BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Forsythia22_contig00010728
         (3314 letters)

Database: ./nr 
           69,698,275 sequences; 24,982,196,650 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011093631.1| PREDICTED: DNA topoisomerase 1-like [Sesamum...  1189   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                1132   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]              1129   0.0  
emb|CDP13767.1| unnamed protein product [Coffea canephora]           1117   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]      1101   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]               1093   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]            1085   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]            1083   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...  1082   0.0  
gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythra...  1079   0.0  
ref|XP_012845487.1| PREDICTED: DNA topoisomerase 1-like [Erythra...  1079   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                 1075   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]              1074   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                 1071   0.0  
dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]                1059   0.0  
ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo...  1058   0.0  
dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]                 1055   0.0  
dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]             1043   0.0  
ref|XP_009619726.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1041   0.0  
ref|XP_009790344.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1033   0.0  

>ref|XP_011093631.1| PREDICTED: DNA topoisomerase 1-like [Sesamum indicum]
          Length = 893

 Score = 1189 bits (3077), Expect = 0.0
 Identities = 620/895 (69%), Positives = 682/895 (76%), Gaps = 2/895 (0%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            E+C   K++DDMDEDDEPLVFKRS SS KQ+Q NS+TK  LS +K+D     P  D+  +
Sbjct: 4    ESCNDQKLMDDMDEDDEPLVFKRSSSSAKQSQGNSETKRPLS-QKHDRPLNRPSPDVRPQ 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + + +QK K  P  + P +                 ++     + +PST  TD+S  +
Sbjct: 63   NGQSTMIQKSKTVPSSRTPPLRSPLASPKSSNSSAKALAVRPREVDPRPSTSVTDESNSV 122

Query: 2736 NKQIEEEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANKGTLQLDT--KPS 2563
              QI++EKP T+     ++++EDSEDDKPLSAR P G SK  SN+ANKG   L +  K  
Sbjct: 123  KHQIKDEKPSTKATGGLNEDSEDSEDDKPLSARLPAGLSKVNSNHANKGPNALTSVQKTK 182

Query: 2562 IPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXXXXXXS 2383
            IPK EDSDDE PLSSKFQ                 E+KP++AK  +NG            
Sbjct: 183  IPKPEDSDDEIPLSSKFQVKSNAGESTNRP-SISGERKPLLAKYDQNGSASAERKPS--- 238

Query: 2382 TMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQITKKS 2203
            T+LKKRPA  +KS G S +KK KLS AS P  +K+ S K E K       +PISQ  K+ 
Sbjct: 239  TILKKRPADGVKSAGESYLKKPKLSDASTPNKTKETSIKDEMKDEDDEDHVPISQRIKQQ 298

Query: 2202 ATSDKKLSPVKKITKVVSTSLXXXXXXXXXXXKTSNYSKSSKVPPGSGEGQKWTTLIHNG 2023
             +SDKK S  K +TK +S S            K S YSKSSKVPP SGEGQKWTTL+HNG
Sbjct: 299  TSSDKKSSSAKNMTKPISASAKKTSKKPKKVMKNSKYSKSSKVPPSSGEGQKWTTLVHNG 358

Query: 2022 LIFPPPYKPHGVKMLYKGKPVDLTPEQEEAATMFAVMLDTDYMNKPKFKENFMNDWRKVL 1843
            +IFPPPYKPHGVKMLYKGKPVDLTPEQEE ATM+AVMLDTDYMNKPKFKENFM DWRK+L
Sbjct: 359  VIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMNKPKFKENFMADWRKIL 418

Query: 1842 GKKHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKE 1663
            GK H+IQ+LE CDFTPIYEWHQ                          KYMWAIVNGVKE
Sbjct: 419  GKNHVIQSLEHCDFTPIYEWHQKEKEKKKQMTAEEKKALKEEKLKQEEKYMWAIVNGVKE 478

Query: 1662 KVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGNDAQIPECPIPGESWKEIRHD 1483
            KVGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDITINIG DA IPECPIPGESWKEIRHD
Sbjct: 479  KVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWKEIRHD 538

Query: 1482 NTVTWLAFWNDPINPKEIKYVFLAASSTLKGQSDKEKYEKARLLKDYIQGIRAAYTKGFT 1303
            NTVTWLA+WNDPINPKE KYVFLAASSTLKGQSDKEKYEKARLLKDYI GIRAAYTK FT
Sbjct: 539  NTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFT 598

Query: 1302 SKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPLPPNSLKFDFLGK 1123
            +KD TKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+PPN LKFDFLGK
Sbjct: 599  NKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGK 658

Query: 1122 DSIRYQNEVEVEPAVFKAIQQFRSXXXXXXXXXXXXDTSKLNAHLKELMPGLTAKVFRTY 943
            DSIRYQNEVEVE  VFKAIQQFRS            DTSKLNAHLKELMPGLTAKVFRTY
Sbjct: 659  DSIRYQNEVEVETPVFKAIQQFRSGKKGSDDMFDRLDTSKLNAHLKELMPGLTAKVFRTY 718

Query: 942  NASITLDDMLSRETKGGDAAEKVVVYQHANKEVAIICNHQRTVSKSHSAQILRLNEKIEE 763
            NASITLDD LSRETKGGD AEKVVVYQHANKEVAIICNHQRTVSKSHSAQ+ RLNEKIEE
Sbjct: 719  NASITLDDKLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMTRLNEKIEE 778

Query: 762  LKGVLEELETDLVRAKKGKPPLKNTDGKPKRNMNPEALKRKIAQTNAKIEKMEREKESKE 583
            LKGVLEEL+TDL RAKKGKPPLK+ DGKPKRN+NP+AL++KIAQTNAKIEKMER+KE+KE
Sbjct: 779  LKGVLEELQTDLARAKKGKPPLKSADGKPKRNLNPDALEKKIAQTNAKIEKMERDKETKE 838

Query: 582  DLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWSMDVDPSFRF 418
            DLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKF W+MDVDPSFRF
Sbjct: 839  DLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPSFRF 893


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score = 1132 bits (2929), Expect = 0.0
 Identities = 610/918 (66%), Positives = 674/918 (73%), Gaps = 25/918 (2%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC  P + DDMDEDDEP+VFKR+ S+ KQ+Q NS+T++ +SS+K D +    + D    
Sbjct: 4    EACPTPNLRDDMDEDDEPIVFKRNNSASKQSQTNSETRK-VSSQKRDGQSVRQIYDSRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNT--------------- 2782
            N + S  QK +M PP K PS                   +  P                 
Sbjct: 63   NGESSSGQKGRMVPPSK-PSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPVSSLPA 121

Query: 2781 NSKPSTLATDKSKIINKQ-----IEEEK--PLTEPAAEPSDNTEDSEDDKPLSARHPVGF 2623
            NSKPST  + K K  N+      I+EEK  PL   +A  +D+ EDS+D KPLS RH    
Sbjct: 122  NSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDS-EDSDDGKPLSLRHSASS 180

Query: 2622 SKAKSNNANKGTLQLDTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPI 2443
            SK  +N  +K       + S P+ EDSDDEKPLSS+F            + D D++K P+
Sbjct: 181  SKGNTNQVSK-------EGSKPENEDSDDEKPLSSRFPLKSGVGESTSKAYDSDDDK-PL 232

Query: 2442 VAKIHKNGXXXXXXXXXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKA 2263
              K+  NG           S M  KRP  ++KS+   SVKK KLSS + P N KQ S K 
Sbjct: 233  AKKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKKQASVKP 292

Query: 2262 EPKAXXXXXD-LPISQITKKSATSDKKLSPVKKITKVVSTSLXXXXXXXXXXXKTSNYSK 2086
            EPKA     D LPISQ  KKS TS+ K S +KK TKVVS+S+           K S YSK
Sbjct: 293  EPKAEDDDDDHLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMKNSKYSK 352

Query: 2085 SSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEAATMFAVMLD 1906
            SSKVPP SGEG+KW  L HNG+IFPPPYKPHG+KMLYKGKPVDLTPEQEE ATMFAVMLD
Sbjct: 353  SSKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATMFAVMLD 412

Query: 1905 TDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXX 1726
            TDYMNKP+FKENF  DW+K+LGK H+IQNLE+CDF+PIYEWHQ                 
Sbjct: 413  TDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTTEEKKAL 472

Query: 1725 XXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIG 1546
                     KYMWA V+G KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI P DITINIG
Sbjct: 473  KEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCDITINIG 532

Query: 1545 NDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLKGQSDKEKYE 1366
             DA IPECP+PGE WKE+RHDNTVTWLAFWNDPINPKE KYVFLAASSTLKG SDKEKYE
Sbjct: 533  KDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLSDKEKYE 592

