BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Forsythia22_contig00000834
         (3497 letters)

Database: ./nr 
           69,698,275 sequences; 24,982,196,650 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_011093631.1| PREDICTED: DNA topoisomerase 1-like [Sesamum...  1130   0.0  
emb|CDP13767.1| unnamed protein product [Coffea canephora]           1073   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                1069   0.0  
dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]              1056   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]      1046   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...  1045   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]            1045   0.0  
gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythra...  1039   0.0  
dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]               1037   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]            1025   0.0  
dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]                1021   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                 1020   0.0  
dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]                 1018   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                 1017   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]              1013   0.0  
dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]             1008   0.0  
ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo...   995   0.0  
ref|XP_010252639.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo...   988   0.0  
ref|XP_009790344.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...   976   0.0  
ref|XP_009619726.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...   973   0.0  

>ref|XP_011093631.1| PREDICTED: DNA topoisomerase 1-like [Sesamum indicum]
          Length = 893

 Score = 1130 bits (2924), Expect = 0.0
 Identities = 598/859 (69%), Positives = 655/859 (76%), Gaps = 3/859 (0%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MA+E+C+  KL        EPLVFKR                      HDR L RP PDV
Sbjct: 1    MAIESCNDQKLMDDMDEDDEPLVFKRSSSSAKQSQGNSETKRPLSQK-HDRPLNRPSPDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA--TY 2216
              R QNG+S+++QK K                P++SNSSAKA  + P E + RPS   T 
Sbjct: 60   --RPQNGQSTMIQKSKTVPSSRTPPLRSPLASPKSSNSSAKALAVRPREVDPRPSTSVTD 117

Query: 2215 RSDNVNRPMKVGKPLIGSAAEPN-DSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXSRL 2039
             S++V   +K  KP   +    N DS+DSEDDKPLSARL  GL                 
Sbjct: 118  ESNSVKHQIKDEKPSTKATGGLNEDSEDSEDDKPLSARLPAGLSKVNSNHANKGPNALTS 177

Query: 2038 GQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSALRDSS 1859
             QK  IPK EDSDDE PLS+K Q+KSN G S    S  S E KPL+AK +QNGSA   S+
Sbjct: 178  VQKTKIPKPEDSDDEIPLSSKFQVKSNAGESTNRPSI-SGERKPLLAKYDQNGSA---SA 233

Query: 1858 SKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHVPISQ 1679
             +KPST+L KRPA  +KSAG+S +KK KLS+AS P   K+ S+K E K EDD+DHVPISQ
Sbjct: 234  ERKPSTILKKRPADGVKSAGESYLKKPKLSDASTPNKTKETSIKDEMKDEDDEDHVPISQ 293

Query: 1678 RMKKPATADKKSSAVKNITXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPGSGEGQKWTT 1499
            R+K+  ++DKKSS+ KN+T                            VPP SGEGQKWTT
Sbjct: 294  RIKQQTSSDKKSSSAKNMTKPISASAKKTSKKPKKVMKNSKYSKSSKVPPSSGEGQKWTT 353

Query: 1498 LIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEYMSKPKFKENFMSD 1319
            L+HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQEEVATM+AVMLDT+YM+KPKFKENFM+D
Sbjct: 354  LVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMNKPKFKENFMAD 413

Query: 1318 WRKILGKNHIIQNLEDCDFSPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIV 1139
            WRKILGKNH+IQ+LE CDF+PIYEWHQ                          KYMWAIV
Sbjct: 414  WRKILGKNHVIQSLEHCDFTPIYEWHQKEKEKKKQMTAEEKKALKEEKLKQEEKYMWAIV 473

Query: 1138 NGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPIPGERWK 959
            NGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIGK APIPECPIPGE WK
Sbjct: 474  NGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKDAPIPECPIPGESWK 533

Query: 958  EIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSRLLKDYIQGIRAAY 779
            EIRHDNTVTWLA+WNDPINPKEFKYVFLAASSTLKGQSDKEKYEK+RLLKDYI GIRAAY
Sbjct: 534  EIRHDNTVTWLAYWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAY 593

Query: 778  TKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPIPPNILKF 599
            TKDF +KD TKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+PPNILKF
Sbjct: 594  TKDFTNKDPTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKF 653

Query: 598  DFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLKELMPGLTAK 419
            DFLGKDSIRYQNEVEVE  VFKAIQQFRSGKK  DD+FD+LDTSKLNAHLKELMPGLTAK
Sbjct: 654  DFLGKDSIRYQNEVEVETPVFKAIQQFRSGKKGSDDMFDRLDTSKLNAHLKELMPGLTAK 713

Query: 418  VFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRTVSKSHSAQMLRLN 239
            VFRTYNASITLD+ LSRETKGGDVAE VVVYQHANKEVAIICNHQRTVSKSHSAQM RLN
Sbjct: 714  VFRTYNASITLDDKLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMTRLN 773

Query: 238  EKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKIAQTNAKIEKMERD 59
            EKIEELKGVLEEL TDL+RAKKGKPPLKSADGKPKRNLNP+ALEKKIAQTNAKIEKMERD
Sbjct: 774  EKIEELKGVLEELQTDLARAKKGKPPLKSADGKPKRNLNPDALEKKIAQTNAKIEKMERD 833

Query: 58   KETKEDLKTVALGTSKINY 2
            KETKEDLKTVALGTSKINY
Sbjct: 834  KETKEDLKTVALGTSKINY 852


>emb|CDP13767.1| unnamed protein product [Coffea canephora]
          Length = 926

 Score = 1073 bits (2775), Expect = 0.0
 Identities = 578/889 (65%), Positives = 640/889 (71%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEACS P L         PLVFKR                       D Q  R   DV
Sbjct: 1    MAVEACSTPSLLEDSDEENAPLVFKRTSSSSKQNLSNSETKKLSSQK-RDGQSSRNSSDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSATYRS 2210
                 NG+SS  Q G++               P+A+N SAK   +  P AN +PS++  +
Sbjct: 60   C--PVNGQSSSAQTGRVVSSAKTPPAKSPLSSPKAANISAKTSLITSPGANSKPSSSTSA 117

Query: 2209 ------DNVNRPM-KVGKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
                  ++ N P+ K+ K  + +A   +  +DS+DDKPL A+L +G              
Sbjct: 118  TVKQLENHKNSPVVKLPKRSVSAAKLSSTPEDSDDDKPLMAKLPSGSSRAIVNHGNKDGD 177

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S L QKP + + EDSDDEKPLS++   KSN+  S  SKS +  E K L AK+ QNGSAL
Sbjct: 178  GSSLVQKPGVEEDEDSDDEKPLSSRYLSKSNLVESI-SKSRNPGEKKSLPAKVQQNGSAL 236

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDD-- 1697
            RD    K S++ +KRP  E+KS+ +S VKK KLS  +  IN KQA++KAEPKVEDDDD  
Sbjct: 237  RDGPVGKSSSLSNKRPPGEVKSSDESAVKKPKLSGPTAAINKKQATLKAEPKVEDDDDDI 296

Query: 1696 ------------------------HVPISQRMKKPATADKKSSAVKNITXXXXXXXXXXX 1589
                                    HVPI+QRMKK  T+  +SS+VK +            
Sbjct: 297  LISQTAKKMFASASKPKSNDDDDDHVPITQRMKKSTTSVSQSSSVKKVAKVVSSSLKKTN 356

Query: 1588 XXXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTP 1409
                             VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYKG+PV LTP
Sbjct: 357  KKSKKIIKKSKYSKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKGQPVTLTP 416

Query: 1408 EQEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXX 1229
            EQEEVATMFAVMLDT+YMSKP+FKENF SDW++ILGKNH IQNLEDCDF PIYEWHQ   
Sbjct: 417  EQEEVATMFAVMLDTDYMSKPQFKENFFSDWKRILGKNHTIQNLEDCDFRPIYEWHQKEK 476

Query: 1228 XXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKL 1049
                                   KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKL
Sbjct: 477  EKKKQMTTEEKKSLKEEKLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKL 536

Query: 1048 KRRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAA 869
            K+RIRP DITINIGK APIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAA
Sbjct: 537  KKRIRPRDITINIGKDAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAA 596

Query: 868  SSTLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGN 689
            SSTLKGQSDKEKYEK+RLLKDYI GIR AYTKDFASKD  KKQIAVATYLIDKLALRAGN
Sbjct: 597  SSTLKGQSDKEKYEKARLLKDYIHGIRTAYTKDFASKDPMKKQIAVATYLIDKLALRAGN 656

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEVEVE  VFKAIQQFRSG
Sbjct: 657  EKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVESGVFKAIQQFRSG 716

