BLASTX nr result
ID: Ophiopogon23_contig00021933
seq
BLASTX 2.2.26 [Sep-21-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Ophiopogon23_contig00021933
(1124 letters)
Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects
149,584,005 sequences; 54,822,741,787 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|OXU22772.1| hypothetical protein TSAR_016794 [Trichomalopsis ... 311 7e-95
ref|XP_008213064.1| PREDICTED: insulin-degrading enzyme isoform ... 310 2e-93
ref|XP_001603463.2| PREDICTED: insulin-degrading enzyme isoform ... 310 2e-93
ref|XP_011499186.1| PREDICTED: insulin-degrading enzyme [Ceratos... 300 2e-89
ref|XP_006610177.1| PREDICTED: insulin-degrading enzyme-like, pa... 281 5e-89
ref|XP_971897.2| PREDICTED: insulin-degrading enzyme [Tribolium ... 297 2e-88
ref|XP_015116960.1| PREDICTED: insulin-degrading enzyme isoform ... 296 3e-88
ref|XP_015116959.1| PREDICTED: insulin-degrading enzyme isoform ... 296 3e-88
gb|KOC65772.1| Insulin-degrading enzyme, partial [Habropoda labo... 280 7e-88
ref|XP_008554389.1| PREDICTED: insulin-degrading enzyme isoform ... 294 1e-87
ref|XP_008554388.1| PREDICTED: insulin-degrading enzyme isoform ... 294 2e-87
ref|XP_014206136.1| insulin-degrading enzyme isoform X2 [Copidos... 293 4e-87
ref|XP_014206133.1| insulin-degrading enzyme isoform X1 [Copidos... 293 4e-87
gb|KOC65774.1| Insulin-degrading enzyme, partial [Habropoda labo... 278 4e-87
ref|XP_003701355.1| PREDICTED: insulin-degrading enzyme [Megachi... 289 1e-85
ref|XP_024227556.1| insulin-degrading enzyme isoform X4 [Bombus ... 287 5e-85
ref|XP_012172345.2| LOW QUALITY PROTEIN: insulin-degrading enzym... 287 6e-85
ref|XP_024227555.1| insulin-degrading enzyme isoform X3 [Bombus ... 287 6e-85
ref|XP_024227554.1| insulin-degrading enzyme isoform X2 [Bombus ... 287 6e-85
ref|XP_012248321.2| insulin-degrading enzyme isoform X1 [Bombus ... 287 8e-85
>gb|OXU22772.1| hypothetical protein TSAR_016794 [Trichomalopsis sarcophagae]
Length = 861
Score = 311 bits (796), Expect = 7e-95
Identities = 158/352 (44%), Positives = 225/352 (63%), Gaps = 14/352 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KNFE ++P +YY +++EQ W ++E L+A +T +++ F+P L+SK+HIE L H
Sbjct: 503 KNFEAEQPYQHAAYYLAALMSEQVWVKNELLNACSMLTADRVRQFIPLLMSKMHIECLIH 562
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ ++E L+ V +E KLI S + PLLP+ ++ R+++LP G YLYE NK+ K
Sbjct: 563 GNVTKAEALKTVKNVESKLISSVKDLTPLLPKQLVLYRELELPNGCHYLYEVDNKHHKSS 622
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ G++S++ NMLL+LF QII EPCF+ILRTK QLGYIV SG+ + +GVQGL I
Sbjct: 623 CTQIYYQSGMQSTESNMLLELFTQIISEPCFNILRTKEQLGYIVFSGIRRTNGVQGLRII 682
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQSNK FVE +I+ FM+ M+++I NM+ E FN HK+SL L KP L +Q+ I++
Sbjct: 683 VQSNKHPQFVEERIDAFMESMKDYITNMSDEEFNRHKESLATQRLEKPKMLTSQSGIYWN 742
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVI---------- 254
EI QQYNFDRAN+E +YLK I + I++FYK S + KL I V+
Sbjct: 743 EISMQQYNFDRANVEVAYLKTISRSQIIDFYKDVVHSESPQRHKLSIHVVSTAEGGAAAE 802
Query: 253 ----PTSYKENVIGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
PT E E+Q +I D+L+FK + L+PL++P+N + RKG
Sbjct: 803 DVTSPTPSAEETKKTLEQAEQQPARIQDILQFKTSHPLYPLVKPFNNVPRKG 854
>ref|XP_008213064.1| PREDICTED: insulin-degrading enzyme isoform X2 [Nasonia vitripennis]
ref|XP_008213065.1| PREDICTED: insulin-degrading enzyme isoform X2 [Nasonia vitripennis]
Length = 1016
Score = 310 bits (794), Expect = 2e-93
Identities = 159/352 (45%), Positives = 228/352 (64%), Gaps = 14/352 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KNFE ++P +YY +++EQ W ++E L+A +T +++ F+P L+SK+HIE L H
