BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Forsythia21_contig00006194
         (828 letters)

Database: ./nr 
           69,698,275 sequences; 24,982,196,650 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_004250405.1| PREDICTED: receptor homology region, transme...   131   6e-28
ref|XP_006361369.1| PREDICTED: E3 ubiquitin-protein ligase RNF13...   130   8e-28
ref|XP_011074947.1| PREDICTED: receptor homology region, transme...   130   1e-27
ref|XP_011074946.1| PREDICTED: receptor homology region, transme...   130   1e-27
ref|XP_002269731.1| PREDICTED: receptor homology region, transme...   118   4e-24
emb|CDP18365.1| unnamed protein product [Coffea canephora]            112   3e-22
gb|KDO83895.1| hypothetical protein CISIN_1g013394mg [Citrus sin...   112   3e-22
gb|KDO83894.1| hypothetical protein CISIN_1g013394mg [Citrus sin...   112   3e-22
gb|KDO83893.1| hypothetical protein CISIN_1g013394mg [Citrus sin...   112   3e-22
gb|KDO83892.1| hypothetical protein CISIN_1g013394mg [Citrus sin...   112   3e-22
ref|XP_006473184.1| PREDICTED: E3 ubiquitin-protein ligase RNF13...   112   3e-22
ref|XP_006434599.1| hypothetical protein CICLE_v10001161mg [Citr...   112   3e-22
ref|XP_006434598.1| hypothetical protein CICLE_v10001161mg [Citr...   112   3e-22
ref|XP_006434597.1| hypothetical protein CICLE_v10001161mg [Citr...   112   3e-22
ref|XP_011001793.1| PREDICTED: receptor homology region, transme...   109   2e-21
ref|XP_011001792.1| PREDICTED: receptor homology region, transme...   109   2e-21
emb|CBI18269.3| unnamed protein product [Vitis vinifera]              109   2e-21
ref|XP_002325986.1| hypothetical protein POPTR_0019s11200g [Popu...   109   2e-21
ref|XP_012075161.1| PREDICTED: receptor homology region, transme...   108   4e-21
ref|XP_006353622.1| PREDICTED: E3 ubiquitin-protein ligase RNF13...   108   5e-21

>ref|XP_004250405.1| PREDICTED: receptor homology region, transmembrane domain- and RING
           domain-containing protein 2-like [Solanum lycopersicum]
          Length = 444

 Score =  131 bits (329), Expect = 6e-28
 Identities = 67/111 (60%), Positives = 73/111 (65%)
 Frame = +3

Query: 3   RPHSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPL 182
           RP SISSTPYN                   +DL+N SSQRSRA+YL+SPHSLGYPSLSPL
Sbjct: 332 RPQSISSTPYNHQSLQSYHQSPHLTISRSSLDLQNASSQRSRASYLISPHSLGYPSLSPL 391

Query: 183 NSRYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           NSRYMSPYIP              R PNPL +SES TSFSP+ASAQSLPGC
Sbjct: 392 NSRYMSPYIPSPGNASSSYIGSSSRHPNPLRHSESTTSFSPFASAQSLPGC 442


>ref|XP_006361369.1| PREDICTED: E3 ubiquitin-protein ligase RNF13-like [Solanum
           tuberosum]
          Length = 444

 Score =  130 bits (328), Expect = 8e-28
 Identities = 67/111 (60%), Positives = 74/111 (66%)
 Frame = +3

Query: 3   RPHSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPL 182
           RP SISSTPYN                   +DL+N+SSQRSRA+YL+SPHSLGYPSLSPL
Sbjct: 332 RPLSISSTPYNHQSLQSYHQSPHLSISRSSLDLQNVSSQRSRASYLISPHSLGYPSLSPL 391

Query: 183 NSRYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           NSRYMSPYIP              R PNPL +SES TSFSP+ASAQSLPGC
Sbjct: 392 NSRYMSPYIPSPGNASSSYIGSSSRHPNPLRHSESTTSFSPFASAQSLPGC 442


>ref|XP_011074947.1| PREDICTED: receptor homology region, transmembrane domain- and RING
           domain-containing protein 2-like isoform X2 [Sesamum
           indicum]
          Length = 368

