sbjct: 13763 EKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKE 13822
Query: 320 XXXXXXXXXXXIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 487
+ +LE N L L +EL+KEK +I D+ + + V+
Sbjct: 13823 ILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------DAVA 13874
Query: 488 HLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 13875 SLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR 13933
Query: 662 AEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTENGE 793
+ + ++ + E R D + DA+ + +EL K D E+ E
Sbjct: 13934 NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVE 13993
Query: 794 GCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA------- 943
E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 13994 KEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKT 14053
Query: 944 -----KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH--- 1084
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 14054 LVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEV 14113
Query: 1085 ------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGLEKR 1243
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +E
Sbjct: 14114 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE-- 14171
Query: 1244 VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 1423
+EKQ++++ +EL K+L +++ + E
Sbjct: 14172 -----------------------SEKQSIERERAEL-----------KRLKEEVEVQ-HE 14196
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKL 1510
T LQ+D N KEK+ LE T ++
Sbjct: 14197 RTLLQQDKNMIQKEKEHLEGEKARTTEEI 14225
Score = 71.6 bits (174), Expect = 1e-09
Identities = 107/531 (20%), Positives = 221/531 (41%), Gaps = 28/531 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
++ ++ + E T + EL N + K+ I ++R+ +E K L+ + D E + + ++
Sbjct: 2528 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2587
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++++ +IK +K+ + D + +
Sbjct: 2588 ---RRNNEEMVIKLQNEKKDIETSTDR-----------------------------IRDE 2615
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEED 544
E N+ +L + L+ ++D L K+ + + ++ LES++R + ++E
Sbjct: 2616 EANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKER 2672
Query: 545 EVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
E+LE+ L+ K E+E KEK S E E ++E++G+ KT R
Sbjct: 2673 EILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIK 2726
Query: 716 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 895
MD EL++ +++ EN E +KQ ++ + D++
Sbjct: 2727 KEMD-----ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKI 2760
Query: 896 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDK 1057
K L+K D E + + ++ +E + ++ +E S DE + K
Sbjct: 2761 EQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQK 2820
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
+ + +D D ++ ER LE ++M L ++++Q ER+ LE +K L
Sbjct: 2821 QRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLS 2880
Query: 1238 KRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL---- 1372
K+ DLE E + +D ++E++ +K+ + ELE+ L
Sbjct: 2881 KQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQ 2940
Query: 1373 --TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 2941 ENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 2991
Score = 71.6 bits (174), Expect = 1e-09
Identities = 111/536 (20%), Positives = 234/536 (43%), Gaps = 60/536 (11%)
Frame = +2
Query: 86 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERK-KDDNNAIIKKALDKRISD 253
K + NDRN++E + LE ++L + + DE L++K K+ N K +K I +
Sbjct: 10204 KKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVE 10263
Query: 254 LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKE----KDDK 421
+ A +Q +D +++ E + E+++ K+++
Sbjct: 10264 -RLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNER 10322
Query: 422 TALIKDLVAAEPGKRTVNEIVSHLESKSRSL----------------KEHFLREEEDEV- 550
L + + K+ + I+ + L K+ L +E +E+
Sbjct: 10323 ETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEIN 10382
Query: 551 ------LERSASNLAIMKAIREEELRKEK---DGKSALVE-NGEGCEAE-KQGLEKTVLE 697
+R A ++ +EE+L +K + + L E NG+ E + K LE +
Sbjct: 10383 HKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEIN 10442
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT-IPSLNDAL 874
++ L T+ +E++ KEK A+T + E E K+ L E T + L
Sbjct: 10443 QKIEELQTL----QEQIMKEKEKAEAMTIKLK-MEREDLDQIKSELVREKTEVDHEQKKL 10497
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
D+ + EK+ LEK S++ + + E +E++ K++ ++L +D + K K+
Sbjct: 10498 NDDIKMIEQEKEDLEKMKSEIMTQKQEM----EKERSELDNKIQQTDLEKHD-IEKSKEI 10552
Query: 1055 KESIMNDLDHVKAERQVLES-------KVSDMETTY----STLNNELQQKMDDNEAFLNE 1201
E +M +++ + E Q+ + K++D + S L NE ++ + NE E
Sbjct: 10553 VEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKE 10612
Query: 1202 RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------DYNEAEKQTLKKR--ISELEE 1357
R+ L+ ++ LEK ++++ E + K+D D E + +K+R + + +E
Sbjct: 10613 RETLKEMEAHLEKEKEEMKSITE--ETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKE 10670
Query: 1358 AISILTDKAKKLLKDINIWLSEVTE----LQEDLNKESKEKQDLEKRVLELTSKLE 1513
I+ + ++ + + + +S+ E Q+++ +E K ++ + R++E+ +K E
Sbjct: 10671 DINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAE 10726
Score = 71.6 bits (174), Expect = 1e-09
Identities = 109/563 (19%), Positives = 243/563 (43%), Gaps = 50/563 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LER 196
D E+ L++E +D+ K + +N+L +K + +LE T + E +E+
Sbjct: 13935 DLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEK 13994
Query: 197 KKDD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXX 346
++++ N IIK ++L+ I K + A +R Q + + L
Sbjct: 13995 EREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTL 14054
Query: 347 XXIVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
+ + + L LQK+K++ L ++ + AE K V L+ + +
Sbjct: 14055 VQTEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQK 14111
Query: 509 SLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----E 661
+++ + + E +VLE+ S L + + E++++E++ L+E E C E
Sbjct: 14112 EVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE 14171
Query: 662 AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
+EKQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L
Sbjct: 14172 SEKQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNL 14228
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQ 970
+ I + L + A++Q E K+ D+ E TD
Sbjct: 14229 KEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDAS 14288
Query: 971 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL----ESKVSDMETT 1138
+ + + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 14289 QKFQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEM 14347
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
LNNE+++ E+D L+ K ++ ++ + E + + + +++
Sbjct: 14348 RDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE------ 14401
Query: 1319 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 1498
+ L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 14402 -EKLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQL 14460
Query: 1499 TS-KLEKCICGARDGLSTIKEAW 1564
+ E+ I D ST KE +
Sbjct: 14461 KQIEQEREIQRKADVTSTEKEMY 14483
Score = 70.9 bits (172), Expect = 2e-09
Identities = 125/570 (21%), Positives = 246/570 (43%), Gaps = 69/570 (12%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
++++ + I L EL EK+ I+ DR+ L+ + ++L+ +T +ND +
Sbjct: 3916 QDELDQLKTEIQNLQQELEKEKE---IIMKDRS-------ELDLRQSELDKQQTNMNDII 3965
Query: 191 ERKKDDNNAIIKKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVSNL 367
E K++ +K LDK +++ + ++E D+M+ I ++
Sbjct: 3966 ETMKNE-----RKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEE 4020
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS----LKEHFLRE 535
+ + + ELQ+E D+ I+ + +R E ++ K R L E+ RE
Sbjct: 4021 KNKLEQMKFELQREADE----IRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKRE 4076
Query: 536 EE--DEVLERSASNLA-------IMKAIRE------EELRKEKDGKSALVENGEG---CE 661
+E DE+ + S++A I++ +RE E++ EK+ KS L E+ E
Sbjct: 4077 KEMLDEMQVANKSSMADLQREKRILEEMRENISKQTEDIENEKE-KSKLREDELKKLQTE 4135
Query: 662 AEKQ----GLEKTVLERRASNLDTMDAIHEEELRKEKVD-----KSALTENGEGCEAEKQ 814
+KQ +EKT +E + + EL+K+ D K LTE E E +
Sbjct: 4136 VQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEK-ELLENDSN 4194
Query: 815 GPEKTVLDLEPTIPSL---NDALQRDLDRVMAEKQALEKRCSDLE--AKNASLTDNQEGH 979
+K + DL+ + S+ +++L+ D + EK+ L++ +DL+ A + H
Sbjct: 4195 LLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQH 4254
Query: 980 EAEIERKLEASNLTHNDELHK---EKDDKESIMNDLDH--------VKAERQVLESKVSD 1126
+ + + A DE++ E + K+ ++N++D +++++ +LE + +
Sbjct: 4255 DRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHN 4314
Query: 1127 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY 1306
+E T S L + E ER +E +K+ + + + +++ H E K D+
Sbjct: 4315 LEKTRSELARAKENLETQREI---ERKDIEKMKKNISREMHEIK---HQEEQMKQKQDEL 4368
Query: 1307 N-------------EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS--------E 1423
+ E EK+ + K S+L+ S L DK + + DI + +
Sbjct: 4369 DQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSEL-DKQQTNMNDIMETMKNERKQLDKD 4427
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKLE 1513
E +E + KEK D ++ L L+
Sbjct: 4428 KEETEEQKQEMEKEKHDFDQSRKSLDEDLK 4457
Score = 70.9 bits (172), Expect = 2e-09
Identities = 120/625 (19%), Positives = 268/625 (42%), Gaps = 75/625 (12%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNE----KDDKKCIVNDR-NILEAAKQALEYKVADLEAAKT 172
L+ ++ +F+A ++ ++ L + K+D+K + + N++E +A + +++ K
Sbjct: 10957 LQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKA---EPEEIKKEKE 11013
Query: 173 TLNDELERKKDDNNAII---KKALDKRISDLKADAPQRDQE----DDMNALIXXXXXXXX 331
N+E E ++++ I+ +K L + S+L+ + D E +D +I
Sbjct: 11014 KENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKED-- 11071
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
+ ++ I+ +++++E+ + I+ + H KS+
Sbjct: 11072 --------LEKMKSEIMKQRQQMEEERSELDNKIQQ-----------TNLEKHDIEKSKE 11112
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV 691
+ E + E E++ ++ + K + E +K D ++ LV+N + E + ++K V
Sbjct: 11113 IVEKLMVEVEEQ-----RKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKK-V 11166
Query: 692 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
E +T+ + E L+KEK + ++ E + + + + + + + + + D
Sbjct: 11167 DEEIKKERETLREM-EIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDL 11225
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK---------LEASNLTH 1024
L+++ + + E L++R + +A+ + ++ E E ERK +E
Sbjct: 11226 LEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAE 11285
Query: 1025 NDELHKEKDDK-ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE 1201
E+ +EK+++ E M + V+ ER+ L S+++ S +++E ++ DD + E
Sbjct: 11286 LQEIMQEKEEEDEEEMRVI--VEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQE 11343
Query: 1202 RDGLEAVK-------QGLEKRVLDLEATI-------HDIE-------------------M 1282
++ LE +K Q +E+ +L+ I HDIE +
Sbjct: 11344 KEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDI 11403
Query: 1283 KTGKDD---------------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 1417
+ K++ N+A+ Q +RI E++E I K K+ LK++ L
Sbjct: 11404 RLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHL 11459
Query: 1418 SEVTELQEDLNKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 1591
+ E + +E+ ++K+DLEK ++ +K + + RD L +E +
Sbjct: 11460 RKEKEEMRSVIEETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHK 11512
Query: 1592 WVPFEDLVQGFSRKTSPL---DITK 1657
W + + F + S D+TK
Sbjct: 11513 WTQLQQRIDEFDAQVSKQKEEDLTK 11537
Score = 69.3 bits (168), Expect = 7e-09
Identities = 116/533 (21%), Positives = 226/533 (42%), Gaps = 17/533 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ +E KQ +E + +++ ++ +L+++
Sbjct: 5487 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 5546
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++ K + K+ ++ + L+ + ++E D + I N
Sbjct: 5547 QKKMK-----LQKQMFEEEKNKLEQMKIELEREADEISKIKEE-------------TQNK 5588
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
+ + EEL +EK+ L +D + K+ ++E+ ES L + E
Sbjct: 5589 RQRLEKMTEELIREKESLAHLAED---TKTEKKILDEMKVANESSMADL------QREKS 5639
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSAL--VENGEGCEAEKQGLEKTVLERRASNLDT 721
+LE N++ +K + E K K + L ++ + K +EKT +E + +
Sbjct: 5640 ILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIR 5699
Query: 722 MDAIHEEELRKEKVD-----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
EL+K+ D K LTE E + D+E L D L+RD
Sbjct: 5700 EKQNMMTELKKKSEDVEIQMKEILTEK----ELLHNDRKLLTRDVENLQQKLID-LERDS 5754
Query: 887 DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDE-----LHKEK 1048
R+ +++A E ++ EA TD Q + EIE+ KLE + E + KE+
Sbjct: 5755 KRLKLDREAFE---NEKEAMKQMKTDLQIQAD-EIEKIKLETQHDRQRVEEMAAQIQKER 5810
Query: 1049 DDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 1228
D I N ++ + VL K D+E ++ ++ + R L VK+
Sbjct: 5811 D---KINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKE 5867
Query: 1229 GLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDIN 1408
LEK+ E T+ +I+ + + NE + + + I EE ++ D+ +L
Sbjct: 5868 DLEKQ---KENTLAEIQKEREDVEKMNENITREMHE-IKHQEEQMNQKQDELDQL----- 5918
Query: 1409 IWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEKCICGARDGLSTIK 1555
+E+ LQ++L KE K++ + R S+L+K D + T+K
Sbjct: 5919 --KTEIQNLQQELEKEKEIIMKDRSQFDLR----QSELDKQQTNMNDIMETMK 5965
Score = 68.9 bits (167), Expect = 9e-09
Identities = 117/544 (21%), Positives = 231/544 (42%), Gaps = 39/544 (7%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDD--------KKCIVNDRNILEAAKQALEYKVADL 157
Q AD E + EL KD+ +K V+ + + +++ E +L
Sbjct: 1460 QTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIEL 1519
Query: 158 EAAKTTLN---DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 328
E A+ LN ++E +K A +K L K +L+A ++ ED+ AL
Sbjct: 1520 EKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ--RKMMEDEKRALENMKYELQ 1577
Query: 329 XXXXXXXXIVSNLEVNILILH----------EELQKEKDDKTAL-------IKDLVAAEP 457
N+ + EEL+K++ D L IKDL
Sbjct: 1578 RESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDL----E 1633
Query: 458 GKRTVNEI-VSHLESKSRSLKE-HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 631
R +NE+ ++ +++KS L++ L ++ + +E S + I RE +L++ + +
Sbjct: 1634 NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKI----REYDLQQMQTDLN 1689
Query: 632 ALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG-EGCEAE 808
+ E Q ++ V ++ + D I E+ K+ D T+N + + E
Sbjct: 1690 RQ-------QKEMQDIQNAVFMEKSELKKSQDEIAEQ--LKQVGDMMQFTQNEKDNLDRE 1740
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRV-MAEKQALEKRCSDLEAKNASLTDNQEGHEA 985
+ + L +E + L L R+L+ + + +K+ L ++ + + + + D Q+ +
Sbjct: 1741 RAAIIEQKLQMERDMTHL---LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQM 1797
Query: 986 EI--ERKLEASNLTHNDELHKEKDDKESIMNDL--DHVKAERQVLESKVSDMETTYSTLN 1153
+I ER+ E L + +EKD ES++ L D K L K +E L
Sbjct: 1798 KINLEREKEEMQL-QRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK-QKLEDAAVELQ 1855
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 1333
E + M+ E +R+ ++ ++ G+EK+ E T D++ K+ E ++Q ++
Sbjct: 1856 KERDEIMNIAEETKRKREDVDKIRVGIEKQ----EITFKDLKADLQKEAAIVENQRQAVQ 1911
Query: 1334 K---RISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
K + ++E I +L+++I + E+Q +++KE +E + + + TS
Sbjct: 1912 KDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETS 1971
Query: 1505 KLEK 1516
KL +
Sbjct: 1972 KLRE 1975
Score = 68.9 bits (167), Expect = 9e-09
Identities = 104/526 (19%), Positives = 213/526 (40%), Gaps = 32/526 (6%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKC----IVNDRNILEAAKQALEYKVADL------ 157
L+ V D L ++LL E++ K I ++++L KQ + + D+
Sbjct: 3038 LKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQ 3097
Query: 158 ----EAAKTTLNDELERKKDDNNAIIKKALDK--RISDLKADAPQRDQEDDMNALIXXXX 319
E L + R++D+ A K +++ R+ K + + +E +
Sbjct: 3098 LRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKD 3157
Query: 320 XXXXXXXXXXXIVSNLEVNILILHEELQKEK---DDKTALIKDLVAAEPGKRTVNEIVSH 490
I +++I EL KE+ +++T ++ KRT E+
Sbjct: 3158 RANLEKEKSEMIAQKHQMDI-----ELNKERGLIEERTQMLNTYEKEMDQKRTALEV--- 3209
Query: 491 LESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E K + ++EE++++ L+R A ++ +K E+ R E+ + EN
Sbjct: 3210 -EMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLK----EKTRNERQSLEKMAEN-- 3262
Query: 653 GCEAEKQGLEKTVLERRASNLDTMDAIHEE---ELRKEKVDKSALTEN----GEGCEAEK 811
E EK L + + + D M +HE +++KEK + + E+ E ++EK
Sbjct: 3263 -LEKEKDDLAHLAEDTKRKD-DEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEK 3320
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
K ++ E + + + R + +K +E + + KN L
Sbjct: 3321 ----KKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMT--------- 3367
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQK 1171
EL K+ +D E M + V E+++LES ++ L +L
Sbjct: 3368 -------------ELTKQSEDVEIQMKE---VLTEKELLESDRKLLKKDVENLQQKLLII 3411
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 1351
D+E+ +R+ LE K+ L++ DL+ +IE K + + + + +I +
Sbjct: 3412 ESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE-KIKLETQHERQRVEEMTAQIQKD 3470
Query: 1352 EEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
E + + D + + DI ++ + Q++L++ E Q+L++ +
Sbjct: 3471 REYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQEL 3516
Score = 68.6 bits (166), Expect = 1e-08
Identities = 121/564 (21%), Positives = 227/564 (40%), Gaps = 64/564 (11%)
Frame = +2
Query: 17 KVADFEATIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 193
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 13089 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 13146
Query: 194 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 13147 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 13188
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 13189 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 13248
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 721
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 13249 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 13304
Query: 722 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 874
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 13305 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 13362
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKLEA 1009
+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 13363 EESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRERE 13422
Query: 1010 SNLTHNDELHKEKDD----KESIMNDLDHV----------KAERQVLESKVSDMETTYST 1147
D+L KEK+D KE I + +H+ K E + K+ M+T
Sbjct: 13423 EIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQV 13482
Query: 1148 LNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATIHD 1273
N L++ M D + ER+ + A+ K+ ++ +L +++ D
Sbjct: 13483 KTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 13539
Query: 1274 IE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 1444
IE +K + N+ +K LK R ELE I KK K+ ++ E+Q +
Sbjct: 13540 IESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQRE 13589
Query: 1445 LNKESKEKQDLEKRVLELTSKLEK 1516
K +LE++ EL +K+EK
Sbjct: 13590 RKALEKMNAELERKSTELKNKIEK 13613
Score = 65.9 bits (159), Expect = 7e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = +2
Query: 461 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 637
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 638 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 817
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 818 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 998 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 1126
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 1127 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 1303
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 1304 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 1462
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 1463 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 1627
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 1628 RKTSPLDITKT-----CDAVDISEDST 1693
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 1e-07
