BLASTX nr result
ID: Mentha22_contig00018387
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Mentha22_contig00018387
(390 letters)
Database: ./nr
38,876,450 sequences; 13,856,398,315 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|EYU33651.1| hypothetical protein MIMGU_mgv1a001037mg [Mimulus... 175 5e-42
ref|XP_006346205.1| PREDICTED: uncharacterized protein LOC102606... 140 1e-31
ref|XP_004244107.1| PREDICTED: uncharacterized protein LOC101245... 139 3e-31
ref|XP_002277977.2| PREDICTED: uncharacterized protein LOC100267... 131 9e-29
emb|CBI26651.3| unnamed protein product [Vitis vinifera] 131 9e-29
emb|CAN63414.1| hypothetical protein VITISV_007685 [Vitis vinifera] 131 9e-29
gb|EPS73702.1| hypothetical protein M569_01052, partial [Genlise... 130 2e-28
ref|XP_002529909.1| bromodomain-containing protein [Ricinus comm... 129 4e-28
ref|XP_006475049.1| PREDICTED: uncharacterized protein LOC102624... 128 9e-28
ref|XP_006452393.1| hypothetical protein CICLE_v10007654mg [Citr... 128 9e-28
ref|XP_006452392.1| hypothetical protein CICLE_v10007654mg [Citr... 128 9e-28
dbj|BAB10577.1| unnamed protein product [Arabidopsis thaliana] 121 9e-26
ref|XP_004491407.1| PREDICTED: uncharacterized protein LOC101507... 121 9e-26
ref|NP_200315.2| DNA-binding bromodomain-containing protein [Ara... 121 9e-26
ref|XP_007020786.1| Bromodomain-containing protein, putative [Th... 120 2e-25
ref|XP_006279571.1| hypothetical protein CARUB_v10025841mg [Caps... 120 2e-25
ref|XP_002866072.1| hypothetical protein ARALYDRAFT_495586 [Arab... 120 3e-25
ref|XP_004165831.1| PREDICTED: uncharacterized protein LOC101229... 118 1e-24
ref|XP_004139866.1| PREDICTED: uncharacterized protein LOC101204... 118 1e-24
ref|XP_007142297.1| hypothetical protein PHAVU_008G268700g [Phas... 117 2e-24
>gb|EYU33651.1| hypothetical protein MIMGU_mgv1a001037mg [Mimulus guttatus]
Length = 907
Score = 175 bits (444), Expect = 5e-42
Identities = 86/137 (62%), Positives = 102/137 (74%), Gaps = 12/137 (8%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
ETK+L+PVGLYSDHSYARS+SRFAA +GSVAWKVAS RIEQALP GFKFGQGWVG+YEPL
Sbjct: 411 ETKELVPVGLYSDHSYARSMSRFAANIGSVAWKVASNRIEQALPEGFKFGQGWVGEYEPL 470
Query: 207 PTPVLMLENCRVKEPPFFTKVQHVVEQPRNFAKVIP------------GNLPFFDQRLPF 64
PTPVLML+NC VKEPP+ KVQ + PR F K +P ++PF +Q+LPF
Sbjct: 471 PTPVLMLQNCTVKEPPYLAKVQ---QNPRKFDKKVPTTLVSANKESPCSSVPFLEQKLPF 527
Query: 63 PGHAGIRSPAPITTTQP 13
G GI+ P P ++ P
Sbjct: 528 LGPTGIKPPPPPPSSSP 544
>ref|XP_006346205.1| PREDICTED: uncharacterized protein LOC102606294 [Solanum tuberosum]
Length = 929
Score = 140 bits (354), Expect = 1e-31
Identities = 71/121 (58%), Positives = 87/121 (71%), Gaps = 8/121 (6%)
Frame = -1
Query: 390 DETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEP 211
DE+K L+ VGLYSDH+YARSL+RFAATLG VAW+VAS++IEQALP GFKFG GWVG+YEP
Sbjct: 418 DESKHLVTVGLYSDHAYARSLTRFAATLGPVAWRVASQKIEQALPPGFKFGHGWVGEYEP 477