 Score =  130 bits (326), Expect = 1e-27
 Identities = 67/111 (60%), Positives = 70/111 (63%)
 Frame = +3

Query: 3   RPHSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPL 182
           RP SIS TPYN                   VDLRNMSSQRS  AYLVSPHS+GYPSLSPL
Sbjct: 257 RPQSISGTPYNHHSLQSHHRSPHLNPSQSSVDLRNMSSQRSDGAYLVSPHSIGYPSLSPL 316

Query: 183 NSRYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           NSRY+SPYIP              RQPNPLHYS S  SFSP+ASA SLPGC
Sbjct: 317 NSRYLSPYIPSPGNASSSYVGSSSRQPNPLHYSGSPASFSPFASAHSLPGC 367


>ref|XP_011074946.1| PREDICTED: receptor homology region, transmembrane domain- and RING
           domain-containing protein 2-like isoform X1 [Sesamum
           indicum]
          Length = 442

 Score =  130 bits (326), Expect = 1e-27
 Identities = 67/111 (60%), Positives = 70/111 (63%)
 Frame = +3

Query: 3   RPHSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPL 182
           RP SIS TPYN                   VDLRNMSSQRS  AYLVSPHS+GYPSLSPL
Sbjct: 331 RPQSISGTPYNHHSLQSHHRSPHLNPSQSSVDLRNMSSQRSDGAYLVSPHSIGYPSLSPL 390

Query: 183 NSRYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           NSRY+SPYIP              RQPNPLHYS S  SFSP+ASA SLPGC
Sbjct: 391 NSRYLSPYIPSPGNASSSYVGSSSRQPNPLHYSGSPASFSPFASAHSLPGC 441


>ref|XP_002269731.1| PREDICTED: receptor homology region, transmembrane domain- and RING
           domain-containing protein 2-like [Vitis vinifera]
          Length = 446

 Score =  118 bits (296), Expect = 4e-24
 Identities = 63/111 (56%), Positives = 71/111 (63%)
 Frame = +3

Query: 3   RPHSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPL 182
           R +S+S+TPY                    +DLRN SSQRS A+YLVSPHS+GYPSLSPL
Sbjct: 337 RNNSLSATPY-IQQSLQSYRQSSLSVSRSSLDLRNASSQRSHASYLVSPHSMGYPSLSPL 395

Query: 183 NSRYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           NSRY+SPYIP              R P+PLHYSESATSFSPY SAQSLP C
Sbjct: 396 NSRYLSPYIPSPSNASLSYVGSSSRPPHPLHYSESATSFSPYTSAQSLPEC 446


>emb|CDP18365.1| unnamed protein product [Coffea canephora]
          Length = 433

 Score =  112 bits (280), Expect = 3e-22
 Identities = 63/113 (55%), Positives = 69/113 (61%), Gaps = 2/113 (1%)
 Frame = +3

Query: 3   RPHSISS-TPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPH-SLGYPSLS 176
           RP+SISS TPYN                   VDLRN SSQRS A+YL S H SLGYP LS
Sbjct: 321 RPNSISSSTPYNLQSLRSYNQSPHLSVSRSSVDLRNASSQRSHASYLFSSHHSLGYPPLS 380

Query: 177 PLNSRYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           PLNSR+MSPY+P              +QP+PLHYSESA SFSPY SA SLP C
Sbjct: 381 PLNSRFMSPYVPSPGNASSSYIGSSSQQPHPLHYSESAASFSPYTSAYSLPEC 433


>gb|KDO83895.1| hypothetical protein CISIN_1g013394mg [Citrus sinensis]
           gi|641865211|gb|KDO83896.1| hypothetical protein
           CISIN_1g013394mg [Citrus sinensis]
          Length = 296

 Score =  112 bits (280), Expect = 3e-22
 Identities = 56/109 (51%), Positives = 68/109 (62%)
 Frame = +3

Query: 9   HSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNS 188
           HS++STPY                    +DLR+ SSQRS  +Y++S HS+GYPS+SPLNS
Sbjct: 184 HSVASTPYIPQSLRSYCQSPPISVSRSSLDLRHASSQRSHGSYIMSSHSIGYPSISPLNS 243