Query: 1365 KARLLKDYIQGIRAAYTKGFTSKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCT 1186
            KARLLKDYIQGIRAAYTK F SKD TKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCT
Sbjct: 593  KARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCT 652

Query: 1185 LKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXXXXXXXXXDTS 1006
            LKVENVEP+PPN LKFDFLGKDSIRYQNEVEVE AVFKAIQQFRS            DTS
Sbjct: 653  LKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLFDLLDTS 712

Query: 1005 KLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHANKEVAIICNH 826
            KLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGD AEKVVVYQHANKEVAIICNH
Sbjct: 713  KLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEVAIICNH 772

Query: 825  QRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPL--KNTDGKPKRNMNPEA 652
            QRTVSKSHSAQ+LRLNEKIEELK V+EEL++DL R KKGKPPL  KN DGKPKRN+NPE+
Sbjct: 773  QRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKRNLNPES 832

Query: 651  LKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 472
            L++KIAQTNAKIEKMER+KE+KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK
Sbjct: 833  LEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNK 892

Query: 471  SLLAKFTWSMDVDPSFRF 418
            SLLAKFTW+MDVDPSFRF
Sbjct: 893  SLLAKFTWAMDVDPSFRF 910


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1129 bits (2921), Expect = 0.0
 Identities = 607/913 (66%), Positives = 678/913 (74%), Gaps = 20/913 (2%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            +AC K KM+D++DEDDEPLVFKRS ++ K NQ NS TK+S  S++ D + G  VSD+ S 
Sbjct: 4    QACVKEKMMDEIDEDDEPLVFKRSNATSKHNQLNSDTKKS--SQRYDGQSGRQVSDVPST 61

Query: 2916 NEKISGVQKVK------MAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLAT 2755
            N + S   K K      M  P+ +P                       P  N K S+ + 
Sbjct: 62   NGQSSSASKGKTTKLSSMKSPIASPKASTSFAKAS-------------PVANPKVSSSSD 108

Query: 2754 DKSKIINKQ-----IEEEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANKG 2590
            D+SK  +KQ     ++EEK L  PAAEP     DSED+KPLSAR   G +K  SNNANKG
Sbjct: 109  DRSKHSSKQNTINVVKEEKELVNPAAEPYG---DSEDEKPLSARLFTGLTKGSSNNANKG 165

Query: 2589 TLQLDT------KPSIPKY-EDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKI 2431
             +          KP I +Y +DSDDE PLSSKF+           S + D+ K  +V+  
Sbjct: 166  LINSSPASLPVPKPEINRYSDDSDDEIPLSSKFRLKANAGTSTVKSYESDDNKT-LVSNF 224

Query: 2430 HKNGXXXXXXXXXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKA 2251
             +NG              + KRP  E+KS+  SSVKK KLS AS P+N+KQ S KAEPKA
Sbjct: 225  QQNGSINRGSKSSIK---VNKRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKA 281

Query: 2250 XXXXXD-LPISQITKKSATSDKKLSPVK-KITKVVSTSLXXXXXXXXXXXKTSNYSKSSK 2077
                 D +PISQ  KKSATS  K S  K K+TKVVS+S+           K S YSKSSK
Sbjct: 282  DDSDDDHVPISQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSKSSK 341

Query: 2076 VPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEAATMFAVMLDTDY 1897
            VPP SGEG+KW TL+HNG+IFPPPYKPHGVKMLYKGKPVDLTPEQEE ATMFAVMLDTDY
Sbjct: 342  VPPSSGEGKKWNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDY 401

Query: 1896 MNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXX 1717
            M K KFKENFM+DWRK+LGK H+IQNLEDCDFTPIYEWHQ                    
Sbjct: 402  MTKSKFKENFMDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEE 461

Query: 1716 XXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGNDA 1537
                  KYMWAIVNGVKEKVGNFRVEPP LFRGRGEHPKMGKLKK I PSDITINIG DA
Sbjct: 462  RLKQEEKYMWAIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDA 521

Query: 1536 QIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLKGQSDKEKYEKAR 1357
             IPECPIPGESWKEIRHDNTVTWLAFWNDPI P+E KYVFLAASS+LKGQSDKEKYEKAR
Sbjct: 522  PIPECPIPGESWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKAR 581

Query: 1356 LLKDYIQGIRAAYTKGFTSKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 1177
            LLKD+IQGIRAAYTK F SKD+TK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 582  LLKDFIQGIRAAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 641

Query: 1176 ENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXXXXXXXXXDTSKLN 997
            ENVEP PP+ LKFDFLGKDSIRYQNEVEVE  V+KAIQQFR+            DTSKLN
Sbjct: 642  ENVEPKPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLN 701

Query: 996  AHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHANKEVAIICNHQRT 817
            AHLK LMPGLTAKVFRTYNASITLD+MLSRETKGG+ AEK+VVYQHANKEVAIICNHQRT
Sbjct: 702  AHLKGLMPGLTAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRT 761

Query: 816  VSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKPKRNMNPEALKRKI 637
            VSKSH AQ+ RLN KI+ELKG+L+ L+TDL RAKKGKPPL++ DGKPKRN+ PEAL+RKI
Sbjct: 762  VSKSHPAQMTRLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKI 821

Query: 636  AQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAK 457
             QTNAKIEKMER+KE+KE LKT+ALGTSKI+YLDPRITVAWCKRHEVPIEK+FNKSLLAK
Sbjct: 822  GQTNAKIEKMERDKETKEGLKTIALGTSKISYLDPRITVAWCKRHEVPIEKVFNKSLLAK 881

Query: 456  FTWSMDVDPSFRF 418
            F WSMDVDPSFRF
Sbjct: 882  FAWSMDVDPSFRF 894


>emb|CDP13767.1| unnamed protein product [Coffea canephora]
          Length = 926

 Score = 1117 bits (2890), Expect = 0.0
 Identities = 600/925 (64%), Positives = 666/925 (72%), Gaps = 32/925 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC+ P +++D DE++ PLVFKR+ SS KQN  NS+TK+ LSS+K D +     SD+   
Sbjct: 4    EACSTPSLLEDSDEENAPLVFKRTSSSSKQNLSNSETKK-LSSQKRDGQSSRNSSDVCPV 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  Q  ++    K P                    +  P  NSKPS+  +   K +
Sbjct: 63   NGQSSSAQTGRVVSSAKTPPAKSPLSSPKAANISAKTSLITSPGANSKPSSSTSATVKQL 122

Query: 2736 ----NKQIEEEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANKGT--LQLD 2575
                N  + +    +  AA+ S   EDS+DDKPL A+ P G S+A  N+ NK      L 
Sbjct: 123  ENHKNSPVVKLPKRSVSAAKLSSTPEDSDDDKPLMAKLPSGSSRAIVNHGNKDGDGSSLV 182

Query: 2574 TKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXXX 2395
             KP + + EDSDDEKPLSS++            S +   EKK + AK+ +NG        
Sbjct: 183  QKPGVEEDEDSDDEKPLSSRYLSKSNLVESISKSRN-PGEKKSLPAKVQQNGSALRDGPV 241

Query: 2394 XXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDL----- 2230
               S++  KRP  E+KS+  S+VKK KLS  +  IN KQ + KAEPK      D+     
Sbjct: 242  GKSSSLSNKRPPGEVKSSDESAVKKPKLSGPTAAINKKQATLKAEPKVEDDDDDILISQT 301

Query: 2229 ---------------------PISQITKKSATSDKKLSPVKKITKVVSTSLXXXXXXXXX 2113
                                 PI+Q  KKS TS  + S VKK+ KVVS+SL         
Sbjct: 302  AKKMFASASKPKSNDDDDDHVPITQRMKKSTTSVSQSSSVKKVAKVVSSSLKKTNKKSKK 361

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K S YSKSSKVPPGSGEGQKWTTL+HNG+IFPPPYKPHGVKMLYKG+PV LTPEQEE 
Sbjct: 362  IIKKSKYSKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGQPVTLTPEQEEV 421

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFAVMLDTDYM+KP+FKENF +DW+++LGK H IQNLEDCDF PIYEWHQ        
Sbjct: 422  ATMFAVMLDTDYMSKPQFKENFFSDWKRILGKNHTIQNLEDCDFRPIYEWHQKEKEKKKQ 481

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 
Sbjct: 482  MTTEEKKSLKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 541

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKEIRHDNTVTWLAFWNDPINPKE KYVFLAASSTLK
Sbjct: 542  PRDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLK 601

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTSKDLTKKQIAVATYLIDKLALRAGNEKDDD 1213
            GQSDKEKYEKARLLKDYI GIR AYTK F SKD  KKQIAVATYLIDKLALRAGNEKDDD
Sbjct: 602  GQSDKEKYEKARLLKDYIHGIRTAYTKDFASKDPMKKQIAVATYLIDKLALRAGNEKDDD 661