Sbjct: 658 KNFEAEQPYQHAAYYLAALMSEQVWVKNELLNACSMLTADRVRQFIPLLMSKMHIECLIH 717
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ ++E L+ V +E KLI S + PLLP+ ++ R+++LP G YLYE NK+ K
Sbjct: 718 GNITKAEALKTVKNVESKLISSVKDLTPLLPKQLVLYRELELPNGCHYLYEVDNKHHKSS 777
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ G++S++ NMLL+LF QII EPCF+ILRTK QLGYIV SG+ + +GVQGL I
Sbjct: 778 CTQIYYQSGMQSTESNMLLELFTQIISEPCFNILRTKEQLGYIVFSGIRRTNGVQGLRII 837
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQSNK FVE +I+ FM+ M+++I NM+ E FN HK+SL L KP L +Q+ I++
Sbjct: 838 VQSNKHPQFVEERIDAFMESMKDYITNMSDEEFNRHKESLATQRLEKPKMLTSQSGIYWN 897
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT----SYKE 236
EI QQYNFDRAN+E +YLK I + I++FYK S + KL I V+ T + E
Sbjct: 898 EISMQQYNFDRANVEVAYLKTISRSQIIDFYKDVVHSESPQRHKLSIHVVSTAEGGAAAE 957
Query: 235 NVIGKENS----------NEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
+V S E+Q +I D+L+FK + L+PL++P+N + RKG
Sbjct: 958 DVTSSTPSAEETKKTLEQAEQQPARIQDILQFKTSHPLYPLVKPFNNVPRKG 1009
>ref|XP_001603463.2| PREDICTED: insulin-degrading enzyme isoform X1 [Nasonia vitripennis]
Length = 1020
Score = 310 bits (794), Expect = 2e-93
Identities = 159/352 (45%), Positives = 228/352 (64%), Gaps = 14/352 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KNFE ++P +YY +++EQ W ++E L+A +T +++ F+P L+SK+HIE L H
Sbjct: 662 KNFEAEQPYQHAAYYLAALMSEQVWVKNELLNACSMLTADRVRQFIPLLMSKMHIECLIH 721
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ ++E L+ V +E KLI S + PLLP+ ++ R+++LP G YLYE NK+ K
Sbjct: 722 GNITKAEALKTVKNVESKLISSVKDLTPLLPKQLVLYRELELPNGCHYLYEVDNKHHKSS 781
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ G++S++ NMLL+LF QII EPCF+ILRTK QLGYIV SG+ + +GVQGL I
Sbjct: 782 CTQIYYQSGMQSTESNMLLELFTQIISEPCFNILRTKEQLGYIVFSGIRRTNGVQGLRII 841
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQSNK FVE +I+ FM+ M+++I NM+ E FN HK+SL L KP L +Q+ I++
Sbjct: 842 VQSNKHPQFVEERIDAFMESMKDYITNMSDEEFNRHKESLATQRLEKPKMLTSQSGIYWN 901
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT----SYKE 236
EI QQYNFDRAN+E +YLK I + I++FYK S + KL I V+ T + E
Sbjct: 902 EISMQQYNFDRANVEVAYLKTISRSQIIDFYKDVVHSESPQRHKLSIHVVSTAEGGAAAE 961
Query: 235 NVIGKENS----------NEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
+V S E+Q +I D+L+FK + L+PL++P+N + RKG
Sbjct: 962 DVTSSTPSAEETKKTLEQAEQQPARIQDILQFKTSHPLYPLVKPFNNVPRKG 1013
>ref|XP_011499186.1| PREDICTED: insulin-degrading enzyme [Ceratosolen solmsi marchali]
Length = 1055
Score = 300 bits (768), Expect = 2e-89
Identities = 152/350 (43%), Positives = 228/350 (65%), Gaps = 13/350 (3%)
Frame = -2
Query: 1120 NFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFHG 941
NFET++P +YY V+L+E W ++E L+A +T E+++ F+P LLSK+HIE L HG
Sbjct: 699 NFETEQPYQHAAYYLTVLLSEHIWVKNELLNACSMLTAERVKQFVPLLLSKMHIECLIHG 758
Query: 940 NLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPIA 761
N+ ++E +++V ++E KLI S + PLLP+ ++ R+++LP G +LY+ NK+
Sbjct: 759 NITKTEAVKVVKILESKLISSVKDLTPLLPKQLVLHREVELPNGCHFLYKVENKHHVSSC 818
Query: 760 VQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIKV 581
Q YYQ G++S+++NMLL+LF QII EPCF+ILR + QLGYIV SG+ + +GVQGL + V
Sbjct: 819 TQIYYQSGMQSTENNMLLELFTQIISEPCFNILRNEEQLGYIVFSGIRRNNGVQGLRVIV 878
Query: 580 QSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYAE 401
QSNK ++VE +I+ FM+ M +I M+ E FN HK+SL +L KP + Q+ I++ E
Sbjct: 879 QSNKSPEYVEKRIDLFMESMLKYITTMSDEEFNRHKESLATQLLEKPKMMSRQSGIYWLE 938
Query: 400 IVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPTSYKENVIGK 221
I QQYNFDR NIE +YLK I + I++FYK NS + KL I V+ T+ I +
Sbjct: 939 ISLQQYNFDRMNIEVAYLKTIMRNQIIDFYKNIVQTNSPQRHKLSIHVVSTAEGSTKIQE 998
Query: 220 ENS--------NEKQMI-----KITDLLEFKNNMTLFPLIEPYNQIVRKG 110