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+  +D+FDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLSR+T GGDV E VVV
Sbjct: 717  KEGSEDLFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRKTNGGDVLEKVVV 776

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQ ANKEVAIICNHQRTVSK+HSAQM RLNEKIEELKGVLEEL TDLSRAKKGKPPLK+A
Sbjct: 777  YQQANKEVAIICNHQRTVSKTHSAQMSRLNEKIEELKGVLEELKTDLSRAKKGKPPLKNA 836

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DGKPKRNLNPEALE+KIAQTNAKIEKMERDKETKEDLKTVALGTSKINY
Sbjct: 837  DGKPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 885


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score = 1069 bits (2764), Expect = 0.0
 Identities = 580/883 (65%), Positives = 642/883 (72%), Gaps = 27/883 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC  P L        EP+VFKR                     K D Q  R + D 
Sbjct: 1    MAVEACPTPNLRDDMDEDDEPIVFKR-NNSASKQSQTNSETRKVSSQKRDGQSVRQIYD- 58

Query: 2389 HVRSQNGKSSVVQKGKM--------------AXXXXXXXXXXXXXXPEASNSSAKAYPLM 2252
              R  NG+SS  QKG+M              +              P+ S SSAK  P+ 
Sbjct: 59   -SRPANGESSSGQKGRMVPPSKPSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPVS 117

Query: 2251 PPEANLRPSAT----------YRSDNVNRPMKVGKPLIGSAAEPNDSDDSEDDKPLSARL 2102
               AN +PS +          ++S  V +  K   PL  ++A  NDS+DS+D KPLS R 
Sbjct: 118  SLPANSKPSTSGSFKVKPFNQHKSATVIKEEK-SSPLRLASAIINDSEDSDDGKPLSLRH 176

Query: 2101 STGLXXXXXXXXXXXXXXSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDS 1922
            S                 +++ ++ S P+ EDSDDEKPLS++  LKS VG S  SK+YDS
Sbjct: 177  SAS---------SSKGNTNQVSKEGSKPENEDSDDEKPLSSRFPLKSGVGES-TSKAYDS 226

Query: 1921 DEDKPLVAKINQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNK 1742
            D+DKPL  K+  NGSA+RD    K S M +KRP  +IKS+ Q  VKK KLS+ + P N K
Sbjct: 227  DDDKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVTAPTNKK 286

Query: 1741 QASVKAEPKVE-DDDDHVPISQRMKKPATADKKSSAVKNITXXXXXXXXXXXXXXXXXXX 1565
            QASVK EPK E DDDDH+PISQR+KK  T++ KSS++K  T                   
Sbjct: 287  QASVKPEPKAEDDDDDHLPISQRIKKSPTSESKSSSIKKTTKVVSSSVKKVNKKSKKVMK 346

Query: 1564 XXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATM 1385
                     VPP SGEG+KW  L HNGVIFPPPY+PHG+K+LYKGKPV+LTPEQEEVATM
Sbjct: 347  NSKYSKSSKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPEQEEVATM 406

Query: 1384 FAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXXXXXXXXX 1205
            FAVMLDT+YM+KP+FKENF  DW+KILGKNH+IQNLE+CDFSPIYEWHQ           
Sbjct: 407  FAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKEKKKQMTT 466

Query: 1204 XXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSD 1025
                           KYMWA V+G KEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRP D
Sbjct: 467  EEKKALKEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPCD 526

Query: 1024 ITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQS 845
            ITINIGK APIPECP+PGERWKE+RHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKG S
Sbjct: 527  ITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGLS 586

Query: 844  DKEKYEKSRLLKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEAD 665
            DKEKYEK+RLLKDYIQGIRAAYTKDFASKD TKKQIAVATYLIDKLALRAGNEKDDDEAD
Sbjct: 587  DKEKYEKARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNEKDDDEAD 646

Query: 664  TVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIF 485
            TVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEVEVE AVFKAIQQFRSGK+   D+F
Sbjct: 647  TVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGKEGSSDLF 706

Query: 484  DKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEV 305
            D LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLSRETKGGDVAE VVVYQHANKEV
Sbjct: 707  DLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSRETKGGDVAEKVVVYQHANKEV 766

Query: 304  AIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKS--ADGKPKR 131
            AIICNHQRTVSKSHSAQMLRLNEKIEELK V+EEL +DLSR KKGKPPLKS  ADGKPKR
Sbjct: 767  AIICNHQRTVSKSHSAQMLRLNEKIEELKAVVEELKSDLSRVKKGKPPLKSKNADGKPKR 826

Query: 130  NLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            NLNPE+LEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY
Sbjct: 827  NLNPESLEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 869


>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score = 1056 bits (2732), Expect = 0.0
 Identities = 575/868 (66%), Positives = 639/868 (73%), Gaps = 12/868 (1%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAV+AC K K+        EPLVFKR                      +D Q GR + DV
Sbjct: 1    MAVQACVKEKMMDEIDEDDEPLVFKRSNATSKHNQLNSDTKKSSQR--YDGQSGRQVSDV 58

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANL----RPSA 2222
               S NG+SS   KGK                 +AS S AKA P+  P+ +     R   
Sbjct: 59   P--STNGQSSSASKGKTTKLSSMKSPIASP---KASTSFAKASPVANPKVSSSSDDRSKH 113

Query: 2221 TYRSDNVNRPMKVGKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXSR 2042
            + + + +N  +K  K L+  AAEP    DSED+KPLSARL TGL              S 
Sbjct: 114  SSKQNTIN-VVKEEKELVNPAAEPYG--DSEDEKPLSARLFTGLTKGSSNNANKGLINSS 170

Query: 2041 LGQKPSIPKQE------DSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNG 1880
                P +PK E      DSDDE PLS+K +LK+N GTS   KSY+SD++K LV+   QNG
Sbjct: 171  PASLP-VPKPEINRYSDDSDDEIPLSSKFRLKANAGTSTV-KSYESDDNKTLVSNFQQNG 228

Query: 1879 SALRDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVED-D 1703
            S  R S S   S  ++KRP  E+KS+ QS VKK KLS+AS P+NNKQAS KAEPK +D D
Sbjct: 229  SINRGSKS---SIKVNKRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKADDSD 285

Query: 1702 DDHVPISQRMKKPATADKKSSAVKN-ITXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPG 1526
            DDHVPISQRMKK AT+  KSS  K  +T                            VPP 
Sbjct: 286  DDHVPISQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSKSSKVPPS 345

Query: 1525 SGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEYMSKP 1346
            SGEG+KW TL+HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQEEVATMFAVMLDT+YM+K 
Sbjct: 346  SGEGKKWNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMTKS 405

Query: 1345 KFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXX 1166
            KFKENFM DWRKILGKNH+IQNLEDCDF+PIYEWHQ                        
Sbjct: 406  KFKENFMDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEERLKQ 465

Query: 1165 XXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPE 986
              KYMWAIVNGVKEKVGNFRVEPP LFRGRGEHPKMGKLK+ IRPSDITINIGK APIPE
Sbjct: 466  EEKYMWAIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIPE 525

Query: 985  CPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSRLLKD 806
            CPIPGE WKEIRHDNTVTWLAFWNDPI P+EFKYVFLAASS+LKGQSDKEKYEK+RLLKD
Sbjct: 526  CPIPGESWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLKD 585

Query: 805  YIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 626
            +IQGIRAAYTKDFASKD+TK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE
Sbjct: 586  FIQGIRAAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 645

Query: 625  PIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLK 446
            P PP+ILKFDFLGKDSIRYQNEVEVE  V+KAIQQFR+GK+ GDD+FDKLDTSKLNAHLK
Sbjct: 646  PKPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNAHLK 705

Query: 445  ELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRTVSKS 266
             LMPGLTAKVFRTYNASITLDEMLSRETKGG+VAE +VVYQHANKEVAIICNHQRTVSKS
Sbjct: 706  GLMPGLTAKVFRTYNASITLDEMLSRETKGGNVAEKIVVYQHANKEVAIICNHQRTVSKS 765

Query: 265  HSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKIAQTN 86
            H AQM RLN KI+ELKG+L+ L TDL+RAKKGKPPL+ ADGKPKRNL PEALE+KI QTN
Sbjct: 766  HPAQMTRLNGKIDELKGILDGLQTDLARAKKGKPPLEDADGKPKRNLTPEALERKIGQTN 825

Query: 85   AKIEKMERDKETKEDLKTVALGTSKINY 2
            AKIEKMERDKETKE LKT+ALGTSKI+Y
Sbjct: 826  AKIEKMERDKETKEGLKTIALGTSKISY 853