Identities = 118/608 (19%), Positives = 236/608 (38%), Gaps = 108/608 (17%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKT 172
++ D E + LN+ LN+ K ++ ++ +E K ++ + DL+ +T
Sbjct: 1628 EIKDLE-NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1686
Query: 173 TLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 346
LN + + +D NA+ K L K ++ A Q Q DM
Sbjct: 1687 DLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK--------- 1734
Query: 347 XXIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
NL+ I+ ++LQ E+D L ++L + + K+ V LE SL
Sbjct: 1735 ----DNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRD 1790
Query: 524 FLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKT 688
E+ ++ LER + + + EE K + L E+ E AEKQ LE
Sbjct: 1791 MQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDA 1850
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDK----------------------SALTENGEGC- 799
+E + + M+ E + ++E VDK +A+ EN
Sbjct: 1851 AVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAV 1910
Query: 800 --------------EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 937
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +L
Sbjct: 1911 QKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDEL 1966
Query: 938 EAKNASLTDNQEGHEAEIER----KLEASNLTHNDELHKEKDDKESIMNDLD-------- 1081
E + + L ++++ + E+ + E + N EL E KE + +L+
Sbjct: 1967 EQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRE 2026
Query: 1082 -------------------------HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
++A++ K ++T L+++ + E
Sbjct: 2027 NEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEME 2086
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKK 1336
+ E + +E K+ + ++ E+ + +EM+ Y E ++Q +K
Sbjct: 2087 SLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEK 2146
Query: 1337 RISELEEAISILTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVL 1492
I ++ + I + ++ K++ I V E Q+ + ++SK E ++ K++
Sbjct: 2147 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKIN 2206
Query: 1493 ELTSKLEK 1516
S++EK
Sbjct: 2207 ADLSEVEK 2214
Score = 63.9 bits (154), Expect = 3e-07
Identities = 103/563 (18%), Positives = 240/563 (42%), Gaps = 74/563 (13%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 226
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 11093 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 11152
Query: 227 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIV 358
K +D+ I + + + +++++ ++I +
Sbjct: 11153 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 11212
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 538
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 11213 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 11265
Query: 539 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 700
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 11266 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 11321
Query: 701 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 838
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 11322 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 11376
Query: 839 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1015
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 11377 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 11435
Query: 1016 LTHNDELHKEKDDKESIMNDLDHVKAERQVLES--------KVSDMETTYSTLNNELQQK 1171
+ + K +KE++ H++ E++ + S K D+E + +N + Q
Sbjct: 11436 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 11495
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 1330
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 11496 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 11555
Query: 1331 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 1459
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 11556 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11615
Query: 1460 K----EKQDLEKRVLELTSKLEK 1516
K EK+DLEK E+ + ++
Sbjct: 11616 KMIEQEKEDLEKMKSEIMKQRQQ 11638
Score = 63.9 bits (154), Expect = 3e-07
Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 16/514 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALE-YKVADLEAA------ 166
+EN F IA L ++ K DK+ I N+ L+ +Q E + AD+ +
Sbjct: 14425 IENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKADVTSTEKEMYT 14484
Query: 167 -KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXX 343
K T ELE K+ IK D + D+ + D E + L
Sbjct: 14485 EKVTYKTELEDSKEK----IKPDRDSTLELTDTDSAKTDGEREAQTL-----------ET 14529
Query: 344 XXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
V L + EEL E ++K +I +L A+ + + L+ + RS +E
Sbjct: 14530 KVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAK-------KDLQKLKEECRSAEEE 14582
Query: 524 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLER 700
+ E LER ++L E+++ E + +++ + E Q +E K ++
Sbjct: 14583 --KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQT 14632
Query: 701 RASNLDTMDAIHEEELRKEKVDKSA-LTENGEGCEAEKQGPEKTVLDLEPTIPS-LNDAL 874
R+ + ++ +E ++ + +T+ E + K+ + V LE T+ S + +
Sbjct: 14633 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMR 14692
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
+++ V K ++ LE + + E E +E L+ + + + L + D
Sbjct: 14693 DMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKS-RNEETLLQLLHD 14751
Query: 1055 KESIMNDLDHVKAERQ----VLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAV 1222
K+ + N LD E + + ++ +ETT + + +
Sbjct: 14752 KDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKD--------------------- 14790
Query: 1223 KQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLK 1399
K+ +E +L L+ T + E++ G DD NE E K +ELE+ + + KK +
Sbjct: 14791 KENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELED-----SKEKKKPDR 14845
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
D ++ L++ + D +E++ + + VL+LT
Sbjct: 14846 DSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 14879
Score = 63.5 bits (153), Expect = 4e-07
Identities = 113/537 (21%), Positives = 220/537 (40%), Gaps = 46/537 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL--------- 178
+ E T NDE+ EK I + + +L + LE ADLE K +
Sbjct: 8155 NMEKTYEQQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLA 8211
Query: 179 -NDELERKKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXX 334
N+ LER+K D II+ +A +R ++ A A +RD E+ M +
Sbjct: 8212 ENELLEREKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQE 8270
Query: 335 XXXXXXI--------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH 490
+ + L+ ++L EL+K K D + DL ++T +EI+ H
Sbjct: 8271 ASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKH 8324
Query: 491 ---LESKSRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENG 649
+SK+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 8325 EKDTDSKTRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM---- 8379
Query: 650 EGCEAEKQGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEK 811
K V+ +R D M+ I EE+ +E+ + L N + +
Sbjct: 8380 -----------KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDF 8424
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ + +LE ++ D++R++ E + + +L+ E+
Sbjct: 8425 ELLLERTANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EM 8465
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTL 1150
ER++E S + DE K + + + D+ ++ L ++ ++E + L
Sbjct: 8466 ERRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAEL 8524
Query: 1151 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL 1330
+ Q++ E ER+ LE +K + + D+E +E K++ + Q
Sbjct: 8525 AEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKY 8584
Query: 1331 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 1498
K+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8585 KEELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8637
Score = 63.5 bits (153), Expect = 4e-07
Identities = 118/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = +2
Query: 2 QALENKVAD-FEATIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 172
Q LE KV D + T T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 14866 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 14925
Query: 173 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 274
+ + LER+++ + + L ++ +K + Q
Sbjct: 14926 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 14985
Query: 275 ----RDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDL 442
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 14986 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 15042
Query: 443 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 619
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 15043 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 15102
Query: 620 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 733
D K+ +EN E E E L++T ER T D
Sbjct: 15103 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 15161
Query: 734 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 910
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 15162 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 15209
Query: 911 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVK 1090
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 15210 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 15250
Query: 1091 AERQVLESKVSDMETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 1249
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 15251 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 15310
Query: 1250 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 1420
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 15311 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 15370
Query: 1421 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 1513
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 15371 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 15412
Score = 63.2 bits (152), Expect = 5e-07
Identities = 92/503 (18%), Positives = 207/503 (41%), Gaps = 36/503 (7%)
Frame = +2
Query: 56 DELLNE-KDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKA 232
D+L E ++DK ++ N +A ++ L + LE + + E+ K++ + I
Sbjct: 753 DKLKGEMEEDKHVVIMQMNEAKAKEEQLTMVIEQLEIERGEITISREKVKEELDEI---- 808
Query: 233 LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEK 412
++ ++L+ Q +M V E+ + EE +K +
Sbjct: 809 -NRMRNELQR------QHAEMEDWFRVVNKEKEEANLAKLAVHEAEMLLKKQMEESEKRR 861
Query: 413 DDK-TALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE--HFLREEEDEVLERSASNLAIM 583
+ T ++ + + +I ++ + L++ +F +E ++LE + +
Sbjct: 862 YEMITEALEQRDEIQKKAEELEQINKEIQRARQELEKMRYFEKESLQKMLEDTQQERVFV 921
Query: 584 KAIREEELRKEKDGKSALVE-NGEGCEAEKQGL----EKTVLERRASNLDTMDAIHEEEL 748
+ +R E L+ + D L E + E E E+ EK LE+R + D ++
Sbjct: 922 EQVRSELLKNKADQDKCLFEMDSERKELEQMRFQVENEKKDLEQRRYEMMRYDVEQSAQV 981
Query: 749 RKEK-----------VDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 895
+++K +D ++ + E +++ E +++++ +N L+ R
Sbjct: 982 QRQKEELEKIKSQLVIDTESMNRSRELARQDREKAELLIVEIQEQREDVNKRLEETKQRE 1041
Query: 896 MA----------EKQALEK-RCSDLEAKNASLTDNQEGHE--AEIERKLEASNLTHNDEL 1036
A E++ LEK R L K+ +E + AEIER + + +E
Sbjct: 1042 EALRLLRKDMENEREDLEKIRVETLRGKDTYEEVKEEINRVRAEIERLWDEAEKGDQEER 1101
Query: 1037 HKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 1216
K +KE ++ ++ +K E ++ DM+ + + KM+ E LE
Sbjct: 1102 EKINHEKEEMIRKMEAMKREM----GEIEDMKVELTKQKENIDMKMEHARL---EMTNLE 1154
Query: 1217 AVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISIL---TDKAK 1387
+K L ++ D+E + + + E + + K+ +LEE + + D+ +
Sbjct: 1155 MMKADLLRQKEDIENQM----LAAKSERQQMEVMRTEILKQKEDLEERLEEVIKENDRVE 1210
Query: 1388 KLLKDINIWLSEVTELQEDLNKE 1456
++ +D+N L ++ + +ED+ ++
Sbjct: 1211 QMREDVNNALKDIDQAKEDIQRQ 1233
Score = 61.2 bits (147), Expect = 2e-06
Identities = 118/559 (21%), Positives = 227/559 (40%), Gaps = 54/559 (9%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--------- 160
LE A E L+ EL K+ I ++R LE K L+ K D+E
Sbjct: 7756 LEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYE 7815
Query: 161 ----AAKTTLNDELERKKDDNNAIIKKA------LDKRISDLKADAPQRDQEDD---MNA 301
A + + N +++ D+ NA ++K D+ + K + + E + A
Sbjct: 7816 KQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKARAETERVKQGA 7875
Query: 302 LIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIK--DLVAAEPGKRTVN 475
I + ++ N+ E ++K+K + + DL+ A+ K+
Sbjct: 7876 KIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEE 7935
Query: 476 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG 655
+ +ES+ +E + +E LE + + I + L+ E DGK V+N
Sbjct: 7936 MVKQKIESEREIQQEKKKLQRSEEELEDKMQKIK-REMIELKLLQDETDGKRKDVDN--- 7991
Query: 656 CEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL 835
+ + R+ L+ M A E +K +VD+ L + E K ++
Sbjct: 7992 --------KMRQVARKRDELEKMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE 8043
Query: 836 DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL--EAKNASLTDNQEGHEAEIERKLEA 1009
++ + A +R D + EK+ + R L EA+ AS HE E+ + E
Sbjct: 8044 HMQ------SHAEERAGD--LGEKEPVNTRIQRLIQEAEKASKMAWSTKHEPEMRMQREV 8095
Query: 1010 S----NLTHND----------ELHKEKDDKESIMNDLDHVKAERQVLE-------SKVSD 1126
S ++ D E+ ++ + +++ + ER LE + +
Sbjct: 8096 SVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKN 8155
Query: 1127 METTYSTLNNELQ---QKMDDNEAFLN-ERDGLEAVKQGLE--KRVLDLEATIHDIEMKT 1288
ME TY N+E+Q Q+++ ++ L+ ER+ LE + LE K+++ L+ + K
Sbjct: 8156 MEKTYEQQNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALD------KQKL 8209
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILT-DKAKKLLKDINIWLSEVTELQEDLNKESKE 1465
+++ E EK + K I LE T ++A + + E+ + E L+ E +
Sbjct: 8210 LAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQ 8269
Query: 1466 KQDLEKRVLELTSKLEKCI 1522
+ + +++EL +++K I
Sbjct: 8270 EAS-KNQMVELKRQIDKLI 8287
Score = 60.8 bits (146), Expect = 2e-06
Identities = 117/551 (21%), Positives = 209/551 (37%), Gaps = 81/551 (14%)
Frame = +2
Query: 56 DELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK---TTLNDELERKKDD--NN 214
++LL E +K+ ND + E K+ ALE + D+ K +L +E+ K+ + N
Sbjct: 13831 NDLLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNK 13890
Query: 215 AIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
K + DL+ R Q+ +++ I ++LE
Sbjct: 13891 ETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR----------NDLESMK 13940
Query: 380 LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK---EHFLREEEDEV 550
+L EE ++ +D+ P K + LE + +K EH +E E
Sbjct: 13941 TLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKERE--- 13997
Query: 551 LERSASNLAIMKAIRE--------EELRKEKDGKSALVENGEGCEAE----KQGLEKTVL 694
E N I+K+ E E ++E GK A +E+ E A+ ++ V
Sbjct: 13998 -EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 14056
Query: 695 ERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
+ ++ + E EL+ + K+ L E EAEK E + L+ + D
Sbjct: 14057 TEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDI 14116
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL---------------- 1003
+ + +E+ LEK S+L + L + + + E+ER L
Sbjct: 14117 MTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIES 14172
Query: 1004 ----------EASNLTHNDELHKEK----DDKESIMNDLDHVKAER-------QVLESKV 1120
E L E+ E+ DK I + +H++ E+ L+ ++
Sbjct: 14173 EKQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEI 14232
Query: 1121 SDMETTYSTLNNELQQKMDDNEAF-----LNERDGLEAVKQGLEKRVL-----------D 1252
+ LN E++ K + E + D L+ L + ++
Sbjct: 14233 KRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQ 14292
Query: 1253 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 1432
L+ T D E +T D+ +T ++R LEE ++ T K ++K + SEV E
Sbjct: 14293 LKTTSRDAETQTSLDE-----ITKTDERRQRALEETVA-TTAKQPIVIKLEDTLTSEVQE 14346
Query: 1433 LQEDLNKESKE 1465
+++ LN E KE
Sbjct: 14347 MRDHLNNEIKE 14357
Score = 60.5 bits (145), Expect = 3e-06
Identities = 112/543 (20%), Positives = 217/543 (39%), Gaps = 48/543 (8%)
Frame = +2
Query: 14 NKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN-DEL 190
+K+ + +A + EL K D K ++D LE + + D ++ L E+
Sbjct: 8284 DKLIELKADLLQQQTELKKTKADLKQQMDD---LEKTRSEILKHEKDTDSKTRELELIEI 8340
Query: 191 ERKKDDNNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXXIV 358
+R+KDD I+K L+KR + L+++ ++D + M +I
Sbjct: 8341 QRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANAT 8400
Query: 359 SNLE---VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSR 508
+ + IL +Q + D +TA ++D +A +R V E+V + R
Sbjct: 8401 EEINRERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVR 8459
Query: 509 SLK---EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQG 676
+LK E + + + E+ E+ I + I++ ++R+ G +E + E +
Sbjct: 8460 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 8519
Query: 677 LEKTVLERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT 829
+ + E++ + +H+E E+ +EK D E E +++ E T
Sbjct: 8520 MRAELAEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFT 8579
Query: 830 -VLDLEPTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
+ + + S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +
Sbjct: 8580 DIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-K 8638
Query: 998 KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 1177
K E DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8639 KGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDL 8698
Query: 1178 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------ 1339
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8699 FRSELQRQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKI 8755
Query: 1340 ----------ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
I + + IL D + +D + E +L E D+E+ V
Sbjct: 8756 RFDIANARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLV 8811
Query: 1490 LEL 1498
LE+
Sbjct: 8812 LEV 8814
>ref|XP_685984.6| PREDICTED: titin isoform X7 [Danio rerio]
Length = 15997
Score = 101 bits (251), Expect = 2e-18
Identities = 132/600 (22%), Positives = 266/600 (44%), Gaps = 39/600 (6%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRN--------ILEAAKQALEYKVADL 157
Q +E A + +N+ L+ E + K ++N++N +++ K LE + DL
Sbjct: 6465 QRVEEMTAQIQKDRDKINN-LIEETNRKDMVLNEKNRDIEKKIKSIQSDKDMLEKEKHDL 6523
Query: 158 EAAKTTL---NDELERKKDDNNAIIKKA---LDKRISDLKADAPQ-RDQEDDMNALIXXX 316
E ++ L ++LE++K++ A I+K L+K ++ + + + QE+ MN
Sbjct: 6524 EKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMHEIKHQEEQMNQ----- 6578
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKRTVNEIV 484
+ L+ I L +EL+KEK+ ++ L + + + +N+I+
Sbjct: 6579 ---------KQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMNDIM 6629
Query: 485 SHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
++++ + L K+ EE+ + +E+ N+ + +E+L+ K K + E E
Sbjct: 6630 ETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDLKMMKLQKQVIEEEKNKLE 6689
Query: 662 AEKQGLEKTVLERRASNLDTMDAIH-----EEELRKEKVDKSALTENGEGCEAEKQGPEK 826
K LE+ + R +T + EEL+KE+ D + L E+ + EK ++
Sbjct: 6690 QMKIELEREADDIRKIKEETQNKRQILEKMAEELKKERKDVAHLAED---TKREKNSLDE 6746
Query: 827 TVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLE 1006
+ E ++ L Q++ + K+ + K+ D+E + D E E+E+ L+
Sbjct: 6747 MKVANESSMADL----QKEKSNLEEMKENISKQTEDIEKEK----DKIRLREDELEQ-LQ 6797
Query: 1007 ASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
A E+HK++ + E + +++ ER + V D+++ +L+ + + D E
Sbjct: 6798 A-------EIHKQQSETEI---EKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDRE 6847
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLE----ATIHD----IEMKTGKDDDYNEAEKQTLKKRI 1342
AF NE++ L+ +K LE+ ++E T H+ EM + N KQ K ++
Sbjct: 6848 AFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKV 6907
Query: 1343 ------SELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
E+E+ + K L +D+ + ++ L+E+ NK + K LE+ E+ S
Sbjct: 6908 MIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEI-S 6966
Query: 1505 KLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGFSRKTSPLDITKTCDAVDISE 1684
K+++ R L + A + E L + RK LD K + +++
Sbjct: 6967 KIKEETQNERQNLEKMANALKEE---------REYLAEEIKRKNQVLDKIKVANESTLAD 7017
Score = 99.8 bits (247), Expect = 5e-18
Identities = 131/591 (22%), Positives = 260/591 (43%), Gaps = 87/591 (14%)
Frame = +2
Query: 5 ALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTT--- 175