Query: 210 LPTPVLMLENCRVKEPPFFTKVQHVVEQPRN--------FAKVIPGNLPFFDQRLPFPGH 55
LPTPVL+LEN +KEPPFF+K H +N K P + P + + P+ G
Sbjct: 478 LPTPVLVLENYTLKEPPFFSKSVHTFGAQKNEKTSEDAIAPKDKPLSRPMLEGKSPYLGS 537
Query: 54 A 52
A
Sbjct: 538 A 538
>ref|XP_004244107.1| PREDICTED: uncharacterized protein LOC101245078 [Solanum
lycopersicum]
Length = 917
Score = 139 bits (351), Expect = 3e-31
Identities = 65/91 (71%), Positives = 78/91 (85%)
Frame = -1
Query: 390 DETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEP 211
DE+K L+ VGLYSDH+YARSL+RFAATLG VAW+VAS++IEQALP GFKFG+GWVG+YEP
Sbjct: 416 DESKHLVTVGLYSDHAYARSLARFAATLGPVAWRVASQKIEQALPPGFKFGRGWVGEYEP 475
Query: 210 LPTPVLMLENCRVKEPPFFTKVQHVVEQPRN 118
LPTPVL+LEN +KEPPFF+K H +N
Sbjct: 476 LPTPVLVLENYTLKEPPFFSKSVHKFGAQKN 506
>ref|XP_002277977.2| PREDICTED: uncharacterized protein LOC100267501 [Vitis vinifera]
Length = 898
Score = 131 bits (330), Expect = 9e-29
Identities = 72/145 (49%), Positives = 91/145 (62%), Gaps = 23/145 (15%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQL+ VGL++DHSYARSL+RFAATLG VAWKVAS+RIEQALP+G KFG+GWVG++EPL
Sbjct: 425 EAKQLVAVGLHADHSYARSLARFAATLGPVAWKVASQRIEQALPVGSKFGRGWVGEFEPL 484
Query: 207 PTPVLMLENCRVKEPPFFTKVQH--VVEQPRNFAK---------------------VIPG 97
PTPVLMLE KEP K+QH V+ + +K P
Sbjct: 485 PTPVLMLETRIQKEPFLVPKLQHNAVLRKDEKISKPPVPAKEHSVSGPTLEGKQSLFCPA 544
Query: 96 NLPFFDQRLPFPGHAGIRSPAPITT 22
+ P +++ P G AG +S P+ T
Sbjct: 545 SAPTTERKQPLFGSAGTKSTPPVNT 569
>emb|CBI26651.3| unnamed protein product [Vitis vinifera]
Length = 407
Score = 131 bits (330), Expect = 9e-29
Identities = 72/145 (49%), Positives = 91/145 (62%), Gaps = 23/145 (15%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQL+ VGL++DHSYARSL+RFAATLG VAWKVAS+RIEQALP+G KFG+GWVG++EPL
Sbjct: 124 EAKQLVAVGLHADHSYARSLARFAATLGPVAWKVASQRIEQALPVGSKFGRGWVGEFEPL 183
Query: 207 PTPVLMLENCRVKEPPFFTKVQH--VVEQPRNFAK---------------------VIPG 97
PTPVLMLE KEP K+QH V+ + +K P
Sbjct: 184 PTPVLMLETRIQKEPFLVPKLQHNAVLRKDEKISKPPVPAKEHSVSGPTLEGKQSLFCPA 243
Query: 96 NLPFFDQRLPFPGHAGIRSPAPITT 22
+ P +++ P G AG +S P+ T
Sbjct: 244 SAPTTERKQPLFGSAGTKSTPPVNT 268
>emb|CAN63414.1| hypothetical protein VITISV_007685 [Vitis vinifera]
Length = 923
Score = 131 bits (330), Expect = 9e-29
Identities = 72/145 (49%), Positives = 91/145 (62%), Gaps = 23/145 (15%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQL+ VGL++DHSYARSL+RFAATLG VAWKVAS+RIEQALP+G KFG+GWVG++EPL
Sbjct: 450 EAKQLVAVGLHADHSYARSLARFAATLGPVAWKVASQRIEQALPVGSKFGRGWVGEFEPL 509
Query: 207 PTPVLMLENCRVKEPPFFTKVQH--VVEQPRNFAK---------------------VIPG 97
PTPVLMLE KEP K+QH V+ + +K P
Sbjct: 510 PTPVLMLETRIQKEPFLVPKLQHNAVLRKDEKISKPPVPAKEHSVSGPTLEGKQSLFCPA 569
Query: 96 NLPFFDQRLPFPGHAGIRSPAPITT 22
+ P +++ P G AG +S P+ T
Sbjct: 570 SAPTTERKQPLFGSAGTKSTPPVNT 594
>gb|EPS73702.1| hypothetical protein M569_01052, partial [Genlisea aurea]
