BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon22_contig00028546
         (4353 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_020262391.1| LOW QUALITY PROTEIN: DNA topoisomerase 2-lik...  2140   0.0  
gb|ONK71489.1| uncharacterized protein A4U43_C04F9180 [Asparagus...  2062   0.0  
ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guine...  1950   0.0  
gb|OAY66581.1| DNA topoisomerase 2 [Ananas comosus]                  1949   0.0  
ref|XP_009399445.1| PREDICTED: DNA topoisomerase 2-like [Musa ac...  1917   0.0  
ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1909   0.0  
ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform ...  1908   0.0  
ref|XP_009402954.1| PREDICTED: DNA topoisomerase 2-like [Musa ac...  1906   0.0  
ref|XP_020693654.1| DNA topoisomerase 2 [Dendrobium catenatum] >...  1901   0.0  
ref|XP_020577441.1| DNA topoisomerase 2 [Phalaenopsis equestris]     1882   0.0  
gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]               1862   0.0  
ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]  1847   0.0  
emb|CDP07797.1| unnamed protein product [Coffea canephora]           1836   0.0  
ref|XP_008779357.2| PREDICTED: DNA topoisomerase 2 [Phoenix dact...  1834   0.0  
gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]       1817   0.0  
ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]         1817   0.0  
ref|XP_007009327.2| PREDICTED: DNA topoisomerase 2 [Theobroma ca...  1814   0.0  
ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus g...  1798   0.0  
ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Z...  1780   0.0  
gb|OWM78385.1| hypothetical protein CDL15_Pgr016109 [Punica gran...  1776   0.0  

>ref|XP_020262391.1| LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Asparagus officinalis]
          Length = 1489

 Score = 2140 bits (5544), Expect = 0.0
 Identities = 1097/1447 (75%), Positives = 1195/1447 (82%), Gaps = 7/1447 (0%)
 Frame = +2

Query: 2    GGGKKTIEEV-YQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYK 178
            GGGKKTIEEV ++KKTQLEHILLRPDTYIGS+EKHTA LWV+E+GEM +RP+SYVPGLYK
Sbjct: 25   GGGKKTIEEVLFRKKTQLEHILLRPDTYIGSVEKHTANLWVYENGEMVHRPVSYVPGLYK 84

Query: 179  IFDEILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFG 358
            IFDEILVNAADNKQRDP+MD VKVDIDPE NLISVYNNGDGVP+EIHQEEGVYVPEMIFG
Sbjct: 85   IFDEILVNAADNKQRDPSMDTVKVDIDPEQNLISVYNNGDGVPVEIHQEEGVYVPEMIFG 144

Query: 359  HLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSD 538
            HLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVF+ENMGKKS+
Sbjct: 145  HLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFTENMGKKSE 204

Query: 539  PSITKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTR 718
            P+ITKCK GENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVD+AGTLGK VKVELNG R
Sbjct: 205  PTITKCKDGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGTLGKSVKVELNGQR 264

Query: 719  VPVKTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIK 898
            +PVK F+DYV+LYLKSA+K R+EPLP I EK N+RWEV VSLSEGQFQQVSFVNGI+TIK
Sbjct: 265  LPVKVFSDYVNLYLKSASKGRNEPLPSIGEKVNDRWEVYVSLSEGQFQQVSFVNGISTIK 324

Query: 899  GGTHVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLT 1078
            GGTHV+YVTSQI                         LWVFVN LIDNPAFDSQTKETLT
Sbjct: 325  GGTHVDYVTSQIANHVMAVVNKKNKNANLKAHNVKNHLWVFVNALIDNPAFDSQTKETLT 384

Query: 1079 TRQGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDD 1255
            TRQGSFGSKCELS  FLKKVDKSGIVETLLSWADFKQSKELKKTDG+KRQ +  IPKLDD
Sbjct: 385  TRQGSFGSKCELSQAFLKKVDKSGIVETLLSWADFKQSKELKKTDGAKRQKITGIPKLDD 444

Query: 1256 ANDAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQ 1435
            ANDAGGKNS+KCTLILTEGDSAKALAVAGVSEVGR+ YGVFPLKGKLLNVREASLKQIMQ
Sbjct: 445  ANDAGGKNSEKCTLILTEGDSAKALAVAGVSEVGRDHYGVFPLKGKLLNVREASLKQIMQ 504

Query: 1436 NAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK 1615
            N EIQ++KQILGLQ  K+YDSVKGLRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
Sbjct: 505  NDEIQHLKQILGLQQDKKYDSVKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK 564

Query: 1616 VKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKE 1795
            + GFM EFITPIVKAS KNG VLSFY+MPEYEAWKESLNGNA+GWTIKYYKGLGTST+KE
Sbjct: 565  INGFMEEFITPIVKASRKNGEVLSFYSMPEYEAWKESLNGNASGWTIKYYKGLGTSTSKE 624

Query: 1796 GKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKY 1975
            GKEYF+Q+RKHKKSF+W+D+QDGE+IELAFSKKKIEARKNWLRQFE GTYLD + E+I Y
Sbjct: 625  GKEYFRQIRKHKKSFIWSDDQDGEAIELAFSKKKIEARKNWLRQFEPGTYLDQEGEKITY 684

Query: 1976 SDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHS 2155
            SDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN +KEAKVAQFSGYVSEHS
Sbjct: 685  SDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNFVKEAKVAQFSGYVSEHS 744

Query: 2156 AYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITR 2335
            AYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRN+GGKDAASGRYIYTCLSPITR
Sbjct: 745  AYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNRGGKDAASGRYIYTCLSPITR 804

Query: 2336 FLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVAN 2515
            +LFPK            GQSIEP+WY+PIIPMVL+NGSEGIGTGWSSYVPNYNPRDV+AN
Sbjct: 805  YLFPKDDDLLLDYLDEDGQSIEPSWYVPIIPMVLINGSEGIGTGWSSYVPNYNPRDVIAN 864

Query: 2516 VRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSW 2695
            VRRLLNDEPM+PM+PWYRGF+G+I KSA+KETGVTYTISGIIEEVD +TLRITELPIRSW
Sbjct: 865  VRRLLNDEPMQPMDPWYRGFQGIIWKSAEKETGVTYTISGIIEEVDSSTLRITELPIRSW 924

Query: 2696 TADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXX 2875
            T +YNEFL+AMM GTDKFKEPFIQDK+AYNDD  VHFE++LSE+NM  AKQEG       
Sbjct: 925  TLEYNEFLEAMMNGTDKFKEPFIQDKKAYNDDTTVHFEIMLSEQNMEVAKQEGLEKKFKL 984

Query: 2876 XXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXX 3055
               IST+NMHLFD +G IKKYDTPEQILEDFFHLRL+FYEKR+K+               
Sbjct: 985  TNTISTTNMHLFDPSGVIKKYDTPEQILEDFFHLRLEFYEKRRKILLDNLEFDLLKLDNK 1044

Query: 3056 VRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXX 3235
            VRFIL VV+GEIIVNNR+R DLFLELHQKGFTPFPKKTKGIDAAIAGATV+T        
Sbjct: 1045 VRFILGVVRGEIIVNNRKRVDLFLELHQKGFTPFPKKTKGIDAAIAGATVETEENEEESP 1104

Query: 3236 XTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDA 3415
              VKG VKASDYEYLLS++IG+LTLEKVQ LCADK++L+HELE LRSTS + LWMRDLDA
Sbjct: 1105 EMVKGAVKASDYEYLLSLAIGTLTLEKVQALCADKERLEHELEMLRSTSPRALWMRDLDA 1164

Query: 3416 LEKQLDELDQKDVEAANMQEKIRRR-NTGAAVPSKAPKKPRKNNAIKGPTVAANDADADV 3592
            LE QLDE DQ+D  AA  ++++R + N GAAV  KAPK  +KNN  K  ++AA +  A V
Sbjct: 1165 LEAQLDEHDQQDAVAAKTRQEMRAKINKGAAVSRKAPKPLKKNNTTK--SIAATETGATV 1222

Query: 3593 GTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXXKDRLAAYNLDSSPDQ 3772
            G+TSTA +AGN                 AKK TVV          KDRLAAYNLDSSPDQ
Sbjct: 1223 GSTSTATEAGNVTEVAKPKPRGGQKKAPAKKATVVDSDDDEVLELKDRLAAYNLDSSPDQ 1282

Query: 3773 TFMETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDG-DDGDFQM 3949
            T METE+V +     K  +KRA  RK KST+TIS           P I EDG DD DF+M
Sbjct: 1283 TSMETEAVGK-----KEANKRAAARKPKSTLTISDDDDDMNAEEMPTIVEDGDDDADFEM 1337

Query: 3950 VEV---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKPVVNASP 4120
            +E                                   +GKSL+SQK ITD+LKPV NASP
Sbjct: 1338 MEAAPKGKKGGAGRKPANAKAKGTTTMTTARKRGGGAKGKSLLSQKAITDMLKPVENASP 1397

Query: 4121 EKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEMNEVPVARNRPKREN 4300
            EKKVRKMRESPFNKKSGSVLGRA G + ESEGS+ S  SVNLE   + V V RN PKREN
Sbjct: 1398 EKKVRKMRESPFNKKSGSVLGRAGGSMTESEGSVGSLSSVNLEAGRDVVQVTRNLPKREN 1457

Query: 4301 RSKVQYV 4321
            R KV YV
Sbjct: 1458 RKKVTYV 1464


>gb|ONK71489.1| uncharacterized protein A4U43_C04F9180 [Asparagus officinalis]
          Length = 1419

 Score = 2062 bits (5342), Expect = 0.0
 Identities = 1058/1401 (75%), Positives = 1151/1401 (82%), Gaps = 6/1401 (0%)
 Frame = +2

Query: 137  MANRPISYVPGLYKIFDEILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEI 316
            M +RP+SYVPGLYKIFDEILVNAADNKQRDP+MD VKVDIDPE NLISVYNNGDGVP+EI
Sbjct: 1    MVHRPVSYVPGLYKIFDEILVNAADNKQRDPSMDTVKVDIDPEQNLISVYNNGDGVPVEI 60

Query: 317  HQEEGVYVPEMIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKK 496
            HQEEGVYVPEMIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKK
Sbjct: 61   HQEEGVYVPEMIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKK 120

Query: 497  YKQVFSENMGKKSDPSITKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAG 676
            YKQVF+ENMGKKS+P+ITKCK GENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVD+AG
Sbjct: 121  YKQVFTENMGKKSEPTITKCKDGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAG 180

Query: 677  TLGKGVKVELNGTRVPVKTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQ 856
            TLGK VKVELNG R+PVK F+DYV+LYLKSA+K R+EPLP I EK N+RWEV VSLSEGQ
Sbjct: 181  TLGKSVKVELNGQRLPVKVFSDYVNLYLKSASKGRNEPLPSIGEKVNDRWEVYVSLSEGQ 240

Query: 857  FQQVSFVNGINTIKGGTHVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLI 1036
            FQQVSFVNGI+TIKGGTHV+YVTSQI                         LWVFVN LI
Sbjct: 241  FQQVSFVNGISTIKGGTHVDYVTSQIANHVMAVVNKKNKNANLKAHNVKNHLWVFVNALI 300

Query: 1037 DNPAFDSQTKETLTTRQGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDG 1216
            DNPAFDSQTKETLTTRQGSFGSKCELS  FLKKVDKSGIVETLLSWADFKQSKELKKTDG
Sbjct: 301  DNPAFDSQTKETLTTRQGSFGSKCELSQAFLKKVDKSGIVETLLSWADFKQSKELKKTDG 360

Query: 1217 SKRQNVN-IPKLDDANDAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGK 1393
            +KRQ +  IPKLDDANDAGGKNS+KCTLILTEGDSAKALAVAGVSEVGR+ YGVFPLKGK
Sbjct: 361  AKRQKITGIPKLDDANDAGGKNSEKCTLILTEGDSAKALAVAGVSEVGRDHYGVFPLKGK 420

Query: 1394 LLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGL 1573
            LLNVREASLKQIMQN EIQ++KQILGLQ  K+YDSVKGLRYG LMIMTDQDHDGSHIKGL
Sbjct: 421  LLNVREASLKQIMQNDEIQHLKQILGLQQDKKYDSVKGLRYGHLMIMTDQDHDGSHIKGL 480

Query: 1574 LINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWT 1753
            LINFIHSFWPSLLK+ GFM EFITPIVKAS KNG VLSFY+MPEYEAWKESLNGNA+GWT
Sbjct: 481  LINFIHSFWPSLLKINGFMEEFITPIVKASRKNGEVLSFYSMPEYEAWKESLNGNASGWT 540

Query: 1754 IKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFE 1933
            IKYYKGLGTST+KEGKEYF+Q+RKHKKSF+W+D+QDGE+IELAFSKKKIEARKNWLRQFE
Sbjct: 541  IKYYKGLGTSTSKEGKEYFRQIRKHKKSFIWSDDQDGEAIELAFSKKKIEARKNWLRQFE 600

Query: 1934 AGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKE 2113
             GTYLD + E+I YSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN +KE
Sbjct: 601  PGTYLDQEGEKITYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNFVKE 660

Query: 2114 AKVAQFSGYVSEHSAYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAA 2293
            AKVAQFSGYVSEHSAYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRN+GGKDAA
Sbjct: 661  AKVAQFSGYVSEHSAYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNRGGKDAA 720

Query: 2294 SGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWS 2473
            SGRYIYTCLSPITR+LFPK            GQSIEP+WY+PIIPMVL+NGSEGIGTGWS
Sbjct: 721  SGRYIYTCLSPITRYLFPKDDDLLLDYLDEDGQSIEPSWYVPIIPMVLINGSEGIGTGWS 780

Query: 2474 SYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVD 2653
            SYVPNYNPRDV+ANVRRLLNDEPM+PM+PWYRGF+G+I KSA+KETGVTYTISGIIEEVD
Sbjct: 781  SYVPNYNPRDVIANVRRLLNDEPMQPMDPWYRGFQGIIWKSAEKETGVTYTISGIIEEVD 840

Query: 2654 ITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENM 2833
             +TLRITELPIRSWT +YNEFL+AMM GTDKFKEPFIQDK+AYNDD  VHFE++LSE+NM
Sbjct: 841  SSTLRITELPIRSWTLEYNEFLEAMMNGTDKFKEPFIQDKKAYNDDTTVHFEIMLSEQNM 900

Query: 2834 MAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVX 3013
              AKQEG          IST+NMHLFD +G IKKYDTPEQILEDFFHLRL+FYEKR+K+ 
Sbjct: 901  EVAKQEGLEKKFKLTNTISTTNMHLFDPSGVIKKYDTPEQILEDFFHLRLEFYEKRRKIL 960

Query: 3014 XXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIA 3193
                          VRFIL VV+GEIIVNNR+R DLFLELHQKGFTPFPKKTKGIDAAIA
Sbjct: 961  LDNLEFDLLKLDNKVRFILGVVRGEIIVNNRKRVDLFLELHQKGFTPFPKKTKGIDAAIA 1020

Query: 3194 GATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELR 3373
            GATV+T          VKG VKASDYEYLLS++IG+LTLEKVQ LCADK++L+HELE LR
Sbjct: 1021 GATVETEENEEESPEMVKGAVKASDYEYLLSLAIGTLTLEKVQALCADKERLEHELEMLR 1080

Query: 3374 STSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIRRR-NTGAAVPSKAPKKPRKNNAI 3550
            STS + LWMRDLDALE QLDE DQ+D  AA  ++++R + N GAAV  KAPK  +KNN  
Sbjct: 1081 STSPRALWMRDLDALEAQLDEHDQQDAVAAKTRQEMRAKINKGAAVSRKAPKPLKKNNTT 1140

Query: 3551 KGPTVAANDADADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXXK 3730
            K  ++AA +  A VG+TSTA +AGN                 AKK TVV          K
Sbjct: 1141 K--SIAATETGATVGSTSTATEAGNVTEVAKPKPRGGQKKAPAKKATVVDSDDDEVLELK 1198

Query: 3731 DRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXP 3910
            DRLAAYNLDSSPDQT METE+V +     K  +KRA  RK KST+TIS           P
Sbjct: 1199 DRLAAYNLDSSPDQTSMETEAVGK-----KEANKRAAARKPKSTLTISDDDDDMNAEEMP 1253

Query: 3911 AISEDG-DDGDFQMVEV---XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQK 4078
             I EDG DD DF+M+E                                   +GKSL+SQK
Sbjct: 1254 TIVEDGDDDADFEMMEAAPKGKKGGAGRKPANAKAKGTTTMTTARKRGGGAKGKSLLSQK 1313

Query: 4079 LITDVLKPVVNASPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEM 4258
             ITD+LKPV NASPEKKVRKMRESPFNKKSGSVLGRA G + ESEGS+ S  SVNLE   
Sbjct: 1314 AITDMLKPVENASPEKKVRKMRESPFNKKSGSVLGRAGGSMTESEGSVGSLSSVNLEAGR 1373

Query: 4259 NEVPVARNRPKRENRSKVQYV 4321
            + V V RN PKRENR KV YV
Sbjct: 1374 DVVQVTRNLPKRENRKKVTYV 1394


>ref|XP_010920068.1| PREDICTED: DNA topoisomerase 2 [Elaeis guineensis]
          Length = 1486

 Score = 1950 bits (5052), Expect = 0.0
 Identities = 1011/1450 (69%), Positives = 1127/1450 (77%), Gaps = 11/1450 (0%)
 Frame = +2

Query: 5    GGKKTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIF 184
            G  KTIEE+YQKKTQLEHILLRPDTYIGS+EKHT  LWV+E+GEM +RP++YVPGLYKIF
Sbjct: 27   GPNKTIEEMYQKKTQLEHILLRPDTYIGSVEKHTQTLWVYENGEMVHRPVTYVPGLYKIF 86

Query: 185  DEILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHL 364
            DEILVNAADNKQRDP+MD VKV+ID   N ISVYN+GDG+P+EIHQEEGVYVPEMIFGHL
Sbjct: 87   DEILVNAADNKQRDPSMDSVKVEIDVAGNCISVYNSGDGIPVEIHQEEGVYVPEMIFGHL 146

Query: 365  LTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPS 544
            LTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADG+RQKKYKQVFSENMGKKS+PS
Sbjct: 147  LTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGRRQKKYKQVFSENMGKKSEPS 206

Query: 545  ITKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVP 724
            I KCK GENWTKV+FKPDLAKFNMTHLEDDVVALMKKRVVDLAG LGK VKVELNG R+P
Sbjct: 207  IVKCKEGENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGILGKSVKVELNGQRIP 266

Query: 725  VKTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGG 904
            VK+F DYV+LYL+SA+K+R EPLPRI EK N+RWE+C SLSEGQFQQVSFVNGI T+KGG
Sbjct: 267  VKSFGDYVNLYLQSASKSRPEPLPRISEKVNDRWEICASLSEGQFQQVSFVNGIATVKGG 326

Query: 905  THVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTR 1084
            THVEYVT+QIT                        LWVFVN LIDNPAFDSQTKETLTTR
Sbjct: 327  THVEYVTNQITSHVMSIVNKKNKNANLKAHNVRSHLWVFVNALIDNPAFDSQTKETLTTR 386

Query: 1085 QGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQN-VNIPKLDDAN 1261
            QGSFGSKCELS EFLKKV KSG+V +LLSWADFKQSKELKKTDG+KRQ  V IPKL+DAN
Sbjct: 387  QGSFGSKCELSQEFLKKVAKSGVVNSLLSWADFKQSKELKKTDGTKRQRIVGIPKLEDAN 446

Query: 1262 DAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNA 1441
            DAGG+NS+KCTLILTEGDSAKALA+AG+S VGRN YGVFPL+GKLLNVREAS KQIM NA
Sbjct: 447  DAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNHYGVFPLRGKLLNVREASHKQIMDNA 506

Query: 1442 EIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVK 1621
            EIQ+IKQILGLQ GK+Y+S KGLRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+ 
Sbjct: 507  EIQSIKQILGLQQGKEYESTKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIP 566

Query: 1622 GFMVEFITPIVKASH-KNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEG 1798
             FMVEFITPIVKA+H +N  VL FY+MPEYEAWKESL GNA+GW+IKYYKGLGTST+KEG
Sbjct: 567  SFMVEFITPIVKATHNRNKNVLPFYSMPEYEAWKESLGGNASGWSIKYYKGLGTSTSKEG 626