+ S +E ++I +I D+L+FK + L+PL +P+ I RKG
Sbjct: 999 KTSQITADVAKSEDEIIVEEPRRINDILQFKMSHPLYPLAKPFTNIPRKG 1048
>ref|XP_006610177.1| PREDICTED: insulin-degrading enzyme-like, partial [Apis dorsata]
Length = 360
Score = 281 bits (720), Expect = 5e-89
Identities = 154/351 (43%), Positives = 215/351 (61%), Gaps = 13/351 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KN++ ++P YY V+L+EQ W +DE L+A ++T EK+ENF+P LSK+H+E L H
Sbjct: 6 KNYKAEQPYQHAVYYLAVLLSEQIWMKDELLNALSYLTVEKVENFIPQFLSKIHMECLIH 65
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE +E +IE KL + I PLL + ++ R+I+L G +L+E + KY
Sbjct: 66 GNMTMSEAIETARLIESKLSNAIPHIIPLLSRQLILHREIKLEDGCHFLFEVQTKYHSSS 125
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q Y Q GL+S++ NMLL+L QI+ EPCF LRTK QLGYIV SG+ + +G QGL I
Sbjct: 126 CTQIYCQTGLQSTESNMLLELLAQILSEPCFTTLRTKEQLGYIVFSGVRRTNGAQGLRII 185
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS++ +VE +I+ F+ M +I +MT E FN HK+SL L KP + T ++IF+
Sbjct: 186 VQSDRHPKYVEQRIHTFLNSMLQNISSMTEEEFNAHKESLAIRRLEKPKQMTTLSSIFWN 245
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-------- 248
EIV+QQYNFDRANIE +YL+ I KE ILEFYK + +RKL + VI T
Sbjct: 246 EIVSQQYNFDRANIEVAYLRTITKEQILEFYKNILRNDI--QRKLSVHVISTLKDQNSNN 303
Query: 247 -----SYKENVIGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
S K E +N + KI D+L FK + L+ L +P+ + RKG
Sbjct: 304 EKAVESNKNTEQSNEINNTIEYKKIDDILSFKISQNLYSLPKPFTDVPRKG 354
>ref|XP_971897.2| PREDICTED: insulin-degrading enzyme [Tribolium castaneum]
Length = 1017
Score = 297 bits (760), Expect = 2e-88
Identities = 150/344 (43%), Positives = 231/344 (67%), Gaps = 6/344 (1%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KNF ++P YY +LTE WT+ E L+ + +T +KLE F+P +LSK+HIE L H
Sbjct: 672 KNFAAEQPYQHAVYYLAALLTEHSWTKQELLATTEQLTIDKLEAFIPQILSKMHIECLIH 731
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN + + L++V ++E +L+ + N ++PLLP+ +L +R+++L G Y+YE +N+ K
Sbjct: 732 GNANKEKALQLVQIVEDRLLSTLN-MSPLLPRQLLLNRELKLEDGCNYVYEVQNEVHKES 790
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
++ YYQ GL+S ++NM L+LF QI++EPCFDILRTK QLGYIV SG+ + +GVQGL I
Sbjct: 791 CIELYYQCGLQSKENNMKLELFAQIVQEPCFDILRTKEQLGYIVFSGIRRSNGVQGLRII 850
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS+K ++ +I EF+K M +++KNM+ E F H+++L L KP L TQTNIF+
Sbjct: 851 VQSDKHPVRLDERIEEFLKNMLSYLKNMSEEEFARHREALAAQRLEKPKQLSTQTNIFWG 910
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPTSYKENVIG 224
EI +QQY+FDRAN+E +YL+ + KEDI++FYK +EN+ ++KL + V+ S + G
Sbjct: 911 EITSQQYHFDRANVEVAYLRTLTKEDIIDFYKSLLEENAQFRKKLSVHVV--SMADGGAG 968
Query: 223 KENSNEKQM------IKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
K +++K+ + D+ FK++ + PL++PY I RKG
Sbjct: 969 KMAASDKEYTVDSKGTVVCDITVFKSSHEMHPLVQPYINITRKG 1012
>ref|XP_015116960.1| PREDICTED: insulin-degrading enzyme isoform X2 [Diachasma alloeum]
Length = 1020
Score = 296 bits (758), Expect = 3e-88
Identities = 158/353 (44%), Positives = 218/353 (61%), Gaps = 15/353 (4%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KN+ ++P YY V+L EQ WT++E L A IT E+LE F+P LLSK+H+E L H
Sbjct: 663 KNYGAEQPYQHAVYYLAVLLAEQVWTKEELLDASDDITVERLEAFVPQLLSKMHVESLVH 722
Query: 943 GNLLESETLEIVNMIEKKLI-----PSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNK 779
GNL ++E LE V ++E KL K + PLLP+ ++ R+I L +G +LYE NK
Sbjct: 723 GNLTKAEALETVRLVESKLTGDPTRQDKRRLIPLLPKQLMLYREIDLEEGCHFLYEVENK 782
Query: 778 YQKPIAVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQ 599
K + YYQ GL+S++ NM L+L QII EPCF +LRTK QLGYIV SG+ + +G Q
Sbjct: 783 LHKSSCTEVYYQSGLQSTESNMHLELLAQIISEPCFTVLRTKEQLGYIVFSGIRRTNGAQ 842
Query: 598 GLGIKVQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQT 419