Length = 467
Score = 130 bits (327), Expect = 2e-28
Identities = 59/76 (77%), Positives = 69/76 (90%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E+KQL+PVGLYSDHSYARSL+ FAATLGSVAW++ SKRIEQALP GF +G+GWVGDYEPL
Sbjct: 392 ESKQLIPVGLYSDHSYARSLALFAATLGSVAWEITSKRIEQALPPGFNYGRGWVGDYEPL 451
Query: 207 PTPVLMLENCRVKEPP 160
PTP L+L+N +KEPP
Sbjct: 452 PTPALILKNRNIKEPP 467
>ref|XP_002529909.1| bromodomain-containing protein [Ricinus communis]
gi|223530586|gb|EEF32463.1| bromodomain-containing
protein [Ricinus communis]
Length = 933
Score = 129 bits (324), Expect = 4e-28
Identities = 61/86 (70%), Positives = 75/86 (87%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQL+ VGL++++SYARS++RFAATLG VAWKVAS+RIE+ALP GFKFG+GWVG+YEPL
Sbjct: 462 EIKQLVAVGLHAEYSYARSMARFAATLGPVAWKVASQRIEKALPPGFKFGRGWVGEYEPL 521
Query: 207 PTPVLMLENCRVKEPPFFTKVQHVVE 130
PTPVLM+E KEP FFTK+Q V+
Sbjct: 522 PTPVLMVETRMQKEPLFFTKLQSAVD 547
>ref|XP_006475049.1| PREDICTED: uncharacterized protein LOC102624873 [Citrus sinensis]
Length = 887
Score = 128 bits (321), Expect = 9e-28
Identities = 60/86 (69%), Positives = 72/86 (83%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
ETK L+ VGL++++SYARSL+RFAATLG VAWKVAS+RIEQALP G KFG+GWVG+YEPL
Sbjct: 423 ETKHLVAVGLHAEYSYARSLARFAATLGPVAWKVASRRIEQALPAGCKFGRGWVGEYEPL 482
Query: 207 PTPVLMLENCRVKEPPFFTKVQHVVE 130
PTPVLMLE C KE F+K+Q +
Sbjct: 483 PTPVLMLETCTQKESALFSKLQSTAD 508
>ref|XP_006452393.1| hypothetical protein CICLE_v10007654mg [Citrus clementina]
gi|557555619|gb|ESR65633.1| hypothetical protein
CICLE_v10007654mg [Citrus clementina]
Length = 676
Score = 128 bits (321), Expect = 9e-28
Identities = 60/86 (69%), Positives = 72/86 (83%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
ETK L+ VGL++++SYARSL+RFAATLG VAWKVAS+RIEQALP G KFG+GWVG+YEPL
Sbjct: 212 ETKHLVAVGLHAEYSYARSLARFAATLGPVAWKVASRRIEQALPAGCKFGRGWVGEYEPL 271
Query: 207 PTPVLMLENCRVKEPPFFTKVQHVVE 130
PTPVLMLE C KE F+K+Q +
Sbjct: 272 PTPVLMLETCTQKESALFSKLQSTAD 297
>ref|XP_006452392.1| hypothetical protein CICLE_v10007654mg [Citrus clementina]
gi|557555618|gb|ESR65632.1| hypothetical protein
CICLE_v10007654mg [Citrus clementina]
Length = 661
Score = 128 bits (321), Expect = 9e-28
Identities = 60/86 (69%), Positives = 72/86 (83%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
ETK L+ VGL++++SYARSL+RFAATLG VAWKVAS+RIEQALP G KFG+GWVG+YEPL
Sbjct: 197 ETKHLVAVGLHAEYSYARSLARFAATLGPVAWKVASRRIEQALPAGCKFGRGWVGEYEPL 256
Query: 207 PTPVLMLENCRVKEPPFFTKVQHVVE 130
PTPVLMLE C KE F+K+Q +
Sbjct: 257 PTPVLMLETCTQKESALFSKLQSTAD 282
>dbj|BAB10577.1| unnamed protein product [Arabidopsis thaliana]
Length = 639
Score = 121 bits (304), Expect = 9e-26
Identities = 54/76 (71%), Positives = 65/76 (85%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQ + VGL+++H+Y RSL+RFAATLG VAWK+AS+RIEQALP FKFG+GWVG+YEPL
Sbjct: 147 EIKQFVAVGLHAEHAYGRSLARFAATLGPVAWKIASQRIEQALPADFKFGRGWVGEYEPL 206
