BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Paeonia22_contig00004371
         (1859 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]               639   e-180
ref|XP_002300344.1| DNA topoisomerase family protein [Populus tr...   620   e-175
ref|XP_007020666.1| DNA topoisomerase I alpha isoform 3 [Theobro...   619   e-174
ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobro...   619   e-174
ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform ...   617   e-174
ref|XP_006452480.1| hypothetical protein CICLE_v10007398mg [Citr...   613   e-172
ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citr...   613   e-172
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                 610   e-172
ref|XP_002317355.1| DNA topoisomerase family protein [Populus tr...   601   e-169
ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis v...   595   e-167
ref|XP_002529020.1| DNA topoisomerase type I, putative [Ricinus ...   595   e-167
ref|XP_007020667.1| DNA topoisomerase I alpha isoform 4, partial...   595   e-167
ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinife...   592   e-166
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...   592   e-166
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]             591   e-166
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]       589   e-165
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]                587   e-165
gb|AAD08711.1| topoisomerase I [Nicotiana tabacum] gi|14626487|g...   585   e-164
gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Mimulus...   581   e-163
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]             581   e-163

>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score =  639 bits (1649), Expect = e-180
 Identities = 349/586 (59%), Positives = 398/586 (67%), Gaps = 4/586 (0%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSKGLPSSANQLNHSSKQNS-SIVKEEKHSVKHXX 1572
            +KS  ASP+ S+  A ASPV    AN K   SS ++  HSSKQN+ ++VKEEK  V    
Sbjct: 79   MKSPIASPKASTSFAKASPV----ANPKVSSSSDDRSKHSSKQNTINVVKEEKELVN--- 131

Query: 1571 XXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDD 1392
                         PLS R+  GL+KGS+N+ANKGL  ++P      KP IN  +++SDD 
Sbjct: 132  PAAEPYGDSEDEKPLSARLFTGLTKGSSNNANKGLINSSPASLPVPKPEINRYSDDSDD- 190

Query: 1391 DEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDDQRKSTPVFNKRPLDX 1215
             E+PLSS+F                D+ K + S  QQNGS  R    KS+   NKRPL  
Sbjct: 191  -EIPLSSKFRLKANAGTSTVKSYESDDNKTLVSNFQQNGSINRGS--KSSIKVNKRPLGE 247

Query: 1214 XXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAED--DDHVPIAQRIKKSASSDGKSLS 1041
                        KLS AS P+ N Q S KAEPKA+D  DDHVPI+QR+KKSA+S  KS +
Sbjct: 248  VKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKADDSDDDHVPISQRMKKSATSGNKSST 307

Query: 1040 ANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQKWTTLVHNGVIFPPPYK 861
            A QK                             K+ PSSGEG+KW TLVHNGVIFPPPYK
Sbjct: 308  AKQKVTKVVSSSMKKASKKFKKVVKKSKYSKSSKVPPSSGEGKKWNTLVHNGVIFPPPYK 367

Query: 860  PHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQK 681
            PHGVKMLYKGKPVDLTPEQEEVATMFAVM+DTDY  K KF ENFM DW+KILGKNH+IQ 
Sbjct: 368  PHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMTKSKFKENFMDDWRKILGKNHVIQN 427

Query: 680  FEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRVE 501
             EDCDF PIYEWHQ                            MWA+++GVKEKVGNFRVE
Sbjct: 428  LEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEERLKQEEKYMWAIVNGVKEKVGNFRVE 487

Query: 500  PPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLAF 321
            PP LFRGRGEHPKMGKLK+ IRPSDITINIGK APIPECPIPGE W+E+RHDNTVTWLAF
Sbjct: 488  PPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIPECPIPGESWKEIRHDNTVTWLAF 547

Query: 320  WNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKRQ 141
            WNDPI P+EFKYVFLAASSSLKGQSDKEKYEK+R LK++I+GIR AYT+DF +KD+TKRQ
Sbjct: 548  WNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLKDFIQGIRAAYTKDFASKDITKRQ 607

Query: 140  IAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            IAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV   PP+ L+
Sbjct: 608  IAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPKPPSILK 653


>ref|XP_002300344.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222847602|gb|EEE85149.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 877

 Score =  620 bits (1598), Expect = e-175
 Identities = 339/585 (57%), Positives = 391/585 (66%), Gaps = 3/585 (0%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSKGLPSSANQLNHSSKQN-SSIVKEEKHSVKHXX 1572
            +KSST SP+ S+ SA ASP+KS L  ++ L SS +QL  +SKQ  S+ VKEE  S+    
Sbjct: 76   MKSSTGSPKASASSAKASPLKSPLTYTRALTSSNDQLKQASKQVVSNAVKEETKSI---- 131

Query: 1571 XXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDD 1392
                         PLS RI     KGS N+ NKG++              ++K+E SDDD
Sbjct: 132  ---VDDEDSEDDKPLSSRI-----KGSTNNVNKGVTAP-----------AHVKDEPSDDD 172

Query: 1391 DEMPLSSRFXXXXXXXXXXXXXXSD-EKKPMASKLQQNGSTMRDDQRKSTPVFNKRPLDX 1215
             E+PLSSRF                 E +P  SK Q NGST  D Q+KS+ V  KRP+D 
Sbjct: 173  -EVPLSSRFAMKSNAGTSSSKSIRSSEIRPFPSKSQLNGSTKNDKQQKSSVVPTKRPMDN 231

Query: 1214 XXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDDHVPIAQRIKKSASSDGKSLSAN 1035
                        KL  A    K  QV++K E KA+DDDH+ I+QR+KK+ SS  KS  A 
Sbjct: 232  KVPSNHSSAKKPKLLDACTTTKVKQVTVKVEQKADDDDHLTISQRMKKADSSANKSSFAK 291

Query: 1034 QKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQK-WTTLVHNGVIFPPPYKP 858
            +K                             K+QP S +GQK WTTLVHNGVIFPPPYKP
Sbjct: 292  KKVTKVVSSSLKKTTQKNKKQMKNSKYSKSTKVQPGSSDGQKKWTTLVHNGVIFPPPYKP 351

Query: 857  HGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQKF 678
            HGVK+LYKGKP+DLTPEQEEVATMFAVM DTDY +K +F +NF  DW+K+LGKNH+IQK 
Sbjct: 352  HGVKILYKGKPIDLTPEQEEVATMFAVMKDTDYVQKPQFRQNFWNDWRKLLGKNHVIQKL 411

Query: 677  EDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRVEP 498
            +DCDF PIYEWHQ                            MWA+++GVKEKVGNFRVEP
Sbjct: 412  DDCDFNPIYEWHQQEKEKKKQMSTEEKKVLKEEKLKQEEKYMWAIVNGVKEKVGNFRVEP 471

Query: 497  PGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLAFW 318
            PGLFRGRGEHPKMGKLK RIRPSDITINIGK APIPECPIPGERW+EV+HDNTVTWLAFW
Sbjct: 472  PGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAFW 531

Query: 317  NDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKRQI 138
            NDPINPKEFKYVFLAASSSLKGQSDKEKYEK+R LK+YI  IR AYT+DF +KD+TKRQI
Sbjct: 532  NDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIRAAYTKDFASKDITKRQI 591

Query: 137  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            AVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV  +PPNKL+
Sbjct: 592  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPPNKLK 636


>ref|XP_007020666.1| DNA topoisomerase I alpha isoform 3 [Theobroma cacao]
            gi|590606159|ref|XP_007020668.1| DNA topoisomerase I
            alpha isoform 3 [Theobroma cacao]
            gi|508720294|gb|EOY12191.1| DNA topoisomerase I alpha
            isoform 3 [Theobroma cacao] gi|508720296|gb|EOY12193.1|
            DNA topoisomerase I alpha isoform 3 [Theobroma cacao]
          Length = 836

 Score =  619 bits (1597), Expect = e-174
 Identities = 333/585 (56%), Positives = 382/585 (65%), Gaps = 3/585 (0%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSKGLPSSANQLNHSSKQN-SSIVKEEKHSVKHXX 1572
            VKS   SP+ S+ S  A PVKS + N K   S  +Q   + KQN ++ VKE +  +K   
Sbjct: 84   VKSPILSPKASTSSTKALPVKSPVVNFKASTSLNDQSKQALKQNMTTAVKEGRSPIKGTT 143