GL + VQS++ +VE +I+ FM+ M + NM+ E FN HK SL L KP + T +
Sbjct: 843 GLRVIVQSDRHPQYVEERIDAFMESMLERLVNMSEEEFNRHKTSLAAQRLEKPKMMSTLS 902
Query: 418 NIFYAEIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT--- 248
+F++EI NQQYNFDRANIE YL I KE I+ F+K+ NS +RKL + VI T
Sbjct: 903 AVFWSEISNQQYNFDRANIEVGYLMTINKEQIISFFKEIVYNNSPTRRKLAVHVISTASG 962
Query: 247 -------SYKENVIGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
+ K+N + + KITD++ FK + +L+PL++PYN I RKG
Sbjct: 963 GAGCEKNTTKDNGEESKEARATSATKITDVIAFKASQSLYPLLKPYNNIPRKG 1015
>ref|XP_015116959.1| PREDICTED: insulin-degrading enzyme isoform X1 [Diachasma alloeum]
Length = 1022
Score = 296 bits (758), Expect = 3e-88
Identities = 158/353 (44%), Positives = 218/353 (61%), Gaps = 15/353 (4%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KN+ ++P YY V+L EQ WT++E L A IT E+LE F+P LLSK+H+E L H
Sbjct: 665 KNYGAEQPYQHAVYYLAVLLAEQVWTKEELLDASDDITVERLEAFVPQLLSKMHVESLVH 724
Query: 943 GNLLESETLEIVNMIEKKLI-----PSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNK 779
GNL ++E LE V ++E KL K + PLLP+ ++ R+I L +G +LYE NK
Sbjct: 725 GNLTKAEALETVRLVESKLTGDPTRQDKRRLIPLLPKQLMLYREIDLEEGCHFLYEVENK 784
Query: 778 YQKPIAVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQ 599
K + YYQ GL+S++ NM L+L QII EPCF +LRTK QLGYIV SG+ + +G Q
Sbjct: 785 LHKSSCTEVYYQSGLQSTESNMHLELLAQIISEPCFTVLRTKEQLGYIVFSGIRRTNGAQ 844
Query: 598 GLGIKVQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQT 419
GL + VQS++ +VE +I+ FM+ M + NM+ E FN HK SL L KP + T +
Sbjct: 845 GLRVIVQSDRHPQYVEERIDAFMESMLERLVNMSEEEFNRHKTSLAAQRLEKPKMMSTLS 904
Query: 418 NIFYAEIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT--- 248
+F++EI NQQYNFDRANIE YL I KE I+ F+K+ NS +RKL + VI T
Sbjct: 905 AVFWSEISNQQYNFDRANIEVGYLMTINKEQIISFFKEIVYNNSPTRRKLAVHVISTASG 964
Query: 247 -------SYKENVIGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
+ K+N + + KITD++ FK + +L+PL++PYN I RKG
Sbjct: 965 GAGCEKNTTKDNGEESKEARATSATKITDVIAFKASQSLYPLLKPYNNIPRKG 1017
>gb|KOC65772.1| Insulin-degrading enzyme, partial [Habropoda laboriosa]
Length = 393
Score = 280 bits (715), Expect = 7e-88
Identities = 153/349 (43%), Positives = 214/349 (61%), Gaps = 11/349 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
+N + ++P YY V+L EQ W +DE L A + +T E++E F+P L+K+H+E L H
Sbjct: 41 ENSQAEQPYQHAVYYLVVLLAEQVWMKDELLEATKQLTVERVEQFIPQFLNKIHMECLIH 100
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE LE +IE KL + I PLLP+ ++ R+I+L G +L+E NKY
Sbjct: 101 GNMTFSEALETGRLIESKLSSTIPQIIPLLPRQLISQREIKLEDGCHFLFEVTNKYHSSS 160
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ+G+ES + NMLL+L QI+ EPCF LRTK QLGYIV SG+ K +G QGL I
Sbjct: 161 CTQVYYQIGMESIESNMLLELLAQILSEPCFTTLRTKEQLGYIVFSGVRKTNGTQGLRII 220
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS+K +VE +IN F+ M +I ++T E FN HK++L L KP + T + +F+
Sbjct: 221 VQSDKHPKYVEQRINIFLSSMLQYISSITEEEFNAHKEALAIRRLEKPKKMTTLSTVFWN 280
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-----SYK 239
EI QQYNFDRANIE +YL+ + KE IL+FYK + + KL + V+ T S
Sbjct: 281 EIATQQYNFDRANIEVAYLRTLIKEQILKFYKDMLQNDI--QHKLSVHVLSTIKDSKSEN 338
Query: 238 ENVIGK------ENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
EN I + +N + KI D+L FK + L+PL++P+N I RKG
Sbjct: 339 ENAIEPNENIQLDETNTIEYKKIDDVLSFKISQCLYPLLKPFNDIPRKG 387
>ref|XP_008554389.1| PREDICTED: insulin-degrading enzyme isoform X2 [Microplitis
demolitor]
Length = 1011
Score = 294 bits (753), Expect = 1e-87
Identities = 157/354 (44%), Positives = 217/354 (61%), Gaps = 17/354 (4%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KNFE +P YY V+LTEQ W++DE L A +++T ++LE F+P LLSK HIE L H
Sbjct: 652 KNFEADQPYQHAVYYLAVLLTEQGWSKDELLEAIEYLTFDRLEQFIPQLLSKTHIECLIH 711