A+ V D + + +L+ +L + K D++ N+R +L+ K L+ K ++E K
Sbjct: 5116 AIIKDVKDLQHKMFSLDRDLESLKLDREAFENEREVLKQIKTDLKRKAEEIEKIKLETQH 5175
Query: 176 -------LNDELERKKDDNNAIIKKA--LDKRISDLKADAPQRDQ--EDDMNALIXXXXX 322
+ ++++++D N +I++ D ++++K + ++ + E D + L
Sbjct: 5176 DRQRVEEMTAQIQKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHD 5235
Query: 323 XXXXXXXXXXIVSNLEVNILILHEELQKEKDDK-------TALIKDLVAAEPGKRTVNEI 481
NLE I E+QKE++D T I D+ E + +
Sbjct: 5236 LEKTRSKLLRAKENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDE 5295
Query: 482 VSHLESKSRSLKEHFLREEEDEVLERSASNLA-------------IMKAIREEELRKEKD 622
+ L+++ ++L++ +E+E + +RS +L IM+ ++ E + +KD
Sbjct: 5296 LDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKD 5355
Query: 623 GKSALVENGEGCEAEKQG----------------LEKTVLERRASNLDTMDAIHEEELRK 754
K E + E EK L+K VLE S L+ M EL +
Sbjct: 5356 -KEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKI----ELER 5410
Query: 755 EKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSD 934
E V+ + E + E+Q EK L+ L + +++ + K A E +D
Sbjct: 5411 EAVEIRKIKEE---IQNERQNLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLAD 5467
Query: 935 LEAKNASLTDNQEG---HEAEIERKLEASNLTHND------ELHKEKDDKESIMNDLDHV 1087
+ + ++L + +E ++E K E L ++ E+HK++ + E + ++
Sbjct: 5468 ILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEIHKQQREIEK---EKINI 5524
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE--- 1258
++ER + V D++ L+ + + D EAF NE++ L+ +K LE+ ++E
Sbjct: 5525 ESERAAIIKDVEDLQHKIICLDRDAESLKLDREAFENEKEVLKQMKTELEREADEIEKIK 5584
Query: 1259 -ATIHD--------IEMKTGKDDDYNEAEK-----QTLKKRISELEEAI-SILTDK--AK 1387
T HD +++ +D+ N E+ L ++ ++EE I SI +DK +
Sbjct: 5585 LETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLE 5644
Query: 1388 KLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLEK 1516
K D+ SE+ +++EDL K+ KE++DLEK +T ++ +
Sbjct: 5645 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHE 5695
Score = 99.4 bits (246), Expect = 6e-18
Identities = 124/547 (22%), Positives = 230/547 (42%), Gaps = 48/547 (8%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNA 217
+ +EL EK+ + D + IL+ K A E +ADL+ K+ L + E
Sbjct: 5015 MTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTED 5074
Query: 218 IIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEE 397
K+ R+ + + + Q + + V +L+ + L +
Sbjct: 5075 SEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNESERAAIIKDVKDLQHKMFSLDRD 5134
Query: 398 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVL-------- 553
L+ K D+ A E + + +I + L+ K+ +++ L + D
Sbjct: 5135 LESLKLDREAF-------ENEREVLKQIKTDLKRKAEEIEKIKLETQHDRQRVEEMTAQI 5187
Query: 554 --ERSASNLAIMKAIREEELRKE-----KDGKSALVENGEGCEAEKQGLEKT--VLERRA 706
ER N I + R++ + E K+ A+ + + E EK LEKT L R
Sbjct: 5188 QKERDKINNLIEETNRKDMVLNEIKTEIKEKIKAIESDRDMLEKEKHDLEKTRSKLLRAK 5247
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTE------NGEGCEAEKQGPEKTVLD-LEPTIPSLN 865
NL+ I E++KE+ D + E + + E+ ++ LD L+ I +L
Sbjct: 5248 ENLEKQRKIKLAEIQKEREDLEKMNEKFTIEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ 5307
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
L+++ + +M ++ L+ R S+L+ + ++ D E + E ++ K + E+
Sbjct: 5308 QELEKEKEIIMKDRSQLDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEME 5367
Query: 1040 KEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
KEK D ++S+ DL +K ++QVLE + S +E L E + E NER
Sbjct: 5368 KEKHDFDQSRKSLDEDLKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQ 5427
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL------KKRISELEEAISI 1369
LE + + L++ DL + + D+ A + TL K + E+ E IS
Sbjct: 5428 NLEKMTEALKEEREDL---AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISK 5484
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKE----SKEKQDLEKRVLELTSKLE----KCIC 1525
T+ + +++ + E+ +LQ +++K+ KEK ++E + +E K IC
Sbjct: 5485 QTEDVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIIC 5544
Query: 1526 GARDGLS 1546
RD S
Sbjct: 5545 LDRDAES 5551
Score = 94.0 bits (232), Expect = 2e-16
Identities = 133/541 (24%), Positives = 243/541 (44%), Gaps = 54/541 (9%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE + LE YKV DLE K E++++
Sbjct: 6075 DMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKEDLEKQKENTLAEIQKE 6134
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 6135 REDVEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 6173
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 6174 QNLQQELEKEKEIIMKDRSQF--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 6231
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 718
+ + +E+ + + +++L+ K K E E K LE+ E R +
Sbjct: 6232 QKQEMEKEKHDFDQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEE 6291
Query: 719 TMDAIHE-----EELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRD 883
T + EEL+KEK + L E+ + E+ +LD + N++L D
Sbjct: 6292 TQNERQSLEKMTEELKKEKESFTHLAEDTK--------KEQEILD---KVKVANESLMAD 6340
Query: 884 LDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKDDK 1057
L + EK LE+ ++ + + + +E + +L+A E+ KEK +
Sbjct: 6341 LQK---EKSNLEEMRENISKQTEDVENKKENLRLREDELWQLQAEIYKQQREIEKEKINI 6397
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
ES ER + V D++ +L+ + + D EAF NER+ L+ +K LE
Sbjct: 6398 ES----------ERAAIIKNVEDLQHKIISLDRDSESLKLDREAFENEREVLKQMKTELE 6447
Query: 1238 KRVLDLE----ATIHD---IEMKTG---KD-DDYNEAEKQT------LKKRISELEEAI- 1363
+ ++E T HD +E T KD D N ++T L ++ ++E+ I
Sbjct: 6448 READEIEKIKLETQHDRQRVEEMTAQIQKDRDKINNLIEETNRKDMVLNEKNRDIEKKIK 6507
Query: 1364 SILTDK--AKKLLKDINIWLSEVTELQEDLNKE--------SKEKQDLEKRVLELTSKLE 1513
SI +DK +K D+ SE+ +++EDL K+ KE++DLEK +T ++
Sbjct: 6508 SIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAQIQKEREDLEKMNENITREMH 6567
Query: 1514 K 1516
+
Sbjct: 6568 E 6568
Score = 92.8 bits (229), Expect = 6e-16
Identities = 122/541 (22%), Positives = 232/541 (42%), Gaps = 42/541 (7%)
Frame = +2
Query: 2 QALENKVADFEATIATLN---------DELLNEKDDK-----KCIVNDRNILEAAKQALE 139
Q +E K A + +N D +LNE D K I +D+++LE + LE
Sbjct: 4508 QRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHNLE 4567
Query: 140 YKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXX 319
++L AK L + E ++ D + KK + + + ++K Q Q+ D
Sbjct: 4568 KTRSELARAKENLETQREIERKDIEKM-KKNISREMHEIKHQEEQMKQKQDE-------- 4618
Query: 320 XXXXXXXXXXXIVSNLEVNILILHEELQKEKDD--KTALIKDLVAAEPGKR--TVNEIVS 487
+ L+ I L +EL+KEK+ K DL +E K+ +N+I+
Sbjct: 4619 ------------LDQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIME 4666
Query: 488 HLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 664
++++ + L K+ EE+ + +E+ + + +E+L+ K K + E E
Sbjct: 4667 TMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEE-----EK 4721
Query: 665 EKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLE 844
K K LER A +E+RK K + T+N E+Q EK L+
Sbjct: 4722 SKLKQMKIELEREA-----------DEIRKVKEE----TQN------ERQIFEKMTEALK 4760
Query: 845 PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEG---HEAEIERKLEASN 1015
L++ +R + K A E +D+ + ++L + +E ++E K E
Sbjct: 4761 KEREDLSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIR 4820
Query: 1016 LTHND------ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 1177
L E+HK++ + E + +++ ER + V D+++ +L+ + +
Sbjct: 4821 LREEKLKQLQAEIHKQQSETEK---EKSNIERERAAIIKDVEDLQSKIISLDRDAESLKL 4877
Query: 1178 DNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIEMKTGKDDDYNEA---------- 1315
D EAF NE++ L+ +K LE+ ++E T H+ + D+ E
Sbjct: 4878 DREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNK 4937
Query: 1316 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 1495
K+ ++++ E+E+ + K L K++ + + ++E+ NK + K +LEK E
Sbjct: 4938 NKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQVIEEEKNKLEQMKIELEKEADE 4997
Query: 1496 L 1498
+
Sbjct: 4998 I 4998
Score = 91.3 bits (225), Expect = 2e-15
Identities = 138/568 (24%), Positives = 250/568 (44%), Gaps = 63/568 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL-----EAA 166
+ LE+ + + L +LL + D + + DR +LE K+ L+ DL E
Sbjct: 3639 ELLESDRKLLKKDVENLQQKLLIIESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE 3698
Query: 167 KTTLNDELERKK-DDNNAIIKKA----------LDKRISDLKADAPQRDQEDDMNALIXX 313
K L + ER++ ++ A I+K + + I D+K Q Q+ D
Sbjct: 3699 KIKLETQHERQRVEEMTAQIQKDREYLQKMNDNITREIHDIKYQEKQMKQKQDE------ 3752
Query: 314 XXXXXXXXXXXXXIVSNLEVNILILHEELQKEKD----DKTALIKDLVAAEPGKR--TVN 475
+ L+ I L +EL+KEK+ D++ L DL +E K+ +N
Sbjct: 3753 --------------LDQLKTEIQNLQQELEKEKEIIMKDRSEL--DLKQSELDKQQTNMN 3796
Query: 476 EIVSHLESKSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I+ ++++ + L K+ EE+ +E+ + + +E+L+ K K
Sbjct: 3797 DIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDEDLKMMKLQKQVF----- 3851
Query: 653 GCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCE------AE 808
E EK LE K LER A + + +EE++ E+ +TE + + AE
Sbjct: 3852 --EEEKNKLEQMKIELEREAGEIRKI----KEEIQNERQSLEKMTEELKREKESFTHLAE 3905
Query: 809 KQGPEKTVLD-LEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAK--NASLTDNQEGH 979
E+ +LD ++ SL LQ++ ++ + K+ D++ K N L +++ G
Sbjct: 3906 DTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLREDELGQ 3965
Query: 980 -EAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNN 1156
+AEI ++ E+ KEK + ES ER + V D++ +L+
Sbjct: 3966 LQAEIHKQQR--------EIEKEKSNIES----------ERAAIIKIVEDLQHKIISLDR 4007
Query: 1157 ELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHDIE-------MKTGKDDD 1303
+ + D EAF NER+ L+ +K LE+ ++E T HD + T + D
Sbjct: 4008 DAESLKLDREAFENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDK 4067
Query: 1304 YNEAEKQT------LKKRISELEEAI-SILTDK--AKKLLKDINIWLSEVTELQEDLNKE 1456
N ++T L ++ ++EE I SI +DK +K ++ SE+ +++EDL K+
Sbjct: 4068 INNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELYKVKEDLEKQ 4127
Query: 1457 --------SKEKQDLEKRVLELTSKLEK 1516
KE++DLEK +T ++ +
Sbjct: 4128 KENTLAEIQKEREDLEKMNENITIEMHE 4155
Score = 91.3 bits (225), Expect = 2e-15
Identities = 102/535 (19%), Positives = 239/535 (44%), Gaps = 32/535 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ E KQ +E + D + ++ +L+++
Sbjct: 5324 LDLRQSELDKQQTNVNDIMETMKNERKQLDKDKEETEEQKQEMEKEKHDFDQSRKSLDED 5383
Query: 188 LERKKDDNNAII--KKALDKRISDLKADAPQ--RDQEDDMNALIXXXXXXXXXXXXXXXI 355
L+ K + K L++ +L+ +A + + +E+ N +
Sbjct: 5384 LKMMKLQKQVLEDEKSKLEQMKIELEREAVEIRKIKEEIQNERQNLEKMTEALKEEREDL 5443
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK--EHFL 529
+ N +L E + ++++ E + +++ +E+K +L+ E L
Sbjct: 5444 AEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDEL 5503
Query: 530 REEEDEV------LERSASNL-----AIMKAIREEELR---KEKDGKSALVENGEGCEAE 667
R+ + E+ +E+ N+ AI+K + + + + ++D +S ++ E E E
Sbjct: 5504 RQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKIICLDRDAESLKLDR-EAFENE 5562
Query: 668 KQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
K+ L+ KT LER A ++ + E + +++V++ A + E E D+
Sbjct: 5563 KEVLKQMKTELEREADEIEKIKL--ETQHDRQRVEEMAAQIQKDRDEINNLIEETNRKDM 5620
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLT 1021
+ N ++ + + ++K LEK DLE + L +E E + E L
Sbjct: 5621 --VLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLA----- 5673
Query: 1022 HNDELHKEKDD----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
E+ KE++D E+I ++ +K + + + K +++ + + N Q+ + E
Sbjct: 5674 ---EIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEI 5730
Query: 1190 FLNERDGLEAVKQGLEKR---VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEA 1360
+ +R L+ + L+K+ + D+ T+ + + KD + E +KQ ++K ++++
Sbjct: 5731 IMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQS 5790
Query: 1361 ISILTDKAKKLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
L + KK+ ++ E +L++ +L +E+ E +++ +LEK
Sbjct: 5791 RKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQRLEK 5845
Score = 89.4 bits (220), Expect = 6e-15
Identities = 114/525 (21%), Positives = 236/525 (44%), Gaps = 44/525 (8%)
Frame = +2
Query: 56 DELLNEKDDK-----KCIVNDRNILEAAKQALE------YKVA-DLEAAKTTLNDELERK 199
D +LNEK+ K I +D+++LE K LE YKV DLE K E++++
Sbjct: 5619 DMVLNEKNRDIEEKIKSIQSDKDMLEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKE 5678
Query: 200 KDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
++D + + + + + ++K Q +Q+ D + L+ I
Sbjct: 5679 REDLEKM-NENITREMHEIKHQEEQMNQKQDE--------------------LDQLKTEI 5717
Query: 380 LILHEELQKEKD----DKTALIKDLVAAEPGKR--TVNEIVSHLESKSRSL-KEHFLREE 538
L +EL+KEK+ D++ L DL +E K+ +N+I+ ++++ + L K+ EE
Sbjct: 5718 QNLQQELEKEKEIIMKDRSQL--DLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEE 5775
Query: 539 EDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT------VLER 700
+ + +E+ N+ + +E+ +K K K E E K LE+ + E
Sbjct: 5776 QKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEE 5835
Query: 701 RASNLDTMDAIHEEELRKE----------KVDKSALTEN---GEGCEAEKQGPEKTVLDL 841
+ ++ + EE +R++ K +K L E E A+ Q + + ++
Sbjct: 5836 TQNKRQRLEKMTEELIREKESLAHLAEDTKTEKKILDEMKVANESSMADLQREKSILEEM 5895
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL-EASNL 1018
I L + + + ++ + L+K ++++ + + + + E+E + E N+
Sbjct: 5896 RENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNM 5955
Query: 1019 THNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
EL K+ +D E I+ + + + +R++L V +++ L + ++ D E
Sbjct: 5956 M--TELKKKSEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDRE 6013
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAIS 1366
AF NE++ ++ +K L+ + ++E I+++T D E ++K ++ I
Sbjct: 6014 AFENEKEAMKQMKTDLQIQADEIE----KIKLETQHDRQRVEEMAAQIQKERDKINNLIE 6069
Query: 1367 ILTDKAKKLLKDINIWLSE-VTELQEDLNKESKEKQDLEKRVLEL 1498
T++ +L + N + E + +Q D + KE+ +LEK EL
Sbjct: 6070 -ETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSEL 6113
Score = 87.8 bits (216), Expect = 2e-14
Identities = 122/538 (22%), Positives = 233/538 (43%), Gaps = 24/538 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E++ E A L E + + ++ I NDR E L+ + D+E + +
Sbjct: 2805 QIIEDERDKIEQIKAELQKEAKDTEKQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIR 2864
Query: 182 DE-------LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 340
DE +R + D + + K+ D + K + +D E + +
Sbjct: 2865 DEEANLRVLKQRLESDRDTLEKERFDLK----KTNTEMKDLEKQLESQNRQHEIQLAEIQ 2920
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 520
I+ L++ + E+L+KE+D D+ E E+ E +
Sbjct: 2921 KEREILEQLKLTLSKQKEDLEKERDCFEKEKADISLRE-------ELQEQSEREGIGKTR 2973
Query: 521 HFLREEEDEVLE------RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE 682
+++E DE+ + + N + K I E+E K + K+ L + E E +++ +E
Sbjct: 2974 VRIKKEMDELKQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAEDTEKQRRDIE 3033
Query: 683 K---------TVLERRASNLDT-MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTV 832
K L+ +++T D I +EE E V K L + + E E+ EKT
Sbjct: 3034 KDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLE-VQKQRLESDRDTLEKERFDLEKTK 3092
Query: 833 LDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE-RKLEA 1009
++ +L L+ + + + ++K LE +L+ +E E E + + E
Sbjct: 3093 TEM----GNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLSKQKEDLEKERDCFEKEK 3148
Query: 1010 SNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEA 1189
++++ +++L KE+ ++E I N +K E LE ++ NNELQ+K+ +
Sbjct: 3149 ADISLSEDL-KEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQE--NNELQKKIIE--- 3202
Query: 1190 FLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISI 1369
+ERD +E +K L+K EA +E+ +++ N E T K+ E E+++
Sbjct: 3203 --DERDKIEQIKAELKK-----EAEKTKLEL---QNERQNLEEAGTKLKKDRENVESLAE 3252
Query: 1370 LTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGL 1543
+ + +L+++ I TE+Q N+ +K+ Q+ RVL K I GA++ L
Sbjct: 3253 ELGRKQVVLENMQI----ETEMQRKANESNKQMQE---RVLIELKKTVTDIAGAKEDL 3303
Score = 85.9 bits (211), Expect = 7e-14
Identities = 116/534 (21%), Positives = 238/534 (44%), Gaps = 34/534 (6%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIV----NDRNILEAAKQALEYKVADLEAAKTTLND 184
K+ + + +A L+ EL KD+ + I +R+ +E + L ++ +E + D
Sbjct: 9979 KMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQIMQD 10038
Query: 185 ELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSN 364
+ ++ +I +K + +I + + Q +QE N L I N
Sbjct: 10039 KQNHLEEKELSIQRKEEEIKIGNTEF---QIEQEHLNNVLEETNKRQHDLEVMRADIELN 10095
Query: 365 LEVN------ILILHEELQKEKDD--------KTALIKDLVAAEPGKRTVNEIVSHLESK 502
+ N + + EL+ EK D K + L E K + ++ L+SK
Sbjct: 10096 KQKNNKDFELLEKIRSELENEKYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSK 10155
Query: 503 -SRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
++ KE + ++R + + + + + + K+ L E E + E++ L
Sbjct: 10156 REQTEKEKADLNRVNAEIQREKQVIDKKRHMTNRAMEELETIKTELKERQEKIQTEQEKL 10215
Query: 680 E--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E K +++ A NL+ + + + K ++ ++ L E CE ++ E+ D+E I
Sbjct: 10216 EEEKLLVQIEAENLNKVLEEIKRQQEKLEISEADLKVMKEQCENAREETERKKCDIEEQI 10275
Query: 854 PSLNDA---LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI--ERKL--EAS 1012
+ +A L+++ + +KQ L+K+ DL+ + + +N E + + E+KL + +
Sbjct: 10276 QNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVEMSKRSLDEEKKLLEQKA 10335
Query: 1013 N--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL---QQKMD 1177
N L D+L KEK+D N LD ++ E Q + +++ NE+ QQ+++
Sbjct: 10336 NEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLE 10395
Query: 1178 DNEAFLNERDG-LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELE 1354
++ +NE G LE ++ EK+ +E + +M E++ L + SELE
Sbjct: 10396 ESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKM-----------ERKELDQIKSELE 10444
Query: 1355 EAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ + + + KKL D N+ E +L++ ++ ++Q +E EL K+++
Sbjct: 10445 KDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKE 10498
Score = 85.5 bits (210), Expect = 9e-14
Identities = 103/492 (20%), Positives = 228/492 (46%), Gaps = 21/492 (4%)
Frame = +2
Query: 71 EKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALD 238
EKD K N++N+ L A + L+ + A++E K L + ++R + + I K+
Sbjct: 2487 EKDRLKLQENEQNMQMSQLNAKQNELDERQAEMEKQKRELENVMDRLEKEKVEITKEK-- 2544
Query: 239 KRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDD 418
+R+++++ + +++ D+ ++E + IL+ EL+K K+
Sbjct: 2545 QRVNEMQNEVKRKNASVDL------------IKQEVLREQDHIENSREILNRELEKIKEK 2592
Query: 419 KTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE 598
KT L ++ A + K + + + L L ++E E E+ ++ + E
Sbjct: 2593 KTILAEEFEALDDKKEMIGKEMQRLGKMKAEL------QKEAEDTEKQRRDIDNDRRNNE 2646
Query: 599 EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSAL 778
E + K ++ K + + + E+ L + +R S+ DT++ +L K K + L
Sbjct: 2647 EMVIKLQNEKKDIETSTDRIRDEEANL-RVQKQRLESDRDTLEK-ERFDLEKTKTEMKDL 2704
Query: 779 TENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASL 958
+ + E Q + + +E I + L++ + +K+ LEK E + A +
Sbjct: 2705 EK-----QLESQSRQHEIQLVE--IQKEREILEQLKINLSKQKEDLEKERDCFEKEKADI 2757
Query: 959 TDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETT 1138
+ +E E + ++ + + E+ + + + +++ +L++ + ++Q++E + +E
Sbjct: 2758 SLREELEEQSEKEGIDKTRVRIKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIE-- 2815
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTG--KDDDYN- 1309
+ ELQ++ D E +R +E ++ E+ V+ L+ DIE T +D++ N
Sbjct: 2816 --QIKAELQKEAKDTE---KQRQDIENDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANL 2870
Query: 1310 -------EAEKQTLKKRISELEEAISILTDKAKKL---LKDINIWLSEVTELQEDLNK-- 1453
E+++ TL+K +L++ + + D K+L + I L+E+ + +E L +
Sbjct: 2871 RVLKQRLESDRDTLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKEREILEQLK 2930
Query: 1454 --ESKEKQDLEK 1483
SK+K+DLEK
Sbjct: 2931 LTLSKQKEDLEK 2942
Score = 82.4 bits (202), Expect = 7e-13
Identities = 111/556 (19%), Positives = 242/556 (43%), Gaps = 54/556 (9%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADL----------- 157
EN + E + +++ N ++ K + +R ++ KQ L+ + DL
Sbjct: 10258 ENAREETERKKCDIEEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENV 10317
Query: 158 EAAKTTLNDELERKKDDNNAIIKKA--LDKRISDL-----KADAPQRDQEDDMNALIXXX 316
E +K +L++E + + N I+++ L+K D+ K D Q + +++ A+
Sbjct: 10318 EMSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIK 10377
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEE------LQKEKDDKTALIKDL-VAAEPGKRTVN 475
LE ++ ++EE ++ + + + I+++ V A+ ++ ++