Query: 1571 XXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDD 1392
                         PLS R+     KG +N  NKG ST+ P  S+   P   +K    D D
Sbjct: 144  EPNSDDDDDDDSLPLSARL-----KGISNQGNKGASTSAPAQSRRLVPKTEVKVSAEDPD 198

Query: 1391 DEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDDQRKSTPVFNKRPLDX 1215
            DE PLS+RF                DEKKP+ASK+QQNGS M+  Q+ S+ +  KRPLD 
Sbjct: 199  DEAPLSARFNVKSNTGTSSSRLHDCDEKKPLASKIQQNGSIMKGKQQNSSTLSGKRPLDK 258

Query: 1214 XXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDDHVPIAQRIKKSASSDGKSLSAN 1035
                        K S A   +K  QV++KAE   EDDDH+PIAQR+KKS +S+ K  S  
Sbjct: 259  GNSSDHSSAKKPKTSDAPTTMKTKQVTVKAEKADEDDDHMPIAQRMKKSTASNSKLSSMK 318

Query: 1034 QKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQK-WTTLVHNGVIFPPPYKP 858
            QK                             K+ PSSG+GQK W+TLVHNGVIFP PY P
Sbjct: 319  QKTTKVVSSSFKKINKKSKKEMKSSKYIKSTKVPPSSGDGQKKWSTLVHNGVIFPSPYTP 378

Query: 857  HGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQKF 678
            HGVKMLY G+PVDLTPEQEEVATMFAVM DTDY  K +F +NF  DW K+LGKNH I+  
Sbjct: 379  HGVKMLYDGRPVDLTPEQEEVATMFAVMKDTDYMSKTQFKKNFWEDWSKLLGKNHTIKDL 438

Query: 677  EDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRVEP 498
            + CDF PIYEWH                             MWA++DGVKEKVGNFRVEP
Sbjct: 439  DRCDFTPIYEWHLQEKEKKKQMSSEEKKALKEEKLKQEEKFMWAIVDGVKEKVGNFRVEP 498

Query: 497  PGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLAFW 318
            PGLFRGRGEHPKMGKLKRRIRPSDITINIGK APIPECPIPGERW++++HDNTVTWLAFW
Sbjct: 499  PGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGERWKDIKHDNTVTWLAFW 558

Query: 317  NDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKRQI 138
            NDPINPKEFKYVFLAASSSLKGQSDKEKYEK+R LK+YI+ IR AYT+DFT KDV KRQI
Sbjct: 559  NDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRAAYTKDFTTKDVMKRQI 618

Query: 137  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            AVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV  +PPNKL+
Sbjct: 619  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLK 663


>ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
            gi|590606147|ref|XP_007020665.1| DNA topoisomerase I
            alpha isoform 1 [Theobroma cacao]
            gi|508720292|gb|EOY12189.1| DNA topoisomerase I alpha
            isoform 1 [Theobroma cacao] gi|508720293|gb|EOY12190.1|
            DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
          Length = 904

 Score =  619 bits (1597), Expect = e-174
 Identities = 333/585 (56%), Positives = 382/585 (65%), Gaps = 3/585 (0%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSKGLPSSANQLNHSSKQN-SSIVKEEKHSVKHXX 1572
            VKS   SP+ S+ S  A PVKS + N K   S  +Q   + KQN ++ VKE +  +K   
Sbjct: 84   VKSPILSPKASTSSTKALPVKSPVVNFKASTSLNDQSKQALKQNMTTAVKEGRSPIKGTT 143

Query: 1571 XXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDD 1392
                         PLS R+     KG +N  NKG ST+ P  S+   P   +K    D D
Sbjct: 144  EPNSDDDDDDDSLPLSARL-----KGISNQGNKGASTSAPAQSRRLVPKTEVKVSAEDPD 198

Query: 1391 DEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDDQRKSTPVFNKRPLDX 1215
            DE PLS+RF                DEKKP+ASK+QQNGS M+  Q+ S+ +  KRPLD 
Sbjct: 199  DEAPLSARFNVKSNTGTSSSRLHDCDEKKPLASKIQQNGSIMKGKQQNSSTLSGKRPLDK 258

Query: 1214 XXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDDHVPIAQRIKKSASSDGKSLSAN 1035
                        K S A   +K  QV++KAE   EDDDH+PIAQR+KKS +S+ K  S  
Sbjct: 259  GNSSDHSSAKKPKTSDAPTTMKTKQVTVKAEKADEDDDHMPIAQRMKKSTASNSKLSSMK 318

Query: 1034 QKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQK-WTTLVHNGVIFPPPYKP 858
            QK                             K+ PSSG+GQK W+TLVHNGVIFP PY P
Sbjct: 319  QKTTKVVSSSFKKINKKSKKEMKSSKYIKSTKVPPSSGDGQKKWSTLVHNGVIFPSPYTP 378

Query: 857  HGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQKF 678
            HGVKMLY G+PVDLTPEQEEVATMFAVM DTDY  K +F +NF  DW K+LGKNH I+  
Sbjct: 379  HGVKMLYDGRPVDLTPEQEEVATMFAVMKDTDYMSKTQFKKNFWEDWSKLLGKNHTIKDL 438

Query: 677  EDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRVEP 498
            + CDF PIYEWH                             MWA++DGVKEKVGNFRVEP
Sbjct: 439  DRCDFTPIYEWHLQEKEKKKQMSSEEKKALKEEKLKQEEKFMWAIVDGVKEKVGNFRVEP 498

Query: 497  PGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLAFW 318
            PGLFRGRGEHPKMGKLKRRIRPSDITINIGK APIPECPIPGERW++++HDNTVTWLAFW
Sbjct: 499  PGLFRGRGEHPKMGKLKRRIRPSDITINIGKDAPIPECPIPGERWKDIKHDNTVTWLAFW 558

Query: 317  NDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKRQI 138
            NDPINPKEFKYVFLAASSSLKGQSDKEKYEK+R LK+YI+ IR AYT+DFT KDV KRQI
Sbjct: 559  NDPINPKEFKYVFLAASSSLKGQSDKEKYEKARMLKDYIKNIRAAYTKDFTTKDVMKRQI 618

Query: 137  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            AVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV  +PPNKL+
Sbjct: 619  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLK 663


>ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform X1 [Citrus sinensis]
            gi|568842074|ref|XP_006474978.1| PREDICTED: DNA
            topoisomerase 1-like isoform X2 [Citrus sinensis]
            gi|568842076|ref|XP_006474979.1| PREDICTED: DNA
            topoisomerase 1-like isoform X3 [Citrus sinensis]
            gi|568842078|ref|XP_006474980.1| PREDICTED: DNA
            topoisomerase 1-like isoform X4 [Citrus sinensis]
          Length = 902

 Score =  617 bits (1592), Expect = e-174
 Identities = 331/587 (56%), Positives = 395/587 (67%), Gaps = 7/587 (1%)
 Frame = -1

Query: 1742 SSTASPEVSSL-----SANASPVKSSLANSKGLPSSANQLNHSSKQNS-SIVKEEKHSVK 1581
            S+ ASP  S +     S   SPVKS +ANSK      ++L  S + N+ ++VK+E+  +K
Sbjct: 84   SAKASPSKSPMRSPVKSPVRSPVKSPVANSKESSPLDDRLKQSPQHNALAVVKKEE--IK 141

Query: 1580 HXXXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEES 1401
                            PLS R+     KG++ + N+G+  +    + S+   +N+K +  
Sbjct: 142  DGNGLKSDDNDSEDDKPLSARL-----KGNSKNVNQGIGASKADAAISE---VNVKTDPE 193

Query: 1400 DDDDEMPLSSRFXXXXXXXXXXXXXXSDEKKPMASKLQQNGSTMRDDQRKSTPVFNKRPL 1221
            D DDE+PLSSRF              SDEKKP+ASK+QQNGST R+ Q+KS+ V  KRPL
Sbjct: 194  DSDDEVPLSSRFPKSNAGTSGAKPIDSDEKKPLASKVQQNGSTSRETQQKSSSVPVKRPL 253

