BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Paeonia22_contig00028392
         (536 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_007027193.1| Kinase superfamily protein isoform 1 [Theobr...   179   3e-43
ref|XP_007205320.1| hypothetical protein PRUPE_ppa006902mg [Prun...   167   1e-39
ref|XP_002276042.1| PREDICTED: serine/threonine-protein kinase P...   167   1e-39
gb|EXB84828.1| Serine/threonine-protein kinase PBS1 [Morus notab...   163   3e-38
gb|AGU91423.1| serine/threonine-protein kinase PBS1, partial [Ch...   162   4e-38
ref|XP_006367263.1| PREDICTED: serine/threonine-protein kinase P...   161   1e-37
ref|XP_007144514.1| hypothetical protein PHAVU_007G162300g [Phas...   160   2e-37
ref|XP_004246710.1| PREDICTED: serine/threonine-protein kinase P...   160   2e-37
ref|NP_001237717.1| protein kinase-like protein [Glycine max] gi...   158   7e-37
ref|XP_003542489.1| PREDICTED: serine/threonine-protein kinase P...   158   9e-37
emb|CAB86034.1| protein kinase-like [Arabidopsis thaliana]            157   1e-36
ref|XP_006828265.1| hypothetical protein AMTR_s00023p00210090 [A...   157   2e-36
ref|NP_195900.2| protein CDG1-LIKE 1 [Arabidopsis thaliana] gi|1...   157   2e-36
ref|XP_002873066.1| kinase family protein [Arabidopsis lyrata su...   157   2e-36
ref|XP_006398733.1| hypothetical protein EUTSA_v10013827mg [Eutr...   156   3e-36
ref|XP_006287938.1| hypothetical protein CARUB_v10001173mg [Caps...   155   4e-36
ref|XP_007162707.1| hypothetical protein PHAVU_001G173600g [Phas...   155   8e-36
gb|ACJ85744.1| unknown [Medicago truncatula] gi|388509798|gb|AFK...   155   8e-36
ref|XP_002281418.1| PREDICTED: serine/threonine-protein kinase P...   155   8e-36
gb|AAQ96340.1| protein kinase-like protein [Vitis aestivalis]         155   8e-36

>ref|XP_007027193.1| Kinase superfamily protein isoform 1 [Theobroma cacao]
           gi|508715798|gb|EOY07695.1| Kinase superfamily protein
           isoform 1 [Theobroma cacao]
          Length = 394

 Score =  179 bits (455), Expect = 3e-43
 Identities = 91/131 (69%), Positives = 102/131 (77%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DR+KFSQMADPMLQGQYP RGL+QALA+AAMCVQE+P MRPLIADVVT
Sbjct: 282 QNLVAWARPLFKDRKKFSQMADPMLQGQYPPRGLFQALAVAAMCVQEQPNMRPLIADVVT 341

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKRDSNKKLDGXXXXXXXPRTKRDYNKKLNG 177
            L++LASQK++PDTQ VQ SR+AP TPPRTKRD                     +KK NG
Sbjct: 342 ALTYLASQKFEPDTQSVQGSRLAPGTPPRTKRDR--------------------DKKPNG 381

Query: 176 GSGSERDRTRR 144
           GSGSERDRTRR
Sbjct: 382 GSGSERDRTRR 392


>ref|XP_007205320.1| hypothetical protein PRUPE_ppa006902mg [Prunus persica]
           gi|462400962|gb|EMJ06519.1| hypothetical protein
           PRUPE_ppa006902mg [Prunus persica]
          Length = 391

 Score =  167 bits (424), Expect = 1e-39
 Identities = 78/97 (80%), Positives = 90/97 (92%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DR+KFSQMADPMLQGQYP RGLYQALA+AAMCVQE+P MRP+IADVVT
Sbjct: 291 QNLVAWARPLFKDRKKFSQMADPMLQGQYPQRGLYQALAVAAMCVQEQPNMRPVIADVVT 350