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score = 1046 bits (2704), Expect = 0.0
 Identities = 567/889 (63%), Positives = 633/889 (71%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+   L         P++FKR                       D Q      DV
Sbjct: 1    MAVEACTT-NLMEDMEDDGGPVIFKRSKPAPKQNQANSEKKKLSLQK-QDGQSAVHTSDV 58

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG+SS  QKG++               P+ASNSSAKA P+  P AN +PSA    
Sbjct: 59   --RPANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATS 116

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP + +A   ++S+ S+D+KPLSAR                  
Sbjct: 117  TAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGG 176

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK+ QNGSA 
Sbjct: 177  DSCSIRRPVIEESEDSEDEKPLSCRFTSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSAS 235

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHV 1691
            RD    K +++ +KRP  E KS  QS VKK KLS+    I+NKQA+VK EPK EDDDD++
Sbjct: 236  RDGPMNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAAVKPEPKAEDDDDNI 295

Query: 1690 PISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXXXX 1586
            P+SQR KK                         PA+  K S  VK  +            
Sbjct: 296  PLSQRGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKKASTVVSSSLKKVNK 355

Query: 1585 XXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPE 1406
                            VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYK +P+ LTPE
Sbjct: 356  NSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPE 415

Query: 1405 QEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXX 1226
            QEEVATMFAVMLDT+YM+KP FKENF SDW+KILGKNH+IQNLEDCDF PIYEWHQ    
Sbjct: 416  QEEVATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDCDFGPIYEWHQQEKE 475

Query: 1225 XXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1046
                                  KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK
Sbjct: 476  KKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 535

Query: 1045 RRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAAS 866
            +RIRP DITINIGK APIPECPIPGERWKE+R+ NTVTWLA+WNDPIN KEFKYVFLAAS
Sbjct: 536  KRIRPRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDPINQKEFKYVFLAAS 595

Query: 865  STLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGN 689
            STLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGN
Sbjct: 596  STLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGN 655

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEV+VEPAVFKAIQQFRSG
Sbjct: 656  EKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFRSG 715

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG+VAENVVV
Sbjct: 716  KEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAENVVV 775

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K A
Sbjct: 776  YQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPTKGA 835

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DGK KRNLNPEALE+KI QTNAKIEKMERDKETKEDLKTVALGTSKINY
Sbjct: 836  DGKAKRNLNPEALERKITQTNAKIEKMERDKETKEDLKTVALGTSKINY 884


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score = 1045 bits (2701), Expect = 0.0
 Identities = 563/892 (63%), Positives = 637/892 (71%), Gaps = 36/892 (4%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+   L         P++FKR                        R +G+    V
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSL----QRHVGQSA--V 54

Query: 2389 H---VRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA- 2222
            H   VR  NG++S  QKG++               P+ASNSSAKA P+    AN +PSA 
Sbjct: 55   HTSDVRPANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAGANSKPSAS 114

Query: 2221 ---TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXX 2060
               T +  N ++        KP + +A   ++S+ S+D+KPLSAR               
Sbjct: 115  ATSTAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANK 174

Query: 2059 XXXXSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNG 1880
                S   ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK+  NG
Sbjct: 175  EGGDSCSIRRPVIEESEDSEDEKPLSRRFTSKSSLGES-TSKSYDSDEKKPLAAKVQPNG 233

Query: 1879 SALRDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDD 1700
            SA RDS   K +++ +KRP  E+KS  QS +KK KLS+    I+NKQA+VK EPK EDDD
Sbjct: 234  SASRDSPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDD 293

Query: 1699 DHVPISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXX 1595
            D++P+SQR KK                         PA+  K S+ VK  +         
Sbjct: 294  DNIPLSQRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKK 353

Query: 1594 XXXXXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNL 1415
                               VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYK +P+ L
Sbjct: 354  VNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITL 413

Query: 1414 TPEQEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQX 1235
            TPEQEEVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCDF PIYEWHQ 
Sbjct: 414  TPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQ 473

Query: 1234 XXXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMG 1055
                                     KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMG
Sbjct: 474  EKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMG 533

Query: 1054 KLKRRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFL 875
            KLK+RIRP DITINIGK APIPECPIPGERWKE+R+DNTVTWLA+WNDPIN KEFKYVFL
Sbjct: 534  KLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFL 593

Query: 874  AASSTLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALR 698
            AASSTLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALR
Sbjct: 594  AASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALR 653

Query: 697  AGNEKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQF 518
            AGNEKDDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEV+VEPAVFKAIQQF
Sbjct: 654  AGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQF 713

Query: 517  RSGKKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAEN 338
            RSGK+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS++T GG+VAE 
Sbjct: 714  RSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEK 773

Query: 337  VVVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPL 158
            VVVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKP  
Sbjct: 774  VVVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLS 833

Query: 157  KSADGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            K ADGKPKRNLNPEALE+KIAQTNAKIEKMERDKETKEDLKTVALGTSKINY
Sbjct: 834  KGADGKPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 885


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score = 1045 bits (2701), Expect = 0.0
 Identities = 562/889 (63%), Positives = 634/889 (71%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+   L         P++FKR                      H  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQK-HVGQSAVHTSDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG++S  QKG++               P+ASNSSAKA P+  P AN +PSA    
Sbjct: 60   --RPANGENSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATS 117

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP + +A   ++S+ S+D+KPLSAR                  
Sbjct: 118  TAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGG 177

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK+  NGSA 
Sbjct: 178  DSCSIRRPVIEESEDSEDEKPLSRRFTSKSSLGES-TSKSYDSDEKKPLAAKVQPNGSAS 236

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHV 1691
            RDS   K +++ +KRP  E+KS  QS +KK KLS+    I+NKQA+VK EPK EDDDD++
Sbjct: 237  RDSPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNI 296

Query: 1690 PISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXXXX 1586
            P+SQR KK                         PA+  K S+ VK  +            
Sbjct: 297  PLSQRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNK 356

Query: 1585 XXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPE 1406
                            VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYK +P+ LTPE
Sbjct: 357  KSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPE 416

Query: 1405 QEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXX 1226
            QEEVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCDF PIYEWHQ    
Sbjct: 417  QEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKE 476

Query: 1225 XXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1046
                                  KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK
Sbjct: 477  KKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 536

Query: 1045 RRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAAS 866
            +RIRP DITINIGK APIPECPIPGERWKE+R+DNTVTWLA+WNDPIN KEFKYVFLAAS
Sbjct: 537  KRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKEFKYVFLAAS 596

Query: 865  STLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGN 689
            STLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGN
Sbjct: 597  STLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGN 656

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEV+VEPAVFKAI QFRSG
Sbjct: 657  EKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIHQFRSG 716

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS++T GG+VAE VVV
Sbjct: 717  KEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKKTNGGEVAEKVVV 776

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKP  K A
Sbjct: 777  YQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPLSKGA 836

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DGKPKRNLNPEALE+KIAQTNAKIEKMERDKETKEDLKTVALGTSKINY
Sbjct: 837  DGKPKRNLNPEALERKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 885


>gb|EYU30724.1| hypothetical protein MIMGU_mgv1a001121mg [Erythranthe guttata]
          Length = 883

 Score = 1039 bits (2687), Expect = 0.0
 Identities = 549/812 (67%), Positives = 621/812 (76%), Gaps = 4/812 (0%)
 Frame = -2

Query: 2425 HDRQLGRPMPDVHVRSQNGKSSVVQKGKM--AXXXXXXXXXXXXXXPEASNSSAKAYPLM 2252
            H+ Q+GR   DV  R QNG ++  QKGK   +              P++SNSS KA P+ 
Sbjct: 48   HNAQVGRQSSDV--RPQNGTNANAQKGKSVTSSSSMKPPVRPSLVSPKSSNSSVKASPIK 105

Query: 2251 PPEANLRPSATYRSDNVNRPMKVGKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXX 2072
             P+ N +PS +   ++ +         + S  +  +S+DSEDDKPLSAR   G       
Sbjct: 106  SPDVNSKPSTSVVGESKS---------VKSTIKEENSEDSEDDKPLSARQVAG-SSKNNP 155

Query: 2071 XXXXXXXXSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVA-K 1895
                      LG+K ++PK EDSDDE PLS K Q KSN G S  S+S  S+E KPLVA K
Sbjct: 156  NQTNKPNAPNLGKKSNVPKPEDSDDEIPLSAKFQGKSNAGAS-TSRSSHSEEKKPLVARK 214

Query: 1894 INQNGSALRDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPK 1715
             ++NGSA   S+ +KPST+L KRPA  + SAGQS +KK KLS+ S+   +K+ASVK E K
Sbjct: 215  PDKNGSA---STERKPSTVLQKRPADGVASAGQSNLKKPKLSD-SLASKDKKASVKPEVK 270