Query: 189 RYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           RYMSPY+P               Q +PLHYSESATSFSP+ASAQSLP C
Sbjct: 244 RYMSPYLPSPSNASPSLVGSSSHQQHPLHYSESATSFSPFASAQSLPEC 292


>gb|KDO83894.1| hypothetical protein CISIN_1g013394mg [Citrus sinensis]
          Length = 370

 Score =  112 bits (280), Expect = 3e-22
 Identities = 56/109 (51%), Positives = 68/109 (62%)
 Frame = +3

Query: 9   HSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNS 188
           HS++STPY                    +DLR+ SSQRS  +Y++S HS+GYPS+SPLNS
Sbjct: 258 HSVASTPYIPQSLRSYCQSPPISVSRSSLDLRHASSQRSHGSYIMSSHSIGYPSISPLNS 317

Query: 189 RYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           RYMSPY+P               Q +PLHYSESATSFSP+ASAQSLP C
Sbjct: 318 RYMSPYLPSPSNASPSLVGSSSHQQHPLHYSESATSFSPFASAQSLPEC 366


>gb|KDO83893.1| hypothetical protein CISIN_1g013394mg [Citrus sinensis]
          Length = 444

 Score =  112 bits (280), Expect = 3e-22
 Identities = 56/109 (51%), Positives = 68/109 (62%)
 Frame = +3

Query: 9   HSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNS 188
           HS++STPY                    +DLR+ SSQRS  +Y++S HS+GYPS+SPLNS
Sbjct: 332 HSVASTPYIPQSLRSYCQSPPISVSRSSLDLRHASSQRSHGSYIMSSHSIGYPSISPLNS 391

Query: 189 RYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           RYMSPY+P               Q +PLHYSESATSFSP+ASAQSLP C
Sbjct: 392 RYMSPYLPSPSNASPSLVGSSSHQQHPLHYSESATSFSPFASAQSLPEC 440


>gb|KDO83892.1| hypothetical protein CISIN_1g013394mg [Citrus sinensis]
          Length = 419

 Score =  112 bits (280), Expect = 3e-22
 Identities = 56/109 (51%), Positives = 68/109 (62%)
 Frame = +3

Query: 9   HSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNS 188
           HS++STPY                    +DLR+ SSQRS  +Y++S HS+GYPS+SPLNS
Sbjct: 307 HSVASTPYIPQSLRSYCQSPPISVSRSSLDLRHASSQRSHGSYIMSSHSIGYPSISPLNS 366

Query: 189 RYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           RYMSPY+P               Q +PLHYSESATSFSP+ASAQSLP C
Sbjct: 367 RYMSPYLPSPSNASPSLVGSSSHQQHPLHYSESATSFSPFASAQSLPEC 415


>ref|XP_006473184.1| PREDICTED: E3 ubiquitin-protein ligase RNF13-like [Citrus sinensis]
          Length = 444

 Score =  112 bits (280), Expect = 3e-22
 Identities = 56/109 (51%), Positives = 68/109 (62%)
 Frame = +3

Query: 9   HSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNS 188
           HS++STPY                    +DLR+ SSQRS  +Y++S HS+GYPS+SPLNS
Sbjct: 332 HSVASTPYIPQSLRSYCQSPPISVSRSSLDLRHASSQRSHGSYIMSSHSIGYPSISPLNS 391

Query: 189 RYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           RYMSPY+P               Q +PLHYSESATSFSP+ASAQSLP C
Sbjct: 392 RYMSPYLPSPSNASPSLVGSSSHQQHPLHYSESATSFSPFASAQSLPEC 440


>ref|XP_006434599.1| hypothetical protein CICLE_v10001161mg [Citrus clementina]
           gi|557536721|gb|ESR47839.1| hypothetical protein
           CICLE_v10001161mg [Citrus clementina]
          Length = 444

 Score =  112 bits (280), Expect = 3e-22
 Identities = 56/109 (51%), Positives = 68/109 (62%)
 Frame = +3

Query: 9   HSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNS 188
           HS++STPY                    +DLR+ SSQRS  +Y++S HS+GYPS+SPLNS
Sbjct: 332 HSVASTPYIPQSLRSYCQSPPISVSQSSLDLRHASSQRSHGSYIMSSHSIGYPSISPLNS 391