Query: 1799 KEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYS 1978
            KEYF+ + KHKK F+W D QDG++IELAFSKKKIEARKNWLRQFE GTYLD +E+ IKYS
Sbjct: 627  KEYFQDIVKHKKDFMWVDNQDGDAIELAFSKKKIEARKNWLRQFEPGTYLDQREKLIKYS 686

Query: 1979 DFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSA 2158
            DFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN +KEAKVAQF+GYVSEHSA
Sbjct: 687  DFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFAGYVSEHSA 746

Query: 2159 YHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRF 2338
            YHHGEQSL STI+GMAQDFVGSNNINL QPNGQFGTR++GGKD AS RYIYT LSP+TRF
Sbjct: 747  YHHGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPLTRF 806

Query: 2339 LFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANV 2518
            LFPK            GQ IEP WYMPIIPMVLVNGSEGIGTGWS++VPNYNPRD+VANV
Sbjct: 807  LFPKDDDILLDYLNEDGQLIEPTWYMPIIPMVLVNGSEGIGTGWSTFVPNYNPRDIVANV 866

Query: 2519 RRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWT 2698
            RRLLN+EPM+PM+PWYR FKGLIEKSA KE GVTYTI+G+ EEVD TTL+ITELPIR WT
Sbjct: 867  RRLLNNEPMQPMDPWYRSFKGLIEKSASKEAGVTYTITGLAEEVDSTTLKITELPIRRWT 926

Query: 2699 ADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXX 2878
             DY EFL+++M G DK KEPFI+D R  NDDV VHFE+IL+EE +  A++EG        
Sbjct: 927  QDYKEFLESLMTGNDKIKEPFIKDYREQNDDVNVHFEIILTEEKLNMAREEGLEKKFKLT 986

Query: 2879 XXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXV 3058
              IST+NMHLFDS G IKKYDTPEQILEDFFHLRL+FY KRKK                V
Sbjct: 987  TTISTTNMHLFDSKGVIKKYDTPEQILEDFFHLRLEFYAKRKKALLDNLELDLLKLDNKV 1046

Query: 3059 RFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXX 3238
            RFIL VV+GEIIVNNR+RADLFLEL QKGF PFPKK+KGIDAAIAGATV+          
Sbjct: 1047 RFILGVVRGEIIVNNRKRADLFLELQQKGFAPFPKKSKGIDAAIAGATVEEDGNEESPEV 1106

Query: 3239 TVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDAL 3418
               G  +A+DYEYLLSM+IG+LT EKVQELCA+++KL+ E+EELR +S + LWM+DLDA 
Sbjct: 1107 VNGGGARAADYEYLLSMAIGTLTWEKVQELCAERKKLEDEVEELRKSSPRDLWMKDLDAF 1166

Query: 3419 EKQLDELDQKDVEAANMQEKIRRRNTGAAVPSKAPKKPRKNNAIKGPTVAANDADADVGT 3598
            E +LDE ++KD E    +E   +  TGAA+  + PKKPRKNNA    TV      +DV  
Sbjct: 1167 EMELDEQERKDAEEGIKRETRMKNITGAALSKQGPKKPRKNNANNSSTV------SDV-- 1218

Query: 3599 TSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV---XXXXXXXXXXKDRLAAYNLDSSPD 3769
              T+ DAGN                 AKK  VV             KDRLAAYNLDSSPD
Sbjct: 1219 --TSTDAGNAPEASKPKPRGRAKKAPAKKVAVVESDEDDEEEVLALKDRLAAYNLDSSPD 1276

Query: 3770 -QTFMETESV-AQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDDGDF 3943
             Q+ METE+V +Q+  + K PSKR   RK  ST T             P I ED DD DF
Sbjct: 1277 HQSAMETEAVLSQKEQRKKEPSKRTAARKAPSTFT-EISDGDDAEDDMPTILEDDDDEDF 1335

Query: 3944 QMVEV--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKPVVNA- 4114
            ++VE                                  Q K ++SQKLIT+VLKPV N  
Sbjct: 1336 ELVEAPPKGGKARGKKPANEKAKGGKAGTTTTRKRGTAQSKPVLSQKLITEVLKPVENTG 1395

Query: 4115 -SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEMNEVPVARNRPK 4291
             SPEKKVRKMR SPFNKKSGSVLGR       SE S  SSP      E+NEV  A  RPK
Sbjct: 1396 ISPEKKVRKMRASPFNKKSGSVLGRIGSSPTSSEESGSSSP--GNPAELNEVLAAAARPK 1453

Query: 4292 RENRSKVQYV 4321
            REN  +  Y+
Sbjct: 1454 RENSRRAVYI 1463


>gb|OAY66581.1| DNA topoisomerase 2 [Ananas comosus]
          Length = 1476

 Score = 1949 bits (5050), Expect = 0.0
 Identities = 995/1446 (68%), Positives = 1118/1446 (77%), Gaps = 6/1446 (0%)
 Frame = +2

Query: 2    GGGKKTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKI 181
            GG KKTIEE+YQKKTQLEHILLRPDTYIGS+EKHT  LWV+E+GEM +R ++YVPGLYKI
Sbjct: 24   GGAKKTIEEMYQKKTQLEHILLRPDTYIGSVEKHTQTLWVYENGEMVHRSVTYVPGLYKI 83

Query: 182  FDEILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGH 361
            FDEILVNAADNKQRDP+M+ VKVDIDPE+N ISVYN+GDG+P+EIH EEGVYVPEMIFGH
Sbjct: 84   FDEILVNAADNKQRDPSMNSVKVDIDPEANCISVYNSGDGIPVEIHSEEGVYVPEMIFGH 143

Query: 362  LLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDP 541
            LLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEF+IQTADGK+Q+KYKQVFSENMGKKS+P
Sbjct: 144  LLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFIIQTADGKKQRKYKQVFSENMGKKSEP 203

Query: 542  SITKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRV 721
            SITKCK GENWTKV+FKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGK VKVELNG R+
Sbjct: 204  SITKCKEGENWTKVTFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKSVKVELNGQRL 263

Query: 722  PVKTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKG 901
            PVK+F DYV+LYL++A+K+R EPLPRI+EK N+RWE+CVSLSEGQFQQVSFVNGINTIKG
Sbjct: 264  PVKSFADYVNLYLQAASKSRPEPLPRIVEKVNDRWEICVSLSEGQFQQVSFVNGINTIKG 323

Query: 902  GTHVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTT 1081
            GTHVEYVT+QIT                        LWVFVN LIDNPAFDSQTKETLTT
Sbjct: 324  GTHVEYVTNQITTYVMNVVNKKNKNANLKAHNVRSHLWVFVNALIDNPAFDSQTKETLTT 383

Query: 1082 RQGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDA 1258
            RQGSFGSKCELS EFLKKV KSG+V+ LLSWADFKQSKELKKTDG+KRQ +  IPKL+DA
Sbjct: 384  RQGSFGSKCELSQEFLKKVAKSGVVDNLLSWADFKQSKELKKTDGTKRQRITGIPKLEDA 443

Query: 1259 NDAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQN 1438
            NDAGGKNSDKCTLILTEGDSAKALA+AG+S VGRN YGVFPL+GKLLNVR+A+ KQIM N
Sbjct: 444  NDAGGKNSDKCTLILTEGDSAKALAMAGISVVGRNYYGVFPLRGKLLNVRDANHKQIMDN 503

Query: 1439 AEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKV 1618
            AEIQNIK ILGLQHGKQYDS KGLRYG LMIMTDQDHDGSHIKGLLINF+HSFWPSLLK+
Sbjct: 504  AEIQNIKLILGLQHGKQYDSTKGLRYGHLMIMTDQDHDGSHIKGLLINFVHSFWPSLLKI 563

Query: 1619 KGFMVEFITPIVKASH-KNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKE 1795
              FMVEFITPIVKA+H +N TVLSFY+MPEYEAWKESL G+A GW+IKYYKGLGTST+KE
Sbjct: 564  PSFMVEFITPIVKATHNRNKTVLSFYSMPEYEAWKESLGGSANGWSIKYYKGLGTSTSKE 623

Query: 1796 GKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKY 1975
            GKEYF+ + KHKK FVW DEQDG++I+LAFSKKKIEARKNWLRQFE GTYLD + ++IKY
Sbjct: 624  GKEYFQDIDKHKKDFVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQRMKKIKY 683

Query: 1976 SDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHS 2155
            SDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN +KEAKVAQFSGYVSEHS
Sbjct: 684  SDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHS 743

Query: 2156 AYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITR 2335
            AYHHGEQSL STI+GMAQDFVGSNNINL QPNGQFGTRN+GGKD AS RYIYT LSP+TR
Sbjct: 744  AYHHGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTRNQGGKDHASARYIYTSLSPLTR 803

Query: 2336 FLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVAN 2515
            FLFPK            GQSIEP WY+PIIPMVL+NGSEGIGTGWSS+VPNYNPRD++AN
Sbjct: 804  FLFPKDDDILLDYLNEDGQSIEPTWYIPIIPMVLINGSEGIGTGWSSFVPNYNPRDIIAN 863

Query: 2516 VRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSW 2695
            VRRLLNDEPM+PM+PWYRGFKGLIEKSA KE GVTYTI+GIIEEVD  TLRI ELP+R W
Sbjct: 864  VRRLLNDEPMQPMDPWYRGFKGLIEKSATKEAGVTYTITGIIEEVDNATLRIMELPVRRW 923

Query: 2696 TADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXX 2875
            T DY EFL+A+M G DK KEPFI+D R +NDD  VHFEV L+EEN+  A QEG       
Sbjct: 924  TQDYKEFLEALMTGNDKVKEPFIKDYREHNDDTTVHFEVTLTEENLNIALQEGLEKKFKL 983

Query: 2876 XXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXX 3055
               I T+NMHLFDSNG IKKYDTPEQILEDFFHLRL+FYEKRKKV               
Sbjct: 984  TTTIGTTNMHLFDSNGVIKKYDTPEQILEDFFHLRLEFYEKRKKVLLDNLEMDLLKLDNK 1043

Query: 3056 VRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXX 3235
            VRFIL VV+GEIIVNNR+RA+LF+ELHQKGFTPFPKK+KGID AI GAT +         
Sbjct: 1044 VRFILGVVRGEIIVNNRKRAELFIELHQKGFTPFPKKSKGIDVAIVGATTEEEENEESPE 1103

Query: 3236 XTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDA 3415
               KG V+ASDYEYLLSM+IG+LTLEKVQELC ++ KL+ E+EELR  + + LW++DLDA
Sbjct: 1104 MG-KGGVRASDYEYLLSMAIGTLTLEKVQELCGERDKLESEVEELRKATPRSLWLKDLDA 1162

Query: 3416 LEKQLDELDQKDVEAANMQEKIRRRNTGAAVPSK-APKKPRKNNAIKGPTVAANDADADV 3592
            LE++L+E ++KD EA   +  +R +N GAA  SK   KKPRKN A K  T    D     
Sbjct: 1163 LERELEEQERKDAEADGARRAMRAKNIGAAAASKQGAKKPRKNTANKASTTTLEDT---- 1218

Query: 3593 GTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXXKDRLAAYNLDSSPDQ 3772
                     GN                 AK   V           K+RLAAYNL+SSPD 
Sbjct: 1219 -------SNGNIPEPSKPKPRGPPKKAPAKSKAVESDDEDEVLELKERLAAYNLNSSPDH 1271

Query: 3773 TFMETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDDGDFQMV 3952
            + ME E +  +V   K PSK A  RK  + +T             P I E  DD +F+++
Sbjct: 1272 STMEIEGLVSQVEPEKEPSKGAAARKAPAAIT-HLSDEDGDDDQMPTILEGNDDDEFELL 1330

Query: 3953 EVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKPVVN---ASPE 4123
            E                                Q K  ++QKLIT VLKP      ASP+
Sbjct: 1331 EEAAPKEKKPARGRKPAGDKLKAAVGTRKRGPAQNKPALTQKLITQVLKPSEKAKIASPK 1390

Query: 4124 KKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEMNEVPVARNRPKRENR 4303
            KKVRKMR SPFNKKSG++LG     ++ S  S + S     E    E     NRPKR N 
Sbjct: 1391 KKVRKMRASPFNKKSGTLLGNR---ILSSSASSEDSGGHASEGSSAEAIAPVNRPKRNNI 1447

Query: 4304 SKVQYV 4321
             +  Y+
Sbjct: 1448 QRAVYI 1453


>ref|XP_009399445.1| PREDICTED: DNA topoisomerase 2-like [Musa acuminata subsp.
            malaccensis]
          Length = 1466

 Score = 1917 bits (4967), Expect = 0.0
 Identities = 994/1445 (68%), Positives = 1117/1445 (77%), Gaps = 7/1445 (0%)
 Frame = +2

Query: 8    GKKTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFD 187
            GKKTIEE+YQKKTQLEHILLRPDTYIGS+EKH   LWV+E+GEM +RP++YVPGLYKIFD
Sbjct: 26   GKKTIEEIYQKKTQLEHILLRPDTYIGSVEKHAQTLWVYENGEMVHRPVTYVPGLYKIFD 85

Query: 188  EILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLL 367
            EILVNAADNKQRDP+MD VKV+ID ++N IS+YNNGDGVP+EIHQEEGVYVPE+IFGHLL
Sbjct: 86   EILVNAADNKQRDPSMDAVKVEIDVDANRISIYNNGDGVPVEIHQEEGVYVPELIFGHLL 145

Query: 368  TSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSI 547
            TSSNYDDNVKKTTGGRNGYGAKLTNIFSTEF+I+TADGK+QK+YKQVF++NMGKK+DPSI
Sbjct: 146  TSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFIIETADGKKQKRYKQVFTDNMGKKTDPSI 205

Query: 548  TKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPV 727
            TKCKAGENWTKV+F+PDLAKFNMT+LE+DVVALMKKRVVDLAGTLGK VKVELNG R+PV
Sbjct: 206  TKCKAGENWTKVTFRPDLAKFNMTYLEEDVVALMKKRVVDLAGTLGKSVKVELNGQRLPV 265

Query: 728  KTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGT 907
            KTF DYV+LYL+SA+K+R EPLPRI EKAN+RWE+CVSLSEGQFQQVSFVNGI TIKGGT
Sbjct: 266  KTFADYVNLYLQSASKSRPEPLPRIAEKANDRWEICVSLSEGQFQQVSFVNGIATIKGGT 325

Query: 908  HVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQ 1087
            HVEYVT+QIT                        LWVFVN LIDNPAFDSQTKETLTTRQ
Sbjct: 326  HVEYVTNQITNHIMTIVNKKNKNANLKAHNVRSHLWVFVNVLIDNPAFDSQTKETLTTRQ 385

Query: 1088 GSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDAND 1264
            GSFGSKCELS EFLKKV KSG+V TLL+WADFKQSKELKKTDG+KRQ +  IPKL+DAND
Sbjct: 386  GSFGSKCELSQEFLKKVAKSGVVNTLLTWADFKQSKELKKTDGAKRQRITGIPKLEDAND 445

Query: 1265 AGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAE 1444
            AGGKNSDKCTLILTEGDSAKALA+AG+S VGRN YGVFPL+GKLLNVREA+ KQI+ NAE
Sbjct: 446  AGGKNSDKCTLILTEGDSAKALAMAGISVVGRNYYGVFPLRGKLLNVREANHKQILDNAE 505

Query: 1445 IQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKG 1624
            IQNIKQILGLQHGK+YDS KGLRYG LMIMTDQDHDGSHIKGLLINFIH+FWPSLLKV  
Sbjct: 506  IQNIKQILGLQHGKEYDSAKGLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVPS 565

Query: 1625 FMVEFITPIVKASH-KNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGK 1801
            FMVEFITP++KA++ KN TVLSFY+MPEYEAWKESL GNA GW+IKYYKGLGTS ++EGK
Sbjct: 566  FMVEFITPLLKATNNKNKTVLSFYSMPEYEAWKESLGGNANGWSIKYYKGLGTSKSEEGK 625

Query: 1802 EYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSD 1981
            +YFK + KHKK FVW DEQDG++IELAFSKKKIEARKNWLRQFE   YLD +E+ IKYSD
Sbjct: 626  DYFKAIDKHKKDFVWVDEQDGDAIELAFSKKKIEARKNWLRQFEPENYLDQREKLIKYSD 685

Query: 1982 FVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAY 2161
            F+NKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN +K+AKVAQF GYVSE SAY
Sbjct: 686  FINKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNFVKQAKVAQFVGYVSEKSAY 745

Query: 2162 HHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFL 2341
            HHGEQSL +TI+GMAQDFVGSNNINL QP GQFGTR++GGKD AS RYI+TCLSPITRFL
Sbjct: 746  HHGEQSLATTIIGMAQDFVGSNNINLLQPEGQFGTRHQGGKDHASARYIFTCLSPITRFL 805

Query: 2342 FPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVR 2521
            FPK            GQSIEP WYMPIIPMVL NGSEGIGTGWSSY+PNYNP+D+VANVR
Sbjct: 806  FPKDDDILLDYLNEDGQSIEPTWYMPIIPMVLANGSEGIGTGWSSYIPNYNPKDIVANVR 865

Query: 2522 RLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTA 2701
            RLLN+EPM+PM+PWYRGF G IEKSA KE GVTYTI+G IEEV+ TTLRITELPIR WT 
Sbjct: 866  RLLNNEPMQPMDPWYRGFTGRIEKSATKEAGVTYTITGAIEEVNGTTLRITELPIRRWTQ 925

Query: 2702 DYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXX 2881
            DY EFL++MM G DK KEPFI+D R YNDD  VHFEV L+E+N+  A+QEG         
Sbjct: 926  DYKEFLESMMTGNDKSKEPFIKDYREYNDDKTVHFEVTLTEDNLSIARQEGLEKKFKLTT 985

Query: 2882 XISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVR 3061
             I T+NMHLFD  G IKKYD  EQILE+FFHLR +FYEKRKK                VR
Sbjct: 986  SIGTTNMHLFDPKGVIKKYDNSEQILEEFFHLRYEFYEKRKKALLDNLEFQLLKLDNKVR 1045

Query: 3062 FILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXT 3241
            FIL VV+GEIIVNNR+RADLFLEL QKGF P PKKTKGIDAA      +           
Sbjct: 1046 FILGVVRGEIIVNNRKRADLFLELQQKGFAPMPKKTKGIDAAATEEEEEDEQEEESPEAG 1105

Query: 3242 VKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALE 3421
             +G VKASDYEYL+SM IG+LTLEKVQELCA+K KL+ E++ELR TS + LW+++LDALE
Sbjct: 1106 KRG-VKASDYEYLMSMPIGTLTLEKVQELCAEKDKLEGEVDELRRTSPRSLWLKELDALE 1164

Query: 3422 KQLDELDQKDVEAANMQEKIRRRNTGAAVPSK-APKKPRKNNAIKGPTVAANDADADVGT 3598
            ++LD+L++KD EA    E+IR +N   AVPS+ APKKPRK  + K  T          G 
Sbjct: 1165 EELDKLERKDAEA----EEIRMKNNAGAVPSRQAPKKPRKKASNKSVT----------GP 1210

Query: 3599 TSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXXKDRLAAYNLDSSPDQTF 3778
              T  DAG                   K T +           KDRLAAYNLDSSPDQT 
Sbjct: 1211 EKTVTDAGQ-----KKTNGGSKRAPVKKNTVIESDEDDDIDDLKDRLAAYNLDSSPDQTV 1265

Query: 3779 METESVA--QEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDDGDFQMV 3952
            MET+SV   Q+  + K  S+ A  RK   T+ +S           P I ED  D DF +V
Sbjct: 1266 METDSVVVEQQGGQKKQASRTAAARKATHTV-LSDNEDDEAQNYMPTIEED-KDKDFNLV 1323

Query: 3953 EVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKPVVNA--SPEK 4126
            E                                  K ++SQKLIT+VLKP  N   SPEK
Sbjct: 1324 E---PKGRKVRGRKPANEKAKPATTTRKRGPAQSSKPVLSQKLITEVLKPAENGGNSPEK 1380

Query: 4127 KVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEMNEVPVARNRPKRENRS 4306
            K+RKMR+SPFNK+SGSVLGR       SE S   SPS   E   N V  AR RPKREN +
Sbjct: 1381 KMRKMRDSPFNKRSGSVLGRPTSSPSGSEDSNGLSPSGPAET-TNVVAAARTRPKRENMT 1439