Query: 943 GNLLESETLEIVNMIEKKLIPS------KNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRN 782
GNL E+E LE + M+E +L I PLLP+ L R+I L G +LYE N
Sbjct: 712 GNLTEAEALETIKMVENQLTKDPLDDNKSKIIVPLLPKQYLLHREISLDNGSHFLYEIEN 771
Query: 781 KYQKPIAVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGV 602
K K + YYQVGL+S++ NM L+L QII EP FD+LRT+ QLGYIV SG+ + +GV
Sbjct: 772 KLHKSSCTEIYYQVGLQSTESNMHLELLGQIISEPFFDVLRTQEQLGYIVFSGIRRGNGV 831
Query: 601 QGLGIKVQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQ 422
QGL I +Q ++ ++E +I F++ ++N I NM+ E FN HK SL L KP + T
Sbjct: 832 QGLRIIIQGDRHPQYLEERIEAFIESVQNRIVNMSEEEFNRHKTSLANQRLEKPKKMTTL 891
Query: 421 TNIFYAEIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-- 248
+ IF++EI N+QYNFDRANIE +YL+ I K IL+FY + + S +RKL + V+ T
Sbjct: 892 SAIFWSEITNRQYNFDRANIEVAYLRTITKSQILDFYNEKIKQQSPFRRKLSLHVVSTAP 951
Query: 247 ---------SYKENVIGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRK 113
S E+ N IKITD+L FK + +L+P+++P+ I RK
Sbjct: 952 GGAGHTEKSSQDSVTTTTEDDNTSSPIKITDILSFKTSQSLYPIVKPFINISRK 1005
>ref|XP_008554388.1| PREDICTED: insulin-degrading enzyme isoform X1 [Microplitis
demolitor]
Length = 1025
Score = 294 bits (753), Expect = 2e-87
Identities = 157/354 (44%), Positives = 217/354 (61%), Gaps = 17/354 (4%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KNFE +P YY V+LTEQ W++DE L A +++T ++LE F+P LLSK HIE L H
Sbjct: 666 KNFEADQPYQHAVYYLAVLLTEQGWSKDELLEAIEYLTFDRLEQFIPQLLSKTHIECLIH 725
Query: 943 GNLLESETLEIVNMIEKKLIPS------KNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRN 782
GNL E+E LE + M+E +L I PLLP+ L R+I L G +LYE N
Sbjct: 726 GNLTEAEALETIKMVENQLTKDPLDDNKSKIIVPLLPKQYLLHREISLDNGSHFLYEIEN 785
Query: 781 KYQKPIAVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGV 602
K K + YYQVGL+S++ NM L+L QII EP FD+LRT+ QLGYIV SG+ + +GV
Sbjct: 786 KLHKSSCTEIYYQVGLQSTESNMHLELLGQIISEPFFDVLRTQEQLGYIVFSGIRRGNGV 845
Query: 601 QGLGIKVQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQ 422
QGL I +Q ++ ++E +I F++ ++N I NM+ E FN HK SL L KP + T
Sbjct: 846 QGLRIIIQGDRHPQYLEERIEAFIESVQNRIVNMSEEEFNRHKTSLANQRLEKPKKMTTL 905
Query: 421 TNIFYAEIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-- 248
+ IF++EI N+QYNFDRANIE +YL+ I K IL+FY + + S +RKL + V+ T
Sbjct: 906 SAIFWSEITNRQYNFDRANIEVAYLRTITKSQILDFYNEKIKQQSPFRRKLSLHVVSTAP 965
Query: 247 ---------SYKENVIGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRK 113
S E+ N IKITD+L FK + +L+P+++P+ I RK
Sbjct: 966 GGAGHTEKSSQDSVTTTTEDDNTSSPIKITDILSFKTSQSLYPIVKPFINISRK 1019
>ref|XP_014206136.1| insulin-degrading enzyme isoform X2 [Copidosoma floridanum]
Length = 1008
Score = 293 bits (750), Expect = 4e-87
Identities = 147/346 (42%), Positives = 223/346 (64%), Gaps = 8/346 (2%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KNFE ++P +YY V+L+E W ++E L+ +T +K++ F+P +SK+HIE L H
Sbjct: 658 KNFEAEQPYQHAAYYLAVLLSEHVWVKNELLNTCSMLTADKMKQFIPLFMSKMHIECLIH 717
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE + ++E K + S + PLLP+ M+ R++QLP+G YLYE NK+ K
Sbjct: 718 GNVTRSEASQTAKLVESKFVNSVKDLMPLLPRQMVPYRELQLPQGCHYLYEAENKHHKSS 777
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
+ YYQ G++S++ NMLL+L QII EPCF+ILRTK QLGYIV SG+ + GVQGL I
Sbjct: 778 CTEVYYQSGMQSTESNMLLELISQIISEPCFNILRTKEQLGYIVFSGIRRADGVQGLKIL 837
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS FVE +I+ F +M+ HI M E FN+HK+SL L KP L Q++I++
Sbjct: 838 VQSGHHPQFVERRIDSFTSQMKEHIATMPDEEFNKHKESLATRRLEKPKTLSKQSSIYWN 897
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-----SYK 239
EI QQYNFDR +IE +YL+ I ++ I++FY+ D S K+ + I V+ T + +
Sbjct: 898 EISMQQYNFDRTSIEVAYLRTITRDQIVKFYEDIIDGKS--KKNICIHVVSTVEDGQAKQ 955