Query: 189 RYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           RYMSPY+P               Q +PLHYSESATSFSP+ASAQSLP C
Sbjct: 392 RYMSPYLPSPSNASPSLVCSSSHQQHPLHYSESATSFSPFASAQSLPEC 440


>ref|XP_006434598.1| hypothetical protein CICLE_v10001161mg [Citrus clementina]
           gi|557536720|gb|ESR47838.1| hypothetical protein
           CICLE_v10001161mg [Citrus clementina]
          Length = 296

 Score =  112 bits (280), Expect = 3e-22
 Identities = 56/109 (51%), Positives = 68/109 (62%)
 Frame = +3

Query: 9   HSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNS 188
           HS++STPY                    +DLR+ SSQRS  +Y++S HS+GYPS+SPLNS
Sbjct: 184 HSVASTPYIPQSLRSYCQSPPISVSQSSLDLRHASSQRSHGSYIMSSHSIGYPSISPLNS 243

Query: 189 RYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           RYMSPY+P               Q +PLHYSESATSFSP+ASAQSLP C
Sbjct: 244 RYMSPYLPSPSNASPSLVCSSSHQQHPLHYSESATSFSPFASAQSLPEC 292


>ref|XP_006434597.1| hypothetical protein CICLE_v10001161mg [Citrus clementina]
           gi|557536719|gb|ESR47837.1| hypothetical protein
           CICLE_v10001161mg [Citrus clementina]
          Length = 370

 Score =  112 bits (280), Expect = 3e-22
 Identities = 56/109 (51%), Positives = 68/109 (62%)
 Frame = +3

Query: 9   HSISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNS 188
           HS++STPY                    +DLR+ SSQRS  +Y++S HS+GYPS+SPLNS
Sbjct: 258 HSVASTPYIPQSLRSYCQSPPISVSQSSLDLRHASSQRSHGSYIMSSHSIGYPSISPLNS 317

Query: 189 RYMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           RYMSPY+P               Q +PLHYSESATSFSP+ASAQSLP C
Sbjct: 318 RYMSPYLPSPSNASPSLVCSSSHQQHPLHYSESATSFSPFASAQSLPEC 366


>ref|XP_011001793.1| PREDICTED: receptor homology region, transmembrane domain- and RING
           domain-containing protein 2-like isoform X2 [Populus
           euphratica] gi|743919955|ref|XP_011004011.1| PREDICTED:
           receptor homology region, transmembrane domain- and RING
           domain-containing protein 2-like isoform X2 [Populus
           euphratica]
          Length = 437

 Score =  109 bits (272), Expect = 2e-21
 Identities = 60/108 (55%), Positives = 67/108 (62%)
 Frame = +3

Query: 12  SISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNSR 191
           S+SSTPY                     DLRNMSSQRSRA++LVSP+SLGYPS+SPLN+R
Sbjct: 331 SLSSTPYAQQSLRSYRHSPSITLSQSSADLRNMSSQRSRASFLVSPNSLGYPSISPLNTR 390

Query: 192 YMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           YMS YIP               QP PLH SESA SFSP+ASAQSLP C
Sbjct: 391 YMSSYIP-SPSNASPSLVSSSHQPRPLHCSESAASFSPFASAQSLPDC 437


>ref|XP_011001792.1| PREDICTED: receptor homology region, transmembrane domain- and RING
           domain-containing protein 2-like isoform X1 [Populus
           euphratica] gi|743919953|ref|XP_011004010.1| PREDICTED:
           receptor homology region, transmembrane domain- and RING
           domain-containing protein 2-like isoform X1 [Populus
           euphratica]
          Length = 441

 Score =  109 bits (272), Expect = 2e-21
 Identities = 60/108 (55%), Positives = 67/108 (62%)
 Frame = +3

Query: 12  SISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNSR 191
           S+SSTPY                     DLRNMSSQRSRA++LVSP+SLGYPS+SPLN+R
Sbjct: 335 SLSSTPYAQQSLRSYRHSPSITLSQSSADLRNMSSQRSRASFLVSPNSLGYPSISPLNTR 394