Query: 1220 DXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDDHVPIAQRIKKSASSDGKSLS 1041
                          K+S  S+ +K  QV++K E KA+DDDH+PI+QR+K SA S  KS++
Sbjct: 254  QKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKKADDDDHIPISQRMKNSAPSVKKSVT 313

Query: 1040 ANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQK-WTTLVHNGVIFPPPY 864
               KA                            KM P SG+GQK WTTLVHNGVIFPPPY
Sbjct: 314  NTAKATKSVSSSSNKINKKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTLVHNGVIFPPPY 373

Query: 863  KPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQ 684
             PHGVKMLYKGK V+LTPEQEEVATMFAVM+DTDY +K KF ENF  DW+K+LGKNH+IQ
Sbjct: 374  LPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLLGKNHVIQ 433

Query: 683  KFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRV 504
              E CDF+PIY+WHQ                            MWA++DGVKEKVGNFRV
Sbjct: 434  NLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEKLKQEEKYMWAIVDGVKEKVGNFRV 493

Query: 503  EPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLA 324
            EPPGLFRGRGEHPKMGKLK+RI+PSDITINIGK  PIPECPIPGE W+EV+HDNTVTWLA
Sbjct: 494  EPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVPIPECPIPGESWKEVKHDNTVTWLA 553

Query: 323  FWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKR 144
            FWNDPINPKEFKYVFLAASSSLKGQSDKEKYEK+R LK+YI  IR AYT+DF ++D T+R
Sbjct: 554  FWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHSIRAAYTKDFVSRDGTRR 613

Query: 143  QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV  +PPNKL+
Sbjct: 614  QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLK 660


>ref|XP_006452480.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|557555706|gb|ESR65720.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 824

 Score =  613 bits (1580), Expect = e-172
 Identities = 329/592 (55%), Positives = 395/592 (66%), Gaps = 11/592 (1%)
 Frame = -1

Query: 1745 KSSTASPEVSSL---------SANASPVKSSLANSKGLPSSANQLNHSSKQNS-SIVKEE 1596
            K++T+S + S L         S   SPVKS +ANSK      ++L    + N+ ++VK+E
Sbjct: 79   KATTSSAKASPLKSPMRSPVKSPVRSPVKSPVANSKESSPLDDRLKQLPQHNALAVVKKE 138

Query: 1595 KHSVKHXXXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINI 1416
            +  +K                PLS R+     KG+  + N+G+  +    + S+   +N+
Sbjct: 139  E--IKDGNGLKSDDNDSEDDKPLSARL-----KGNTKNVNQGIGASKADAAISE---VNV 188

Query: 1415 KNEESDDDDEMPLSSRFXXXXXXXXXXXXXXSDEKKPMASKLQQNGSTMRDDQRKSTPVF 1236
            K +  D DDE+PLSSRF              SDEKKP+ASK+QQNGST R+ Q+KS+ V 
Sbjct: 189  KTDPEDSDDEVPLSSRFPKSNAGTSGAKPIDSDEKKPLASKVQQNGSTSRETQQKSSSVP 248

Query: 1235 NKRPLDXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDDHVPIAQRIKKSASSD 1056
             KRPL              K+S  S+ +K  QV++K E KA+DDDH+PI+QR+K SA S 
Sbjct: 249  VKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKKADDDDHIPISQRMKNSAPSV 308

Query: 1055 GKSLSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQK-WTTLVHNGVI 879
             KS++   KA                            KM P SG+GQK WTTLVHNGVI
Sbjct: 309  KKSVTNTAKATKSVSSSSKKINKKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTLVHNGVI 368

Query: 878  FPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGK 699
            FPPPY PHGVKMLYKGK V+LTPEQEEVATMFAVM+DTDY +K KF ENF  DW+K+LGK
Sbjct: 369  FPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLLGK 428

Query: 698  NHIIQKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKV 519
            NH+IQ  E CDF+PIY+WHQ                            MWA++DGVKEKV
Sbjct: 429  NHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEKLKQEEKYMWAIVDGVKEKV 488

Query: 518  GNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNT 339
            GNFRVEPPGLFRGRGEHPKMGKLK+RI+PSDITINIGK  PIPECPIPGE W+EV+HDNT
Sbjct: 489  GNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVPIPECPIPGESWKEVKHDNT 548

Query: 338  VTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNK 159
            VTWLAFWNDPINPKEFKYVFLAASSSLKGQSD+EKYEK+R LK+YI  IR AYT+DF ++
Sbjct: 549  VTWLAFWNDPINPKEFKYVFLAASSSLKGQSDREKYEKARKLKDYIHSIRAAYTKDFVSR 608

Query: 158  DVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            D T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV  +PPNKL+
Sbjct: 609  DGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLK 660


>ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|567920950|ref|XP_006452481.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555705|gb|ESR65719.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555707|gb|ESR65721.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 902

 Score =  613 bits (1580), Expect = e-172
 Identities = 329/592 (55%), Positives = 395/592 (66%), Gaps = 11/592 (1%)
 Frame = -1

Query: 1745 KSSTASPEVSSL---------SANASPVKSSLANSKGLPSSANQLNHSSKQNS-SIVKEE 1596
            K++T+S + S L         S   SPVKS +ANSK      ++L    + N+ ++VK+E
Sbjct: 79   KATTSSAKASPLKSPMRSPVKSPVRSPVKSPVANSKESSPLDDRLKQLPQHNALAVVKKE 138

Query: 1595 KHSVKHXXXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINI 1416
            +  +K                PLS R+     KG+  + N+G+  +    + S+   +N+
Sbjct: 139  E--IKDGNGLKSDDNDSEDDKPLSARL-----KGNTKNVNQGIGASKADAAISE---VNV 188

Query: 1415 KNEESDDDDEMPLSSRFXXXXXXXXXXXXXXSDEKKPMASKLQQNGSTMRDDQRKSTPVF 1236
            K +  D DDE+PLSSRF              SDEKKP+ASK+QQNGST R+ Q+KS+ V 
Sbjct: 189  KTDPEDSDDEVPLSSRFPKSNAGTSGAKPIDSDEKKPLASKVQQNGSTSRETQQKSSSVP 248

Query: 1235 NKRPLDXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDDHVPIAQRIKKSASSD 1056
             KRPL              K+S  S+ +K  QV++K E KA+DDDH+PI+QR+K SA S 
Sbjct: 249  VKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKKADDDDHIPISQRMKNSAPSV 308

Query: 1055 GKSLSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQK-WTTLVHNGVI 879
             KS++   KA                            KM P SG+GQK WTTLVHNGVI
Sbjct: 309  KKSVTNTAKATKSVSSSSKKINKKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTLVHNGVI 368

Query: 878  FPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGK 699
            FPPPY PHGVKMLYKGK V+LTPEQEEVATMFAVM+DTDY +K KF ENF  DW+K+LGK
Sbjct: 369  FPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLLGK 428

Query: 698  NHIIQKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKV 519
            NH+IQ  E CDF+PIY+WHQ                            MWA++DGVKEKV
Sbjct: 429  NHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEKLKQEEKYMWAIVDGVKEKV 488

Query: 518  GNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNT 339
            GNFRVEPPGLFRGRGEHPKMGKLK+RI+PSDITINIGK  PIPECPIPGE W+EV+HDNT
Sbjct: 489  GNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVPIPECPIPGESWKEVKHDNT 548

Query: 338  VTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNK 159
            VTWLAFWNDPINPKEFKYVFLAASSSLKGQSD+EKYEK+R LK+YI  IR AYT+DF ++
Sbjct: 549  VTWLAFWNDPINPKEFKYVFLAASSSLKGQSDREKYEKARKLKDYIHSIRAAYTKDFVSR 608

Query: 158  DVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            D T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV  +PPNKL+
Sbjct: 609  DGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVGNVECIPPNKLK 660