Query: 4307 KVQYV 4321
            K  YV
Sbjct: 1440 KAVYV 1444


>ref|XP_010241213.1| PREDICTED: DNA topoisomerase 2-like isoform X1 [Nelumbo nucifera]
          Length = 1504

 Score = 1909 bits (4944), Expect = 0.0
 Identities = 987/1470 (67%), Positives = 1111/1470 (75%), Gaps = 31/1470 (2%)
 Frame = +2

Query: 5    GGKKTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIF 184
            G  KTIEE YQKK+QLEHILLRPDTY+GSIEKHT  LWV++ GEM +RP++YVPGLYKIF
Sbjct: 25   GSGKTIEETYQKKSQLEHILLRPDTYVGSIEKHTQTLWVYDGGEMVHRPVTYVPGLYKIF 84

Query: 185  DEILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHL 364
            DEILVNAADNKQRDP+MD VKV ID E N ISVYNNGDGVP+EIHQEEGVYVPE+IFGHL
Sbjct: 85   DEILVNAADNKQRDPSMDSVKVVIDAEQNCISVYNNGDGVPVEIHQEEGVYVPELIFGHL 144

Query: 365  LTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPS 544
            LTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+I+TADGKRQKKYKQVFS NMGKKS+P+
Sbjct: 145  LTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFIIETADGKRQKKYKQVFSNNMGKKSEPA 204

Query: 545  ITKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVP 724
            ITKCK  ENWTKV+FKPDLAKFN+THLEDDVVALMKKRV+DLAG LGK VKVELNG RVP
Sbjct: 205  ITKCKGSENWTKVTFKPDLAKFNLTHLEDDVVALMKKRVIDLAGCLGKTVKVELNGQRVP 264

Query: 725  VKTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGG 904
            VK+F DYV+LYL+SA+K+R EPLPRI EK + RWEVCVSLSEGQFQQVSFVNGI TIKGG
Sbjct: 265  VKSFLDYVNLYLQSASKSRPEPLPRITEKVSERWEVCVSLSEGQFQQVSFVNGIATIKGG 324

Query: 905  THVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTR 1084
            THV+YVT+QIT                        LWVFVN+LIDNPAFDSQTKETLTTR
Sbjct: 325  THVDYVTNQITNHVMTIVNKKNKNANLKAHTVKNHLWVFVNSLIDNPAFDSQTKETLTTR 384

Query: 1085 QGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDAN 1261
            Q SFGSKCELS EFLKKV KSG+VE LLSWADFKQSK+LKKTDG+KRQ +  I KL+DAN
Sbjct: 385  QSSFGSKCELSQEFLKKVAKSGVVENLLSWADFKQSKDLKKTDGAKRQRITGITKLEDAN 444

Query: 1262 DAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNA 1441
            DAGG+NS+KCTLILTEGDSAKALA+AG+S VGRN YGVFPL+GKLLNVREA+ KQIM NA
Sbjct: 445  DAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNNYGVFPLRGKLLNVREATHKQIMDNA 504

Query: 1442 EIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVK 1621
            EIQNIKQILGLQHGK+YDSVK LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+ 
Sbjct: 505  EIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIP 564

Query: 1622 GFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGK 1801
             F+VEFITPIVKA+HKNG VLSFY+MPEYE+WK  L GNA+GW+IKYYKGLGTST+KEGK
Sbjct: 565  SFLVEFITPIVKATHKNGKVLSFYSMPEYESWKX-LGGNASGWSIKYYKGLGTSTSKEGK 623

Query: 1802 EYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSD 1981
            EYFK L KHKK F+W D++DG++IELAFSKKKIEARKNWLRQFE GT LD KE+ IKYSD
Sbjct: 624  EYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLIKYSD 683

Query: 1982 FVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAY 2161
            FVNKELILFS ADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAY
Sbjct: 684  FVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAY 743

Query: 2162 HHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFL 2341
            HHGEQSL+STI+GMAQD+VGSNNINLFQPNGQFGTR++GGKD AS RYIYT LSPITRFL
Sbjct: 744  HHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFL 803

Query: 2342 FPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVR 2521
            FPK            GQSIEP WYMPIIP VLVNGSEGIGTGWSSY+PNYNPRD+VAN++
Sbjct: 804  FPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIK 863

Query: 2522 RLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTA 2701
            RLLN EPM PM+PWY+GFKGLIEK+A KE G +YT+SGIIEE++ TTLRITELPIR WT 
Sbjct: 864  RLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIRRWTQ 923

Query: 2702 DYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXX 2881
            DY EFL+++M G DK KEPFI+D + +NDD  VHFE+ILSEEN+M AKQEG         
Sbjct: 924  DYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTT 983

Query: 2882 XISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVR 3061
             ISTSNMHLFD  GTIKKYD PEQILE+FFHLRL+FYEKRKK                VR
Sbjct: 984  TISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVR 1043

Query: 3062 FILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXT 3241
            FIL VVKGEIIV+NR+R DLFLEL QKGFTPFPKKTK ++AA+AGA  D           
Sbjct: 1044 FILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVV 1103

Query: 3242 VKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALE 3421
                V+ASDYEYLLSM+IG+LTLEKVQELC+D+ KL+HE+EELR  +   LWM DLDALE
Sbjct: 1104 SSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALE 1163

Query: 3422 KQLDELDQKDVEAANMQEKIRRR---NTGAAVPSKAPKKPRKNNAIKGPTVAANDADADV 3592
            K+LDE D+ D +A   +++++ R     G     +APK PRK NA K  T          
Sbjct: 1164 KELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKNPRKTNAKKPSTSETVTESVAA 1223

Query: 3593 GTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTV----VXXXXXXXXXXKDRLAAYNLDS 3760
             +  +AM+                   A K+  +               K+RLAAYNLDS
Sbjct: 1224 SSVGSAMETVPEVVKPKGRGGRPKKAPAKKQDNMRLVDSDEDDVDVIELKERLAAYNLDS 1283

Query: 3761 SPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDDGD 3940
            SP+Q+ +    VA+   K K PSKRA  +K  S+ T               IS+D D  D
Sbjct: 1284 SPEQSAVMETEVAKVPAKKKEPSKRAAAQKQPSSYT--------------EISDDDDGMD 1329

Query: 3941 FQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGK---------------SLVSQ 4075
             Q +                                  GK               S++ Q
Sbjct: 1330 VQTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAANGKAAASTKKRGAANKQTSVLGQ 1389

Query: 4076 KLITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARG------PVVESEGSIDSS 4231
            K ITD+LKP  NA  SPEKKVRKMR SPFNKKSGSVLGR  G      P+   E    +S
Sbjct: 1390 KKITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVGGMVGDISPMGSEEQQTGTS 1449

Query: 4232 PSVNLEVEMNEVPVARNRPKRENRSKVQYV 4321
             +     E++EV  AR RP+R NR K +YV
Sbjct: 1450 SASTDSAELSEVVPARPRPQRVNRGKAKYV 1479


>ref|XP_010241214.1| PREDICTED: DNA topoisomerase 2-like isoform X2 [Nelumbo nucifera]
          Length = 1503

 Score = 1908 bits (4942), Expect = 0.0
 Identities = 987/1469 (67%), Positives = 1110/1469 (75%), Gaps = 30/1469 (2%)
 Frame = +2

Query: 5    GGKKTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIF 184
            G  KTIEE YQKK+QLEHILLRPDTY+GSIEKHT  LWV++ GEM +RP++YVPGLYKIF
Sbjct: 25   GSGKTIEETYQKKSQLEHILLRPDTYVGSIEKHTQTLWVYDGGEMVHRPVTYVPGLYKIF 84

Query: 185  DEILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHL 364
            DEILVNAADNKQRDP+MD VKV ID E N ISVYNNGDGVP+EIHQEEGVYVPE+IFGHL
Sbjct: 85   DEILVNAADNKQRDPSMDSVKVVIDAEQNCISVYNNGDGVPVEIHQEEGVYVPELIFGHL 144

Query: 365  LTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPS 544
            LTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+I+TADGKRQKKYKQVFS NMGKKS+P+
Sbjct: 145  LTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFIIETADGKRQKKYKQVFSNNMGKKSEPA 204

Query: 545  ITKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVP 724
            ITKCK  ENWTKV+FKPDLAKFN+THLEDDVVALMKKRV+DLAG LGK VKVELNG RVP
Sbjct: 205  ITKCKGSENWTKVTFKPDLAKFNLTHLEDDVVALMKKRVIDLAGCLGKTVKVELNGQRVP 264

Query: 725  VKTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGG 904
            VK+F DYV+LYL+SA+K+R EPLPRI EK + RWEVCVSLSEGQFQQVSFVNGI TIKGG
Sbjct: 265  VKSFLDYVNLYLQSASKSRPEPLPRITEKVSERWEVCVSLSEGQFQQVSFVNGIATIKGG 324

Query: 905  THVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTR 1084
            THV+YVT+QIT                        LWVFVN+LIDNPAFDSQTKETLTTR
Sbjct: 325  THVDYVTNQITNHVMTIVNKKNKNANLKAHTVKNHLWVFVNSLIDNPAFDSQTKETLTTR 384

Query: 1085 QGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDAN 1261
            Q SFGSKCELS EFLKKV KSG+VE LLSWADFKQSK+LKKTDG+KRQ +  I KL+DAN
Sbjct: 385  QSSFGSKCELSQEFLKKVAKSGVVENLLSWADFKQSKDLKKTDGAKRQRITGITKLEDAN 444

Query: 1262 DAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNA 1441
            DAGG+NS+KCTLILTEGDSAKALA+AG+S VGRN YGVFPL+GKLLNVREA+ KQIM NA
Sbjct: 445  DAGGRNSEKCTLILTEGDSAKALAMAGISVVGRNNYGVFPLRGKLLNVREATHKQIMDNA 504

Query: 1442 EIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVK 1621
            EIQNIKQILGLQHGK+YDSVK LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+ 
Sbjct: 505  EIQNIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIP 564

Query: 1622 GFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGK 1801
             F+VEFITPIVKA+HKNG VLSFY+MPEYE+WK  L GNA+GW+IKYYKGLGTST+KEGK
Sbjct: 565  SFLVEFITPIVKATHKNGKVLSFYSMPEYESWKX-LGGNASGWSIKYYKGLGTSTSKEGK 623

Query: 1802 EYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSD 1981
            EYFK L KHKK F+W D++DG++IELAFSKKKIEARKNWLRQFE GT LD KE+ IKYSD
Sbjct: 624  EYFKDLHKHKKDFLWVDDRDGDAIELAFSKKKIEARKNWLRQFEPGTCLDQKEKLIKYSD 683

Query: 1982 FVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAY 2161
            FVNKELILFS ADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAY
Sbjct: 684  FVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAY 743

Query: 2162 HHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFL 2341
            HHGEQSL+STI+GMAQD+VGSNNINLFQPNGQFGTR++GGKD AS RYIYT LSPITRFL
Sbjct: 744  HHGEQSLMSTIIGMAQDYVGSNNINLFQPNGQFGTRHQGGKDHASARYIYTRLSPITRFL 803

Query: 2342 FPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVR 2521
            FPK            GQSIEP WYMPIIP VLVNGSEGIGTGWSSY+PNYNPRD+VAN++
Sbjct: 804  FPKGDDILLDYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIK 863

Query: 2522 RLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTA 2701
            RLLN EPM PM+PWY+GFKGLIEK+A KE G +YT+SGIIEE++ TTLRITELPIR WT 
Sbjct: 864  RLLNGEPMEPMDPWYKGFKGLIEKTATKEAGSSYTVSGIIEEINETTLRITELPIRRWTQ 923

Query: 2702 DYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXX 2881
            DY EFL+++M G DK KEPFI+D + +NDD  VHFE+ILSEEN+M AKQEG         
Sbjct: 924  DYKEFLESIMTGNDKIKEPFIKDYKEHNDDTTVHFEIILSEENLMMAKQEGLMKKFKLTT 983

Query: 2882 XISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVR 3061
             ISTSNMHLFD  GTIKKYD PEQILE+FFHLRL+FYEKRKK                VR
Sbjct: 984  TISTSNMHLFDPKGTIKKYDNPEQILEEFFHLRLEFYEKRKKTQLDNLELDLLKLDNKVR 1043

Query: 3062 FILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXT 3241
            FIL VVKGEIIV+NR+R DLFLEL QKGFTPFPKKTK ++AA+AGA  D           
Sbjct: 1044 FILGVVKGEIIVSNRKRVDLFLELQQKGFTPFPKKTKALEAAVAGANEDGEENEENSEVV 1103

Query: 3242 VKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALE 3421
                V+ASDYEYLLSM+IG+LTLEKVQELC+D+ KL+HE+EELR  +   LWM DLDALE
Sbjct: 1104 SSRGVRASDYEYLLSMAIGTLTLEKVQELCSDRDKLNHEVEELRKATPNSLWMNDLDALE 1163

Query: 3422 KQLDELDQKDVEAANMQEKIRRR---NTGAAVPSKAPKKPRKNNAIKGPTVAANDADADV 3592
            K+LDE D+ D +A   +++++ R     G     +APK PRK NA K  T          
Sbjct: 1164 KELDEQDKNDAQAEEARKELKNRVMSEAGMKASRQAPKNPRKTNAKKPSTSETVTESVAA 1223

Query: 3593 GTTSTAMDAGNXXXXXXXXXXXXXXXDAAK---KTTVVXXXXXXXXXXKDRLAAYNLDSS 3763
             +  +AM+                   A K   +              K+RLAAYNLDSS
Sbjct: 1224 SSVGSAMETVPEVVKPKGRGGRPKKAPAKKDNMRLVDSDEDDVDVIELKERLAAYNLDSS 1283

Query: 3764 PDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDDGDF 3943
            P+Q+ +    VA+   K K PSKRA  +K  S+ T               IS+D D  D 
Sbjct: 1284 PEQSAVMETEVAKVPAKKKEPSKRAAAQKQPSSYT--------------EISDDDDGMDV 1329

Query: 3944 QMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGK---------------SLVSQK 4078
            Q +                                  GK               S++ QK
Sbjct: 1330 QTIREESIGEIVSDEDFEPEVEEAPKGGRGGRKPAANGKAAASTKKRGAANKQTSVLGQK 1389

Query: 4079 LITDVLKPVVNA--SPEKKVRKMRESPFNKKSGSVLGRARG------PVVESEGSIDSSP 4234
             ITD+LKP  NA  SPEKKVRKMR SPFNKKSGSVLGR  G      P+   E    +S 
Sbjct: 1390 KITDLLKPAENAGVSPEKKVRKMRASPFNKKSGSVLGRVGGMVGDISPMGSEEQQTGTSS 1449

Query: 4235 SVNLEVEMNEVPVARNRPKRENRSKVQYV 4321
            +     E++EV  AR RP+R NR K +YV
Sbjct: 1450 ASTDSAELSEVVPARPRPQRVNRGKAKYV 1478


>ref|XP_009402954.1| PREDICTED: DNA topoisomerase 2-like [Musa acuminata subsp.
            malaccensis]
          Length = 1473

 Score = 1906 bits (4937), Expect = 0.0
 Identities = 987/1454 (67%), Positives = 1121/1454 (77%), Gaps = 15/1454 (1%)
 Frame = +2

Query: 5    GGKKTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIF 184
            GGKKTIE++YQKKTQLEHILLRPDTYIGS+EKHT  LWV+E+GEM +RP++YVPGLYKIF
Sbjct: 31   GGKKTIEQIYQKKTQLEHILLRPDTYIGSVEKHTQPLWVYENGEMVHRPVTYVPGLYKIF 90

Query: 185  DEILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHL 364
            DEILVNAADNKQRDP+MD VKV+ID ++N IS+YNNGDGVP+EIHQEE VYVPE+IFGHL
Sbjct: 91   DEILVNAADNKQRDPSMDTVKVEIDVDANRISIYNNGDGVPVEIHQEERVYVPELIFGHL 150

Query: 365  LTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPS 544
            LTSSNYDDNVKKTTGGRNGYGAKLTNIFS EF+I+TADG+RQKKYKQVFS+NMGK+SDPS
Sbjct: 151  LTSSNYDDNVKKTTGGRNGYGAKLTNIFSAEFIIETADGRRQKKYKQVFSDNMGKRSDPS 210

Query: 545  ITKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVP 724
            ITKCK GENWTKV+F+PDLAKFNMT LE+DVVALMKKRVVDLAGTLGK VKVELNG R+P
Sbjct: 211  ITKCKEGENWTKVTFRPDLAKFNMTRLEEDVVALMKKRVVDLAGTLGKSVKVELNGQRIP 270

Query: 725  VKTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGG 904
            VKTF+DYV+LYL+SA+K+R EPLPRI EK N RWE+CVSLSEGQFQQVSFVNGI+TIKGG
Sbjct: 271  VKTFSDYVNLYLQSASKSRTEPLPRIAEKVNERWEICVSLSEGQFQQVSFVNGISTIKGG 330

Query: 905  THVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTR 1084
            THVE VT+QIT                        LWVFVN LI+NPAFDSQTKETLTTR
Sbjct: 331  THVECVTNQITNHIMTVVNKKNKNANLKAHNVRSHLWVFVNALINNPAFDSQTKETLTTR 390

Query: 1085 QGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDAN 1261
            QGSFGSKCELS EFLKKV KSG+V TLL+WADFKQSKELKKTDG+KRQ +  IPKL+DAN
Sbjct: 391  QGSFGSKCELSQEFLKKVAKSGVVNTLLTWADFKQSKELKKTDGAKRQRITGIPKLEDAN 450

Query: 1262 DAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNA 1441
            DAGG+NSDKCTL+LTEGDSAKALA+AG+S VGRN YGVFPL+GKLLNVREA+ KQIM NA
Sbjct: 451  DAGGRNSDKCTLVLTEGDSAKALAMAGISVVGRNYYGVFPLRGKLLNVREANHKQIMDNA 510

Query: 1442 EIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVK 1621
            EIQN+KQILGLQHGK+YDS KGLRYG LMIMTDQDHDGSHIKGLLINFIH+FWPSLLKV 
Sbjct: 511  EIQNVKQILGLQHGKEYDSTKGLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKVP 570

Query: 1622 GFMVEFITPIVKASH-KNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEG 1798
             FMVEFITP++KA++ KN TVLSFY+MPEYEAWKESL GN++GW+IKYYKGLGTS ++EG
Sbjct: 571  SFMVEFITPLLKATNNKNKTVLSFYSMPEYEAWKESLGGNSSGWSIKYYKGLGTSKSEEG 630

Query: 1799 KEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYS 1978
            KEYFK + KHKK FVWADEQDG +IELAFSKKKIEARKNWLRQFE   YLD K++ IKYS
Sbjct: 631  KEYFKDIDKHKKEFVWADEQDGNAIELAFSKKKIEARKNWLRQFEPDNYLDQKQKLIKYS 690

Query: 1979 DFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSA 2158
            DF+NKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRN +K+AKVAQF GYVSE SA
Sbjct: 691  DFINKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNFVKQAKVAQFVGYVSEKSA 750

Query: 2159 YHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRF 2338
            YHHGEQSL +TI+GMAQDFVGSNNINL  P GQFGTR++GGKD AS RYI+TC+SP+TRF
Sbjct: 751  YHHGEQSLSTTIIGMAQDFVGSNNINLLLPEGQFGTRHQGGKDHASARYIFTCMSPVTRF 810

Query: 2339 LFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANV 2518
            LF K            GQSIEP WYMP+IP VLVNGSEGIGTGWSSYVPNYNP+D+VAN+
Sbjct: 811  LFSKDDDILLDYLNEDGQSIEPTWYMPVIPTVLVNGSEGIGTGWSSYVPNYNPKDIVANI 870

Query: 2519 RRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWT 2698
            RRLLNDEPM+PM+PWYRGFKG IEKSA KE GVTYTI+G+IEEVD TTLRITELP+R WT
Sbjct: 871  RRLLNDEPMQPMDPWYRGFKGRIEKSATKEAGVTYTIAGVIEEVDNTTLRITELPVRRWT 930

Query: 2699 ADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXX 2878
             DY EFL++MM G DK KEPFI+D R YNDD  VHFEV L+EENM  A+QEG        
Sbjct: 931  QDYKEFLESMMTGNDKIKEPFIKDYREYNDDKTVHFEVTLTEENMNIARQEGLEKKFKLT 990