Sbjct: 10378 YELDGKRNEINKEQQRLEESLRAINEEKGDLEIMRADYEKQEQQIEEMRVEAKMERKELD 10437
Query: 476 EIVSHLESKSRSLKEHFLREEEDE-VLERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
+I S LE + + + D ++E+ ++L MK+ + ++ +D +S L + +
Sbjct: 10438 QIKSELEKDKTEIDYEWKKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIK 10497
Query: 653 GCEAEKQGLEKT--VLERRASNLDTMD---AIHEEELRKEK---VDKSALTENGEGCEAE 808
EK +EK ++ER + ++ + +EEL E+ VD+ L CE E
Sbjct: 10498 EANTEKDKIEKNKEIVERLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQ---CETE 10554
Query: 809 KQGPEKTVLDLEPTIPSLNDAL-------QRD-------LDRVMAEKQALEKRCSDLEAK 946
Q + + ++E + + + L QRD ++ +K+ LEK + + +
Sbjct: 10555 LQNKSEQIRNMEEAVKNERETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQ 10614
Query: 947 NASLT---DNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLES- 1114
L D E EI K ++ + + KE + + ++ ER+ LE
Sbjct: 10615 KQELKNKKDTLEQEREEINHKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEV 10674
Query: 1115 --KVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKT 1288
K+ +M+T ++E+ QK+++ L+ +++ + K EA ++M
Sbjct: 10675 NGKIIEMKTKAELEHHEINQKIEE----------LQTLQEQIMKEKEKAEAMTIKLKM-- 10722
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEK 1468
E++ L + SEL + + + KKL DI + E +L++ ++ +K
Sbjct: 10723 ---------EREDLDQIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQK 10773
Query: 1469 QDLEKRVLELTSKLEK 1516
Q++EK EL +K+++
Sbjct: 10774 QEMEKERSELDNKIQQ 10789
Score = 82.0 bits (201), Expect = 1e-12
Identities = 117/523 (22%), Positives = 221/523 (42%), Gaps = 20/523 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N ++ E + +L E N +D+K + R+ + + A+ + DLE + E
Sbjct: 9663 LQNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGE 9722
Query: 188 LERKKDDNNAI------IKKALDKRISDLKADAPQRDQE--DDMNALIXXXXXXXXXXXX 343
+R +++ + IKK +D + + + R+++ + M L+
Sbjct: 9723 KKRMEEETRRLEMHREEIKK-VDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEE 9781
Query: 344 XXXIVSNLEVNILILHE---ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSL 514
L+ + L E+Q++ +DK I D+ E + EI L+ +++ L
Sbjct: 9782 IEKESQRLQDATIDLENAKAEIQRQ-EDKFEDIIDIKIQEKER----EIKIQLDKETKRL 9836
Query: 515 KEHFLREEEDEVLE-----RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGL 679
E + +D +E R + K + E+E ++ K K L + EKQ
Sbjct: 9837 SEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQET 9896
Query: 680 EKTVLERRASNLDTMDAIHEEELRKEKV--DKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
E+ A D E E+ KEK+ +KS + E +++ ++T + +
Sbjct: 9897 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKE- 9955
Query: 854 PSLNDALQRDLDRVMAEKQALEKRCSDL-EAKNASLTDNQEGHEAEIERKLEASNLTHND 1030
++L++ +KQ LE + + E KN ++E +A+ E LE N
Sbjct: 9956 ---KESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDE--LEKIAYKTNK 10010
Query: 1031 ELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDG 1210
E H+ + + + + + ++ + Q+++ K + +E ++ + ++ N F E++
Sbjct: 10011 ERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQRKEEEIKIGNTEFQIEQEH 10070
Query: 1211 LEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKK 1390
L V + KR DLE DIE+ K N + + L+K SELE
Sbjct: 10071 LNNVLEETNKRQHDLEVMRADIELNKQK----NNKDFELLEKIRSELENE---------- 10116
Query: 1391 LLKDINIWLSEVTELQE-DLNKESKEKQDLEKRVLELTSKLEK 1516
D+ IW + L E L + KEK+ LEK +EL SK E+
Sbjct: 10117 -KYDLQIWTEQQKHLVEVQLQELEKEKERLEKMEIELQSKREQ 10158
Score = 81.3 bits (199), Expect = 2e-12
Identities = 121/518 (23%), Positives = 225/518 (43%), Gaps = 20/518 (3%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + E +L+ +DDK + NDR+ E LE K
Sbjct: 9470 QDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELK-----------R 9518
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
+EL R+ +D + +K L +R D + +RD E+ AL
Sbjct: 9519 EELVRETED---LERKILQQREQD---EMAKRDIENQTEAL------------------E 9554
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
++V+IL E KE ++ V +E K + + L+S+ L+ EE+
Sbjct: 9555 VMKVDILKKRNEFAKEMEN--------VHSERQKLLL--LQGALQSQESELENRVFMEEQ 9604
Query: 542 DEVLERSASNLAIMKAIRE--EELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
+ + A K + E E + E++ L+E + E E+ + K +E+ +L
Sbjct: 9605 KHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEELQR-EKEQLEISKNQIEQEKKDL 9663
Query: 716 DTMDAIHE---EELRKEKV----DKSALTENGEGCEAEKQGPEKTVLDLE---PTIPSLN 865
M + E E LR EK +K+AL + + + K DLE I
Sbjct: 9664 QNMKSNLERQLESLRHEKANVEDEKNALEKMRSESKEIQNAIRKEREDLENCWVEIEGEK 9723
Query: 866 DALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELH 1039
++ + R+ ++ ++K S+L+ ++ +E ++E +++ +E+
Sbjct: 9724 KRMEEETRRLEMHREEIKKVDSELQKSRENIESREEKINNKMEELLQMKVEMGRTKEEIE 9783
Query: 1040 KEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 1219
KE + DL++ KAE Q E K D+ ++ ++Q+K + + L++ +
Sbjct: 9784 KESQRLQDATIDLENAKAEIQRQEDKFEDI------IDIKIQEKEREIKIQLDKE--TKR 9835
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYN---EAEKQTLKKRISELEEAISILTDKAKK 1390
+ + +E +V DLE + D++ + + +D E EKQ LK+ ELE+ + LT + ++
Sbjct: 9836 LSEEIELKVKDLEMEMADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQE 9895
Query: 1391 LLKDINIWLSEVTELQEDLNKES---KEKQDLEKRVLE 1495
++ N ++ +L EDL KE+ KEK LEK +E
Sbjct: 9896 TEEERNNLMALKNQL-EDLRKENEIVKEKLTLEKSNIE 9932
Score = 80.9 bits (198), Expect = 2e-12
Identities = 111/536 (20%), Positives = 231/536 (43%), Gaps = 46/536 (8%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K E +E+ EK+ ++ R +E ++ +E + LE ++ ++ E
Sbjct: 12356 ETKANILEMKTKAEPEEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQ 12415
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 12416 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDKKIKQTDLEKHDIENSKEIVE 12475
Query: 362 NLEVNILILHEELQKEK-----------DDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V + E+Q +K D++ LI++ + + + E+ ++ +
Sbjct: 12476 KLMVEVEKQKHEIQFQKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERE 12535
Query: 509 SLKEHFL-----REEEDEVLE---RSASNLAIMKAIREEELRKEKDGKSALVENGEGCEA 664
+LKE + +EE + V+E R +L M E+ + + + L + E
Sbjct: 12536 TLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQ-----ER 12590
Query: 665 EKQGLEKTVLERRASNLDTMDAI-----------HEEELRKEKVDKSALTENGEGCEAEK 811
E+ + T L++R +T I +E+L++ + ++ E E
Sbjct: 12591 EEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTEL 12650
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ E + ++ D L+++ E++ L+K+ DLE + D +E + +
Sbjct: 12651 EEIEVDQSQQNKNVETMKDLLEKERKDTEKEREELQKQADDLEMQMIEHGDKEEMSKRSL 12710
Query: 992 --ERKL--EASN--LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
E+KL + +N L D+L KEK+D N+LD ++ E Q ++++ +++ T
Sbjct: 12711 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNELDGLQKEIQNQKNEMEEIKCELETKR 12770
Query: 1154 NELQQKMDDNEAFLN----ERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKD-DDYNEAE 1318
E+ ++ E LN ER LE V+ EK + I ++ +KT + D+ ++
Sbjct: 12771 IEIIKEQKRLEESLNTVNEERQYLEIVRVDYEKH----QQQIEEMRVKTKMERDELDQLM 12826
Query: 1319 KQTL--KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLE 1480
+ L +K ++ I +L + ++ +++ ++ EL+ + K EK+DLE
Sbjct: 12827 AKMLMDRKENERSKDMIGLLKKEMEQTKFNLD---AQEEELKLEKQKIQNEKKDLE 12879
Score = 80.1 bits (196), Expect = 4e-12
Identities = 94/521 (18%), Positives = 225/521 (43%), Gaps = 46/521 (8%)
Frame = +2
Query: 92 IVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKR--------- 244
++N R++L+ ++ + +K L+ + ++ ++K+++ KK ++R
Sbjct: 12024 LMNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIK 12083
Query: 245 ISDLKADAP--------QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEEL 400
I ++K ++++E+ M A + I S LE + E
Sbjct: 12084 IIEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQ------IKSQLERVRSEIDHEQ 12137
Query: 401 QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAI 580
+K DDK + ++ E K + + +E + RS E+ +R+ E + S +
Sbjct: 12138 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEE-RSELENKIRQTYIEKCDIENSKEIV 12196
Query: 581 MKAIREEELRKEK----------------DGKSALVENGEGCEAEKQGLEKT--VLERRA 706
K + E E +K + D + L++N + E + ++ V+++
Sbjct: 12197 QKLMVEVEEQKHEIQFQKEELDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKER 12256
Query: 707 SNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
L M+A L KEK + ++TE + + + + + + + S D L+++
Sbjct: 12257 ETLKEMEAY----LEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQER 12312
Query: 887 DRVMAEKQALEKRCSDLEA-----------KNASLTDNQEGHEAEIERKLEASNLTHNDE 1033
+ + + + L++R + +A K + ++++ E LE +E
Sbjct: 12313 EEINHKWKQLQQRIDEFDAQVSKQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEE 12372
Query: 1034 LHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGL 1213
+ KEK+ +E V+ ER+ +E S +E S +++E ++ DD + E++ L
Sbjct: 12373 IKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERVRSEMDHEQKKLNDDKKMIEQEKEDL 12432
Query: 1214 EAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKL 1393
E +K + K+ +E +++ K K D + + + K+ + +L + + +
Sbjct: 12433 EKMKSEIMKQRQQMEEERSELDKKI-KQTDLEKHDIENSKEIVEKLMVEVEKQKHEIQFQ 12491
Query: 1394 LKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++++I ++ + Q+ L + E+Q+ +R+ E+ +++K
Sbjct: 12492 KEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKK 12532
Score = 79.3 bits (194), Expect = 6e-12
Identities = 122/575 (21%), Positives = 250/575 (43%), Gaps = 74/575 (12%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
E K+ E T +++ EK+ ++ V R +E K+ L+ + LE ++ ++ E
Sbjct: 11801 ETKIKIIEMKTKTEPEKIKKEKEKEEEEVM-RAKVEMKKEELDQIKSQLERVRSEIDHEQ 11859
Query: 191 ERKKDDNNAII--KKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVS 361
++ DD I K+ L+K S++ Q ++E +++ I IV
Sbjct: 11860 KKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQ 11919
Query: 362 NLEV-------NILILHEEL----QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
L V +I + EEL QK D++ ++++ + + E+ ++ +
Sbjct: 11920 KLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKE 11979
Query: 509 SLKE---HFLREEED-------------EVLERSASNLA-----------IMKAIREE-- 601
+LKE H +E+E+ E LE+ ++++ ++K REE
Sbjct: 11980 TLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREEIN 12039
Query: 602 ----ELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE--KV 763
+L++ D A V + + KQ K + E R S +T I E + + E K+
Sbjct: 12040 HKWTQLQQRIDEFDAQVSKQKEEDLTKQ---KKMEEERKSLEETKIKIIEMKTKTEPEKI 12096
Query: 764 DKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEA 943
K E E A+ + ++ + ++ + + + + ++ +K+ +E+ DLE
Sbjct: 12097 KKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEK 12156
Query: 944 KNASLTDNQEGHE---AEIERKLEASNLTHND-ELHKE---------KDDKESIMNDLDH 1084
+ + ++ E +E+E K+ + + D E KE ++ K I +
Sbjct: 12157 MKSEIMKQRQQMEEERSELENKIRQTYIEKCDIENSKEIVQKLMVEVEEQKHEIQFQKEE 12216
Query: 1085 VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEAT 1264
+ ERQ + + + S L NE ++ + NE ER+ L+ ++ LEK ++++
Sbjct: 12217 LDIERQKIADEQDLLIQNKSELQNENERIKNINEVIKKERETLKEMEAYLEKEKEEMKSI 12276
Query: 1265 IHDIEMKTGKDD-----DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVT 1429
E + K+D + +KQ L+ + LE+ + K K+L + I+ + ++V+
Sbjct: 12277 TE--ETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEFDAQVS 12334
Query: 1430 -ELQEDLNKESKEKQD------LEKRVLELTSKLE 1513
+ +EDL KE + K+D + +LE+ +K E
Sbjct: 12335 KQKEEDLPKEKEMKEDRKSLEETKANILEMKTKAE 12369
Score = 78.6 bits (192), Expect = 1e-11
Identities = 115/572 (20%), Positives = 245/572 (42%), Gaps = 91/572 (15%)
Frame = +2
Query: 56 DELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEAAKTTLND----------ELE 193
+EL E+ D + D +N L+ K A E +ADL+ K+ L + ++E
Sbjct: 6721 EELKKERKDVAHLAEDTKREKNSLDEMKVANESSMADLQKEKSNLEEMKENISKQTEDIE 6780
Query: 194 RKKD------DNNAIIKKALDKRISDLKADAPQRDQE--------DDMNALIXXXXXXXX 331
++KD D ++ + K+ S+ + + ++E +D+ + I
Sbjct: 6781 KEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 6840
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH----LES 499
N + + + EL++E D+ + K + + ++ V E+ + + +
Sbjct: 6841 SLKLDREAFENEKEELKQMKTELEREADE---IEKIKLETQHERQRVEEMTADFMETMNN 6897
Query: 500 KSRSL-KEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQG 676
+ + L K + EE+ + +E+ ++ + +E+L+ K K L E E K G
Sbjct: 6898 ERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIG 6957
Query: 677 LE---------KTVLERRASNLDTM-DAIHEE------ELRKEKVDKSALTENGEGCEAE 808
LE K + NL+ M +A+ EE E++++ + E A+
Sbjct: 6958 LEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANESTLAD 7017
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAE 988
Q ++ + ++ I + ++ + ++ + L+K ++++ + + + + E+E
Sbjct: 7018 LQKEKRILEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESE 7077
Query: 989 IERKL-EASNLTHNDELHKEKDDKE----SIMNDLDHVKAERQVLESKVSDMETTYSTLN 1153
+ E N+ EL K+ +D E I+ + + + +R +L+ V D++ ++
Sbjct: 7078 RAAMIREKQNMM--TELKKKSEDVEMQMKEILTEKELLHNDRNLLKKDVEDLQQKLMSIE 7135
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE----ATIHD---IEMKTGK------ 1294
+ + D EAF NE++ ++ +K L+ + ++E T H+ +E KT +
Sbjct: 7136 RDSESLKLDKEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKERE 7195
Query: 1295 ----------------DDDYNE--AEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS 1420
D+ Y E EK+ ++ S+LE+A S + K K+I I L+
Sbjct: 7196 EINTLVEEIKKKRDIIDESYTEIRKEKEAIESDRSDLEKAKS----QTFKQNKNIEIALA 7251
Query: 1421 EVTELQEDLNKESKE------KQDLEKRVLEL 1498
E+ + + L K SKE K + EK+ ++L
Sbjct: 7252 EIQQKRNALEKMSKEISRDRMKLEDEKKEIQL 7283
Score = 77.8 bits (190), Expect = 2e-11
Identities = 109/519 (21%), Positives = 218/519 (42%), Gaps = 22/519 (4%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKC-----------IVNDRNILEAAKQALEYKVADLEAAKT 172
+ I+ +++ NEK+ K + ++ ++ K +E + A + K
Sbjct: 4354 EMRENISKQTEDIENEKEKSKLREDELKKLQTEVQKQQSEIDMEKTNIESERAVMIREKQ 4413
Query: 173 TLNDELERKKDDNNAIIKKAL-DKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXX 349
+ EL++K +D +K+ L +K + + ++ ++D ED L+
Sbjct: 4414 NMMTELKKKSEDVEIQMKEILTEKELLENDSNLLKKDMEDLKQKLMSIERDSESLKLDRE 4473
Query: 350 XIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFL 529
+ EV + + +LQ + D+ + K + + ++ V E + ++ K R
Sbjct: 4474 AFGNEKEV-LKQMKTDLQIQADE---IEKIKLETQHDRQRVEEKTAQIQ-KDRD------ 4522
Query: 530 REEEDEVLERSASNLAIMKAIR--EEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLE 697
E + ++E + ++ + + R EE+++ + K L E E+ LEKT L
Sbjct: 4523 -EINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDML-------EKERHNLEKTRSELA 4574
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQ 877
R NL+T I +++ K K + S + E + + + + L+ I +L L+
Sbjct: 4575 RAKENLETQREIERKDIEKMKKNISREMHEIKHQEEQMKQKQDELDQLKTEIQNLQQELE 4634
Query: 878 RDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER--KLEASNLTHNDELHKEKD 1051
++ + +M + L+ R S+L+ + ++ D E + E ++ K + E+ KEK
Sbjct: 4635 KEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEETEEQKQEMEKEKH 4694
Query: 1052 D----KESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEA 1219
D ++S+ DL +K ++QV+E + S ++ L E + E NER E
Sbjct: 4695 DFDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEK 4754
Query: 1220 VKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLK 1399
+ + L+K DL D + K D+ A + TL
Sbjct: 4755 MTEALKKEREDLS---EDAKRKNQVLDEMKVANESTLA---------------------- 4789
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
DI L E + LQE SK+ +D+E + ++ + EK
Sbjct: 4790 DI---LRERSNLQEMRENISKQTEDVENKKEKIRLREEK 4825
Score = 77.8 bits (190), Expect = 2e-11
Identities = 108/524 (20%), Positives = 230/524 (43%), Gaps = 31/524 (5%)
Frame = +2
Query: 38 TIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL---NDELERKKDD 208
T+ + L EK++ K I + K+ LE D++ L D LE++K+D
Sbjct: 10866 TLKEMEAHLEKEKEEMKSITEETR---RQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKED 10922
Query: 209 NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILIL 388
N + L +RI + A ++ +ED I + + +
Sbjct: 10923 INHEWTQ-LQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAELEDI 10981
Query: 389 HEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE--VLERS 562
+E +KE++++ +K E + ++ I S L+ + RS +H ++ D+ ++E+
Sbjct: 10982 KKEKEKEEEEEEMRVK----VEMDGKELDRIKSELK-RERSEIDHEQKKLNDDKKIIEQE 11036
Query: 563 ASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEE 742
NL MK+ ++ ++ ++ +S L + EK +E + + ++ + HE
Sbjct: 11037 KQNLEKMKSEIMKQRQQMEEERSELENKIKQTYIEKCDIENSKEIVQKLMVEVEEQKHEI 11096
Query: 743 ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEK 922
+ +KE++D E+Q + D + + LQ + +R+ + ++K
Sbjct: 11097 QFQKEELD------------IERQ----KIADEQDLLIQNKSELQNENERIRNLNEIIKK 11140
Query: 923 RCSDLEAKNASLTDNQEGHEAEIE--RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAE 1096
L+ A L +E ++ E R+L+ + +++K+ D +MN D ++ E
Sbjct: 11141 ERETLKEMEAHLEKKKEEIKSVSEETRRLKEDLEKMSTDVNKQNKD---LMNQRDLLEQE 11197
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ-GLEKRVLDLEAT-IH 1270
R+ + K +LQQ++D+ +A ++++ + K+ G+++ LE T +
Sbjct: 11198 REEINHKWK-----------QLQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKAN 11246
Query: 1271 DIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLL------------------ 1396
IEMKT + + + EK+ + E EE I ++ + +K L
Sbjct: 11247 VIEMKTKAEPEEIKKEKEKENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQ 11306
Query: 1397 KDINIWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEK 1516
K +N ++ + + +EDL K K++Q +E+ EL +K+++
Sbjct: 11307 KKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQ 11350
Score = 76.6 bits (187), Expect = 4e-11
Identities = 112/520 (21%), Positives = 215/520 (41%), Gaps = 22/520 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAA------- 166
+EN F+ IA L + K DK+ I N+ L+ +Q E + + +
Sbjct: 15017 IENITVTFKRNIAQLETTIAMMKKDKENIENELLQLKQTEQEREIQRGTDDTSNERENYD 15076
Query: 167 -----KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXX 331
KT L D E+KK D ++ +K ++D AD+ + D E + L
Sbjct: 15077 EKVTYKTELEDSKEKKKPDRDSSLK------LTD--ADSAKTDGEREAQTL--------- 15119
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
V L EEL E ++K +I +L A+ + + L+ + RS
Sbjct: 15120 --ETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAK-------KDLQKLKEECRS 15170
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KT 688
+E + E LER ++L E+++ E + +++ + E Q +E K
Sbjct: 15171 AEEE--KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKM 15220
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPS--- 859
++ R+ + ++ ++ +T+ E + K+ + TV LE T+ S
Sbjct: 15221 QIQTRSVATQWETDVQIQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDTLTSEVQ 15280
Query: 860 -LNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDEL 1036
+ D+L ++++ V K ++ LE + + E E +E +E + + ++L
Sbjct: 15281 EMRDSLNKEMEDVARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKS-RNEEKL 15339
Query: 1037 HKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNER 1204
+ DKE + N LD ++ + K++ +ETT + +
Sbjct: 15340 LQLTHDKEDLSNTLDKKNKEIENNTETSLKKIAQLETTIVLMKKD--------------- 15384
Query: 1205 DGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDK 1381
K+ +E +L L+ T + E++ G DD NE EK K +ELE+ +
Sbjct: 15385 ------KENIENELLQLKQTEQEREIQRGTDDTSNEREKYDEKVTYKTELED-----NKE 15433
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
KK +D ++ L++ + D +E++ + + VL+LT
Sbjct: 15434 KKKPDRDSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 15473
Score = 76.3 bits (186), Expect = 5e-11
Identities = 125/547 (22%), Positives = 241/547 (44%), Gaps = 47/547 (8%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT---TLNDE 187
K+AD + + EL NE + I N I++ ++ L+ A LE K ++++E
Sbjct: 11109 KIADEQDLLIQNKSELQNENER---IRNLNEIIKKERETLKEMEAHLEKKKEEIKSVSEE 11165
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R K+D L+K +D+ +D + + L +
Sbjct: 11166 TRRLKED--------LEKMSTDVNKQ--NKDLMNQRDLLEQEREEINHKWKQLQQRIDEF 11215
Query: 368 EVNILILHEE-LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES---KSRSLKEHFLRE 535
+ + E+ L KEK K +D + E K V E+ + E K KE+ E
Sbjct: 11216 DAQVSKQKEQDLPKEKGMK----EDRKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEE 11271
Query: 536 EEDE----VLERSASNLAIMKAIREEELRKEKDGKSA-LVENGEGCEAEKQGLEKTV--- 691
EE+E ++E L +K+ E +R E D + L + + E EK+ LEK
Sbjct: 11272 EEEEEIRVIVETERKELYQIKS-ELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEI 11330