Query: 1212 EADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXXX 1033
            EADTVGCCTLKVENVEP+PPN LKFDFLGKDSIRYQNEVEVE  VFKAIQQFRS      
Sbjct: 662  EADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVESGVFKAIQQFRSGKEGSE 721

Query: 1032 XXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHAN 853
                  DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSR+T GGD  EKVVVYQ AN
Sbjct: 722  DLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRKTNGGDVLEKVVVYQQAN 781

Query: 852  KEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKPK 673
            KEVAIICNHQRTVSK+HSAQ+ RLNEKIEELKGVLEEL+TDL RAKKGKPPLKN DGKPK
Sbjct: 782  KEVAIICNHQRTVSKTHSAQMSRLNEKIEELKGVLEELKTDLSRAKKGKPPLKNADGKPK 841

Query: 672  RNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEVP 493
            RN+NPEAL+RKIAQTNAKIEKMER+KE+KEDLKTVALGTSKINYLDPRITVAWCKRHEVP
Sbjct: 842  RNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVP 901

Query: 492  IEKIFNKSLLAKFTWSMDVDPSFRF 418
            IEKIFNKSLLAKF WSMDVDPSFRF
Sbjct: 902  IEKIFNKSLLAKFAWSMDVDPSFRF 926


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score = 1101 bits (2847), Expect = 0.0
 Identities = 595/926 (64%), Positives = 666/926 (71%), Gaps = 33/926 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC    +++DM++D  P++FKRS+ + KQNQ NS+ K+ LS +K D +     SD+   
Sbjct: 4    EACTT-NLMEDMEDDGGPVIFKRSKPAPKQNQANSE-KKKLSLQKQDGQSAVHTSDVRPA 61

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  K P V                  +  P  NSKPS  AT  +K  
Sbjct: 62   NGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAKQQ 121

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + PAA+ + N+E S+D+KPLSAR     SK KSN+ANK  G    
Sbjct: 122  NHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSCS 180

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P I + EDS+DEKPLS +F            S D DE KKP+ AK+ +NG       
Sbjct: 181  IRRPVIEESEDSEDEKPLSCRFTSKSSLGESTSKSYDSDE-KKPLAAKVQQNGSASRDGP 239

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++  KRP  E KS   SSVKK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 240  MNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 299

Query: 2217 ITKKS-------------------------ATSDKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS                         A+  K   PVKK + VVS+SL         
Sbjct: 300  RGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNKNSKK 359

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K + Y+KSSKVPPGSGEGQKWTTL+HNG+IFPPPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 360  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 419

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFAVMLDTDYMNKP FKENF +DW+K+LGK H+IQNLEDCDF PIYEWHQ        
Sbjct: 420  ATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKEKKKQ 479

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 
Sbjct: 480  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 539

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+ NTVTWLA+WNDPIN KE KYVFLAASSTLK
Sbjct: 540  PRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAASSTLK 599

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQIAVATYLIDKLALRAGNEKDD
Sbjct: 600  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 659

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTLKVENVEP+PPN LKFDFLGKDSIRYQNEV+VEPAVFKAIQQFRS     
Sbjct: 660  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 719

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ETKGG+ AE VVVYQHA
Sbjct: 720  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVVYQHA 779

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKPP K  DGK 
Sbjct: 780  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGADGKA 839

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPEAL+RKI QTNAKIEKMER+KE+KEDLKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 840  KRNLNPEALERKITQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 899

Query: 495  PIEKIFNKSLLAKFTWSMDVDPSFRF 418
            PIEKIFNKSLLAKF WSMDVDPSFRF
Sbjct: 900  PIEKIFNKSLLAKFAWSMDVDPSFRF 925


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score = 1093 bits (2828), Expect = 0.0
 Identities = 593/928 (63%), Positives = 667/928 (71%), Gaps = 35/928 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC  P +++DM++D+ P++FKRS  + KQNQ NS+ K+ LS +K+  +     SD+   
Sbjct: 4    EACT-PNLMEDMEDDEGPVIFKRSNPASKQNQANSE-KKKLSLQKHVGQSAVHTSDVRPA 61

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  K P V                  +  P  NSKPS  AT  +K  
Sbjct: 62   NGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAKQQ 121

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + PAA+ + N+E S+D+KPLSAR     SK KSN+ANK  G    
Sbjct: 122  NHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSCS 180

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +  I + EDS+DEKPLS +F            S D DE KKP+ AK+ +NG       
Sbjct: 181  IRRRVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDE-KKPLAAKVQQNGSVSRDGP 239

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEP--KAXXXXXDLPI 2224
                +++  KRP  E+KS   SSVKK KLSS    I++KQ + K EP  KA     ++P+
Sbjct: 240  MNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDDNIPL 299

Query: 2223 SQITKKS-------------------------ATSDKKLSPVKKITKVVSTSLXXXXXXX 2119
            SQ  KKS                         A+  K  +PVKK + VVS SL       
Sbjct: 300  SQRGKKSQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKNS 359

Query: 2118 XXXXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQE 1939
                K + Y+KSSKVPPGSGEGQKWTTL+HNG+IFPPPY PHGVKMLYK +P+ LTPEQE
Sbjct: 360  KKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLTPEQE 419

Query: 1938 EAATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXX 1759
            E ATMFAVMLDTDYMNKP+FKENF +DW+K+LGK H IQNLEDCDF PIYEWHQ      
Sbjct: 420  EVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKK 479

Query: 1758 XXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 1579
                                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR
Sbjct: 480  KQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKR 539

Query: 1578 ICPSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASST 1399
            I P DITINIG DA IPECPIPGE WKE+R+DNTVTWLAFW DPIN KE KYVFLAASST
Sbjct: 540  IRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLAASST 599

Query: 1398 LKGQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEK 1222
            LKGQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQIAVATYLIDKLALRAGNEK
Sbjct: 600  LKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEK 659

Query: 1221 DDDEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXX 1042
            DDDEADTVGCCTLKVENVEP+PPN LKFDFLGKDSIRYQNEV+VEPAVFKAIQQFRS   
Sbjct: 660  DDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKE 719

Query: 1041 XXXXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQ 862
                     DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ETKGG+ AEKVVVYQ
Sbjct: 720  GSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKVVVYQ 779

Query: 861  HANKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDG 682
            HANKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  +EEL+TDL R KKGKPP K  DG
Sbjct: 780  HANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSKGADG 839

Query: 681  KPKRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRH 502
            KPKRN+NPEAL+RK+AQ NAKIEKMER+KE+KEDLKTVALGTSKINYLDPRITVAWCKRH
Sbjct: 840  KPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRH 899

Query: 501  EVPIEKIFNKSLLAKFTWSMDVDPSFRF 418
            EVPIEKIFNKSLLAKF WSMDVDPSFRF
Sbjct: 900  EVPIEKIFNKSLLAKFAWSMDVDPSFRF 927


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score = 1085 bits (2805), Expect = 0.0
 Identities = 584/919 (63%), Positives = 660/919 (71%), Gaps = 33/919 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC    +++DM++D+ P++FKRS  + KQNQ NS+ K+ LS +K+  +     SD+   
Sbjct: 4    EACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSE-KKKLSLQKHVGQSAVHTSDVRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  K P V                  +  P  NSKPS  AT  +K  
Sbjct: 63   NGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATSTAKQQ 122

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + PAA+ + N+E S+D+KPLSAR     SK KSN+ANK  G    
Sbjct: 123  NHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSCS 181

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P I + EDS+DEKPLS +F            S D DE KKP+ AK+  NG       
Sbjct: 182  IRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDE-KKPLAAKVQPNGSASRDSP 240

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++  KRP  E+KS   SS+KK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 241  MNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2217 ITKKSATS-------------------------DKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS T+                          K  +PVKK + VVS SL         
Sbjct: 301  RGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K + Y+KSSKVPPGSGEGQKWTTL+HNG+IFPPPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 420

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFAVMLDTDYMNKP+FKENF +DW+K+LGK H IQNLEDCDF PIYEWHQ        
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 
Sbjct: 481  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+DNTVTWLA+WNDPIN KE KYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLK 600

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTLKVENVEP+PPN LKFDFLGKDSIRYQNEV+VEPAVFKAI QFRS     
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSGKEGS 720

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS++T GG+ AEKVVVYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHA 780

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKP  K  DGKP
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKP 840

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPEAL+RKIAQTNAKIEKMER+KE+KEDLKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 900