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKRDSNKK 246
            L++LASQK+D +TQPVQ+SR+AP TPPRTKRDS +K
Sbjct: 351 ALTYLASQKHDQETQPVQSSRLAPCTPPRTKRDSERK 387


>ref|XP_002276042.1| PREDICTED: serine/threonine-protein kinase PBS1 [Vitis vinifera]
           gi|297741502|emb|CBI32634.3| unnamed protein product
           [Vitis vinifera]
          Length = 396

 Score =  167 bits (424), Expect = 1e-39
 Identities = 82/130 (63%), Positives = 98/130 (75%)
 Frame = -1

Query: 533 NLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVTG 354
           NLVAWA+PLF DRRKF  MADPMLQGQYP+RGLYQALA+AAMCVQE+P +RPLI DVVT 
Sbjct: 285 NLVAWARPLFKDRRKFLHMADPMLQGQYPLRGLYQALAVAAMCVQEQPNLRPLIVDVVTA 344

Query: 353 LSFLASQKYDPDTQPVQTSRMAPSTPPRTKRDSNKKLDGXXXXXXXPRTKRDYNKKLNGG 174
           L++LA+Q YDPDTQPVQ+SR+APSTPPR K+D ++KL                       
Sbjct: 345 LTYLAAQTYDPDTQPVQSSRVAPSTPPRAKKDGDRKLP--------------------SS 384

Query: 173 SGSERDRTRR 144
           +GS++DRTRR
Sbjct: 385 AGSQKDRTRR 394


>gb|EXB84828.1| Serine/threonine-protein kinase PBS1 [Morus notabilis]
          Length = 380

 Score =  163 bits (412), Expect = 3e-38
 Identities = 78/93 (83%), Positives = 86/93 (92%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLFNDRRKFSQMADPMLQGQYP RGLYQALA+AAMCVQE+P MRP+IADVVT
Sbjct: 288 QNLVAWARPLFNDRRKFSQMADPMLQGQYPARGLYQALAVAAMCVQEQPNMRPVIADVVT 347

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKRD 258
            LS+LASQKYDPDTQPVQ+ R AP T P+T+RD
Sbjct: 348 ALSYLASQKYDPDTQPVQSFRFAPGT-PKTRRD 379


>gb|AGU91423.1| serine/threonine-protein kinase PBS1, partial [Chrysanthemum
           boreale]
          Length = 371

 Score =  162 bits (411), Expect = 4e-38
 Identities = 73/97 (75%), Positives = 89/97 (91%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKF Q+ADP+LQGQYP RGLYQALA+AAMCVQE+P MRP+IADVVT
Sbjct: 275 QNLVAWARPLFKDRRKFCQIADPLLQGQYPSRGLYQALAVAAMCVQEQPNMRPVIADVVT 334

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKRDSNKK 246
            LS+LASQKYDP+T P+Q +R +P+TPPR+KRD++K+
Sbjct: 335 ALSYLASQKYDPETHPIQNARWSPTTPPRSKRDNDKR 371


>ref|XP_006367263.1| PREDICTED: serine/threonine-protein kinase PBS1-like [Solanum
           tuberosum]
          Length = 390

 Score =  161 bits (407), Expect = 1e-37
 Identities = 76/99 (76%), Positives = 87/99 (87%)
 Frame = -1

Query: 533 NLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVTG 354
           NLVAWAKPLF DRRKFSQMADPMLQGQYP RGLYQALA+AAMCVQE+P MRP+IADVVT 
Sbjct: 285 NLVAWAKPLFRDRRKFSQMADPMLQGQYPERGLYQALAVAAMCVQEQPNMRPVIADVVTA 344

Query: 353 LSFLASQKYDPDTQPVQTSRMAPSTPPRTKRDSNKKLDG 237
           LS+LA+QK+D DTQ VQ  R  P+TPPRT+RD++K+  G
Sbjct: 345 LSYLAAQKFDSDTQGVQNLRWTPATPPRTRRDADKRQKG 383


>ref|XP_007144514.1| hypothetical protein PHAVU_007G162300g [Phaseolus vulgaris]
           gi|561017704|gb|ESW16508.1| hypothetical protein
           PHAVU_007G162300g [Phaseolus vulgaris]
          Length = 382