Query: 207 PTPVLMLENCRVKEPP 160
PTPVL+ E C KEPP
Sbjct: 207 PTPVLLFETCTPKEPP 222
>ref|XP_004491407.1| PREDICTED: uncharacterized protein LOC101507780 [Cicer arietinum]
Length = 909
Score = 121 bits (304), Expect = 9e-26
Identities = 71/148 (47%), Positives = 89/148 (60%), Gaps = 23/148 (15%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQL+ VGL +++SYARSL+RFAATLG AW+VAS+RI+QALP KFG+GWVG+YEPL
Sbjct: 435 EIKQLVTVGLQAEYSYARSLARFAATLGPTAWRVASRRIQQALPSDCKFGRGWVGEYEPL 494
Query: 207 PTPVLMLENCRVKEPPFFTKVQ--------------------HVVEQPRNFAK---VIPG 97
PTPVLML+N K+P TK+Q H V +P K V PG
Sbjct: 495 PTPVLMLDNRVQKQPSLATKLQSTTKSTKVRKNGKNVESSLEHSVNEPMFEVKQPAVCPG 554
Query: 96 NLPFFDQRLPFPGHAGIRSPAPITTTQP 13
+ + + F G AG+R A I T P
Sbjct: 555 SGLTSEGKPSFFGSAGVRPNASINLTHP 582
>ref|NP_200315.2| DNA-binding bromodomain-containing protein [Arabidopsis thaliana]
gi|186532184|ref|NP_001119438.1| DNA-binding
bromodomain-containing protein [Arabidopsis thaliana]
gi|18377658|gb|AAL66979.1| unknown protein [Arabidopsis
thaliana] gi|20465577|gb|AAM20271.1| unknown protein
[Arabidopsis thaliana] gi|332009188|gb|AED96571.1|
DNA-binding bromodomain-containing protein [Arabidopsis
thaliana] gi|332009189|gb|AED96572.1| DNA-binding
bromodomain-containing protein [Arabidopsis thaliana]
Length = 916
Score = 121 bits (304), Expect = 9e-26
Identities = 54/76 (71%), Positives = 65/76 (85%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQ + VGL+++H+Y RSL+RFAATLG VAWK+AS+RIEQALP FKFG+GWVG+YEPL
Sbjct: 424 EIKQFVAVGLHAEHAYGRSLARFAATLGPVAWKIASQRIEQALPADFKFGRGWVGEYEPL 483
Query: 207 PTPVLMLENCRVKEPP 160
PTPVL+ E C KEPP
Sbjct: 484 PTPVLLFETCTPKEPP 499
>ref|XP_007020786.1| Bromodomain-containing protein, putative [Theobroma cacao]
gi|508720414|gb|EOY12311.1| Bromodomain-containing
protein, putative [Theobroma cacao]
Length = 921
Score = 120 bits (302), Expect = 2e-25
Identities = 58/74 (78%), Positives = 66/74 (89%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQL+ VGL ++ SYARSL+RFAATLG VAWKVAS+RIEQALP+GFKFG+GWVG+YEPL
Sbjct: 433 EIKQLLVVGLQAEFSYARSLARFAATLGPVAWKVASRRIEQALPMGFKFGRGWVGEYEPL 492
Query: 207 PTPVLMLENCRVKE 166
PTPVLMLEN KE
Sbjct: 493 PTPVLMLENHAPKE 506
>ref|XP_006279571.1| hypothetical protein CARUB_v10025841mg [Capsella rubella]
gi|482548275|gb|EOA12469.1| hypothetical protein
CARUB_v10025841mg [Capsella rubella]
Length = 924
Score = 120 bits (302), Expect = 2e-25
Identities = 57/92 (61%), Positives = 72/92 (78%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQ + VGL+++H+Y RSL+RFAATLG VAWK+AS+RI+QALP FKFG+GWVG+YEPL
Sbjct: 430 EIKQFVAVGLHAEHAYGRSLARFAATLGPVAWKIASQRIKQALPADFKFGRGWVGEYEPL 489
Query: 207 PTPVLMLENCRVKEPPFFTKVQHVVEQPRNFA 112
PTPVL+ E C KEPP K V +P++ A
Sbjct: 490 PTPVLLFETCTPKEPP---KEASVFSKPKSKA 518
>ref|XP_002866072.1| hypothetical protein ARALYDRAFT_495586 [Arabidopsis lyrata subsp.