Query: 495  PIEKIFNKSLLAKFTWSMD 439
            PIEKIFNKSLLAKF W+M+
Sbjct: 901  PIEKIFNKSLLAKFAWAMN 919


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score = 1083 bits (2801), Expect = 0.0
 Identities = 582/926 (62%), Positives = 662/926 (71%), Gaps = 33/926 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC  P +++DM++D+ P++FKRS  + KQNQ NS+ K+ LS +K+  +     SD+   
Sbjct: 4    EACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSE-KKKLSLQKHVGQSAVHTSDVRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  + P V                  +  P  NSK S  AT  +K  
Sbjct: 63   NGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQ 122

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + PAA+ + N+E S+D+KPL AR     SK KSN+ANK  G    
Sbjct: 123  NHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSCS 181

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P I + EDS+DEKPLS +F            S D DE KKP+  K+ +NG       
Sbjct: 182  IRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDE-KKPLATKVQQNGSASRDGP 240

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++L KR   E+KS   SS+KK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 241  MNKSASLLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2217 ITKKSATS-------------------------DKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS T+                          K  +PVKK + VVS SL         
Sbjct: 301  RGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K + Y+KSSKVPPGSGEGQKWTTL+HNG++F PPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKXQPLTLTPEQEEV 420

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFAVMLDTDYM KP+FKENF +DW+K+LGK H +QNLEDCDF PIYEWHQ        
Sbjct: 421  ATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQ 480

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 
Sbjct: 481  MTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+DNTVTWLAFWNDPIN KE KYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDPINQKECKYVFLAASSTLK 600

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTLKVENVEP+PPN LK DF+GKDSIRYQNEV+VEPAVFKAIQQFRS     
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGC 720

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ETKGG  AEKV VYQHA
Sbjct: 721  ADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHA 780

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKPP K  DG+P
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPAKGADGEP 840

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPE+L+RKIAQTNAKIEKMER+K++KEDLK VAL TSKI+YLDPRITVAWCKRHEV
Sbjct: 841  KRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRHEV 900

Query: 495  PIEKIFNKSLLAKFTWSMDVDPSFRF 418
            PIEKIFNKSLLAKF WSMDVDPSFRF
Sbjct: 901  PIEKIFNKSLLAKFAWSMDVDPSFRF 926


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score = 1082 bits (2799), Expect = 0.0
 Identities = 583/919 (63%), Positives = 660/919 (71%), Gaps = 33/919 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC    +++DM++D+ P++FKRS  + KQNQ NS+ K+ LS +++  +     SD+   
Sbjct: 4    EACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSE-KKKLSLQRHVGQSAVHTSDVRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  K P V                  +     NSKPS  AT  +K  
Sbjct: 63   NGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAGANSKPSASATSTAKQQ 122

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + PAA+ + N+E S+D+KPLSAR     SK KSN+ANK  G    
Sbjct: 123  NHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGGDSCS 181

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P I + EDS+DEKPLS +F            S D DE KKP+ AK+  NG       
Sbjct: 182  IRRPVIEESEDSEDEKPLSRRFTSKSSLGESTSKSYDSDE-KKPLAAKVQPNGSASRDSP 240

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++  KRP  E+KS   SS+KK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 241  MNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2217 ITKKSATS-------------------------DKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS T+                          K  +PVKK + VVS SL         
Sbjct: 301  RGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K + Y+KSSKVPPGSGEGQKWTTL+HNG+IFPPPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 420

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFAVMLDTDYMNKP+FKENF +DW+K+LGK H IQNLEDCDF PIYEWHQ        
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI 
Sbjct: 481  MTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIR 540

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+DNTVTWLA+WNDPIN KE KYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAASSTLK 600

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTLKVENVEP+PPN LKFDFLGKDSIRYQNEV+VEPAVFKAIQQFRS     
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS++T GG+ AEKVVVYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVVYQHA 780

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKP  K  DGKP
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGADGKP 840

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPEAL+RKIAQTNAKIEKMER+KE+KEDLKTVALGTSKINYLDPRITVAWCKRHEV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEV 900

Query: 495  PIEKIFNKSLLAKFTWSMD 439
            PIEKIFNKSLLAKF W+M+
Sbjct: 901  PIEKIFNKSLLAKFAWAMN 919


>gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythranthe guttata]
          Length = 883

 Score = 1079 bits (2791), Expect = 0.0
 Identities = 584/899 (64%), Positives = 655/899 (72%), Gaps = 6/899 (0%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDE-PLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYS 2920
            EA     M++DMD+DD+ PLVFKRS SS K  Q  S+ +  LSS+K++ + G   SD+  
Sbjct: 4    EAREDKNMMEDMDDDDDAPLVFKRSGSSSKPKQ--SEPENKLSSQKHNAQVGRQSSDVRP 61

Query: 2919 ENEKISGVQKVKMAPPLKA--PSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKS 2746
            +N   +  QK K      +  P V                  +  P+ NSKPST    +S
Sbjct: 62   QNGTNANAQKGKSVTSSSSMKPPVRPSLVSPKSSNSSVKASPIKSPDVNSKPSTSVVGES 121

Query: 2745 KIINKQIEEEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANKGTL-QLDTK 2569
            K +   I+EE            N+EDSEDDKPLSAR   G SK   N  NK     L  K
Sbjct: 122  KSVKSTIKEE------------NSEDSEDDKPLSARQVAGSSKNNPNQTNKPNAPNLGKK 169

Query: 2568 PSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVA-KIHKNGXXXXXXXXX 2392
             ++PK EDSDDE PLS+KFQ           S    EEKKP+VA K  KNG         
Sbjct: 170  SNVPKPEDSDDEIPLSAKFQGKSNAGASTSRS-SHSEEKKPLVARKPDKNGSASTERKPS 228

Query: 2391 XXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQIT 2212
               T+L+KRPA  + S G S++KK KLS  S+    K+ S K E KA      +P+SQ T
Sbjct: 229  ---TVLQKRPADGVASAGQSNLKKPKLSD-SLASKDKKASVKPEVKAEDDEDLVPLSQRT 284

Query: 2211 KKSATSDKKLSPVKKIT-KVVSTSLXXXXXXXXXXXKTSNYSKSSKVPPGSGEGQKWTTL 2035
            KKS T +KK SP  K   K  S +            K +NYSKSSK+PP SG+GQKWTTL
Sbjct: 285  KKSTTPEKKPSPALKTNNKTNSKTNSKTNKKSKQVSKDNNYSKSSKLPPSSGDGQKWTTL 344

Query: 2034 IHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEAATMFAVMLDTDYMNKPKFKENFMNDW 1855
            +HNG+IFPPPYKPHGVKMLYKGKPV+LTPEQEE ATM+AVML+TDY+ KP+FKENFM DW
Sbjct: 345  VHNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVMLETDYLKKPQFKENFMTDW 404

Query: 1854 RKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVN 1675
            +K+LGK H+IQ+LE CDFTPIYEWHQ                          KYMWA+++
Sbjct: 405  KKILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKALKEEKLKLEEKYMWAVLD 464

Query: 1674 GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGNDAQIPECPIPGESWKE 1495
            GV+EKVGNFRVEPPGLFRGRGEHPKMGKLK+RI PSDITINIG DA IPECPI GE WKE
Sbjct: 465  GVREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGRDAPIPECPIEGERWKE 524

Query: 1494 IRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLKGQSDKEKYEKARLLKDYIQGIRAAYT 1315
            IRHDNTVTWLA+W+DPIN KE KYVFLAASSTLKGQSDKEKYEKARLLKDYIQGIR AYT
Sbjct: 525  IRHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIQGIRTAYT 584

Query: 1314 KGFTSKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPLPPNSLKFD 1135
            + F SKD  KKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+PPN LKFD
Sbjct: 585  RDFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFD 644

Query: 1134 FLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXXXXXXXXXDTSKLNAHLKELMPGLTAKV 955
            FLGKDSIRYQNEVEVE AVFKAIQQFRS            DTSKLNAHLKELMPGLTAKV
Sbjct: 645  FLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTAKV 704

Query: 954  FRTYNASITLDDMLSRETKGGDAAEKVVVYQHANKEVAIICNHQRTVSKSHSAQILRLNE 775
            FRTYNASITLDD LSRETKGGD AEKVV Y HANKEVAIICNHQRTVSK+HSAQ+LRL+E
Sbjct: 705  FRTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICNHQRTVSKTHSAQMLRLDE 764

Query: 774  KIEELKGVLEELETDLVRAKKGKPPLKNTDGKPKRNMNPEALKRKIAQTNAKIEKMEREK 595
            KI+ELKGVLEEL+TDL RA+KGKP L   DGK KRN+NPEAL+RKIAQT AKIEKMER+K
Sbjct: 765  KIDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEALERKIAQTTAKIEKMERDK 824

Query: 594  ESKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWSMDVDPSFRF 418
            E+KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLL KF+W+MDVDPSFRF
Sbjct: 825  ETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLEKFSWAMDVDPSFRF 883


