BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Ophiopogon22_contig00010616
         (2522 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_009403000.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1279   0.0  
ref|XP_020104572.1| DNA topoisomerase 3-alpha [Ananas comosus]       1278   0.0  
ref|XP_008807898.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1267   0.0  
gb|AIC82458.1| topoisomerase 3alpha [Cocos nucifera]                 1257   0.0  
ref|XP_008807899.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1256   0.0  
ref|XP_010907414.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1255   0.0  
gb|PKU87668.1| DNA topoisomerase III [Dendrobium catenatum]          1229   0.0  
ref|XP_020673261.1| DNA topoisomerase 3-alpha isoform X5 [Dendro...  1229   0.0  
ref|XP_010649354.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1222   0.0  
ref|XP_020259033.1| DNA topoisomerase 3-alpha [Asparagus officin...  1221   0.0  
ref|XP_010649353.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1218   0.0  
ref|XP_020673257.1| DNA topoisomerase 3-alpha isoform X1 [Dendro...  1215   0.0  
ref|XP_020673258.1| DNA topoisomerase 3-alpha isoform X2 [Dendro...  1215   0.0  
gb|OVA03617.1| DNA topoisomerase [Macleaya cordata]                  1215   0.0  
ref|XP_010270299.1| PREDICTED: DNA topoisomerase 3-alpha [Nelumb...  1213   0.0  
ref|XP_004502963.1| PREDICTED: DNA topoisomerase 3-alpha [Cicer ...  1205   0.0  
ref|XP_019702432.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1201   0.0  
ref|XP_012489371.1| PREDICTED: DNA topoisomerase 3-alpha isoform...  1200   0.0  
ref|XP_017629354.1| PREDICTED: DNA topoisomerase 3-alpha [Gossyp...  1198   0.0  
ref|XP_024184593.1| DNA topoisomerase 3-alpha isoform X1 [Rosa c...  1197   0.0  

>ref|XP_009403000.1| PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Musa acuminata
            subsp. malaccensis]
          Length = 920

 Score = 1279 bits (3309), Expect = 0.0
 Identities = 614/838 (73%), Positives = 692/838 (82%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK +S IL               YNR+FEFEYT+ SQ CHM+ TSV GHLME
Sbjct: 15   NVAEKPSVAKAVSEILSRGSGGMRSRLGRSRYNRVFEFEYTIGSQACHMLVTSVIGHLME 74

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+FE+R+RKWHSCDPAELY AP++K VPQDKLDI+ TLEEEAR+CQWLVLWLD D EGEN
Sbjct: 75   LEFEDRFRKWHSCDPAELYHAPVRKHVPQDKLDIKITLEEEARRCQWLVLWLDCDREGEN 134

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEVIEVCT+VN H+ IWRA FS++ +R+I+ SVQ+L +PNKL +D+VDARQEIDLRIG
Sbjct: 135  IAFEVIEVCTSVNDHLNIWRAHFSALIDREIHHSVQNLARPNKLFSDAVDARQEIDLRIG 194

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLLKD FVLDFA D+RS+VLSYGPCQFPTLGF+VERYWEIQSHE EEFW I 
Sbjct: 195  ASFTRFQTMLLKDLFVLDFASDNRSLVLSYGPCQFPTLGFIVERYWEIQSHEAEEFWTIN 254

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH S+EGTA F W R  L+D++ A +IYEMCVEEP ATVKNV H+E+LKYPPYPLST+E
Sbjct: 255  CSHTSEEGTANFIWMRGHLFDYTSAVVIYEMCVEEPAATVKNVKHQEKLKYPPYPLSTVE 314

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            LQKRASR  RMSS+HTMK+AEELY +GFISYPRTETD FS N DL  IVREQ+ HP WGS
Sbjct: 315  LQKRASRFFRMSSEHTMKIAEELYQAGFISYPRTETDGFSVNTDLHAIVREQVTHPIWGS 374

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQQLLD E RLWRNP NGGHDDKAHPPIHPTKFSAGE+GWS+DHNRLYELVVRHFLACV
Sbjct: 375  YAQQLLDVEARLWRNPSNGGHDDKAHPPIHPTKFSAGETGWSQDHNRLYELVVRHFLACV 434

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA TTV+IDIAGEQFSASG VII +NYLDVY ++SW G+I+PTY IGQQF+PT+L
Sbjct: 435  SQPAVGAETTVEIDIAGEQFSASGRVIIAKNYLDVYRFESWGGNIVPTYTIGQQFIPTSL 494

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR YATKDS ++FSPTNLG
Sbjct: 495  TLDSGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRCYATKDSNTRFSPTNLG 554

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYD+MGYELWKPYLRA ME DMK VS GTKRKS+ L SCLQ++K  FLDARR KV
Sbjct: 555  EALVMGYDEMGYELWKPYLRAMMECDMKAVSIGTKRKSEVLESCLQQMKACFLDARRNKV 614

Query: 1801 NLLEAMELFFERSNRPVGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCRN 1980
             LLEAM LFFERS    GD  N GE VRPC+ C E+ MVLKRRLNGD+M GCL FP+CRN
Sbjct: 615  KLLEAMGLFFERS---AGDAHNVGETVRPCSLCSEADMVLKRRLNGDYMVGCLRFPNCRN 671

Query: 1981 VVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKDL 2160
            VVWLPG+ISEA+VT +VCSSCAPGPV+K+Q KFRRLEIPPNYDVDHLGCIGGCD IL++L
Sbjct: 672  VVWLPGSISEAAVTNHVCSSCAPGPVYKVQFKFRRLEIPPNYDVDHLGCIGGCDVILREL 731

Query: 2161 IEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXXX 2340
            IEICGTGS   TGM+ARGQR  E  +   R N RQ+ C HC QTGHSSN CPSQ      
Sbjct: 732  IEICGTGSHNHTGMSARGQRGTEPMSSASRGNSRQEPCLHCGQTGHSSNHCPSQDSSCPR 791

Query: 2341 XXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                          G++ C SCGA+C +RTA TE NRGRKFY+CQ++ECGFFVW D L
Sbjct: 792  AAQPARVRNARIISGEVQCNSCGATCALRTANTESNRGRKFYTCQSQECGFFVWADSL 849


>ref|XP_020104572.1| DNA topoisomerase 3-alpha [Ananas comosus]
          Length = 922

 Score = 1278 bits (3308), Expect = 0.0
 Identities = 607/841 (72%), Positives = 699/841 (83%), Gaps = 3/841 (0%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXX---YNRIFEFEYTLRSQPCHMIFTSVTGH 171
            NVAEKPSVAK +S IL                  YNR+FEFEY++  +PC M+FTSVTGH
Sbjct: 12   NVAEKPSVAKAVSEILSRGGGGGGGLRSREGRSRYNRVFEFEYSIGGRPCLMLFTSVTGH 71

Query: 172  LMELDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSE 351
            LMELDF++R+RKW+SCDP +LY APL+K VPQDKLDI++TLEEEARKCQWLVLWLD D E
Sbjct: 72   LMELDFDDRFRKWNSCDPTDLYHAPLRKLVPQDKLDIKKTLEEEARKCQWLVLWLDCDRE 131

Query: 352  GENIAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDL 531
            GENIAFEV+EVCTA NRH+ IWRA FS++T+RDI  SV +L +PNKL AD+VDARQEIDL
Sbjct: 132  GENIAFEVVEVCTAANRHLDIWRAHFSALTDRDIRESVANLGRPNKLFADAVDARQEIDL 191

Query: 532  RIGASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFW 711
            RIGASFTRFQTMLL+DAFVLDFAGD+R++VLSYGPCQFPTLGF+VERYWEIQSHEPEEFW
Sbjct: 192  RIGASFTRFQTMLLRDAFVLDFAGDERNLVLSYGPCQFPTLGFIVERYWEIQSHEPEEFW 251

Query: 712  KITCSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLS 891
             I CSH S+EGTA F W R  L+D++CA +IYEMCVEEPTATVKNV H E+LKYPPYPLS
Sbjct: 252  TINCSHTSEEGTANFSWMRGHLFDYNCAVVIYEMCVEEPTATVKNVKHHEKLKYPPYPLS 311

Query: 892  TLELQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPT 1071
            T+ELQKRASR  RMSS+HTMKVAEELY +GFISYPRTETD FS N DL GIVR+Q+GH  
Sbjct: 312  TVELQKRASRYFRMSSEHTMKVAEELYQAGFISYPRTETDGFSVNTDLHGIVRDQVGHHV 371

Query: 1072 WGSYAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFL 1251
            WGSYAQ+LL  E  LWRNP NGGHDDKAHPPIHPTKFSAGE GWS+DHN+LYELVVRHFL
Sbjct: 372  WGSYAQRLLHSEAGLWRNPSNGGHDDKAHPPIHPTKFSAGEPGWSQDHNKLYELVVRHFL 431

Query: 1252 ACVSQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLP 1431
            ACVSQPAVGA TTV+ID+AGEQF+ASG VII +NYLDVY ++SW G+++PTY +GQQF+P
Sbjct: 432  ACVSQPAVGAETTVEIDVAGEQFNASGRVIIAKNYLDVYRFESWGGTLLPTYTVGQQFIP 491

Query: 1432 TTLKLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPT 1611
            T+L L+SGVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR YATKDS ++FSPT
Sbjct: 492  TSLTLDSGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRCYATKDSNTRFSPT 551

Query: 1612 NLGEALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARR 1791
            NLGEALVMGYD+MGYELWKPYLR+ ME DMK VS GTKRKS+ L +CLQ++K  FLDAR 
Sbjct: 552  NLGEALVMGYDEMGYELWKPYLRSMMECDMKAVSMGTKRKSEVLENCLQQMKACFLDARV 611

Query: 1792 QKVNLLEAMELFFERSNRPVGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPH 1971
             KV LLEAME+FFERSNRP GD  N  EVVRPC  C+ES+MVLKRR NG+FM GCL+FP 
Sbjct: 612  NKVKLLEAMEIFFERSNRPSGDANNFREVVRPCGICNESNMVLKRRPNGEFMVGCLHFPL 671

Query: 1972 CRNVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSIL 2151
            CRNVVWLPG++SEA+VT+NVC +CAPGPV+ IQ KFRR+EIPPNYDVDHLGCIGGCDS L
Sbjct: 672  CRNVVWLPGSLSEAAVTSNVCPTCAPGPVYMIQFKFRRVEIPPNYDVDHLGCIGGCDSTL 731

Query: 2152 KDLIEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFX 2331
            ++L EICGTGSR  +  TARGQR  ETP+  RR N RQ++C +CRQ GHSSN+CPSQ   
Sbjct: 732  RELTEICGTGSRNQSNATARGQRTTETPSSVRRGNSRQESCTYCRQPGHSSNDCPSQ-VS 790

Query: 2332 XXXXXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDD 2511
                          N  GQ+ C SCG  C +RTA TE NRGR+FY+CQ++EC FFVWED+
Sbjct: 791  RSRGFQSTRAQNSRNTSGQVLCSSCGEPCALRTANTESNRGRRFYTCQSQECSFFVWEDN 850

Query: 2512 L 2514
            L
Sbjct: 851  L 851


>ref|XP_008807898.1| PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Phoenix dactylifera]
          Length = 920

 Score = 1267 bits (3279), Expect = 0.0
 Identities = 606/838 (72%), Positives = 693/838 (82%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++ IL               YNR+FEFEY +  Q CHM+ TSVTGHLME
Sbjct: 14   NVAEKPSVAKAVAEILSRRGGGFRSREGRSRYNRVFEFEYAIGPQLCHMLVTSVTGHLME 73

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+F++R+RKWHSCDPA+LY A ++K VPQDKLDI+RTLEEEAR CQWLVLWLD D EGEN
Sbjct: 74   LEFDDRFRKWHSCDPADLYHAAVRKHVPQDKLDIKRTLEEEARSCQWLVLWLDCDREGEN 133

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV+EVCT++N  + +WRA FS++ +R+I+ +VQ+L +PNKL AD+VD RQEIDLRIG
Sbjct: 134  IAFEVMEVCTSINHRLNVWRAHFSALIDREIHEAVQNLGRPNKLFADAVDVRQEIDLRIG 193