Query: 692 ------LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPE----KTVLDL 841
+E S LD + I + L K ++KS E E+Q + K LD+
Sbjct: 11331 MKQRQQMEEERSELD--NKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDI 11388
Query: 842 E-PTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNL 1018
E I + L ++ ++ E + ++K +++ + +L E EI K E L
Sbjct: 11389 ERQKIADEQNLLVQNKAKLQNENERIKKVDEEIKKERETL------REMEIHLKKEKEEL 11442
Query: 1019 THN-DELHKEKDDKESIMNDLD----HVKAERQVLESKVSDMETTYSTLNNELQQKMDDN 1183
+E + K+D E + D++ H+K +R +LE + ++ + +LQQ++D+
Sbjct: 11443 RSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDLLEQEREEINHEMT----QLQQRIDEF 11498
Query: 1184 EAFLNE------RDGLEAVKQGLEK---RVLDLE--ATIHDIEMKTGKDDDYN-----EA 1315
+A +++ + +E ++ LE+ R+++++ A + +I + ++D+ E
Sbjct: 11499 DAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVEM 11558
Query: 1316 EKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLE 1495
E++ L + SEL+ S + + KKL D I E +L++ ++ ++Q +E+ E
Sbjct: 11559 EREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSE 11618
Query: 1496 LTSKLEK 1516
L +K+++
Sbjct: 11619 LDNKIKQ 11625
Score = 75.9 bits (185), Expect = 7e-11
Identities = 111/513 (21%), Positives = 213/513 (41%), Gaps = 67/513 (13%)
Frame = +2
Query: 179 NDELERKKDD-NNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXI 355
ND +E+ ++D NNA+ K +D+ D++ QE A++ I
Sbjct: 1457 NDRVEQMREDVNNAL--KDIDQAKEDIQRQREVIAQEKVQPAIVATKSSEYAKTEEPGAI 1514
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLRE 535
S + L L +QKE+ + K+++ E K +N+I +++ +E ++
Sbjct: 1515 KS-YRASDLELSASIQKERQELEHY-KEIILKE--KHELNKIKEDVKAVKNDAEERMIKL 1570
Query: 536 EEDEVLERSASNLAIMKAIREEELRKEKD--GKSALVENGEGCEAEKQGL---------E 682
E+E E +++ R+ + KEK+ G A+ + KQ L E
Sbjct: 1571 HEEEK-EMKTKRVSLQNWERQLQTEKEKNQKGLDAIWNENQQLNERKQQLDIKELHLQSE 1629
Query: 683 KTVLERR-------------------ASNLDTMDAIHEEELRKEKVDKSALTENGEGCEA 805
K+ LE + AS D +I E + +++ ++ + C
Sbjct: 1630 KSKLEYKKPLEIKQVDAQVQTELMEDASEYDMALSIEELDKQRQFLEYFKQELLAQKCTM 1689
Query: 806 EKQGPE-------------------KTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRC 928
E+Q E +T D+E + L++ D + K ++K
Sbjct: 1690 ERQMAEIELSRDELSLREATLQTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGW 1749
Query: 929 SDLEAKNASLTDNQEGHEAEIERKLEASNLTHND-ELHK---EKDDKESIMNDLDHVKAE 1096
DL+ + A + +E E+E+ + N D E K E D K ++ + ++++A+
Sbjct: 1750 VDLQTQIAESREKEEMVRIELEKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ 1809
Query: 1097 RQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDI 1276
R+++E + +E L E +ER +E + L++ +LE HD+
Sbjct: 1810 RKMMEDEKRALENMKYELQRESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDM 1869
Query: 1277 EM------KTGKD-DDYNEAEKQTLK--KRISELEEAISILTDKAKKLLKD----INIWL 1417
+ + KD ++ E + TL K S++ E IS L + K +++ I I
Sbjct: 1870 QQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIRE 1929
Query: 1418 SEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
++ ++Q DLN++ KE QD++ V S+L+K
Sbjct: 1930 YDLQQMQTDLNRQQKEMQDIQNAVFMEKSELKK 1962
Score = 75.5 bits (184), Expect = 9e-11
Identities = 110/522 (21%), Positives = 225/522 (43%), Gaps = 35/522 (6%)
Frame = +2
Query: 5 ALENKVADFE---ATIATLNDELLNEKDDKKCIVND----RNILEAAKQALEYKVADLEA 163
A + + DFE I N EL ++++ K + + R LE + + +V +
Sbjct: 7462 AFQMEKTDFERIKTEIDQANKELADQQEKNKKTITEMQKERETLEEMRANISKQVETITN 7521
Query: 164 AKTTLND---ELERKKDD-----------NNAIIKKA--LDKRISDLKADAPQRDQEDDM 295
+L+ EL + ++D N I+ + LD+R SD+ D Q++ +D M
Sbjct: 7522 ENKSLSSRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDI--DLLQKEVDDLM 7579
Query: 296 NALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVN 475
+ ++N+E L + + + K D +L + A E + +N
Sbjct: 7580 D--------------FTKTEMANVERERLEVLAQTRNIKSDMVSLKMEKEACEQLRLKLN 7625
Query: 476 EIVSHLESKSRSLKEHFLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E +E + L ++ ++D++ ++R NL + K + E ++ + K +L
Sbjct: 7626 EEKDLIEKERELLTKNLDHTDKDKMDMKRELENLKVEKETIKNEKKELEKMKISLQRKAI 7685
Query: 653 GCE--AEKQGLEKTVLERRASN----LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQ 814
G + +EK E+ ++E A+ LD + E + +E++D++ +
Sbjct: 7686 GFKEFSEKTKDERPIVEEMAAQFTRQLDISERPAEGKFIEERLDQTEKKRRKTYYTEDLF 7745
Query: 815 GPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIE 994
EKT DL+ T +N D + + ++ L K E E
Sbjct: 7746 QEEKT--DLQKTKEEIN----YDREEIYRQRTELNK-------------------EKETL 7780
Query: 995 RKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKM 1174
+++ SNL + + KEK+ + N+LD ++AE L++K DM+ T + + E +
Sbjct: 7781 KQMHTSNLKEIENIEKEKEKIQRTWNELDQIRAE---LQNKQRDMDDTTNIMMKEKAELA 7837
Query: 1175 DDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQ---TLKKRIS 1345
D E NE+D L+ ++ ++K + +L+ E + + N+ +Q +K +
Sbjct: 7838 RDLENLQNEKDELQKSRENIQKLMKELQ------EERLKTSEALNKERQQFTEEIKLKND 7891
Query: 1346 ELEEAISILTDKAKKLLKDINIWLSEVTELQ--EDLNKESKE 1465
L+E + + + + L+ D I ++ +LQ +D+ ++S E
Sbjct: 7892 SLDEIQAEIDRQKRALVTDKEIITKQMMDLQKTQDVRRQSDE 7933
Score = 75.5 bits (184), Expect = 9e-11
Identities = 105/540 (19%), Positives = 219/540 (40%), Gaps = 57/540 (10%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
IA + D+LL EK+D +E K+ + + +E ++ LND+ E +N +
Sbjct: 13675 IADMKDQLLKEKED----------VETTKERINREKEHIEKMQSQLNDQKEEMDLENQKL 13724
Query: 221 I---------KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEV 373
+ AL+K + DL+ + +++NAL+ E
Sbjct: 13725 LYMKTEIQVKTNALEKMMQDLQKE------RENVNALVIQHQ-------------KEREQ 13765
Query: 374 NILILHEELQKEKDDKTALIKDLVAAEPGK-------RTVNEIVSHLESKSRSLKEHFLR 532
+++ E +KEK + + + E K ++++ S L+++S L E+ ++
Sbjct: 13766 RDILIEENKRKEKHAEAEIQRQFEDIESVKVRLVTESNQIDKMNSELKTRSEEL-ENLIK 13824
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASN 712
+++ E + KA+ E++ E + KS ++N + EK + + L++ +
Sbjct: 13825 KQQKEFETKENEMQRERKAL--EKMNAELERKSTELKN----KIEKVTVWEADLQKEKNK 13878
Query: 713 LDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDR 892
+ + I E E + +K+ + + E ++ + + +LE L D + L R
Sbjct: 13879 TEELKNILEREKSELYQEKAQVQQQKHEMETIRKTMKSEMENLECLRNELEDEKKSMLSR 13938
Query: 893 VMAEKQALEKRCSDLEAKNAS----------LTDNQEGHEAEIERKLEASNLTHNDELHK 1042
+ EK ++K ++++++ S L D E +++ +E N+ + +
Sbjct: 13939 LSMEKHEIDKLKTEIQSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLS-IQR 13997
Query: 1043 EKDDKESIMNDL----------------------------DHVKAERQVLESKVSDMETT 1138
EKD E I DL D + + + L S +D+E
Sbjct: 13998 EKDSLEEIKADLQRKAEKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQ 14057
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
L +++Q L+ K+ LEK + + D+E K N+
Sbjct: 14058 AKILESDVQL--------------LQTEKEILEKSKTENDLLREDLE----KQRKRNDLT 14099
Query: 1319 KQTLKKRISELEEAISILT---DKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
Q L+K LE+ I+ +T D L ++++ E+ + +L+++ KE DL ++
Sbjct: 14100 LQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNKETELDEQRKEMDDLRMQL 14159
Score = 74.3 bits (181), Expect = 2e-10
Identities = 122/611 (19%), Positives = 247/611 (40%), Gaps = 64/611 (10%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELER 196
+V + L E+ ++ K ++++ I ++ Q L + + L E+E
Sbjct: 9064 EVVKIREMVRNLKGEMERRMEESKVEIDEKEIFKSEIQRLIQDIGQIRENLGGLKTEIEN 9123
Query: 197 KKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVN 376
K D K L+K ++L + Q+++E L ++E++
Sbjct: 9124 TKRD-----KSNLEKMKAEL--EEKQQEEESMREILQKEKEELEQLKKDINREKEDIEIS 9176
Query: 377 ILILHEEL-----------QKEKDDKTALIKDLVAAEPGKRTVNEIVSHLES-------- 499
++ E+ QK K++ + ++L+ + +N V HL
Sbjct: 9177 RELVESEIYEGEVKGFTDVQKYKEELQIVTEELLTKKRNLEQLNSDVQHLMQTLEEVDIQ 9236
Query: 500 --KSRSLKEHFLRE--EEDEVLERSASNL--------------AIMKAIREEELRKEKDG 625
K ++ EH E + +++LE+ L +++I E L+K +D
Sbjct: 9237 YIKKKAELEHITSEIQKREQILEKQKKKLEENGWIIEEIEMMKVTLESINMEILQKRED- 9295
Query: 626 KSALVENGEGCEAEKQGLE--KTVLERRASNLDT--MDAIHEEELRKEKVDKSALTENGE 793
+ + E EKQ E + L+R+ +++ I E++ K K+D E
Sbjct: 9296 ---MEKEKENLRREKQETELFRGELQRQRDEVESSRQALIMEKDQFKLKIDHQR-NEMSA 9351
Query: 794 GCEAEKQGPEKTVLDLE----PTIPSLNDA------LQRDLDRVMAEKQALEKRCSDLEA 943
E E + E DLE SLNDA LQ+ + + EK+ +E+ ++
Sbjct: 9352 AFEKEHKRLENMENDLENQRAKLAESLNDAAKMEQKLQQMKNELNKEKEQVEEMKQMVKT 9411
Query: 944 KNASLTDNQE-----------GHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLD-HV 1087
+ + +E GHE ++++K E + D+L ++ + + + DL +
Sbjct: 9412 ERVKIEQEKEEMRKQTQEIEDGHE-KLQKKTEIA-----DKLLQDANSESDRLKDLSMKL 9465
Query: 1088 KAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATI 1267
+ +RQ +E ++MET +L+ ++ DD N+RD E LE + +L
Sbjct: 9466 QMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELVRET 9525
Query: 1268 HDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDL 1447
D+E K + + +E K+ ++ + LE + K + K++ SE +L
Sbjct: 9526 EDLERKILQQREQDEMAKRDIENQTEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQ 9585
Query: 1448 NKESKEKQDLEKRV-LELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPFEDLVQGF 1624
++ +LE RV +E L++ + + E MS+ + + + L++
Sbjct: 9586 GALQSQESELENRVFMEEQKHLKQAKAETEECRKQLAE--MSETVTTEQ-NEYRKLIEEL 9642
Query: 1625 SRKTSPLDITK 1657
R+ L+I+K
Sbjct: 9643 QREKEQLEISK 9653
Score = 73.9 bits (180), Expect = 3e-10
Identities = 115/530 (21%), Positives = 227/530 (42%), Gaps = 26/530 (4%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
Q +E + DF+ + +L+++L K K+ I +++ L+ K LE + ++ K
Sbjct: 4687 QEMEKEKHDFDQSRKSLDEDLKMMKLQKQVIEEEKSKLKQMKIELEREADEIRKVKEETQ 4746
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIV 358
+E + + + +AL K DL DA +++Q D+M V
Sbjct: 4747 NERQIFEK-----MTEALKKEREDLSEDAKRKNQVLDEMK-------------------V 4782
Query: 359 SNLEVNILILHEE--LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR 532
+N IL E LQ+ +++ + +D+ + R E + L+++ + +
Sbjct: 4783 ANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQQSETEK 4842
Query: 533 EEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE--KTVLERRA 706
E+ + ER+A + ++ ++ + + ++D +S ++ E E EK+ L+ KT LER A
Sbjct: 4843 EKSNIERERAAI-IKDVEDLQSKIISLDRDAESLKLDR-EAFENEKEELKQMKTELEREA 4900
Query: 707 SNLDT--MDAIHEEELRKEKV---------DKSALTENGEGCEAEKQGPEKTVLDLEPTI 853
++ ++ HE + +E ++ L +N E + +KQ EK D++ +
Sbjct: 4901 DEIEKIKLETQHERQRVEEMTADFMETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSR 4960
Query: 854 PSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDE 1033
SL+ ++L + +KQ +E+ + LE L EA+ RK++
Sbjct: 4961 KSLD----KNLKMMKLQKQVIEEEKNKLEQMKIELEK-----EADEIRKIKEETQNERQR 5011
Query: 1034 LHKE----KDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE 1201
L K K +KES + + K E+++L+ M+ +L +LQ+ E
Sbjct: 5012 LEKMTEELKKEKESFTHLAEDTKTEKKILDK----MKVANESLMADLQK----------E 5057
Query: 1202 RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDK 1381
+ LE +++ + K+ D +E EK+ ++ R ELE+
Sbjct: 5058 KSNLEEMRENISKQTED------------------SEKEKEKIRLREDELEQ-------- 5091
Query: 1382 AKKLLKDINIWLSEVTELQEDLNKES------KEKQDLEKRVLELTSKLE 1513
L +I+ E+ E N ES K+ +DL+ ++ L LE
Sbjct: 5092 ---LQAEIHKQQGEIK--MEKSNNESERAAIIKDVKDLQHKMFSLDRDLE 5136
Score = 73.6 bits (179), Expect = 3e-10
Identities = 109/526 (20%), Positives = 232/526 (44%), Gaps = 23/526 (4%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+N+ D E + + DE N + K+ + +DR+ LE + DLE KT + +
Sbjct: 3046 LQNEKKDIETSTDRIRDEEANLEVQKQRLESDRDTLEKER-------FDLEKTKTEMGN- 3097
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
+KK L+ +I + + +E + I+ L
Sbjct: 3098 -----------LKKQLESQIRQHEIQLVEIQKERE--------------------ILEQL 3126
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGK-RTVNEIVSHLESKSRSLKEHFLREEED 544
++N+ E+L+KE+D D+ +E K ++ E + + ++ +++E D
Sbjct: 3127 KINLSKQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTR--------IKQEMD 3178
Query: 545 EVLERSASNLA-------IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERR 703
E LE++ NLA + K I E+E K + K+ L + E + E Q E+ LE
Sbjct: 3179 E-LEKTRQNLAKEQENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQN-ERQNLEEA 3236
Query: 704 ASNL----DTMDAIHEEELRKEKVDKSALTE---NGEGCEAEKQGPEKTVLDLEPTIPSL 862
+ L + ++++ EE RK+ V ++ E + E+ KQ E+ +++L+ T+ +
Sbjct: 3237 GTKLKKDRENVESLAEELGRKQVVLENMQIETEMQRKANESNKQMQERVLIELKKTVTDI 3296
Query: 863 NDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHK 1042
A + ++++ E++ + + ++++A+ L ++G E++++ N T L +
Sbjct: 3297 AGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGIS---EQQVDIVNKTEQLRLRE 3353
Query: 1043 EKDD--KESIMNDLDHVKAERQVL---ESKVSDMETTYSTLNNELQQKMDDNEAFLNERD 1207
+ + + I D ++A R+ + + ++ +T L E+ Q M+ +D
Sbjct: 3354 VELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMME-----YASKD 3408
Query: 1208 GLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAK 1387
+ LEK ++ A H ++++ K+ E Q L E+++ + L + K
Sbjct: 3409 -----RANLEKEKSEMIAQKHQMDIELNKERGLIEERTQMLNTYEKEMDQKRTALEVEMK 3463
Query: 1388 KLLKDINIWLSEVTELQE---DLNKESKEKQDLEKRVLELTSKLEK 1516
+L E +LQ+ +L +E+ + + L+++ LEK
Sbjct: 3464 ELKYHKQAIQEEKNKLQQMKIELQREADDIKKLKEKTRNERQSLEK 3509
Score = 73.6 bits (179), Expect = 3e-10
Identities = 118/636 (18%), Positives = 269/636 (42%), Gaps = 68/636 (10%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ K ++ + +ND + K+++K + D+ +E K+ +E + D + + +L+++
Sbjct: 3781 LDLKQSELDKQQTNMNDIIETMKNERKQLDKDKEEMEEQKREIEKEKHDFDQGRNSLDED 3840
Query: 188 LERKK-------DDNNAI--IKKALDKRISDLKADAPQRDQE--------DDMNALIXXX 316
L+ K ++ N + +K L++ +++ + E +++
Sbjct: 3841 LKMMKLQKQVFEEEKNKLEQMKIELEREAGEIRKIKEEIQNERQSLEKMTEELKREKESF 3900
Query: 317 XXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLE 496
I+ ++V L ELQKEK + + +++ + E + E
Sbjct: 3901 THLAEDTKKEQEILDEIKVANESLMAELQKEKSNFEEMRENISKQTEDVKNKKENLRLRE 3960
Query: 497 SKSRSLKEHFLREEEDEVLERS------ASNLAIMKAIREEELRKEKDGKSALVENGEGC 658
+ L+ +++ + E+S A+ + I++ ++ + + ++D +S ++ E
Sbjct: 3961 DELGQLQAEIHKQQREIEKEKSNIESERAAIIKIVEDLQHKIISLDRDAESLKLDR-EAF 4019
Query: 659 EAEKQGLE--KTVLERRASNL-------------------------DTMDAIHEEELRKE 757
E E++ L+ KT LER + D ++ + EE RK+
Sbjct: 4020 ENEREVLKQMKTELERETDEIEKIKLETQHDRQRVEEMTAQITKERDKINNLIEETNRKD 4079
Query: 758 KV--DKS--------ALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEK 907
V +K+ ++ + + E EK EKT +L + + L++ + +AE
Sbjct: 4080 MVLNEKNRDIEEKIKSIQSDKDMLEKEKHNLEKTRSELY----KVKEDLEKQKENTLAE- 4134
Query: 908 QALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD-----KESIMN 1072
++K DLE N ++T +E + H +E K+K D K I N
Sbjct: 4135 --IQKEREDLEKMNENIT-------------IEMHEIKHQEEQMKQKQDELDQLKTEIQN 4179
Query: 1073 DLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLD 1252
++ E++++ S+++ S L+ + D E NER L+ K+ +E++ +
Sbjct: 4180 LQQELEKEKEIIMKDRSELDLRQSELDKQQTNMNDIIETMKNERKLLDKDKEEMEEQKQE 4239
Query: 1253 LEATIHDIEMK-TGKDDDYN--EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 1423
+E +++ D+D + +KQ +++ ++LE+ L +A ++ K +E
Sbjct: 4240 MEKERDNMDQSIKSLDEDLKMMKLQKQVIEEEKNKLEQMKFELQREADEIRKIKEETQNE 4299
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDNWVPF 1603
L++ KE++DL + E T + ++ + D + ++ M+D +
Sbjct: 4300 RQSLEKMTKALIKEREDL-VHLAEYTKREKEML----DEMQVANKSSMADLQREKRIL-- 4352
Query: 1604 EDLVQGFSRKTSPLDITKTCDAVDISEDSTTNIQVD 1711
E++ + S++T DI + + ED +Q +
Sbjct: 4353 EEMRENISKQTE--DIENEKEKSKLREDELKKLQTE 4386
Score = 72.8 bits (177), Expect = 6e-10
Identities = 117/569 (20%), Positives = 233/569 (40%), Gaps = 66/569 (11%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNI----LEAAKQALEYKVADLEAAK 169
Q+ + + + + T+ L DE +++ + N+ ++ K +LE ADL+
Sbjct: 13954 QSEKESIEEEKKTLKQLKDENESKRTQLDNTIEKMNMDKLSIQREKDSLEEIKADLQRKA 14013
Query: 170 TTLNDELERKKDDNNAIIKKAL--------DKRISDLKADAPQRDQ--EDDMNALIXXXX 319
L++E+ + + I + A ++ + ++AD ++ + E D+ L
Sbjct: 14014 EKLDEEMRKAVQITSQISQDAKILDDDREKEEELRSMRADIERQAKILESDVQLLQTEKE 14073
Query: 320 XXXXXXXXXXXIVSNLEV----NILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVS 487
+ +LE N L L +EL+KEK +I D+ + + V+
Sbjct: 14074 ILEKSKTENDLLREDLEKQRKRNDLTL-QELRKEKMALEQMITDITKEK-------DAVA 14125
Query: 488 HLESKSRSLKEHFLREEEDEVLE--RSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
L+++ SLK+H L+ +E E+ E + +L + +R+ K++ +
Sbjct: 14126 SLQNEV-SLKQHELKNKETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR 14184
Query: 662 AEKQGLEKTVLERRASNLDTM---------------DAIHE-EELRKEKVDKSALTENGE 793
+ + ++ + E R D + DA+ + +EL K D E+ E
Sbjct: 14185 NDLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVE 14244
Query: 794 GCEAEKQGPEKTVLDLEPTIPSLN---DALQRDLDRVMAEKQALEKRCSDLEA------- 943
E K ++ + + SLN + ++++ A+ ++LE+ +DL A
Sbjct: 14245 KEREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKT 14304
Query: 944 -----KNASLTDNQEGHEAEIERKL-----EASNLTHNDELHKEKDDKESIMNDLDH--- 1084
K ++ D ++ E E++ L E L + E K + + IM D
Sbjct: 14305 LVQTEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEV 14364
Query: 1085 ------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLN-ERDGLEAVKQGLEKR 1243
+K+ER VLE + S++ LN ++Q++ ++ E L ERD +E K+ +E
Sbjct: 14365 EDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE-- 14422
Query: 1244 VLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSE 1423
+EKQ++++ +EL K+L +++ + E
Sbjct: 14423 -----------------------SEKQSIERERAEL-----------KRLKEEVEVQ-HE 14447
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKL 1510
T LQ+D N KEK+ LE T ++
Sbjct: 14448 RTLLQQDKNMIQKEKEHLEGEKARTTEEI 14476
Score = 71.6 bits (174), Expect = 1e-09
Identities = 107/531 (20%), Positives = 221/531 (41%), Gaps = 28/531 (5%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
++ ++ + E T + EL N + K+ I ++R+ +E K L+ + D E + + ++
Sbjct: 2779 IKQEMDELEQTRLNVVKELENNELQKQIIEDERDKIEQIKAELQKEAKDTEKQRQDIEND 2838
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++++ +IK +K+ + D + +
Sbjct: 2839 ---RRNNEEMVIKLQNEKKDIETSTDR-----------------------------IRDE 2866
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLR-EEED 544
E N+ +L + L+ ++D L K+ + + ++ LES++R + ++E
Sbjct: 2867 EANLRVLKQRLESDRD---TLEKERFDLKKTNTEMKDLEKQLESQNRQHEIQLAEIQKER 2923
Query: 545 EVLERSASNLAIMKAIREEE---LRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNL 715
E+LE+ L+ K E+E KEK S E E ++E++G+ KT R
Sbjct: 2924 EILEQLKLTLSKQKEDLEKERDCFEKEKADISLREELQE--QSEREGIGKT----RVRIK 2977
Query: 716 DTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRV 895
MD EL++ +++ EN E +KQ ++ + D++
Sbjct: 2978 KEMD-----ELKQTRLNVVKELENNE---LQKQ------------------IIEDERDKI 3011
Query: 896 MAEKQALEKRCSDLEAKNASLTDNQEGHEAEI------ERKLEASNLTHNDELHKEKDDK 1057
K L+K D E + + ++ +E + ++ +E S DE + K
Sbjct: 3012 EQIKAELQKEAEDTEKQRRDIEKDRRNNEEMVIKLQNEKKDIETSTDRIRDEEANLEVQK 3071
Query: 1058 ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLE 1237
+ + +D D ++ ER LE ++M L ++++Q ER+ LE +K L
Sbjct: 3072 QRLESDRDTLEKERFDLEKTKTEMGNLKKQLESQIRQHEIQLVEIQKEREILEQLKINLS 3131
Query: 1238 KRVLDLEATIHDIEMKTG----KDDDYNEAEKQ-------TLKKRISELEEAISIL---- 1372
K+ DLE E + +D ++E++ +K+ + ELE+ L
Sbjct: 3132 KQKEDLEKERDCFEKEKADISLSEDLKEQSEREGIDNTRTRIKQEMDELEKTRQNLAKEQ 3191
Query: 1373 --TDKAKKLLKDINIWLSEV-TELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+ KK+++D + ++ EL+++ K E Q+ + + E +KL+K
Sbjct: 3192 ENNELQKKIIEDERDKIEQIKAELKKEAEKTKLELQNERQNLEEAGTKLKK 3242
Score = 71.6 bits (174), Expect = 1e-09
Identities = 111/536 (20%), Positives = 234/536 (43%), Gaps = 60/536 (11%)
Frame = +2
Query: 86 KCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LERK-KDDNNAIIKKALDKRISD 253
K + NDRN++E + LE ++L + + DE L++K K+ N K +K I +
Sbjct: 10455 KKLNNDRNMIEKERNDLEKMKSELMTQRQQMEDERSELDQKIKEANTEKDKIEKNKEIVE 10514
Query: 254 LKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKE----KDDK 421
+ A +Q +D +++ E + E+++ K+++
Sbjct: 10515 -RLMAEVEEQRNDFKLKKEELALERQNIVDEKYLLAQCETELQNKSEQIRNMEEAVKNER 10573
Query: 422 TALIKDLVAAEPGKRTVNEIVSHLESKSRSL----------------KEHFLREEEDEV- 550
L + + K+ + I+ + L K+ L +E +E+
Sbjct: 10574 ETLKETEAHLQRDKKEIKSIIEETSRQKEDLEKISTGMNVQKQELKNKKDTLEQEREEIN 10633
Query: 551 ------LERSASNLAIMKAIREEELRKEK---DGKSALVE-NGEGCEAE-KQGLEKTVLE 697
+R A ++ +EE+L +K + + L E NG+ E + K LE +
Sbjct: 10634 HKWTQFQQRIDEFDAQVRKQKEEDLTNQKKMEEERKCLEEVNGKIIEMKTKAELEHHEIN 10693
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPT-IPSLNDAL 874
++ L T+ +E++ KEK A+T + E E K+ L E T + L
Sbjct: 10694 QKIEELQTL----QEQIMKEKEKAEAMTIKLK-MEREDLDQIKSELVREKTEVDHEQKKL 10748
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