>ref|XP_012845487.1| PREDICTED: DNA topoisomerase 1-like [Erythranthe guttatus]
          Length = 894

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 585/910 (64%), Positives = 657/910 (72%), Gaps = 17/910 (1%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDE-PLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYS 2920
            EA     M++DMD+DD+ PLVFKRS SS K  Q  S+ +  LSS+K++ + G   SD+  
Sbjct: 4    EAREDKNMMEDMDDDDDAPLVFKRSGSSSKPKQ--SEPENKLSSQKHNAQVGRQSSDVRP 61

Query: 2919 ENEKISGVQKVKMAPPLKA--PSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKS 2746
            +N   +  QK K      +  P V                  +  P+ NSKPST    +S
Sbjct: 62   QNGTNANAQKGKSVTSSSSMKPPVRPSLVSPKSSNSSVKASPIKSPDVNSKPSTSVVGES 121

Query: 2745 KIINKQIEEEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANKGTL-QLDTK 2569
            K +   I+EE            N+EDSEDDKPLSAR   G SK   N  NK     L  K
Sbjct: 122  KSVKSTIKEE------------NSEDSEDDKPLSARQVAGSSKNNPNQTNKPNAPNLGKK 169

Query: 2568 PSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVA-KIHKNGXXXXXXXXX 2392
             ++PK EDSDDE PLS+KFQ           S    EEKKP+VA K  KNG         
Sbjct: 170  SNVPKPEDSDDEIPLSAKFQGKSNAGASTSRS-SHSEEKKPLVARKPDKNGSASTERKPS 228

Query: 2391 XXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQIT 2212
               T+L+KRPA  + S G S++KK KLS  S+    K+ S K E KA      +P+SQ T
Sbjct: 229  ---TVLQKRPADGVASAGQSNLKKPKLSD-SLASKDKKASVKPEVKAEDDEDLVPLSQRT 284

Query: 2211 KKSATSDKKLSPVKKITKVV------------STSLXXXXXXXXXXXKTSNYSKSSKVPP 2068
            KKS T +KK SP  K+TK              S +            K +NYSKSSK+PP
Sbjct: 285  KKSTTPEKKPSPALKVTKSTASISKKTNNKTNSKTNSKTNKKSKQVSKDNNYSKSSKLPP 344

Query: 2067 GSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEAATMFAVMLDTDYMNK 1888
             SG+GQKWTTL+HNG+IFPPPYKPHGVKMLYKGKPV+LTPEQEE ATM+AVML+TDY+ K
Sbjct: 345  SSGDGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVMLETDYLKK 404

Query: 1887 PKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXXXXX 1708
            P+FKENFM DW+K+LGK H+IQ+LE CDFTPIYEWHQ                       
Sbjct: 405  PQFKENFMTDWKKILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKALKEEKLK 464

Query: 1707 XXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGNDAQIP 1528
               KYMWA+++GV+EKVGNFRVEPPGLFRGRGEHPKMGKLK+RI PSDITINIG DA IP
Sbjct: 465  LEEKYMWAVLDGVREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGRDAPIP 524

Query: 1527 ECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLKGQSDKEKYEKARLLK 1348
            ECPI GE WKEIRHDNTVTWLA+W+DPIN KE KYVFLAASSTLKGQSDKEKYEKARLLK
Sbjct: 525  ECPIEGERWKEIRHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKYEKARLLK 584

Query: 1347 DYIQGIRAAYTKGFTSKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 1168
            DYIQGIR AYT+ F SKD  KKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV
Sbjct: 585  DYIQGIRTAYTRDFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV 644

Query: 1167 EPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXXXXXXXXXDTSKLNAHL 988
            EP+PPN LKFDFLGKDSIRYQNEVEVE AVFKAIQQFRS            DTSKLNAHL
Sbjct: 645  EPVPPNILKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDTSKLNAHL 704

Query: 987  KELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHANKEVAIICNHQRTVSK 808
            KELMPGLTAKVFRTYNASITLDD LSRETKGGD AEKVV Y HANKEVAIICNHQRTVSK
Sbjct: 705  KELMPGLTAKVFRTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICNHQRTVSK 764

Query: 807  SHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKPKRNMNPEALKRKIAQT 628
            +HSAQ+LRL+EKI+ELKGVLEEL+TDL RA+KGKP L   DGK KRN+NPEAL+RKIAQT
Sbjct: 765  THSAQMLRLDEKIDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEALERKIAQT 824

Query: 627  NAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTW 448
             AKIEKMER+KE+KEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLL KF+W
Sbjct: 825  TAKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLEKFSW 884

Query: 447  SMDVDPSFRF 418
            +MDVDPSFRF
Sbjct: 885  AMDVDPSFRF 894


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score = 1075 bits (2780), Expect = 0.0
 Identities = 577/926 (62%), Positives = 661/926 (71%), Gaps = 33/926 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC  P +++DM++D+ P++FKRS  + KQNQ NS+ K+ LS +K+  +     SD+   
Sbjct: 4    EACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSE-KKKLSLQKHVGQSAVHTSDVRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  + P V                  +  P  NSK S  AT  +K  
Sbjct: 63   NGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQ 122

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + PAA+ + N+E S+D+KPL AR     SK KSN+ANK  G    
Sbjct: 123  NHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSCS 181

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P I + EDS+DEKPLS +F            S D DE KKP+ AK+ +NG       
Sbjct: 182  IRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSHDSDE-KKPLAAKVQQNGSASRDGP 240

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++  KR   E+KS   SS+KK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 241  MNKSASLSNKRAPGEVKSLNQSSLKKPKLSSTITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2217 ITKKSATS-------------------------DKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS T+                          K  +PVKK + VVS SL         
Sbjct: 301  RGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K + Y+KSSKVPPGSGEGQKWTTL+HNG++FPPPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEV 420

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFA MLDTDYMNKP+FKENF +DW+K+LGK H IQNLEDCDF PIYEWHQ        
Sbjct: 421  ATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI 
Sbjct: 481  MTTEEKKALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIR 540

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+DNTVTWLA+WNDP+N KE KYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAASSTLK 600

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQ+AVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGNEKDD 660

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTLKVENVEP+PPN LK DF+GKDSIRYQNEV+VEPAVFKAIQQFRS     
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ETKGG  AEKV VYQ A
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQRA 780

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKPP K  DG+P
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEP 840

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPEAL+RKIAQTNAKIEKMER+K++KEDLK VAL TSKI+YLDPRITVAWCKR EV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEV 900

Query: 495  PIEKIFNKSLLAKFTWSMDVDPSFRF 418
            PIEK+FNKSLLAKF W+MDVDPSFRF
Sbjct: 901  PIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score = 1074 bits (2778), Expect = 0.0
 Identities = 575/926 (62%), Positives = 663/926 (71%), Gaps = 33/926 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC    +++DM++D+ P++FKRS  + KQNQ N++ K+ LS +K+  +     SD+   
Sbjct: 4    EACTTTNLMEDMEDDEGPVIFKRSNPTSKQNQANAE-KKKLSLQKHVGQSAVHTSDVRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  + P V                  +  P  NSK S  AT  +K  
Sbjct: 63   NGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQ 122

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + PAA+ + N+E S+D+KPL AR     S  KSN+ANK  G    
Sbjct: 123  NHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLIARTSGCSSMGKSNHANKEGGDSCS 181

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P I + EDS+DEKPLS +F            S D DE KKP+ AK+ +NG       
Sbjct: 182  IRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDE-KKPLAAKVQQNGSASPEGP 240

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++  KR   E+KS   SS+KK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 241  MNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2217 ITKKSATS-------------------------DKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS T+                          K  +PVKK + VVSTSL         
Sbjct: 301  RGKKSQTAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKKASTVVSTSLKKVNKKSKK 360

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              + + Y+KSSKVPPGSGEGQKWTTL+HNG++FPPPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 361  VIRKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEV 420

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFAVMLDTDYMNKP+FKENF +DW+K+LGK H IQNLEDCDF PIYEWHQ        
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI 
Sbjct: 481  MTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIR 540

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+DNTVTWLA+WNDP+N KE KYVFLAASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNIKECKYVFLAASSTLK 600

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQS KEKYEKAR+LKDYI GIRAAYTKGFT+ KD  KKQIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSVKEKYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTLKVENVEP+PPN LK DF+GKDSIRYQNEV+VEPAVFKAIQQFRS     
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ETKGG  AEKV VYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKIAEKVAVYQHA 780

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKPP K+ DG+P
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKDADGEP 840

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPE+L+RKIAQTNAKIEKMER+K++KEDLK VAL TSKI+YLDPRITVAWCKR EV
Sbjct: 841  KRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEV 900