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFAGDDR+VVLSYGPCQFPTLGF+VERYWEIQSHEPEEFW I 
Sbjct: 194  ASFTRFQTMLLRDAFVLDFAGDDRNVVLSYGPCQFPTLGFIVERYWEIQSHEPEEFWTIN 253

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH SDEGT TF W R  L+D++ A I+YEMCVEE TATV NV ++E+LKYPPYPLST+E
Sbjct: 254  CSHTSDEGTTTFSWMRGHLFDYTSAVIVYEMCVEESTATVMNVRNQEKLKYPPYPLSTVE 313

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            LQKRASR  RMSS+HTMKVAEELY +G+ISYPRTETDSFS N DL  IV EQ+GHP WGS
Sbjct: 314  LQKRASRYFRMSSEHTMKVAEELYQAGYISYPRTETDSFSVNTDLHAIVGEQVGHPAWGS 373

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDPE  LWRNP NGGH+DKAHPPIHPTKFSAGE GWS+DHNRLYELVVRHFLACV
Sbjct: 374  YAQRLLDPEASLWRNPSNGGHNDKAHPPIHPTKFSAGEPGWSQDHNRLYELVVRHFLACV 433

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            S+PAVGA TTV+IDIAGEQFSASG VII +NYLDVY ++SW G+I+PTY IGQQF+PTTL
Sbjct: 434  SKPAVGAETTVEIDIAGEQFSASGRVIIAKNYLDVYRFESWGGTILPTYTIGQQFIPTTL 493

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR YATKDS ++FSPTNLG
Sbjct: 494  TLDSGVTRPPQLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRCYATKDSDTRFSPTNLG 553

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYD+MGYELWKP+LR+ ME DMK VS G+KRKS+ L  CLQ++K  FLDAR  +V
Sbjct: 554  EALVMGYDEMGYELWKPFLRSMMECDMKAVSIGSKRKSEVLEGCLQQMKACFLDARLNRV 613

Query: 1801 NLLEAMELFFERSNRPVGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCRN 1980
             L EAMELFFERSNR   D  N GE VRPC++CHES MVLKRR +GDFM GCL FP CRN
Sbjct: 614  KLFEAMELFFERSNRSGADTNNIGETVRPCDSCHESDMVLKRRPSGDFMVGCLRFPLCRN 673

Query: 1981 VVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKDL 2160
            VVWLPG+ISEA+VT+ VC +CAPGPVF IQ KFRRLEIPPNYDVDHLGCIGGCD  L++L
Sbjct: 674  VVWLPGSISEAAVTSEVCPTCAPGPVFLIQFKFRRLEIPPNYDVDHLGCIGGCDVALREL 733

Query: 2161 IEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXXX 2340
             EICGTGSR  TGMTAR QR+ E P+ TRR N RQD+C +CR+TGHSSN+CPSQ      
Sbjct: 734  AEICGTGSRNNTGMTARAQRSTEPPSSTRRGNSRQDSCMYCRRTGHSSNDCPSQ-VSHSH 792

Query: 2341 XXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                       N  GQ+ C SCGA C +RTA TE NRGRKFY+CQ++ECGFFVWED L
Sbjct: 793  GAPSIRIQKSRNGSGQVLC-SCGAPCALRTANTETNRGRKFYTCQSQECGFFVWEDSL 849


>gb|AIC82458.1| topoisomerase 3alpha [Cocos nucifera]
          Length = 916

 Score = 1257 bits (3253), Expect = 0.0
 Identities = 603/836 (72%), Positives = 687/836 (82%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK +S IL               YNR+FEFEY +    CHM+ TSVTGHLME
Sbjct: 14   NVAEKPSVAKAVSEILSRGGGGFRSREGRSRYNRVFEFEYAIGPHLCHMLVTSVTGHLME 73

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            LDF++R+RKWHSCDPA+LY AP++K+VPQDKLDI+RTLEEEAR CQWLVLWLD D EGEN
Sbjct: 74   LDFDDRFRKWHSCDPADLYDAPVRKYVPQDKLDIKRTLEEEARSCQWLVLWLDCDREGEN 133

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV+EVCT++N  + +WRA FS++ ER+I  +VQ+L +PNKL AD+VD RQEIDLRIG
Sbjct: 134  IAFEVVEVCTSINHRLNVWRAHFSALIEREIREAVQNLGRPNKLFADAVDVRQEIDLRIG 193

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFAGDDR+VVLSYGPCQFPTLGF+VERYWEIQSHEPEEFW I 
Sbjct: 194  ASFTRFQTMLLRDAFVLDFAGDDRNVVLSYGPCQFPTLGFIVERYWEIQSHEPEEFWTIN 253

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH SDEGTA F W R  L+D++ A I+YEMCVEEPTATV NV ++E+LKYPPYPL+T+E
Sbjct: 254  CSHTSDEGTAAFSWMRGHLFDYTSAVIVYEMCVEEPTATVMNVRNQEKLKYPPYPLNTVE 313

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            LQKRASR  RMSS+HTMKVAEELY +G+ISYPRTETD FS N DL  IV EQ+GHP WGS
Sbjct: 314  LQKRASRYFRMSSEHTMKVAEELYQAGYISYPRTETDKFSENTDLHAIVGEQVGHPAWGS 373

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDPE RLWRNPGNGGHDDKAHPPIHPTKFSAGE  WS+DHNRLYELVVRHFLACV
Sbjct: 374  YAQRLLDPEARLWRNPGNGGHDDKAHPPIHPTKFSAGEPRWSQDHNRLYELVVRHFLACV 433

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA TTV+IDIAGEQFSASG VII +NYLDVY ++SW G+I+PTY IGQQF+PTTL
Sbjct: 434  SQPAVGAETTVEIDIAGEQFSASGRVIIAKNYLDVYRFESWGGTILPTYTIGQQFVPTTL 493

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR YATKDS ++FSPTNLG
Sbjct: 494  TLDSGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRCYATKDSNTRFSPTNLG 553

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYD+MGYELWKP+LR+ ME DMK VS GTKRK + L  CLQ++K  FLDA+  +V
Sbjct: 554  EALVMGYDEMGYELWKPFLRSMMECDMKAVSMGTKRKFEVLEGCLQQMKACFLDAKLNRV 613

Query: 1801 NLLEAMELFFERSNRPVGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCRN 1980
             LLEAM LFFERSNR   D  N GE VRPC+ CHES MVLKRR NGDFM GCL FP CRN
Sbjct: 614  KLLEAMGLFFERSNRSGADPHNVGETVRPCDLCHESDMVLKRRPNGDFMVGCLRFPLCRN 673

Query: 1981 VVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKDL 2160
            VVWLPG+ISEA+V++ VC +CAPGPV  IQ KFRRLEIPPNYDVDHLGCIGGCD  L++L
Sbjct: 674  VVWLPGSISEAAVSSQVCPTCAPGPVSLIQFKFRRLEIPPNYDVDHLGCIGGCDVTLREL 733

Query: 2161 IEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXXX 2340
             EICGTGSR     TARGQR+ E P+ TR+ N RQD+C +CR+TGHSSN+CPSQ      
Sbjct: 734  AEICGTGSR---NNTARGQRSTEPPSSTRQGNSRQDSCMYCRRTGHSSNDCPSQ-VSRSH 789

Query: 2341 XXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWED 2508
                       N  GQ+ C SCGA C +RTA TE NRGR+FY+C ++ECGFFVWED
Sbjct: 790  RAQPIGIQKSRNGSGQVLC-SCGAPCTLRTANTETNRGRRFYTCPSQECGFFVWED 844


>ref|XP_008807899.1| PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Phoenix dactylifera]
          Length = 917

 Score = 1256 bits (3251), Expect = 0.0
 Identities = 603/838 (71%), Positives = 690/838 (82%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++ IL               YNR+FEFEY +  Q CHM+ TSVTGHLME
Sbjct: 14   NVAEKPSVAKAVAEILSRRGGGFRSREGRSRYNRVFEFEYAIGPQLCHMLVTSVTGHLME 73

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+F++R+RKWHSCDPA+LY A ++K VPQDKLDI+RTLEEEAR CQWLVLWLD D EGEN
Sbjct: 74   LEFDDRFRKWHSCDPADLYHAAVRKHVPQDKLDIKRTLEEEARSCQWLVLWLDCDREGEN 133

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV+EVCT++N  + +WRA FS++ +R+I+ +VQ+L +PNKL AD+VD RQEIDLRIG
Sbjct: 134  IAFEVMEVCTSINHRLNVWRAHFSALIDREIHEAVQNLGRPNKLFADAVDVRQEIDLRIG 193

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFAGDDR+VVLSYGPCQFPTLGF+VERYWEIQSHEPEEFW I 
Sbjct: 194  ASFTRFQTMLLRDAFVLDFAGDDRNVVLSYGPCQFPTLGFIVERYWEIQSHEPEEFWTIN 253

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH SDEGT TF W R  L+D++ A I+YEMCVEE TATV NV ++E+LKYPPYPLST+E
Sbjct: 254  CSHTSDEGTTTFSWMRGHLFDYTSAVIVYEMCVEESTATVMNVRNQEKLKYPPYPLSTVE 313

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            LQKRASR  RMSS+HTMKVAEELY +G+ISYPRTETDSFS N DL  IV EQ+GHP WGS
Sbjct: 314  LQKRASRYFRMSSEHTMKVAEELYQAGYISYPRTETDSFSVNTDLHAIVGEQVGHPAWGS 373

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDPE  LWRNP NGGH+DKAHPPIHPTKFSAGE GWS+DHNRLYELVVRHFLACV
Sbjct: 374  YAQRLLDPEASLWRNPSNGGHNDKAHPPIHPTKFSAGEPGWSQDHNRLYELVVRHFLACV 433

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            S+PAVGA TTV+IDIAGEQFSASG VII +NYLDVY ++SW G+I+PTY IGQQF+PTTL
Sbjct: 434  SKPAVGAETTVEIDIAGEQFSASGRVIIAKNYLDVYRFESWGGTILPTYTIGQQFIPTTL 493

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR YATKDS ++FSPTNLG
Sbjct: 494  TLDSGVTRPPQLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRCYATKDSDTRFSPTNLG 553

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYD+MGYELWKP+LR+ ME DMK VS G+KRKS+ L  CLQ++K  FLDAR  +V
Sbjct: 554  EALVMGYDEMGYELWKPFLRSMMECDMKAVSIGSKRKSEVLEGCLQQMKACFLDARLNRV 613

Query: 1801 NLLEAMELFFERSNRPVGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCRN 1980
             L EAMELFFERSNR   D  N GE VRPC++CHES MVLKRR +GDFM GCL FP CRN
Sbjct: 614  KLFEAMELFFERSNRSGADTNNIGETVRPCDSCHESDMVLKRRPSGDFMVGCLRFPLCRN 673

Query: 1981 VVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKDL 2160
            VVWLPG+ISEA+VT+ VC +CAPGPVF IQ KFRRLEIPPNYDVDHLGCIGGCD  L++L
Sbjct: 674  VVWLPGSISEAAVTSEVCPTCAPGPVFLIQFKFRRLEIPPNYDVDHLGCIGGCDVALREL 733

Query: 2161 IEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXXX 2340
             EICGTGSR     TAR QR+ E P+ TRR N RQD+C +CR+TGHSSN+CPSQ      
Sbjct: 734  AEICGTGSR---NNTARAQRSTEPPSSTRRGNSRQDSCMYCRRTGHSSNDCPSQ-VSHSH 789

Query: 2341 XXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                       N  GQ+ C SCGA C +RTA TE NRGRKFY+CQ++ECGFFVWED L
Sbjct: 790  GAPSIRIQKSRNGSGQVLC-SCGAPCALRTANTETNRGRKFYTCQSQECGFFVWEDSL 846


>ref|XP_010907414.1| PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Elaeis guineensis]
          Length = 917