Query: 192 YMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           YMS YIP               QP PLH SESA SFSP+ASAQSLP C
Sbjct: 395 YMSSYIP-SPSNASPSLVSSSHQPRPLHCSESAASFSPFASAQSLPDC 441


>emb|CBI18269.3| unnamed protein product [Vitis vinifera]
          Length = 424

 Score =  109 bits (272), Expect = 2e-21
 Identities = 54/85 (63%), Positives = 62/85 (72%)
 Frame = +3

Query: 102 RNMSSQRSRAAYLVSPHSLGYPSLSPLNSRYMSPYIPXXXXXXXXXXXXXXRQPNPLHYS 281
           +N SSQRS A+YLVSPHS+GYPSLSPLNSRY+SPYIP              R P+PLHYS
Sbjct: 333 QNASSQRSHASYLVSPHSMGYPSLSPLNSRYLSPYIPSPSNASLSYVGSSSRPPHPLHYS 392

Query: 282 ESATSFSPYASAQSLPGC*RNYSQR 356
           ESATSFSPY SAQSLP    +Y+ +
Sbjct: 393 ESATSFSPYTSAQSLPEFILDYADK 417


>ref|XP_002325986.1| hypothetical protein POPTR_0019s11200g [Populus trichocarpa]
           gi|222862861|gb|EEF00368.1| hypothetical protein
           POPTR_0019s11200g [Populus trichocarpa]
          Length = 437

 Score =  109 bits (272), Expect = 2e-21
 Identities = 60/108 (55%), Positives = 66/108 (61%)
 Frame = +3

Query: 12  SISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNSR 191
           S+SSTPY                     DLRNMSS RSRA++LVSPHSLGYPS+SPLN+R
Sbjct: 331 SLSSTPYAQQSLRSYRHSPSITLSQSSADLRNMSSLRSRASFLVSPHSLGYPSISPLNTR 390

Query: 192 YMSPYIPXXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           YMS YIP              RQP PLH SESA SFSP+ASA SLP C
Sbjct: 391 YMSAYIP-SPSNASPSLVSSSRQPRPLHCSESAASFSPFASAHSLPDC 437


>ref|XP_012075161.1| PREDICTED: receptor homology region, transmembrane domain- and RING
           domain-containing protein 2 [Jatropha curcas]
           gi|643726678|gb|KDP35345.1| hypothetical protein
           JCGZ_10986 [Jatropha curcas]
          Length = 443

 Score =  108 bits (270), Expect = 4e-21
 Identities = 59/109 (54%), Positives = 68/109 (62%), Gaps = 1/109 (0%)
 Frame = +3

Query: 12  SISSTPYNXXXXXXXXXXXXXXXXXXXVDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNSR 191
           S+SSTPY                      LR++SSQRS A++L+SPHSLGYPS+SPLNSR
Sbjct: 335 SLSSTPYIQQSFRSYHQSPSLSISHSSASLRHVSSQRSVASHLMSPHSLGYPSISPLNSR 394

Query: 192 YMSPYIP-XXXXXXXXXXXXXXRQPNPLHYSESATSFSPYASAQSLPGC 335
           YMSPYIP               R P+PLHYSESA SFSP+ASAQSLP C
Sbjct: 395 YMSPYIPSPSNASPSLISSSSHRHPHPLHYSESAASFSPFASAQSLPEC 443


>ref|XP_006353622.1| PREDICTED: E3 ubiquitin-protein ligase RNF13-like [Solanum
           tuberosum]
          Length = 441

 Score =  108 bits (269), Expect = 5e-21
 Identities = 54/81 (66%), Positives = 60/81 (74%)
 Frame = +3

Query: 93  VDLRNMSSQRSRAAYLVSPHSLGYPSLSPLNSRYMSPYIPXXXXXXXXXXXXXXRQPNPL 272
           +DL+N SSQRSRAAYL+S +SLGYP LSPLNSRY S YIP              RQPNPL
Sbjct: 359 LDLQNASSQRSRAAYLISSNSLGYPCLSPLNSRYGSAYIPSPSNPSSSYMGSTSRQPNPL 418

Query: 273 HYSESATSFSPYASAQSLPGC 335
           H+SES TSFSP+ASA SLPGC
Sbjct: 419 HHSESITSFSPFASANSLPGC 439