Query: 495  PIEKIFNKSLLAKFTWSMDVDPSFRF 418
            PIEK+FNKSLLAKF W+MDVDPSFRF
Sbjct: 901  PIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score = 1071 bits (2770), Expect = 0.0
 Identities = 575/926 (62%), Positives = 659/926 (71%), Gaps = 33/926 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC    +++DM++D+ P++FKRS  + KQNQ NS+ K+ LS +K+  +     SD+   
Sbjct: 4    EACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSE-KKKLSLQKHVGQSAVHTSDVRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  + P V                  +  P  NSK S  AT  +K  
Sbjct: 63   NGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQ 122

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + P A+ + N+E S+D+KPL AR     SK KSN+ANK  G    
Sbjct: 123  NHHKSSAAFIEPKP-SVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSCS 181

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P + + EDS+DEKPLS +F            S D DE KKP+ AK+ +NG       
Sbjct: 182  IRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDE-KKPLAAKVQQNGSASRDGP 240

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++  KR   E+KS   SS+KK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 241  MNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2217 ITKKSATS-------------------------DKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS T+                          K  +PVKK + VVS SL         
Sbjct: 301  RGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K + Y+KSSKVPPGSGEGQKWTTL+HNG++FPPPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPEQEEV 420

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFA MLDTDYMNKP+FKENF +DW+K+LGK H IQNLEDCDF PIYEWHQ        
Sbjct: 421  ATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEREKKKQ 480

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI 
Sbjct: 481  MTTEEKKALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIH 540

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+DNTVTWLA+WNDP+N KE KYVFLA SSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLK 600

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTLKVENVEP+PPN LK DF+GKDSIRYQNEV+VEPAVFKAIQQFRS     
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ETKGG  AEKV VYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHA 780

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKPP K  DG+P
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEP 840

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPEAL+RKIAQTNAKIEKMER+K++KEDLK VAL TSKI+YLDPRITVAWCKR EV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEV 900

Query: 495  PIEKIFNKSLLAKFTWSMDVDPSFRF 418
            PIEK+FNKSLLAKF W+MDVDPSFRF
Sbjct: 901  PIEKMFNKSLLAKFAWAMDVDPSFRF 926


>dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]
          Length = 920

 Score = 1059 bits (2739), Expect = 0.0
 Identities = 571/919 (62%), Positives = 652/919 (70%), Gaps = 33/919 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC  P +++DM++D+ P++FKRS  + KQNQ NS+ K+ LS +K+  +     SD+   
Sbjct: 4    EACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSE-KKKLSLQKHVGQSAVHTSDVRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  + P V                  +  P  NSK S  AT  +K  
Sbjct: 63   NGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQ 122

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + PAA+ + N+E S+D+KPL AR     SK KSN+ANK  G    
Sbjct: 123  NHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSCS 181

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P I + EDS+DEKPLS +F            S D DE KKP+ AK+  NG       
Sbjct: 182  IRRPVIEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDE-KKPLAAKVQPNGSASRDGP 240

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++  KR   E+KS   SS+KK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 241  MNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2217 ITKKSATS-------------------------DKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS T+                          K  +PVKK + VVS SL         
Sbjct: 301  RGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K + Y+KSSKVPPGSGEGQKWTTL+HNG+IFPPPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPEQEEV 420

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFAVMLDTDYMNKP+FKENF +DW+K+LGK H IQNLEDCDF PIYEWHQ        
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKEKKKQ 480

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMW IV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI 
Sbjct: 481  MTTEEKKALKEERLQQEEKYMWVIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIR 540

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+DNTVTWLA+WNDPIN KE KYVFL ASSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKERKYVFLGASSTLK 600

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTLKVENVEP+PPN LK DF+GKDSIRYQNEV+VEPAVFKAIQQFRS     
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ETKGG  AEKV VYQHA
Sbjct: 721  ADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHA 780

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKPP K  DG+P
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGADGEP 840

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPEAL+RKIAQTNAKIEKME +K++KEDLK VAL TSKI+YL PRITVAWCKRHEV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMEGDKKTKEDLKAVALSTSKISYLGPRITVAWCKRHEV 900

Query: 495  PIEKIFNKSLLAKFTWSMD 439
            PIEK+FNKSLLAKF W+M+
Sbjct: 901  PIEKMFNKSLLAKFAWAMN 919


>ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo nucifera]
          Length = 890

 Score = 1058 bits (2735), Expect = 0.0
 Identities = 570/908 (62%), Positives = 648/908 (71%), Gaps = 15/908 (1%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            +AC KPK  DD D+D+ P++FKR+ +S K+NQ N + K+ +SS+K D   G  VSD +S 
Sbjct: 5    DACIKPKFFDDGDDDEGPIIFKRNNASSKKNQLNKELKK-VSSRKRDGSSGKCVSDSFSP 63

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S +QK K     KA +                        T+SK ST  TDK K  
Sbjct: 64   NGQNSSLQKGKAVQSSKASTGKST-------------------ETSSKASTSITDKLKCS 104

Query: 2736 ---NKQIEE-EKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFS--KAKSNNANKG----- 2590
               N  I+  EK L +P  EP  ++ DS+DDKPLS R P   S  K KS+  +KG     
Sbjct: 105  PQKNSSIDNMEKQLKKPCNEPYTDSVDSDDDKPLSIRLPTSASLLKCKSSPVSKGLSSPV 164

Query: 2589 -TLQLDTKPSIPKY---EDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKN 2422
             +     K ++      EDS+DE PLS K +             D  EEK P+V+K+ +N
Sbjct: 165  ASSSQSEKTNVTNKKSSEDSEDELPLSLKLKLKPSVGLSGKKFYDSGEEK-PLVSKLQQN 223

Query: 2421 GXXXXXXXXXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXX 2242
            G              L KRP +   S+G S VKK K+S  SVP   KQ S K+EPK    
Sbjct: 224  GSSKRDNEPLKSPKNLNKRPLSGANSSGQSLVKKLKVSEVSVPTKVKQTSIKSEPKEEDE 283

Query: 2241 XXDLPISQITKKSATSDKKLSPVKKITKVVSTSLXXXXXXXXXXXKTSNYSKSSKVPPGS 2062
               +PISQ  KKSA+SD K   +KK TKVVS+S            K S YSKS+K+PP S
Sbjct: 284  DD-IPISQRLKKSASSDDKSLSLKKTTKVVSSSFKKTTNKLKKAAKNSKYSKSTKMPPSS 342

Query: 2061 GEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEAATMFAVMLDTDYMNKPK 1882
            GEGQKWTTL HNG+IFPP YKPHGVKMLY GKPVDLTPEQEE ATMFAVM DTDY  K +
Sbjct: 343  GEGQKWTTLEHNGVIFPPLYKPHGVKMLYNGKPVDLTPEQEEVATMFAVMKDTDYATKSR 402

Query: 1881 FKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXX 1702
            F ENFMNDWR +LGK H+I+  E CDFTPIYEWHQ                         
Sbjct: 403  FIENFMNDWRTILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSAEEKKALKEEKLKQE 462

Query: 1701 XKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGNDAQIPEC 1522
             KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDITINIG  A IPEC
Sbjct: 463  EKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKGAPIPEC 522

Query: 1521 PIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLKGQSDKEKYEKARLLKDY 1342
            PIPGE WKE+RHDNTVTWLAFWNDPINPKE KYVFLAASS+LKGQSDKEKYEKARLLKDY
Sbjct: 523  PIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDY 582

Query: 1341 IQGIRAAYTKGFTSKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP 1162
            I+ IRA YT+ F SKD+TK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 
Sbjct: 583  IKDIRANYTRDFVSKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEL 642

Query: 1161 LPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXXXXXXXXXDTSKLNAHLKE 982
            +PPN L+FDFLGKDSIRY N VEVE AV+KAI QF++            DTSKLNAHLKE
Sbjct: 643  VPPNKLQFDFLGKDSIRYFNTVEVELAVYKAIGQFKNGKEDGEDLFDSLDTSKLNAHLKE 702

Query: 981  LMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHANKEVAIICNHQRTVSKSH 802
            LMPGLTAKVFRTYNASITLD+ML+RE+KGGD AEK+ VYQHANKEVAIICNHQR+VSKSH
Sbjct: 703  LMPGLTAKVFRTYNASITLDEMLNRESKGGDVAEKIAVYQHANKEVAIICNHQRSVSKSH 762

Query: 801  SAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKPKRNMNPEALKRKIAQTNA 622
            SAQ+ RL++KI+ELK  L+EL+TDL RAKKGKPPLK  DGKPKRN+ PEAL++KIAQ NA
Sbjct: 763  SAQMHRLDDKIKELKDALDELKTDLARAKKGKPPLKGADGKPKRNLTPEALEKKIAQANA 822

