BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Glycyrrhiza28_contig00026462
         (304 letters)

Database: ./nr 
           115,041,592 sequences; 42,171,959,267 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_012568718.1 PREDICTED: histidine kinase 2 isoform X1 [Cicer a...   187   3e-53
XP_004491583.1 PREDICTED: histidine kinase 2 isoform X2 [Cicer a...   187   3e-53
AHY24023.1 histidine kinase 2 [Lotus japonicus]                       184   6e-52
XP_015972862.1 PREDICTED: histidine kinase 2 [Arachis duranensis]     177   2e-49
XP_016165828.1 PREDICTED: histidine kinase 2 isoform X1 [Arachis...   176   4e-49
XP_016165829.1 PREDICTED: histidine kinase 2 isoform X2 [Arachis...   176   4e-49
XP_003545073.1 PREDICTED: histidine kinase 2-like [Glycine max] ...   171   1e-47
XP_019456911.1 PREDICTED: histidine kinase 2 isoform X5 [Lupinus...   164   5e-45
XP_019456909.1 PREDICTED: histidine kinase 2 isoform X3 [Lupinus...   164   5e-45
XP_019456910.1 PREDICTED: histidine kinase 2 isoform X4 [Lupinus...   164   5e-45
XP_019456907.1 PREDICTED: histidine kinase 2 isoform X1 [Lupinus...   164   5e-45
OIW04277.1 hypothetical protein TanjilG_00837 [Lupinus angustifo...   164   5e-45
XP_014626423.1 PREDICTED: histidine kinase 2-like isoform X3 [Gl...   164   7e-45
XP_014626422.1 PREDICTED: histidine kinase 2-like isoform X2 [Gl...   164   7e-45
XP_006575738.1 PREDICTED: histidine kinase 2-like isoform X1 [Gl...   164   7e-45
KHN43950.1 Histidine kinase 2, partial [Glycine soja]                 164   7e-45
XP_003617960.1 cytokinin receptor histidine kinase [Medicago tru...   160   2e-43
BAT80518.1 hypothetical protein VIGAN_03010800 [Vigna angularis ...   159   3e-43
XP_017430191.1 PREDICTED: histidine kinase 2 [Vigna angularis]        159   3e-43
KOM46329.1 hypothetical protein LR48_Vigan07g003300 [Vigna angul...   159   3e-43

>XP_012568718.1 PREDICTED: histidine kinase 2 isoform X1 [Cicer arietinum]
            XP_012568719.1 PREDICTED: histidine kinase 2 isoform X1
            [Cicer arietinum]
          Length = 1225

 Score =  187 bits (476), Expect = 3e-53
 Identities = 90/100 (90%), Positives = 94/100 (94%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            FTHDKGHVFVSIHLANEV+NPLH+MDAVLREGLN++ DISERT NTLSGFPVGNRWKSW 
Sbjct: 753  FTHDKGHVFVSIHLANEVKNPLHVMDAVLREGLNMNQDISERTCNTLSGFPVGNRWKSWE 812

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NFK LNSIN MDEPETIQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 813  NFKKLNSINLMDEPETIQLLVTVEDTGIGIPNDAQSRIFT 852


>XP_004491583.1 PREDICTED: histidine kinase 2 isoform X2 [Cicer arietinum]
          Length = 1204

 Score =  187 bits (476), Expect = 3e-53
 Identities = 90/100 (90%), Positives = 94/100 (94%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            FTHDKGHVFVSIHLANEV+NPLH+MDAVLREGLN++ DISERT NTLSGFPVGNRWKSW 
Sbjct: 732  FTHDKGHVFVSIHLANEVKNPLHVMDAVLREGLNMNQDISERTCNTLSGFPVGNRWKSWE 791

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NFK LNSIN MDEPETIQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 792  NFKKLNSINLMDEPETIQLLVTVEDTGIGIPNDAQSRIFT 831