 Score = 1255 bits (3248), Expect = 0.0
 Identities = 603/836 (72%), Positives = 687/836 (82%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK +S IL               YNR+FEFEY +  Q CHM+ TSVTGHLME
Sbjct: 14   NVAEKPSVAKAVSEILSRRGGGFRSREGRSRYNRVFEFEYAIGPQLCHMLVTSVTGHLME 73

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            LDF++R+RKWHSCDPA+LY AP++K VPQDKLDI+RTLEEEAR CQWLVLWLD D EGEN
Sbjct: 74   LDFDDRFRKWHSCDPADLYDAPVRKNVPQDKLDIKRTLEEEARSCQWLVLWLDCDREGEN 133

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV+EVCT++N  + +WRA FS++ +R+I+ +VQ+L +PNKL AD+VDARQEIDLRIG
Sbjct: 134  IAFEVMEVCTSINHRLNVWRAHFSALIDREIHEAVQNLGRPNKLFADAVDARQEIDLRIG 193

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFAGDDR+VVLSYGPCQFPTLGF+VERYWEIQSHEPEEFW I 
Sbjct: 194  ASFTRFQTMLLRDAFVLDFAGDDRNVVLSYGPCQFPTLGFIVERYWEIQSHEPEEFWTIN 253

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH SDEGTA F W R  L+D++ A I YEMCVEEPTATV  V ++E+LKYPPYPLST+E
Sbjct: 254  CSHTSDEGTAAFSWMRGHLFDYTSAVIAYEMCVEEPTATVMTVRNQEKLKYPPYPLSTVE 313

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            LQKRASR  RMS++HTMKVAEELY +G+ISYPRTETD+FS N DL  IV EQ+GHP WGS
Sbjct: 314  LQKRASRYFRMSAEHTMKVAEELYQAGYISYPRTETDNFSANTDLHAIVGEQVGHPAWGS 373

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDPE RLWRNP NGGHDDKAHPPIHPTKF AGE GWS++HNRLYELVVRHFLACV
Sbjct: 374  YAQRLLDPEARLWRNPSNGGHDDKAHPPIHPTKFFAGEPGWSQNHNRLYELVVRHFLACV 433

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA TTV+IDIAGEQF ASG VII +NYLDVY ++SW G+I+PTY IGQQF+PTTL
Sbjct: 434  SQPAVGAETTVEIDIAGEQFFASGRVIIAKNYLDVYRFESWGGTILPTYTIGQQFIPTTL 493

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR YATKDS ++FSPTNLG
Sbjct: 494  TLDSGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRCYATKDSNTRFSPTNLG 553

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYD+MGYELWKP+LR+ ME DMK VS G KRKS+ L  CLQ++K  FLDAR  +V
Sbjct: 554  EALVMGYDEMGYELWKPFLRSMMECDMKAVSLGAKRKSEVLEGCLQQMKACFLDARLNRV 613

Query: 1801 NLLEAMELFFERSNRPVGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCRN 1980
             LLEAM LFFERSNR   D  N GE VR C+ CHES MVLKRR NGDFM GCL FP CRN
Sbjct: 614  KLLEAMGLFFERSNRSGADTHNIGETVRSCDLCHESDMVLKRRPNGDFMVGCLRFPLCRN 673

Query: 1981 VVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKDL 2160
            VVWLPG+ISEA+V++ VC +CAPGPVF IQ KFRRLEIPPNYDVDHLGCIGGCD  L++L
Sbjct: 674  VVWLPGSISEAAVSSQVCPTCAPGPVFLIQFKFRRLEIPPNYDVDHLGCIGGCDVTLREL 733

Query: 2161 IEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXXX 2340
             EICGTGSR     TARGQR+ E P+ TRR N RQD+C +CR+TGHSSN+CPSQ      
Sbjct: 734  AEICGTGSR---NNTARGQRSTEPPSSTRRGNSRQDSCMYCRRTGHSSNDCPSQ-VSRSH 789

Query: 2341 XXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWED 2508
                       N  GQ+ C SCGA C +RTA TE NRGR+FY+CQ++ECGFFVWED
Sbjct: 790  RAQSIGIQKSRNGSGQVLC-SCGAPCALRTANTESNRGRRFYTCQSQECGFFVWED 844


>gb|PKU87668.1| DNA topoisomerase III [Dendrobium catenatum]
          Length = 953

 Score = 1229 bits (3180), Expect = 0.0
 Identities = 587/838 (70%), Positives = 675/838 (80%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++ IL               YNR+FEFEYT+  Q CHM+ TSVTGHLME
Sbjct: 11   NVAEKPSVAKSVAEILSRGGSGMRSREGRSRYNRVFEFEYTIGGQLCHMLMTSVTGHLME 70

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            +DFE+R+RKWHSCDPA+LY AP++K+VPQDKLD++RTLEEE+R+C WLVLWLD D EGEN
Sbjct: 71   IDFEDRFRKWHSCDPADLYHAPIRKYVPQDKLDLKRTLEEESRRCHWLVLWLDCDREGEN 130

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV++VCT+ N H+ IWRA FS++ +R+I+ SVQ+L +PNKL AD+VDARQEIDLRIG
Sbjct: 131  IAFEVVDVCTSANSHLNIWRARFSALIDREIHASVQNLVRPNKLFADAVDARQEIDLRIG 190

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFAGDDRS+VLSYGPCQFPTLGF+VERYWEIQ+HEPEEFW I 
Sbjct: 191  ASFTRFQTMLLRDAFVLDFAGDDRSIVLSYGPCQFPTLGFIVERYWEIQAHEPEEFWTIN 250

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH S+EGTATF W R  L+D++CA IIYEMCVE+P ATV +V HKE+LKYPPYPLST+E
Sbjct: 251  CSHTSEEGTATFSWMRGHLFDYTCAVIIYEMCVEDPMATVTDVKHKEKLKYPPYPLSTVE 310

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            LQKRASR  RMSS+HTMKVAEELY +GFISYPRTETD FS N DL  IVREQ+  PTWG 
Sbjct: 311  LQKRASRFFRMSSEHTMKVAEELYQAGFISYPRTETDGFSVNTDLHAIVREQVVDPTWGP 370

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQQLLDPE RLWRNP NGGHDDKAHPPIHPTK  AG  GW+ DH RLYE VVRHFLACV
Sbjct: 371  YAQQLLDPEVRLWRNPSNGGHDDKAHPPIHPTKLFAGVPGWTEDHKRLYEFVVRHFLACV 430

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA T V+IDIAGEQFSA+G VI  RNYLD+Y ++SW G +IPTY I QQF+PT L
Sbjct: 431  SQPAVGAETKVEIDIAGEQFSATGLVIKARNYLDIYRFESWGGVVIPTYNIEQQFIPTIL 490

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR+YATKD+ ++FSPT LG
Sbjct: 491  TLDSGVTRPPPLLSESDLLSCMDKAGIGTDATMHDHIKKLLDRHYATKDANTRFSPTKLG 550

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYDDMGYELWKPYLR+ ME DMK+VS G+K KS  L SCLQ++K  FLDAR+ K+
Sbjct: 551  EALVMGYDDMGYELWKPYLRSMMECDMKEVSMGSKSKSQVLESCLQQMKACFLDARQNKI 610

Query: 1801 NLLEAMELFFERSNRPVGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCRN 1980
             LL+AME+FFERS R  GD QN G  V  C  C+ES M+LKRR NGDFM GC  FP CRN
Sbjct: 611  KLLDAMEMFFERSGRS-GDAQNFGATVMQCGVCNESDMLLKRRPNGDFMVGCQRFPLCRN 669

Query: 1981 VVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKDL 2160
            VVWLPGAIS+A+VT N+C  C PGPVF IQ KFRR+EIPPNYDVDHLGC+GGCD IL++L
Sbjct: 670  VVWLPGAISDANVTGNICPRCTPGPVFLIQFKFRRMEIPPNYDVDHLGCVGGCDDILREL 729

Query: 2161 IEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXXX 2340
            +EICGTGSR AT MTARGQ   + PN T R N     C+ CRQ GHSSN+CPSQ      
Sbjct: 730  VEICGTGSRNATPMTARGQ-TSDPPNATNRRNTGSTPCSRCRQAGHSSNDCPSQ--VSRS 786

Query: 2341 XXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                       N+ G I C +CG  C +RTA TE NRGRKFY+CQ+R C FFVWE++L
Sbjct: 787  CRAQSTISNSRNSAGPILC-NCGEPCTLRTANTESNRGRKFYACQSRNCDFFVWEENL 843


>ref|XP_020673261.1| DNA topoisomerase 3-alpha isoform X5 [Dendrobium catenatum]
          Length = 915

 Score = 1229 bits (3180), Expect = 0.0
 Identities = 587/838 (70%), Positives = 675/838 (80%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++ IL               YNR+FEFEYT+  Q CHM+ TSVTGHLME
Sbjct: 11   NVAEKPSVAKSVAEILSRGGSGMRSREGRSRYNRVFEFEYTIGGQLCHMLMTSVTGHLME 70

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            +DFE+R+RKWHSCDPA+LY AP++K+VPQDKLD++RTLEEE+R+C WLVLWLD D EGEN
Sbjct: 71   IDFEDRFRKWHSCDPADLYHAPIRKYVPQDKLDLKRTLEEESRRCHWLVLWLDCDREGEN 130

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV++VCT+ N H+ IWRA FS++ +R+I+ SVQ+L +PNKL AD+VDARQEIDLRIG
Sbjct: 131  IAFEVVDVCTSANSHLNIWRARFSALIDREIHASVQNLVRPNKLFADAVDARQEIDLRIG 190

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFAGDDRS+VLSYGPCQFPTLGF+VERYWEIQ+HEPEEFW I 
Sbjct: 191  ASFTRFQTMLLRDAFVLDFAGDDRSIVLSYGPCQFPTLGFIVERYWEIQAHEPEEFWTIN 250

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH S+EGTATF W R  L+D++CA IIYEMCVE+P ATV +V HKE+LKYPPYPLST+E
Sbjct: 251  CSHTSEEGTATFSWMRGHLFDYTCAVIIYEMCVEDPMATVTDVKHKEKLKYPPYPLSTVE 310

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            LQKRASR  RMSS+HTMKVAEELY +GFISYPRTETD FS N DL  IVREQ+  PTWG 
Sbjct: 311  LQKRASRFFRMSSEHTMKVAEELYQAGFISYPRTETDGFSVNTDLHAIVREQVVDPTWGP 370

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQQLLDPE RLWRNP NGGHDDKAHPPIHPTK  AG  GW+ DH RLYE VVRHFLACV
Sbjct: 371  YAQQLLDPEVRLWRNPSNGGHDDKAHPPIHPTKLFAGVPGWTEDHKRLYEFVVRHFLACV 430

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA T V+IDIAGEQFSA+G VI  RNYLD+Y ++SW G +IPTY I QQF+PT L
Sbjct: 431  SQPAVGAETKVEIDIAGEQFSATGLVIKARNYLDIYRFESWGGVVIPTYNIEQQFIPTIL 490

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR+YATKD+ ++FSPT LG
Sbjct: 491  TLDSGVTRPPPLLSESDLLSCMDKAGIGTDATMHDHIKKLLDRHYATKDANTRFSPTKLG 550

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYDDMGYELWKPYLR+ ME DMK+VS G+K KS  L SCLQ++K  FLDAR+ K+
Sbjct: 551  EALVMGYDDMGYELWKPYLRSMMECDMKEVSMGSKSKSQVLESCLQQMKACFLDARQNKI 610

Query: 1801 NLLEAMELFFERSNRPVGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCRN 1980
             LL+AME+FFERS R  GD QN G  V  C  C+ES M+LKRR NGDFM GC  FP CRN
Sbjct: 611  KLLDAMEMFFERSGRS-GDAQNFGATVMQCGVCNESDMLLKRRPNGDFMVGCQRFPLCRN 669

Query: 1981 VVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKDL 2160
            VVWLPGAIS+A+VT N+C  C PGPVF IQ KFRR+EIPPNYDVDHLGC+GGCD IL++L
Sbjct: 670  VVWLPGAISDANVTGNICPRCTPGPVFLIQFKFRRMEIPPNYDVDHLGCVGGCDDILREL 729