Query: 1714 VEDDDDHVPISQRMKKPATADKKSS-AVKNITXXXXXXXXXXXXXXXXXXXXXXXXXXXX 1538
             EDD+D VP+SQR KK  T +KK S A+K                               
Sbjct: 271  AEDDEDLVPLSQRTKKSTTPEKKPSPALKTNNKTNSKTNSKTNKKSKQVSKDNNYSKSSK 330

Query: 1537 VPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEY 1358
            +PP SG+GQKWTTL+HNGVIFPPPY+PHGVK+LYKGKPVNLTPEQEEVATM+AVML+T+Y
Sbjct: 331  LPPSSGDGQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVNLTPEQEEVATMYAVMLETDY 390

Query: 1357 MSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXXXXXXXXXXXXXXXXXX 1178
            + KP+FKENFM+DW+KILGKNH+IQ+LE CDF+PIYEWHQ                    
Sbjct: 391  LKKPQFKENFMTDWKKILGKNHVIQSLEHCDFTPIYEWHQREKEKKKQMSTDEKKALKEE 450

Query: 1177 XXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGA 998
                  KYMWA+++GV+EKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIG+ A
Sbjct: 451  KLKLEEKYMWAVLDGVREKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGRDA 510

Query: 997  PIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSR 818
            PIPECPI GERWKEIRHDNTVTWLA+W+DPIN KEFKYVFLAASSTLKGQSDKEKYEK+R
Sbjct: 511  PIPECPIEGERWKEIRHDNTVTWLAYWSDPINGKEFKYVFLAASSTLKGQSDKEKYEKAR 570

Query: 817  LLKDYIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 638
            LLKDYIQGIR AYT+DF SKD  KKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 571  LLKDYIQGIRTAYTRDFVSKDPAKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 630

Query: 637  ENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLN 458
            ENVEP+PPNILKFDFLGKDSIRYQNEVEVE AVFKAIQQFRSGKK GDD+FDKLDTSKLN
Sbjct: 631  ENVEPVPPNILKFDFLGKDSIRYQNEVEVETAVFKAIQQFRSGKKGGDDLFDKLDTSKLN 690

Query: 457  AHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRT 278
            AHLKELMPGLTAKVFRTYNASITLD+ LSRETKGGD+AE VV Y HANKEVAIICNHQRT
Sbjct: 691  AHLKELMPGLTAKVFRTYNASITLDDKLSRETKGGDLAEKVVTYNHANKEVAIICNHQRT 750

Query: 277  VSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKI 98
            VSK+HSAQMLRL+EKI+ELKGVLEEL TDL RA+KGKP L  ADGK KRN+NPEALE+KI
Sbjct: 751  VSKTHSAQMLRLDEKIDELKGVLEELKTDLGRARKGKPLLAGADGKAKRNINPEALERKI 810

Query: 97   AQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            AQT AKIEKMERDKETKEDLKTVALGTSKINY
Sbjct: 811  AQTTAKIEKMERDKETKEDLKTVALGTSKINY 842


>dbj|BAG31375.1| topoisomerase I [Ophiorrhiza japonica]
          Length = 927

 Score = 1037 bits (2682), Expect = 0.0
 Identities = 563/891 (63%), Positives = 632/891 (70%), Gaps = 35/891 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+ P L         P++FKR                      H  Q      DV
Sbjct: 1    MAVEACT-PNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQK-HVGQSAVHTSDV 58

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG+SS  QKG++               P+ASNSSAKA P+  P AN +PSA    
Sbjct: 59   --RPANGESSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASATS 116

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP + +A   ++S+ S+D+KPLSAR                  
Sbjct: 117  TAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKEGG 176

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++  I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK+ QNGS  
Sbjct: 177  DSCSIRRRVIEESEDSEDEKPLSRRFTSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSVS 235

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEP--KVEDDDD 1697
            RD    K +++ +KRP  E+KS  QS VKK KLS+    I+NKQA+VK EP  K EDDDD
Sbjct: 236  RDGPMNKSASLSNKRPPGEVKSLNQSSVKKPKLSSPITSISNKQAAVKPEPEPKAEDDDD 295

Query: 1696 HVPISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXX 1592
            ++P+SQR KK                         PA+  K S+ VK  +          
Sbjct: 296  NIPLSQRGKKSQAATSKPKDEDDDNVPIAQRIKKSPASVSKSSAPVKKASTVVSPSLKKV 355

Query: 1591 XXXXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLT 1412
                              VPPGSGEGQKWTTL+HNGVIFPPPY PHGVK+LYK +P+ LT
Sbjct: 356  NKNSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYNPHGVKMLYKRQPITLT 415

Query: 1411 PEQEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXX 1232
            PEQEEVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCDF PIYEWHQ  
Sbjct: 416  PEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQE 475

Query: 1231 XXXXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGK 1052
                                    KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGK
Sbjct: 476  KEKKKQMTTEEKKALKEDKLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGK 535

Query: 1051 LKRRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLA 872
            LK+RIRP DITINIGK APIPECPIPGERWKE+R+DNTVTWLAFW DPIN KEFKYVFLA
Sbjct: 536  LKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWIDPINQKEFKYVFLA 595

Query: 871  ASSTLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRA 695
            ASSTLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRA
Sbjct: 596  ASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRA 655

Query: 694  GNEKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFR 515
            GNEKDDDEADTVGCCTLKVENVEP+PPNILKFDFLGKDSIRYQNEV+VEPAVFKAIQQFR
Sbjct: 656  GNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQVEPAVFKAIQQFR 715

Query: 514  SGKKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENV 335
            SGK+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG+VAE V
Sbjct: 716  SGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGEVAEKV 775

Query: 334  VVYQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLK 155
            VVYQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  +EEL TDLSR KKGKPP K
Sbjct: 776  VVYQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTAMEELKTDLSRVKKGKPPSK 835

Query: 154  SADGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
             ADGKPKRNLNPEALE+K+AQ NAKIEKMERDKETKEDLKTVALGTSKINY
Sbjct: 836  GADGKPKRNLNPEALERKMAQINAKIEKMERDKETKEDLKTVALGTSKINY 886


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score = 1025 bits (2651), Expect = 0.0
 Identities = 554/889 (62%), Positives = 628/889 (70%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+ P L         P++FKR                      H  Q      DV
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQK-HVGQSAVHTSDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG+SS  QKG++               P+ASNSSAKA P+  P AN + SA    
Sbjct: 60   --RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATS 117

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP + +A   ++S+ S+D+KPL AR S                
Sbjct: 118  TAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGG 177

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL  K+ QNGSA 
Sbjct: 178  DSCSIRRPVIEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLATKVQQNGSAS 236

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHV 1691
            RD    K +++L+KR   E+KS  QS +KK KLS+    I+NKQA+VK EPK EDDDD++
Sbjct: 237  RDGPMNKSASLLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAAVKPEPKAEDDDDNI 296

Query: 1690 PISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXXXX 1586
            P+SQR KK                         PA+  K S+ VK  +            
Sbjct: 297  PLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNK 356

Query: 1585 XXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPE 1406
                            VPPGSGEGQKWTTL+HNGV+F PPY+PHGVK+LYK +P+ LTPE
Sbjct: 357  KSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKXQPLTLTPE 416

Query: 1405 QEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXX 1226
            QEEVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH +QNLEDCDF PIYEWHQ    
Sbjct: 417  QEEVATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKE 476

Query: 1225 XXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1046
                                  KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK
Sbjct: 477  KRKQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 536

Query: 1045 RRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAAS 866
            +RIRP DITINIGK APIPECPIPGERWKE+R+DNTVTWLAFWNDPIN KE KYVFLAAS
Sbjct: 537  KRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDPINQKECKYVFLAAS 596

Query: 865  STLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGN 689
            STLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGN
Sbjct: 597  STLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGN 656

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSG
Sbjct: 657  EKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSG 716

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+   D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V V
Sbjct: 717  KEGCADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGV 776

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K A
Sbjct: 777  YQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPAKGA 836

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DG+PKRNLNPE+LE+KIAQTNAKIEKMERDK+TKEDLK VAL TSKI+Y
Sbjct: 837  DGEPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISY 885


>dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]
          Length = 920

 Score = 1021 bits (2640), Expect = 0.0
 Identities = 552/889 (62%), Positives = 625/889 (70%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+ P L         P++FKR                      H  Q      DV
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQK-HVGQSAVHTSDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG+SS  QKG++               P+ASNSSAKA P+  P AN + SA    
Sbjct: 60   --RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATS 117

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP + +A   ++S+ S+D+KPL AR S                
Sbjct: 118  TAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGG 177

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK+  NGSA 
Sbjct: 178  DSCSIRRPVIEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQPNGSAS 236