>AHY24023.1 histidine kinase 2 [Lotus japonicus]
          Length = 1226

 Score =  184 bits (466), Expect = 6e-52
 Identities = 86/100 (86%), Positives = 94/100 (94%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            FTHDKGHVFVSIHLANEV+NPLHIMDAVLREG+NL+ D+S++TYNTLSGFPVGNRWKSWA
Sbjct: 754  FTHDKGHVFVSIHLANEVKNPLHIMDAVLREGVNLNQDLSDKTYNTLSGFPVGNRWKSWA 813

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
             F+ LNS+N MDEPE IQLLVTVEDTGIGIPTD QSRIFT
Sbjct: 814  TFRKLNSLNLMDEPEMIQLLVTVEDTGIGIPTDVQSRIFT 853


>XP_015972862.1 PREDICTED: histidine kinase 2 [Arachis duranensis]
          Length = 1236

 Score =  177 bits (448), Expect = 2e-49
 Identities = 85/100 (85%), Positives = 91/100 (91%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            FTHDKGHVFVSIHLANEV+NPLH MDAVLREGL LD D+S+ TYNTLSGF VGNRWKSWA
Sbjct: 765  FTHDKGHVFVSIHLANEVKNPLHSMDAVLREGLELDHDLSDNTYNTLSGFAVGNRWKSWA 824

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NFK LNS++ M+EPE IQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 825  NFKKLNSMDLMEEPELIQLLVTVEDTGIGIPIDAQSRIFT 864


>XP_016165828.1 PREDICTED: histidine kinase 2 isoform X1 [Arachis ipaensis]
          Length = 1236

 Score =  176 bits (445), Expect = 4e-49
 Identities = 84/100 (84%), Positives = 91/100 (91%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            FTHDKGHVFVS+HLANEV+NPLH MDAVLREGL LD D+S+ TYNTLSGF VGNRWKSWA
Sbjct: 765  FTHDKGHVFVSVHLANEVKNPLHGMDAVLREGLKLDHDLSDNTYNTLSGFAVGNRWKSWA 824

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NFK LNS++ M+EPE IQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 825  NFKKLNSMDLMEEPELIQLLVTVEDTGIGIPIDAQSRIFT 864


>XP_016165829.1 PREDICTED: histidine kinase 2 isoform X2 [Arachis ipaensis]
          Length = 1144

 Score =  176 bits (445), Expect = 4e-49
 Identities = 84/100 (84%), Positives = 91/100 (91%)
 Frame = +3

Query: 3   FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
           FTHDKGHVFVS+HLANEV+NPLH MDAVLREGL LD D+S+ TYNTLSGF VGNRWKSWA
Sbjct: 673 FTHDKGHVFVSVHLANEVKNPLHGMDAVLREGLKLDHDLSDNTYNTLSGFAVGNRWKSWA 732

Query: 183 NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
           NFK LNS++ M+EPE IQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 733 NFKKLNSMDLMEEPELIQLLVTVEDTGIGIPIDAQSRIFT 772


>XP_003545073.1 PREDICTED: histidine kinase 2-like [Glycine max] KRH14106.1
            hypothetical protein GLYMA_14G007100 [Glycine max]
            KRH14107.1 hypothetical protein GLYMA_14G007100 [Glycine
            max]
          Length = 1225

 Score =  171 bits (434), Expect = 1e-47
 Identities = 85/100 (85%), Positives = 90/100 (90%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            FTHDKGHVFVS+HLANEV+NPLHIMDAVLREGLNL+ DIS RTY+TLSGFPV NRWKSWA
Sbjct: 758  FTHDKGHVFVSVHLANEVKNPLHIMDAVLREGLNLNQDISNRTYDTLSGFPVCNRWKSWA 817

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NFK L+ IN   EPE IQLLV VEDTGIGIPTDAQSRIFT
Sbjct: 818  NFKQLSGIN---EPEIIQLLVIVEDTGIGIPTDAQSRIFT 854