D+ + EK+ LEK S++ + + E +E++ K++ ++L +D + K K+
Sbjct: 10749 NDDIKMIEQEKEDLEKMKSEIMTQKQEM----EKERSELDNKIQQTDLEKHD-IEKSKEI 10803
Query: 1055 KESIMNDLDHVKAERQVLES-------KVSDMETTY----STLNNELQQKMDDNEAFLNE 1201
E +M +++ + E Q+ + K++D + S L NE ++ + NE E
Sbjct: 10804 VEKLMFEVEEQRHEIQLQKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEVIKKE 10863
Query: 1202 RDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDD------DYNEAEKQTLKKR--ISELEE 1357
R+ L+ ++ LEK ++++ E + K+D D E + +K+R + + +E
Sbjct: 10864 RETLKEMEAHLEKEKEEMKSITE--ETRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKE 10921
Query: 1358 AISILTDKAKKLLKDINIWLSEVTE----LQEDLNKESKEKQDLEKRVLELTSKLE 1513
I+ + ++ + + + +S+ E Q+++ +E K ++ + R++E+ +K E
Sbjct: 10922 DINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKEERKSLEETKARIIEMKTKAE 10977
Score = 71.6 bits (174), Expect = 1e-09
Identities = 109/563 (19%), Positives = 243/563 (43%), Gaps = 50/563 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE---LER 196
D E+ L++E +D+ K + +N+L +K + +LE T + E +E+
Sbjct: 14186 DLESMKTLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEK 14245
Query: 197 KKDD----NNAIIK-----KALDKRISDLKAD-APQRDQEDDMNALIXXXXXXXXXXXXX 346
++++ N IIK ++L+ I K + A +R Q + + L
Sbjct: 14246 EREEIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTL 14305
Query: 347 XXIVSNLEVNI------LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSR 508
+ + + L LQK+K++ L ++ + AE K V L+ + +
Sbjct: 14306 VQTEKQMAIEDTEKKTEVELQMNLQKQKNELEEL-RNTIEAE--KHQVENRKIMLDKQQK 14362
Query: 509 SLKEHF-LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENG----EGC----E 661
+++ + + E +VLE+ S L + + E++++E++ L+E E C E
Sbjct: 14363 EVEDIMTVIKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIE 14422
Query: 662 AEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDL 841
+EKQ +E+ E + + ++ HE L ++ DK+ + + E E EK + + +L
Sbjct: 14423 SEKQSIERERAELKRLK-EEVEVQHERTLLQQ--DKNMIQKEKEHLEGEKARTTEEIHNL 14479
Query: 842 EPTIPSLNDALQRDLDRVMAEKQALE--------------KRCSDL---EAKNASLTDNQ 970
+ I + L + A++Q E K+ D+ E TD
Sbjct: 14480 KEEIKRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDAS 14539
Query: 971 EGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVL----ESKVSDMETT 1138
+ + + + +A T DE+ K + ++ + + A++ ++ ++ S+++
Sbjct: 14540 QKFQLKTTSR-DAETQTSLDEITKTDERRQRALEETVATTAKQPIVIKLEDTLTSEVQEM 14598
Query: 1139 YSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAE 1318
LNNE+++ E+D L+ K ++ ++ + E + + + +++
Sbjct: 14599 RDHLNNEIKELARMKTIMKMEKDQLKQAKSDIQTQMEEFERNMEEAMEEKSRNE------ 14652
Query: 1319 KQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLEL 1498
+ L + + E+ + L K K++ + +L ++ +L+ + K+K+++E +L+L
Sbjct: 14653 -EKLLQLTHDKEDLSNTLDKKNKEIENNTETFLKKIAQLETTIVLMKKDKENIENELLQL 14711
Query: 1499 TS-KLEKCICGARDGLSTIKEAW 1564
+ E+ I D ST KE +
Sbjct: 14712 KQIEQEREIQRKADVTSTEKEMY 14734
Score = 70.9 bits (172), Expect = 2e-09
Identities = 125/570 (21%), Positives = 246/570 (43%), Gaps = 69/570 (12%)
Frame = +2
Query: 11 ENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDEL 190
++++ + I L EL EK+ I+ DR+ L+ + ++L+ +T +ND +
Sbjct: 4167 QDELDQLKTEIQNLQQELEKEKE---IIMKDRS-------ELDLRQSELDKQQTNMNDII 4216
Query: 191 ERKKDDNNAIIKKALDKRISDLKADAPQRDQE-DDMNALIXXXXXXXXXXXXXXXIVSNL 367
E K++ +K LDK +++ + ++E D+M+ I ++
Sbjct: 4217 ETMKNE-----RKLLDKDKEEMEEQKQEMEKERDNMDQSIKSLDEDLKMMKLQKQVIEEE 4271
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS----LKEHFLRE 535
+ + + ELQ+E D+ I+ + +R E ++ K R L E+ RE
Sbjct: 4272 KNKLEQMKFELQREADE----IRKIKEETQNERQSLEKMTKALIKEREDLVHLAEYTKRE 4327
Query: 536 EE--DEVLERSASNLA-------IMKAIRE------EELRKEKDGKSALVENGEG---CE 661
+E DE+ + S++A I++ +RE E++ EK+ KS L E+ E
Sbjct: 4328 KEMLDEMQVANKSSMADLQREKRILEEMRENISKQTEDIENEKE-KSKLREDELKKLQTE 4386
Query: 662 AEKQ----GLEKTVLERRASNLDTMDAIHEEELRKEKVD-----KSALTENGEGCEAEKQ 814
+KQ +EKT +E + + EL+K+ D K LTE E E +
Sbjct: 4387 VQKQQSEIDMEKTNIESERAVMIREKQNMMTELKKKSEDVEIQMKEILTEK-ELLENDSN 4445
Query: 815 GPEKTVLDLEPTIPSL---NDALQRDLDRVMAEKQALEKRCSDLE--AKNASLTDNQEGH 979
+K + DL+ + S+ +++L+ D + EK+ L++ +DL+ A + H
Sbjct: 4446 LLKKDMEDLKQKLMSIERDSESLKLDREAFGNEKEVLKQMKTDLQIQADEIEKIKLETQH 4505
Query: 980 EAEIERKLEASNLTHNDELHK---EKDDKESIMNDLDH--------VKAERQVLESKVSD 1126
+ + + A DE++ E + K+ ++N++D +++++ +LE + +
Sbjct: 4506 DRQRVEEKTAQIQKDRDEINNLIVETNRKDMVLNEMDRDIEEKIKSIQSDKDMLEKERHN 4565
Query: 1127 METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDY 1306
+E T S L + E ER +E +K+ + + + +++ H E K D+
Sbjct: 4566 LEKTRSELARAKENLETQREI---ERKDIEKMKKNISREMHEIK---HQEEQMKQKQDEL 4619
Query: 1307 N-------------EAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLS--------E 1423
+ E EK+ + K S+L+ S L DK + + DI + +
Sbjct: 4620 DQLKTEIQNLQQELEKEKEIIMKARSQLDLRQSEL-DKQQTNMNDIMETMKNERKQLDKD 4678
Query: 1424 VTELQEDLNKESKEKQDLEKRVLELTSKLE 1513
E +E + KEK D ++ L L+
Sbjct: 4679 KEETEEQKQEMEKEKHDFDQSRKSLDEDLK 4708
Score = 70.9 bits (172), Expect = 2e-09
Identities = 120/625 (19%), Positives = 268/625 (42%), Gaps = 75/625 (12%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNE----KDDKKCIVNDR-NILEAAKQALEYKVADLEAAKT 172
L+ ++ +F+A ++ ++ L + K+D+K + + N++E +A + +++ K
Sbjct: 11208 LQQRIDEFDAQVSKQKEQDLPKEKGMKEDRKSLEETKANVIEMKTKA---EPEEIKKEKE 11264
Query: 173 TLNDELERKKDDNNAII---KKALDKRISDLKADAPQRDQE----DDMNALIXXXXXXXX 331
N+E E ++++ I+ +K L + S+L+ + D E +D +I
Sbjct: 11265 KENEEEEEEEEEIRVIVETERKELYQIKSELERVRSEIDHEQKKLNDYMKMIEQEKED-- 11322
Query: 332 XXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRS 511
+ ++ I+ +++++E+ + I+ + H KS+
Sbjct: 11323 --------LEKMKSEIMKQRQQMEEERSELDNKIQQ-----------TNLEKHDIEKSKE 11363
Query: 512 LKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV 691
+ E + E E++ ++ + K + E +K D ++ LV+N + E + ++K V
Sbjct: 11364 IVEKLMVEVEEQ-----RKDIQLQKEELDIERQKIADEQNLLVQNKAKLQNENERIKK-V 11417
Query: 692 LERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
E +T+ + E L+KEK + ++ E + + + + + + + + + D
Sbjct: 11418 DEEIKKERETLREM-EIHLKKEKEELRSIIEETQRRKEDLEKMSTDINEQKLHLKNQRDL 11476
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERK---------LEASNLTH 1024
L+++ + + E L++R + +A+ + ++ E E ERK +E
Sbjct: 11477 LEQEREEINHEMTQLQQRIDEFDAQVSKQREDLTKQEMEEERKSLEETKARIIEMKTKAE 11536
Query: 1025 NDELHKEKDDK-ESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNE 1201
E+ +EK+++ E M + V+ ER+ L S+++ S +++E ++ DD + E
Sbjct: 11537 LQEIMQEKEEEDEEEMRVI--VEMEREELNQIKSELKRVRSEIDHEQKKLNDDKKIIEQE 11594
Query: 1202 RDGLEAVK-------QGLEKRVLDLEATI-------HDIE-------------------M 1282
++ LE +K Q +E+ +L+ I HDIE +
Sbjct: 11595 KEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDI 11654
Query: 1283 KTGKDD---------------DYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL 1417
+ K++ N+A+ Q +RI E++E I K K+ LK++ L
Sbjct: 11655 RLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIK----KEKETLKEMEAHL 11710
Query: 1418 SEVTELQEDLNKES--KEKQDLEKRVLELTSKLEKCICGARDGLSTIKEAWMSDCMVPDN 1591
+ E + +E+ ++K+DLEK ++ +K + + RD L +E +
Sbjct: 11711 RKEKEEMRSVIEETQRRKKEDLEKMSTDV-NKQNQDLMNQRDLLKQEREE------INHK 11763
Query: 1592 WVPFEDLVQGFSRKTSPL---DITK 1657
W + + F + S D+TK
Sbjct: 11764 WTQLQQRIDEFDAQVSKQKEEDLTK 11788
Score = 69.3 bits (168), Expect = 7e-09
Identities = 116/533 (21%), Positives = 226/533 (42%), Gaps = 17/533 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDE 187
L+ + ++ + +ND + K+++K + D+ +E KQ +E + +++ ++ +L+++
Sbjct: 5738 LDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDED 5797
Query: 188 LERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
++ K + K+ ++ + L+ + ++E D + I N
Sbjct: 5798 QKKMK-----LQKQMFEEEKNKLEQMKIELEREADEISKIKEE-------------TQNK 5839
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
+ + EEL +EK+ L +D + K+ ++E+ ES L + E
Sbjct: 5840 RQRLEKMTEELIREKESLAHLAED---TKTEKKILDEMKVANESSMADL------QREKS 5890
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSAL--VENGEGCEAEKQGLEKTVLERRASNLDT 721
+LE N++ +K + E K K + L ++ + K +EKT +E + +
Sbjct: 5891 ILEEMRENISKLKEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIR 5950
Query: 722 MDAIHEEELRKEKVD-----KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDL 886
EL+K+ D K LTE E + D+E L D L+RD
Sbjct: 5951 EKQNMMTELKKKSEDVEIQMKEILTEK----ELLHNDRKLLTRDVENLQQKLID-LERDS 6005
Query: 887 DRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER-KLEASNLTHNDE-----LHKEK 1048
R+ +++A E ++ EA TD Q + EIE+ KLE + E + KE+
Sbjct: 6006 KRLKLDREAFE---NEKEAMKQMKTDLQIQAD-EIEKIKLETQHDRQRVEEMAAQIQKER 6061
Query: 1049 DDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQ 1228
D I N ++ + VL K D+E ++ ++ + R L VK+
Sbjct: 6062 D---KINNLIEETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKERHNLEKTRSELYKVKE 6118
Query: 1229 GLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDIN 1408
LEK+ E T+ +I+ + + NE + + + I EE ++ D+ +L
Sbjct: 6119 DLEKQ---KENTLAEIQKEREDVEKMNENITREMHE-IKHQEEQMNQKQDELDQL----- 6169
Query: 1409 IWLSEVTELQEDLNKES----KEKQDLEKRVLELTSKLEKCICGARDGLSTIK 1555
+E+ LQ++L KE K++ + R S+L+K D + T+K
Sbjct: 6170 --KTEIQNLQQELEKEKEIIMKDRSQFDLR----QSELDKQQTNMNDIMETMK 6216
Score = 68.9 bits (167), Expect = 9e-09
Identities = 117/544 (21%), Positives = 231/544 (42%), Gaps = 39/544 (7%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDD--------KKCIVNDRNILEAAKQALEYKVADL 157
Q AD E + EL KD+ +K V+ + + +++ E +L
Sbjct: 1711 QTATQTTADMELQLELQKQELEQTKDEMERTKLEVQKGWVDLQTQIAESREKEEMVRIEL 1770
Query: 158 EAAKTTLN---DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXX 328
E A+ LN ++E +K A +K L K +L+A ++ ED+ AL
Sbjct: 1771 EKARDVLNRIRQDVETEKQTMEADLKFTLAKEFENLEAQ--RKMMEDEKRALENMKYELQ 1828
Query: 329 XXXXXXXXIVSNLEVNILILH----------EELQKEKDDKTAL-------IKDLVAAEP 457
N+ + EEL+K++ D L IKDL
Sbjct: 1829 RESGYIERSKHNMHDERQNMENWAEKLKQEWEELEKKRHDMQQLQTERSREIKDL----E 1884
Query: 458 GKRTVNEI-VSHLESKSRSLKE-HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKS 631
R +NE+ ++ +++KS L++ L ++ + +E S + I RE +L++ + +
Sbjct: 1885 NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKI----REYDLQQMQTDLN 1940
Query: 632 ALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENG-EGCEAE 808
+ E Q ++ V ++ + D I E+ K+ D T+N + + E
Sbjct: 1941 RQ-------QKEMQDIQNAVFMEKSELKKSQDEIAEQ--LKQVGDMMQFTQNEKDNLDRE 1991
Query: 809 KQGPEKTVLDLEPTIPSLNDALQRDLDRV-MAEKQALEKRCSDLEAKNASLTDNQEGHEA 985
+ + L +E + L L R+L+ + + +K+ L ++ + + + + D Q+ +
Sbjct: 1992 RAAIIEQKLQMERDMTHL---LNRELESLKLVKKEVLNEKRLLEDCRISLMRDMQDLEQM 2048
Query: 986 EI--ERKLEASNLTHNDELHKEKDDKESIMNDL--DHVKAERQVLESKVSDMETTYSTLN 1153
+I ER+ E L + +EKD ES++ L D K L K +E L
Sbjct: 2049 KINLEREKEEMQL-QRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEK-QKLEDAAVELQ 2106
Query: 1154 NELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLK 1333
E + M+ E +R+ ++ ++ G+EK+ E T D++ K+ E ++Q ++
Sbjct: 2107 KERDEIMNIAEETKRKREDVDKIRVGIEKQ----EITFKDLKADLQKEAAIVENQRQAVQ 2162
Query: 1334 K---RISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTS 1504
K + ++E I +L+++I + E+Q +++KE +E + + + TS
Sbjct: 2163 KDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKALDEMQMEVDKERQEVESKRDELEQETS 2222
Query: 1505 KLEK 1516
KL +
Sbjct: 2223 KLRE 2226
Score = 68.9 bits (167), Expect = 9e-09
Identities = 104/526 (19%), Positives = 213/526 (40%), Gaps = 32/526 (6%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKC----IVNDRNILEAAKQALEYKVADL------ 157
L+ V D L ++LL E++ K I ++++L KQ + + D+
Sbjct: 3289 LKKTVTDIAGAKEDLENQLLEEREKNKVKQAEIQAEKDMLYLLKQGISEQQVDIVNKTEQ 3348
Query: 158 ----EAAKTTLNDELERKKDDNNAIIKKALDK--RISDLKADAPQRDQEDDMNALIXXXX 319
E L + R++D+ A K +++ R+ K + + +E +
Sbjct: 3349 LRLREVELEQLQALIYRQQDEIEANRKAIINEKYRLEGQKTEIDRLQREVNQMMEYASKD 3408
Query: 320 XXXXXXXXXXXIVSNLEVNILILHEELQKEK---DDKTALIKDLVAAEPGKRTVNEIVSH 490
I +++I EL KE+ +++T ++ KRT E+
Sbjct: 3409 RANLEKEKSEMIAQKHQMDI-----ELNKERGLIEERTQMLNTYEKEMDQKRTALEV--- 3460
Query: 491 LESKSRSLKEHFLREEEDEV------LERSASNLAIMKAIREEELRKEKDGKSALVENGE 652
E K + ++EE++++ L+R A ++ +K E+ R E+ + EN
Sbjct: 3461 -EMKELKYHKQAIQEEKNKLQQMKIELQREADDIKKLK----EKTRNERQSLEKMAEN-- 3513
Query: 653 GCEAEKQGLEKTVLERRASNLDTMDAIHEE---ELRKEKVDKSALTEN----GEGCEAEK 811
E EK L + + + D M +HE +++KEK + + E+ E ++EK
Sbjct: 3514 -LEKEKDDLAHLAEDTKRKD-DEMKVLHESALADIQKEKCNLEQMRESMFKQNEMIDSEK 3571
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
K ++ E + + + R + +K +E + + KN L
Sbjct: 3572 ----KKMILREDKLQQMQAEINRQQTEMDTKKSIIENERAAMTKKNQDLMT--------- 3618
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQK 1171
EL K+ +D E M + V E+++LES ++ L +L
Sbjct: 3619 -------------ELTKQSEDVEIQMKE---VLTEKELLESDRKLLKKDVENLQQKLLII 3662
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISEL 1351
D+E+ +R+ LE K+ L++ DL+ +IE K + + + + +I +
Sbjct: 3663 ESDSESLKQDRELLENEKEVLKQMKTDLQGEAEEIE-KIKLETQHERQRVEEMTAQIQKD 3721
Query: 1352 EEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
E + + D + + DI ++ + Q++L++ E Q+L++ +
Sbjct: 3722 REYLQKMNDNITREIHDIKYQEKQMKQKQDELDQLKTEIQNLQQEL 3767
Score = 68.6 bits (166), Expect = 1e-08
Identities = 121/564 (21%), Positives = 227/564 (40%), Gaps = 64/564 (11%)
Frame = +2
Query: 17 KVADFEATIATLNDELLN-EKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELE 193
K+ E I T E+ E+ +K + +N+ E Q L+ + +L KT + ++E
Sbjct: 13340 KIKQIEGEIKTKQIEMACLEELKQKELDEQKNMRECENQELQMRREELAKMKTEI--DIE 13397
Query: 194 RKKDDNNAIIKKALDKRISDLKADAP--QRDQEDDMNALIXXXXXXXXXXXXXXXIVSNL 367
R D ++K +K +L+ P Q+ + + ++A + +
Sbjct: 13398 R---DEIQKLRKQYEKEKCELEQIKPDLQKREPEKIDAEVQH---------------DEI 13439
Query: 368 EVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDE 547
I L EE ++ + K L L AE + + LE K +++ + E+++
Sbjct: 13440 HGGIDSLKEEREEIEKMKADLQNKLREAENMRDIMKREKDELEKKEAEIEQMAVETEDND 13499
Query: 548 VLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKT--VLERRASNLDT 721
+ + ++AI L+ K K+ L + E EK LE +LER + L+
Sbjct: 13500 SDKNLQDEMMKIEAI----LKVTKKQKNYLEQMNENLTREKTELETNCQMLEREKTELNK 13555
Query: 722 ---------MDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDAL 874
M + E E ++ +++ + E E E K+ E+ V ++E I L
Sbjct: 13556 KVKETEEFHMSKMEEREAERKTIER-VMDEMAEEHEKIKKEREELV-NMEEEIKKQRRVL 13613
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTD---------------NQEGHEAEIERKLEA 1009
+ ++ + +K L+ S+L + L D Q+ + +I ++
Sbjct: 13614 EESMNEMTKKKSELQHERSELYKQKQQLEDMIASESKRDVDTERSRQDKEDEQILKRERE 13673
Query: 1010 SNLTHNDELHKEKDD----KESIMNDLDHV----------KAERQVLESKVSDMETTYST 1147
D+L KEK+D KE I + +H+ K E + K+ M+T
Sbjct: 13674 EIADMKDQLLKEKEDVETTKERINREKEHIEKMQSQLNDQKEEMDLENQKLLYMKTEIQV 13733
Query: 1148 LNNELQQKMDDNEAFLNERDGLEAV-----KQGLEKRVL-------------DLEATIHD 1273
N L++ M D + ER+ + A+ K+ ++ +L +++ D
Sbjct: 13734 KTNALEKMMQDLQ---KERENVNALVIQHQKEREQRDILIEENKRKEKHAEAEIQRQFED 13790
Query: 1274 IE-MKTGKDDDYNEAEKQT--LKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQED 1444
IE +K + N+ +K LK R ELE I KK K+ ++ E+Q +
Sbjct: 13791 IESVKVRLVTESNQIDKMNSELKTRSEELENLI-------KKQQKEFE---TKENEMQRE 13840
Query: 1445 LNKESKEKQDLEKRVLELTSKLEK 1516
K +LE++ EL +K+EK
Sbjct: 13841 RKALEKMNAELERKSTELKNKIEK 13864
Score = 65.9 bits (159), Expect = 7e-08
Identities = 92/447 (20%), Positives = 194/447 (43%), Gaps = 36/447 (8%)
Frame = +2
Query: 461 KRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDG-KSAL 637
+ T E++ LE + R+ K R L + +++K KD K
Sbjct: 80 RMTEPELIQELEWRQRNTKHTQTETGSPPSSPREKRRLEDKSGL-SSDIQKRKDSLKRRR 138
Query: 638 VENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQG 817
E E ++ E T ER + +D M ++++++++ + + +T EK
Sbjct: 139 FETMRAIEQIEKLWEGTKQER--TEIDNM----KQKIQRQQDEITRMT-------TEKGQ 185
Query: 818 PEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
E+T+ ++ I + + + R+ + V E++ +E+ SDL+A+ +SL Q+ E ER
Sbjct: 186 LERTITHMKAEIDHIRERMDRNKEEVNRERERVEQMRSDLQAEQSSL--QQKRDEIMTER 243
Query: 998 K----LEASNLTHNDELHKEKDDKESIMNDLDHVKAERQV----LESKVSD--------- 1126
+ + L +EL ++ + M ++ +K+ QV +E K+ +
Sbjct: 244 QNLEMIRYETLRQQEELESNRESTKHEMERMEQMKSAIQVQINEIEMKIGETQKAKDLME 303
Query: 1127 -METTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDD 1303
M+ NEL++K +D + +RD E +K L++ +++E H+ E + +
Sbjct: 304 QMKAEIEDEKNELEKKKEDIK---RQRDQFEQIKLDLQQVKMEMEQRWHETEKEGLEQRA 360
Query: 1304 YNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEV--TELQEDLNKESK----- 1462
+ EK+ LK E++ + ++ ++ K + +S++ L+E+ E+K
Sbjct: 361 VIQREKEQLKYLQDEIQR-VREEVERNREFSKQEHARISQLRAQALEENNLIENKWHDIL 419
Query: 1463 -EKQDLEKRVLELTSKLEKCICGARDGLSTIKEAW----MSDCMVPDNWVPFEDLVQGFS 1627
+++DLE+ E+ E+ + +K+ W + + + + E V
Sbjct: 420 RKEKDLEEMKHEIERGREELVMNG----ELVKKEWEKIEQAKVDIQSHMISMEGRVDEIK 475
Query: 1628 RKTSPLDITKT-----CDAVDISEDST 1693
R+T L KT DA++ +D T
Sbjct: 476 RETERLKHIKTEMQRDKDALEKQKDDT 502
Score = 65.1 bits (157), Expect = 1e-07
Identities = 118/608 (19%), Positives = 236/608 (38%), Gaps = 108/608 (17%)
Frame = +2
Query: 17 KVADFEATIATLNDELLNEKDDKKCIVN--------DRNILEAAKQALEYKVADLEAAKT 172
++ D E + LN+ LN+ K ++ ++ +E K ++ + DL+ +T
Sbjct: 1879 EIKDLE-NLRELNELTLNQIKTKSDVLEKISELNSQQKDEIENEKSKIKIREYDLQQMQT 1937
Query: 173 TLNDELERKKDDNNAII--KKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXX 346
LN + + +D NA+ K L K ++ A Q Q DM
Sbjct: 1938 DLNRQQKEMQDIQNAVFMEKSELKKSQDEI---AEQLKQVGDMMQFTQNEK--------- 1985
Query: 347 XXIVSNLE-VNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
NL+ I+ ++LQ E+D L ++L + + K+ V LE SL
Sbjct: 1986 ----DNLDRERAAIIEQKLQMERDMTHLLNRELESLKLVKKEVLNEKRLLEDCRISLMRD 2041
Query: 524 FLREEEDEV-LERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE----AEKQGLEKT 688
E+ ++ LER + + + EE K + L E+ E AEKQ LE
Sbjct: 2042 MQDLEQMKINLEREKEEMQLQRQSIAEEKDKLESVLQTLAEDTEKLRIDTLAEKQKLEDA 2101
Query: 689 VLERRASNLDTMDAIHEEELRKEKVDK----------------------SALTENGEGC- 799
+E + + M+ E + ++E VDK +A+ EN
Sbjct: 2102 AVELQKERDEIMNIAEETKRKREDVDKIRVGIEKQEITFKDLKADLQKEAAIVENQRQAV 2161
Query: 800 --------------EAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 937
+ E+Q ++ V ++E +L D +Q ++D+ E+Q +E + +L
Sbjct: 2162 QKDIQNVKDMEVQIQKERQYMDRLVEEIEKRTKAL-DEMQMEVDK---ERQEVESKRDEL 2217
Query: 938 EAKNASLTDNQEGHEAEIER----KLEASNLTHNDELHKEKDDKESIMNDLD-------- 1081
E + + L ++++ + E+ + E + N EL E KE + +L+
Sbjct: 2218 EQETSKLREDEDEFSRQKEKNNIIQAEIQKESDNLELQSENISKERTIFELEKEHLGLRE 2277
Query: 1082 -------------------------HVKAERQVLESKVSDMETTYSTLNNELQQKMDDNE 1186
++A++ K ++T L+++ + E
Sbjct: 2278 NEAEYKQKQIDELQNKLRMEKVQVEQMQADKDQQRKKAEYVKTARGRETTALEEQRQEME 2337
Query: 1187 AFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEA----------EKQTLKK 1336
+ E + +E K+ + ++ E+ + +EM+ Y E ++Q +K
Sbjct: 2338 SLREEYENVEKQKKHVNEQKELFESRMKSLEMENEAMKKYKEKLDKEYEDLQFQRQLFEK 2397
Query: 1337 RISELEEAISILTDKAKKLLKDINIWLSEV------TELQEDLNKESK--EKQDLEKRVL 1492
I ++ + I + ++ K++ I V E Q+ + ++SK E ++ K++
Sbjct: 2398 EIQQMRTELQIEAENIERKKKELEIQKPAVYTETYMLETQKPVVEKSKTDELDEVRKKIN 2457
Query: 1493 ELTSKLEK 1516
S++EK
Sbjct: 2458 ADLSEVEK 2465
Score = 63.9 bits (154), Expect = 3e-07
Identities = 103/563 (18%), Positives = 240/563 (42%), Gaps = 74/563 (13%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 226
L++++ +K I + I+E +E + D++ K L+ E ++ D+ N +++
Sbjct: 11344 LDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQRKDIQLQKEELDIERQKIADEQNLLVQN 11403
Query: 227 -----------KALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIV 358
K +D+ I + + + +++++ ++I +
Sbjct: 11404 KAKLQNENERIKKVDEEIKKERETLREMEIHLKKEKEELRSIIEETQRRKEDLEKMSTDI 11463
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 538
+ ++++ + L++E+++ + L ++ ++E + + + L + + EE
Sbjct: 11464 NEQKLHLKNQRDLLEQEREEINHEMTQL------QQRIDEFDAQVSKQREDLTKQEM-EE 11516
Query: 539 EDEVLERSASNLAIMKAIRE-EELRKEKDGKS-----ALVENGEGCEAEKQGLEKTVLER 700
E + LE + + + MK E +E+ +EK+ + +VE E E+ K+ L+R
Sbjct: 11517 ERKSLEETKARIIEMKTKAELQEIMQEKEEEDEEEMRVIVE----MEREELNQIKSELKR 11572
Query: 701 RASNLDTMDAIHEEE--------LRKEKVD----KSALTENGEGCEAEKQGPEKTV--LD 838
S +D HE++ + +EK D KS + + E E+ + + D
Sbjct: 11573 VRSEID-----HEQKKLNDDKKIIEQEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTD 11627
Query: 839 LEP-TIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1015