Query: 2879 XXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXV 3058
              I T+NMHLFDS G IKKYD PEQILE+FFH+R +FYEKRKK                 
Sbjct: 991  TTIGTTNMHLFDSKGVIKKYDNPEQILEEFFHMRYEFYEKRKKALLDNLELDLLKLDNKA 1050

Query: 3059 RFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXX 3238
            RFIL VV+GEIIV+NR+RADLFLEL QKGFTP PKK KGIDA +AGA  +          
Sbjct: 1051 RFILGVVRGEIIVSNRKRADLFLELQQKGFTPMPKKKKGIDAVVAGAVEEEEDQEEESPE 1110

Query: 3239 TVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDAL 3418
              KG VKASDYEYL+ M IGSLTLEKVQELCADK +L+ E++ELR TS+K LW+++LDAL
Sbjct: 1111 VGKGGVKASDYEYLMCMPIGSLTLEKVQELCADKDRLEGEVDELRRTSAKSLWLKELDAL 1170

Query: 3419 EKQLDELDQKDVEAANMQEKIRRRNTGAAVPSK-APKKPRKNNAIKGPTVAANDADADVG 3595
            E++LD+L++KD E   +++++R + T    PS+  PKKPRKN        AAN++   VG
Sbjct: 1171 EEELDKLERKDAEDEGVRKEMRMKTTAGLAPSRPGPKKPRKN--------AANNSSV-VG 1221

Query: 3596 TTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV--XXXXXXXXXXKDRLAAYNLDSSPD 3769
            + +TA DAG                  AK+  VV            KDRLAAYNLDSSPD
Sbjct: 1222 SEATATDAGQKKPRGATKRA------PAKQRVVVESGDEDDDILALKDRLAAYNLDSSPD 1275

Query: 3770 -QTFMETES--VAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDDGD 3940
                MET    V Q   K +A    A  RK  S + +S           PAI ED D+ D
Sbjct: 1276 HHPAMETTDAVVGQGEDKKQADRNSAATRKATS-IDLSDDEDNEAGNHMPAIDEDNDE-D 1333

Query: 3941 FQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKPVVNA-- 4114
            F +VE                                    + SQK IT+VLKP  NA  
Sbjct: 1334 FSVVEAPKGGKGRGKKPAKEKATTTATRKRGL------ALPVSSQKRITEVLKPAENATT 1387

Query: 4115 --SPEKKVRKMRESPFNKKSGSVLGRARGPVVESE---GSIDSSPSVNLEVEMNEVPVAR 4279
              SP+KKVRKMR SPFN KSGSVLGR +G    SE   GS +  PS      +NEV  AR
Sbjct: 1388 RISPQKKVRKMRASPFNNKSGSVLGRLKGSPSGSEDSGGSSNGGPS-----PINEVAAAR 1442

Query: 4280 NRPKRENRSKVQYV 4321
             RP+R N ++  YV
Sbjct: 1443 TRPRRANSTRAVYV 1456


>ref|XP_020693654.1| DNA topoisomerase 2 [Dendrobium catenatum]
 gb|PKU72193.1| DNA topoisomerase 2 [Dendrobium catenatum]
          Length = 1466

 Score = 1901 bits (4924), Expect = 0.0
 Identities = 977/1443 (67%), Positives = 1120/1443 (77%), Gaps = 5/1443 (0%)
 Frame = +2

Query: 8    GKKTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFD 187
            GKKTIEE+YQKKTQLEHILLRPDTYIGS+EKHT  LWV+E+ EM +RP++YVPGLYKIFD
Sbjct: 28   GKKTIEEMYQKKTQLEHILLRPDTYIGSVEKHTQTLWVYENEEMVHRPVTYVPGLYKIFD 87

Query: 188  EILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLL 367
            EILVNAADNKQRDP+MD +KVDID E+  IS+YNNGDGVP+EIHQEEGVYVPEMIFGHLL
Sbjct: 88   EILVNAADNKQRDPSMDSLKVDIDAEAVCISIYNNGDGVPVEIHQEEGVYVPEMIFGHLL 147

Query: 368  TSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSI 547
            TSSNYDDNVKKTTGGRNGYGAKLTNIFSTEF+IQTADGKRQKKYKQVF+ NMG KS PSI
Sbjct: 148  TSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFIIQTADGKRQKKYKQVFTGNMGTKSQPSI 207

Query: 548  TKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPV 727
            TKCK GENWTKV+FKPDL KFNM HLE+DVVALMKKRVVDLAGTLGK VKVELNG R+PV
Sbjct: 208  TKCKEGENWTKVTFKPDLLKFNMDHLEEDVVALMKKRVVDLAGTLGKTVKVELNGKRLPV 267

Query: 728  KTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGT 907
            KTF DYV+LYL+SA+K+R EPLPRI EK N+RWE+CVSL++GQFQQVSFVN INTIKGGT
Sbjct: 268  KTFADYVNLYLQSASKSRPEPLPRIAEKVNDRWEICVSLTDGQFQQVSFVNSINTIKGGT 327

Query: 908  HVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQ 1087
            HVEYVTSQI                         LWVFVN LIDNPAFDSQTKETLTTRQ
Sbjct: 328  HVEYVTSQIASHVMSIVNKKNKNANLRPHNVKNHLWVFVNCLIDNPAFDSQTKETLTTRQ 387

Query: 1088 GSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDAND 1264
            GSFGSKC+LS EFLKKV KSGIVE+LLSWADFKQ+KELKKTDG+KRQ ++ I KLDDAND
Sbjct: 388  GSFGSKCDLSQEFLKKVAKSGIVESLLSWADFKQNKELKKTDGTKRQKISGIVKLDDAND 447

Query: 1265 AGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAE 1444
            AGGKNS+KCTLILTEGDSAKALA+AG+S VGRN YGVFPL+GKLLNVREAS KQIM+NAE
Sbjct: 448  AGGKNSEKCTLILTEGDSAKALAMAGISVVGRNNYGVFPLRGKLLNVREASHKQIMENAE 507

Query: 1445 IQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKG 1624
            IQNIKQILGLQ GK+Y+SVKGLRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+  
Sbjct: 508  IQNIKQILGLQQGKEYESVKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPS 567

Query: 1625 FMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGKE 1804
            F+VEFITPIVKA+++ G VLSFYTMPEYE+WKESL GNA+GW+IKYYKGLGTST+KEGKE
Sbjct: 568  FLVEFITPIVKATYRTGKVLSFYTMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKE 627

Query: 1805 YFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSDF 1984
            YF+ L+KHKK FVW DEQDGE+IELAFSKKKIEARKNWLRQFE GTYLD  E+ I YSDF
Sbjct: 628  YFQDLQKHKKDFVWFDEQDGEAIELAFSKKKIEARKNWLRQFEPGTYLDQNEKLISYSDF 687

Query: 1985 VNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYH 2164
            VNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN +KEAK++QFSGYVSEHSAYH
Sbjct: 688  VNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKISQFSGYVSEHSAYH 747

Query: 2165 HGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFLF 2344
            HGEQSL STI+GMAQDFVGSNNINL QPNGQFGTR++GGKD AS RYIYT LSP+TRFLF
Sbjct: 748  HGEQSLASTIIGMAQDFVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTKLSPMTRFLF 807

Query: 2345 PKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVRR 2524
            PK            GQSIEPAWY+PIIPMVLVNGSEGIGTGWSSY+PNYNPRD+V N+RR
Sbjct: 808  PKEDDLILDYMSEDGQSIEPAWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVKNLRR 867

Query: 2525 LLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTAD 2704
            LLNDEPM PM+PWYRGFKGLIEK+A KE   TYT++GIIEE D  TL ITELP+R WT D
Sbjct: 868  LLNDEPMLPMDPWYRGFKGLIEKTAVKEACATYTVTGIIEESDSNTLTITELPVRRWTQD 927

Query: 2705 YNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXXX 2884
            Y EFL++++ GTDK KEPFI+D R YNDD  VHFEV LS++N++ AKQEG          
Sbjct: 928  YKEFLESLVTGTDKVKEPFIKDYREYNDDTTVHFEVTLSDQNLIMAKQEGLEKKFKLSTT 987

Query: 2885 ISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVRF 3064
            ISTSNMHLFD  G IKKYDTPEQILE+FFHLR+ +YEKRKK                VRF
Sbjct: 988  ISTSNMHLFDHKGVIKKYDTPEQILEEFFHLRITYYEKRKKALLDNLELDLLKLDNKVRF 1047

Query: 3065 ILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXTV 3244
            IL VVKG+IIVNNR+RA+LFLEL +KGFTPFPKKTKG+D AIAGAT +T          V
Sbjct: 1048 ILGVVKGQIIVNNRKRAELFLELQEKGFTPFPKKTKGVDVAIAGATPET-EESEETTEVV 1106

Query: 3245 KGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALEK 3424
            KG VK SDY+YLLS++IG+LT EKVQELC++K+K +++++ELR +S   LW++DLDAL+K
Sbjct: 1107 KGGVKPSDYDYLLSLAIGTLTWEKVQELCSEKEKFENDVKELRGSSPSSLWIKDLDALDK 1166

Query: 3425 QLDELDQKDVEAANMQEKIRRR--NTGAAVPSKAPKKPRKNNAIKGPTVAANDADADVGT 3598
            +LD L+++D EA   ++KI+ +  N GAA   +APKKPRKNN    P+ A         T
Sbjct: 1167 ELDNLERQDAEAEVTRKKIKAKAGNGGAAAAKQAPKKPRKNNT--KPSAA---------T 1215

Query: 3599 TSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXXKDRLAAYNLDSSPDQTF 3778
               A+D+                   ++  +V           K+RL AYNLDSSP++  
Sbjct: 1216 EPIAIDSETVQEVTKNKPKRLQNKSKSQPVSVESDEDEDLVALKERLEAYNLDSSPERLA 1275

Query: 3779 METESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDDGDFQMVEV 3958
            METE++ +     + P KRA     +  MT+                ED DD DF+  +V
Sbjct: 1276 METETMPEAAAAKEGPKKRAAA--ARKAMTV-------------VSDEDTDDEDFENSKV 1320

Query: 3959 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKPVVNA--SPEKKV 4132
                                           Q K L++QKLI+++L P  NA  SPEKKV
Sbjct: 1321 -PKGKKGAGGGRKPANATKAKATITTKKREGQIKPLLAQKLISELLPPATNAVDSPEKKV 1379

Query: 4133 RKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEMNEVPVARNRPKRENRSKV 4312
            RK+R SPFNKKSGS L ++    +    S +SS   + E +  E  VA+ RPKRENR++ 
Sbjct: 1380 RKIRPSPFNKKSGSFLDKSG---INGSSSENSSLGTSDEAQ-REDSVAKARPKRENRTRA 1435

Query: 4313 QYV 4321
             YV
Sbjct: 1436 VYV 1438


>ref|XP_020577441.1| DNA topoisomerase 2 [Phalaenopsis equestris]
          Length = 1468

 Score = 1882 bits (4876), Expect = 0.0
 Identities = 977/1445 (67%), Positives = 1106/1445 (76%), Gaps = 7/1445 (0%)
 Frame = +2

Query: 8    GKKTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFD 187
            GKKTIEE+YQKKTQLEHILLRPDTYIGS+EKHT  LWV+E+ EM +RP++YVPGLYKIFD
Sbjct: 30   GKKTIEEIYQKKTQLEHILLRPDTYIGSVEKHTQALWVYENEEMVHRPVTYVPGLYKIFD 89

Query: 188  EILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLL 367
            EILVNAADNKQRDP+MD +KVDID E+N IS+YNNGDGVP+EIHQEEGVYVPEMIFGHLL
Sbjct: 90   EILVNAADNKQRDPSMDSLKVDIDAEANCISIYNNGDGVPVEIHQEEGVYVPEMIFGHLL 149

Query: 368  TSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSI 547
            TSSNYDDNVKKTTGGRNGYGAKLTNIFSTEF+IQTADGKRQKKYKQVFS NMG K+ PSI
Sbjct: 150  TSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFIIQTADGKRQKKYKQVFSGNMGTKTQPSI 209

Query: 548  TKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPV 727
            TKCK GENWTKV+FKPDL KFNM HLE+DVVALMKKRVVDLAGTLGK VKV+LNG RVPV
Sbjct: 210  TKCKEGENWTKVTFKPDLLKFNMDHLEEDVVALMKKRVVDLAGTLGKTVKVDLNGKRVPV 269

Query: 728  KTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGT 907
            KTF DYV+LYL++A+K+R EPLPRI+EK N+RWE+C+SLS+GQFQQVSFVN INTIKGGT
Sbjct: 270  KTFGDYVNLYLQTASKSRSEPLPRIVEKVNDRWEICISLSDGQFQQVSFVNSINTIKGGT 329

Query: 908  HVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQ 1087
            HVEYVTSQI                         LWVFVN LIDNPAFDSQTKETLTTRQ
Sbjct: 330  HVEYVTSQIASHVMSIVNKKNKNANLKPHNVKSHLWVFVNCLIDNPAFDSQTKETLTTRQ 389

Query: 1088 GSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDAND 1264
            GSFGSKC+LS +FLKKV KSGIVE LLSWADFKQ KELKKTDG+KRQ +  I KLDDAND
Sbjct: 390  GSFGSKCDLSQDFLKKVAKSGIVENLLSWADFKQHKELKKTDGAKRQKITGISKLDDAND 449

Query: 1265 AGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAE 1444
            AGGK+SDKCTLILTEGDSAKALA+ G++ VGR+ YGVFPL+GKLLNVREAS KQIM+NAE
Sbjct: 450  AGGKHSDKCTLILTEGDSAKALAMGGIAVVGRDYYGVFPLRGKLLNVREASHKQIMENAE 509

Query: 1445 IQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKG 1624
            IQNIKQILGLQ GKQYDSVKGLRYG LMIMTDQDHDGSHIKGLLINFIH+FWPSLLK+  
Sbjct: 510  IQNIKQILGLQQGKQYDSVKGLRYGHLMIMTDQDHDGSHIKGLLINFIHTFWPSLLKIPS 569

Query: 1625 FMVEFITPIVKASHKN-GTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGK 1801
            F+VEFITPIVKA++K  G V SFYTMPEYEAWKESL GNA+ W+IKYYKGLGTST++EGK
Sbjct: 570  FLVEFITPIVKATYKKTGKVTSFYTMPEYEAWKESLRGNASSWSIKYYKGLGTSTSQEGK 629

Query: 1802 EYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSD 1981
            EYF+ L++HKK FVW+DEQDG++IELAFSKKKIEARKNWLRQFE GT+LD  E+ I YSD
Sbjct: 630  EYFQDLQRHKKDFVWSDEQDGDAIELAFSKKKIEARKNWLRQFEPGTHLDQNEKLISYSD 689

Query: 1982 FVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAY 2161
            FVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN +KE K+ QF+GYVSEHSAY
Sbjct: 690  FVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKELKIGQFAGYVSEHSAY 749

Query: 2162 HHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFL 2341
            HHGEQSL +TI+GMAQDFVGSNNINL QPNGQFGTR++GGKD AS RYIYT LSPITRFL
Sbjct: 750  HHGEQSLATTIIGMAQDFVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTKLSPITRFL 809

Query: 2342 FPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVR 2521
            FPK            GQSIEP WY+PIIPMVLVNGSEGIGTGWSSY+PNYNPRD+V NVR
Sbjct: 810  FPKEDDLVLDYLTDDGQSIEPTWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVKNVR 869

Query: 2522 RLLNDEPMRPMEPWYRGFKGLIEKSAQKETG-VTYTISGIIEEVDITTLRITELPIRSWT 2698
            RLLN+EPM PM PWYRGFKGLIEK+A KETG +TYT++GI+EE+D TT+ ITELPIR WT
Sbjct: 870  RLLNNEPMVPMNPWYRGFKGLIEKTAVKETGAITYTVTGIMEEIDSTTVAITELPIRRWT 929

Query: 2699 ADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXX 2878
             DY EFL+++  G DK KEPFI+D R Y+DDV VHFEV LSEENM+ AKQEG        
Sbjct: 930  LDYKEFLESLETGNDKVKEPFIKDFREYSDDVSVHFEVTLSEENMIIAKQEGLDKKFKLA 989

Query: 2879 XXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXV 3058
              ISTSNMHLFD  G IKKYDTPEQILE+FFHLR+ +YEKRKK                V
Sbjct: 990  TSISTSNMHLFDHKGVIKKYDTPEQILEEFFHLRITYYEKRKKALLDTLELELLKLDNKV 1049

Query: 3059 RFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXX 3238
            RFIL VV+G IIVN R+ A+LFLEL +KGFTPFPK+TKGI AA AG T +          
Sbjct: 1050 RFILGVVEGRIIVNKRKGAELFLELKEKGFTPFPKETKGIGAATAGVTEEAEESEETAEV 1109

Query: 3239 TVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDAL 3418
             + GV KASDY+YL+SMSI SLTLEKVQ+LCA+K+K +  + ELRS S   LW +DLDAL
Sbjct: 1110 VIGGV-KASDYDYLISMSIASLTLEKVQKLCAEKEKHEKVVVELRSCSPSSLWNKDLDAL 1168

Query: 3419 EKQLDELDQKDVEAANMQEKIRRR--NTGAAVPSKAPKKPRKNNAIKGPTVAANDADADV 3592
            EK+LDEL+++D EA   ++K + +  N GAA   KAPKKPRKNN    P+ A        
Sbjct: 1169 EKKLDELEKQDAEAEVTRKKNKEKAGNGGAAAAKKAPKKPRKNNT--KPSAAIE------ 1220

Query: 3593 GTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXXKDRLAAYNLDSSPDQ 3772
               S  +D+                   AK  +V           KDRLAAYNLDSSP+ 
Sbjct: 1221 ---SMPIDSETVQEVPKPKPKRRQQKSTAKTVSVESDEDEAVIALKDRLAAYNLDSSPET 1277

Query: 3773 TFMETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDDGDFQMV 3952
            + METE+V  E+   K P KRA   K    +                  ED DD +F+  
Sbjct: 1278 SAMETETVV-EIAAAKGPKKRAGAAKKPLKLDSD--------------EEDTDDENFEND 1322

Query: 3953 EVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKPVVNA--SPEK 4126
            +                                Q KSL+SQKLI+++L P  NA  SPEK
Sbjct: 1323 KAPRGKKGGGGGRKPAANATKTKAITVRKKGDAQNKSLLSQKLISELLPPATNAVNSPEK 1382

Query: 4127 KVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEMNEVPVARNRPKRENRS 4306
            KVRK+R SPFNKKSGS+L ++        GS DSS   + E       VAR RPKRENR+
Sbjct: 1383 KVRKIRPSPFNKKSGSLLNKSE---TSGSGSQDSSSGASAEDF-----VARARPKRENRA 1434

Query: 4307 KVQYV 4321
            +V YV
Sbjct: 1435 RVVYV 1439


>gb|OVA19386.1| DNA topoisomerase II [Macleaya cordata]
          Length = 1515

 Score = 1862 bits (4822), Expect = 0.0
 Identities = 974/1480 (65%), Positives = 1098/1480 (74%), Gaps = 44/1480 (2%)
 Frame = +2

Query: 14   KTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFDEI 193
            KTIEE YQKKTQLEHILLRPDTY+GSIEKHT  LWV+E GEM  RP+SYVPGLYKIFDEI
Sbjct: 28   KTIEETYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYEGGEMVYRPVSYVPGLYKIFDEI 87

Query: 194  LVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLLTS 373
            LVNAADNKQRDP+MD VKVDID E N ISVYNNGDGVP+EIHQEEGVYVPE+IFGHLLTS
Sbjct: 88   LVNAADNKQRDPSMDSVKVDIDVEQNCISVYNNGDGVPVEIHQEEGVYVPELIFGHLLTS 147

Query: 374  SNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSITK 553
            SNYDD VKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVF+ NMG KS+P+ITK
Sbjct: 148  SNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFTNNMGTKSEPNITK 207

Query: 554  CKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPVKT 733
            CK  ENWTKVSFKPDLAKFNMTHLEDDVVALMKKRV+D+AG LGK VKVELNG RVPVK+
Sbjct: 208  CKESENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVIDMAGCLGKTVKVELNGQRVPVKS 267