>XP_019456911.1 PREDICTED: histidine kinase 2 isoform X5 [Lupinus angustifolius]
           XP_019456913.1 PREDICTED: histidine kinase 2 isoform X6
           [Lupinus angustifolius]
          Length = 1050

 Score =  164 bits (415), Expect = 5e-45
 Identities = 79/100 (79%), Positives = 89/100 (89%)
 Frame = +3

Query: 3   FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
           FT+DKGHV VS+HLANEV+NPL IMDAVLREGLNLD D+S+RTYNTLSGFP+  RWKSW 
Sbjct: 580 FTNDKGHVLVSVHLANEVKNPLDIMDAVLREGLNLDQDMSDRTYNTLSGFPIDERWKSWE 639

Query: 183 NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
           NFK L S+N+ D+P+ IQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 640 NFKMLGSLNT-DDPDMIQLLVTVEDTGIGIPMDAQSRIFT 678


>XP_019456909.1 PREDICTED: histidine kinase 2 isoform X3 [Lupinus angustifolius]
          Length = 1061

 Score =  164 bits (415), Expect = 5e-45
 Identities = 79/100 (79%), Positives = 89/100 (89%)
 Frame = +3

Query: 3   FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
           FT+DKGHV VS+HLANEV+NPL IMDAVLREGLNLD D+S+RTYNTLSGFP+  RWKSW 
Sbjct: 671 FTNDKGHVLVSVHLANEVKNPLDIMDAVLREGLNLDQDMSDRTYNTLSGFPIDERWKSWE 730

Query: 183 NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
           NFK L S+N+ D+P+ IQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 731 NFKMLGSLNT-DDPDMIQLLVTVEDTGIGIPMDAQSRIFT 769


>XP_019456910.1 PREDICTED: histidine kinase 2 isoform X4 [Lupinus angustifolius]
          Length = 1061

 Score =  164 bits (415), Expect = 5e-45
 Identities = 79/100 (79%), Positives = 89/100 (89%)
 Frame = +3

Query: 3   FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
           FT+DKGHV VS+HLANEV+NPL IMDAVLREGLNLD D+S+RTYNTLSGFP+  RWKSW 
Sbjct: 671 FTNDKGHVLVSVHLANEVKNPLDIMDAVLREGLNLDQDMSDRTYNTLSGFPIDERWKSWE 730

Query: 183 NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
           NFK L S+N+ D+P+ IQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 731 NFKMLGSLNT-DDPDMIQLLVTVEDTGIGIPMDAQSRIFT 769


>XP_019456907.1 PREDICTED: histidine kinase 2 isoform X1 [Lupinus angustifolius]
           XP_019456908.1 PREDICTED: histidine kinase 2 isoform X2
           [Lupinus angustifolius]
          Length = 1141

 Score =  164 bits (415), Expect = 5e-45
 Identities = 79/100 (79%), Positives = 89/100 (89%)
 Frame = +3

Query: 3   FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
           FT+DKGHV VS+HLANEV+NPL IMDAVLREGLNLD D+S+RTYNTLSGFP+  RWKSW 
Sbjct: 671 FTNDKGHVLVSVHLANEVKNPLDIMDAVLREGLNLDQDMSDRTYNTLSGFPIDERWKSWE 730

Query: 183 NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
           NFK L S+N+ D+P+ IQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 731 NFKMLGSLNT-DDPDMIQLLVTVEDTGIGIPMDAQSRIFT 769


>OIW04277.1 hypothetical protein TanjilG_00837 [Lupinus angustifolius]
          Length = 1339

 Score =  164 bits (415), Expect = 5e-45
 Identities = 79/100 (79%), Positives = 89/100 (89%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            FT+DKGHV VS+HLANEV+NPL IMDAVLREGLNLD D+S+RTYNTLSGFP+  RWKSW 
Sbjct: 869  FTNDKGHVLVSVHLANEVKNPLDIMDAVLREGLNLDQDMSDRTYNTLSGFPIDERWKSWE 928