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score =  610 bits (1573), Expect = e-172
 Identities = 337/588 (57%), Positives = 386/588 (65%), Gaps = 6/588 (1%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSKGLPSSANQLNHSSKQNSS-IVKEEKHS-VKHX 1575
            VKS  +SP+VS+ SA  SPV S  ANSK   S + ++   ++  S+ ++KEEK S ++  
Sbjct: 97   VKSPLSSPKVSTSSAKKSPVSSLPANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLA 156

Query: 1574 XXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDD 1395
                          PLS+R SA  SKG+ N  +K          +  KP      E  D 
Sbjct: 157  SAIINDSEDSDDGKPLSLRHSASSSKGNTNQVSK----------EGSKP------ENEDS 200

Query: 1394 DDEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDDQ-RKSTPVFNKRPL 1221
            DDE PLSSRF                D+ KP+A KLQ NGS MRD Q  K + + NKRP 
Sbjct: 201  DDEKPLSSRFPLKSGVGESTSKAYDSDDDKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPP 260

Query: 1220 DXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDD--HVPIAQRIKKSASSDGKS 1047
                          KLS  + P    Q S+K EPKAEDDD  H+PI+QRIKKS +S+ KS
Sbjct: 261  GDIKSSNQLSVKKPKLSSVTAPTNKKQASVKPEPKAEDDDDDHLPISQRIKKSPTSESKS 320

Query: 1046 LSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQKWTTLVHNGVIFPPP 867
             S+ +K                             K+ PSSGEG+KW  L HNGVIFPPP
Sbjct: 321  -SSIKKTTKVVSSSVKKVNKKSKKVMKNSKYSKSSKVPPSSGEGKKWNKLEHNGVIFPPP 379

Query: 866  YKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHII 687
            YKPHG+KMLYKGKPVDLTPEQEEVATMFAVM+DTDY  K +F ENF  DWKKILGKNH+I
Sbjct: 380  YKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVI 439

Query: 686  QKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFR 507
            Q  E+CDF PIYEWHQ+                           MWA +DG KEKVGNFR
Sbjct: 440  QNLENCDFSPIYEWHQSEKEKKKQMTTEEKKALKEEKLKQEEKYMWAWVDGKKEKVGNFR 499

Query: 506  VEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWL 327
            VEPPGLFRGRGEHPKMGKLK+RIRP DITINIGK APIPECP+PGERW+EVRHDNTVTWL
Sbjct: 500  VEPPGLFRGRGEHPKMGKLKKRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWL 559

Query: 326  AFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTK 147
            AFWNDPINPKEFKYVFLAASS+LKG SDKEKYEK+R LK+YI+GIR AYT+DF +KD TK
Sbjct: 560  AFWNDPINPKEFKYVFLAASSTLKGLSDKEKYEKARLLKDYIQGIRAAYTKDFASKDPTK 619

Query: 146  RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            +QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+
Sbjct: 620  KQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK 667


>ref|XP_002317355.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222860420|gb|EEE97967.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 860

 Score =  601 bits (1550), Expect = e-169
 Identities = 330/571 (57%), Positives = 379/571 (66%), Gaps = 2/571 (0%)
 Frame = -1

Query: 1709 SANASPVKSSLANSKGLPSSANQLNHSSKQNSSIVKEEKHSVKHXXXXXXXXXXXXXXXP 1530
            S+NASPVKS + + K   SSA           S V     +VK                P
Sbjct: 69   SSNASPVKSPIGSPKASASSAKASPMKPPVTYSRVPSSSIAVKEETKPIVDDDDSEDDKP 128

Query: 1529 LSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDDDEMPLSSRFXXXXX 1350
            LS R      KGS N+ANKG++     P++       +K+E SDDD E+PLSSRF     
Sbjct: 129  LSSRF-----KGSTNNANKGVTV----PAR-------VKDEHSDDD-EVPLSSRFAAKSN 171

Query: 1349 XXXXXXXXXSD-EKKPMASKLQQNGSTMRDDQRKSTPVFNKRPLDXXXXXXXXXXXXXKL 1173
                     S  EK  + SK+Q NGST +D Q+KS+ V  KRP+D             KL
Sbjct: 172  AGSSSCKTISSSEKILLVSKIQLNGSTAKDKQQKSSAVPTKRPMDNKVPSNQSFAKKPKL 231

Query: 1172 SGASQPIKNNQVSIKAEPKAEDDDHVPIAQRIKKSASSDGKSLSANQKAPXXXXXXXXXX 993
            S AS      QV++KAE KA+DDDH+ I+QR+KK++SS  KSLS  Q             
Sbjct: 232  SDAST---TKQVTVKAELKADDDDHLTISQRMKKASSSSNKSLSVKQNVTKVVSFSSKKT 288

Query: 992  XXXXXXXXXXXXXXXXXKMQPSSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYKGKPVDL 816
                             K+QP S +GQK W TLVHNGVIFPPPYKPHGVKMLYKGKPVDL
Sbjct: 289  TKNNKKQMQNSKYSKSTKVQPGSSDGQKKWKTLVHNGVIFPPPYKPHGVKMLYKGKPVDL 348

Query: 815  TPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQKFEDCDFRPIYEWHQA 636
            TPEQEEVATMFAVM DT+Y +K +F++NF  DW+ +LGKNH+IQK E CDF PIYEWHQ 
Sbjct: 349  TPEQEEVATMFAVMKDTEYVQKPQFLQNFWNDWRTLLGKNHVIQKLEACDFNPIYEWHQK 408

Query: 635  XXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRVEPPGLFRGRGEHPKMG 456
                                       MWA+++GVKEKVGNFRVEPPGLFRGRGEHPKMG
Sbjct: 409  EKEKKKQMSTEEKKAVREEKLKQEEMYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMG 468

Query: 455  KLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLAFWNDPINPKEFKYVFL 276
            KLK RIRPSDITINIGK APIP+CPIPGERW+EV+HDNTVTWLAFWNDPINPKEFKYVFL
Sbjct: 469  KLKSRIRPSDITINIGKDAPIPKCPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFL 528

Query: 275  AASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKRQIAVATYLIDKLALRA 96
            AASSSLKGQSDKEKYEK+R LK+YI  IRTAYT+DF +KD+TKRQIAVATYLIDKLALRA
Sbjct: 529  AASSSLKGQSDKEKYEKARKLKDYIHNIRTAYTKDFASKDITKRQIAVATYLIDKLALRA 588

Query: 95   GNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            GNEKDDDEADTVGCCTLKV NV  +PPNKL+
Sbjct: 589  GNEKDDDEADTVGCCTLKVANVECIPPNKLK 619


>ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis vinifera]
          Length = 883

 Score =  595 bits (1535), Expect = e-167
 Identities = 332/591 (56%), Positives = 375/591 (63%), Gaps = 9/591 (1%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSKGLPSSANQLNHSSKQNSSIVKEEKHSVKHXXX 1569
            VK S    E     ++  P+K+ + +S G    +  LN  S   SS   E K  VK    
Sbjct: 58   VKKSDGDSEDEVPLSSKFPLKTYVRSSSGKSLGSKGLNSPSL--SSHPPETKVGVKESSD 115

Query: 1568 XXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDDD 1389
                         L  R  A  SK  ++   KGLS+      QSQK  +N KN   D +D
Sbjct: 116  DSEDEIPLLLKLQLKSRKGASSSKLLDS---KGLSSPASSRPQSQKAKVNNKNLSDDSED 172

Query: 1388 EMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDDQRKSTPVF-NKRPLDX 1215
            E+PLSS+F              + DEKKP+ S L+ NG + +DD+R  +P   NKRPL  
Sbjct: 173  EIPLSSKFRLKTGMGASLDKLDNFDEKKPLTSTLKPNGISKKDDERVKSPKGQNKRPLGQ 232

Query: 1214 XXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDD-------HVPIAQRIKKSASSD 1056
                        KL   S   K  QVS+KAE K +DDD       + P  +R+KKS SSD
Sbjct: 233  ANTSHHSSSKKPKLLDGSVKGKVKQVSVKAEQKDDDDDDNDDDDEYTPTVKRLKKSVSSD 292