Query: 621  KIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWSM 442
            KIEKMER+K+ KEDLKTVALGTSKINYLDPRI+VAWCKRHEVPIEKIFNKSLLAKF W+M
Sbjct: 823  KIEKMERDKQIKEDLKTVALGTSKINYLDPRISVAWCKRHEVPIEKIFNKSLLAKFAWAM 882

Query: 441  DVDPSFRF 418
            DVDP FRF
Sbjct: 883  DVDPDFRF 890


>dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score = 1055 bits (2729), Expect = 0.0
 Identities = 568/919 (61%), Positives = 653/919 (71%), Gaps = 33/919 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC    +++DM++D+ P++FKRS  + KQNQ NS+ K+ LS +K+  +     SD+   
Sbjct: 4    EACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSE-KKKLSLQKHVGQSAVHTSDVRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  + P V                  +  P  NSK S  AT  +K  
Sbjct: 63   NGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQ 122

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + P A+ + N+E S+D+KPL AR     SK KSN+ANK  G    
Sbjct: 123  NHHKSSAAFIEPKP-SVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSCS 181

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P + + EDS+DEKPLS +F            S D DE KKP+ AK+ +NG       
Sbjct: 182  IRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDE-KKPLAAKVQQNGSASRDGP 240

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++  KR   E+KS   SS+KK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 241  MNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2217 ITKKSATS-------------------------DKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS T+                          K  +PVKK + VVS SL         
Sbjct: 301  RGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K + Y+KSSKVPPGSGEGQKWTTL+HNG+IFPPPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPLTLTPEQEEV 420

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFAVMLDTDYMNKP+FKENF +DW+K+LGK H IQNLEDCDF PIYEWHQ        
Sbjct: 421  ATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEREKKKQ 480

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI 
Sbjct: 481  MTTEEKKALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIH 540

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+DNTVTWLA+WNDP+N KE KYVFLA SSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLK 600

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTL+VENVEP+PPN LK DF+GKDSIRYQNEV+VEPAVFKAIQQFRS     
Sbjct: 661  DEADTVGCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ETKGG  AEKV VYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHA 780

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKPP K  DG+P
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEP 840

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPEAL+RKIAQTNAKIEKMER+K++KEDLK VAL TSKI+YLDPRITVAWCKR EV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEV 900

Query: 495  PIEKIFNKSLLAKFTWSMD 439
            PIEK+FNKSLLAKF W+M+
Sbjct: 901  PIEKMFNKSLLAKFAWAMN 919


>dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]
          Length = 920

 Score = 1043 bits (2698), Expect = 0.0
 Identities = 564/919 (61%), Positives = 650/919 (70%), Gaps = 33/919 (3%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDEPLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIYSE 2917
            EAC    +++DM++D+ P++FKRS  + KQNQ NS+ K+ LS +K+  +     SD+   
Sbjct: 4    EACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSE-KKKLSLQKHVGQSAVHTSDVRPA 62

Query: 2916 NEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSKII 2737
            N + S  QK ++ P  + P V                  +  P  NSK S  AT  +K  
Sbjct: 63   NGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATSTAKQQ 122

Query: 2736 NKQIE-----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQL 2578
            N         E KP + P A+ + N+E S+D+KPL AR     SK KSN+ANK  G    
Sbjct: 123  NHHKSSAAFIEPKP-SVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGGDSCS 181

Query: 2577 DTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXXX 2398
              +P + + EDS+DEKPLS +F            S D DE KKP+ AK+ +NG       
Sbjct: 182  IRRPVVEESEDSEDEKPLSRRFPSKSSLGESTSKSYDSDE-KKPLAAKVQQNGSASRDGP 240

Query: 2397 XXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPISQ 2218
                +++  KR   E+KS   SS+KK KLSS    I++KQ + K EPKA     ++P+SQ
Sbjct: 241  MNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNIPLSQ 300

Query: 2217 ITKKSATS-------------------------DKKLSPVKKITKVVSTSLXXXXXXXXX 2113
              KKS T+                          K  +PVKK + VVS SL         
Sbjct: 301  RGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNKKSKK 360

Query: 2112 XXKTSNYSKSSKVPPGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEA 1933
              K + Y+KSSKVPPGSGEGQKWTTL+HNG++F PPYKPHGVKMLYK +P+ LTPEQEE 
Sbjct: 361  VIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKQQPLTLTPEQEEV 420

Query: 1932 ATMFAVMLDTDYMNKPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXX 1753
            ATMFAVMLDTDYM KP+FKENF +DW+K+LGK H +QNLEDCDF PIYEWHQ        
Sbjct: 421  ATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKEKRKQ 480

Query: 1752 XXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIC 1573
                              KYM AIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLKKRI 
Sbjct: 481  MTTEEKKALKEERLQQEEKYMRAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLKKRIH 540

Query: 1572 PSDITINIGNDAQIPECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLK 1393
            P DITINIG DA IPECPIPGE WKE+R+DNTVTWLA+WNDP+N KE KYVFLA SSTLK
Sbjct: 541  PRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPSSTLK 600

Query: 1392 GQSDKEKYEKARLLKDYIQGIRAAYTKGFTS-KDLTKKQIAVATYLIDKLALRAGNEKDD 1216
            GQSDKEKYEKARLLKDYI GIRAAYTK FT+ KD  KKQIAVATYLIDKLALRAGNEKDD
Sbjct: 601  GQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGNEKDD 660

Query: 1215 DEADTVGCCTLKVENVEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXX 1036
            DEADTVGCCTLKVENVEP+PPN LK DF+GKDSIRYQNEV+VEPAVFKAIQQFRS     
Sbjct: 661  DEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSGKEGS 720

Query: 1035 XXXXXXXDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHA 856
                   DTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLS+ETKGG  AEKV VYQHA
Sbjct: 721  EDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGVYQHA 780

Query: 855  NKEVAIICNHQRTVSKSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKP 676
            NKEVAIICNHQRTVSKSHSAQ+ RLNEKI+ELK  LEEL+TDL RAKKGKPP K  DG+P
Sbjct: 781  NKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGDDGEP 840

Query: 675  KRNMNPEALKRKIAQTNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEV 496
            KRN+NPEAL+RKIAQTNAKIEKMER+K++KEDLK VAL TSKI+YLDPRITVAWCKR EV
Sbjct: 841  KRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISYLDPRITVAWCKRQEV 900

Query: 495  PIEKIFNKSLLAKFTWSMD 439
            PIEK+FNKSLLAKF W+M+
Sbjct: 901  PIEKMFNKSLLAKFAWAMN 919


>ref|XP_009619726.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Nicotiana
            tomentosiformis]
          Length = 877

 Score = 1041 bits (2692), Expect = 0.0
 Identities = 564/901 (62%), Positives = 640/901 (71%), Gaps = 8/901 (0%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDE--PLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIY 2923
            EA +K K++ ++D+DD+  PLVFKRS ++ KQNQ NS      SS+K D + G   SD+ 
Sbjct: 4    EAFSKTKLMAEVDDDDDDMPLVFKRSSTTSKQNQSNS------SSQKQDGRSGRQASDVR 57

Query: 2922 SENEKISGVQKVKMAPPLKAPSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKSK 2743
            S N + S  QKVK     KA                        P  NS+PS  A +++K
Sbjct: 58   SPNGQSSSAQKVKAGTSSKASRAVSPFTSPKASPSSGRTS----PAPNSRPSASAGNQAK 113

Query: 2742 IINKQIE----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTLQ 2581
             +N+Q +    E K   EP +EP+D  EDSEDDKPLSAR   G SK+ S++ANK  GT  
Sbjct: 114  DVNQQSKIVPNEPKQAVEPKSEPNDEAEDSEDDKPLSARLSSGLSKSNSSHANKVLGTSA 173

Query: 2580 LDTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXXX 2401
               K   PK EDSDDE PL+S+FQ           S +  EE KP   KI +NG      
Sbjct: 174  SVQKSRPPKKEDSDDEIPLASRFQLKSNAGASTSKSSN-SEEVKP---KIRQNGLPST-- 227

Query: 2400 XXXXXSTMLKKRPATELKSTGHSSVKKTKLSSASVPINSKQPSGKAEPKAXXXXXDLPIS 2221
                  T+L KRP  ++       +K                S K E K      D+PIS
Sbjct: 228  ------TVLSKRPPGDVSLLLRLQLKSLGFLMHLHLFRVSXASVKPEKKTEDDDDDVPIS 281

Query: 2220 QITKKSATSDKKLSPVKKITKVVSTSLXXXXXXXXXXXKTSNYSKSSKVPPGSGEGQKWT 2041
            Q  KKS  S  KLS  KK TKVVS+S+             S YSKSSK+ P SGEGQKWT
Sbjct: 282  QRIKKSVASASKLSSAKKATKVVSSSMKTKKKLKK-----SKYSKSSKLQPSSGEGQKWT 336