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NFK L S+N+ D+P+ IQLLVTVEDTGIGIP DAQSRIFT
Sbjct: 929  NFKMLGSLNT-DDPDMIQLLVTVEDTGIGIPMDAQSRIFT 967


>XP_014626423.1 PREDICTED: histidine kinase 2-like isoform X3 [Glycine max]
          Length = 993

 Score =  164 bits (414), Expect = 7e-45
 Identities = 81/100 (81%), Positives = 87/100 (87%)
 Frame = +3

Query: 3   FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
           FTHDKGHVFVS+HLA+EV+NPLHIMDAVLREGLNL  DI+ RTY+TLSGFPV NRWKSWA
Sbjct: 529 FTHDKGHVFVSVHLASEVKNPLHIMDAVLREGLNLSQDITNRTYDTLSGFPVCNRWKSWA 588

Query: 183 NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
           NF  L+  N   EPE IQLLV VEDTGIGIPTDAQSRIFT
Sbjct: 589 NFTKLSGTN---EPEIIQLLVIVEDTGIGIPTDAQSRIFT 625


>XP_014626422.1 PREDICTED: histidine kinase 2-like isoform X2 [Glycine max]
          Length = 1130

 Score =  164 bits (414), Expect = 7e-45
 Identities = 81/100 (81%), Positives = 87/100 (87%)
 Frame = +3

Query: 3   FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
           FTHDKGHVFVS+HLA+EV+NPLHIMDAVLREGLNL  DI+ RTY+TLSGFPV NRWKSWA
Sbjct: 666 FTHDKGHVFVSVHLASEVKNPLHIMDAVLREGLNLSQDITNRTYDTLSGFPVCNRWKSWA 725

Query: 183 NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
           NF  L+  N   EPE IQLLV VEDTGIGIPTDAQSRIFT
Sbjct: 726 NFTKLSGTN---EPEIIQLLVIVEDTGIGIPTDAQSRIFT 762


>XP_006575738.1 PREDICTED: histidine kinase 2-like isoform X1 [Glycine max]
            XP_006575739.1 PREDICTED: histidine kinase 2-like isoform
            X1 [Glycine max] XP_006575740.1 PREDICTED: histidine
            kinase 2-like isoform X1 [Glycine max] XP_014626420.1
            PREDICTED: histidine kinase 2-like isoform X1 [Glycine
            max] KRH74010.1 hypothetical protein GLYMA_02G305900
            [Glycine max] KRH74011.1 hypothetical protein
            GLYMA_02G305900 [Glycine max] KRH74012.1 hypothetical
            protein GLYMA_02G305900 [Glycine max]
          Length = 1221

 Score =  164 bits (414), Expect = 7e-45
 Identities = 81/100 (81%), Positives = 87/100 (87%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            FTHDKGHVFVS+HLA+EV+NPLHIMDAVLREGLNL  DI+ RTY+TLSGFPV NRWKSWA
Sbjct: 757  FTHDKGHVFVSVHLASEVKNPLHIMDAVLREGLNLSQDITNRTYDTLSGFPVCNRWKSWA 816

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NF  L+  N   EPE IQLLV VEDTGIGIPTDAQSRIFT
Sbjct: 817  NFTKLSGTN---EPEIIQLLVIVEDTGIGIPTDAQSRIFT 853


>KHN43950.1 Histidine kinase 2, partial [Glycine soja]
          Length = 1224

 Score =  164 bits (414), Expect = 7e-45
 Identities = 81/100 (81%), Positives = 87/100 (87%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            FTHDKGHVFVS+HLA+EV+NPLHIMDAVLREGLNL  DI+ RTY+TLSGFPV NRWKSWA
Sbjct: 760  FTHDKGHVFVSVHLASEVKNPLHIMDAVLREGLNLSQDITNRTYDTLSGFPVCNRWKSWA 819