Query: 1055 GKSLSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQKWTTLVHNGVIF 876
             K  S  +  P                            + P+SGEGQKWTTL HNGVIF
Sbjct: 293  NKKASKTKVIPSSRKKATKKAKKSKKLAKSSKYSKSTK-VPPNSGEGQKWTTLEHNGVIF 351

Query: 875  PPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKN 696
            PPPYKPHGVKMLY G+PVDLTPEQEEVATMFAVM DTDYA K +FIENFM DW+  LGKN
Sbjct: 352  PPPYKPHGVKMLYNGRPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRVRLGKN 411

Query: 695  HIIQKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVG 516
            H+I+KFE CDF PIYEWH+                            MWAV+DGVKEKVG
Sbjct: 412  HVIKKFELCDFTPIYEWHEKEKEKKKQMTTEEKKALKEEKLKQEDKYMWAVVDGVKEKVG 471

Query: 515  NFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTV 336
            NFRVEPPGLFRGRGEHPKMGKLK+RI PSDITINIGK AP+PECPIPGERW+EVRHDNTV
Sbjct: 472  NFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGKEAPVPECPIPGERWKEVRHDNTV 531

Query: 335  TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKD 156
            TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEK+R LK+YI+ IR  YT+DFTNKD
Sbjct: 532  TWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIQNIRATYTKDFTNKD 591

Query: 155  VTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
              KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV LVPPNKLE
Sbjct: 592  TMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNKLE 642


>ref|XP_002529020.1| DNA topoisomerase type I, putative [Ricinus communis]
            gi|223531500|gb|EEF33331.1| DNA topoisomerase type I,
            putative [Ricinus communis]
          Length = 891

 Score =  595 bits (1535), Expect = e-167
 Identities = 327/588 (55%), Positives = 384/588 (65%), Gaps = 11/588 (1%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSKGLPSSANQLNHSSKQNSS-IVKEEKH------ 1590
            VKS   SP+ S+ SA ASP++S +ANSKG  S   QL  +SKQN+S +VK+         
Sbjct: 76   VKSPIGSPKASTSSAKASPLRSPVANSKGSSSLDEQLKQASKQNASNVVKDVSSAKPEIG 135

Query: 1589 --SVKHXXXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINI 1416
              SVKH               PLS R      KG+ N+ +K ++               +
Sbjct: 136  LKSVKHETKSNGDDEDSEDDLPLSAR-----RKGNTNNVSKVVTAPK-----------RV 179

Query: 1415 KNEESDDDDEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDDQRKSTPV 1239
            K+E+SDDD ++PL SRF              +  EKKP+ SK+QQNGST +D Q+K+  +
Sbjct: 180  KDEDSDDD-KVPLCSRFPMKSTAGTSGNKPNNISEKKPLPSKVQQNGSTSKDKQQKAPLI 238

Query: 1238 FNKRPLDXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDDHVPIAQRIKKSASS 1059
              KRPLD             KLS  S   K  Q ++KAE   +D D +PIAQR K   SS
Sbjct: 239  PTKRPLDKANSSEQSSIKKPKLSAGSTITKVKQATVKAEE--DDPDDIPIAQRKKSLGSS 296

Query: 1058 DGKSLSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQK-WTTLVHNGV 882
            + K  SA QKA                            K+QPSS +GQK WTTL+HNGV
Sbjct: 297  ESKLSSAKQKAIKVVSSSFKKPIKKNKKQMKNTKYSKSTKVQPSSTDGQKKWTTLIHNGV 356

Query: 881  IFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILG 702
            IFPPPYKPHG+K+LYKG+PVDL PEQEEVATMFAVM DTDY +K KF+ENF  DW+K+LG
Sbjct: 357  IFPPPYKPHGIKILYKGRPVDLAPEQEEVATMFAVMKDTDYMQKPKFLENFWNDWRKLLG 416

Query: 701  KNHIIQKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEK 522
            +NH+IQK EDCDF PIYEWH+                            MWA++DGVKEK
Sbjct: 417  RNHVIQKLEDCDFTPIYEWHEREKEKKKQMSTEEKKAQKEEKLRQEEKYMWAIVDGVKEK 476

Query: 521  VGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDN 342
            VGNFRVEPP LFRGRGEHPKMGKLK+RI+PSDITINIGK APIPECPIPGE W+EV+HDN
Sbjct: 477  VGNFRVEPPALFRGRGEHPKMGKLKKRIQPSDITINIGKDAPIPECPIPGESWKEVKHDN 536

Query: 341  TVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTN 162
            TVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEK+R LK+YI  IR AY +D  +
Sbjct: 537  TVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIRAAYQKDLRS 596

Query: 161  KDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVP 18
            KD+TK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV  +P
Sbjct: 597  KDITKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIP 644


>ref|XP_007020667.1| DNA topoisomerase I alpha isoform 4, partial [Theobroma cacao]
            gi|508720295|gb|EOY12192.1| DNA topoisomerase I alpha
            isoform 4, partial [Theobroma cacao]
          Length = 733

 Score =  595 bits (1534), Expect = e-167
 Identities = 310/510 (60%), Positives = 351/510 (68%), Gaps = 2/510 (0%)
 Frame = -1

Query: 1526 SVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDDDEMPLSSRFXXXXXX 1347
            S+ +SA L KG +N  NKG ST+ P  S+   P   +K    D DDE PLS+RF      
Sbjct: 28   SLPLSARL-KGISNQGNKGASTSAPAQSRRLVPKTEVKVSAEDPDDEAPLSARFNVKSNT 86

Query: 1346 XXXXXXXXS-DEKKPMASKLQQNGSTMRDDQRKSTPVFNKRPLDXXXXXXXXXXXXXKLS 1170
                      DEKKP+ASK+QQNGS M+  Q+ S+ +  KRPLD             K S
Sbjct: 87   GTSSSRLHDCDEKKPLASKIQQNGSIMKGKQQNSSTLSGKRPLDKGNSSDHSSAKKPKTS 146

Query: 1169 GASQPIKNNQVSIKAEPKAEDDDHVPIAQRIKKSASSDGKSLSANQKAPXXXXXXXXXXX 990
             A   +K  QV++KAE   EDDDH+PIAQR+KKS +S+ K  S  QK             
Sbjct: 147  DAPTTMKTKQVTVKAEKADEDDDHMPIAQRMKKSTASNSKLSSMKQKTTKVVSSSFKKIN 206

Query: 989  XXXXXXXXXXXXXXXXKMQPSSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLT 813
                            K+ PSSG+GQK W+TLVHNGVIFP PY PHGVKMLY G+PVDLT
Sbjct: 207  KKSKKEMKSSKYIKSTKVPPSSGDGQKKWSTLVHNGVIFPSPYTPHGVKMLYDGRPVDLT 266

Query: 812  PEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQKFEDCDFRPIYEWHQAX 633
            PEQEEVATMFAVM DTDY  K +F +NF  DW K+LGKNH I+  + CDF PIYEWH   
Sbjct: 267  PEQEEVATMFAVMKDTDYMSKTQFKKNFWEDWSKLLGKNHTIKDLDRCDFTPIYEWHLQE 326

Query: 632  XXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRVEPPGLFRGRGEHPKMGK 453
                                      MWA++DGVKEKVGNFRVEPPGLFRGRGEHPKMGK
Sbjct: 327  KEKKKQMSSEEKKALKEEKLKQEEKFMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGK 386

Query: 452  LKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLAFWNDPINPKEFKYVFLA 273
            LKRRIRPSDITINIGK APIPECPIPGERW++++HDNTVTWLAFWNDPINPKEFKYVFLA
Sbjct: 387  LKRRIRPSDITINIGKDAPIPECPIPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLA 446

Query: 272  ASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKRQIAVATYLIDKLALRAG 93
            ASSSLKGQSDKEKYEK+R LK+YI+ IR AYT+DFT KDV KRQIAVATYLIDKLALRAG
Sbjct: 447  ASSSLKGQSDKEKYEKARMLKDYIKNIRAAYTKDFTTKDVMKRQIAVATYLIDKLALRAG 506