lyrata] gi|297311907|gb|EFH42331.1| hypothetical protein
ARALYDRAFT_495586 [Arabidopsis lyrata subsp. lyrata]
Length = 915
Score = 120 bits (300), Expect = 3e-25
Identities = 67/130 (51%), Positives = 83/130 (63%), Gaps = 14/130 (10%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQ + VGL+++H+Y RSL+RFAATLG VAWK+AS+RIEQALP FKFG+GWVG+YEPL
Sbjct: 423 EIKQFVAVGLHAEHAYGRSLARFAATLGPVAWKIASQRIEQALPADFKFGRGWVGEYEPL 482
Query: 207 PTPVLMLENCRVKEPP----FFTKVQHVVEQPRN---FAKVIP-----GNLPFFD--QRL 70
PTPVL+ E KEPP F+K + +N F +P GN P D +
Sbjct: 483 PTPVLLFETYTPKEPPKEASVFSKPKSNAAAKKNETLFKTPLPVKEQQGNRPVRDGNRAF 542
Query: 69 PFPGHAGIRS 40
PFP G S
Sbjct: 543 PFPTSIGASS 552
>ref|XP_004165831.1| PREDICTED: uncharacterized protein LOC101229993 [Cucumis sativus]
Length = 881
Score = 118 bits (295), Expect = 1e-24
Identities = 61/110 (55%), Positives = 77/110 (70%)
Frame = -1
Query: 390 DETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEP 211
DE +Q + VGL++++SYARSL+RFAATLG +AWKVAS+RIEQA+P+G KFG+GWVG+YEP
Sbjct: 423 DEIRQFVAVGLHAEYSYARSLARFAATLGPIAWKVASQRIEQAVPVGCKFGRGWVGEYEP 482
Query: 210 LPTPVLMLENCRVKEPPFFTKVQHVVEQPRNFAKVIPGNLPFFDQRLPFP 61
LPTPVL+ EN KEP + H R AK LP + L P
Sbjct: 483 LPTPVLIFENQNQKEPGLNNNL-HSTSALRKDAKPSDTPLPKQEHSLSAP 531
>ref|XP_004139866.1| PREDICTED: uncharacterized protein LOC101204699 [Cucumis sativus]
Length = 903
Score = 118 bits (295), Expect = 1e-24
Identities = 61/110 (55%), Positives = 77/110 (70%)
Frame = -1
Query: 390 DETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEP 211
DE +Q + VGL++++SYARSL+RFAATLG +AWKVAS+RIEQA+P+G KFG+GWVG+YEP
Sbjct: 445 DEIRQFVAVGLHAEYSYARSLARFAATLGPIAWKVASQRIEQAVPVGCKFGRGWVGEYEP 504
Query: 210 LPTPVLMLENCRVKEPPFFTKVQHVVEQPRNFAKVIPGNLPFFDQRLPFP 61
LPTPVL+ EN KEP + H R AK LP + L P
Sbjct: 505 LPTPVLIFENQNQKEPGLNNNL-HSTSALRKDAKPSDTPLPKQEHSLSAP 553
>ref|XP_007142297.1| hypothetical protein PHAVU_008G268700g [Phaseolus vulgaris]
gi|561015430|gb|ESW14291.1| hypothetical protein
PHAVU_008G268700g [Phaseolus vulgaris]
Length = 888
Score = 117 bits (292), Expect = 2e-24
Identities = 55/86 (63%), Positives = 67/86 (77%)
Frame = -1
Query: 387 ETKQLMPVGLYSDHSYARSLSRFAATLGSVAWKVASKRIEQALPLGFKFGQGWVGDYEPL 208
E KQL+ VGL ++HSYARSL+RFAATLG AWK+AS+RI+ ALP G KFG GWVG+YEPL
Sbjct: 413 EVKQLVTVGLQAEHSYARSLARFAATLGPTAWKIASQRIQHALPPGCKFGPGWVGEYEPL 472
Query: 207 PTPVLMLENCRVKEPPFFTKVQHVVE 130
PTPVL L+N ++P TK+Q E
Sbjct: 473 PTPVLKLDNLAQQQPSLGTKLQSTAE 498