 Score =  160 bits (405), Expect = 2e-37
 Identities = 77/92 (83%), Positives = 83/92 (90%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKFSQMADPMLQGQYP RGLYQALA+AAMCVQE+  MRP+IADVVT
Sbjct: 290 QNLVAWARPLFKDRRKFSQMADPMLQGQYPSRGLYQALAVAAMCVQEQANMRPVIADVVT 349

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKR 261
            LS+LASQKYDP TQ VQ+SR AP TPPRTKR
Sbjct: 350 ALSYLASQKYDPSTQTVQSSRHAPGTPPRTKR 381


>ref|XP_004246710.1| PREDICTED: serine/threonine-protein kinase PBS1-like [Solanum
           lycopersicum]
          Length = 391

 Score =  160 bits (405), Expect = 2e-37
 Identities = 75/99 (75%), Positives = 87/99 (87%)
 Frame = -1

Query: 533 NLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVTG 354
           NLVAWAKPLF DRRKFSQMADPMLQGQYP RGLYQALA+AAMCVQE+P MRP+IADVVT 
Sbjct: 286 NLVAWAKPLFRDRRKFSQMADPMLQGQYPERGLYQALAVAAMCVQEQPNMRPVIADVVTA 345

Query: 353 LSFLASQKYDPDTQPVQTSRMAPSTPPRTKRDSNKKLDG 237
           LS+LA+QK+D DT+ VQ  R  P+TPPRT+RD++K+  G
Sbjct: 346 LSYLAAQKFDSDTEGVQNPRWTPATPPRTRRDADKRQKG 384


>ref|NP_001237717.1| protein kinase-like protein [Glycine max]
           gi|223452496|gb|ACM89575.1| protein kinase-like protein
           [Glycine max]
          Length = 383

 Score =  158 bits (400), Expect = 7e-37
 Identities = 75/92 (81%), Positives = 84/92 (91%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKFSQMADPMLQGQYP RGLYQALA+AAMCVQE+  MRP+IADVVT
Sbjct: 290 QNLVAWARPLFKDRRKFSQMADPMLQGQYPSRGLYQALAVAAMCVQEQANMRPVIADVVT 349

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKR 261
            LS+LA QKYDP+TQ VQ+SR+AP TPPR+KR
Sbjct: 350 ALSYLALQKYDPNTQTVQSSRLAPGTPPRSKR 381


>ref|XP_003542489.1| PREDICTED: serine/threonine-protein kinase PBS1-like [Glycine max]
          Length = 383

 Score =  158 bits (399), Expect = 9e-37
 Identities = 74/92 (80%), Positives = 85/92 (92%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKFSQMADPMLQGQYP RGL+QALA+AAMCVQE+  MRP+IADVVT
Sbjct: 290 QNLVAWARPLFKDRRKFSQMADPMLQGQYPPRGLFQALAVAAMCVQEQANMRPVIADVVT 349

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKR 261
            LS+LASQKYDP+TQ +Q+SR+AP TPPR+KR
Sbjct: 350 ALSYLASQKYDPNTQTLQSSRLAPGTPPRSKR 381


>emb|CAB86034.1| protein kinase-like [Arabidopsis thaliana]
          Length = 395

 Score =  157 bits (398), Expect = 1e-36
 Identities = 75/93 (80%), Positives = 83/93 (89%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKFSQMADPMLQGQYP RGLYQALA+AAMCVQE+P +RPLIADVVT
Sbjct: 286 QNLVAWARPLFKDRRKFSQMADPMLQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVT 345

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKRD 258
            LS+LASQK+DP  QPVQ S  AP TPPR+KR+
Sbjct: 346 ALSYLASQKFDPLAQPVQGSLFAPGTPPRSKRE 378


>ref|XP_006828265.1| hypothetical protein AMTR_s00023p00210090 [Amborella trichopoda]
           gi|548832912|gb|ERM95681.1| hypothetical protein
           AMTR_s00023p00210090 [Amborella trichopoda]
          Length = 402