Query: 92   NEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            NEKDDDEADTVGCCTLKV NV  +PPNKL+
Sbjct: 507  NEKDDDEADTVGCCTLKVGNVECIPPNKLK 536


>ref|XP_002266885.1| PREDICTED: DNA topoisomerase 1 [Vitis vinifera]
            gi|296082698|emb|CBI21703.3| unnamed protein product
            [Vitis vinifera]
          Length = 857

 Score =  592 bits (1527), Expect = e-166
 Identities = 321/518 (61%), Positives = 356/518 (68%), Gaps = 9/518 (1%)
 Frame = -1

Query: 1529 LSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDDDEMPLSSRFXXXXX 1350
            LSVR+S+GL KG  +  N GL        +        K E+ DDDD++PLSS+F     
Sbjct: 121  LSVRLSSGLPKGKGSSNNVGLGRGGVGGVK--------KEEDDDDDDKIPLSSKFQLKS- 171

Query: 1349 XXXXXXXXXSDEKKPMASKLQQNGSTMRDDQRKSTPVFNK-RPLDXXXXXXXXXXXXXK- 1176
                      DEKKP+  K+ QNG T  D + KS  V NK RPLD             K 
Sbjct: 172  ----------DEKKPLPLKVNQNGGT--DKRDKSPTVLNKKRPLDGVNSSLGQSSLVKKP 219

Query: 1175 -LSGAS-QPIKNNQVSIKAEPKAEDDDH--VPIAQRIKKS-ASSDGKSLSANQKAP--XX 1017
             +SG S QP K    + KAEPK EDDD   +PI+QR+KKS ASS  K + A QK      
Sbjct: 220  KISGQSAQPFKVTHATAKAEPKVEDDDDDDMPISQRMKKSGASSGNKPVPAKQKVTKVVS 279

Query: 1016 XXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLY 837
                                     K+ PSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLY
Sbjct: 280  STSFKKTKDIKSKKMEKNSKYSKSTKVPPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLY 339

Query: 836  KGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQKFEDCDFRP 657
            KGKPVDLTPEQEEVATMFAVM+DTDY +KEKF ENFM DW+KILGKNH+IQ+ +DCDF P
Sbjct: 340  KGKPVDLTPEQEEVATMFAVMLDTDYMQKEKFKENFMADWRKILGKNHVIQRLDDCDFTP 399

Query: 656  IYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRVEPPGLFRGR 477
            IYEWHQ                            MWA++DGVKEKVGNFRVEPPGLFRGR
Sbjct: 400  IYEWHQEEKEKKKQMSTEEKKTLKEEKLKLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGR 459

Query: 476  GEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLAFWNDPINPK 297
            GEHPKMGKLKRRI PSDITINIGK + IPECPIPGE W+EV+HDNTVTWLAFWNDPINPK
Sbjct: 460  GEHPKMGKLKRRIHPSDITINIGKNSQIPECPIPGESWKEVKHDNTVTWLAFWNDPINPK 519

Query: 296  EFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKRQIAVATYLI 117
            EFKYVFLAASSSLKGQSDKEKYEK+R LKNYI+ IR  YT+DF +KD+TKRQIAVATYLI
Sbjct: 520  EFKYVFLAASSSLKGQSDKEKYEKARKLKNYIKDIRATYTKDFVSKDITKRQIAVATYLI 579

Query: 116  DKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            DKLALRAGNEKDDDEADTVGCCTLKVENV   PPN L+
Sbjct: 580  DKLALRAGNEKDDDEADTVGCCTLKVENVIPEPPNSLQ 617


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score =  592 bits (1525), Expect = e-166
 Identities = 339/613 (55%), Positives = 382/613 (62%), Gaps = 31/613 (5%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSK---GLPSSANQLNHSSKQNSSIVKEEKHSVKH 1578
            VKS  +SP+ S+ SA ASP+ S+ ANSK      S+A Q NH   ++S+   E K SV  
Sbjct: 83   VKSPLSSPKASNSSAKASPITSAGANSKPSASATSTAKQQNHH--KSSAAFIEPKPSVP- 139

Query: 1577 XXXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESD 1398
                           PLS R     SKG +NHANK            ++P I    E  D
Sbjct: 140  AAKANSNSESSDDEKPLSARTFGCSSKGKSNHANK----EGGDSCSIRRPVIE---ESED 192

Query: 1397 DDDEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDD-QRKSTPVFNKRP 1224
             +DE PLS RF                DEKKP+A+K+Q NGS  RD    KS  + NKRP
Sbjct: 193  SEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSPMNKSASLSNKRP 252

Query: 1223 LDXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDD------------------- 1101
                           KLS     I N Q ++K EPKAEDDD                   
Sbjct: 253  PGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTATSKP 312

Query: 1100 ------HVPIAQRIKKSASSDGKSLSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXK 939
                  +VPI+QRIKKS +S  KS +  +KA                            K
Sbjct: 313  KDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTAYTKSSK 372

Query: 938  MQPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDY 759
            + P SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEVATMFAVM+DTDY
Sbjct: 373  VPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDY 432

Query: 758  AKKEKFIENFMTDWKKILGKNHIIQKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXX 579
              K +F ENF +DWKK+LGKNH IQ  EDCDF PIYEWHQ                    
Sbjct: 433  MNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEE 492

Query: 578  XXXXXXXXMWAVLDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGA 399
                    MWA++DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP DITINIGK A
Sbjct: 493  KLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDA 552

Query: 398  PIPECPIPGERWREVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSR 219
            PIPECPIPGERW+EVR+DNTVTWLA+WNDPIN KEFKYVFLAASS+LKGQSDKEKYEK+R
Sbjct: 553  PIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKEKYEKAR 612

Query: 218  TLKNYIEGIRTAYTRDFT-NKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK 42
             LK+YI GIR AYT+DFT NKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK
Sbjct: 613  LLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK 672

Query: 41   VENVTLVPPNKLE 3
            VENV  VPPN L+
Sbjct: 673  VENVEPVPPNILK 685


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score =  591 bits (1523), Expect = e-166
 Identities = 339/613 (55%), Positives = 381/613 (62%), Gaps = 31/613 (5%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSK---GLPSSANQLNHSSKQNSSIVKEEKHSVKH 1578
            VKS  +SP+ S+ SA ASP+ S  ANSK      S+A Q NH   ++S+   E K SV  
Sbjct: 83   VKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAKQQNHH--KSSAAFIEPKPSVP- 139

Query: 1577 XXXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESD 1398
                           PLS R     SKG +NHANK            ++P I    E  D
Sbjct: 140  AAKANSNSESSDDEKPLSARTFGCSSKGKSNHANK----EGGDSCSIRRPVIE---ESED 192

Query: 1397 DDDEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDD-QRKSTPVFNKRP 1224
             +DE PLS RF                DEKKP+A+K+Q NGS  RD    KS  + NKRP
Sbjct: 193  SEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQPNGSASRDSPMNKSASLSNKRP 252

Query: 1223 LDXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDD------------------- 1101
                           KLS     I N Q ++K EPKAEDDD                   
Sbjct: 253  PGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTATSKP 312

Query: 1100 ------HVPIAQRIKKSASSDGKSLSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXK 939
                  +VPI+QRIKKS +S  KS +  +KA                            K
Sbjct: 313  KDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTAYTKSSK 372

Query: 938  MQPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDY 759
            + P SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEVATMFAVM+DTDY
Sbjct: 373  VPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDY 432

Query: 758  AKKEKFIENFMTDWKKILGKNHIIQKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXX 579
              K +F ENF +DWKK+LGKNH IQ  EDCDF PIYEWHQ                    
Sbjct: 433  MNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEE 492

Query: 578  XXXXXXXXMWAVLDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGA 399
                    MWA++DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP DITINIGK A
Sbjct: 493  KLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDA 552

Query: 398  PIPECPIPGERWREVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSR 219
            PIPECPIPGERW+EVR+DNTVTWLA+WNDPIN KEFKYVFLAASS+LKGQSDKEKYEK+R
Sbjct: 553  PIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKEKYEKAR 612