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHV 1691
            RD    K +++ +KR   E+KS  QS +KK KLS+    I+NKQA+VK EPK EDDDD++
Sbjct: 237  RDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNI 296

Query: 1690 PISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXXXX 1586
            P+SQR KK                         PA+  K S+ VK  +            
Sbjct: 297  PLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNK 356

Query: 1585 XXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPE 1406
                            VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYK +P+ LTPE
Sbjct: 357  KSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPITLTPE 416

Query: 1405 QEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXX 1226
            QEEVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCDF PIYEWHQ    
Sbjct: 417  QEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQEKE 476

Query: 1225 XXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1046
                                  KYMW IV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK
Sbjct: 477  KKKQMTTEEKKALKEERLQQEEKYMWVIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLK 536

Query: 1045 RRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAAS 866
            +RIRP DITINIGK APIPECPIPGERWKE+R+DNTVTWLA+WNDPIN KE KYVFL AS
Sbjct: 537  KRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPINQKERKYVFLGAS 596

Query: 865  STLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGN 689
            STLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGN
Sbjct: 597  STLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGN 656

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSG
Sbjct: 657  EKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSG 716

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+   D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V V
Sbjct: 717  KEGSADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGV 776

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K A
Sbjct: 777  YQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGA 836

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DG+PKRNLNPEALE+KIAQTNAKIEKME DK+TKEDLK VAL TSKI+Y
Sbjct: 837  DGEPKRNLNPEALERKIAQTNAKIEKMEGDKKTKEDLKAVALSTSKISY 885


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score = 1020 bits (2638), Expect = 0.0
 Identities = 550/889 (61%), Positives = 627/889 (70%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+ P L         P++FKR                      H  Q      DV
Sbjct: 1    MAVEACTTPNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQK-HVGQSAVHTSDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG+SS  QKG++               P+ASNSSAKA P+  P AN + SA    
Sbjct: 60   --RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATS 117

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP + +A   ++S+ S+D+KPL AR S                
Sbjct: 118  TAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGG 177

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++P I + EDS+DEKPLS +   KS++G S  SKS+DSDE KPL AK+ QNGSA 
Sbjct: 178  DSCSIRRPVIEESEDSEDEKPLSRRFPSKSSLGES-TSKSHDSDEKKPLAAKVQQNGSAS 236

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHV 1691
            RD    K +++ +KR   E+KS  QS +KK KLS+    I+NKQA+VK EPK EDDDD++
Sbjct: 237  RDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSTITSISNKQAAVKPEPKAEDDDDNI 296

Query: 1690 PISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXXXX 1586
            P+SQR KK                         PA+  K S+ VK  +            
Sbjct: 297  PLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNK 356

Query: 1585 XXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPE 1406
                            VPPGSGEGQKWTTL+HNGV+FPPPY+PHGVK+LYK +P+ LTPE
Sbjct: 357  KSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPE 416

Query: 1405 QEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXX 1226
            QEEVATMFA MLDT+YM+KP+FKENF SDW+KILGKNH IQNLEDCDF PIYEWHQ    
Sbjct: 417  QEEVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKE 476

Query: 1225 XXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1046
                                  KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK
Sbjct: 477  KKKQMTTEEKKALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLK 536

Query: 1045 RRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAAS 866
            +RIRP DITINIGK APIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLAAS
Sbjct: 537  KRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAAS 596

Query: 865  STLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGN 689
            STLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQ+AVATYLIDKLALRAGN
Sbjct: 597  STLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAVATYLIDKLALRAGN 656

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSG
Sbjct: 657  EKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSG 716

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V V
Sbjct: 717  KEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGV 776

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQ ANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K  
Sbjct: 777  YQRANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGD 836

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DG+PKRNLNPEALE+KIAQTNAKIEKMERDK+TKEDLK VAL TSKI+Y
Sbjct: 837  DGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISY 885


>dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score = 1018 bits (2631), Expect = 0.0
 Identities = 549/889 (61%), Positives = 625/889 (70%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+   L         P++FKR                      H  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQK-HVGQSAVHTSDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG+SS  QKG++               P+ASNSSAKA P+  P AN + SA    
Sbjct: 60   --RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATS 117

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP +  A   ++S+ S+D+KPL AR S                
Sbjct: 118  TAKQQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGG 177

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++P + + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK+ QNGSA 
Sbjct: 178  DSCSIRRPVVEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSAS 236

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHV 1691
            RD    K +++ +KR   E+KS  QS +KK KLS+    I+NKQA+VK EPK EDDDD++
Sbjct: 237  RDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNI 296

Query: 1690 PISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXXXX 1586
            P+SQR KK                         PA+  K S+ VK  +            
Sbjct: 297  PLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNK 356

Query: 1585 XXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPE 1406
                            VPPGSGEGQKWTTL+HNGVIFPPPY+PHGVK+LYK +P+ LTPE
Sbjct: 357  KSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYKRQPLTLTPE 416

Query: 1405 QEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXX 1226
            QEEVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH IQNLEDCDF PIYEWHQ    
Sbjct: 417  QEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDCDFGPIYEWHQQERE 476

Query: 1225 XXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1046
                                  KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK
Sbjct: 477  KKKQMTTEEKKALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLK 536

Query: 1045 RRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAAS 866
            +RI P DITINIGK APIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLA S
Sbjct: 537  KRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPS 596

Query: 865  STLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGN 689
            STLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGN
Sbjct: 597  STLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGN 656

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTL+VENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSG
Sbjct: 657  EKDDDEADTVGCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSG 716

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V V
Sbjct: 717  KEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGV 776

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K  
Sbjct: 777  YQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGD 836

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DG+PKRNLNPEALE+KIAQTNAKIEKMERDK+TKEDLK VAL TSKI+Y
Sbjct: 837  DGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISY 885


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score = 1017 bits (2630), Expect = 0.0
 Identities = 549/889 (61%), Positives = 624/889 (70%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+   L         P++FKR                      H  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQK-HVGQSAVHTSDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG+SS  QKG++               P+ASNSSAKA P+  P AN + SA    
Sbjct: 60   --RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATS 117

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP +  A   ++S+ S+D+KPL AR S                
Sbjct: 118  TAKQQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGG 177

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++P + + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK+ QNGSA 
Sbjct: 178  DSCSIRRPVVEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSAS 236

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHV 1691
            RD    K +++ +KR   E+KS  QS +KK KLS+    I+NKQA+VK EPK EDDDD++
Sbjct: 237  RDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNI 296

Query: 1690 PISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXXXX 1586
            P+SQR KK                         PA+  K S+ VK  +            
Sbjct: 297  PLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNK 356

Query: 1585 XXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPE 1406
                            VPPGSGEGQKWTTL+HNGV+FPPPY+PHGVK+LYK +P+ LTPE
Sbjct: 357  KSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPE 416

Query: 1405 QEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXX 1226
            QEEVATMFA MLDT+YM+KP+FKENF SDW+KILGKNH IQNLEDCDF PIYEWHQ    
Sbjct: 417  QEEVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQERE 476

Query: 1225 XXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1046
                                  KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK
Sbjct: 477  KKKQMTTEEKKALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLK 536

Query: 1045 RRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAAS 866
            +RI P DITINIGK APIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLA S
Sbjct: 537  KRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPS 596

Query: 865  STLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGN 689
            STLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGN
Sbjct: 597  STLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGN 656

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSG
Sbjct: 657  EKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSG 716

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V V
Sbjct: 717  KEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGV 776

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K  
Sbjct: 777  YQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGD 836

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DG+PKRNLNPEALE+KIAQTNAKIEKMERDK+TKEDLK VAL TSKI+Y
Sbjct: 837  DGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISY 885


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score = 1013 bits (2618), Expect = 0.0
 Identities = 546/889 (61%), Positives = 625/889 (70%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+   L         P++FKR                      H  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPTSKQNQANAEKKKLSLQK-HVGQSAVHTSDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG+SS  QKG++               P+ASNSSAKA P+  P AN + SA    
Sbjct: 60   --RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATS 117

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP + +A   ++S+ S+D+KPL AR S                
Sbjct: 118  TAKQQNHHKSSAAFIEPKPSVPAAKANSNSESSDDEKPLIARTSGCSSMGKSNHANKEGG 177

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++P I + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK+ QNGSA 
Sbjct: 178  DSCSIRRPVIEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSAS 236

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHV 1691
             +    K +++ +KR   E+KS  QS +KK KLS+    I+NKQA+VK EPK EDDDD++
Sbjct: 237  PEGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNI 296

Query: 1690 PISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXXXX 1586
            P+SQR KK                         P +  K S+ VK  +            
Sbjct: 297  PLSQRGKKSQTAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKKASTVVSTSLKKVNK 356

Query: 1585 XXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPE 1406
                            VPPGSGEGQKWTTL+HNGV+FPPPY+PHGVK+LYK +P+ LTPE
Sbjct: 357  KSKKVIRKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGVKMLYKRQPLTLTPE 416

Query: 1405 QEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXX 1226
            QEEVATMFAVMLDT+YM+KP+FKENF SDW+KILGKNH IQNLEDCDF PIYEWHQ    
Sbjct: 417  QEEVATMFAVMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDCDFGPIYEWHQQEKE 476

Query: 1225 XXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1046
                                  KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK
Sbjct: 477  KKKQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLK 536

Query: 1045 RRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAAS 866
            +RIRP DITINIGK APIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLAAS
Sbjct: 537  KRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNIKECKYVFLAAS 596

Query: 865  STLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGN 689
            STLKGQS KEKYEK+R+LKDYI GIRAAYTK F + KD  KKQIAVATYLIDKLALRAGN
Sbjct: 597  STLKGQSVKEKYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAVATYLIDKLALRAGN 656

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSG
Sbjct: 657  EKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSG 716

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG +AE V V
Sbjct: 717  KEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKIAEKVAV 776

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K A
Sbjct: 777  YQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKDA 836

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DG+PKRNLNPE+LE+KIAQTNAKIEKMERDK+TKEDLK VAL TSKI+Y
Sbjct: 837  DGEPKRNLNPESLERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISY 885


>dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]
          Length = 920

 Score = 1008 bits (2606), Expect = 0.0
 Identities = 546/889 (61%), Positives = 623/889 (70%), Gaps = 33/889 (3%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAVEAC+   L         P++FKR                      H  Q      DV
Sbjct: 1    MAVEACTTTNLMEDMEDDEGPVIFKRSNPASKQNQANSEKKKLSLQK-HVGQSAVHTSDV 59

Query: 2389 HVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSA---- 2222
              R  NG+SS  QKG++               P+ASNSSAKA P+  P AN + SA    
Sbjct: 60   --RPANGESSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASATS 117

Query: 2221 TYRSDNVNRPMKV---GKPLIGSAAEPNDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXX 2051
            T +  N ++        KP +  A   ++S+ S+D+KPL AR S                
Sbjct: 118  TAKQQNHHKSSAAFIEPKPSVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKEGG 177

Query: 2050 XSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGSAL 1871
             S   ++P + + EDS+DEKPLS +   KS++G S  SKSYDSDE KPL AK+ QNGSA 
Sbjct: 178  DSCSIRRPVVEESEDSEDEKPLSRRFPSKSSLGES-TSKSYDSDEKKPLAAKVQQNGSAS 236

Query: 1870 RDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDDHV 1691
            RD    K +++ +KR   E+KS  QS +KK KLS+    I+NKQA+VK EPK EDDDD++
Sbjct: 237  RDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAAVKPEPKAEDDDDNI 296

Query: 1690 PISQRMKK-------------------------PATADKKSSAVKNITXXXXXXXXXXXX 1586
            P+SQR KK                         PA+  K S+ VK  +            
Sbjct: 297  PLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKKASTVVSPSLKKVNK 356

Query: 1585 XXXXXXXXXXXXXXXXVPPGSGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPE 1406
                            VPPGSGEGQKWTTL+HNGV+F PPY+PHGVK+LYK +P+ LTPE
Sbjct: 357  KSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGVKMLYKQQPLTLTPE 416

Query: 1405 QEEVATMFAVMLDTEYMSKPKFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXX 1226
            QEEVATMFAVMLDT+YM+KP+FKENF SDW+K+LGKNH +QNLEDCDF PIYEWHQ    
Sbjct: 417  QEEVATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDCDFGPIYEWHQQEKE 476

Query: 1225 XXXXXXXXXXXXXXXXXXXXXXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 1046
                                  KYM AIV+GVKEKVGNFRVEPPGLFRGRGEHPK+GKLK
Sbjct: 477  KRKQMTTEEKKALKEERLQQEEKYMRAIVDGVKEKVGNFRVEPPGLFRGRGEHPKVGKLK 536

Query: 1045 RRIRPSDITINIGKGAPIPECPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAAS 866
            +RI P DITINIGK APIPECPIPGERWKE+R+DNTVTWLA+WNDP+N KE KYVFLA S
Sbjct: 537  KRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDPVNLKECKYVFLAPS 596

Query: 865  STLKGQSDKEKYEKSRLLKDYIQGIRAAYTKDFAS-KDLTKKQIAVATYLIDKLALRAGN 689
            STLKGQSDKEKYEK+RLLKDYI GIRAAYTKDF + KD  KKQIAVATYLIDKLALRAGN
Sbjct: 597  STLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAVATYLIDKLALRAGN 656

Query: 688  EKDDDEADTVGCCTLKVENVEPIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSG 509
            EKDDDEADTVGCCTLKVENVEP+PPNILK DF+GKDSIRYQNEV+VEPAVFKAIQQFRSG
Sbjct: 657  EKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQVEPAVFKAIQQFRSG 716

Query: 508  KKAGDDIFDKLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVV 329
            K+  +D+FD+LDTSKLNAHLKELMPGLTAKVFRTYNASITLD+MLS+ETKGG VAE V V
Sbjct: 717  KEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDMLSKETKGGKVAEKVGV 776

Query: 328  YQHANKEVAIICNHQRTVSKSHSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSA 149
            YQHANKEVAIICNHQRTVSKSHSAQM RLNEKI+ELK  LEEL TDLSRAKKGKPP K  
Sbjct: 777  YQHANKEVAIICNHQRTVSKSHSAQMSRLNEKIDELKTALEELKTDLSRAKKGKPPSKGD 836

Query: 148  DGKPKRNLNPEALEKKIAQTNAKIEKMERDKETKEDLKTVALGTSKINY 2
            DG+PKRNLNPEALE+KIAQTNAKIEKMERDK+TKEDLK VAL TSKI+Y
Sbjct: 837  DGEPKRNLNPEALERKIAQTNAKIEKMERDKKTKEDLKAVALSTSKISY 885


>ref|XP_010266803.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo nucifera]
          Length = 890

 Score =  995 bits (2573), Expect = 0.0
 Identities = 536/867 (61%), Positives = 619/867 (71%), Gaps = 10/867 (1%)
 Frame = -2

Query: 2572 IMAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPD 2393
            +MAV+AC KPK          P++FKR                       D   G+ + D
Sbjct: 1    MMAVDACIKPKFFDDGDDDEGPIIFKRNNASSKKNQLNKELKKVSSRK-RDGSSGKCVSD 59

Query: 2392 VHVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSATYR 2213
                S NG++S +QKGK                 +++ +S+KA   +  +    P     
Sbjct: 60   SF--SPNGQNSSLQKGKAVQSSKASTG-------KSTETSSKASTSITDKLKCSPQKNSS 110

Query: 2212 SDNVNRPMKVGKPLIGSAAEP-NDSDDSEDDKPLSARLSTGLXXXXXXXXXXXXXXSR-- 2042
             DN+ + +K  KP      EP  DS DS+DDKPLS RL T                S   
Sbjct: 111  IDNMEKQLK--KP----CNEPYTDSVDSDDDKPLSIRLPTSASLLKCKSSPVSKGLSSPV 164

Query: 2041 ----LGQKPSIPKQ---EDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQN 1883
                  +K ++  +   EDS+DE PLS K++LK +VG S   K YDS E+KPLV+K+ QN
Sbjct: 165  ASSSQSEKTNVTNKKSSEDSEDELPLSLKLKLKPSVGLS-GKKFYDSGEEKPLVSKLQQN 223

Query: 1882 GSALRDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDD 1703
            GS+ RD+   K    L+KRP S   S+GQSLVKK K+S  SVP   KQ S+K+EPK ED+
Sbjct: 224  GSSKRDNEPLKSPKNLNKRPLSGANSSGQSLVKKLKVSEVSVPTKVKQTSIKSEPKEEDE 283

Query: 1702 DDHVPISQRMKKPATADKKSSAVKNITXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPGS 1523
            DD +PISQR+KK A++D KS ++K  T                            +PP S
Sbjct: 284  DD-IPISQRLKKSASSDDKSLSLKKTTKVVSSSFKKTTNKLKKAAKNSKYSKSTKMPPSS 342

Query: 1522 GEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEYMSKPK 1343
            GEGQKWTTL HNGVIFPP Y+PHGVK+LY GKPV+LTPEQEEVATMFAVM DT+Y +K +
Sbjct: 343  GEGQKWTTLEHNGVIFPPLYKPHGVKMLYNGKPVDLTPEQEEVATMFAVMKDTDYATKSR 402