Query: 2040 TLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEAATMFAVMLDTDYMNKPKFKENFMN 1861
            TL+HNG+IFPPPYKPHGVKMLYKGKPVDLTPEQEE ATM+AVMLDTDYM+K +FKENFMN
Sbjct: 337  TLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMSKLQFKENFMN 396

Query: 1860 DWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAI 1681
            DWRK+LGK H+IQNL+DCDFTPIYEWHQ                          KYMWAI
Sbjct: 397  DWRKILGKNHVIQNLDDCDFTPIYEWHQSEKEKKKQMSTEEKKALREEKLKQEEKYMWAI 456

Query: 1680 VNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGNDAQIPECPIPGESW 1501
            V+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI P+DITINIG  A IPECPIPGE W
Sbjct: 457  VDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGAPIPECPIPGERW 516

Query: 1500 KEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLKGQSDKEKYEKARLLKDYIQGIRAA 1321
            KE+RHDNTVTWLAFWNDPINP+E KYVFLAASS+LKGQSDKEKYEKAR LKDYI+GIR+A
Sbjct: 517  KEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIEGIRSA 576

Query: 1320 YTKGFTSKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPLPPNSLK 1141
            YTK FTSKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+PPN LK
Sbjct: 577  YTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILK 636

Query: 1140 FDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXXXXXXXXXDTSKLNAHLKELMPGLTA 961
            FDFLGKDSIRYQNEV V   VFKAIQ FRS            DTSKLNAHLKELMPGLTA
Sbjct: 637  FDFLGKDSIRYQNEVAVYEPVFKAIQLFRSGKKGGDDLFDKLDTSKLNAHLKELMPGLTA 696

Query: 960  KVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHANKEVAIICNHQRTVSKSHSAQILRL 781
            KVFRTYNAS+TL+  L++ T+GG+ AEKV VY  ANKEVAIICNHQR+VSKSHS QI +L
Sbjct: 697  KVFRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSVQISKL 756

Query: 780  NEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKPKRNMNPEALKRKIAQTNAKIEKMER 601
            NEKI+ELK +LEE + DL RAKKGKPPLK  DGK KRN+ PEAL++KI QTN KIE +ER
Sbjct: 757  NEKIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKIDQTNVKIENIER 816

Query: 600  EKESKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFTWSMDVDPSFR 421
            + E+KE+LKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLLAKF W+MDV+PSF 
Sbjct: 817  QIETKEELKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLAKFAWAMDVEPSFT 876

Query: 420  F 418
            F
Sbjct: 877  F 877


>ref|XP_009790344.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Nicotiana
            sylvestris]
          Length = 876

 Score = 1033 bits (2671), Expect = 0.0
 Identities = 569/911 (62%), Positives = 651/911 (71%), Gaps = 18/911 (1%)
 Frame = -3

Query: 3096 EACAKPKMIDDMDEDDE--PLVFKRSRSSLKQNQPNSKTKESLSSKKNDWKFGTPVSDIY 2923
            EA +K K++ ++D+DD+  PLVFKRS +S KQNQ NS      SS+K D + G  VSD+ 
Sbjct: 4    EAFSKTKLMAEVDDDDDDMPLVFKRSTTS-KQNQSNS------SSQKQDGRSGRQVSDVR 56

Query: 2922 SENEKISGVQKVKMAPPLKA-PSVXXXXXXXXXXXXXXXXXSMGLPNTNSKPSTLATDKS 2746
            S N + S  QKVK     KA P+V                     P  NS+PS  A +++
Sbjct: 57   SPNGQNSSAQKVKAGTSSKASPAVSPFTSPKASPSSSRIS-----PAPNSRPSASAGNQA 111

Query: 2745 KIINKQIE----EEKPLTEPAAEPSDNTEDSEDDKPLSARHPVGFSKAKSNNANK--GTL 2584
            K +N+Q +    E K   EP + P+D  EDSEDDKPLSAR   G SK+ S++ANK  GT 
Sbjct: 112  KNVNQQSKIVPNEPKQAVEPKSGPNDEAEDSEDDKPLSARLSSGLSKSISSHANKVLGTS 171

Query: 2583 QLDTKPSIPKYEDSDDEKPLSSKFQXXXXXXXXXXXSCDFDEEKKPIVAKIHKNGXXXXX 2404
                K   PK EDSDDE PL+S+FQ           S +  EE KP   KI +NG     
Sbjct: 172  ASVQKSKPPKKEDSDDEIPLASRFQLKSNAGASTSKSSN-SEEVKP---KIRQNGLPST- 226

Query: 2403 XXXXXXSTMLKKRPA--------TELKSTGH-SSVKKTKLSSASVPINSKQPSGKAEPKA 2251
                   T+L KRP          +LKS G    +   +LS ASV         K E K 
Sbjct: 227  -------TVLSKRPPGDVSLLLRLQLKSLGFLMHLHLFRLSXASV---------KPEKKT 270

Query: 2250 XXXXXDLPISQITKKSATSDKKLSPVKKITKVVSTSLXXXXXXXXXXXKTSNYSKSSKVP 2071
                 D+PISQ  KKS  S  K+S  KK TKVVS+S+             S YSKSSK+ 
Sbjct: 271  EDDDDDVPISQRIKKSVASASKVSSTKKATKVVSSSMKTKKKLKK-----SKYSKSSKLQ 325

Query: 2070 PGSGEGQKWTTLIHNGLIFPPPYKPHGVKMLYKGKPVDLTPEQEEAATMFAVMLDTDYMN 1891
            P SGEGQKWTTL+HNG+IFPP YKPHGVKMLYKGKP++LTPEQEE ATM+AVMLDT+YM+
Sbjct: 326  PSSGEGQKWTTLVHNGVIFPPSYKPHGVKMLYKGKPINLTPEQEEVATMYAVMLDTEYMS 385

Query: 1890 KPKFKENFMNDWRKVLGKKHIIQNLEDCDFTPIYEWHQXXXXXXXXXXXXXXXXXXXXXX 1711
            KP+FKENFMNDWRK+LGK H+IQNL+DCDFTPIYEWHQ                      
Sbjct: 386  KPQFKENFMNDWRKILGKNHVIQNLDDCDFTPIYEWHQSEKEKKKQMSTEEKKALREEKL 445

Query: 1710 XXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGNDAQI 1531
                KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI P+DITINIG  A I
Sbjct: 446  KQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGAPI 505

Query: 1530 PECPIPGESWKEIRHDNTVTWLAFWNDPINPKEIKYVFLAASSTLKGQSDKEKYEKARLL 1351
            PECPIPGE WKE+RHDNTVTWLAFWNDPINP+E KYVFLAASS+LKGQSDKEKYEKAR L
Sbjct: 506  PECPIPGERWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARRL 565

Query: 1350 KDYIQGIRAAYTKGFTSKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN 1171
            KDYI+GIR+AYTK FTSKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN
Sbjct: 566  KDYIEGIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVEN 625

Query: 1170 VEPLPPNSLKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSXXXXXXXXXXXXDTSKLNAH 991
            VEP+PPN LKFDFLGKDSIRYQNEV V   VFKAIQ FRS            DTSKLNAH
Sbjct: 626  VEPVPPNILKFDFLGKDSIRYQNEVAVYEPVFKAIQLFRSGKKGGDDLFDKLDTSKLNAH 685

Query: 990  LKELMPGLTAKVFRTYNASITLDDMLSRETKGGDAAEKVVVYQHANKEVAIICNHQRTVS 811
            LKELMPGLTAKVFRTYNAS+TL+  L++ T+GG+ AEKV VY  ANKEVAIICNHQR+VS
Sbjct: 686  LKELMPGLTAKVFRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVS 745

Query: 810  KSHSAQILRLNEKIEELKGVLEELETDLVRAKKGKPPLKNTDGKPKRNMNPEALKRKIAQ 631
            KSHS QI +LNEKI+ELK +LEE + DL RAKKGKPPLK  DGK KRN+ PEAL++K+ Q
Sbjct: 746  KSHSVQISKLNEKIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKMDQ 805

Query: 630  TNAKIEKMEREKESKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFT 451
            TNAKIE +E++ E+KE+LKTVALGTSKINYLDPRITVAWCKRHEVPIEK+FNKSLLAKF 
Sbjct: 806  TNAKIENIEKQIETKEELKTVALGTSKINYLDPRITVAWCKRHEVPIEKMFNKSLLAKFA 865

Query: 450  WSMDVDPSFRF 418
            W+MDV+PSF F
Sbjct: 866  WAMDVEPSFTF 876