Query: 2161 IEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXXX 2340
            +EICGTGSR AT MTARGQ   + PN T R N     C+ CRQ GHSSN+CPSQ      
Sbjct: 730  VEICGTGSRNATPMTARGQ-TSDPPNATNRRNTGSTPCSRCRQAGHSSNDCPSQ--VSRS 786

Query: 2341 XXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                       N+ G I C +CG  C +RTA TE NRGRKFY+CQ+R C FFVWE++L
Sbjct: 787  CRAQSTISNSRNSAGPILC-NCGEPCTLRTANTESNRGRKFYACQSRNCDFFVWEENL 843


>ref|XP_010649354.1| PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Vitis vinifera]
          Length = 918

 Score = 1222 bits (3161), Expect = 0.0
 Identities = 580/839 (69%), Positives = 680/839 (81%), Gaps = 1/839 (0%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++TIL               YN++FEF Y++R Q C M+ TSV GHLME
Sbjct: 5    NVAEKPSVAKAVATILSRNQGLRVREGRSR-YNKLFEFNYSIRGQHCQMVVTSVIGHLME 63

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+FE+R+RKWHSCDPA LY AP++KFVP+DKLDI+RTLEEEARKCQWLVLWLD D EGEN
Sbjct: 64   LEFEDRFRKWHSCDPAHLYHAPVRKFVPEDKLDIKRTLEEEARKCQWLVLWLDCDREGEN 123

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV+EVC  VNRHI +WRA FS++ +R+I+ SVQ+L +PN+L AD+VD RQEIDLRIG
Sbjct: 124  IAFEVLEVCAQVNRHIDVWRARFSALIDREIHESVQNLVRPNQLFADAVDVRQEIDLRIG 183

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFA DDR++VLSYGPCQFPTLGFVVERYWEIQSHEPEEFW I 
Sbjct: 184  ASFTRFQTMLLRDAFVLDFAADDRNLVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTIN 243

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSHKSDEGT+TF W R  L+D++CA IIYEMC++EPTATV  V  +E+LKYPP+PL+T+E
Sbjct: 244  CSHKSDEGTSTFNWMRAHLFDYTCAVIIYEMCIQEPTATVTKVRQQEKLKYPPHPLNTIE 303

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            L+KRASR   MSS+HTMKVAE+LY +GFISYPRTETD FS   DL GIV+EQ+GHP WGS
Sbjct: 304  LEKRASRYFHMSSEHTMKVAEDLYQTGFISYPRTETDYFSERTDLHGIVQEQLGHPIWGS 363

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDP   LWRNP NGGHDDKAHPPIHPTKFSAGESGWS+DH RLYELVVRHFLACV
Sbjct: 364  YAQRLLDPGAGLWRNPSNGGHDDKAHPPIHPTKFSAGESGWSQDHQRLYELVVRHFLACV 423

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA T V+IDIAGE FS+SG VII +NYLDVY ++SW GS+IPTYV GQQF+PTTL
Sbjct: 424  SQPAVGAETIVEIDIAGESFSSSGRVIIAKNYLDVYRFESWGGSMIPTYVFGQQFIPTTL 483

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L++ M KAGIGTDAT  DHIKKLLDR+YATKDS ++FSPTNLG
Sbjct: 484  TLDSGVTRPPPLLSEADLLNCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRFSPTNLG 543

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYDDMGYELWKPYLR+ ME DMK VS GTKR+++ L +CL+++K  FLDAR  KV
Sbjct: 544  EALVMGYDDMGYELWKPYLRSMMECDMKAVSIGTKRRNEVLTTCLEQMKACFLDARLNKV 603

Query: 1801 NLLEAMELFFERSNRPVGDGQN-AGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCR 1977
             LLEAM LFFERSNR  GD Q+  G+VVR C  C ES MVL+R+ +G+FM GCL +P CR
Sbjct: 604  KLLEAMALFFERSNRSSGDEQHEVGDVVRQCTLCQESDMVLRRKPDGNFMVGCLGYPQCR 663

Query: 1978 NVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKD 2157
            NVVWLPG+ISEA++TT  C+ C PGPV+KIQ KFRRLEIPPNY++DHLGC+ GCD IL+ 
Sbjct: 664  NVVWLPGSISEAAITTISCNHCTPGPVYKIQFKFRRLEIPPNYNIDHLGCVCGCDEILRQ 723

Query: 2158 LIEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXX 2337
            L EICGTGSR+ + + ARG+ +  +    +R N RQ  C HC QTGHSSN+CPS+     
Sbjct: 724  LTEICGTGSRICSTVPARGRGSNASSTNAQRSNTRQTACIHCSQTGHSSNDCPSR--VPR 781

Query: 2338 XXXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                        +    I C  CG  C +RTA TE+NRGRKFYSCQ++EC FFVWED L
Sbjct: 782  SRNSQSHRTNMPSGESSIPCNVCGTPCILRTANTENNRGRKFYSCQSQECNFFVWEDSL 840


>ref|XP_020259033.1| DNA topoisomerase 3-alpha [Asparagus officinalis]
 gb|ONK76464.1| uncharacterized protein A4U43_C03F28160 [Asparagus officinalis]
          Length = 828

 Score = 1221 bits (3158), Expect = 0.0
 Identities = 587/752 (78%), Positives = 642/752 (85%)
 Frame = +1

Query: 265  QDKLDIRRTLEEEARKCQWLVLWLDGDSEGENIAFEVIEVCTAVNRHITIWRALFSSVTE 444
            QDKLDI+RTLEEEAR  QWLVLWLD D EGENIAFEV++VCTAVN  + IWRA FS++ E
Sbjct: 2    QDKLDIKRTLEEEARNSQWLVLWLDCDREGENIAFEVVDVCTAVNHRLVIWRAHFSALNE 61

Query: 445  RDIYTSVQDLRQPNKLLADSVDARQEIDLRIGASFTRFQTMLLKDAFVLDFAGDDRSVVL 624
             DI  SVQ+L QPNKL +D+VDARQEIDLRIGASFTRFQTMLLKDAFVLDF GDDRSVVL
Sbjct: 62   GDILASVQNLVQPNKLFSDAVDARQEIDLRIGASFTRFQTMLLKDAFVLDFPGDDRSVVL 121

Query: 625  SYGPCQFPTLGFVVERYWEIQSHEPEEFWKITCSHKSDEGTATFEWKRERLYDHSCAGII 804
            SYGPCQFPTLGF+VERYWEIQ+HEPEEFW I CSH SDEGT  F+W  +R +D++CA   
Sbjct: 122  SYGPCQFPTLGFIVERYWEIQAHEPEEFWTINCSHTSDEGTTIFKWIYDRSFDYTCAVAT 181

Query: 805  YEMCVEEPTATVKNVCHKERLKYPPYPLSTLELQKRASRCLRMSSDHTMKVAEELYMSGF 984
            YEMCVEEPTATVKNV H E L+YPPYPLST++L KRAS  L MSS+ TMKVAEELYMSGF
Sbjct: 182  YEMCVEEPTATVKNVKHVEELRYPPYPLSTVQLLKRASTYLGMSSERTMKVAEELYMSGF 241

Query: 985  ISYPRTETDSFSGNNDLKGIVREQIGHPTWGSYAQQLLDPERRLWRNPGNGGHDDKAHPP 1164
            ISYPRTETDSFS N+DLK +VREQIGHPTWGSYAQ LLDP+ RLWRNPGNGGHDDKAHPP
Sbjct: 242  ISYPRTETDSFSANSDLKVMVREQIGHPTWGSYAQLLLDPQSRLWRNPGNGGHDDKAHPP 301

Query: 1165 IHPTKFSAGESGWSRDHNRLYELVVRHFLACVSQPAVGAGTTVDIDIAGEQFSASGCVII 1344
            IHPTKFS+GESGWS+DHNRLYELVVRHFLACVSQPAVGA TTV+IDIAG QFSASG  I+
Sbjct: 302  IHPTKFSSGESGWSQDHNRLYELVVRHFLACVSQPAVGAKTTVEIDIAGAQFSASGRTIL 361

Query: 1345 ERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTLKLESGVTRPPSLLTEVELISSMAKAGIG 1524
             +NYLDVY YDSW  S+IP YV+GQQFLPTTL L+SG+TRPP LL E +LI  M KAGIG
Sbjct: 362  AKNYLDVYKYDSWGASVIPAYVLGQQFLPTTLTLDSGLTRPPPLLKEADLIGCMDKAGIG 421

Query: 1525 TDATTADHIKKLLDRYYATKDSRSQFSPTNLGEALVMGYDDMGYELWKPYLRAKMEEDMK 1704
            TDAT  DHIKKLLDR+YA KD  + FSPT LGEALVMGYDDMGYELWKPYLR+KMEEDMK
Sbjct: 422  TDATMQDHIKKLLDRHYARKDPNTFFSPTTLGEALVMGYDDMGYELWKPYLRSKMEEDMK 481

Query: 1705 KVSTGTKRKSDFLASCLQEVKQVFLDARRQKVNLLEAMELFFERSNRPVGDGQNAGEVVR 1884
            +VS GTKRKS+ L SCL+EVK VF+DARR+K NLLEAMELFFERSNRP GD  N GEVVR
Sbjct: 482  EVSIGTKRKSEVLESCLREVKAVFVDARRRKENLLEAMELFFERSNRPAGDAHNGGEVVR 541

Query: 1885 PCNACHESHMVLKRRLNGDFMAGCLNFPHCRNVVWLPGAISEASVTTNVCSSCAPGPVFK 2064
             CNACHES MVL+R+LNG  M GCL+FP CRNVVWLPGA +EA VTTN+CSSC PGPVFK
Sbjct: 542  RCNACHESDMVLRRKLNGGLMVGCLSFPLCRNVVWLPGATAEAIVTTNLCSSCVPGPVFK 601

Query: 2065 IQLKFRRLEIPPNYDVDHLGCIGGCDSILKDLIEICGTGSRMATGMTARGQRAGETPNRT 2244
            IQ KFRRLEIPPNYDVDHLGCIGGCD+IL++LIEICGTGSRM +G  ARGQ AGETPN T
Sbjct: 602  IQFKFRRLEIPPNYDVDHLGCIGGCDAILRELIEICGTGSRMPSGCPARGQTAGETPNST 661

Query: 2245 RRENPRQDTCAHCRQTGHSSNECPSQGFXXXXXXXXXXXXXXXNNIGQIACESCGASCPV 2424
            RR N  QD C HCRQTGHSSNECPSQG                NNIGQI CESCGASCPV
Sbjct: 662  RRGNLGQDVCPHCRQTGHSSNECPSQG-SRSRSAQSSRVQNSRNNIGQIPCESCGASCPV 720

Query: 2425 RTATTEHNRGRKFYSCQNRECGFFVWEDDLAT 2520
            RTA TE NRGRKF+SCQN+ECGFFVW+D+L +
Sbjct: 721  RTAATEQNRGRKFFSCQNQECGFFVWDDNLGS 752


>ref|XP_010649353.1| PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Vitis vinifera]
          Length = 919

 Score = 1218 bits (3151), Expect = 0.0
 Identities = 581/840 (69%), Positives = 680/840 (80%), Gaps = 2/840 (0%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++TIL               YN++FEF Y++R Q C M+ TSV GHLME
Sbjct: 5    NVAEKPSVAKAVATILSRNQGLRVREGRSR-YNKLFEFNYSIRGQHCQMVVTSVIGHLME 63

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+FE+R+RKWHSCDPA LY AP++KFVP+DKLDI+RTLEEEARKCQWLVLWLD D EGEN
Sbjct: 64   LEFEDRFRKWHSCDPAHLYHAPVRKFVPEDKLDIKRTLEEEARKCQWLVLWLDCDREGEN 123

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV+EVC  VNRHI +WRA FS++ +R+I+ SVQ+L +PN+L AD+VD RQEIDLRIG
Sbjct: 124  IAFEVLEVCAQVNRHIDVWRARFSALIDREIHESVQNLVRPNQLFADAVDVRQEIDLRIG 183