Query: 238 ENVIGKE---NSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
+ +G++ S+ +++ +I D+L+FK N L+P+++P+N + RKG
Sbjct: 956 DTPLGEDGVATSSVEEVQRIDDILQFKTNHPLYPILQPFNNVPRKG 1001
>ref|XP_014206133.1| insulin-degrading enzyme isoform X1 [Copidosoma floridanum]
ref|XP_014206134.1| insulin-degrading enzyme isoform X1 [Copidosoma floridanum]
ref|XP_023248111.1| insulin-degrading enzyme isoform X1 [Copidosoma floridanum]
Length = 1009
Score = 293 bits (750), Expect = 4e-87
Identities = 147/346 (42%), Positives = 223/346 (64%), Gaps = 8/346 (2%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KNFE ++P +YY V+L+E W ++E L+ +T +K++ F+P +SK+HIE L H
Sbjct: 659 KNFEAEQPYQHAAYYLAVLLSEHVWVKNELLNTCSMLTADKMKQFIPLFMSKMHIECLIH 718
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE + ++E K + S + PLLP+ M+ R++QLP+G YLYE NK+ K
Sbjct: 719 GNVTRSEASQTAKLVESKFVNSVKDLMPLLPRQMVPYRELQLPQGCHYLYEAENKHHKSS 778
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
+ YYQ G++S++ NMLL+L QII EPCF+ILRTK QLGYIV SG+ + GVQGL I
Sbjct: 779 CTEVYYQSGMQSTESNMLLELISQIISEPCFNILRTKEQLGYIVFSGIRRADGVQGLKIL 838
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS FVE +I+ F +M+ HI M E FN+HK+SL L KP L Q++I++
Sbjct: 839 VQSGHHPQFVERRIDSFTSQMKEHIATMPDEEFNKHKESLATRRLEKPKTLSKQSSIYWN 898
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-----SYK 239
EI QQYNFDR +IE +YL+ I ++ I++FY+ D S K+ + I V+ T + +
Sbjct: 899 EISMQQYNFDRTSIEVAYLRTITRDQIVKFYEDIIDGKS--KKNICIHVVSTVEDGQAKQ 956
Query: 238 ENVIGKE---NSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
+ +G++ S+ +++ +I D+L+FK N L+P+++P+N + RKG
Sbjct: 957 DTPLGEDGVATSSVEEVQRIDDILQFKTNHPLYPILQPFNNVPRKG 1002
>gb|KOC65774.1| Insulin-degrading enzyme, partial [Habropoda laboriosa]
Length = 393
Score = 278 bits (710), Expect = 4e-87
Identities = 152/349 (43%), Positives = 214/349 (61%), Gaps = 11/349 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
+N + ++P YY V+L EQ W +DE L A + +T E++E F+P L+K+H+E L H
Sbjct: 41 ENSQAEQPYQHAVYYLVVLLAEQVWMKDELLEATKQLTVERVEQFIPQFLNKIHMECLIH 100
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE LE +IE KL + I PLLP+ ++ R+I+L G +L+E NKY
Sbjct: 101 GNMTFSEALETGRLIESKLSSTIPQIIPLLPRQLISQREIKLEDGCHFLFEVTNKYHSSS 160
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ+G+ES + NMLL+L QI+ EPCF LRTK QLGYIV SG+ K +G QGL I
Sbjct: 161 CTQVYYQIGMESIESNMLLELLAQILSEPCFTTLRTKEQLGYIVFSGVRKTNGTQGLRII 220
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS+K +VE +IN F+ M +I ++T E FN HK++L L KP + T + +F+
Sbjct: 221 VQSDKHPKYVEQRINIFLSSMLQYISSITEEEFNAHKEALAIRRLEKPKKMTTLSTVFWN 280
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-----SYK 239
EI QQYNFDRANIE +YL+ + KE IL+FYK + + KL + V+ T S
Sbjct: 281 EIATQQYNFDRANIEVAYLRTLIKEQILKFYKDMLQNDI--QHKLSVHVLSTIKDSKSEN 338
Query: 238 ENVIGK------ENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKG 110
EN I + +N + KI D+L FK + L+PL++P++ I RKG
Sbjct: 339 ENAIEPNENIQLDETNTIEYKKIDDVLSFKISQCLYPLLKPFSDIPRKG 387
>ref|XP_003701355.1| PREDICTED: insulin-degrading enzyme [Megachile rotundata]
Length = 1015
Score = 289 bits (739), Expect = 1e-85
Identities = 157/351 (44%), Positives = 220/351 (62%), Gaps = 12/351 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KNFET++P YY V+L+EQ W +DE L A +T E+L+ F+P LS++HIE L H
Sbjct: 662 KNFETEQPYQHAVYYLAVLLSEQVWMKDELLQATSQLTAERLQQFIPQFLSQIHIECLIH 721
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE ++ V IE KL + + PLLP+ ++ R+I+L G +L+E +NK+
Sbjct: 722 GNMTMSEAIDTVRKIESKLTTTFPHVTPLLPRQLILYREIKLEDGHHFLFEVQNKFHSSS 781
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q Y+Q GL+S++ NMLL+L Q+I EPCF ILRTK QLGYIV SG+ + +G QGL I