Query: 734  FTDYVDLYLKSANKTRDEPLPRII---------------------------EKANNRWEV 832
            F DYV+LY++SA+K R + LPR +                           EK N+RWE+
Sbjct: 268  FLDYVNLYVQSASKNRPDSLPRFVSDKFESTHSNLFPFRILKQFDFSNRITEKVNDRWEI 327

Query: 833  CVSLSEGQFQQVSFVNGINTIKGGTHVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXL 1012
            CVSLSEGQFQQVSFVNGI TIKGGTHV+YVT+QIT                        L
Sbjct: 328  CVSLSEGQFQQVSFVNGIATIKGGTHVDYVTNQITNHVMTIVNKKNKNANLKAHTVKNHL 387

Query: 1013 WVFVNTLIDNPAFDSQTKETLTTRQGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQS 1192
            WVFVN LIDNPAFDSQTKETLTTRQGSFG+KCELS EFLKKV KSG+VE+LLSWADFKQS
Sbjct: 388  WVFVNALIDNPAFDSQTKETLTTRQGSFGTKCELSQEFLKKVAKSGVVESLLSWADFKQS 447

Query: 1193 KELKKTDGSKRQNVN-IPKLDDANDAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLY 1369
            K+LKKTDG+KRQ +  I KL+DANDAGG+NSDKCTLILTEGDSAKALA+AG+S VGRN Y
Sbjct: 448  KDLKKTDGAKRQRITGITKLEDANDAGGRNSDKCTLILTEGDSAKALAMAGISVVGRNYY 507

Query: 1370 GVFPLKGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDH 1549
            GVFPL+GKLLNVREAS KQIM+NAEIQ+IKQILGLQHGK+YDSVK LRYG LMIMTDQDH
Sbjct: 508  GVFPLRGKLLNVREASHKQIMENAEIQSIKQILGLQHGKEYDSVKSLRYGHLMIMTDQDH 567

Query: 1550 DGSHIKGLLINFIHSFWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESL 1729
            DGSHIKGLLINFIHSFWPSLLK+  F++EFITPIVKA+HKNG V+SFY+MPEYE WKESL
Sbjct: 568  DGSHIKGLLINFIHSFWPSLLKIPSFLIEFITPIVKATHKNGKVMSFYSMPEYEQWKESL 627

Query: 1730 NGNATGWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEAR 1909
             GNA+GW+IKYYKGLGTST+KEGKEYFK L KH+K F+W DEQDG++I+LAFSKKKIEAR
Sbjct: 628  GGNASGWSIKYYKGLGTSTSKEGKEYFKDLEKHRKDFMWVDEQDGDAIDLAFSKKKIEAR 687

Query: 1910 KNWLRQFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCA 2089
            KNWLRQFE GTYLD KE+ IKYSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+
Sbjct: 688  KNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCS 747

Query: 2090 FKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTR 2269
            FKRN +KEAKVAQFSGYVSEHSAYHHGEQSL  TI+GMAQD+VGSNNINL QPNGQFGTR
Sbjct: 748  FKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMAQDYVGSNNINLLQPNGQFGTR 807

Query: 2270 NKGGKDAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGS 2449
            ++GGKD AS RYIYT LSPITRFLFPK            GQSIEP WY+P+IP VLVNGS
Sbjct: 808  HQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYLNEDGQSIEPTWYVPVIPTVLVNGS 867

Query: 2450 EGIGTGWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTI 2629
            EGIGTGWS Y+PNYNPRD+V NV+RLLN EPM PM+PWY+GFKG IEK+A KE GV+YT+
Sbjct: 868  EGIGTGWSCYIPNYNPRDIVENVKRLLNGEPMEPMDPWYKGFKGRIEKTATKEGGVSYTV 927

Query: 2630 SGIIEEVDITTLRITELPIRSWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFE 2809
            SGIIEEV+ TTLRI+ELP+R WT DY EFL+++M G DK KEPFI+D R +NDD  VHFE
Sbjct: 928  SGIIEEVNETTLRISELPVRRWTQDYKEFLESIMTGNDKIKEPFIKDYREHNDDTTVHFE 987

Query: 2810 VILSEENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQF 2989
            VILSEEN++ AKQEG          +STSNMHLFD  G IKKYD PEQILE+FFHLRL+F
Sbjct: 988  VILSEENLVMAKQEGLLKKFKLTTTVSTSNMHLFDPKGVIKKYDNPEQILEEFFHLRLEF 1047

Query: 2990 YEKRKKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKT 3169
            YEKRK+V               VRFIL VVKGEIIV+NR+RADLFLEL QKGFTPFPKKT
Sbjct: 1048 YEKRKRVLLENLELELLKLDNKVRFILGVVKGEIIVSNRKRADLFLELQQKGFTPFPKKT 1107

Query: 3170 KGIDAAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKL 3349
            K ++A +AGAT DT              V+ASDYEYLLSM+IG+LTLEKVQELC DKQ+L
Sbjct: 1108 KLVEAVVAGATEDTEENEDNSEALSSRGVRASDYEYLLSMAIGTLTLEKVQELCNDKQRL 1167

Query: 3350 DHELEELRSTSSKILWMRDLDALEKQLDELDQKDVEAANMQEKIR---RRNTGAAVPSKA 3520
            D E++ELR  +SK LW +DLDALEK+ DE D+ D +A   ++ ++    +  G       
Sbjct: 1168 DGEVDELRRATSKSLWKKDLDALEKEFDEQDKNDSKAEEARKVMKSKVMKEAGMKDSKPV 1227

Query: 3521 PKKPRKNNAIKGPTVAANDADADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV- 3697
             K PRKNN  K    AA  A A V +T   M+  N                 AKK     
Sbjct: 1228 AKNPRKNNTKKVNNPAAVAASAQVSST---MEIENISEAAKPKGRGGPRKAPAKKGKPAL 1284

Query: 3698 ----XXXXXXXXXXKDRLAAYNLDSSPDQT------FMETESVAQEVLKMKAPSKRATVR 3847
                          K+RLAAYNLDSSP+Q+       METES      K K  SK  + +
Sbjct: 1285 VDSDDEDDDEILELKERLAAYNLDSSPEQSSAGPVAAMETESGIVRA-KNKETSKMVSAQ 1343

Query: 3848 KGKSTMTISXXXXXXXXXXXPAISEDGDDGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXX 4027
            K  +   IS             I E+ +D + ++V                         
Sbjct: 1344 KKATITEISDDEDNRNDEQMKTIMEN-EDFEPEVVVPAGRKGGKRGQTKPAANPKAAKPV 1402

Query: 4028 XXXXXXXXQGKSLVSQKLITDVLKPV--VNASPEKKVRKMRESPFNKKSGSVLGRARGPV 4201
                      K L++Q LITD+LKP   V  SPEKKVRKMR SPFNKKSGS+LGR    V
Sbjct: 1403 TVARKRGPTKKQLLNQTLITDILKPAENVGVSPEKKVRKMRASPFNKKSGSLLGR----V 1458

Query: 4202 VESEGSIDSSPSVNLEVEMNEVPVARNRPKRENRSKVQYV 4321
             + +       S        EV   R RP+R NR+  +YV
Sbjct: 1459 AKEDEEESPMGSEQQSGSSGEVVATRARPQRANRTVAKYV 1498


>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2 [Vitis vinifera]
          Length = 1489

 Score = 1847 bits (4785), Expect = 0.0
 Identities = 966/1463 (66%), Positives = 1105/1463 (75%), Gaps = 27/1463 (1%)
 Frame = +2

Query: 14   KTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFDEI 193
            KTIEE YQKK+QLEHILLRPDTYIGSIEKHT  LWVFE+ EM +R +SYVPGLYKIFDEI
Sbjct: 24   KTIEETYQKKSQLEHILLRPDTYIGSIEKHTQALWVFENNEMVHRSVSYVPGLYKIFDEI 83

Query: 194  LVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLLTS 373
            LVNAADNKQRDP+MD VKV ID E N ISVYNNGDGVP+EIHQEEGVYVPEMIFGHLLTS
Sbjct: 84   LVNAADNKQRDPSMDSVKVVIDVEKNCISVYNNGDGVPVEIHQEEGVYVPEMIFGHLLTS 143

Query: 374  SNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSITK 553
            SNYDD+VKKTTGGRNGYGAKLTNIFSTEFVI+TADG+RQKKYKQVFS NMGKKS+P ITK
Sbjct: 144  SNYDDDVKKTTGGRNGYGAKLTNIFSTEFVIETADGRRQKKYKQVFSNNMGKKSEPVITK 203

Query: 554  CKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPVKT 733
            CK  ENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVD+AG LGK VKVELNG R+PVK+
Sbjct: 204  CKERENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDIAGCLGKTVKVELNGQRIPVKS 263

Query: 734  FTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGTHV 913
            F DYV+LYL+SA K+R E LPRI EK N RWE+CVSLSEGQFQQVSFVN I TIKGGTHV
Sbjct: 264  FNDYVNLYLQSAAKSRPESLPRIAEKVNERWEICVSLSEGQFQQVSFVNSIATIKGGTHV 323

Query: 914  EYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQGS 1093
            +YVT+QI                         LWVFVN LIDNPAFDSQTKETLT RQ S
Sbjct: 324  DYVTNQIANFVMSIVNKKNKNANIKAHTVKNHLWVFVNALIDNPAFDSQTKETLTIRQSS 383

Query: 1094 FGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDANDAG 1270
            FGSKCELS EFLKKV KSG+VE+LLSWAD+KQ+K+LKKTDG+KRQ +  I KL+DANDAG
Sbjct: 384  FGSKCELSQEFLKKVSKSGVVESLLSWADYKQNKDLKKTDGTKRQRLTGITKLEDANDAG 443

Query: 1271 GKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAEIQ 1450
            G+NS+KCTLILTEGDSAKALA+AG+S VGRN YGVFPL+GKLLNVR+A  KQI++NAEIQ
Sbjct: 444  GRNSEKCTLILTEGDSAKALAMAGISVVGRNHYGVFPLRGKLLNVRDAQKKQILENAEIQ 503

Query: 1451 NIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKGFM 1630
            NIKQILGLQ GK+YDS+K LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+  F+
Sbjct: 504  NIKQILGLQQGKEYDSIKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFL 563

Query: 1631 VEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGKEYF 1810
            VEFITPIVKA+H+NG VLSFY+MPEYE+WKESL GNA+GW+IKYYKGLGTST+KEGKEYF
Sbjct: 564  VEFITPIVKATHRNGRVLSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKEYF 623

Query: 1811 KQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSDFVN 1990
            K L KHKK F+W DE+DG++IELAFSKKKIE RKNWLRQF+ GTYLD KE+ IKYSDFVN
Sbjct: 624  KDLGKHKKDFMWVDEKDGDAIELAFSKKKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVN 683

Query: 1991 KELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHG 2170
            KELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN IKEAK+AQFSGYVSEHSAYHHG
Sbjct: 684  KELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHG 743

Query: 2171 EQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFLFPK 2350
            EQSL STI+GMAQDFVGSNNINL  PNGQFGTR++GGKD AS RYIYT LSPITRFLFPK
Sbjct: 744  EQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPK 803

Query: 2351 XXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVRRLL 2530
                        GQSIEP WY+P IPMVLVNGSEGIGTGWSS +PNYNPRD++ANVRRLL
Sbjct: 804  DDDILLDYLNEDGQSIEPTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLL 863

Query: 2531 NDEPMRPMEPWYRGFKGLIEKS-AQKETGVTYTISGIIEEVDITTLRITELPIRSWTADY 2707
            N E M PM+PWYRGF+G IEK+   K+  V YT+ GIIEEV+ TTLRI+ELP+R WT DY
Sbjct: 864  NGEMMEPMDPWYRGFRGTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVRKWTQDY 923

Query: 2708 NEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXXXI 2887
             EFL+++M G DK K+PFI+D + +NDD  VHFEVI+SEEN++ AKQEG          I
Sbjct: 924  KEFLESIMTGNDKIKDPFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKI 983

Query: 2888 STSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVRFI 3067
            STSNMHLFDSNGTIKKY+TPEQILE+FFHLRL+FYEKRK+V               VRFI
Sbjct: 984  STSNMHLFDSNGTIKKYETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFI 1043

Query: 3068 LAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXTVK 3247
            L VV+GEIIV+NR+RADLF ELHQKGFTPFPKK+K ++ A+AGAT DT           K
Sbjct: 1044 LGVVRGEIIVSNRKRADLFHELHQKGFTPFPKKSKSVEIAVAGATDDTEEAEENTDAVSK 1103

Query: 3248 GVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALEKQ 3427
            G V+A+DYEYLLSM+IG+LTLEKVQELCAD+ KL+  +++L+  + K LW+ DLDALE++
Sbjct: 1104 GGVRATDYEYLLSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERE 1163

Query: 3428 LDELDQKDVEAANMQEKIRRR---NTGAAVPSKAPKKPRKNNAIKGPTVAANDADADVGT 3598
            LDE D+ D  A   +++++ R     G  V  +APK PRKNN  K    A   A+    +
Sbjct: 1164 LDEQDKNDARAEETRKQLKSRVMSEAGMKVSRQAPKNPRKNN--KKANNAEPAAETMDVS 1221

Query: 3599 TSTAMDAGNXXXXXXXXXXXXXXXDAAKK-----TTVVXXXXXXXXXXKDRLAAYNLDSS 3763
             S+AM+  +                 AKK     + +           K+RLAAYNL+SS
Sbjct: 1222 ASSAMEMESVPEVVKPKGRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESS 1281

Query: 3764 PD-QTFMETESVAQEVLKMKAPSKRATVRKG--KSTMTISXXXXXXXXXXXPAISEDGDD 3934
            PD    ME E       + K PS+RA  +K    S   IS               +D DD
Sbjct: 1282 PDGSAAMEAEVPQVPAARKKEPSRRAAAQKKPLASFTEIS--------------DDDEDD 1327

Query: 3935 GDFQMVEV-------XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDV 4093
             DF++ EV                                      Q   L+ Q L+T++
Sbjct: 1328 EDFEVEEVSASDVKKKGGRKPAANAKAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEI 1387

Query: 4094 LKP--VVNASPEKKVRKMRESPFNKKSGSVLGRARGPVVES----EGSIDSSPSVNLEVE 4255
             KP   +  SPEKKVRKMR SPFNKKSGSVLG + G   E+    E S  +S S +   E
Sbjct: 1388 FKPAETLGISPEKKVRKMRASPFNKKSGSVLG-STGEEDETAETEENSGSASTSNSSGGE 1446

Query: 4256 MNEVPV-ARNRPKRENRSKVQYV 4321
             NEV + AR RP+RENR + +YV
Sbjct: 1447 SNEVVMPARTRPQRENRVQTRYV 1469


>emb|CDP07797.1| unnamed protein product [Coffea canephora]
          Length = 1486

 Score = 1836 bits (4755), Expect = 0.0
 Identities = 963/1460 (65%), Positives = 1092/1460 (74%), Gaps = 24/1460 (1%)
 Frame = +2

Query: 14   KTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFDEI 193
            KTIEE YQKK+QLEHILLRPDTYIGSIEKH+  LWVFE+  M +R ISYVPGLYKIFDEI
Sbjct: 25   KTIEETYQKKSQLEHILLRPDTYIGSIEKHSQTLWVFENDAMVHRQISYVPGLYKIFDEI 84

Query: 194  LVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLLTS 373
            LVNAADNKQRDP MD VK+ I+ E N ISVYNNGDGVP+E+HQEEGVYVPE+IFGHLLTS
Sbjct: 85   LVNAADNKQRDPRMDSVKIVINVEENFISVYNNGDGVPVEVHQEEGVYVPELIFGHLLTS 144

Query: 374  SNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSITK 553
            SNYDD VKKTTGGRNGYGAKLTNIFSTEFVI++ADG+RQKKYKQVFS NMG KS P I+K
Sbjct: 145  SNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIESADGRRQKKYKQVFSNNMGNKSQPIISK 204

Query: 554  CKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPVKT 733
            CK  ENWTKV++KPDLAKFNMTHLEDDVVALMKKRVVDLAG LGK VKVELNG RVPVK+
Sbjct: 205  CKESENWTKVTYKPDLAKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGQRVPVKS 264

Query: 734  FTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGTHV 913
            F+DY DLYL+SA KTR +PLPRI+EK N RWEVC SLSEGQFQQVSFVNGI TIKGGTHV
Sbjct: 265  FSDYCDLYLQSAAKTRPDPLPRIVEKVNERWEVCASLSEGQFQQVSFVNGIATIKGGTHV 324

Query: 914  EYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQGS 1093
            +YVT+QIT                        LWVFVN LIDNPAFDSQTKETLT RQ S
Sbjct: 325  DYVTNQITNHIIGIVNKKNKNANLKAHSVKNHLWVFVNALIDNPAFDSQTKETLTLRQSS 384

Query: 1094 FGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDANDAG 1270
            FGSKCELS EFLKKV KSG+VE LLSWADFKQSK+LKKTDG+KRQ +  I KL+DANDAG
Sbjct: 385  FGSKCELSQEFLKKVAKSGVVENLLSWADFKQSKDLKKTDGTKRQRITGITKLEDANDAG 444

Query: 1271 GKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAEIQ 1450
            GKNSD+CTLILTEGDSAKALA+AG+S VGRN YGVFPL+GKLLNVREAS KQIM NAEIQ
Sbjct: 445  GKNSDRCTLILTEGDSAKALAMAGISVVGRNFYGVFPLRGKLLNVREASHKQIMDNAEIQ 504

Query: 1451 NIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKGFM 1630
             IKQILGLQHGK YDSVK LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+  F+
Sbjct: 505  YIKQILGLQHGKVYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFL 564

Query: 1631 VEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGKEYF 1810
            VEFITPIVKA+HKNG VLSFYTMPEYE+WKESL+GNATGW+IKYYKGLGTST+KEGKEYF
Sbjct: 565  VEFITPIVKATHKNGRVLSFYTMPEYESWKESLSGNATGWSIKYYKGLGTSTSKEGKEYF 624

Query: 1811 KQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSDFVN 1990
            K L KHKK F+W D+ DGE+IELAFSKKKIEARKNWLRQFE GTYLD KE+ IKYSDF+N
Sbjct: 625  KDLGKHKKDFIWVDDNDGEAIELAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFIN 684

Query: 1991 KELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHG 2170
            KELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN +KEAKVAQFSGYVSEHSAYHHG
Sbjct: 685  KELILFSLADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHG 744

Query: 2171 EQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFLFPK 2350
            EQSL S I+GMAQDFVGSNNINL QPNGQFGTRN+GGKD AS RY+YT LSPITR LFPK
Sbjct: 745  EQSLASAIIGMAQDFVGSNNINLLQPNGQFGTRNQGGKDHASARYVYTRLSPITRSLFPK 804

Query: 2351 XXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVRRLL 2530
                        GQSIEP WYMPIIPMVLVNGSEGIGTGWSSY+PNYNPRD++ N+RRLL
Sbjct: 805  DDDILLDYLNEDGQSIEPTWYMPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIIGNIRRLL 864

Query: 2531 NDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTADYN 2710
            N+EPM PMEPWY+GF+G IEK+A KE G +YT+SGI+EEVD TT+R+TELP+R WT DY 
Sbjct: 865  NNEPMEPMEPWYKGFRGTIEKTATKEAGASYTVSGIVEEVDETTIRVTELPVRKWTQDYK 924

Query: 2711 EFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXXXIS 2890
            EFL+++M G +K K+PFI++ R + DD  V+ ++I+SEEN++ AKQEG          IS
Sbjct: 925  EFLESIMMGNEKVKDPFIKEFRDHTDDTTVYLDIIMSEENLLMAKQEGLLKKFKLTTTIS 984

Query: 2891 TSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVRFIL 3070
            TSNMHLFDS G IKK+D PEQILE+FFHLRL+FYEKRKKV               VRFIL
Sbjct: 985  TSNMHLFDSQGIIKKFDNPEQILEEFFHLRLEFYEKRKKVLLDNLQLELLKLDNKVRFIL 1044

Query: 3071 AVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXTVKG 3250
            AVV+G IIV+NR+RADLFLEL +KGFTPFPKK K ++AA+AG+  D              
Sbjct: 1045 AVVEGSIIVSNRKRADLFLELKEKGFTPFPKK-KSVEAAVAGSIEDAEETEESSEVATSK 1103