Query: 1342 FKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXX 1163
            F ENFM+DWR ILGKNH+I+  E CDF+PIYEWHQ                         
Sbjct: 403  FIENFMNDWRTILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSAEEKKALKEEKLKQE 462

Query: 1162 XKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPEC 983
             KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RI PSDITINIGKGAPIPEC
Sbjct: 463  EKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIHPSDITINIGKGAPIPEC 522

Query: 982  PIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSRLLKDY 803
            PIPGERWKE+RHDNTVTWLAFWNDPINPKEFKYVFLAASS+LKGQSDKEKYEK+RLLKDY
Sbjct: 523  PIPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDY 582

Query: 802  IQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP 623
            I+ IRA YT+DF SKD+TK+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 
Sbjct: 583  IKDIRANYTRDFVSKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEL 642

Query: 622  IPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLKE 443
            +PPN L+FDFLGKDSIRY N VEVE AV+KAI QF++GK+ G+D+FD LDTSKLNAHLKE
Sbjct: 643  VPPNKLQFDFLGKDSIRYFNTVEVELAVYKAIGQFKNGKEDGEDLFDSLDTSKLNAHLKE 702

Query: 442  LMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRTVSKSH 263
            LMPGLTAKVFRTYNASITLDEML+RE+KGGDVAE + VYQHANKEVAIICNHQR+VSKSH
Sbjct: 703  LMPGLTAKVFRTYNASITLDEMLNRESKGGDVAEKIAVYQHANKEVAIICNHQRSVSKSH 762

Query: 262  SAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKIAQTNA 83
            SAQM RL++KI+ELK  L+EL TDL+RAKKGKPPLK ADGKPKRNL PEALEKKIAQ NA
Sbjct: 763  SAQMHRLDDKIKELKDALDELKTDLARAKKGKPPLKGADGKPKRNLTPEALEKKIAQANA 822

Query: 82   KIEKMERDKETKEDLKTVALGTSKINY 2
            KIEKMERDK+ KEDLKTVALGTSKINY
Sbjct: 823  KIEKMERDKQIKEDLKTVALGTSKINY 849


>ref|XP_010252639.1| PREDICTED: DNA topoisomerase 1-like [Nelumbo nucifera]
          Length = 883

 Score =  988 bits (2553), Expect = 0.0
 Identities = 533/868 (61%), Positives = 620/868 (71%), Gaps = 12/868 (1%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXEPLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMPDV 2390
            MAV+AC KPK+         P VFKR                      +D   G+     
Sbjct: 1    MAVDACIKPKIIDDDDDDEGPAVFKRNNTASRKNQVNSELKKASSQR-NDGSSGK----- 54

Query: 2389 HVR---SQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSAT 2219
            HV    S NG++S +QKGK                 + + +S+ A   +  ++   P   
Sbjct: 55   HVSGSLSPNGQNSSLQKGKAVSKTSAG---------KPTAASSNASTSIADKSRCSPQKN 105

Query: 2218 YRSDNVNRPMKVGKPLIGSAAEPNDSDDSEDDKPLSARLST-GLXXXXXXXXXXXXXXSR 2042
               +N+ +  ++ KP  G   +P   DDS+DDKPLS RL+T G               S 
Sbjct: 106  LAINNMQK-QQLNKPCNGPKEDP---DDSDDDKPLSFRLATSGSSLKIKSQPGTKGHGSP 161

Query: 2041 LGQKPSIPKQE--------DSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQ 1886
            +     + K +        DS+DE PLS+K QLK+NVG+S   K YDSDE+KPL+ K  Q
Sbjct: 162  VPSSLQMDKTKITCKKSSADSEDEIPLSSKFQLKTNVGSSV--KKYDSDEEKPLIFKFQQ 219

Query: 1885 NGSALRDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVED 1706
            NGS+ +D+   K    L+KRP S++ ++GQSLVKK KLS  S+P   KQA +K+EPK ED
Sbjct: 220  NGSSKKDNELSKSLKSLNKRPMSDVNTSGQSLVKKPKLSE-SIPAKVKQAPIKSEPK-ED 277

Query: 1705 DDDHVPISQRMKKPATADKKSSAVKNITXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPG 1526
            D+D++PISQR+KK A +D KSS+ K  T                             PP 
Sbjct: 278  DEDNIPISQRLKKSAPSDNKSSSTKKTTTKVVSSSFKKTSKKLKKDKYSKSTKV---PPS 334

Query: 1525 SGEGQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEYMSKP 1346
            SGEGQKWTTL HNGVIFPPPY+PHGVK+LY G+PV+LTPEQEEVATMFAVM DTEY +K 
Sbjct: 335  SGEGQKWTTLEHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTEYATKQ 394

Query: 1345 KFKENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXX 1166
            KF ENFM+DW+ ILGKNH+I+  E CDF+PIYEWHQ                        
Sbjct: 395  KFVENFMNDWKVILGKNHVIKKFELCDFTPIYEWHQREKEKKKQMSAEEKKALKEEKLKQ 454

Query: 1165 XXKYMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPE 986
              KYMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRP+DITINIGKGAP+PE
Sbjct: 455  EEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGAPVPE 514

Query: 985  CPIPGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSRLLKD 806
            CPIPGERWKE++HDNTVTWLAFWNDPINPKEFKYVFLAASS+LKGQSDKEKYEK+RLLKD
Sbjct: 515  CPIPGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKD 574

Query: 805  YIQGIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 626
            YI+ IRA YT+DF+SKD+ K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE
Sbjct: 575  YIKDIRANYTRDFSSKDIAKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVE 634

Query: 625  PIPPNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLK 446
             IPPN L+FDFLGKDSIRY N VEVE  V+KAI QF+ GKK G+D+FDKLDTSKLNAHLK
Sbjct: 635  LIPPNKLQFDFLGKDSIRYFNTVEVELPVYKAIGQFKEGKKEGEDLFDKLDTSKLNAHLK 694

Query: 445  ELMPGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRTVSKS 266
            ELMPGLTAKVFRTYNASITLD ML++ETK GDVAE + VYQHANKEVAIICNHQR+VSKS
Sbjct: 695  ELMPGLTAKVFRTYNASITLDGMLNKETKDGDVAEKITVYQHANKEVAIICNHQRSVSKS 754

Query: 265  HSAQMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKIAQTN 86
            HSAQM RL++KI+ELK +L+EL TDL+RAKKGKPPLK ADGKPKRNL PEALE+KIAQ N
Sbjct: 755  HSAQMNRLDDKIKELKELLDELKTDLARAKKGKPPLKGADGKPKRNLTPEALERKIAQAN 814

Query: 85   AKIEKMERDKETKEDLKTVALGTSKINY 2
            AKIEKMERDK+ KEDLKTVALGTSKINY
Sbjct: 815  AKIEKMERDKQIKEDLKTVALGTSKINY 842


>ref|XP_009790344.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Nicotiana
            sylvestris]
          Length = 876

 Score =  976 bits (2522), Expect = 0.0
 Identities = 539/865 (62%), Positives = 613/865 (70%), Gaps = 9/865 (1%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXE--PLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMP 2396
            MAVEA SK KL        +  PLVFKR                       D + GR + 
Sbjct: 1    MAVEAFSKTKLMAEVDDDDDDMPLVFKRSTTSKQNQSNSSSQK-------QDGRSGRQVS 53

Query: 2395 DVHVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSATY 2216
            DV  RS NG++S  QK K                P+AS SS++    + P  N RPSA+ 
Sbjct: 54   DV--RSPNGQNSSAQKVKAGTSSKASPAVSPFTSPKASPSSSR----ISPAPNSRPSASA 107

Query: 2215 --RSDNVNRPMKV----GKPLIGSAAEPND-SDDSEDDKPLSARLSTGLXXXXXXXXXXX 2057
              ++ NVN+  K+     K  +   + PND ++DSEDDKPLSARLS+GL           
Sbjct: 108  GNQAKNVNQQSKIVPNEPKQAVEPKSGPNDEAEDSEDDKPLSARLSSGLSKSISSHANKV 167

Query: 2056 XXXSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGS 1877
               S   QK   PK+EDSDDE PL+++ QLKSN G S  SKS +S+E KP   KI QNG 
Sbjct: 168  LGTSASVQKSKPPKKEDSDDEIPLASRFQLKSNAGAS-TSKSSNSEEVKP---KIRQNGL 223

Query: 1876 ALRDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDD 1697
                  SK+P   +S     ++KS G  L+  H    +        ASVK E K EDDDD
Sbjct: 224  PSTTVLSKRPPGDVSLLLRLQLKSLG-FLMHLHLFRLSX-------ASVKPEKKTEDDDD 275