LE I + + +Q+ + +V +++ + + +L+ + + D Q G + + KL+ N
Sbjct: 11628 LERHDIENSKEIVQKLMVKVEEQRKDIRLQKEELDIERQKIADEQ-GLVVQNKAKLQNEN 11686
Query: 1016 LTHNDELHKEKDDKESIMNDLDHVKAERQVLES--------KVSDMETTYSTLNNELQQK 1171
+ + K +KE++ H++ E++ + S K D+E + +N + Q
Sbjct: 11687 ERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRKKEDLEKMSTDVNKQNQDL 11746
Query: 1172 MDDNEAFLNERDGLEAVKQGLEKRVLDLEATI-----HDIEMKTGKDDDYNEAEKQTL-- 1330
M+ + ER+ + L++R+ + +A + D+ + +++ E+ +
Sbjct: 11747 MNQRDLLKQEREEINHKWTQLQQRIDEFDAQVSKQKEEDLTKQKKMEEERKSLEETKIKI 11806
Query: 1331 -------------KKRISELEEAISILTDKAKKLLKDINIWL----SEVTELQEDLNKES 1459
K++ E EE + + K+ L I L SE+ Q+ LN +
Sbjct: 11807 IEMKTKTEPEKIKKEKEKEEEEVMRAKVEMKKEELDQIKSQLERVRSEIDHEQKKLNDDK 11866
Query: 1460 K----EKQDLEKRVLELTSKLEK 1516
K EK+DLEK E+ + ++
Sbjct: 11867 KMIEQEKEDLEKMKSEIMKQRQQ 11889
Score = 63.9 bits (154), Expect = 3e-07
Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 16/514 (3%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALE-YKVADLEAA------ 166
+EN F IA L ++ K DK+ I N+ L+ +Q E + AD+ +
Sbjct: 14676 IENNTETFLKKIAQLETTIVLMKKDKENIENELLQLKQIEQEREIQRKADVTSTEKEMYT 14735
Query: 167 -KTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXX 343
K T ELE K+ IK D + D+ + D E + L
Sbjct: 14736 EKVTYKTELEDSKEK----IKPDRDSTLELTDTDSAKTDGEREAQTL-----------ET 14780
Query: 344 XXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEH 523
V L + EEL E ++K +I +L A+ + + L+ + RS +E
Sbjct: 14781 KVQDVLQLTDDTTQDQEELHDEMENKMKIILELNKAK-------KDLQKLKEECRSAEEE 14833
Query: 524 FLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLE-KTVLER 700
+ E LER ++L E+++ E + +++ + E Q +E K ++
Sbjct: 14834 --KSVIMESLERRRNSL--------EKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQT 14883
Query: 701 RASNLDTMDAIHEEELRKEKVDKSA-LTENGEGCEAEKQGPEKTVLDLEPTIPS-LNDAL 874
R+ + ++ +E ++ + +T+ E + K+ + V LE T+ S + +
Sbjct: 14884 RSVATQWETDVQIQQEGQEPIETTGHITKKSEEEISAKKTKQPIVTKLEDTLTSEVQEMR 14943
Query: 875 QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDD 1054
+++ V K ++ LE + + E E +E L+ + + + L + D
Sbjct: 14944 DMEIEDVARMKTMMKMEKDQLEQAKSDIQRQMEEFERNMEETLKEKS-RNEETLLQLLHD 15002
Query: 1055 KESIMNDLDHVKAERQ----VLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAV 1222
K+ + N LD E + + ++ +ETT + + +
Sbjct: 15003 KDDLSNTLDEKSKEIENITVTFKRNIAQLETTIAMMKKD--------------------- 15041
Query: 1223 KQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRI-SELEEAISILTDKAKKLLK 1399
K+ +E +L L+ T + E++ G DD NE E K +ELE+ + + KK +
Sbjct: 15042 KENIENELLQLKQTEQEREIQRGTDDTSNERENYDEKVTYKTELED-----SKEKKKPDR 15096
Query: 1400 DINIWLSEVTELQEDLNKESKEKQDLEKRVLELT 1501
D ++ L++ + D +E++ + + VL+LT
Sbjct: 15097 DSSLKLTDADSAKTDGEREAQTLETKVQDVLQLT 15130
Score = 63.5 bits (153), Expect = 4e-07
Identities = 113/537 (21%), Positives = 220/537 (40%), Gaps = 46/537 (8%)
Frame = +2
Query: 26 DFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTL--------- 178
+ E T NDE+ EK I + + +L + LE ADLE K +
Sbjct: 8406 NMEKTYEQQNDEIQKEKQQ---IESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLA 8462
Query: 179 -NDELERKKDDNNAIIK-------KALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXX 334
N+ LER+K D II+ +A +R ++ A A +RD E+ M +
Sbjct: 8463 ENELLEREKADVIKIIENLESLREEATRERATET-AQATRRDSEELMQKMEALSMEDFQE 8521
Query: 335 XXXXXXI--------VSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSH 490
+ + L+ ++L EL+K K D + DL ++T +EI+ H
Sbjct: 8522 ASKNQMVELKRQIDKLIELKADLLQQQTELKKTKADLKQQMDDL------EKTRSEILKH 8575
Query: 491 ---LESKSRSLKEHFLREEEDEVLERSASNLAIMK----AIREEELRKEKDGKSALVENG 649
+SK+R L+ ++ ++D+ LE L + K +R E + ++KD +
Sbjct: 8576 EKDTDSKTRELELIEIQRQKDD-LETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKM---- 8630
Query: 650 EGCEAEKQGLEKTVLERRASNLDTMDAIHE------EELRKEKVDKSALTENGEGCEAEK 811
K V+ +R D M+ I EE+ +E+ + L N + +
Sbjct: 8631 -----------KQVIRKR----DEMEKIRSDIANATEEINRERQELEILRNNVQSARHDF 8675
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
+ + +LE ++ D++R++ E + + +L+ E+
Sbjct: 8676 ELLLERTANLED-----EESAATDIERLVLEVVKIREMVRNLKG--------------EM 8716
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVS-------DMETTYSTL 1150
ER++E S + DE K + + + D+ ++ L ++ ++E + L
Sbjct: 8717 ERRMEKSKV-EIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEKMRAEL 8775
Query: 1151 NNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTL 1330
+ Q++ E ER+ LE +K + + D+E +E K++ + Q
Sbjct: 8776 AEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKY 8835
Query: 1331 KKRISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLN-KESKEKQDLEKRVLEL 1498
K+ + + E +LT K+ L +N + ++ + E++N + K++ +LE EL
Sbjct: 8836 KEELQSVTE--ELLT--KKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL 8888
Score = 63.5 bits (153), Expect = 4e-07
Identities = 118/582 (20%), Positives = 218/582 (37%), Gaps = 78/582 (13%)
Frame = +2
Query: 2 QALENKVAD-FEATIATLND--ELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKT 172
Q LE KV D + T T D EL +E ++K I+ + N + Q L+ + E K+
Sbjct: 15117 QTLETKVQDVLQLTDYTTQDQEELHDEMENKMKIILELNEAKKDLQKLKEECRSAEEEKS 15176
Query: 173 TLNDELERKKDDNNAIIKKALD-----KRISDLKADAPQ--------------------- 274
+ + LER+++ + + L ++ +K + Q
Sbjct: 15177 VIMESLERRRNSLEKVQSEVLSLTQEIDHLAQIKTEMQQIEIKMQIQTRSVATQWETDVQ 15236
Query: 275 ----RDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDL 442
++ + + V+ LE L E+Q+ +D ++D+
Sbjct: 15237 IQQGQEATETTGHITKKSEEEISAKKTKQPTVTKLEDT---LTSEVQEMRDSLNKEMEDV 15293
Query: 443 VAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIRE-EELRKEK 619
+ + + + +S ++ E F R E+ + E+S + +++ + E+L
Sbjct: 15294 ARMKTIMKMEKDQLEQAKSDIQTQMEEFERNMEEAMEEKSRNEEKLLQLTHDKEDLSNTL 15353
Query: 620 DGKSALVENG----------------------EGCEAEKQGLEKTVLERRASNLDTMDAI 733
D K+ +EN E E E L++T ER T D
Sbjct: 15354 DKKNKEIENNTETSLKKIAQLETTIVLMKKDKENIENELLQLKQTEQEREIQR-GTDDTS 15412
Query: 734 HEEELRKEKVD-KSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQ 910
+E E EKV K+ L +N E +K+ + L L D+ + D +R E Q
Sbjct: 15413 NEREKYDEKVTYKTELEDNKE----KKKPDRDSSLKLTDA-----DSAKTDGER---EAQ 15460
Query: 911 ALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVK 1090
LE + D+ T +QE ELH E ++K I+ +L+ K
Sbjct: 15461 TLETKVQDVLQLTDDTTQDQE-------------------ELHDEMENKMKIILELNEAK 15501
Query: 1091 AERQVLESKVSDMETTYSTLNNELQQKMDDNE-------AFLNERDGLEAVKQGLEKRVL 1249
+ Q L+ K E S + L+++ + E E + L +K +++
Sbjct: 15502 KDLQKLKEKCRSAEEEKSVIMESLERRRNSLEKVQSEVLTLTQEIEHLAQIKTEMQQIET 15561
Query: 1250 DLEATIHDIEMKTGKDDDYNEAEKQTLKKR---ISELEEAISILTDKAKKLLKDINIWLS 1420
++ + + D + ++ + R + EE IS K + K + S
Sbjct: 15562 KMQRQTRSVATQWETDVQIQQEGQEATETRGHITKKSEEEISAKKTKQPTVTKLEDTLTS 15621
Query: 1421 EVTELQEDLNKESK-----------EKQDLEKRVLELTSKLE 1513
EV E+++ LNKE + EK LE+ +L ++E
Sbjct: 15622 EVQEMRDSLNKEMEDVERMKTMMKMEKDQLEQAKSDLQRQME 15663
Score = 61.6 bits (148), Expect = 1e-06
Identities = 89/490 (18%), Positives = 194/490 (39%), Gaps = 3/490 (0%)
Frame = +2
Query: 98 NDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQR 277
++ ++ EA Q AD+E ELE+ KD+ K + K DL+ +
Sbjct: 1701 DELSLREATLQTATQTTADMELQLELQKQELEQTKDEMER-TKLEVQKGWVDLQTQIAES 1759
Query: 278 DQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEP 457
++++M + +++ + ++ E+ E D K L K+ E
Sbjct: 1760 REKEEMVRI---------ELEKARDVLNRIRQDVET--EKQTMEADLKFTLAKEFENLEA 1808
Query: 458 GKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSAL 637
++ + + LE+ L + E +ERS N+ +E + ++ L
Sbjct: 1809 QRKMMEDEKRALENMKYEL------QRESGYIERSKHNM-------HDERQNMENWAEKL 1855
Query: 638 VENGEGCEAEKQGLE--KTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEK 811
+ E E ++ ++ +T R +L+ + ++E L + K L + E +K
Sbjct: 1856 KQEWEELEKKRHDMQQLQTERSREIKDLENLRELNELTLNQIKTKSDVLEKISELNSQQK 1915
Query: 812 QGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEI 991
D ++ + ++ + L++ +DL + + D Q E
Sbjct: 1916 ------------------DEIENEKSKIKIREYDLQQMQTDLNRQQKEMQDIQNAVFME- 1956
Query: 992 ERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAER-QVLESKVSDMETTYSTLNNELQQ 1168
+ +L+ S ++L + D + N+ D++ ER ++E K+ LN EL+
Sbjct: 1957 KSELKKSQDEIAEQLKQVGDMMQFTQNEKDNLDRERAAIIEQKLQMERDMTHLLNRELES 2016
Query: 1169 KMDDNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISE 1348
+ LNE+ LE + L + + DLE +++ ++ + + ++Q++ + +
Sbjct: 2017 LKLVKKEVLNEKRLLEDCRISLMRDMQDLE----QMKINLEREKEEMQLQRQSIAEEKDK 2072
Query: 1349 LEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCICG 1528
LE + L + +KL D ++ + +L KE E ++ + ++K G
Sbjct: 2073 LESVLQTLAEDTEKLRIDTLAEKQKLEDAAVELQKERDEIMNIAEETKRKREDVDKIRVG 2132
Query: 1529 ARDGLSTIKE 1558
T K+
Sbjct: 2133 IEKQEITFKD 2142
Score = 61.2 bits (147), Expect = 2e-06
Identities = 118/559 (21%), Positives = 227/559 (40%), Gaps = 54/559 (9%)
Frame = +2
Query: 8 LENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLE--------- 160
LE A E L+ EL K+ I ++R LE K L+ K D+E
Sbjct: 8007 LEQDKAYMEENKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYE 8066
Query: 161 ----AAKTTLNDELERKKDDNNAIIKKA------LDKRISDLKADAPQRDQEDD---MNA 301
A + + N +++ D+ NA ++K D+ + K + + E + A
Sbjct: 8067 KQKYAERKSENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKARAETERVKQGA 8126
Query: 302 LIXXXXXXXXXXXXXXXIVSNLEVNILILHEELQKEKDDKTALIK--DLVAAEPGKRTVN 475
I + ++ N+ E ++K+K + + DL+ A+ K+
Sbjct: 8127 KIPETQQIEQSLQKERDYIEDIRRNLFKKEEAIEKDKAEIRLRHQELDLIQAKVVKQKEE 8186
Query: 476 EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEG 655
+ +ES+ +E + +E LE + + I + L+ E DGK V+N
Sbjct: 8187 MVKQKIESEREIQQEKKKLQRSEEELEDKMQKIK-REMIELKLLQDETDGKRKDVDN--- 8242
Query: 656 CEAEKQGLEKTVLERRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVL 835
+ + R+ L+ M A E +K +VD+ L + E K ++
Sbjct: 8243 --------KMRQVARKRDELEKMKADVESASKKLEVDRVMLNTERDELERIKTESQRATE 8294
Query: 836 DLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL--EAKNASLTDNQEGHEAEIERKLEA 1009
++ + A +R D + EK+ + R L EA+ AS HE E+ + E
Sbjct: 8295 HMQ------SHAEERAGD--LGEKEPVNTRIQRLIQEAEKASKMAWSTKHEPEMRMQREV 8346
Query: 1010 S----NLTHND----------ELHKEKDDKESIMNDLDHVKAERQVLE-------SKVSD 1126
S ++ D E+ ++ + +++ + ER LE + +
Sbjct: 8347 SVEEESVERQDMSANMQRMILEIEHARETLRGMKDEVQAARKERSELENMKLEFLTMKKN 8406
Query: 1127 METTYSTLNNELQ---QKMDDNEAFLN-ERDGLEAVKQGLE--KRVLDLEATIHDIEMKT 1288
ME TY N+E+Q Q+++ ++ L+ ER+ LE + LE K+++ L+ + K
Sbjct: 8407 MEKTYEQQNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALD------KQKL 8460
Query: 1289 GKDDDYNEAEKQTLKKRISELEEAISILT-DKAKKLLKDINIWLSEVTELQEDLNKESKE 1465
+++ E EK + K I LE T ++A + + E+ + E L+ E +
Sbjct: 8461 LAENELLEREKADVIKIIENLESLREEATRERATETAQATRRDSEELMQKMEALSMEDFQ 8520
Query: 1466 KQDLEKRVLELTSKLEKCI 1522
+ + +++EL +++K I
Sbjct: 8521 EAS-KNQMVELKRQIDKLI 8538
Score = 60.8 bits (146), Expect = 2e-06
Identities = 117/551 (21%), Positives = 209/551 (37%), Gaps = 81/551 (14%)
Frame = +2
Query: 56 DELLNEKDDKKCIVNDRNILEAAKQ--ALEYKVADLEAAK---TTLNDELERKKDD--NN 214
++LL E +K+ ND + E K+ ALE + D+ K +L +E+ K+ + N
Sbjct: 14082 NDLLREDLEKQRKRNDLTLQELRKEKMALEQMITDITKEKDAVASLQNEVSLKQHELKNK 14141
Query: 215 AIIKKALDKRISDLKADAPQRD-----QEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNI 379
K + DL+ R Q+ +++ I ++LE
Sbjct: 14142 ETELDEQRKEMDDLRMQLEMRQNSTNKQQQEVDVFIVENMKMR----------NDLESMK 14191
Query: 380 LILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLK---EHFLREEEDEV 550
+L EE ++ +D+ P K + LE + +K EH +E E
Sbjct: 14192 TLLDEERRQLQDNIKTFEDQKNVLHPSKTDAVQQTDELEKFTTDIKTEKEHVEKERE--- 14248
Query: 551 LERSASNLAIMKAIRE--------EELRKEKDGKSALVENGEGCEAE----KQGLEKTVL 694
E N I+K+ E E ++E GK A +E+ E A+ ++ V
Sbjct: 14249 -EIDVLNKEIIKSKEELQSLNLEIEMFKQEIAGKRAQIESLEQLRADLLAGADDIKTLVQ 14307
Query: 695 ERRASNLDTMDAIHEEELRKE-KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA 871
+ ++ + E EL+ + K+ L E EAEK E + L+ + D
Sbjct: 14308 TEKQMAIEDTEKKTEVELQMNLQKQKNELEELRNTIEAEKHQVENRKIMLDKQQKEVEDI 14367
Query: 872 LQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKL---------------- 1003
+ + +E+ LEK S+L + L + + + E+ER L
Sbjct: 14368 MTV----IKSERDVLEKEKSELNKLSHVLNEKVQREQEELERLLEKERDDIENCKKIIES 14423
Query: 1004 ----------EASNLTHNDELHKEK----DDKESIMNDLDHVKAER-------QVLESKV 1120
E L E+ E+ DK I + +H++ E+ L+ ++
Sbjct: 14424 EKQSIERERAELKRLKEEVEVQHERTLLQQDKNMIQKEKEHLEGEKARTTEEIHNLKEEI 14483
Query: 1121 SDMETTYSTLNNELQQKMDDNEAF-----LNERDGLEAVKQGLEKRVL-----------D 1252
+ LN E++ K + E + D L+ L + ++
Sbjct: 14484 KRKSSELDMLNKEIEAKRQEEELHGLPEEIEIEDHLKKEDDVLREEIIKKQQTDASQKFQ 14543
Query: 1253 LEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTE 1432
L+ T D E +T D+ +T ++R LEE ++ T K ++K + SEV E
Sbjct: 14544 LKTTSRDAETQTSLDE-----ITKTDERRQRALEETVA-TTAKQPIVIKLEDTLTSEVQE 14597
Query: 1433 LQEDLNKESKE 1465
+++ LN E KE
Sbjct: 14598 MRDHLNNEIKE 14608
Score = 60.5 bits (145), Expect = 3e-06
Identities = 112/543 (20%), Positives = 217/543 (39%), Gaps = 48/543 (8%)
Frame = +2
Query: 14 NKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN-DEL 190
+K+ + +A + EL K D K ++D LE + + D ++ L E+
Sbjct: 8535 DKLIELKADLLQQQTELKKTKADLKQQMDD---LEKTRSEILKHEKDTDSKTRELELIEI 8591
Query: 191 ERKKDDNNAIIKK-ALDKR-ISDLKADA--PQRDQEDDMNALIXXXXXXXXXXXXXXXIV 358
+R+KDD I+K L+KR + L+++ ++D + M +I
Sbjct: 8592 QRQKDDLETRIQKLTLEKRDLEVLRSEIVLEKKDLDQKMKQVIRKRDEMEKIRSDIANAT 8651
Query: 359 SNLE---VNILILHEELQKEKDD------KTALIKDLVAAEPG-KRTVNEIVSHLESKSR 508
+ + IL +Q + D +TA ++D +A +R V E+V + R
Sbjct: 8652 EEINRERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERLVLEVVK-IREMVR 8710
Query: 509 SLK---EHFLREEEDEVLERSASNLAIMKAIRE-EELRKEKDGKSALVENGEGCEAEKQG 676
+LK E + + + E+ E+ I + I++ ++R+ G +E + E +
Sbjct: 8711 NLKGEMERRMEKSKVEIDEKEIFKSEIQRFIQDIGQIRENLGGLGEEIEKTRRDKRELEK 8770
Query: 677 LEKTVLERRASNLDTMDAIHEE---------ELRKEKVDKSALTENGEGCEAEKQGPEKT 829
+ + E++ + +H+E E+ +EK D E E +++ E T
Sbjct: 8771 MRAELAEKQQEQESMREMLHKEREELEQLKDEINREKEDVEIRRELVEAVIDKEEMKEFT 8830
Query: 830 -VLDLEPTIPSLNDAL---QRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIER 997
+ + + S+ + L +RDLD++ ++ Q L + ++ ++ EG E+ +
Sbjct: 8831 DIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFEL-K 8889
Query: 998 KLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMD 1177
K E DEL + E I N D ++ + K DM+ L E Q+
Sbjct: 8890 KGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRQEKQEMDL 8949
Query: 1178 DNEAFLNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKR------ 1339
+R+ LE Q L ++E +I + + D ++ KQ ++KR
Sbjct: 8950 FRSELQRQREDLETSIQKLTHEKREMEVLRSEIVL---EKKDLDQKMKQVIRKRDEMEKI 9006
Query: 1340 ----------ISELEEAISILTDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
I + + IL D + +D + E +L E D+E+ V
Sbjct: 9007 RFDIANARVEIDGERQELEILRDNVQSARQD----FERLVERTANLEVEESAATDIERLV 9062
Query: 1490 LEL 1498
LE+
Sbjct: 9063 LEV 9065
>ref|XP_006560777.1| PREDICTED: sporulation-specific protein 15 isoform X2 [Apis
mellifera]
Length = 1934
Score = 100 bits (250), Expect = 2e-18
Identities = 125/518 (24%), Positives = 229/518 (44%), Gaps = 11/518 (2%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ LE K+ D +A+++ ++L NE +D++ + ALE K+++LE ++ L
Sbjct: 258 ETLEAKL-DEQASLSAELEDLRNELEDQRAKNKELEACCKDMDALEKKLSELEKKRSELE 316
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
ELE + + + K+ LD + ++ + ++D+ D
Sbjct: 317 KELEDNRGELERLQKENLDLK-DVIEVERAEKDKLRD----------------------- 352
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
L EE +K K+D L L + LE ++ L E +
Sbjct: 353 --------LLEESKKLKEDNENLWAQLERLRGENDDLMGQKKALEDLNKQLNE------D 398
Query: 542 DEVLERSASNL-AIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 718
+E ++R+ NL A + ++ E E++ + L EN E+ K+ LE+T+ E NL
Sbjct: 399 NESMKRTMGNLEARIDSLSNELSNVERERDALLDEN----ESVKRELERTLTENE--NLK 452
Query: 719 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 898
T +E+L K K +++ L N + + E + L+ + +L D L+
Sbjct: 453 TELDKADEQLDKLKTERNELQRNFDTMKLENE-------TLKENVKALKDDLEES----- 500
Query: 899 AEKQALEKRCSDLEAKNASLTDNQEGHEAEI-ERKLEASNL-THNDELHKEKDDKESIMN 1072
++ +++A +L D +E +AE E + NL T N EL KE DD + +
Sbjct: 501 ------KREVDEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGELKKENDDLRTRSS 554
Query: 1073 DLDH----VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEK 1240
+L+H VK E +ES+ +D+ L EL++ + E E + ++K L+K
Sbjct: 555 ELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDKKEIEQLKLE---ISSLKDALDK 611
Query: 1241 RVLDLEATIHDIEMKTGKDDDYNEA----EKQTLKKRISELEEAISILTDKAKKLLKDIN 1408
V ++E + E K K+ EA E LK + +ELEE ++ ++ K+ +
Sbjct: 612 CVDEMEKLKVENE-KLKKEGMKVEATWLEENVNLKAKNTELEENLANTVNELDKMRSENA 670
Query: 1409 IWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCI 1522
LSE+ L+++L KE L+ + + L KC+
Sbjct: 671 DLLSELNRLKQELESGRKEIDQLKSEIGSMKDALGKCV 708
Score = 87.0 bits (214), Expect = 3e-14
Identities = 125/526 (23%), Positives = 226/526 (42%), Gaps = 27/526 (5%)
Frame = +2
Query: 2 QALENKVADFEATI-----ATLNDELLNEK--DDKKCIVNDRNILEAAKQALEYKVADLE 160
+ L+ K+AD EA I EL NEK D + ++ D N + AK+A+E + L+
Sbjct: 1048 EQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVLKDLNECQIAKKAIESDLIKLK 1107
Query: 161 AAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 340
K LN N + LD++ L+A+ +D+ D
Sbjct: 1108 NEKDDLNK--------NMTDLTSQLDRQKRSLEAEKSAKDRGDVQ--------------- 1144
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 520
+++L + L +EL+K + D + K ++++ L S L +
Sbjct: 1145 -----IASLNSELEALKKELEKLRADNSKY----------KSEIDDLGKQLASAKNELND 1189
Query: 521 HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLER 700
+E++ +N A+ + + LR KD S L +G ++E L L+
Sbjct: 1190 C-----REEIVVLKNANSALRSEL--DPLRSLKDDYSRLTTELDGLKSENTKL----LQD 1238
Query: 701 RASNLDTMDAIHEE-ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQ 877
+ S D + E + ++ ++D+ T +AEK EK DL+ + ND LQ
Sbjct: 1239 KRSLEDEFGKLRGEGDGQRVEIDRLRTT-----LDAEKTAAEKLKSDLQ-SCKDENDKLQ 1292
Query: 878 -------RDLDRVMAEKQALE-------KRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1015
R LD++ E L+ K+ D+EAK SL + AE E ++
Sbjct: 1293 TQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEELVK--- 1349
Query: 1016 LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 1195
EL++ ++D ++ N+L+ + +E + ++++ L EL + D+N+
Sbjct: 1350 -----ELYRTREDLNNLRNELEKQTGVKDTMEKESTNLKEELKALKEELNKTRDENDRLK 1404
Query: 1196 NERDGLEAVKQGLEKR---VLDLEATI-HDIEMKTGKDDDYNEAEKQTLKKRISELEEAI 1363
NE D L A L K+ + D A + +DIE ++ + ++ E K + +E +
Sbjct: 1405 NENDKLNAEIARLNKQLDALKDESANLKNDIENLNERNAELSK-ELAVAKDNLMGMETRL 1463
Query: 1364 SILTDKAKKLLKDINIWLSEVTELQEDLNKESKE-KQDLEKRVLEL 1498
S L K +K+ I L + + +DL ++ KE K++L+K EL
Sbjct: 1464 SNL-KKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELDKPSPEL 1508
Score = 77.0 bits (188), Expect = 3e-11
Identities = 114/524 (21%), Positives = 222/524 (42%), Gaps = 34/524 (6%)
Frame = +2
Query: 47 TLNDE---LLNEKDDKKCIVND-RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNN 214
+L DE L E D ++ ++ R L+A K A E +DL++ K ND+L+ + ++
Sbjct: 1241 SLEDEFGKLRGEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKDE-NDKLQTQINE-- 1297
Query: 215 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHE 394
+K++LDK ++ D +R+ ++ L ++E + L
Sbjct: 1298 --MKRSLDKMGTE--NDRLKREVDESRKKL------------------EDMEAKVKSLEN 1335
Query: 395 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 574
+L +K L+K+L + +N + + LE K +K+ +E+ ++NL
Sbjct: 1336 QLSNLSAEKEELVKELYRT---REDLNNLRNELE-KQTGVKD---------TMEKESTNL 1382
Query: 575 AIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV--LERRASNL-DTMDAIHEEE 745
+EEL K +D L + AE L K + L+ ++NL + ++ ++E
Sbjct: 1383 KEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNERN 1442
Query: 746 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQR--DLDRVMAE-KQAL 916
K + + +N G E +K D++ I +L D++Q DL R + E K+ L
Sbjct: 1443 AELSK-ELAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKEL 1501
Query: 917 EKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDH---- 1084
+K +L+ L+++N D+L +++ ++ NDLD+
Sbjct: 1502 DKPSPELDT-------------------LKSTNKKLQDDLDNARNESLNLKNDLDNLQND 1542
Query: 1085 ----------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 1234
VK ER + + +E + E ++ ++ NE E D L
Sbjct: 1543 YNNLQTELADVKEERDTFRERAAALEKDLVRVKRENEELVEQNETLRTELDDCRGENNRL 1602