Query: 3251 VVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALEKQL 3430
             V+ASDYEYL+SM+IGSLTLEKVQELCAD+ KL  E+++L   + K LW +DLDALE QL
Sbjct: 1104 GVRASDYEYLISMAIGSLTLEKVQELCADRDKLKGEVDDLIKATPKSLWTKDLDALESQL 1163

Query: 3431 DELDQKDVEAANMQEKIR---RRNTGAAVPSKAPKKPRKNNAIKGPTVAANDADADVGTT 3601
            DE D  D +A   ++++R    ++ G     +APK PRK N  K           ++ ++
Sbjct: 1164 DEQDISDAQAEAARKEMRSKAMKDDGPKPTRQAPKNPRKYNK-KASNTEPTTEPMEI-SS 1221

Query: 3602 STAMDAGNXXXXXXXXXXXXXXXDAAKKTTVV-------XXXXXXXXXXKDRLAAYNL-D 3757
            S+A++  N                 A+K                     KDRLAAYNL  
Sbjct: 1222 SSALETNNVVEVAKPKGKAGPKKAPARKGKTFSVLRDEDDEDDDEVLALKDRLAAYNLGS 1281

Query: 3758 SSPDQT-FMETESVAQEVLKMKAPSKRATVRKGKSTMT-ISXXXXXXXXXXXPAISEDGD 3931
            SSPDQ+  METE      +  + PSKRAT +K   ++T IS               E  D
Sbjct: 1282 SSPDQSETMETE------IPKREPSKRATTKKPLVSVTEISDDDDDQI--------EISD 1327

Query: 3932 DGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKP--V 4105
            D DF++ EV                               +   LV QKLIT+VLKP  V
Sbjct: 1328 DEDFEL-EVEAAPKEKGRKKTANSKAAKPTAAPKKRGQANKTSQLVGQKLITEVLKPADV 1386

Query: 4106 VNASPEKKVRKMRESPFNKKSGSVLGRAR-------GPVVESEGSIDSSPSVNLEVEMNE 4264
               SPEKKVR+MR SPFNKKSGSVL R          P  E +    +S +     E  +
Sbjct: 1387 SKISPEKKVRRMRPSPFNKKSGSVLERLSQQETDKISPESEEQEESPASNASGSTEESAQ 1446

Query: 4265 VPVARNRPKR-ENRSKVQYV 4321
            V V R RP+R  NR K +YV
Sbjct: 1447 VVVPRARPRRGGNRGKAKYV 1466


>ref|XP_008779357.2| PREDICTED: DNA topoisomerase 2 [Phoenix dactylifera]
          Length = 1378

 Score = 1834 bits (4751), Expect = 0.0
 Identities = 950/1369 (69%), Positives = 1063/1369 (77%), Gaps = 6/1369 (0%)
 Frame = +2

Query: 233  MDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLLTSSNYDDNVKKTTGG 412
            MD VKVDID   N ISVYNNGDGVP+EIHQEEGVYVPEMIFGHLLTSSNYDDNVKKTTGG
Sbjct: 1    MDSVKVDIDVAGNCISVYNNGDGVPVEIHQEEGVYVPEMIFGHLLTSSNYDDNVKKTTGG 60

Query: 413  RNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSITKCKAGENWTKVSFK 592
            RNGYGAKLTNIFSTEFVIQTADG+R+KKYKQVFSENMG+KS+PSITKCK  ENWTK++FK
Sbjct: 61   RNGYGAKLTNIFSTEFVIQTADGRRKKKYKQVFSENMGQKSEPSITKCKESENWTKITFK 120

Query: 593  PDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPVKTFTDYVDLYLKSAN 772
            PDLAKFNMTHLEDDV ALMKKRVVDLAGTLGK VKVELNG R+PVK+F+DYV+LYL+S +
Sbjct: 121  PDLAKFNMTHLEDDVAALMKKRVVDLAGTLGKSVKVELNGQRIPVKSFSDYVNLYLQSVS 180

Query: 773  KTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGTHVEYVTSQITXXXXX 952
            K+R EPLPRI EK N+RWE+CVSLSEGQFQQVSFVNGI T KGGTHVEYVT+QIT     
Sbjct: 181  KSRPEPLPRISEKVNDRWEICVSLSEGQFQQVSFVNGIATTKGGTHVEYVTNQITSHVMN 240

Query: 953  XXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQGSFGSKCELSGEFLK 1132
                               LWVFVN LIDNPAFDSQTKETLTTRQGSFGSKCELS EFLK
Sbjct: 241  IVNKKNKNANLKAHNVRSHLWVFVNALIDNPAFDSQTKETLTTRQGSFGSKCELSQEFLK 300

Query: 1133 KVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDANDAGGKNSDKCTLILTE 1309
            KV KSG+V +LLSWADFKQSKELKKTDG+KRQ +  IPKL+DANDAGG+NS+KCTLILTE
Sbjct: 301  KVAKSGVVNSLLSWADFKQSKELKKTDGTKRQRITGIPKLEDANDAGGRNSEKCTLILTE 360

Query: 1310 GDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAEIQNIKQILGLQHGKQ 1489
            GDSAKALA+AG+S VGRN YGVFPL+GKLLNVREAS KQIM+NAEIQNIKQILGLQHGK+
Sbjct: 361  GDSAKALAMAGISVVGRNYYGVFPLRGKLLNVREASHKQIMENAEIQNIKQILGLQHGKE 420

Query: 1490 YDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKGFMVEFITPIVKASH- 1666
            YDS KGLRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLK+  FMVEFITPIVKA+H 
Sbjct: 421  YDSTKGLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKIPSFMVEFITPIVKATHS 480

Query: 1667 KNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGKEYFKQLRKHKKSFVW 1846
            KN TVL FY+MPEYEAWKE L GNA+GW+IKYYKGLGTST+KEGKEYF  + KHKK F+W
Sbjct: 481  KNKTVLPFYSMPEYEAWKERLGGNASGWSIKYYKGLGTSTSKEGKEYFHDIDKHKKDFIW 540

Query: 1847 ADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSDFVNKELILFSRADLQ 2026
             D+QDG++IELAFSKKKIEARKNWLR FE GTYLD +++ IKYSDFVNKELILFS ADLQ
Sbjct: 541  VDDQDGDAIELAFSKKKIEARKNWLRHFETGTYLDQRQKHIKYSDFVNKELILFSMADLQ 600

Query: 2027 RSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHGEQSLVSTIVGMA 2206
            RSIPS VDGLKPGQRKILFC+FKRN +KEAKVAQFSGYVSEHSAYHHGEQSL STI+GMA
Sbjct: 601  RSIPSTVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIIGMA 660

Query: 2207 QDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFLFPKXXXXXXXXXXXX 2386
            QDFVGSNNINL QPNGQFGTR++GGKD AS RYIYT LSP+TRFLFPK            
Sbjct: 661  QDFVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPLTRFLFPKDDDMLLDYLNED 720

Query: 2387 GQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVRRLLNDEPMRPMEPWY 2566
            GQSIEP WYMPIIP+VLVNGSEGIGTGWSS+VPNYNPRD+VANVRRLLNDEPM+PM+PWY
Sbjct: 721  GQSIEPTWYMPIIPLVLVNGSEGIGTGWSSFVPNYNPRDIVANVRRLLNDEPMQPMDPWY 780

Query: 2567 RGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTADYNEFLDAMMKGTDK 2746
            RGFKGLIEKSA KE GVTYTI+G+IEEVD TTLRITELPIR WT DY EFL++MM G DK
Sbjct: 781  RGFKGLIEKSATKEAGVTYTITGLIEEVDSTTLRITELPIRRWTQDYKEFLESMMTGNDK 840

Query: 2747 FKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXXXISTSNMHLFDSNGT 2926
             KEPFI+D R +NDD+ VHFE+IL+EE +  AK+EG          IST+NMHLFDS G 
Sbjct: 841  IKEPFIKDYREHNDDINVHFEIILTEEKLKMAKEEGLERKFKLTTTISTTNMHLFDSEGV 900

Query: 2927 IKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVRFILAVVKGEIIVNNR 3106
            IKKYDTPEQILEDFFHLRL++Y KRKKV               VRFIL VV+GEIIV+NR
Sbjct: 901  IKKYDTPEQILEDFFHLRLEYYAKRKKVLLDNLEMDLLKLDNKVRFILGVVRGEIIVSNR 960

Query: 3107 RRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXTVKGVVKASDYEYLLS 3286
            +RADLFLEL QKGFTPFPKK+KGIDAAIAGAT +          + +   +A+DYEYLLS
Sbjct: 961  KRADLFLELQQKGFTPFPKKSKGIDAAIAGATEE-----DDNEESPEVAARATDYEYLLS 1015

Query: 3287 MSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALEKQLDELDQKDVEAAN 3466
            M+IG+LT EKVQELCAD++KL+ E+EEL+ +S + LWM+DLD  E++LDEL++KD E   
Sbjct: 1016 MAIGTLTWEKVQELCADRKKLEGEVEELKKSSPRDLWMKDLDDFERELDELERKDAEEGM 1075

Query: 3467 MQEKIRRRNTGAAVPSKAPKKPRKNNAIKGPTVAANDADADVGTTSTAMDAGNXXXXXXX 3646
             +E   +  TGAAV  + PKKPRKNN        AN++ +    TST  DAGN       
Sbjct: 1076 KRETRTKNITGAAVSRQGPKKPRKNN--------ANNSSSISNVTST--DAGNAPEPSKL 1125

Query: 3647 XXXXXXXXDAAKKTTVV-XXXXXXXXXXKDRLAAYNLDSSPDQTFMETE-SVAQEVLKMK 3820
                      AKK  VV           KDRLAAYNLDSSPDQ+ ME E +++Q   + K
Sbjct: 1126 KARGGAKKAPAKKVMVVESDEDEEVLALKDRLAAYNLDSSPDQSAMEAEAALSQREHRKK 1185

Query: 3821 APSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDDGDFQMVEVXXXXXXXXXXXXXX 4000
             PSKR  +RK  ST T             P + ED DD DF++ E               
Sbjct: 1186 EPSKRTALRKAPSTFT-EISDGDDVEDNMPIVGED-DDEDFELAEAPKGGQARGRKPANE 1243

Query: 4001 XXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKPVVNA--SPEKKVRKMRESPFNKKSGS 4174
                             Q K ++SQKLIT+VLKPV NA  SP+KKVRKMR SPFNKKSG 
Sbjct: 1244 KAKRGKATTTTRKRGAAQSKPVLSQKLITEVLKPVENAGISPDKKVRKMRASPFNKKSGP 1303

Query: 4175 VLGRARGPVVESEGSIDSSPSVNLEVEMNEVPVARNRPKRENRSKVQYV 4321
            VLGR      +SE S   S S     EMNEVPVA  RPKR NR +  Y+
Sbjct: 1304 VLGRTGSSPTDSEES--GSHSSGSPAEMNEVPVAAPRPKRGNRIRAVYM 1350


>gb|EOY18137.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
          Length = 1473

 Score = 1817 bits (4707), Expect = 0.0
 Identities = 959/1451 (66%), Positives = 1085/1451 (74%), Gaps = 15/1451 (1%)
 Frame = +2

Query: 14   KTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFDEI 193
            KTIEE YQKKTQLEHILLRPDTYIGSIE+HT  LWV+E+ EM +R I YVPGLYKIFDEI
Sbjct: 21   KTIEETYQKKTQLEHILLRPDTYIGSIEQHTQRLWVYENDEMVHRDIKYVPGLYKIFDEI 80

Query: 194  LVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLLTS 373
            LVNAADNKQRDP+MD VKV ID E NLISVYNNGDGVP+E+HQEEGVYVPE+IFGHLLTS
Sbjct: 81   LVNAADNKQRDPSMDSVKVVIDAEQNLISVYNNGDGVPVEVHQEEGVYVPELIFGHLLTS 140

Query: 374  SNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSITK 553
            SNYDD VKKTTGGRNGYGAKLTNIFSTEF+I+TADGKRQKKYKQVFS NMGKKS+P I+K
Sbjct: 141  SNYDDTVKKTTGGRNGYGAKLTNIFSTEFIIETADGKRQKKYKQVFSNNMGKKSEPVISK 200

Query: 554  CKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPVKT 733
            CK  ENWTKV+FKPDLAKFNMTHLE+DVVALMKKRV D+AG LGK VKVELNG RVPVK+
Sbjct: 201  CKEAENWTKVTFKPDLAKFNMTHLEEDVVALMKKRVFDVAGCLGKTVKVELNGKRVPVKS 260

Query: 734  FTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGTHV 913
            F DYV LYL +A+KT+ EPLPR++EK N RWEV VSLS+GQFQQVSFVNGI TIKGGTHV
Sbjct: 261  FLDYVSLYLSAASKTKTEPLPRLLEKVNERWEVGVSLSDGQFQQVSFVNGIATIKGGTHV 320

Query: 914  EYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQGS 1093
            +YVT+QI+                        LWVFVN LIDNPAFDSQTKETLT RQ S
Sbjct: 321  DYVTNQISNYVMNIVNKKNKNANVKAHNVKNHLWVFVNALIDNPAFDSQTKETLTLRQSS 380

Query: 1094 FGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDANDAG 1270
            FGSKCELS +FLKKV K G+V+ LLSWA+FK SK+LKKTDG+K  ++  IPKLDDAN+AG
Sbjct: 381  FGSKCELSEDFLKKVAKCGVVDNLLSWAEFKHSKDLKKTDGAKTGSIRGIPKLDDANEAG 440

Query: 1271 GKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAEIQ 1450
            G+NSDKCTLILTEGDSAKALAVAG++ VGRN YGVFPL+GKLLNVREAS KQ+M NAEIQ
Sbjct: 441  GRNSDKCTLILTEGDSAKALAVAGLAVVGRNHYGVFPLRGKLLNVREASHKQLMDNAEIQ 500

Query: 1451 NIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKGFM 1630
            N+K+ILGLQ GK+Y +VK LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKV  FM
Sbjct: 501  NLKRILGLQQGKEYSNVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFM 560

Query: 1631 VEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGKEYF 1810
            VEFITPIVKA+HK   VLSFY+MPEYE WKESL GNA GW+IKYYKGLGTST+KEGK+YF
Sbjct: 561  VEFITPIVKATHKTKGVLSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYF 620

Query: 1811 KQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSDFVN 1990
            K L KH+K FVW DEQDGE+IELAFSKKKIEARKNWLRQFE GT+LD  ++ IKYS+F+N
Sbjct: 621  KNLDKHRKEFVWQDEQDGEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFIN 680

Query: 1991 KELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHG 2170
            KELILFS ADLQRSIPSM+DGLKPGQRKILFC+FKRN +KEAKVAQFSGYVSEHSAYHHG
Sbjct: 681  KELILFSMADLQRSIPSMIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHG 740

Query: 2171 EQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFLFPK 2350
            EQSL STIVGMAQDFVGSNNINL  P GQFGTRN+GGKDAAS RYI+T LSPITR+LFPK
Sbjct: 741  EQSLASTIVGMAQDFVGSNNINLLNPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPK 800

Query: 2351 XXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVRRLL 2530
                        GQSIEP WY+PIIPMVLVNGSEGIGTGWSSY+PNYNPRD+VANVRRLL
Sbjct: 801  DDDGLLDYLNEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLL 860

Query: 2531 NDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTADYN 2710
            N E M PM PWYRGFKG IEK+A KE GVTYTI+GIIEEVD TTLRITELP+R WT DY 
Sbjct: 861  NGEQMEPMHPWYRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYR 920

Query: 2711 EFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXXXIS 2890
            EFL++++ G D    PFI++ R Y+DD  V FEVIL+EENMM AKQEG          IS
Sbjct: 921  EFLESIITGND----PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTIS 976

Query: 2891 TSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVRFIL 3070
            TSNMHLFDS G IKKYDTPEQILE+FFHLR +FYEKRKK+               VRFIL
Sbjct: 977  TSNMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFIL 1036

Query: 3071 AVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXTVKG 3250
             VVKGEIIVNNR+RADLFLEL  KGFTPFPKK K ++ A+AGAT DT         + KG
Sbjct: 1037 GVVKGEIIVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKG 1096

Query: 3251 VVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALEKQL 3430
             ++ASDY+YLLSM+IGSLTLEKVQELCAD+ KL  E+E+LR  + K LW++DLD LE QL
Sbjct: 1097 -LQASDYDYLLSMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQL 1155

Query: 3431 DELDQKDVEAANMQEKIR-RRNTGAAVPSKAPKKPRK-NNAIKGPTVAANDADADVGTTS 3604
            DE D K  +A    + ++ R   G     +APK PRK N   K         D    ++S
Sbjct: 1156 DEQD-KAAQAEEAAKLVKGRGEAGKRAQRQAPKIPRKINKKEKNAETVTETTDI---SSS 1211

Query: 3605 TAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXXKDRLAAYNLDSSPDQT-FM 3781
            +AM+                       +             ++RLA YNLDSSPD +  M
Sbjct: 1212 SAMETETAPAAVKPKGRGGSRKAKKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAM 1271

Query: 3782 ETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISE-DGDDGDFQMVEV 3958
            ETE V Q     K PSKRA   + K   ++S            +I E D +D D ++VEV
Sbjct: 1272 ETE-VPQVPAGKKEPSKRAAAARKKPATSLS--------EISESIGEIDINDEDLEVVEV 1322

Query: 3959 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQ-----GKSLVSQKLITDVLKPVVNA--S 4117
                                           +     GK    QKL+T++LKP  ++  S
Sbjct: 1323 AAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGIS 1382

Query: 4118 PEKKVRKMRESPFNKKSGSVLGRARGPV---VESEGSIDSSPSVNLEVEMNEVPVARNRP 4288
            PEKKVRKMR SPFNKKSGSVLGR    +    +SE +  SS       E+ E+  AR RP
Sbjct: 1383 PEKKVRKMRASPFNKKSGSVLGRVGKELESTTDSEETFGSSSMSADTEEVTEIVPARPRP 1442

Query: 4289 KRENRSKVQYV 4321
            +R NR +  YV
Sbjct: 1443 QRTNRKQTTYV 1453


>ref|XP_021295966.1| DNA topoisomerase 2 [Herrania umbratica]
          Length = 1475

 Score = 1817 bits (4706), Expect = 0.0
 Identities = 958/1453 (65%), Positives = 1085/1453 (74%), Gaps = 17/1453 (1%)
 Frame = +2

Query: 14   KTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFDEI 193
            KTIEE YQKKTQLEHILLRPDTYIGSIE+HT  LWV+E+ EM +R I YVPGLYKIFDEI
Sbjct: 21   KTIEETYQKKTQLEHILLRPDTYIGSIEQHTQRLWVYENDEMVHRDIKYVPGLYKIFDEI 80

Query: 194  LVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLLTS 373
            LVNAADNKQRDP+MD VKV ID E NLISVYN+GDGVP+E+HQEEGVYVPE+IFGHLLTS
Sbjct: 81   LVNAADNKQRDPSMDSVKVVIDEEQNLISVYNSGDGVPVEVHQEEGVYVPELIFGHLLTS 140

Query: 374  SNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSITK 553
            SNYDD VKKTTGGRNGYGAKLTNIFSTEFVI+TADGKRQKKYKQVFS NMG+KS+P I+K
Sbjct: 141  SNYDDTVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQKKYKQVFSNNMGEKSEPVISK 200

Query: 554  CKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPVKT 733
            CK  ENWTKV+FKPDLAKFNMTHLE+DVVALMKKRV DLAG LGK VKVELNG RVPVK+
Sbjct: 201  CKEAENWTKVTFKPDLAKFNMTHLEEDVVALMKKRVFDLAGCLGKTVKVELNGKRVPVKS 260

Query: 734  FTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGTHV 913
            F DYV LYL +A+KT+ EPLPR++EK N RWEVCVSLS+GQFQQVSFVNGI TIKGGTHV
Sbjct: 261  FLDYVSLYLSAASKTKTEPLPRLLEKVNERWEVCVSLSDGQFQQVSFVNGIATIKGGTHV 320

Query: 914  EYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQGS 1093
            +YVT+QI+                        LWVFVN LIDNPAFDSQTKETLT RQ S
Sbjct: 321  DYVTNQISNYVMNIVNKKNKNANVKAHNVKNHLWVFVNALIDNPAFDSQTKETLTLRQSS 380

Query: 1094 FGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDANDAG 1270
            FGSKCELS +FLKKV K G+V+ LLSWA+FK SK+LKKTDG+K  ++  IPKLDDAN+AG
Sbjct: 381  FGSKCELSEDFLKKVAKCGVVDNLLSWAEFKHSKDLKKTDGAKTGSIRGIPKLDDANEAG 440