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFA DDR++VLSYGPCQFPTLGFVVERYWEIQSHEPEEFW I 
Sbjct: 184  ASFTRFQTMLLRDAFVLDFAADDRNLVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTIN 243

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSHKSDEGT+TF W R  L+D++CA IIYEMC++EPTATV  V  +E+LKYPP+PL+T+E
Sbjct: 244  CSHKSDEGTSTFNWMRAHLFDYTCAVIIYEMCIQEPTATVTKVRQQEKLKYPPHPLNTIE 303

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            L+KRASR   MSS+HTMKVAE+LY +GFISYPRTETD FS   DL GIV+EQ+GHP WGS
Sbjct: 304  LEKRASRYFHMSSEHTMKVAEDLYQTGFISYPRTETDYFSERTDLHGIVQEQLGHPIWGS 363

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDP   LWRNP NGGHDDKAHPPIHPTKFSAGESGWS+DH RLYELVVRHFLACV
Sbjct: 364  YAQRLLDPGAGLWRNPSNGGHDDKAHPPIHPTKFSAGESGWSQDHQRLYELVVRHFLACV 423

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA T V+IDIAGE FS+SG VII +NYLDVY ++SW GS+IPTYV GQQF+PTTL
Sbjct: 424  SQPAVGAETIVEIDIAGESFSSSGRVIIAKNYLDVYRFESWGGSMIPTYVFGQQFIPTTL 483

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L++ M KAGIGTDAT  DHIKKLLDR+YATKDS ++FSPTNLG
Sbjct: 484  TLDSGVTRPPPLLSEADLLNCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRFSPTNLG 543

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYDDMGYELWKPYLR+ ME DMK VS GTKR+++ L +CL+++K  FLDAR  KV
Sbjct: 544  EALVMGYDDMGYELWKPYLRSMMECDMKAVSIGTKRRNEVLTTCLEQMKACFLDARLNKV 603

Query: 1801 NLLEAMELFFERSNRPVGDGQN-AGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCR 1977
             LLEAM LFFERSNR  GD Q+  G+VVR C  C ES MVL+R+ +G+FM GCL +P CR
Sbjct: 604  KLLEAMALFFERSNRSSGDEQHEVGDVVRQCTLCQESDMVLRRKPDGNFMVGCLGYPQCR 663

Query: 1978 NVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKD 2157
            NVVWLPG+ISEA++TT  C+ C PGPV+KIQ KFRRLEIPPNY++DHLGC+ GCD IL+ 
Sbjct: 664  NVVWLPGSISEAAITTISCNHCTPGPVYKIQFKFRRLEIPPNYNIDHLGCVCGCDEILRQ 723

Query: 2158 LIEICGTGSRM-ATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXX 2334
            L EICGTGSR+ +T   ARG+ +  +    +R N RQ  C HC QTGHSSN+CPS+    
Sbjct: 724  LTEICGTGSRICSTVPAARGRGSNASSTNAQRSNTRQTACIHCSQTGHSSNDCPSR--VP 781

Query: 2335 XXXXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                         +    I C  CG  C +RTA TE+NRGRKFYSCQ++EC FFVWED L
Sbjct: 782  RSRNSQSHRTNMPSGESSIPCNVCGTPCILRTANTENNRGRKFYSCQSQECNFFVWEDSL 841


>ref|XP_020673257.1| DNA topoisomerase 3-alpha isoform X1 [Dendrobium catenatum]
          Length = 942

 Score = 1215 bits (3144), Expect = 0.0
 Identities = 587/864 (67%), Positives = 675/864 (78%), Gaps = 26/864 (3%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++ IL               YNR+FEFEYT+  Q CHM+ TSVTGHLME
Sbjct: 11   NVAEKPSVAKSVAEILSRGGSGMRSREGRSRYNRVFEFEYTIGGQLCHMLMTSVTGHLME 70

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            +DFE+R+RKWHSCDPA+LY AP++K+VPQDKLD++RTLEEE+R+C WLVLWLD D EGEN
Sbjct: 71   IDFEDRFRKWHSCDPADLYHAPIRKYVPQDKLDLKRTLEEESRRCHWLVLWLDCDREGEN 130

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV++VCT+ N H+ IWRA FS++ +R+I+ SVQ+L +PNKL AD+VDARQEIDLRIG
Sbjct: 131  IAFEVVDVCTSANSHLNIWRARFSALIDREIHASVQNLVRPNKLFADAVDARQEIDLRIG 190

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFAGDDRS+VLSYGPCQFPTLGF+VERYWEIQ+HEPEEFW I 
Sbjct: 191  ASFTRFQTMLLRDAFVLDFAGDDRSIVLSYGPCQFPTLGFIVERYWEIQAHEPEEFWTIN 250

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKN------------------ 846
            CSH S+EGTATF W R  L+D++CA IIYEMCVE+P ATV +                  
Sbjct: 251  CSHTSEEGTATFSWMRGHLFDYTCAVIIYEMCVEDPMATVSHLLMFPSCRLVSLMSLIDK 310

Query: 847  --------VCHKERLKYPPYPLSTLELQKRASRCLRMSSDHTMKVAEELYMSGFISYPRT 1002
                    V HKE+LKYPPYPLST+ELQKRASR  RMSS+HTMKVAEELY +GFISYPRT
Sbjct: 311  KIIFQVTDVKHKEKLKYPPYPLSTVELQKRASRFFRMSSEHTMKVAEELYQAGFISYPRT 370

Query: 1003 ETDSFSGNNDLKGIVREQIGHPTWGSYAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKF 1182
            ETD FS N DL  IVREQ+  PTWG YAQQLLDPE RLWRNP NGGHDDKAHPPIHPTK 
Sbjct: 371  ETDGFSVNTDLHAIVREQVVDPTWGPYAQQLLDPEVRLWRNPSNGGHDDKAHPPIHPTKL 430

Query: 1183 SAGESGWSRDHNRLYELVVRHFLACVSQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLD 1362
             AG  GW+ DH RLYE VVRHFLACVSQPAVGA T V+IDIAGEQFSA+G VI  RNYLD
Sbjct: 431  FAGVPGWTEDHKRLYEFVVRHFLACVSQPAVGAETKVEIDIAGEQFSATGLVIKARNYLD 490

Query: 1363 VYPYDSWDGSIIPTYVIGQQFLPTTLKLESGVTRPPSLLTEVELISSMAKAGIGTDATTA 1542
            +Y ++SW G +IPTY I QQF+PT L L+SGVTRPP LL+E +L+S M KAGIGTDAT  
Sbjct: 491  IYRFESWGGVVIPTYNIEQQFIPTILTLDSGVTRPPPLLSESDLLSCMDKAGIGTDATMH 550

Query: 1543 DHIKKLLDRYYATKDSRSQFSPTNLGEALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGT 1722
            DHIKKLLDR+YATKD+ ++FSPT LGEALVMGYDDMGYELWKPYLR+ ME DMK+VS G+
Sbjct: 551  DHIKKLLDRHYATKDANTRFSPTKLGEALVMGYDDMGYELWKPYLRSMMECDMKEVSMGS 610

Query: 1723 KRKSDFLASCLQEVKQVFLDARRQKVNLLEAMELFFERSNRPVGDGQNAGEVVRPCNACH 1902
            K KS  L SCLQ++K  FLDAR+ K+ LL+AME+FFERS R  GD QN G  V  C  C+
Sbjct: 611  KSKSQVLESCLQQMKACFLDARQNKIKLLDAMEMFFERSGRS-GDAQNFGATVMQCGVCN 669

Query: 1903 ESHMVLKRRLNGDFMAGCLNFPHCRNVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFR 2082
            ES M+LKRR NGDFM GC  FP CRNVVWLPGAIS+A+VT N+C  C PGPVF IQ KFR
Sbjct: 670  ESDMLLKRRPNGDFMVGCQRFPLCRNVVWLPGAISDANVTGNICPRCTPGPVFLIQFKFR 729

Query: 2083 RLEIPPNYDVDHLGCIGGCDSILKDLIEICGTGSRMATGMTARGQRAGETPNRTRRENPR 2262
            R+EIPPNYDVDHLGC+GGCD IL++L+EICGTGSR AT MTARGQ   + PN T R N  
Sbjct: 730  RMEIPPNYDVDHLGCVGGCDDILRELVEICGTGSRNATPMTARGQ-TSDPPNATNRRNTG 788

Query: 2263 QDTCAHCRQTGHSSNECPSQGFXXXXXXXXXXXXXXXNNIGQIACESCGASCPVRTATTE 2442
               C+ CRQ GHSSN+CPSQ                 N+ G I C +CG  C +RTA TE
Sbjct: 789  STPCSRCRQAGHSSNDCPSQ--VSRSCRAQSTISNSRNSAGPILC-NCGEPCTLRTANTE 845

Query: 2443 HNRGRKFYSCQNRECGFFVWEDDL 2514
             NRGRKFY+CQ+R C FFVWE++L
Sbjct: 846  SNRGRKFYACQSRNCDFFVWEENL 869


>ref|XP_020673258.1| DNA topoisomerase 3-alpha isoform X2 [Dendrobium catenatum]
 ref|XP_020673259.1| DNA topoisomerase 3-alpha isoform X3 [Dendrobium catenatum]
          Length = 941

 Score = 1215 bits (3144), Expect = 0.0
 Identities = 587/864 (67%), Positives = 675/864 (78%), Gaps = 26/864 (3%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++ IL               YNR+FEFEYT+  Q CHM+ TSVTGHLME
Sbjct: 11   NVAEKPSVAKSVAEILSRGGSGMRSREGRSRYNRVFEFEYTIGGQLCHMLMTSVTGHLME 70

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            +DFE+R+RKWHSCDPA+LY AP++K+VPQDKLD++RTLEEE+R+C WLVLWLD D EGEN
Sbjct: 71   IDFEDRFRKWHSCDPADLYHAPIRKYVPQDKLDLKRTLEEESRRCHWLVLWLDCDREGEN 130

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV++VCT+ N H+ IWRA FS++ +R+I+ SVQ+L +PNKL AD+VDARQEIDLRIG
Sbjct: 131  IAFEVVDVCTSANSHLNIWRARFSALIDREIHASVQNLVRPNKLFADAVDARQEIDLRIG 190

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFAGDDRS+VLSYGPCQFPTLGF+VERYWEIQ+HEPEEFW I 
Sbjct: 191  ASFTRFQTMLLRDAFVLDFAGDDRSIVLSYGPCQFPTLGFIVERYWEIQAHEPEEFWTIN 250

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKN------------------ 846
            CSH S+EGTATF W R  L+D++CA IIYEMCVE+P ATV +                  
Sbjct: 251  CSHTSEEGTATFSWMRGHLFDYTCAVIIYEMCVEDPMATVSHLLMFPSCRLVSLMSLIDK 310

Query: 847  --------VCHKERLKYPPYPLSTLELQKRASRCLRMSSDHTMKVAEELYMSGFISYPRT 1002
                    V HKE+LKYPPYPLST+ELQKRASR  RMSS+HTMKVAEELY +GFISYPRT
Sbjct: 311  KIIFQVTDVKHKEKLKYPPYPLSTVELQKRASRFFRMSSEHTMKVAEELYQAGFISYPRT 370

Query: 1003 ETDSFSGNNDLKGIVREQIGHPTWGSYAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKF 1182
            ETD FS N DL  IVREQ+  PTWG YAQQLLDPE RLWRNP NGGHDDKAHPPIHPTK 
Sbjct: 371  ETDGFSVNTDLHAIVREQVVDPTWGPYAQQLLDPEVRLWRNPSNGGHDDKAHPPIHPTKL 430

Query: 1183 SAGESGWSRDHNRLYELVVRHFLACVSQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLD 1362
             AG  GW+ DH RLYE VVRHFLACVSQPAVGA T V+IDIAGEQFSA+G VI  RNYLD
Sbjct: 431  FAGVPGWTEDHKRLYEFVVRHFLACVSQPAVGAETKVEIDIAGEQFSATGLVIKARNYLD 490