Query: 1235 EKRVLDLEA---TIHDIEMKTGKDDDYNEAEKQTLKKRISEL-------EEAISILTDKA 1384
K + L++ + D + + + + + LKK S+L E + +K
Sbjct: 1603 LKELEKLKSENVKLQDNLINARSEGERLKEDLNKLKKDYSDLRTDLTKAREDRDVRKEKD 1662
Query: 1385 KKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+L K+I+ + +L+ DL KE + L K+V +L ++ +K
Sbjct: 1663 MELDKEIDELKAVNAKLKSDLYDCQKENEKLRKQVTKLKAENDK 1706
Score = 75.9 bits (185), Expect = 7e-11
Identities = 118/534 (22%), Positives = 213/534 (39%), Gaps = 53/534 (9%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
+ T ND L E D+ + + D +EA ++LE ++++L A K L EL R ++D N +
Sbjct: 1305 MGTENDRLKREVDESRKKLED---MEAKVKSLENQLSNLSAEKEELVKELYRTREDLNNL 1361
Query: 221 ---------IKKALDKRISDLKADAPQRDQE-----DDMNALIXXXXXXXXXXXXXXXIV 358
+K ++K ++LK + +E D+ + L +
Sbjct: 1362 RNELEKQTGVKDTMEKESTNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQL 1421
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 538
L+ L +++ + L K+L A+ + +S+L+ ++ +K + E
Sbjct: 1422 DALKDESANLKNDIENLNERNAELSKELAVAKDNLMGMETRLSNLKKENDDMKNKIITLE 1481
Query: 539 EDEVLERSASNLAIMKAIRE-----EELRKEKDGKSALVENGEGCEAEKQGLEKTV--LE 697
D + E + +A +E EL K L ++ + E L+ + L+
Sbjct: 1482 -DSIQEVDDLKRQLKEAKKELDKPSPELDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQ 1540
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQ 877
+NL T EL K ++ E E + ++ +L N+ L+
Sbjct: 1541 NDYNNLQT-------ELADVKEERDTFRERAAALEKDLVRVKRENEELVEQ----NETLR 1589
Query: 878 RDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDK 1057
+LD E L K L+++N L DN +E ER E +L+K K D
Sbjct: 1590 TELDDCRGENNRLLKELEKLKSENVKLQDNLINARSEGERLKE--------DLNKLKKDY 1641
Query: 1058 ESIMNDLDHVKAERQV-------LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 1216
+ DL + +R V L+ ++ +++ + L ++L +NE + L+
Sbjct: 1642 SDLRTDLTKAREDRDVRKEKDMELDKEIDELKAVNAKLKSDLYDCQKENEKLRKQVTKLK 1701
Query: 1217 AVKQGLEKRV-LDLEATIHDIEMKTGKD-DDYNEAEKQTLK------KRISELEEAISIL 1372
A L+K + DL+ +I+ D ++Y EA K K K + L + I+ L
Sbjct: 1702 AENDKLKKALDKDLDQKETEIDKDILDDCNEYVEANKILRKNFENQLKGVQRLRDYINYL 1761
Query: 1373 TDK------AKKL-----------LKDINIWLSEVTELQEDLNKESKEKQDLEK 1483
K A KL KDI L +L ++NK +E Q+L K
Sbjct: 1762 DGKGTEPKMADKLEESEMNNPVNAKKDIEDLLKMSQDLSININKAEQEIQNLAK 1815
Score = 75.5 bits (184), Expect = 9e-11
Identities = 127/600 (21%), Positives = 228/600 (38%), Gaps = 108/600 (18%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVND-RNILEAAKQAL---EYKVADLEAAKTTLNDELERKKDD 208
+ T N EL E DD + ++ + L+ K+ L E + ADL A L ELE+ K +
Sbjct: 535 LKTENGELKKENDDLRTRSSELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDKKE 594
Query: 209 NNAI------IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLE 370
+ +K ALDK + +++ + ++ + + LE
Sbjct: 595 IEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATWLEENVNLKAKN--TELE 652
Query: 371 VNILILHEELQKEKDDKTALIKDL----VAAEPGKRTVNEIVSH---------------- 490
N+ EL K + + L+ +L E G++ ++++ S
Sbjct: 653 ENLANTVNELDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMKDALGKCVDEIE 712
Query: 491 -LESKSRSLKEHF--LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
L+++++ LK L E D + A + ++E+ K A E+ +
Sbjct: 713 KLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKLDEAKTEDSD-LR 771
Query: 662 AEKQGLEKTVLERRASNLDTMDAIHE----------EELRKEKVDKSALTENGEGC--EA 805
AE L+K LE +D + A EE+ K + S L G E
Sbjct: 772 AEVDRLKKE-LESAGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEG 830
Query: 806 EKQGPEKT-VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE 982
+ E T V D + D L + L E + L+K+ +LE++N + E +
Sbjct: 831 DSLASELTNVKDENSALKDEKDQLNKQLAENKTENERLKKQNDELESENTKIKKELESCK 890
Query: 983 AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL 1162
E L+ N +EL K + +S+ ++ + ++ E + E K+ +E S +E
Sbjct: 891 NE-NNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRARSEN 949
Query: 1163 QQKMDDNEAFLNERDGLEAVKQGLEKRVLD----------LEATIHDIEMKTGKDDDYNE 1312
++ ++ NE + L K L++ +LD LE + D+ K + N+
Sbjct: 950 EKSQNELAVLRNEANEL---KVKLDREMLDNTNMRNALKILEDQVLDLNKKLDNCREEND 1006
Query: 1313 AEKQ------------------------TLKKRISELEEAISILTDKA------------ 1384
A K+ LK+ I+ L++ I L K
Sbjct: 1007 ALKEENKDLKTKLSDTGQVVLNLKTECDNLKEDIASLQKTIEQLKQKIADQEAEIDHWKV 1066
Query: 1385 ----------------KKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+K+LKD+N ++ DL K EK DL K + +LTS+L++
Sbjct: 1067 EHCKFELDNEKLKADLEKVLKDLNECQIAKKAIESDLIKLKNEKDDLNKNMTDLTSQLDR 1126
>ref|XP_006560776.1| PREDICTED: sporulation-specific protein 15 isoform X1 [Apis
mellifera]
Length = 2064
Score = 100 bits (250), Expect = 2e-18
Identities = 125/518 (24%), Positives = 229/518 (44%), Gaps = 11/518 (2%)
Frame = +2
Query: 2 QALENKVADFEATIATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLN 181
+ LE K+ D +A+++ ++L NE +D++ + ALE K+++LE ++ L
Sbjct: 388 ETLEAKL-DEQASLSAELEDLRNELEDQRAKNKELEACCKDMDALEKKLSELEKKRSELE 446
Query: 182 DELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVS 361
ELE + + + K+ LD + ++ + ++D+ D
Sbjct: 447 KELEDNRGELERLQKENLDLK-DVIEVERAEKDKLRD----------------------- 482
Query: 362 NLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEE 541
L EE +K K+D L L + LE ++ L E +
Sbjct: 483 --------LLEESKKLKEDNENLWAQLERLRGENDDLMGQKKALEDLNKQLNE------D 528
Query: 542 DEVLERSASNL-AIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLD 718
+E ++R+ NL A + ++ E E++ + L EN E+ K+ LE+T+ E NL
Sbjct: 529 NESMKRTMGNLEARIDSLSNELSNVERERDALLDEN----ESVKRELERTLTENE--NLK 582
Query: 719 TMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVM 898
T +E+L K K +++ L N + + E + L+ + +L D L+
Sbjct: 583 TELDKADEQLDKLKTERNELQRNFDTMKLENE-------TLKENVKALKDDLEES----- 630
Query: 899 AEKQALEKRCSDLEAKNASLTDNQEGHEAEI-ERKLEASNL-THNDELHKEKDDKESIMN 1072
++ +++A +L D +E +AE E + NL T N EL KE DD + +
Sbjct: 631 ------KREVDEMKAVGDALKDKEELKDAEFRELQQNMQNLKTENGELKKENDDLRTRSS 684
Query: 1073 DLDH----VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEK 1240
+L+H VK E +ES+ +D+ L EL++ + E E + ++K L+K
Sbjct: 685 ELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDKKEIEQLKLE---ISSLKDALDK 741
Query: 1241 RVLDLEATIHDIEMKTGKDDDYNEA----EKQTLKKRISELEEAISILTDKAKKLLKDIN 1408
V ++E + E K K+ EA E LK + +ELEE ++ ++ K+ +
Sbjct: 742 CVDEMEKLKVENE-KLKKEGMKVEATWLEENVNLKAKNTELEENLANTVNELDKMRSENA 800
Query: 1409 IWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEKCI 1522
LSE+ L+++L KE L+ + + L KC+
Sbjct: 801 DLLSELNRLKQELESGRKEIDQLKSEIGSMKDALGKCV 838
Score = 87.0 bits (214), Expect = 3e-14
Identities = 125/526 (23%), Positives = 226/526 (42%), Gaps = 27/526 (5%)
Frame = +2
Query: 2 QALENKVADFEATI-----ATLNDELLNEK--DDKKCIVNDRNILEAAKQALEYKVADLE 160
+ L+ K+AD EA I EL NEK D + ++ D N + AK+A+E + L+
Sbjct: 1178 EQLKQKIADQEAEIDHWKVEHCKFELDNEKLKADLEKVLKDLNECQIAKKAIESDLIKLK 1237
Query: 161 AAKTTLNDELERKKDDNNAIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXX 340
K LN N + LD++ L+A+ +D+ D
Sbjct: 1238 NEKDDLNK--------NMTDLTSQLDRQKRSLEAEKSAKDRGDVQ--------------- 1274
Query: 341 XXXXIVSNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKE 520
+++L + L +EL+K + D + K ++++ L S L +
Sbjct: 1275 -----IASLNSELEALKKELEKLRADNSKY----------KSEIDDLGKQLASAKNELND 1319
Query: 521 HFLREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLER 700
+E++ +N A+ + + LR KD S L +G ++E L L+
Sbjct: 1320 C-----REEIVVLKNANSALRSEL--DPLRSLKDDYSRLTTELDGLKSENTKL----LQD 1368
Query: 701 RASNLDTMDAIHEE-ELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQ 877
+ S D + E + ++ ++D+ T +AEK EK DL+ + ND LQ
Sbjct: 1369 KRSLEDEFGKLRGEGDGQRVEIDRLRTT-----LDAEKTAAEKLKSDLQ-SCKDENDKLQ 1422
Query: 878 -------RDLDRVMAEKQALE-------KRCSDLEAKNASLTDNQEGHEAEIERKLEASN 1015
R LD++ E L+ K+ D+EAK SL + AE E ++
Sbjct: 1423 TQINEMKRSLDKMGTENDRLKREVDESRKKLEDMEAKVKSLENQLSNLSAEKEELVK--- 1479
Query: 1016 LTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFL 1195
EL++ ++D ++ N+L+ + +E + ++++ L EL + D+N+
Sbjct: 1480 -----ELYRTREDLNNLRNELEKQTGVKDTMEKESTNLKEELKALKEELNKTRDENDRLK 1534
Query: 1196 NERDGLEAVKQGLEKR---VLDLEATI-HDIEMKTGKDDDYNEAEKQTLKKRISELEEAI 1363
NE D L A L K+ + D A + +DIE ++ + ++ E K + +E +
Sbjct: 1535 NENDKLNAEIARLNKQLDALKDESANLKNDIENLNERNAELSK-ELAVAKDNLMGMETRL 1593
Query: 1364 SILTDKAKKLLKDINIWLSEVTELQEDLNKESKE-KQDLEKRVLEL 1498
S L K +K+ I L + + +DL ++ KE K++L+K EL
Sbjct: 1594 SNL-KKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKELDKPSPEL 1638
Score = 77.0 bits (188), Expect = 3e-11
Identities = 114/524 (21%), Positives = 222/524 (42%), Gaps = 34/524 (6%)
Frame = +2
Query: 47 TLNDE---LLNEKDDKKCIVND-RNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNN 214
+L DE L E D ++ ++ R L+A K A E +DL++ K ND+L+ + ++
Sbjct: 1371 SLEDEFGKLRGEGDGQRVEIDRLRTTLDAEKTAAEKLKSDLQSCKDE-NDKLQTQINE-- 1427
Query: 215 AIIKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNILILHE 394
+K++LDK ++ D +R+ ++ L ++E + L
Sbjct: 1428 --MKRSLDKMGTE--NDRLKREVDESRKKL------------------EDMEAKVKSLEN 1465
Query: 395 ELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNL 574
+L +K L+K+L + +N + + LE K +K+ +E+ ++NL
Sbjct: 1466 QLSNLSAEKEELVKELYRT---REDLNNLRNELE-KQTGVKD---------TMEKESTNL 1512
Query: 575 AIMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTV--LERRASNL-DTMDAIHEEE 745
+EEL K +D L + AE L K + L+ ++NL + ++ ++E
Sbjct: 1513 KEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQLDALKDESANLKNDIENLNERN 1572
Query: 746 LRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQR--DLDRVMAE-KQAL 916
K + + +N G E +K D++ I +L D++Q DL R + E K+ L
Sbjct: 1573 AELSK-ELAVAKDNLMGMETRLSNLKKENDDMKNKIITLEDSIQEVDDLKRQLKEAKKEL 1631
Query: 917 EKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDH---- 1084
+K +L+ L+++N D+L +++ ++ NDLD+
Sbjct: 1632 DKPSPELDT-------------------LKSTNKKLQDDLDNARNESLNLKNDLDNLQND 1672
Query: 1085 ----------VKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGL 1234
VK ER + + +E + E ++ ++ NE E D L
Sbjct: 1673 YNNLQTELADVKEERDTFRERAAALEKDLVRVKRENEELVEQNETLRTELDDCRGENNRL 1732
Query: 1235 EKRVLDLEA---TIHDIEMKTGKDDDYNEAEKQTLKKRISEL-------EEAISILTDKA 1384
K + L++ + D + + + + + LKK S+L E + +K
Sbjct: 1733 LKELEKLKSENVKLQDNLINARSEGERLKEDLNKLKKDYSDLRTDLTKAREDRDVRKEKD 1792
Query: 1385 KKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+L K+I+ + +L+ DL KE + L K+V +L ++ +K
Sbjct: 1793 MELDKEIDELKAVNAKLKSDLYDCQKENEKLRKQVTKLKAENDK 1836
Score = 75.9 bits (185), Expect = 7e-11
Identities = 118/534 (22%), Positives = 213/534 (39%), Gaps = 53/534 (9%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAI 220
+ T ND L E D+ + + D +EA ++LE ++++L A K L EL R ++D N +
Sbjct: 1435 MGTENDRLKREVDESRKKLED---MEAKVKSLENQLSNLSAEKEELVKELYRTREDLNNL 1491
Query: 221 ---------IKKALDKRISDLKADAPQRDQE-----DDMNALIXXXXXXXXXXXXXXXIV 358
+K ++K ++LK + +E D+ + L +
Sbjct: 1492 RNELEKQTGVKDTMEKESTNLKEELKALKEELNKTRDENDRLKNENDKLNAEIARLNKQL 1551
Query: 359 SNLEVNILILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREE 538
L+ L +++ + L K+L A+ + +S+L+ ++ +K + E
Sbjct: 1552 DALKDESANLKNDIENLNERNAELSKELAVAKDNLMGMETRLSNLKKENDDMKNKIITLE 1611
Query: 539 EDEVLERSASNLAIMKAIRE-----EELRKEKDGKSALVENGEGCEAEKQGLEKTV--LE 697
D + E + +A +E EL K L ++ + E L+ + L+
Sbjct: 1612 -DSIQEVDDLKRQLKEAKKELDKPSPELDTLKSTNKKLQDDLDNARNESLNLKNDLDNLQ 1670
Query: 698 RRASNLDTMDAIHEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQ 877
+NL T EL K ++ E E + ++ +L N+ L+
Sbjct: 1671 NDYNNLQT-------ELADVKEERDTFRERAAALEKDLVRVKRENEELVEQ----NETLR 1719
Query: 878 RDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDK 1057
+LD E L K L+++N L DN +E ER E +L+K K D
Sbjct: 1720 TELDDCRGENNRLLKELEKLKSENVKLQDNLINARSEGERLKE--------DLNKLKKDY 1771
Query: 1058 ESIMNDLDHVKAERQV-------LESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLE 1216
+ DL + +R V L+ ++ +++ + L ++L +NE + L+
Sbjct: 1772 SDLRTDLTKAREDRDVRKEKDMELDKEIDELKAVNAKLKSDLYDCQKENEKLRKQVTKLK 1831
Query: 1217 AVKQGLEKRV-LDLEATIHDIEMKTGKD-DDYNEAEKQTLK------KRISELEEAISIL 1372
A L+K + DL+ +I+ D ++Y EA K K K + L + I+ L
Sbjct: 1832 AENDKLKKALDKDLDQKETEIDKDILDDCNEYVEANKILRKNFENQLKGVQRLRDYINYL 1891
Query: 1373 TDK------AKKL-----------LKDINIWLSEVTELQEDLNKESKEKQDLEK 1483
K A KL KDI L +L ++NK +E Q+L K
Sbjct: 1892 DGKGTEPKMADKLEESEMNNPVNAKKDIEDLLKMSQDLSININKAEQEIQNLAK 1945
Score = 75.5 bits (184), Expect = 9e-11
Identities = 127/600 (21%), Positives = 228/600 (38%), Gaps = 108/600 (18%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVND-RNILEAAKQAL---EYKVADLEAAKTTLNDELERKKDD 208
+ T N EL E DD + ++ + L+ K+ L E + ADL A L ELE+ K +
Sbjct: 665 LKTENGELKKENDDLRTRSSELEHKLDNVKKELDKVESENADLRAKIDNLEKELEKDKKE 724
Query: 209 NNAI------IKKALDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLE 370
+ +K ALDK + +++ + ++ + + LE
Sbjct: 725 IEQLKLEISSLKDALDKCVDEMEKLKVENEKLKKEGMKVEATWLEENVNLKAKN--TELE 782
Query: 371 VNILILHEELQKEKDDKTALIKDL----VAAEPGKRTVNEIVSH---------------- 490
N+ EL K + + L+ +L E G++ ++++ S
Sbjct: 783 ENLANTVNELDKMRSENADLLSELNRLKQELESGRKEIDQLKSEIGSMKDALGKCVDEIE 842
Query: 491 -LESKSRSLKEHF--LREEEDEVLERSASNLAIMKAIREEELRKEKDGKSALVENGEGCE 661
L+++++ LK L E D + A + ++E+ K A E+ +
Sbjct: 843 KLKTENKDLKSEVQGLESERDRLTNEVADLKPKISELQEKLTDASKKLDEAKTEDSD-LR 901
Query: 662 AEKQGLEKTVLERRASNLDTMDAIHE----------EELRKEKVDKSALTENGEGC--EA 805
AE L+K LE +D + A EE+ K + S L G E
Sbjct: 902 AEVDRLKKE-LESAGKEIDQLKAEMNSLKNGLNKCVEEMEKLTNENSELKSQVHGLRGEG 960
Query: 806 EKQGPEKT-VLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDLEAKNASLTDNQEGHE 982
+ E T V D + D L + L E + L+K+ +LE++N + E +
Sbjct: 961 DSLASELTNVKDENSALKDEKDQLNKQLAENKTENERLKKQNDELESENTKIKKELESCK 1020
Query: 983 AEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESKVSDMETTYSTLNNEL 1162
E L+ N +EL K + +S+ ++ + ++ E + E K+ +E S +E
Sbjct: 1021 NE-NNNLKEENNKLKEELEKLGEQLKSLNDETNKLRRELKEAEDKIQILEPQLSRARSEN 1079
Query: 1163 QQKMDDNEAFLNERDGLEAVKQGLEKRVLD----------LEATIHDIEMKTGKDDDYNE 1312
++ ++ NE + L K L++ +LD LE + D+ K + N+
Sbjct: 1080 EKSQNELAVLRNEANEL---KVKLDREMLDNTNMRNALKILEDQVLDLNKKLDNCREEND 1136
Query: 1313 AEKQ------------------------TLKKRISELEEAISILTDKA------------ 1384
A K+ LK+ I+ L++ I L K
Sbjct: 1137 ALKEENKDLKTKLSDTGQVVLNLKTECDNLKEDIASLQKTIEQLKQKIADQEAEIDHWKV 1196
Query: 1385 ----------------KKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRVLELTSKLEK 1516
+K+LKD+N ++ DL K EK DL K + +LTS+L++
Sbjct: 1197 EHCKFELDNEKLKADLEKVLKDLNECQIAKKAIESDLIKLKNEKDDLNKNMTDLTSQLDR 1256
>gb|EMD48416.1| viral Atype inclusion protein repeat-containing protein, partial
[Entamoeba histolytica KU27]
Length = 909
Score = 100 bits (249), Expect = 3e-18
Identities = 120/581 (20%), Positives = 253/581 (43%), Gaps = 77/581 (13%)
Frame = +2
Query: 50 LNDELLNEKDDKKCIVNDRNILEAAKQALEYKVADLEAAKTTLNDELERKKDDNNAIIK- 226
+N+EL + K++KK I ++N + + ++ + +E K L E+E++K+ NN +
Sbjct: 11 INNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE 70
Query: 227 --------KALDKRISDLKAD---------APQRDQEDDMNALIXXXXXXXXXXXXXXXI 355
K ++++ ++ D Q + + ++N + +
Sbjct: 71 INTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDV 130
Query: 356 VSNLEVNILILHEELQKEKDDKTALIKDL--VAAEPGKRTVN------------------ 475
+ E + L EE ++ ++KT + L + E K T
Sbjct: 131 KTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTK 190
Query: 476 --EIVSHLESKSRSLKEHFLREEEDEVLERSASNLAIMKAIREEELRKEK---------- 619
EI E K++ ++ ++E E +++ + + I K+ +EEEL K K
Sbjct: 191 ELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEK 250
Query: 620 -----------DGKSALVENGEGCEAEKQGL--EKTVLERRASNLDTMDAIHEEELRKEK 760
DG + L E + + EK+ + E ++ N+ +EE+++++
Sbjct: 251 AKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKE 310
Query: 761 -------VDKSALTENGEGCEAEKQ--GPEKTVL--DLEPTIPSLND---ALQRDLDRVM 898
+KS L + EKQ EK V+ + E I LN+ ++ +L+++
Sbjct: 311 NETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIK 370
Query: 899 AEKQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDL 1078
EKQ +E + + + + D + E+ + + N+EL + K +KE+++N+L
Sbjct: 371 TEKQEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKL-NEELTQTKQEKENVLNEL 429
Query: 1079 DHVKAERQVLESKVSDMETTYSTLNNELQQKMDDNEAFLNERDGLEAVKQGLEKRVLDLE 1258
+ +K E + + + E NN++QQ+++ NE LE K + +L
Sbjct: 430 NQIKNEFASFKEQNTQKENELKDENNKVQQELEQKN---NEVSKLEEEKGNISN---ELS 483
Query: 1259 ATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWLSEVTELQ 1438
T ++E K K + +++ K+ +EL+E + + ++ KL+ +++ +++L
Sbjct: 484 NTKQELEQK--KQEIITITQEKEEKE--NELKEQVKKIEEEKSKLITELSNGSDGISKLN 539
Query: 1439 EDLNKESKEKQDLEKRVLELTSKLEKCICGARDGLSTIKEA 1561
E+L + +EK++++K + E KLE+ L IKEA
Sbjct: 540 EELTQTKQEKEEIQKALEEEKEKLER----IETELKEIKEA 576
Score = 97.4 bits (241), Expect = 2e-17
Identities = 108/519 (20%), Positives = 230/519 (44%), Gaps = 36/519 (6%)
Frame = +2
Query: 41 IATLNDELLNEKDDKKCIVNDRNILE----AAKQALEYKVADLEAAKTTLNDELERKKDD 208
I+ LN+EL K +K+ ++N+ N ++ + K+ K +L+ + ELE+K ++
Sbjct: 408 ISKLNEELTQTKQEKENVLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNE 467
Query: 209 NNAIIKKA--LDKRISDLKADAPQRDQEDDMNALIXXXXXXXXXXXXXXXIVSNLEVNIL 382
+ + ++ + +S+ K + Q+ QE I E
Sbjct: 468 VSKLEEEKGNISNELSNTKQELEQKKQE-------------------IITITQEKEEKEN 508
Query: 383 ILHEELQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERS 562
L E+++K +++K+ LI +L G +NE ++ + + +++ EEE E LER
Sbjct: 509 ELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKAL--EEEKEKLERI 566
Query: 563 ASNLAIMKAIR---EEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAI 733
+ L +K + EEE K + K+ L + + + L +T E+ N + +++I
Sbjct: 567 ETELKEIKEAKQELEEEKNKTIEEKTNLQQELNENKKIVEELTQTKQEKEEIN-NELNSI 625
Query: 734 HEEELRKEKVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDA-------------L 874
EE+ R E+ + EN E E + E+ ++ S+ + +
Sbjct: 626 KEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGERIEI 685
Query: 875 QRDLDRVMAE-------KQALEKRCSDLEAKNASLTDNQEGHEAEIERKLEASNLTHNDE 1033
+++ DRV++E + ++K+ + + + + EG E E+ L + +T +E
Sbjct: 686 EKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLN-NQITQLNE 744
Query: 1034 LHKEKDDKESIM---NDLDHVKAERQVLESKVSDMETTYSTLNNEL----QQKMDDNEAF 1192
KEK E +M L + ++ + + + Y+ +N E Q++ NE +
Sbjct: 745 --KEKQMNEQVMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEY 802
Query: 1193 LNERDGLEAVKQGLEKRVLDLEATIHDIEMKTGKDDDYNEAEKQTLKKRISELEEAISIL 1372
+ LE K+ L DL+ + ++ K+ D + LK+ + LEE + +
Sbjct: 803 KTVNEELEKNKKELN----DLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKM 858
Query: 1373 TDKAKKLLKDINIWLSEVTELQEDLNKESKEKQDLEKRV 1489
++ KL+ +++ V++L E+L + +EK+++ +
Sbjct: 859 EEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEINNEL 897
Score = 83.2 bits (204), Expect = 4e-13
Identities = 90/434 (20%), Positives = 195/434 (44%), Gaps = 47/434 (10%)
Frame = +2
Query: 398 LQKEKDDKTALIKDLVAAEPGKRTVNEIVSHLESKSRSLKEHFLREEEDEVLERSASNLA 577
L + K +K + +L + + K+ + E + + ++++ +KE + EE+
Sbjct: 1 LTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEE----------- 49
Query: 578 IMKAIREEELRKEKDGKSALVENGEGCEAEKQGLEKTVLERRASNLDTMDAIHEEELRKE 757
K +E+ KEK+G + L + + +E+ E N + EE+ +
Sbjct: 50 --KKELLKEIEKEKEGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQ 107
Query: 758 KVDKSALTENGEGCEAEKQGPEKTVLDLEPTIPSLNDALQRDLDRVMAEKQALEKRCSDL 937
K + + + E + E EK ++D++ + + L+ + +++ EK +E + +
Sbjct: 108 K-ELNQIKEEKQKTENEK----NELVDVKTQKENELNKLKEEKEQIFNEKTTIENSLNQI 162
Query: 938 EAKNASLTDNQEGHEAEIERKLEASNLTHNDELHKEKDDKESIMNDLDHVKAERQVLESK 1117
+ LT+ +E + E++ ++A N T E++K ++K + ND D V+ E++ ++ +
Sbjct: 163 VEEKNKLTEEKESIKQELD-SIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQKE 221
Query: 1118 VSDMETTYSTLNNEL------QQKMDDNEAFL-----NERDGLEAVKQGLEKRVLDLEAT 1264
++ ++ S EL +Q+++D +A L N DGL + + ++K + E
Sbjct: 222 LNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENI 281
Query: 1265 IHDI-EMKTGKDDDYNEAEKQTLKKRISELEEAISILTDKAKKLLKDINIWL-------- 1417
+++ ++K +D+ NE K K+ I + E L ++ LL ++N
Sbjct: 282 SNELNQIKNERDNISNEFNK--TKEEIKQKENETIQLNEEKSVLLNELNQIKEEKQKIED 339
Query: 1418 ----------SEVTELQED-------LNKESKEKQDLE----------KRVLELTSKLEK 1516
+E+T+L ED LN+ EKQ++E +++ + SKL
Sbjct: 340 EKAVIQQEKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKDEKQKIEDEKSKLIT 399
Query: 1517 CICGARDGLSTIKE 1558
+ DG+S + E
Sbjct: 400 ELSNGNDGISKLNE 413