Query: 1271 GKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAEIQ 1450
            G+NSDKCTLILTEGDSAKALAVAG++ VGRN YGVFPL+GKLLNVREAS KQ+M NAEIQ
Sbjct: 441  GRNSDKCTLILTEGDSAKALAVAGLAVVGRNHYGVFPLRGKLLNVREASHKQLMDNAEIQ 500

Query: 1451 NIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKGFM 1630
            N+K+ILGLQ GK+Y +VK LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKV  FM
Sbjct: 501  NLKRILGLQQGKEYTNVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFM 560

Query: 1631 VEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGKEYF 1810
            VEFITPIVKA+HK   VLSFY+MPEYE+WKE L GNA GW+IKYYKGLGTST+KEGK+YF
Sbjct: 561  VEFITPIVKATHKTKGVLSFYSMPEYESWKERLGGNAKGWSIKYYKGLGTSTSKEGKDYF 620

Query: 1811 KQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSDFVN 1990
            K L KHKK FVW  +QDGE+IELAFSKKKIEARKNWLRQFE GT+LD  ++ IKYS+F+N
Sbjct: 621  KNLDKHKKEFVWQGDQDGEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFIN 680

Query: 1991 KELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHG 2170
            KELILFS ADLQRSIPSM+DGLKPGQRKILFC+FKRN +KEAKVAQFSGYVSEHSAYHHG
Sbjct: 681  KELILFSMADLQRSIPSMIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHG 740

Query: 2171 EQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFLFPK 2350
            EQSL STIVGMAQDFVGSNNINL  P GQFGTRN+GGKDAAS RYI+T LSPITR+LFPK
Sbjct: 741  EQSLASTIVGMAQDFVGSNNINLLHPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPK 800

Query: 2351 XXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVRRLL 2530
                        GQSIEP WY+PIIPMVLVNGSEGIGTGWSSY+PNYNPRD+VANVRRLL
Sbjct: 801  DDDGVLDYLNEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLL 860

Query: 2531 NDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTADYN 2710
            NDE M PM PWYRGFKG IEK+A KE GVTYTI+G+IEEVD  TLRITELP+R WT DY 
Sbjct: 861  NDEQMEPMHPWYRGFKGNIEKTASKEAGVTYTITGVIEEVDEATLRITELPVRRWTQDYR 920

Query: 2711 EFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXXXIS 2890
            EFL++++ G D    PFI++ R Y+DD  V FEVIL+EENMM AKQEG          IS
Sbjct: 921  EFLESIITGND----PFIKEFRQYSDDTTVEFEVILTEENMMMAKQEGLLKKFKLTTTIS 976

Query: 2891 TSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVRFIL 3070
            TSNMHLFDS G IKKYDTPEQILE+FFHLR +FYEKRKK+               VRFIL
Sbjct: 977  TSNMHLFDSKGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFIL 1036

Query: 3071 AVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXTVKG 3250
             VVKGEIIVNNR+RADLFLEL  KGFTPFPKK K ++ A+AGAT DT         + KG
Sbjct: 1037 GVVKGEIIVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKG 1096

Query: 3251 VVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALEKQL 3430
             V+ASDY+YLLSM+IGSLTLEKVQELCAD+ KL  E+E+LR  + K LW++DLD LE QL
Sbjct: 1097 -VQASDYDYLLSMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQL 1155

Query: 3431 DELDQKDVEAANMQEKIR-RRNTGAAVPSKAPKKPRK-NNAIKGPTVAANDADADVGTTS 3604
            DE D K  +A    + ++ R   G     +APK PRK N   K        +D    ++S
Sbjct: 1156 DEQD-KAAQAEEAAKLVKGRAEAGKRAQRQAPKIPRKINKKEKNAETVTETSDI---SSS 1211

Query: 3605 TAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXXKDRLAAYNLDSSPDQT-FM 3781
            +AM+  N                    +             ++RLA YNLDSSPD +  M
Sbjct: 1212 SAMETENAPAAVKPKGRGGSRKAKKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAM 1271

Query: 3782 ETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISE-DGDDGDFQMVEV 3958
            ETE V       K PSKRA   + K   ++S            +I E D +D D  +VEV
Sbjct: 1272 ETE-VPLVPAGKKEPSKRAAATRKKPASSLS--------EISESIGEIDINDEDLDVVEV 1322

Query: 3959 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQ-------GKSLVSQKLITDVLKPVVNA- 4114
                                           +       GK    QKL+T++LKP  ++ 
Sbjct: 1323 EVAAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPAASGKKSQQQKLLTEMLKPAEDSG 1382

Query: 4115 -SPEKKVRKMRESPFNKKSGSVLGRA---RGPVVESEGSIDSSPSVNLEVEMNEVPVARN 4282
             SPEKKVRKMR SPFNKKSGSVLGR    +    +SE +  SS       E+ E+  AR 
Sbjct: 1383 ISPEKKVRKMRASPFNKKSGSVLGRVGKEQESTTDSEETFGSSSMSADTEEVTEIVPARP 1442

Query: 4283 RPKRENRSKVQYV 4321
            RP+R NR +  YV
Sbjct: 1443 RPQRTNRKQTTYV 1455


>ref|XP_007009327.2| PREDICTED: DNA topoisomerase 2 [Theobroma cacao]
          Length = 1473

 Score = 1814 bits (4699), Expect = 0.0
 Identities = 962/1453 (66%), Positives = 1086/1453 (74%), Gaps = 17/1453 (1%)
 Frame = +2

Query: 14   KTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFDEI 193
            KTIEE YQKKTQLEHILLRPDTYIGSIE+HT  LWV+E+ EM +R I YVPGLYKIFDEI
Sbjct: 21   KTIEETYQKKTQLEHILLRPDTYIGSIEQHTQRLWVYENDEMVHRDIKYVPGLYKIFDEI 80

Query: 194  LVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLLTS 373
            LVNAADNKQRDP+MD VKV ID E NLISVYNNGDGVP+E+HQEEGVYVPE+IFGHLLTS
Sbjct: 81   LVNAADNKQRDPSMDSVKVVIDAEQNLISVYNNGDGVPVEVHQEEGVYVPELIFGHLLTS 140

Query: 374  SNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSITK 553
            SNYDD VKKTTGGRNGYGAKLTNIFSTEF+I+TADGKRQKKYKQVFS NMGKKS+P I+K
Sbjct: 141  SNYDDTVKKTTGGRNGYGAKLTNIFSTEFIIETADGKRQKKYKQVFSNNMGKKSEPVISK 200

Query: 554  CKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPVKT 733
            CK  ENWTKV+FKPDLAKFNMTHLE+DVVALMKKRV D+AG LGK VKVELNG RVPVK+
Sbjct: 201  CKEAENWTKVTFKPDLAKFNMTHLEEDVVALMKKRVFDVAGCLGKTVKVELNGKRVPVKS 260

Query: 734  FTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGTHV 913
            F DYV LYL +A+KT+ EPLPR++EK N RWEV VSLS+GQFQQVSFVNGI TIKGGTHV
Sbjct: 261  FLDYVSLYLSAASKTKTEPLPRLLEKVNERWEVGVSLSDGQFQQVSFVNGIATIKGGTHV 320

Query: 914  EYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQGS 1093
            +YVT+QI+                        LWVFVN LIDNPAFDSQTKETLT RQ S
Sbjct: 321  DYVTNQISNYVMNIVNKKNKNANVKAHNVKNHLWVFVNALIDNPAFDSQTKETLTLRQSS 380

Query: 1094 FGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDANDAG 1270
            FGSKCELS +FLKKV K G+V+ LLSWA+FK SK+LKKTDG+K  ++  IPKLDDAN+AG
Sbjct: 381  FGSKCELSEDFLKKVAKCGVVDNLLSWAEFKHSKDLKKTDGAKTGSIRGIPKLDDANEAG 440

Query: 1271 GKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAEIQ 1450
            G+NSDKCTLILTEGDSAKALAVAG++ VGRN YGVFPL+GKLLNVREAS KQ+M NAEIQ
Sbjct: 441  GRNSDKCTLILTEGDSAKALAVAGLAVVGRNHYGVFPLRGKLLNVREASHKQLMDNAEIQ 500

Query: 1451 NIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKGFM 1630
            N+K+ILGLQ GK+Y +VK LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKV  FM
Sbjct: 501  NLKRILGLQQGKEYSNVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFM 560

Query: 1631 VEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGKEYF 1810
            VEFITPIVKA+HK   VLSFY+MPEYE WKESL GNA GW+IKYYKGLGTST+KEGK+YF
Sbjct: 561  VEFITPIVKATHKTKGVLSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYF 620

Query: 1811 KQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSDFVN 1990
            K L KH+K FVW DEQDGE+IELAFSKKKIEARKNWLRQFE GT+LD  ++ IKYS+F+N
Sbjct: 621  KNLDKHRKEFVWQDEQDGEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFIN 680

Query: 1991 KELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHHG 2170
            KELILFS ADLQRSIPSM+DGLKPGQRKILFC+FKRN +KEAKVAQFSGYVSEHSAYHHG
Sbjct: 681  KELILFSMADLQRSIPSMIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHG 740

Query: 2171 EQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFLFPK 2350
            EQSL STIVGMAQDFVGSNNINL  P GQFGTRN+GGKDAAS RYI+T LSPITR+LFPK
Sbjct: 741  EQSLASTIVGMAQDFVGSNNINLLHPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPK 800

Query: 2351 XXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVRRLL 2530
                        GQSIEP WY+PIIPMVLVNGSEGIGTGWSSY+PNYNPRD+VANVRRLL
Sbjct: 801  DDDGLLDYLNEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLL 860

Query: 2531 NDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTADYN 2710
            N E M PM PWYRGFKG IEK+A KE GVTYTI+GIIEEVD TTLRITELP+R WT DY 
Sbjct: 861  NGEQMEPMHPWYRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYR 920

Query: 2711 EFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXXXIS 2890
            EFL++++ G D    PFI++ R Y+DD  V FEVIL+EENMM AKQEG          IS
Sbjct: 921  EFLESIITGND----PFIKEFRQYSDDTTVEFEVILTEENMMMAKQEGLLKKFKLTTTIS 976

Query: 2891 TSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVRFIL 3070
            TSNMHLFDS G IKKYD PEQILE+FFHLR +FYEKRKK+               VRFIL
Sbjct: 977  TSNMHLFDSKGMIKKYDAPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFIL 1036

Query: 3071 AVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXTVKG 3250
             VVKGEIIVNNR+RADLFLEL  KGFTPFPKK K ++ A+AGAT DT         + KG
Sbjct: 1037 GVVKGEIIVNNRKRADLFLELQTKGFTPFPKKAKTVEVAVAGATDDTEETEENSEVSAKG 1096

Query: 3251 VVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALEKQL 3430
             V+ASDY+YLLSM+IGSLTLEKVQELCAD+ KL  E+E+LR  +   LW++DLD LE QL
Sbjct: 1097 -VQASDYDYLLSMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPMSLWLKDLDNLEIQL 1155

Query: 3431 DELDQKDVEAANMQEKIR-RRNTGAAVPSKAPKKPRK-NNAIKGPTVAANDADADVGTTS 3604
            DE D K  +A    + ++ R   G     +APK PRK N   K         D    ++S
Sbjct: 1156 DEQD-KAAQAEEAAKLVKGRGEAGKRAQRQAPKIPRKINKKEKNAETVTETTDI---SSS 1211

Query: 3605 TAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXXKDRLAAYNLDSSPDQT-FM 3781
            +AM+                       +             ++RLA YNLDSSPD +  M
Sbjct: 1212 SAMETETAPAAVKPKGRGGSRKAKKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAM 1271

Query: 3782 ETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISE-DGDDGDFQMVEV 3958
            ETE V Q     K PSKRA   + K   ++S            +I E D +D D ++VEV
Sbjct: 1272 ETE-VPQVPAGKKEPSKRAAAARKKPATSLS--------EISESIGEIDINDEDLEVVEV 1322

Query: 3959 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQ-----GKSLVSQKLITDVLKPVVNA--S 4117
                                           +     GK    QKL+T++LKP  ++  S
Sbjct: 1323 AAAAAPAGKKGGRKPAANSKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGIS 1382

Query: 4118 PEKKVRKMRESPFNKKSGSVLGRARGPVVES-----EGSIDSSPSVNLEVEMNEVPVARN 4282
            PEKKVRKMR SPFNKKSGSVLGR  G  +ES     E    SS S + E E+ E+  AR 
Sbjct: 1383 PEKKVRKMRASPFNKKSGSVLGRV-GKELESTTDSEEAFGSSSMSADTE-EVTEIVPARP 1440

Query: 4283 RPKRENRSKVQYV 4321
            RP+R NR +  YV
Sbjct: 1441 RPQRTNRKQTTYV 1453


>ref|XP_010023678.1| PREDICTED: DNA topoisomerase 2 [Eucalyptus grandis]
 gb|KCW60013.1| hypothetical protein EUGRSUZ_H02748 [Eucalyptus grandis]
          Length = 1496

 Score = 1798 bits (4656), Expect = 0.0
 Identities = 949/1462 (64%), Positives = 1079/1462 (73%), Gaps = 26/1462 (1%)
 Frame = +2

Query: 14   KTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFE-----------DGEMANRPISY 160
            KT+EE YQKK+QLEHILLRPDTYIGS+EKHT  LW+++            GEM +RPI+Y
Sbjct: 29   KTVEETYQKKSQLEHILLRPDTYIGSVEKHTQSLWIYDVGGDGGDGGGGGGEMVHRPITY 88

Query: 161  VPGLYKIFDEILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYV 340
            VPGLYKIFDEILVNAADNKQRDP MD +KV ID + NLISVYNNGDGVP+E+H+EE VYV
Sbjct: 89   VPGLYKIFDEILVNAADNKQRDPRMDSLKVTIDADRNLISVYNNGDGVPVEMHREEHVYV 148

Query: 341  PEMIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSEN 520
            PE+IFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVI+TADGK   KYKQVFS+N
Sbjct: 149  PELIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIETADGKNGLKYKQVFSKN 208

Query: 521  MGKKSDPSITKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKV 700
            MG K  P I  CKA ENWTKVSFKPDLAKFNMTHLEDDVVALMKKRV+D+AG LGK VKV
Sbjct: 209  MGVKGAPDIKACKASENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVIDMAGCLGKTVKV 268

Query: 701  ELNGTRVPVKTFTDYVDLYLKSANKTRDE-PLPRIIEKANNRWEVCVSLSEGQFQQVSFV 877
            ELNG RVPVKTF +YV LYLKSA+K R E PLPRI E  N+RWEVCVSLS+GQFQQVSF 
Sbjct: 269  ELNGKRVPVKTFAEYVGLYLKSASKNRPECPLPRIEETVNDRWEVCVSLSDGQFQQVSFA 328

Query: 878  NGINTIKGGTHVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDS 1057
            N I TIKGGTHV+YVT+QI                         LWVFVN LIDNPAFDS
Sbjct: 329  NAIATIKGGTHVDYVTNQIANHVMSVVNKKNKNANLKAHNVKSHLWVFVNALIDNPAFDS 388

Query: 1058 QTKETLTTRQGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN 1237
            QTKETLT RQ SFGSKCELS +FL+KV KSGIVE+LLSWA+FK SK+LKKTDGSKR+N+ 
Sbjct: 389  QTKETLTLRQSSFGSKCELSDKFLQKVVKSGIVESLLSWANFKLSKDLKKTDGSKRENLR 448

Query: 1238 -IPKLDDANDAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREA 1414
             IPKL+DANDAGG+NSDKCTLILTEGDSAKALA+AG+S VGR+ YGVFPL+GKLLNVREA
Sbjct: 449  GIPKLEDANDAGGRNSDKCTLILTEGDSAKALAMAGLSVVGRDRYGVFPLRGKLLNVREA 508

Query: 1415 SLKQIMQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHS 1594
            S  QIM+N EIQ IKQILGLQ  K YDSVK LRYG LMIMTDQDHDGSHIKGLLINF+HS
Sbjct: 509  SHSQIMENKEIQYIKQILGLQQNKDYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFVHS 568

Query: 1595 FWPSLLKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGL 1774
            FWPSLLKV  F+VEFITPIVKA+HKNG  LSFYTMPEYE+WKESL G+ +GW+IKYYKGL
Sbjct: 569  FWPSLLKVPSFLVEFITPIVKATHKNGRELSFYTMPEYESWKESLGGSGSGWSIKYYKGL 628

Query: 1775 GTSTAKEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDH 1954
            GTST+KEGK+YF+ L  HKK FVW D+QDG++IELAFSKKKIEARK WLRQFE GTYLD 
Sbjct: 629  GTSTSKEGKQYFQNLDMHKKDFVWVDDQDGDAIELAFSKKKIEARKTWLRQFEPGTYLDQ 688

Query: 1955 KEEEIKYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFS 2134
            KE+ IKYSDFVNKELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN IKEAKVAQFS
Sbjct: 689  KEKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFS 748

Query: 2135 GYVSEHSAYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYT 2314
            GYVSEHSAYHHGEQSL STI+GMAQD+VGSNNINL  PNGQFGTRN GGKD AS RY+YT
Sbjct: 749  GYVSEHSAYHHGEQSLASTIIGMAQDYVGSNNINLLMPNGQFGTRNMGGKDHASPRYVYT 808

Query: 2315 CLSPITRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYN 2494
             LSP TRFLFPK            GQSIEP WYMPI+PMVLVNGSEGIGTGWSSY+PNYN
Sbjct: 809  KLSPTTRFLFPKDDDNLLSYLNEDGQSIEPTWYMPILPMVLVNGSEGIGTGWSSYIPNYN 868

Query: 2495 PRDVVANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRIT 2674
            PRD++AN+RRLLN E M PM+PWYRGF+G IEK+A KE GVTYT+ GIIEEVD TTLRIT
Sbjct: 869  PRDIIANLRRLLNGEMMEPMDPWYRGFRGTIEKTATKEAGVTYTVCGIIEEVDDTTLRIT 928

Query: 2675 ELPIRSWTADYNEFLDAMMKGT-DKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQE 2851
            ELPIR WT DY EFL+++  G  DK K+PF+++ R Y+DDV VHFEV+L+EENMM AKQE
Sbjct: 929  ELPIRRWTQDYREFLESLSTGEKDKAKDPFVKEFRQYSDDVTVHFEVMLTEENMMIAKQE 988

Query: 2852 GXXXXXXXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXX 3031
            G          ISTSNMHLFD NG IKKYD+PEQILE+FFHLRL+ YEKRKK+       
Sbjct: 989  GLLKKFKLTSSISTSNMHLFDPNGVIKKYDSPEQILEEFFHLRLECYEKRKKILLENLEL 1048

Query: 3032 XXXXXXXXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDT 3211
                    VRFIL VV GEIIV+NR+RADLF EL  KGFTPF K+TK I+ A+AG+T D 
Sbjct: 1049 KLVMLDNKVRFILGVVHGEIIVSNRKRADLFQELQAKGFTPFRKETKTIETAVAGSTDDA 1108

Query: 3212 XXXXXXXXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKI 3391
                     T KGV KASDYEYLLSM+IG+LTLEKVQELCADK KL  E++ LR  + + 
Sbjct: 1109 EETEENSEPTTKGV-KASDYEYLLSMAIGALTLEKVQELCADKDKLVDEVDALRKATPEN 1167

Query: 3392 LWMRDLDALEKQLDELDQKDVEAANMQEKIRRRN-TGAAVPSKAPKKPRKNNAIKGPTVA 3568
            LW+ DL ALE++LDE ++ D +A   ++   + N  G  V  +APKKPRKN+     T A
Sbjct: 1168 LWLEDLAALEEKLDEQEKMDAQAEETRKARSKANGVGTKVSRQAPKKPRKND-----TKA 1222

Query: 3569 AN-DADADVGTTSTA-MDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXX----- 3727
             N +A A+V   ST  ++AGN                 A K +                 
Sbjct: 1223 NNPEAQAEVTQGSTVTLEAGNAADVAKPKRGAGARKAPAPKPSKSASVSDDDEDFEMLDL 1282