Query: 218  TLKNYIEGIRTAYTRDFT-NKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK 42
             LK+YI GIR AYT+DFT NKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK
Sbjct: 613  LLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK 672

Query: 41   VENVTLVPPNKLE 3
            VENV  VPPN L+
Sbjct: 673  VENVEPVPPNILK 685


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score =  589 bits (1518), Expect = e-165
 Identities = 340/613 (55%), Positives = 380/613 (61%), Gaps = 31/613 (5%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSK---GLPSSANQLNHSSKQNSSIVKEEKHSVKH 1578
            VKS  +SP+ S+ SA ASP+ S  ANSK      S+A Q NH   ++S+   E K SV  
Sbjct: 82   VKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAKQQNHH--KSSAAFIEPKPSVP- 138

Query: 1577 XXXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESD 1398
                           PLS R     SKG +NHANK            ++P I    E  D
Sbjct: 139  AAKANSNSESSDDEKPLSARTFGCSSKGKSNHANK----EGGDSCSIRRPVIE---ESED 191

Query: 1397 DDDEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDD-QRKSTPVFNKRP 1224
             +DE PLS RF                DEKKP+A+K+QQNGS  RD    KS  + NKRP
Sbjct: 192  SEDEKPLSCRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSASRDGPMNKSASLSNKRP 251

Query: 1223 LDXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDD------------------- 1101
                           KLS     I N Q ++K EPKAEDDD                   
Sbjct: 252  PGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQSATSKP 311

Query: 1100 ------HVPIAQRIKKSASSDGKSLSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXK 939
                  +VPI+QRIKKS +S  KS    +KA                            K
Sbjct: 312  KDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNKNSKKVIKKTAYTKSSK 371

Query: 938  MQPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDY 759
            + P SGEGQKWTTLVHNGVIFPPPYKPHGVKMLYK +P+ LTPEQEEVATMFAVM+DTDY
Sbjct: 372  VPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEVATMFAVMLDTDY 431

Query: 758  AKKEKFIENFMTDWKKILGKNHIIQKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXX 579
              K  F ENF +DWKKILGKNH+IQ  EDCDF PIYEWHQ                    
Sbjct: 432  MNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALKEE 491

Query: 578  XXXXXXXXMWAVLDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGA 399
                    MWA++DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP DITINIGK A
Sbjct: 492  KLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDA 551

Query: 398  PIPECPIPGERWREVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSR 219
            PIPECPIPGERW+EVR+ NTVTWLA+WNDPIN KEFKYVFLAASS+LKGQSDKEKYEK+R
Sbjct: 552  PIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTLKGQSDKEKYEKAR 611

Query: 218  TLKNYIEGIRTAYTRDFT-NKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK 42
             LK+YI GIR AYT+DFT NKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK
Sbjct: 612  LLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK 671

Query: 41   VENVTLVPPNKLE 3
            VENV  VPPN L+
Sbjct: 672  VENVEPVPPNILK 684


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score =  587 bits (1512), Expect = e-165
 Identities = 338/615 (54%), Positives = 377/615 (61%), Gaps = 33/615 (5%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSK---GLPSSANQLNHSSKQNSSIVKEEKHSVKH 1578
            VKS  +SP+ S+ SA ASP+ S  ANSK      S+A Q NH   ++S+   E K SV  
Sbjct: 82   VKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAKQQNHH--KSSAAFIEPKPSVP- 138

Query: 1577 XXXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESD 1398
                           PLS R     SKG +NHANK           S      +  E  D
Sbjct: 139  AAKANSNSESSDDEKPLSARTFGCSSKGKSNHANK-------EGGDSCSIRRRVIEESED 191

Query: 1397 DDDEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDD-QRKSTPVFNKRP 1224
             +DE PLS RF                DEKKP+A+K+QQNGS  RD    KS  + NKRP
Sbjct: 192  SEDEKPLSRRFTSKSSLGESTSKSYDSDEKKPLAAKVQQNGSVSRDGPMNKSASLSNKRP 251

Query: 1223 LDXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEP------------------------- 1119
                           KLS     I N Q ++K EP                         
Sbjct: 252  PGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIPLSQRGKKSQAATS 311

Query: 1118 --KAEDDDHVPIAQRIKKSASSDGKSLSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXX 945
              K EDDD+VPIAQRIKKS +S  KS +  +KA                           
Sbjct: 312  KPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKNSKKVIKKTAYTKS 371

Query: 944  XKMQPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDT 765
             K+ P SGEGQKWTTLVHNGVIFPPPY PHGVKMLYK +P+ LTPEQEEVATMFAVM+DT
Sbjct: 372  SKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQEEVATMFAVMLDT 431

Query: 764  DYAKKEKFIENFMTDWKKILGKNHIIQKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXX 585
            DY  K +F ENF +DWKK+LGKNH IQ  EDCDF PIYEWHQ                  
Sbjct: 432  DYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQMTTEEKKALK 491

Query: 584  XXXXXXXXXXMWAVLDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGK 405
                      MWA++DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP DITINIGK
Sbjct: 492  EDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGK 551

Query: 404  GAPIPECPIPGERWREVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEK 225
             APIPECPIPGERW+EVR+DNTVTWLAFW DPIN KEFKYVFLAASS+LKGQSDKEKYEK
Sbjct: 552  DAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASSTLKGQSDKEKYEK 611

Query: 224  SRTLKNYIEGIRTAYTRDFT-NKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCT 48
            +R LK+YI GIR AYT+DFT NKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCT
Sbjct: 612  ARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCT 671

Query: 47   LKVENVTLVPPNKLE 3
            LKVENV  VPPN L+
Sbjct: 672  LKVENVEPVPPNILK 686


>gb|AAD08711.1| topoisomerase I [Nicotiana tabacum] gi|14626487|gb|AAK69776.1|
            topoisomerase I [Nicotiana tabacum]
          Length = 852

 Score =  585 bits (1508), Expect = e-164
 Identities = 325/581 (55%), Positives = 379/581 (65%), Gaps = 1/581 (0%)
 Frame = -1

Query: 1742 SSTASPEVSSLSANASPVKSSLANSKGLPSSANQLNHSSKQNSSIVKEEKHSVKHXXXXX 1563
            S   SP+ S  S   SP      NS+   S+ NQ    ++Q+  +  E K +V+      
Sbjct: 82   SPFTSPKASPSSGRTSPAP----NSRPSASAGNQAKDVNQQSKIVPNEPKQAVEPKSEPN 137

Query: 1562 XXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDDDEM 1383
                      PLS R+S+GLSK +++HANK L T+     +S+ P      ++ D DDE+
Sbjct: 138  DEAEDSEDDKPLSARLSSGLSKSNSSHANKVLGTS-ASVQKSRPP------KKEDSDDEI 190

Query: 1382 PLSSRFXXXXXXXXXXXXXXSDEKKPMASKLQQNGSTMRDDQRKSTPVFNKRPLDXXXXX 1203
            PL+SRF              + E+  +  K++QNG         ST V +KRP       
Sbjct: 191  PLASRFQLKSNAGASTSKSSNSEE--VKPKIRQNGLP-------STTVLSKRPPGDVSLL 241

Query: 1202 XXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDDH-VPIAQRIKKSASSDGKSLSANQKA 1026
                             + ++ S+K E K EDDD  VPI+QRIKKS +S  K LS+ +KA
Sbjct: 242  LRLQLKSLGFLMHLHLFRVSEASVKPEKKTEDDDDDVPISQRIKKSVASASK-LSSAKKA 300

Query: 1025 PXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQKWTTLVHNGVIFPPPYKPHGVK 846
                                         +QPSSGEGQKWTTLVHNGVIFPPPYKPHGVK
Sbjct: 301  TKVVSSSMKTKKKLKKSKYSKSSK-----LQPSSGEGQKWTTLVHNGVIFPPPYKPHGVK 355

Query: 845  MLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQKFEDCD 666
            MLYKGKPVDLTPEQEEVATM+AVM+DTDY  K +F ENFM DW+KILGKNH+IQ  +DCD
Sbjct: 356  MLYKGKPVDLTPEQEEVATMYAVMLDTDYMSKLQFKENFMNDWRKILGKNHVIQNLDDCD 415