Sbjct: 782 CTQVYFQTGLQSTESNMLLELLAQLISEPCFTILRTKEQLGYIVYSGVRRTNGAQGLRII 841
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS++D +VE KIN F+ M HI +M+ E F HK+SL L KP + T + IF+
Sbjct: 842 VQSDRDPKYVEQKINSFLNSMLQHISSMSDEEFERHKESLAVRRLEKPKKITTLSAIFWN 901
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT----SYKE 236
EI QQYNFDRANIE +YL+ I +E IL+FY++ S + KL + VI T E
Sbjct: 902 EISIQQYNFDRANIEVAYLRTITREQILKFYEEML--QSDIQHKLSVHVISTVKVSESVE 959
Query: 235 NVIGKEN--------SNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKGA 107
N I + N N + KI D++ FK + +L+PL++P++ I RKGA
Sbjct: 960 NDIMESNEDTSPSDAENATEYKKIDDIISFKISQSLYPLLKPFSDIPRKGA 1010
>ref|XP_024227556.1| insulin-degrading enzyme isoform X4 [Bombus impatiens]
Length = 984
Score = 287 bits (734), Expect = 5e-85
Identities = 153/350 (43%), Positives = 222/350 (63%), Gaps = 11/350 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KN++ ++P YY V+L+EQ W +DE L+A +T E+++NF+P L+K+H+E L H
Sbjct: 632 KNYKAEQPYQHAVYYLAVLLSEQIWMKDELLNATSHLTVERVQNFIPQFLNKIHMECLIH 691
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE +E IE KL + I PLL + ++ R+I+L G +L+E + K+
Sbjct: 692 GNITMSEAIETAKSIESKLSNAVPHIVPLLSRQLILHREIKLEDGCQFLFEVKTKFHSNS 751
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ GL+S++ NMLL+L QI+ EPCF LRTK QLGYIV SG+ + +G QGL I
Sbjct: 752 CTQVYYQTGLQSTESNMLLELLAQILSEPCFTTLRTKEQLGYIVFSGVRRTNGAQGLRII 811
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS++ +VE +IN F+ M +I +MT E FN HK+SL L KP + T + IF++
Sbjct: 812 VQSDRHPKYVEQRINAFLNSMLQYIPSMTKEEFNAHKESLAIRRLEKPKQMTTLSAIFWS 871
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-----SYK 239
EI++QQYNFDRANIE +YLK I +E IL+FYK+ F + +RKL + V+ T
Sbjct: 872 EIISQQYNFDRANIEVAYLKTITQEQILKFYKEIFQNDI--QRKLSVHVLSTLKDVKLED 929
Query: 238 ENV------IGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKGA 107
ENV I + +N + KI D++ FK + L+PL++P++ I RKGA
Sbjct: 930 ENVMESNEYISSDGTNNIEPKKIDDIISFKISQCLYPLLKPFSDIPRKGA 979
>ref|XP_012172345.2| LOW QUALITY PROTEIN: insulin-degrading enzyme [Bombus terrestris]
Length = 1019
Score = 287 bits (735), Expect = 6e-85
Identities = 154/350 (44%), Positives = 222/350 (63%), Gaps = 11/350 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KN++ ++P YY V+L+EQ W +DE L+A +T E+++NF+P LSK+H+E L H
Sbjct: 667 KNYKAEQPYQHAVYYLAVLLSEQIWMKDELLNATSHLTVERVQNFIPQFLSKIHMECLMH 726
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE +E IE KL + I PLL + ++ R+I+L G +L+E + K+
Sbjct: 727 GNITMSEAIETAKSIESKLSNAVPHIVPLLSRQLILHREIKLEDGCHFLFEVKTKFHSNS 786
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ GL+S++ NMLL+L QI+ EPCF LRTK QLGYIV SG+ + + QGL I
Sbjct: 787 CTQVYYQTGLQSTESNMLLELLAQILSEPCFTTLRTKEQLGYIVFSGVRRTNDAQGLRII 846
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS++ +VE +IN F+ M +I +MT E FN HK+SL L KP + T + IF++
Sbjct: 847 VQSDRHPKYVEQRINAFLNSMLQYIPSMTKEEFNAHKESLAIRRLEKPKQMTTLSAIFWS 906
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-----SYK 239
EI++QQYNFDRANIE +YLK I +E IL+FYK+ F S ++RKL + V+ T
Sbjct: 907 EIISQQYNFDRANIEVAYLKTITQEQILKFYKEIF--QSDNQRKLSVHVLSTLKDVKLED 964
Query: 238 ENV------IGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKGA 107
ENV I + +N + KI D++ FK + L+PL++P++ I RKGA
Sbjct: 965 ENVMESNEYISSDGTNNIEPXKIDDIISFKISQCLYPLLKPFSDIPRKGA 1014
>ref|XP_024227555.1| insulin-degrading enzyme isoform X3 [Bombus impatiens]
Length = 997
Score = 287 bits (734), Expect = 6e-85
Identities = 153/350 (43%), Positives = 222/350 (63%), Gaps = 11/350 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KN++ ++P YY V+L+EQ W +DE L+A +T E+++NF+P L+K+H+E L H
Sbjct: 645 KNYKAEQPYQHAVYYLAVLLSEQIWMKDELLNATSHLTVERVQNFIPQFLNKIHMECLIH 704