Query: 3728 KDRLAAYNLDSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXX 3907
            K+RLAAYNL+SSPD +    + V +  +K K PSKRA  RK  S +              
Sbjct: 1283 KERLAAYNLESSPDNSSALEDKVPEIPVKEKEPSKRAATRKKPSVILSEISEEEN----- 1337

Query: 3908 PAISEDGDDGDFQMV--EVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKL 4081
               S D  D D++ V  E                                Q     SQ+L
Sbjct: 1338 ---SNDSGDDDYETVDSEAEVAKKKGGRKPSAAAKKSKPPAATKKGQANRQQARGTSQRL 1394

Query: 4082 ITDVLKPV--VNASPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVE 4255
            +T++LKP      SPEKKVRKMR SPFNKKS S+LG+       +   + S+P  N   +
Sbjct: 1395 LTEMLKPAESTGVSPEKKVRKMRASPFNKKSSSLLGKEGKADSSTSEEMSSNPMSNDGED 1454

Query: 4256 MNEVPVARNRPKRENRSKVQYV 4321
            + EV   + RP+R NR +  YV
Sbjct: 1455 VVEVAPPKRRPQRVNRKQTTYV 1476


>ref|XP_015881654.1| PREDICTED: DNA topoisomerase 2 isoform X2 [Ziziphus jujuba]
          Length = 1486

 Score = 1780 bits (4611), Expect = 0.0
 Identities = 926/1458 (63%), Positives = 1087/1458 (74%), Gaps = 18/1458 (1%)
 Frame = +2

Query: 2    GGGK---KTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGL 172
            GGG    KTIEE+YQKK+QLEHILLRPDTYIGSIEKHT  LWV+++ EM +R ++YVPGL
Sbjct: 26   GGGNGPAKTIEEMYQKKSQLEHILLRPDTYIGSIEKHTQTLWVYQNDEMVHRSVTYVPGL 85

Query: 173  YKIFDEILVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMI 352
            YKIFDEILVNAADNKQRDP+MD +KV ID E N ISVYNNGDGVP+EIHQEE VYVPE+I
Sbjct: 86   YKIFDEILVNAADNKQRDPSMDSLKVIIDVEQNCISVYNNGDGVPVEIHQEEKVYVPELI 145

Query: 353  FGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKK 532
            FGHLLTSSNYDD VKKTTGGRNGYGAKLTNIFSTEF+I+TADGKRQKKYKQVFS+NMGKK
Sbjct: 146  FGHLLTSSNYDDTVKKTTGGRNGYGAKLTNIFSTEFLIETADGKRQKKYKQVFSDNMGKK 205

Query: 533  SDPSITKCKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNG 712
            S+P ITKCK GENWTKV+FKPDL KFNMTHLEDDVVALMKKRV+D+AG LGK VKVELNG
Sbjct: 206  SEPVITKCKEGENWTKVTFKPDLGKFNMTHLEDDVVALMKKRVIDMAGCLGKTVKVELNG 265

Query: 713  TRVPVKTFTDYVDLYLKSANKTRDEPLPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINT 892
             RVPVKTF DYVDLYL+SA K+RD  LPRI E+ N+RWE+CVSLS+GQFQQVSFVN I T
Sbjct: 266  RRVPVKTFLDYVDLYLQSARKSRDVTLPRITERVNDRWEICVSLSDGQFQQVSFVNSIAT 325

Query: 893  IKGGTHVEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKET 1072
            IKGGTHV+Y+T+QIT                        LWVFV+ LIDNPAFDSQTKET
Sbjct: 326  IKGGTHVDYITNQITNHVMNVVNKKNKNANVKAHNVKNYLWVFVSALIDNPAFDSQTKET 385

Query: 1073 LTTRQGSFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNV-NIPKL 1249
            LT R  SFGSKCEL  EFLKKV KSGIV++LLSWA+FK +K+LKKTDG+K + V NI KL
Sbjct: 386  LTIRPSSFGSKCELPPEFLKKVAKSGIVDSLLSWANFKNNKDLKKTDGTKTERVHNINKL 445

Query: 1250 DDANDAGGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQI 1429
            +DAN+AGG+NSDKCTLILTEGDSAKALA+AG+S VGR+ YGVFPL+GKLLNVREAS  Q+
Sbjct: 446  EDANEAGGRNSDKCTLILTEGDSAKALAMAGLSVVGRDRYGVFPLRGKLLNVREASSNQV 505

Query: 1430 MQNAEIQNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSL 1609
              N EI+NIK+ILGLQ  K+Y +VK LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSL
Sbjct: 506  RDNEEIKNIKRILGLQQDKEYTNVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSL 565

Query: 1610 LKVKGFMVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTA 1789
            LKV  F+VEFITPIVKA+HKNG  L+FYTMP+YE+W+ESL GNA+GW+IKYYKGLGTST+
Sbjct: 566  LKVPSFLVEFITPIVKATHKNGKELAFYTMPQYESWRESLRGNASGWSIKYYKGLGTSTS 625

Query: 1790 KEGKEYFKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEI 1969
            KEG+EYF+ L KH+K F+W D+QDG +IELAFSKKKIE RKNWLRQFE GT+LD KE+ I
Sbjct: 626  KEGREYFQNLDKHRKDFLWVDDQDGAAIELAFSKKKIEERKNWLRQFEPGTHLDQKEKLI 685

Query: 1970 KYSDFVNKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSE 2149
            KYSDFV+KELILFS ADLQRSIPSMVDGLKPGQRKILFC+FKRN  KEAKVAQFSGYVSE
Sbjct: 686  KYSDFVHKELILFSVADLQRSIPSMVDGLKPGQRKILFCSFKRNFFKEAKVAQFSGYVSE 745

Query: 2150 HSAYHHGEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPI 2329
            HSAYHHGEQSL STI+GMAQD+VGSNNINL QPNGQFGTRN GGKD AS RYI+T LSPI
Sbjct: 746  HSAYHHGEQSLASTIIGMAQDYVGSNNINLLQPNGQFGTRNLGGKDHASARYIFTRLSPI 805

Query: 2330 TRFLFPKXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVV 2509
            TRFLFPK            GQ+IEP WY+PIIP VLVNGSEGIGTGWSSY+PNYNPRD+V
Sbjct: 806  TRFLFPKDDDKLLDYLNEDGQTIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIV 865

Query: 2510 ANVRRLLNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIR 2689
            AN+RRLLN   M PM+PWYRGFKG IEK+  KE GV+YTISGI+EEV+ TT+RITELPIR
Sbjct: 866  ANIRRLLNGHSMVPMDPWYRGFKGTIEKTV-KEAGVSYTISGILEEVNETTIRITELPIR 924

Query: 2690 SWTADYNEFLDAMMKGTDKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXX 2869
             WT DY EFL+++ +G DK K+PFI+    ++D + V   V + EEN++AAKQEG     
Sbjct: 925  KWTQDYKEFLESISQGNDKAKDPFIEGFTQHSDHITVDILVHMPEENLVAAKQEGLLKKF 984

Query: 2870 XXXXXISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXX 3049
                 ISTSNMHLFD+ G IKKYDTPEQILE+FFHLRL+FYEKRK+V             
Sbjct: 985  KLTTTISTSNMHLFDAKGVIKKYDTPEQILEEFFHLRLEFYEKRKQVLLDNLEMELLKLE 1044

Query: 3050 XXVRFILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXX 3229
              VRFIL VV  EIIV+NR+RADLFLEL QKGFTPFPKK K ++  +AGAT  T      
Sbjct: 1045 NKVRFILGVVNEEIIVSNRKRADLFLELQQKGFTPFPKKAKSVEPEVAGATDYTEETEDN 1104

Query: 3230 XXXTVKGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDL 3409
                    V+ SDYEYLLSM+IG+LTLEKVQ LCA++ KL+ E+++LR  + K LW +DL
Sbjct: 1105 SNPDG---VRISDYEYLLSMAIGTLTLEKVQALCAERDKLNGEVDDLRKATPKSLWEKDL 1161

Query: 3410 DALEKQLDELDQKDVEAANMQEKIRRRNTGAAVP--SKAPKKPRKNNAIKGPTVAANDAD 3583
            DAL+K+LDELD+ D +A + ++K++ +   AAV   +KAPK PRKNN       A  +  
Sbjct: 1162 DALDKELDELDKNDAQAEDARKKLKSQLNPAAVTKFAKAPKNPRKNNKKANNAEAVVEMM 1221

Query: 3584 ADVGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXX---KDRLAAYNL 3754
                +++  M+                     +K  V+             K+RLAAYNL
Sbjct: 1222 ETTSSSTMEMEKAPEVVKPKGRAVSRKAPTKKEKPAVILDDDDDDDEVLELKERLAAYNL 1281

Query: 3755 DSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGD- 3931
            +SSPD+         Q  ++ K P+KRA  +K K+++ ++             IS+D D 
Sbjct: 1282 ESSPDRPADMESEAPQVPVQKKEPTKRAAAQK-KASVNLT------------TISDDEDE 1328

Query: 3932 --DGDFQMVEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVSQKLITDVLKPV 4105
              D DF++                                  +    + Q+L+T++LKP 
Sbjct: 1329 SFDEDFELETEAAAKKKGGRKAAANTKASKPNAAAAKRGAANKQPRTLGQRLVTEMLKPA 1388

Query: 4106 VNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSS----PSVNLEVEMNEV 4267
              +  SPEKKVRKMR SPFNKKS S+LGR      E+ GS D S    P+ +   E  EV
Sbjct: 1389 ETSGISPEKKVRKMRASPFNKKSSSMLGRVANEDDEATGSEDMSVSPPPTFDDTEEGMEV 1448

Query: 4268 PVARNRPKRENRSKVQYV 4321
            P  R RP+R NR++ +YV
Sbjct: 1449 PATRARPQRANRTQARYV 1466


>gb|OWM78385.1| hypothetical protein CDL15_Pgr016109 [Punica granatum]
 gb|PKI31894.1| hypothetical protein CRG98_047704 [Punica granatum]
          Length = 1473

 Score = 1776 bits (4599), Expect = 0.0
 Identities = 949/1455 (65%), Positives = 1078/1455 (74%), Gaps = 19/1455 (1%)
 Frame = +2

Query: 14   KTIEEVYQKKTQLEHILLRPDTYIGSIEKHTAVLWVFEDGEMANRPISYVPGLYKIFDEI 193
            KTIEE YQKK+QLEHILLRPDTYIGSIEKHT  +WV+E+ EM +RP++YVPGLYKIFDEI
Sbjct: 27   KTIEETYQKKSQLEHILLRPDTYIGSIEKHTQTMWVYENEEMVHRPVTYVPGLYKIFDEI 86

Query: 194  LVNAADNKQRDPTMDCVKVDIDPESNLISVYNNGDGVPIEIHQEEGVYVPEMIFGHLLTS 373
            LVNAADNKQRDP MD VKV ID E NLISVYNNGDGVP+EIHQEE VYVPE+IFGHLLTS
Sbjct: 87   LVNAADNKQRDPRMDSVKVTIDVEHNLISVYNNGDGVPVEIHQEEQVYVPELIFGHLLTS 146

Query: 374  SNYDDNVKKTTGGRNGYGAKLTNIFSTEFVIQTADGKRQKKYKQVFSENMGKKSDPSITK 553
            SNYDD+VKKTTGGRNGYGAKLTNIFSTEFVI+TADGKRQ+KYKQVFS NMGK+++P+I K
Sbjct: 147  SNYDDSVKKTTGGRNGYGAKLTNIFSTEFVIETADGKRQRKYKQVFSNNMGKRNEPTIVK 206

Query: 554  CKAGENWTKVSFKPDLAKFNMTHLEDDVVALMKKRVVDLAGTLGKGVKVELNGTRVPVKT 733
            CK G+NWTKVSFKPDL+KFNMTHLEDDVVALMKKRVVDLAG LGK VKVELNG RVPVKT
Sbjct: 207  CKEGDNWTKVSFKPDLSKFNMTHLEDDVVALMKKRVVDLAGCLGKTVKVELNGKRVPVKT 266

Query: 734  FTDYVDLYLKSANKTRDEP-LPRIIEKANNRWEVCVSLSEGQFQQVSFVNGINTIKGGTH 910
            F +YV LYL SA+K R E  LPRI E  N+RWEVCVSLSEGQFQQVSFVN I TIKGGTH
Sbjct: 267  FGEYVGLYLASASKNRPESSLPRIEEAVNDRWEVCVSLSEGQFQQVSFVNSIATIKGGTH 326

Query: 911  VEYVTSQITXXXXXXXXXXXXXXXXXXXXXXXXLWVFVNTLIDNPAFDSQTKETLTTRQG 1090
            V+YVT+QI                         LWVFVN LIDNPAFDSQTKETLT RQ 
Sbjct: 327  VDYVTNQIANHVMSVVNKKNKNANLKAHNVKNHLWVFVNALIDNPAFDSQTKETLTLRQS 386

Query: 1091 SFGSKCELSGEFLKKVDKSGIVETLLSWADFKQSKELKKTDGSKRQNVN-IPKLDDANDA 1267
            SFGSKCELS +FL+KV KSGIVETLLSWA FK SK+LKKTDGSK++N+  IPKL+DANDA
Sbjct: 387  SFGSKCELSDKFLQKVAKSGIVETLLSWATFKLSKDLKKTDGSKKENLRGIPKLEDANDA 446

Query: 1268 GGKNSDKCTLILTEGDSAKALAVAGVSEVGRNLYGVFPLKGKLLNVREASLKQIMQNAEI 1447
            GG+NSDKCTLILTEGDSAKALA+AG+S VGR+ YGVFPL+GKLLNVREAS  QIM N EI
Sbjct: 447  GGRNSDKCTLILTEGDSAKALAMAGLSVVGRDHYGVFPLRGKLLNVREASHSQIMDNKEI 506

Query: 1448 QNIKQILGLQHGKQYDSVKGLRYGSLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVKGF 1627
            Q+IKQILGLQ  K YDSVK LRYG LMIMTDQDHDGSHIKGLLINFIHSFWPSLLKV  F
Sbjct: 507  QHIKQILGLQQNKDYDSVKSLRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSF 566

Query: 1628 MVEFITPIVKASHKNGTVLSFYTMPEYEAWKESLNGNATGWTIKYYKGLGTSTAKEGKEY 1807
            MVEFITPIVKA+HKNG  L FYTMPEYE+WKESL+GNA+GW+IKYYKGLGTST+KEGK+Y
Sbjct: 567  MVEFITPIVKATHKNGRELCFYTMPEYESWKESLSGNASGWSIKYYKGLGTSTSKEGKQY 626

Query: 1808 FKQLRKHKKSFVWADEQDGESIELAFSKKKIEARKNWLRQFEAGTYLDHKEEEIKYSDFV 1987
            F+ L KHKK F+WADE+DGE+IELAFSKKKIEARKNWLRQFE GT+LD KE+ IKYSDFV
Sbjct: 627  FQALNKHKKDFIWADEKDGEAIELAFSKKKIEARKNWLRQFEPGTFLDQKEKLIKYSDFV 686

Query: 1988 NKELILFSRADLQRSIPSMVDGLKPGQRKILFCAFKRNLIKEAKVAQFSGYVSEHSAYHH 2167
            NKELILFS ADLQRSIPSM+DGLKPGQRKILFC+FKRN +KEAKVAQFSGYVSEHSAYHH
Sbjct: 687  NKELILFSMADLQRSIPSMLDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHH 746

Query: 2168 GEQSLVSTIVGMAQDFVGSNNINLFQPNGQFGTRNKGGKDAASGRYIYTCLSPITRFLFP 2347
            GEQSL  TI+GMAQDFVGSNNINL  P+GQFGTRN GGKD AS RYIYT LSPITRFLFP
Sbjct: 747  GEQSLAGTIIGMAQDFVGSNNINLLVPSGQFGTRNMGGKDHASPRYIYTRLSPITRFLFP 806

Query: 2348 KXXXXXXXXXXXXGQSIEPAWYMPIIPMVLVNGSEGIGTGWSSYVPNYNPRDVVANVRRL 2527
            K            G SIEP W++PIIP VLVNGSEGIGTGWSSY+PNYNPRD++ NVRRL
Sbjct: 807  KDDDNLLDYLNEDGVSIEPTWFVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIINNVRRL 866

Query: 2528 LNDEPMRPMEPWYRGFKGLIEKSAQKETGVTYTISGIIEEVDITTLRITELPIRSWTADY 2707
            LN E M PM+PWYRGFKG IEK+A KE G +YT+ GI+EE++ TTLRITELPIR WT DY
Sbjct: 867  LNGEMMEPMDPWYRGFKGTIEKTATKEAGDSYTVHGIMEEINETTLRITELPIRRWTQDY 926

Query: 2708 NEFLDAMMKGT-DKFKEPFIQDKRAYNDDVIVHFEVILSEENMMAAKQEGXXXXXXXXXX 2884
             EFL++++ G  DK KEPFI++ + Y+DD+ VHFEV LSEENM+ AKQEG          
Sbjct: 927  REFLESLVVGDKDKNKEPFIKEFKQYSDDISVHFEVALSEENMIIAKQEGLMKKFKLTST 986

Query: 2885 ISTSNMHLFDSNGTIKKYDTPEQILEDFFHLRLQFYEKRKKVXXXXXXXXXXXXXXXVRF 3064
            ISTSNMHLFD+ G IKKYDTPEQILE+FF LRL FYEKRKK                VRF
Sbjct: 987  ISTSNMHLFDAKGIIKKYDTPEQILEEFFPLRLGFYEKRKKFLLDNLEMELLKLDNKVRF 1046

Query: 3065 ILAVVKGEIIVNNRRRADLFLELHQKGFTPFPKKTKGIDAAIAGATVDTXXXXXXXXXTV 3244
            IL VV GEIIVNNR+RA+LF+EL +KGFTPFPKKTK I+AAIAGA+ D+         T 
Sbjct: 1047 ILGVVNGEIIVNNRKRAELFIELQEKGFTPFPKKTKSIEAAIAGASEDSEETEDNSESTG 1106

Query: 3245 KGVVKASDYEYLLSMSIGSLTLEKVQELCADKQKLDHELEELRSTSSKILWMRDLDALEK 3424
               VKASDYEYLLSM+IGSLT EKVQELCA++ KL  E+E L+S++   LW++DL+ LE+
Sbjct: 1107 SKEVKASDYEYLLSMAIGSLTREKVQELCAERDKLLDEVEGLKSSTPMDLWLKDLEDLER 1166

Query: 3425 QLDELDQKDVEAANMQEKIRRRNTGAAVPS---KAPKKPRKNN--AIKGPTVAANDADAD 3589
            +LDELD+ D EA   ++  + R T AA      +APK PRKN   A     V  N     
Sbjct: 1167 ELDELDKNDAEADAARKVSQARATSAAGAKGSRQAPKNPRKNTKKATNLEAVGENSEMPS 1226

Query: 3590 VGTTSTAMDAGNXXXXXXXXXXXXXXXDAAKKTTVVXXXXXXXXXX-----KDRLAAYNL 3754
              ++S   D                   A K+                   K+RLA YNL
Sbjct: 1227 TNSSSVVTDNAAPVAKPKGRGGAKKAPAATKQNRSAAVLEDEDDDEELLDLKERLARYNL 1286

Query: 3755 DSSPDQTFMETESVAQEVLKMKAPSKRATVRKGKSTMTISXXXXXXXXXXXPAISEDGDD 3934
            DSSP+ +        Q     K P+KRA   K K+ +T+             +  E G D
Sbjct: 1287 DSSPENSAATENEGPQVPATKKEPTKRAAAAK-KTVITL----------LESSDEESGKD 1335

Query: 3935 --GDFQM-VEVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQGKSLVS-QKLITDVLKP 4102
              GD  + +EV                                 K++ + QKL+TD+LKP
Sbjct: 1336 KAGDEDLDIEV---------EPPKGKKGGKKPSAAATRKRGPANKTIAAGQKLLTDMLKP 1386

Query: 4103 VVNA--SPEKKVRKMRESPFNKKSGSVLGRARGPVVESEGSIDSSPSVNLEVEMNEVPVA 4276
              N+  SPEKKVR+MR SPFN+KS         P + SE S+ S    N   E   V  +
Sbjct: 1387 SENSDISPEKKVRRMRASPFNRKSSI-------PTI-SEESLGS----NERDEEAPVLPS 1434

Query: 4277 RNRPKRENRSKVQYV 4321
            R RP+R NR + +YV
Sbjct: 1435 RARPQRANRQQKKYV 1449