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NF  L+  N   EPE IQLLV VEDTGIGIPTDAQSRIFT
Sbjct: 820  NFTKLSGTN---EPEIIQLLVIVEDTGIGIPTDAQSRIFT 856


>XP_003617960.1 cytokinin receptor histidine kinase [Medicago truncatula] AET00919.1
            cytokinin receptor histidine kinase [Medicago truncatula]
          Length = 1269

 Score =  160 bits (404), Expect = 2e-43
 Identities = 81/100 (81%), Positives = 87/100 (87%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            F H+KGHVFVSIHLANEV+NPLHIMDAVLRE LNL+ D+SERT NTLSGFPVGNRWKSW 
Sbjct: 748  FIHNKGHVFVSIHLANEVKNPLHIMDAVLRECLNLNQDMSERTCNTLSGFPVGNRWKSWE 807

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
             F+ LN  +   E ETIQLLVTVEDTGIGIPTDAQSRIFT
Sbjct: 808  KFQKLNLAH---ESETIQLLVTVEDTGIGIPTDAQSRIFT 844


>BAT80518.1 hypothetical protein VIGAN_03010800 [Vigna angularis var. angularis]
          Length = 1159

 Score =  159 bits (402), Expect = 3e-43
 Identities = 75/100 (75%), Positives = 87/100 (87%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            F HDKGHVFVS+HLANEV+NPLH+MDAVL EGLN++ D+S RTY+TLSGFPV N+WKSWA
Sbjct: 723  FNHDKGHVFVSLHLANEVKNPLHVMDAVLSEGLNVNQDVSNRTYDTLSGFPVCNKWKSWA 782

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NF+ L+S+   D+PE  QLLV VEDTG GIPTDAQSRIFT
Sbjct: 783  NFEKLSSV---DDPENFQLLVIVEDTGTGIPTDAQSRIFT 819


>XP_017430191.1 PREDICTED: histidine kinase 2 [Vigna angularis]
          Length = 1190

 Score =  159 bits (402), Expect = 3e-43
 Identities = 75/100 (75%), Positives = 87/100 (87%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            F HDKGHVFVS+HLANEV+NPLH+MDAVL EGLN++ D+S RTY+TLSGFPV N+WKSWA
Sbjct: 723  FNHDKGHVFVSLHLANEVKNPLHVMDAVLSEGLNVNQDVSNRTYDTLSGFPVCNKWKSWA 782

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NF+ L+S+   D+PE  QLLV VEDTG GIPTDAQSRIFT
Sbjct: 783  NFEKLSSV---DDPENFQLLVIVEDTGTGIPTDAQSRIFT 819


>KOM46329.1 hypothetical protein LR48_Vigan07g003300 [Vigna angularis]
          Length = 1223

 Score =  159 bits (402), Expect = 3e-43
 Identities = 75/100 (75%), Positives = 87/100 (87%)
 Frame = +3

Query: 3    FTHDKGHVFVSIHLANEVRNPLHIMDAVLREGLNLDLDISERTYNTLSGFPVGNRWKSWA 182
            F HDKGHVFVS+HLANEV+NPLH+MDAVL EGLN++ D+S RTY+TLSGFPV N+WKSWA
Sbjct: 756  FNHDKGHVFVSLHLANEVKNPLHVMDAVLSEGLNVNQDVSNRTYDTLSGFPVCNKWKSWA 815

Query: 183  NFKTLNSINSMDEPETIQLLVTVEDTGIGIPTDAQSRIFT 302
            NF+ L+S+   D+PE  QLLV VEDTG GIPTDAQSRIFT
Sbjct: 816  NFEKLSSV---DDPENFQLLVIVEDTGTGIPTDAQSRIFT 852