Query: 1363 VYPYDSWDGSIIPTYVIGQQFLPTTLKLESGVTRPPSLLTEVELISSMAKAGIGTDATTA 1542
            +Y ++SW G +IPTY I QQF+PT L L+SGVTRPP LL+E +L+S M KAGIGTDAT  
Sbjct: 491  IYRFESWGGVVIPTYNIEQQFIPTILTLDSGVTRPPPLLSESDLLSCMDKAGIGTDATMH 550

Query: 1543 DHIKKLLDRYYATKDSRSQFSPTNLGEALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGT 1722
            DHIKKLLDR+YATKD+ ++FSPT LGEALVMGYDDMGYELWKPYLR+ ME DMK+VS G+
Sbjct: 551  DHIKKLLDRHYATKDANTRFSPTKLGEALVMGYDDMGYELWKPYLRSMMECDMKEVSMGS 610

Query: 1723 KRKSDFLASCLQEVKQVFLDARRQKVNLLEAMELFFERSNRPVGDGQNAGEVVRPCNACH 1902
            K KS  L SCLQ++K  FLDAR+ K+ LL+AME+FFERS R  GD QN G  V  C  C+
Sbjct: 611  KSKSQVLESCLQQMKACFLDARQNKIKLLDAMEMFFERSGRS-GDAQNFGATVMQCGVCN 669

Query: 1903 ESHMVLKRRLNGDFMAGCLNFPHCRNVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFR 2082
            ES M+LKRR NGDFM GC  FP CRNVVWLPGAIS+A+VT N+C  C PGPVF IQ KFR
Sbjct: 670  ESDMLLKRRPNGDFMVGCQRFPLCRNVVWLPGAISDANVTGNICPRCTPGPVFLIQFKFR 729

Query: 2083 RLEIPPNYDVDHLGCIGGCDSILKDLIEICGTGSRMATGMTARGQRAGETPNRTRRENPR 2262
            R+EIPPNYDVDHLGC+GGCD IL++L+EICGTGSR AT MTARGQ   + PN T R N  
Sbjct: 730  RMEIPPNYDVDHLGCVGGCDDILRELVEICGTGSRNATPMTARGQ-TSDPPNATNRRNTG 788

Query: 2263 QDTCAHCRQTGHSSNECPSQGFXXXXXXXXXXXXXXXNNIGQIACESCGASCPVRTATTE 2442
               C+ CRQ GHSSN+CPSQ                 N+ G I C +CG  C +RTA TE
Sbjct: 789  STPCSRCRQAGHSSNDCPSQ--VSRSCRAQSTISNSRNSAGPILC-NCGEPCTLRTANTE 845

Query: 2443 HNRGRKFYSCQNRECGFFVWEDDL 2514
             NRGRKFY+CQ+R C FFVWE++L
Sbjct: 846  SNRGRKFYACQSRNCDFFVWEENL 869


>gb|OVA03617.1| DNA topoisomerase [Macleaya cordata]
          Length = 936

 Score = 1215 bits (3143), Expect = 0.0
 Identities = 585/840 (69%), Positives = 684/840 (81%), Gaps = 2/840 (0%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK +S IL               YN+IFEFEYT+R QPC+M  TSVTGHLME
Sbjct: 12   NVAEKPSVAKAVSGILSRNQGLRVREGRSR-YNKIFEFEYTIRGQPCNMAVTSVTGHLME 70

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+FE+RYRKW+SCDP +LY A ++K VPQDKLDI+RTLEEEAR+CQWLVLWLD D EGEN
Sbjct: 71   LEFEDRYRKWNSCDPVDLYQAVVRKLVPQDKLDIKRTLEEEARRCQWLVLWLDCDREGEN 130

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEVIEVCTAVN ++ IWRA FS++ ERDI+ SVQ+L +PN+L AD+VDARQEIDLRIG
Sbjct: 131  IAFEVIEVCTAVNPNLNIWRARFSALIERDIHESVQNLVRPNQLFADAVDARQEIDLRIG 190

Query: 541  ASFTRFQTMLLKDAFVLDFAGDD-RSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKI 717
            ASFTRFQTMLLKDAFVLD +G+D R++VLSYGPCQFPTLGF+VERYWEIQ+HEPEEFW I
Sbjct: 191  ASFTRFQTMLLKDAFVLDGSGNDVRNMVLSYGPCQFPTLGFIVERYWEIQAHEPEEFWTI 250

Query: 718  TCSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTL 897
             C+H S++GTATF W R  ++D+SCA IIYEMCV+EPTATV  V  +++LK PPYPL+T+
Sbjct: 251  NCTHTSEDGTATFNWMRGHMFDYSCAVIIYEMCVQEPTATVTKVRDQQKLKQPPYPLNTI 310

Query: 898  ELQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWG 1077
            EL+KRASR  RMSS+HTMKVAE+LY +GFISYPRTETDSFS   DL  IV+EQ GHP WG
Sbjct: 311  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDSFSERTDLHAIVQEQQGHPVWG 370

Query: 1078 SYAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLAC 1257
            SYAQQLLDP   LWRNP NGGHDDKAHPPIHPTKFSAGESGWS+DHNR+YELVVRHFLAC
Sbjct: 371  SYAQQLLDPGAGLWRNPSNGGHDDKAHPPIHPTKFSAGESGWSQDHNRVYELVVRHFLAC 430

Query: 1258 VSQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTT 1437
            VSQPAVGA TTV+IDIAGE FS SG +II RNYLDVY ++SW GS+IP Y+ GQQF PTT
Sbjct: 431  VSQPAVGAETTVEIDIAGELFSVSGRMIIARNYLDVYRFESWGGSVIPKYLFGQQFTPTT 490

Query: 1438 LKLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNL 1617
            L L+SGVTRPP LL+E +L++ M KAGIGTDAT  DHIKKLLDR+YATKD+ ++FSPTNL
Sbjct: 491  LTLDSGVTRPPPLLSEADLLTCMDKAGIGTDATMHDHIKKLLDRFYATKDANTRFSPTNL 550

Query: 1618 GEALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQK 1797
            GEALVMGYDDMGY+LWKPYLR+ ME DMK VS GTKRKS+ L +CLQ++K  FLDAR QK
Sbjct: 551  GEALVMGYDDMGYKLWKPYLRSMMECDMKAVSLGTKRKSEVLETCLQQMKACFLDARLQK 610

Query: 1798 VNLLEAMELFFERSNRPVGDGQN-AGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHC 1974
            V LLEAM +FF+RSNR  GD Q+  GEVVR C  C ES MVLKR+ +G+FM GCL +P C
Sbjct: 611  VKLLEAMAIFFDRSNRSSGDEQHVGGEVVRQCAVCQESDMVLKRKPDGNFMVGCLGYPQC 670

Query: 1975 RNVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILK 2154
            RNVVWLP +ISEA+VTT VC+SC PGPVF IQ KFR++EIPPNY+V+HLGCIGGCD  L+
Sbjct: 671  RNVVWLPASISEATVTTQVCNSCNPGPVFMIQFKFRQMEIPPNYNVNHLGCIGGCDETLR 730

Query: 2155 DLIEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXX 2334
             L EICGTGSR ++ + ARG     + N T+R + RQ TC HCRQTGHSSN+CPSQ    
Sbjct: 731  QLREICGTGSRSSSSIPARGHGPTASSNTTQRPSTRQGTCTHCRQTGHSSNDCPSQ--TL 788

Query: 2335 XXXXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                         +    + C +CGA+CP+R A T +NRGRKFYSCQ+R+C FFVW D++
Sbjct: 789  HSQSVQSRARNFQSGEPSVMCTTCGAACPLREANTTNNRGRKFYSCQSRDCNFFVWADNV 848


>ref|XP_010270299.1| PREDICTED: DNA topoisomerase 3-alpha [Nelumbo nucifera]
          Length = 921

 Score = 1213 bits (3138), Expect = 0.0
 Identities = 580/839 (69%), Positives = 678/839 (80%), Gaps = 1/839 (0%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++ IL               +NRIFEF+Y++R Q CHM+FTSVTGHLME
Sbjct: 11   NVAEKPSVAKAVAGILSRNQGLRVRNGRSR-FNRIFEFDYSIRGQHCHMLFTSVTGHLME 69

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+FEERYRKWHSCDPA+LY AP++KFVPQDKLDI+RTLEEEARKCQWLVLWLD D EGEN
Sbjct: 70   LEFEERYRKWHSCDPADLYHAPVRKFVPQDKLDIKRTLEEEARKCQWLVLWLDCDREGEN 129

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV+E+C+A N H+ IWRA FS++ +R+I+ SVQ+L +PN+L AD+VDARQEIDLRIG
Sbjct: 130  IAFEVVEICSAANNHLNIWRARFSALIDREIHESVQNLVRPNQLFADAVDARQEIDLRIG 189

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLLKDAFV+DFA DDR++VLSYGPCQFPTLGFVVERYWEIQ+HEPEEFW I 
Sbjct: 190  ASFTRFQTMLLKDAFVIDFATDDRNLVLSYGPCQFPTLGFVVERYWEIQAHEPEEFWTIN 249

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH  DEG ATF W R  ++D++ A IIYEMC  EPTATV  V ++E+LKYPP+PL+T+E
Sbjct: 250  CSHTLDEGIATFNWMRGHIFDYTYAVIIYEMCTLEPTATVTKVKNQEKLKYPPHPLNTIE 309

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            L+KRASR  RMSS+HTMKVAEELY SGFISYPRTETD FS   DL  +V+EQ GHP WGS
Sbjct: 310  LEKRASRYFRMSSEHTMKVAEELYQSGFISYPRTETDCFSARTDLHAMVQEQQGHPLWGS 369

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDPE RLWR+P NGGHDDKAHPPIHPTK+SAGESGWS+DH+RLYELVVRHFLACV
Sbjct: 370  YAQRLLDPEARLWRSPSNGGHDDKAHPPIHPTKYSAGESGWSQDHHRLYELVVRHFLACV 429

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPA+GA T V+IDIAGEQFS SG VI+++NYLDVY ++SW GS+IPTY +GQQF+PT L
Sbjct: 430  SQPAIGAETIVEIDIAGEQFSVSGRVILQKNYLDVYRFESWGGSMIPTYSVGQQFIPTAL 489

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L++ M KAGIGTDAT  DHIKKLLDR YATKDS ++FSPTNLG
Sbjct: 490  TLDSGVTRPPPLLSEADLLNCMDKAGIGTDATMHDHIKKLLDRCYATKDSNTRFSPTNLG 549

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYDDMGYELWKPYLR+ ME DMK VS GTKRK++ L +CLQ++K  FLDAR  KV
Sbjct: 550  EALVMGYDDMGYELWKPYLRSMMECDMKAVSIGTKRKAEVLETCLQQMKACFLDARLNKV 609

Query: 1801 NLLEAMELFFERSNRP-VGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCR 1977
             LLEAM +FFER NRP   + Q A ++VRPC+AC ES+MVLKR+ +G+FM GCL FP CR
Sbjct: 610  KLLEAMAIFFERCNRPGTNEQQGAVDIVRPCSACQESNMVLKRKPDGNFMVGCLGFPQCR 669

Query: 1978 NVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKD 2157
            NVVWLPG+IS A+VT ++C SC+PGPVFKIQ KFRRLEIP +YDVDHLGCIGGCD  LK 
Sbjct: 670  NVVWLPGSISTATVTNHICDSCSPGPVFKIQFKFRRLEIPSDYDVDHLGCIGGCDETLKQ 729

Query: 2158 LIEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXX 2337
            L EICGTGSR     +ARG+    +    +R +  Q  C HCRQTGHSSN+CP+Q     
Sbjct: 730  LTEICGTGSRNPPSTSARGRGTTASSTNAQRVSTMQGVCEHCRQTGHSSNDCPTQ--VSR 787

Query: 2338 XXXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                             ++C SCG  C +RTA T +NRGRKFYSCQ  EC FFVWED +
Sbjct: 788  RQSVRPRGRNSQRGGSSVSCNSCGTLCALRTANTANNRGRKFYSCQ--ECNFFVWEDSV 844


>ref|XP_004502963.1| PREDICTED: DNA topoisomerase 3-alpha [Cicer arietinum]
          Length = 920