Query: 1696 HVPISQRMKKPATADKKSSAVKNITXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPGSGE 1517
             VPISQR+KK   +  K S+ K  T                              P SGE
Sbjct: 276  DVPISQRIKKSVASASKVSSTKKATKVVSSSMKTKKKLKKSKYSKSSKLQ-----PSSGE 330

Query: 1516 GQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEYMSKPKFK 1337
            GQKWTTL+HNGVIFPP Y+PHGVK+LYKGKP+NLTPEQEEVATM+AVMLDTEYMSKP+FK
Sbjct: 331  GQKWTTLVHNGVIFPPSYKPHGVKMLYKGKPINLTPEQEEVATMYAVMLDTEYMSKPQFK 390

Query: 1336 ENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXXK 1157
            ENFM+DWRKILGKNH+IQNL+DCDF+PIYEWHQ                          K
Sbjct: 391  ENFMNDWRKILGKNHVIQNLDDCDFTPIYEWHQSEKEKKKQMSTEEKKALREEKLKQEEK 450

Query: 1156 YMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPI 977
            YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRP+DITINIGKGAPIPECPI
Sbjct: 451  YMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGAPIPECPI 510

Query: 976  PGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSRLLKDYIQ 797
            PGERWKE+RHDNTVTWLAFWNDPINP+EFKYVFLAASS+LKGQSDKEKYEK+R LKDYI+
Sbjct: 511  PGERWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIE 570

Query: 796  GIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPIP 617
            GIR+AYTKDF SKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+P
Sbjct: 571  GIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 630

Query: 616  PNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLKELM 437
            PNILKFDFLGKDSIRYQNEV V   VFKAIQ FRSGKK GDD+FDKLDTSKLNAHLKELM
Sbjct: 631  PNILKFDFLGKDSIRYQNEVAVYEPVFKAIQLFRSGKKGGDDLFDKLDTSKLNAHLKELM 690

Query: 436  PGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRTVSKSHSA 257
            PGLTAKVFRTYNAS+TL++ L++ T+GG++AE V VY  ANKEVAIICNHQR+VSKSHS 
Sbjct: 691  PGLTAKVFRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSV 750

Query: 256  QMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKIAQTNAKI 77
            Q+ +LNEKI+ELK +LEE   DL+RAKKGKPPLK ADGK KRNL PEAL+KK+ QTNAKI
Sbjct: 751  QISKLNEKIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKMDQTNAKI 810

Query: 76   EKMERDKETKEDLKTVALGTSKINY 2
            E +E+  ETKE+LKTVALGTSKINY
Sbjct: 811  ENIEKQIETKEELKTVALGTSKINY 835


>ref|XP_009619726.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 1-like [Nicotiana
            tomentosiformis]
          Length = 877

 Score =  973 bits (2515), Expect = 0.0
 Identities = 540/865 (62%), Positives = 610/865 (70%), Gaps = 9/865 (1%)
 Frame = -2

Query: 2569 MAVEACSKPKLXXXXXXXXE--PLVFKRXXXXXXXXXXXXXXXXXXXXXKHDRQLGRPMP 2396
            MAVEA SK KL        +  PLVFKR                       D + GR   
Sbjct: 1    MAVEAFSKTKLMAEVDDDDDDMPLVFKRSSTTSKQNQSNSSSQK------QDGRSGRQAS 54

Query: 2395 DVHVRSQNGKSSVVQKGKMAXXXXXXXXXXXXXXPEASNSSAKAYPLMPPEANLRPSATY 2216
            DV  RS NG+SS  QK K                P+AS SS +      P  N RPSA+ 
Sbjct: 55   DV--RSPNGQSSSAQKVKAGTSSKASRAVSPFTSPKASPSSGRT----SPAPNSRPSASA 108

Query: 2215 --RSDNVNRPMKV----GKPLIGSAAEPND-SDDSEDDKPLSARLSTGLXXXXXXXXXXX 2057
              ++ +VN+  K+     K  +   +EPND ++DSEDDKPLSARLS+GL           
Sbjct: 109  GNQAKDVNQQSKIVPNEPKQAVEPKSEPNDEAEDSEDDKPLSARLSSGLSKSNSSHANKV 168

Query: 2056 XXXSRLGQKPSIPKQEDSDDEKPLSTKVQLKSNVGTSYASKSYDSDEDKPLVAKINQNGS 1877
               S   QK   PK+EDSDDE PL+++ QLKSN G S  SKS +S+E KP   KI QNG 
Sbjct: 169  LGTSASVQKSRPPKKEDSDDEIPLASRFQLKSNAGAS-TSKSSNSEEVKP---KIRQNGL 224

Query: 1876 ALRDSSSKKPSTMLSKRPASEIKSAGQSLVKKHKLSNASVPINNKQASVKAEPKVEDDDD 1697
                  SK+P   +S     ++KS G  L+  H    +        ASVK E K EDDDD
Sbjct: 225  PSTTVLSKRPPGDVSLLLRLQLKSLG-FLMHLHLFRVSX-------ASVKPEKKTEDDDD 276

Query: 1696 HVPISQRMKKPATADKKSSAVKNITXXXXXXXXXXXXXXXXXXXXXXXXXXXXVPPGSGE 1517
             VPISQR+KK   +  K S+ K  T                              P SGE
Sbjct: 277  DVPISQRIKKSVASASKLSSAKKATKVVSSSMKTKKKLKKSKYSKSSKLQ-----PSSGE 331

Query: 1516 GQKWTTLIHNGVIFPPPYQPHGVKILYKGKPVNLTPEQEEVATMFAVMLDTEYMSKPKFK 1337
            GQKWTTL+HNGVIFPPPY+PHGVK+LYKGKPV+LTPEQEEVATM+AVMLDT+YMSK +FK
Sbjct: 332  GQKWTTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMYAVMLDTDYMSKLQFK 391

Query: 1336 ENFMSDWRKILGKNHIIQNLEDCDFSPIYEWHQXXXXXXXXXXXXXXXXXXXXXXXXXXK 1157
            ENFM+DWRKILGKNH+IQNL+DCDF+PIYEWHQ                          K
Sbjct: 392  ENFMNDWRKILGKNHVIQNLDDCDFTPIYEWHQSEKEKKKQMSTEEKKALREEKLKQEEK 451

Query: 1156 YMWAIVNGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKGAPIPECPI 977
            YMWAIV+GVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRP+DITINIGKGAPIPECPI
Sbjct: 452  YMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPNDITINIGKGAPIPECPI 511

Query: 976  PGERWKEIRHDNTVTWLAFWNDPINPKEFKYVFLAASSTLKGQSDKEKYEKSRLLKDYIQ 797
            PGERWKE+RHDNTVTWLAFWNDPINP+EFKYVFLAASS+LKGQSDKEKYEK+R LKDYI+
Sbjct: 512  PGERWKEVRHDNTVTWLAFWNDPINPREFKYVFLAASSSLKGQSDKEKYEKARRLKDYIE 571

Query: 796  GIRAAYTKDFASKDLTKKQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPIP 617
            GIR+AYTKDF SKD  K+QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP+P
Sbjct: 572  GIRSAYTKDFTSKDPVKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVP 631

Query: 616  PNILKFDFLGKDSIRYQNEVEVEPAVFKAIQQFRSGKKAGDDIFDKLDTSKLNAHLKELM 437
            PNILKFDFLGKDSIRYQNEV V   VFKAIQ FRSGKK GDD+FDKLDTSKLNAHLKELM
Sbjct: 632  PNILKFDFLGKDSIRYQNEVAVYEPVFKAIQLFRSGKKGGDDLFDKLDTSKLNAHLKELM 691

Query: 436  PGLTAKVFRTYNASITLDEMLSRETKGGDVAENVVVYQHANKEVAIICNHQRTVSKSHSA 257
            PGLTAKVFRTYNAS+TL++ L++ T+GG++AE V VY  ANKEVAIICNHQR+VSKSHS 
Sbjct: 692  PGLTAKVFRTYNASVTLEQQLTKLTQGGELAEKVAVYNLANKEVAIICNHQRSVSKSHSV 751

Query: 256  QMLRLNEKIEELKGVLEELTTDLSRAKKGKPPLKSADGKPKRNLNPEALEKKIAQTNAKI 77
            Q+ +LNEKI+ELK +LEE   DL+RAKKGKPPLK ADGK KRNL PEAL+KKI QTN KI
Sbjct: 752  QISKLNEKIDELKALLEEFKVDLARAKKGKPPLKGADGKAKRNLAPEALQKKIDQTNVKI 811

Query: 76   EKMERDKETKEDLKTVALGTSKINY 2
            E +ER  ETKE+LKTVALGTSKINY
Sbjct: 812  ENIERQIETKEELKTVALGTSKINY 836