 Score =  157 bits (396), Expect = 2e-36
 Identities = 74/97 (76%), Positives = 88/97 (90%), Gaps = 1/97 (1%)
 Frame = -1

Query: 533 NLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVTG 354
           NLVAWA+PLF DRRKFSQMADP LQGQ+P+RGLYQALA+AAMCVQE+PTMRPLIADVVT 
Sbjct: 283 NLVAWARPLFKDRRKFSQMADPTLQGQFPMRGLYQALAVAAMCVQEQPTMRPLIADVVTA 342

Query: 353 LSFLASQKYDPDTQPVQ-TSRMAPSTPPRTKRDSNKK 246
           L++LASQ YDP+  PVQ +SR+AP+TPPR +RD+ +K
Sbjct: 343 LTYLASQTYDPEAHPVQSSSRLAPATPPRARRDTMEK 379


>ref|NP_195900.2| protein CDG1-LIKE 1 [Arabidopsis thaliana]
           gi|110736288|dbj|BAF00114.1| protein kinase like protein
           [Arabidopsis thaliana] gi|332003136|gb|AED90519.1|
           protein kinase family protein [Arabidopsis thaliana]
          Length = 378

 Score =  157 bits (396), Expect = 2e-36
 Identities = 75/92 (81%), Positives = 82/92 (89%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKFSQMADPMLQGQYP RGLYQALA+AAMCVQE+P +RPLIADVVT
Sbjct: 286 QNLVAWARPLFKDRRKFSQMADPMLQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVT 345

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKR 261
            LS+LASQK+DP  QPVQ S  AP TPPR+KR
Sbjct: 346 ALSYLASQKFDPLAQPVQGSLFAPGTPPRSKR 377


>ref|XP_002873066.1| kinase family protein [Arabidopsis lyrata subsp. lyrata]
           gi|297318903|gb|EFH49325.1| kinase family protein
           [Arabidopsis lyrata subsp. lyrata]
          Length = 378

 Score =  157 bits (396), Expect = 2e-36
 Identities = 75/92 (81%), Positives = 82/92 (89%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKFSQMADPMLQGQYP RGLYQALA+AAMCVQE+P +RPLIADVVT
Sbjct: 286 QNLVAWARPLFKDRRKFSQMADPMLQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVT 345

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKR 261
            LS+LASQK+DP  QPVQ S  AP TPPR+KR
Sbjct: 346 ALSYLASQKFDPLAQPVQGSLFAPGTPPRSKR 377


>ref|XP_006398733.1| hypothetical protein EUTSA_v10013827mg [Eutrema salsugineum]
           gi|557099823|gb|ESQ40186.1| hypothetical protein
           EUTSA_v10013827mg [Eutrema salsugineum]
          Length = 378

 Score =  156 bits (394), Expect = 3e-36
 Identities = 73/92 (79%), Positives = 82/92 (89%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKFSQMADPM+QGQYP RGLYQALA+AAMCVQE+P +RPLIADVVT
Sbjct: 286 QNLVAWARPLFKDRRKFSQMADPMIQGQYPPRGLYQALAVAAMCVQEQPNLRPLIADVVT 345

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKR 261
            L++LASQK+DP  QPVQ S  AP TPPR+KR
Sbjct: 346 ALTYLASQKFDPMAQPVQASLFAPGTPPRSKR 377


>ref|XP_006287938.1| hypothetical protein CARUB_v10001173mg [Capsella rubella]
           gi|482556644|gb|EOA20836.1| hypothetical protein
           CARUB_v10001173mg [Capsella rubella]
          Length = 381

 Score =  155 bits (393), Expect = 4e-36
 Identities = 74/92 (80%), Positives = 81/92 (88%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKFSQMADPMLQGQYP RGLYQALA+ AMCVQE+P +RPLIADVVT
Sbjct: 289 QNLVAWARPLFKDRRKFSQMADPMLQGQYPPRGLYQALAVGAMCVQEQPNLRPLIADVVT 348