 Score = 1205 bits (3117), Expect = 0.0
 Identities = 577/839 (68%), Positives = 668/839 (79%), Gaps = 1/839 (0%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++ IL               YNRIFEF YT+R QPCHM+FTSV GHLME
Sbjct: 10   NVAEKPSVAKSVANILSRNQGLRVRDGRSR-YNRIFEFNYTIRGQPCHMLFTSVIGHLME 68

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+FE+RYRKWHSCDPA+LY AP++K VP+DK DI+RTLEEEAR+CQWLVLWLD D EGEN
Sbjct: 69   LEFEDRYRKWHSCDPADLYHAPVRKSVPEDKKDIKRTLEEEARRCQWLVLWLDCDREGEN 128

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV++VCTA N H+TI RA FS++ +R+I+ +VQ+L +PNK  AD+VDARQEIDLRIG
Sbjct: 129  IAFEVVDVCTAANPHLTIKRARFSALIDREIHQAVQNLVEPNKWFADAVDARQEIDLRIG 188

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTML+KDAF++D   DDR+++LSYGPCQFPTLGFVVERYWEIQ+HEPEEFW I 
Sbjct: 189  ASFTRFQTMLMKDAFIIDTITDDRNIILSYGPCQFPTLGFVVERYWEIQAHEPEEFWSIN 248

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH+SDEG A F W R  L+D++CA IIYEMC EEPTATV NV  +E+LKYPP+PLST+E
Sbjct: 249  CSHRSDEGVANFSWGRGHLFDYTCAVIIYEMCTEEPTATVTNVRQQEKLKYPPHPLSTIE 308

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            L+KRASR  RMSS+HTMKVAEELY SGFISYPRTETD+FS   DL  IV+EQ GHP WG 
Sbjct: 309  LEKRASRYFRMSSEHTMKVAEELYQSGFISYPRTETDNFSSRTDLHAIVQEQQGHPQWGV 368

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDPE  LWRNP  GGHDDKAHPPIHPTKFSAGESGWS+DH +LYELVVRHFLACV
Sbjct: 369  YAQRLLDPEAGLWRNPRGGGHDDKAHPPIHPTKFSAGESGWSQDHRKLYELVVRHFLACV 428

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            S+PAVGA TTV+IDIAGE FSA G VI+E+NYLDVY Y+SW GSIIPTY IGQQF+PTTL
Sbjct: 429  SKPAVGAETTVEIDIAGELFSACGRVILEKNYLDVYQYESWGGSIIPTYTIGQQFIPTTL 488

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP  L+E +L+S M K GIGTDAT  DHIKKLLDR+YATKD+  +F+PTNLG
Sbjct: 489  TLDSGVTRPPPPLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDASMRFTPTNLG 548

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYDDMGY+LWKPYLRA ME DMK VS GTK K++ L + LQ++K  FLDAR  KV
Sbjct: 549  EALVMGYDDMGYKLWKPYLRAVMERDMKSVSEGTKSKTEVLDTSLQQMKACFLDARLNKV 608

Query: 1801 NLLEAMELFFERSNRPVGDGQNA-GEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCR 1977
             LLEAM +FFERSNR  G+ QNA GEVVR C  C ES MVLK+  +G+FM GCL FP CR
Sbjct: 609  KLLEAMGIFFERSNRSGGEEQNAIGEVVRRCGLCRESDMVLKKSRDGNFMVGCLGFPQCR 668

Query: 1978 NVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKD 2157
            N VWLPG++SEA VTTN CS+C PGPV++IQ KFR+LEIPPNYDV+HLGCIGGCD IL  
Sbjct: 669  NAVWLPGSVSEAVVTTNTCSNCTPGPVYRIQFKFRQLEIPPNYDVNHLGCIGGCDEILTQ 728

Query: 2158 LIEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXX 2337
            L EICGTG R    M AR +    +       NPRQ  C +C++TGHSSN+CPSQ     
Sbjct: 729  LTEICGTGPR----MPARPRGPTTSTGNAHHTNPRQAVCMNCQETGHSSNDCPSQTLRSR 784

Query: 2338 XXXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDL 2514
                        +    ++C SCG  C +RTA T +NRGRKFYSC ++EC FFVWEDDL
Sbjct: 785  NARQHGNVMNQQSGEASVSCNSCGTPCVLRTANTANNRGRKFYSCPSQECNFFVWEDDL 843


>ref|XP_019702432.1| PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Elaeis guineensis]
          Length = 892

 Score = 1201 bits (3107), Expect = 0.0
 Identities = 586/836 (70%), Positives = 665/836 (79%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK +S IL               YNR+FEFEY +  Q CHM+ TSVTGHLME
Sbjct: 14   NVAEKPSVAKAVSEILSRRGGGFRSREGRSRYNRVFEFEYAIGPQLCHMLVTSVTGHLME 73

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            LDF++R+RKWHSCDPA+LY AP++K VPQDKLDI+RTLEEEAR CQWLVLWLD D EGEN
Sbjct: 74   LDFDDRFRKWHSCDPADLYDAPVRKNVPQDKLDIKRTLEEEARSCQWLVLWLDCDREGEN 133

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEV+EVCT++N  + +WRA FS++ +R+I+ +VQ+L +PNKL AD+VDARQEIDLRIG
Sbjct: 134  IAFEVMEVCTSINHRLNVWRAHFSALIDREIHEAVQNLGRPNKLFADAVDARQEIDLRIG 193

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFVLDFAGDDR+VVLSYGPCQFPTLGF+VERYWEIQSHEPEEFW I 
Sbjct: 194  ASFTRFQTMLLRDAFVLDFAGDDRNVVLSYGPCQFPTLGFIVERYWEIQSHEPEEFWTIN 253

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH SDEGTA F W R  L+D++ A I YEMCVEEPTATV  V ++E+LKYPPYPLST+E
Sbjct: 254  CSHTSDEGTAAFSWMRGHLFDYTSAVIAYEMCVEEPTATVMTVRNQEKLKYPPYPLSTVE 313

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            LQKRASR  RMS++HTMKVAEELY +G+ISYPRTETD+FS N DL  IV EQ+GHP WGS
Sbjct: 314  LQKRASRYFRMSAEHTMKVAEELYQAGYISYPRTETDNFSANTDLHAIVGEQVGHPAWGS 373

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDPE RLWRNP NGGHDDKAHPPIHPTKF AGE GWS++HNRLYELVVRHFLACV
Sbjct: 374  YAQRLLDPEARLWRNPSNGGHDDKAHPPIHPTKFFAGEPGWSQNHNRLYELVVRHFLACV 433

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA TTV+IDIAGEQF ASG VII                          F+PTTL
Sbjct: 434  SQPAVGAETTVEIDIAGEQFFASGRVII-------------------------AFIPTTL 468

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR YATKDS ++FSPTNLG
Sbjct: 469  TLDSGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRCYATKDSNTRFSPTNLG 528

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYD+MGYELWKP+LR+ ME DMK VS G KRKS+ L  CLQ++K  FLDAR  +V
Sbjct: 529  EALVMGYDEMGYELWKPFLRSMMECDMKAVSLGAKRKSEVLEGCLQQMKACFLDARLNRV 588

Query: 1801 NLLEAMELFFERSNRPVGDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCRN 1980
             LLEAM LFFERSNR   D  N GE VR C+ CHES MVLKRR NGDFM GCL FP CRN
Sbjct: 589  KLLEAMGLFFERSNRSGADTHNIGETVRSCDLCHESDMVLKRRPNGDFMVGCLRFPLCRN 648

Query: 1981 VVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKDL 2160
            VVWLPG+ISEA+V++ VC +CAPGPVF IQ KFRRLEIPPNYDVDHLGCIGGCD  L++L
Sbjct: 649  VVWLPGSISEAAVSSQVCPTCAPGPVFLIQFKFRRLEIPPNYDVDHLGCIGGCDVTLREL 708

Query: 2161 IEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXXX 2340
             EICGTGSR     TARGQR+ E P+ TRR N RQD+C +CR+TGHSSN+CPSQ      
Sbjct: 709  AEICGTGSR---NNTARGQRSTEPPSSTRRGNSRQDSCMYCRRTGHSSNDCPSQ-VSRSH 764

Query: 2341 XXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWED 2508
                       N  GQ+ C SCGA C +RTA TE NRGR+FY+CQ++ECGFFVWED
Sbjct: 765  RAQSIGIQKSRNGSGQVLC-SCGAPCALRTANTESNRGRRFYTCQSQECGFFVWED 819


>ref|XP_012489371.1| PREDICTED: DNA topoisomerase 3-alpha isoform X4 [Gossypium raimondii]
 gb|KJB40491.1| hypothetical protein B456_007G066700 [Gossypium raimondii]
 gb|KJB40493.1| hypothetical protein B456_007G066700 [Gossypium raimondii]
          Length = 909

 Score = 1200 bits (3104), Expect = 0.0
 Identities = 572/840 (68%), Positives = 674/840 (80%), Gaps = 1/840 (0%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK +S  L               YNRIFEF Y++R QPCHM+FTSVTGHLME
Sbjct: 9    NVAEKPSVAKSVSGFLSRNQALRVRDGRSR-YNRIFEFNYSIRGQPCHMLFTSVTGHLME 67

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+FE+R+RKWHSCDP +LY AP++KFVP+DKLDI+RTLEEEAR+CQWLVLWLD D EGEN
Sbjct: 68   LEFEDRFRKWHSCDPLDLYHAPVRKFVPEDKLDIKRTLEEEARRCQWLVLWLDCDREGEN 127

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEVI VC AVNRH+TI RA FS++ +R+I+ ++Q+L  PN   +D+VDARQEIDLRIG
Sbjct: 128  IAFEVINVCRAVNRHLTIRRARFSALIDREIHHAMQNLIDPNPWFSDAVDARQEIDLRIG 187

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+D FV+D A DDR++VLSYGPCQFPTLGFVVERYWE+QSHEPEEFW I 
Sbjct: 188  ASFTRFQTMLLRDKFVIDSATDDRNLVLSYGPCQFPTLGFVVERYWEVQSHEPEEFWTIN 247

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH+SDEG ATF W R  L+D++CA I+YEMCV+EPTATV  V HKE+LKYPPYPL+T+E
Sbjct: 248  CSHRSDEGVATFNWMRGHLFDYTCAVIVYEMCVQEPTATVTKVQHKEKLKYPPYPLNTIE 307

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            L+KRASR  RMSS+HTMKVAEELY +GFISYPRTETD FS   DL  IV+EQ GHP WGS
Sbjct: 308  LEKRASRYFRMSSEHTMKVAEELYQAGFISYPRTETDCFSSRTDLHAIVQEQQGHPDWGS 367

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDPE  LWRNPG+GGHDDKAHPPIHPTKFS GE GWS+DH  LYELVVRHFLACV
Sbjct: 368  YAQRLLDPETGLWRNPGSGGHDDKAHPPIHPTKFSTGEHGWSQDHRTLYELVVRHFLACV 427

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA TTV+IDIAGE FSASG VI+ERNYLDVY Y+SW GS+IPTY +GQQF+P +L
Sbjct: 428  SQPAVGAETTVEIDIAGELFSASGRVILERNYLDVYRYESWGGSMIPTYTVGQQFVPASL 487

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L++GVTRPP LL+E +L+S M KAGIGTDAT  DHIKKLLDR+YATKDS ++FSPTNLG
Sbjct: 488  TLDTGVTRPPPLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRFSPTNLG 547

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYDDMGYELWKP LR+ ME DMK+VS G K K + LA+CLQ++K  F DAR  KV
Sbjct: 548  EALVMGYDDMGYELWKPNLRSMMEFDMKEVSVGNKSKDEVLATCLQQMKACFFDARLNKV 607

Query: 1801 NLLEAMELFFERSNRPV-GDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCR 1977
             LLEAM +FFERSNR V GD   AGEVVR C+ C ES MVLK+  +G+FM GC  FP CR
Sbjct: 608  KLLEAMAVFFERSNRAVGGDNYAAGEVVRQCDLCQESSMVLKKNRDGNFMVGCSGFPQCR 667