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE +E IE KL + I PLL + ++ R+I+L G +L+E + K+
Sbjct: 705 GNITMSEAIETAKSIESKLSNAVPHIVPLLSRQLILHREIKLEDGCQFLFEVKTKFHSNS 764
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ GL+S++ NMLL+L QI+ EPCF LRTK QLGYIV SG+ + +G QGL I
Sbjct: 765 CTQVYYQTGLQSTESNMLLELLAQILSEPCFTTLRTKEQLGYIVFSGVRRTNGAQGLRII 824
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS++ +VE +IN F+ M +I +MT E FN HK+SL L KP + T + IF++
Sbjct: 825 VQSDRHPKYVEQRINAFLNSMLQYIPSMTKEEFNAHKESLAIRRLEKPKQMTTLSAIFWS 884
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-----SYK 239
EI++QQYNFDRANIE +YLK I +E IL+FYK+ F + +RKL + V+ T
Sbjct: 885 EIISQQYNFDRANIEVAYLKTITQEQILKFYKEIFQNDI--QRKLSVHVLSTLKDVKLED 942
Query: 238 ENV------IGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKGA 107
ENV I + +N + KI D++ FK + L+PL++P++ I RKGA
Sbjct: 943 ENVMESNEYISSDGTNNIEPKKIDDIISFKISQCLYPLLKPFSDIPRKGA 992
>ref|XP_024227554.1| insulin-degrading enzyme isoform X2 [Bombus impatiens]
Length = 999
Score = 287 bits (734), Expect = 6e-85
Identities = 153/350 (43%), Positives = 222/350 (63%), Gaps = 11/350 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KN++ ++P YY V+L+EQ W +DE L+A +T E+++NF+P L+K+H+E L H
Sbjct: 647 KNYKAEQPYQHAVYYLAVLLSEQIWMKDELLNATSHLTVERVQNFIPQFLNKIHMECLIH 706
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE +E IE KL + I PLL + ++ R+I+L G +L+E + K+
Sbjct: 707 GNITMSEAIETAKSIESKLSNAVPHIVPLLSRQLILHREIKLEDGCQFLFEVKTKFHSNS 766
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ GL+S++ NMLL+L QI+ EPCF LRTK QLGYIV SG+ + +G QGL I
Sbjct: 767 CTQVYYQTGLQSTESNMLLELLAQILSEPCFTTLRTKEQLGYIVFSGVRRTNGAQGLRII 826
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS++ +VE +IN F+ M +I +MT E FN HK+SL L KP + T + IF++
Sbjct: 827 VQSDRHPKYVEQRINAFLNSMLQYIPSMTKEEFNAHKESLAIRRLEKPKQMTTLSAIFWS 886
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-----SYK 239
EI++QQYNFDRANIE +YLK I +E IL+FYK+ F + +RKL + V+ T
Sbjct: 887 EIISQQYNFDRANIEVAYLKTITQEQILKFYKEIFQNDI--QRKLSVHVLSTLKDVKLED 944
Query: 238 ENV------IGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKGA 107
ENV I + +N + KI D++ FK + L+PL++P++ I RKGA
Sbjct: 945 ENVMESNEYISSDGTNNIEPKKIDDIISFKISQCLYPLLKPFSDIPRKGA 994
>ref|XP_012248321.2| insulin-degrading enzyme isoform X1 [Bombus impatiens]
Length = 1019
Score = 287 bits (734), Expect = 8e-85
Identities = 153/350 (43%), Positives = 222/350 (63%), Gaps = 11/350 (3%)
Frame = -2
Query: 1123 KNFETKEPQSQVSYYNNVVLTEQFWTEDERLSAFQFITKEKLENFLPYLLSKLHIEGLFH 944
KN++ ++P YY V+L+EQ W +DE L+A +T E+++NF+P L+K+H+E L H
Sbjct: 667 KNYKAEQPYQHAVYYLAVLLSEQIWMKDELLNATSHLTVERVQNFIPQFLNKIHMECLIH 726
Query: 943 GNLLESETLEIVNMIEKKLIPSKNGIAPLLPQLMLQSRQIQLPKGQVYLYEYRNKYQKPI 764
GN+ SE +E IE KL + I PLL + ++ R+I+L G +L+E + K+
Sbjct: 727 GNITMSEAIETAKSIESKLSNAVPHIVPLLSRQLILHREIKLEDGCQFLFEVKTKFHSNS 786
Query: 763 AVQFYYQVGLESSKDNMLLQLFEQIIREPCFDILRTKHQLGYIVGSGLFKKHGVQGLGIK 584
Q YYQ GL+S++ NMLL+L QI+ EPCF LRTK QLGYIV SG+ + +G QGL I
Sbjct: 787 CTQVYYQTGLQSTESNMLLELLAQILSEPCFTTLRTKEQLGYIVFSGVRRTNGAQGLRII 846
Query: 583 VQSNKDVDFVENKINEFMKEMENHIKNMTGEVFNEHKKSLEFSMLAKPINLHTQTNIFYA 404
VQS++ +VE +IN F+ M +I +MT E FN HK+SL L KP + T + IF++
Sbjct: 847 VQSDRHPKYVEQRINAFLNSMLQYIPSMTKEEFNAHKESLAIRRLEKPKQMTTLSAIFWS 906
Query: 403 EIVNQQYNFDRANIESSYLKNIKKEDILEFYKKYFDENSADKRKLIIRVIPT-----SYK 239
EI++QQYNFDRANIE +YLK I +E IL+FYK+ F + +RKL + V+ T
Sbjct: 907 EIISQQYNFDRANIEVAYLKTITQEQILKFYKEIFQNDI--QRKLSVHVLSTLKDVKLED 964
Query: 238 ENV------IGKENSNEKQMIKITDLLEFKNNMTLFPLIEPYNQIVRKGA 107
ENV I + +N + KI D++ FK + L+PL++P++ I RKGA
Sbjct: 965 ENVMESNEYISSDGTNNIEPKKIDDIISFKISQCLYPLLKPFSDIPRKGA 1014