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKR 261
            LS+LASQK+DP  QPVQ S  AP TPPR+KR
Sbjct: 349 ALSYLASQKFDPMAQPVQGSLFAPGTPPRSKR 380


>ref|XP_007162707.1| hypothetical protein PHAVU_001G173600g [Phaseolus vulgaris]
           gi|561036171|gb|ESW34701.1| hypothetical protein
           PHAVU_001G173600g [Phaseolus vulgaris]
          Length = 355

 Score =  155 bits (391), Expect = 8e-36
 Identities = 73/92 (79%), Positives = 81/92 (88%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKFSQMADP LQGQYP RGLYQALA+AAMCVQE+  MRP+IADVVT
Sbjct: 262 QNLVAWARPLFRDRRKFSQMADPTLQGQYPPRGLYQALAVAAMCVQEQANMRPVIADVVT 321

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKR 261
            LS+LA QKYDP+T  VQ SR+AP TPPRT+R
Sbjct: 322 ALSYLAKQKYDPNTHTVQNSRLAPGTPPRTRR 353


>gb|ACJ85744.1| unknown [Medicago truncatula] gi|388509798|gb|AFK42965.1| unknown
           [Medicago truncatula]
          Length = 417

 Score =  155 bits (391), Expect = 8e-36
 Identities = 71/92 (77%), Positives = 84/92 (91%)
 Frame = -1

Query: 536 QNLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVT 357
           QNLVAWA+PLF DRRKF+QMADPMLQGQYP RG+YQALA+AAMCVQE+  MRP+IADVVT
Sbjct: 287 QNLVAWARPLFKDRRKFTQMADPMLQGQYPSRGIYQALAVAAMCVQEQANMRPVIADVVT 346

Query: 356 GLSFLASQKYDPDTQPVQTSRMAPSTPPRTKR 261
            LS+LASQ+Y+P+TQ VQ+SR+ P TPPRT+R
Sbjct: 347 ALSYLASQRYEPNTQTVQSSRLGPGTPPRTRR 378


>ref|XP_002281418.1| PREDICTED: serine/threonine-protein kinase PBS1 [Vitis vinifera]
           gi|297736456|emb|CBI25327.3| unnamed protein product
           [Vitis vinifera]
          Length = 376

 Score =  155 bits (391), Expect = 8e-36
 Identities = 74/92 (80%), Positives = 85/92 (92%)
 Frame = -1

Query: 533 NLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVTG 354
           NLVAWA+PLF DRRKFSQMADPML GQYP+RGLYQALA+AAMCVQE+P MRPLIADVVT 
Sbjct: 285 NLVAWARPLFKDRRKFSQMADPMLHGQYPLRGLYQALAVAAMCVQEQPNMRPLIADVVTA 344

Query: 353 LSFLASQKYDPDTQPVQTSRMAPSTPPRTKRD 258
           L++LASQKYDP+TQPVQ+SRM  ST PR++R+
Sbjct: 345 LTYLASQKYDPETQPVQSSRMGSST-PRSRRE 375


>gb|AAQ96340.1| protein kinase-like protein [Vitis aestivalis]
          Length = 376

 Score =  155 bits (391), Expect = 8e-36
 Identities = 74/92 (80%), Positives = 85/92 (92%)
 Frame = -1

Query: 533 NLVAWAKPLFNDRRKFSQMADPMLQGQYPVRGLYQALAIAAMCVQEEPTMRPLIADVVTG 354
           NLVAWA+PLF DRRKFSQMADPML GQYP+RGLYQALA+AAMCVQE+P MRPLIADVVT 
Sbjct: 285 NLVAWARPLFKDRRKFSQMADPMLHGQYPLRGLYQALAVAAMCVQEQPNMRPLIADVVTA 344

Query: 353 LSFLASQKYDPDTQPVQTSRMAPSTPPRTKRD 258
           L++LASQKYDP+TQPVQ+SRM  ST PR++R+
Sbjct: 345 LTYLASQKYDPETQPVQSSRMGSST-PRSRRE 375