Query: 665  FRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRVEPPGLF 486
            F PIYE   +                           MWA++DGVKEKVGNFRVEPPGLF
Sbjct: 416  FTPIYERPSSEKEKKKQMSTKRKRPLREEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLF 475

Query: 485  RGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLAFWNDPI 306
            RGRGEHPKMGKLKRRIRP+DITINIGKGAPIPECPIPGERW+EVRHDNTVTWLAFWNDPI
Sbjct: 476  RGRGEHPKMGKLKRRIRPNDITINIGKGAPIPECPIPGERWKEVRHDNTVTWLAFWNDPI 535

Query: 305  NPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKRQIAVAT 126
            NP+EFKYVFLAASSSLKGQSDKEKYEK+R LK+YIEGIR+AYT+DFT+KD  KRQIAVAT
Sbjct: 536  NPREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIEGIRSAYTKDFTSKDPVKRQIAVAT 595

Query: 125  YLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            YLIDKLALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+
Sbjct: 596  YLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK 636


>gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Mimulus guttatus]
          Length = 883

 Score =  581 bits (1498), Expect = e-163
 Identities = 328/585 (56%), Positives = 373/585 (63%), Gaps = 3/585 (0%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSKGLPSSANQLNHSSKQNSSIVKEEKHSVKHXXX 1569
            V+ S  SP+ S+ S  ASP+KS   NSK   S   +    SK   S +KEE         
Sbjct: 85   VRPSLVSPKSSNSSVKASPIKSPDVNSKPSTSVVGE----SKSVKSTIKEENSEDSEDDK 140

Query: 1568 XXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESDDDD 1389
                         LS R  AG SK + N  NK  + N    S   KP         D DD
Sbjct: 141  P------------LSARQVAGSSKNNPNQTNKPNAPNLGKKSNVPKPE--------DSDD 180

Query: 1388 EMPLSSRFXXXXXXXXXXXXXXS-DEKKPM-ASKLQQNGSTMRDDQRKSTPVFNKRPLDX 1215
            E+PLS++F                +EKKP+ A K  +NGS     +RK + V  KRP D 
Sbjct: 181  EIPLSAKFQGKSNAGASTSRSSHSEEKKPLVARKPDKNGSA--STERKPSTVLQKRPADG 238

Query: 1214 XXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDD-DHVPIAQRIKKSASSDGKSLSA 1038
                        KLS  S   K+ + S+K E KAEDD D VP++QR KKS + + K   A
Sbjct: 239  VASAGQSNLKKPKLSD-SLASKDKKASVKPEVKAEDDEDLVPLSQRTKKSTTPEKKPSPA 297

Query: 1037 NQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXKMQPSSGEGQKWTTLVHNGVIFPPPYKP 858
             +                              K+ PSSG+GQKWTTLVHNGVIFPPPYKP
Sbjct: 298  LKTNNKTNSKTNSKTNKKSKQVSKDNNYSKSSKLPPSSGDGQKWTTLVHNGVIFPPPYKP 357

Query: 857  HGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDYAKKEKFIENFMTDWKKILGKNHIIQKF 678
            HGVKMLYKGKPV+LTPEQEEVATM+AVM++TDY KK +F ENFMTDWKKILGKNH+IQ  
Sbjct: 358  HGVKMLYKGKPVNLTPEQEEVATMYAVMLETDYLKKPQFKENFMTDWKKILGKNHVIQSL 417

Query: 677  EDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXXXXXXXXXXMWAVLDGVKEKVGNFRVEP 498
            E CDF PIYEWHQ                            MWAVLDGV+EKVGNFRVEP
Sbjct: 418  EHCDFTPIYEWHQREKEKKKQMSTDEKKALKEEKLKLEEKYMWAVLDGVREKVGNFRVEP 477

Query: 497  PGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWREVRHDNTVTWLAFW 318
            PGLFRGRGEHPKMGKLKRRIRPSDITINIG+ APIPECPI GERW+E+RHDNTVTWLA+W
Sbjct: 478  PGLFRGRGEHPKMGKLKRRIRPSDITINIGRDAPIPECPIEGERWKEIRHDNTVTWLAYW 537

Query: 317  NDPINPKEFKYVFLAASSSLKGQSDKEKYEKSRTLKNYIEGIRTAYTRDFTNKDVTKRQI 138
            +DPIN KEFKYVFLAASS+LKGQSDKEKYEK+R LK+YI+GIRTAYTRDF +KD  K+QI
Sbjct: 538  SDPINGKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIQGIRTAYTRDFVSKDPAKKQI 597

Query: 137  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVTLVPPNKLE 3
            AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV  VPPN L+
Sbjct: 598  AVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK 642


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score =  581 bits (1497), Expect = e-163
 Identities = 335/613 (54%), Positives = 378/613 (61%), Gaps = 31/613 (5%)
 Frame = -1

Query: 1748 VKSSTASPEVSSLSANASPVKSSLANSK---GLPSSANQLNHSSKQNSSIVKEEKHSVKH 1578
            VKS  +SP+ S+ SA ASP+ S  ANSK      S+A Q NH   ++S+   E K SV  
Sbjct: 83   VKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQNHH--KSSAAFIEPKPSVP- 139

Query: 1577 XXXXXXXXXXXXXXXPLSVRISAGLSKGSNNHANKGLSTNNPHPSQSQKPNINIKNEESD 1398
                           PL  R S   SKG +NHANK            ++P I    E  D
Sbjct: 140  AAKANSNSESSDDEKPLIARTSGCSSKGKSNHANK----EGGDSCSIRRPVIE---ESED 192

Query: 1397 DDDEMPLSSRFXXXXXXXXXXXXXXS-DEKKPMASKLQQNGSTMRDD-QRKSTPVFNKRP 1224
             +DE PLS RF                DEKKP+A+K+QQNGS  RD    KS  + NKR 
Sbjct: 193  SEDEKPLSRRFPSKSSLGESTSKSYDSDEKKPLATKVQQNGSASRDGPMNKSASLLNKRA 252

Query: 1223 LDXXXXXXXXXXXXXKLSGASQPIKNNQVSIKAEPKAEDDD------------------- 1101
                           KLS     I N Q ++K EPKAEDDD                   
Sbjct: 253  PGEVKSLNQSSLKKAKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQRGKKSQTAASKP 312

Query: 1100 ------HVPIAQRIKKSASSDGKSLSANQKAPXXXXXXXXXXXXXXXXXXXXXXXXXXXK 939
                  + PI+QRIKKS +S  KS +  +KA                            K
Sbjct: 313  KDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKKVIKKTAYTKSSK 372

Query: 938  MQPSSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMIDTDY 759
            + P SGEGQKWTTLVHNGV+F PPYKPHGVKMLYK +P+ LTPEQEEVATMFAVM+DTDY
Sbjct: 373  VPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKXQPLTLTPEQEEVATMFAVMLDTDY 432

Query: 758  AKKEKFIENFMTDWKKILGKNHIIQKFEDCDFRPIYEWHQAXXXXXXXXXXXXXXXXXXX 579
              K +F ENF +DWKK+LGKNH +Q  EDCDF PIYEWHQ                    
Sbjct: 433  MTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQMTTEEKKALKEE 492

Query: 578  XXXXXXXXMWAVLDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGA 399
                    MWA++DGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP DITINIGK A
Sbjct: 493  RLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPRDITINIGKDA 552

Query: 398  PIPECPIPGERWREVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKSR 219
            PIPECPIPGERW+EVR+DNTVTWLAFWNDPIN KE KYVFLAASS+LKGQSDKEKYEK+R
Sbjct: 553  PIPECPIPGERWKEVRNDNTVTWLAFWNDPINQKECKYVFLAASSTLKGQSDKEKYEKAR 612

Query: 218  TLKNYIEGIRTAYTRDFT-NKDVTKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK 42
             LK+YI GIR AYT+DFT NKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK
Sbjct: 613  LLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLK 672

Query: 41   VENVTLVPPNKLE 3
            VENV  VPPN L+
Sbjct: 673  VENVEPVPPNILK 685