Query: 1978 NVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKD 2157
            N +WLPG+I EA+VT+N+CSSC PGPV+ IQ KFR++EIPP ++ +HLGCIGGCD  L+ 
Sbjct: 668  NAIWLPGSILEAAVTSNICSSCNPGPVYLIQFKFRQIEIPPGFNANHLGCIGGCDDTLRQ 727

Query: 2158 LIEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXX 2337
            LIEICGTGSR    M+ARG+    T +  +R + R ++C HC+QTGHSSN+CPSQ     
Sbjct: 728  LIEICGTGSR----MSARGRGPTTTSSNGQRSSNRHNSCIHCQQTGHSSNDCPSQ---FS 780

Query: 2338 XXXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDLA 2517
                        N    ++C +CG  C +RTA T +NRGRKFYSC ++EC FF+WED ++
Sbjct: 781  RSRNSQSHTNSENGDPSVSCSTCGMPCVLRTANTANNRGRKFYSCPSQECNFFIWEDGVS 840


>ref|XP_017629354.1| PREDICTED: DNA topoisomerase 3-alpha [Gossypium arboreum]
          Length = 909

 Score = 1198 bits (3100), Expect = 0.0
 Identities = 573/840 (68%), Positives = 674/840 (80%), Gaps = 1/840 (0%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK +S IL               YNR+FEF Y++R QPCHM+FTSVTGHLME
Sbjct: 9    NVAEKPSVAKSVSGILSRNQGLRVRDGRSR-YNRLFEFNYSIRGQPCHMLFTSVTGHLME 67

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+FE+R+RKWHSCDP +LY AP++KFVP+DKLDI+RTLEEEAR+CQWLVLWLD D EGEN
Sbjct: 68   LEFEDRFRKWHSCDPLDLYHAPVRKFVPEDKLDIKRTLEEEARRCQWLVLWLDCDREGEN 127

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEVI+VC AVNRH+TI RA FS++ +R+I+ ++Q+L  PN   +D+VDARQEIDLRIG
Sbjct: 128  IAFEVIDVCRAVNRHLTIRRARFSALIDREIHHAMQNLIDPNPWFSDAVDARQEIDLRIG 187

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+D FV+D A DDR++VLSYGPCQFPTLGFVVERYWE+QSHEPEEFW I 
Sbjct: 188  ASFTRFQTMLLRDKFVIDSATDDRNLVLSYGPCQFPTLGFVVERYWEVQSHEPEEFWTIN 247

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH+SDEG ATF W R  L+D++CA I+YEMCV+EPTATV  V HKE+LKYPPYPL+T+E
Sbjct: 248  CSHRSDEGVATFNWMRGHLFDYTCAVIVYEMCVQEPTATVTKVQHKEKLKYPPYPLNTIE 307

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            L+KRASR  RMSS+HTMKVAEELY SGFISYPRTETD FS   DL  IV+EQ  HP WGS
Sbjct: 308  LEKRASRYFRMSSEHTMKVAEELYQSGFISYPRTETDCFSSRTDLHAIVQEQQEHPDWGS 367

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLD E  LWRNPG+GGHDDKAHPPIHPTKFS GE GWS+DH  LYELVVRHFLACV
Sbjct: 368  YAQRLLDLETGLWRNPGSGGHDDKAHPPIHPTKFSTGEHGWSQDHRTLYELVVRHFLACV 427

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA TTV+IDIAGE FSASG VI+ERNYLDVY Y+SW GS+IPTY +GQQF PT+L
Sbjct: 428  SQPAVGAETTVEIDIAGELFSASGRVILERNYLDVYRYESWGGSMIPTYTVGQQFAPTSL 487

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L++GVTRPPSLL+E +L+S M KAGIGTDAT  DHIKKLLDR+YATKDS ++FSPTNLG
Sbjct: 488  TLDTGVTRPPSLLSEADLLSCMDKAGIGTDATMHDHIKKLLDRFYATKDSNTRFSPTNLG 547

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYDDMGYELWKP LR+ ME DMK+VS G K K + LA+CLQ++K  F DAR  KV
Sbjct: 548  EALVMGYDDMGYELWKPNLRSMMEFDMKEVSVGNKSKDEVLATCLQQMKACFFDARLNKV 607

Query: 1801 NLLEAMELFFERSNRPV-GDGQNAGEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCR 1977
             LLEAM +FFERSNR V GD   AGEVVR C+ C ES MVLK+  +G+FM GC  FP CR
Sbjct: 608  KLLEAMAVFFERSNRAVGGDNYAAGEVVRQCDLCQESSMVLKKNRDGNFMVGCSGFPQCR 667

Query: 1978 NVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKD 2157
            N +WLPG+I EA+VT+N+CSSC PGPV+ IQ KFR++EIPP ++ +HLGCIGGCD  L+ 
Sbjct: 668  NAIWLPGSILEAAVTSNICSSCNPGPVYLIQFKFRQIEIPPGFNANHLGCIGGCDDTLRQ 727

Query: 2158 LIEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXX 2337
            LIEICGTGSR    M+ARG+    T +  +R + R + C HC+QTGHSSN+CPSQ     
Sbjct: 728  LIEICGTGSR----MSARGRGPTTTSSNGQRSSNRHNACIHCQQTGHSSNDCPSQ---FS 780

Query: 2338 XXXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDLA 2517
                        N    ++C +CG  C +RTA T +NRGRKFYSC ++EC FF+WED ++
Sbjct: 781  RSRNSQSHTNSQNGEPSVSCSTCGMPCVLRTANTANNRGRKFYSCPSQECNFFIWEDGVS 840


>ref|XP_024184593.1| DNA topoisomerase 3-alpha isoform X1 [Rosa chinensis]
          Length = 909

 Score = 1197 bits (3097), Expect = 0.0
 Identities = 571/840 (67%), Positives = 671/840 (79%), Gaps = 1/840 (0%)
 Frame = +1

Query: 1    NVAEKPSVAKGISTILXXXXXXXXXXXXXXXYNRIFEFEYTLRSQPCHMIFTSVTGHLME 180
            NVAEKPSVAK ++ IL               YN+I+EF Y++   PC M+FTSVTGHLME
Sbjct: 9    NVAEKPSVAKSVANILSRGQGLRMREGRSR-YNKIYEFNYSINGCPCQMLFTSVTGHLME 67

Query: 181  LDFEERYRKWHSCDPAELYAAPLKKFVPQDKLDIRRTLEEEARKCQWLVLWLDGDSEGEN 360
            L+FE+RYRKWHSCDP  L+ AP++KFVP+DKLDI+RTLEEEAR CQWLVLWLD D EGEN
Sbjct: 68   LEFEDRYRKWHSCDPVLLFQAPVRKFVPEDKLDIKRTLEEEARMCQWLVLWLDCDREGEN 127

Query: 361  IAFEVIEVCTAVNRHITIWRALFSSVTERDIYTSVQDLRQPNKLLADSVDARQEIDLRIG 540
            IAFEVI+VCT+VNRH+TI RA FS++ +RDI+ +VQ+L   NK  AD+VDARQEIDLRIG
Sbjct: 128  IAFEVIDVCTSVNRHLTIKRARFSALIDRDIHRAVQNLDNANKYFADAVDARQEIDLRIG 187

Query: 541  ASFTRFQTMLLKDAFVLDFAGDDRSVVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWKIT 720
            ASFTRFQTMLL+DAFV+D A DDR++VLSYGPCQFPTLGF+VERYWEIQSHEPEEFW I 
Sbjct: 188  ASFTRFQTMLLRDAFVIDSATDDRNLVLSYGPCQFPTLGFIVERYWEIQSHEPEEFWTIN 247

Query: 721  CSHKSDEGTATFEWKRERLYDHSCAGIIYEMCVEEPTATVKNVCHKERLKYPPYPLSTLE 900
            CSH+SDEG ATF W R   +DH+CA IIYEMCVE+PTATV  V  +E+LKYPPYPL+T+E
Sbjct: 248  CSHRSDEGIATFSWMRGHFFDHACAVIIYEMCVEDPTATVTKVRQQEKLKYPPYPLNTIE 307

Query: 901  LQKRASRCLRMSSDHTMKVAEELYMSGFISYPRTETDSFSGNNDLKGIVREQIGHPTWGS 1080
            L+KRASR  RMSS+HTMKVAEELY SGFISYPRTETD FS N DL  IV+EQ GHP WGS
Sbjct: 308  LEKRASRYFRMSSEHTMKVAEELYQSGFISYPRTETDGFSPNTDLHAIVQEQQGHPGWGS 367

Query: 1081 YAQQLLDPERRLWRNPGNGGHDDKAHPPIHPTKFSAGESGWSRDHNRLYELVVRHFLACV 1260
            YAQ+LLDP   LWRNP +GGHDDKAHPPIHPTKFS+GESGWS+DHNRLYELVVRHFLACV
Sbjct: 368  YAQRLLDPASGLWRNPSSGGHDDKAHPPIHPTKFSSGESGWSQDHNRLYELVVRHFLACV 427

Query: 1261 SQPAVGAGTTVDIDIAGEQFSASGCVIIERNYLDVYPYDSWDGSIIPTYVIGQQFLPTTL 1440
            SQPAVGA TTV+IDIAGE FSASG VI+ +NYLDVY ++SW GS++PTY +GQQF+PTTL
Sbjct: 428  SQPAVGAETTVEIDIAGEMFSASGRVILAKNYLDVYRFESWGGSLLPTYAVGQQFIPTTL 487

Query: 1441 KLESGVTRPPSLLTEVELISSMAKAGIGTDATTADHIKKLLDRYYATKDSRSQFSPTNLG 1620
             L+SGVTRPP LL+E +L+  M K GIGTDAT  DHIKKLLDR+YATKDS ++FSPTNLG
Sbjct: 488  TLDSGVTRPPPLLSEADLLGCMDKEGIGTDATMHDHIKKLLDRFYATKDSNTRFSPTNLG 547

Query: 1621 EALVMGYDDMGYELWKPYLRAKMEEDMKKVSTGTKRKSDFLASCLQEVKQVFLDARRQKV 1800
            EALVMGYDDMGY+LWKPYLRA ME DMK VS G K K++ L +CLQ++K  F+DAR  KV
Sbjct: 548  EALVMGYDDMGYKLWKPYLRAVMERDMKAVSEGNKSKAEVLETCLQQMKACFVDARLNKV 607

Query: 1801 NLLEAMELFFERSNRPVGDGQNA-GEVVRPCNACHESHMVLKRRLNGDFMAGCLNFPHCR 1977
             L EAM +FFERSNRP GD Q+A GE +R C  C E+ +VL++  +G+FMAGC+ +P CR
Sbjct: 608  KLFEAMGVFFERSNRPGGDEQHASGEFIRRCGHCQEADIVLRKNRDGNFMAGCMGYPQCR 667

Query: 1978 NVVWLPGAISEASVTTNVCSSCAPGPVFKIQLKFRRLEIPPNYDVDHLGCIGGCDSILKD 2157
            N +WLPG++SEA+VTTNVC+SC PGP++ IQ  FRRLEIPPNY  +HLGCIGGCD IL+ 
Sbjct: 668  NAIWLPGSVSEAAVTTNVCNSCTPGPIYLIQFTFRRLEIPPNYSTNHLGCIGGCDQILRQ 727

Query: 2158 LIEICGTGSRMATGMTARGQRAGETPNRTRRENPRQDTCAHCRQTGHSSNECPSQGFXXX 2337
            LIEICGTGSR A    ARG R   T +   R N RQ  C +C Q+GHSS +CPSQ     
Sbjct: 728  LIEICGTGSRSA----ARG-RGPATSSNVPRSNTRQGACIYCHQSGHSSGDCPSQSSGHR 782

Query: 2338 XXXXXXXXXXXXNNIGQIACESCGASCPVRTATTEHNRGRKFYSCQNRECGFFVWEDDLA 2517
                          I  ++C +CGA C +RTA T  NRGRKFYSC ++EC FFVWED+++
Sbjct: 783  SVRPRTMNAQSAGQI-SVSCNTCGAPCTLRTANTAQNRGRKFYSCPSQECNFFVWEDNVS 841