BLASTX nr result
ID: Coptis25_contig00001480
seq
BLASTX 2.2.25 [Feb-01-2011] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Coptis25_contig00001480 (2375 letters) Database: ./nr 23,641,837 sequences; 8,123,359,852 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|XP_002276254.1| PREDICTED: uncharacterized protein LOC100248... 292 3e-76 ref|XP_002523956.1| RAB6-interacting protein, putative [Ricinus ... 281 4e-73 ref|XP_002329237.1| predicted protein [Populus trichocarpa] gi|2... 264 7e-68 ref|XP_003544935.1| PREDICTED: uncharacterized protein LOC100819... 260 1e-66 ref|XP_002275508.1| PREDICTED: uncharacterized protein LOC100260... 254 6e-65 >ref|XP_002276254.1| PREDICTED: uncharacterized protein LOC100248527 [Vitis vinifera] Length = 617 Score = 292 bits (747), Expect = 3e-76 Identities = 171/402 (42%), Positives = 251/402 (62%), Gaps = 8/402 (1%) Frame = +3 Query: 1011 KIKALEKELVAMRSKLETSEEEAEKLRLLIQKNESSEGDFDSQADPLSSSSFS-ENREIQ 1187 KI E+EL A + K++ SEEE +L+ +QK + QA+ + + +E + Sbjct: 217 KIAGYEEELRAAKEKIQLSEEEIVRLKTELQKYGPLNFTNNFQAELVELPPRDIKMQESE 276 Query: 1188 INLRSNQVD-------GLETRITDQEQRVKALEEELEIRNDQLQLLEEEIGRLNLELEKN 1346 + Q GLE +D ++++L EEL I ++LQ E+EI L EL Sbjct: 277 LEFAKKQASEFEEGAVGLEVDCSDPGLKIQSLVEELRITKERLQGSEKEIATLIDELASR 336 Query: 1347 KTFVANTDNLKVWLXXXXXXXXXXXXXLAMERKRILDLQEQIRRFEIIVLDRDNEIMKVK 1526 + + +++ L L E++ + LQE++ R++ + DR++EI ++K Sbjct: 337 GSS-ESISHMQEQLELTHKDIAMWKAKLDREKREVSKLQERVGRYKTSLSDREHEIRELK 395 Query: 1527 VAISEAEENFTLEKSQLHEKIFFISDSQAHLEGKLKEWELKVRSLEEEIKCIEAEKLKIQ 1706 IS+A+ NF LEKS L KI + D Q+HLE KLKEWEL+ +SLEEEIK ++AEK + + Sbjct: 396 EVISDADHNFELEKSLLMAKISKLLDDQSHLEEKLKEWELRCQSLEEEIKQVDAEKRETK 455 Query: 1707 DSQVARETVIQSEIKQLRADITEKGNHVEVLNKSLDALKLKFDMLVAEKDQLNAKVHTLT 1886 +E + ++EI+QL+AD E G+ + LNKSLDAL LK D L++E+D+L+A+VH L Sbjct: 456 ARLEEQEKLWKTEIEQLKADTAESGDRINDLNKSLDALNLKHDTLMSERDELSARVHALI 515 Query: 1887 EEACSRDDIIHQKDEHLHRLHMEHVDLIAGSEGHRKLVRELKTRVETLEEEVDRQQTVIS 2066 E SRDD Q D++LH+L +E +L+AG+ R+LV EL+++ + LEEEV+RQ+ ++S Sbjct: 516 SELSSRDDQKIQMDKYLHQLRIEQAELVAGAGDARRLVEELRSKAKQLEEEVERQKGLVS 575 Query: 2067 EGAEEKREAIRQLCFSLEHYRNGYHELRQAFLVHKRPTVLAS 2192 E AEEKREAIRQLCFSLEHYRN Y+ LRQAF VHKRP VL S Sbjct: 576 EAAEEKREAIRQLCFSLEHYRNDYNRLRQAFTVHKRPAVLTS 617 Score = 206 bits (523), Expect = 3e-50 Identities = 96/114 (84%), Positives = 106/114 (92%) Frame = +3 Query: 132 MANSSHKMKRLESRKSHSWWWDSHISPKNSKWLAENLEEMDQSVKRMLKLIEEDGDSFAK 311 + S +KR ES+KSHSWWWDSHISPKNSKWLA+NLEEMDQSVKRMLKLIEEDGDSFAK Sbjct: 5 LVKSQKNLKRTESKKSHSWWWDSHISPKNSKWLADNLEEMDQSVKRMLKLIEEDGDSFAK 64 Query: 312 KAEMYYQKRPELVAHVEEFYRMYRSLAERYDNLTGELRKNIPSDLHSQGSGISD 473 KAEMYYQKRPEL++HVE+FYR+YRSLAERYD++TGELRKNI SDL SQGSGISD Sbjct: 65 KAEMYYQKRPELISHVEDFYRIYRSLAERYDHVTGELRKNILSDLQSQGSGISD 118 >ref|XP_002523956.1| RAB6-interacting protein, putative [Ricinus communis] gi|223536803|gb|EEF38443.1| RAB6-interacting protein, putative [Ricinus communis] Length = 628 Score = 281 bits (720), Expect = 4e-73 Identities = 181/515 (35%), Positives = 274/515 (53%), Gaps = 8/515 (1%) Frame = +3 Query: 672 NNFLSSPVNGNGEGLHQRIIELEAEVCEVKEKLRVAEENSEALAAVAGNGNHEDIVGTNT 851 NN+ NG L +++IELE E+ E+K++L++ +E++ G+G++ Sbjct: 184 NNYSVLLGNGGDNALSRKVIELEIELREMKDRLQMQQEDN-------GDGSYR------- 229 Query: 852 WYDEELKVASEKLRLSEEEILRLKAELNLEHGHVLELQEQIAEKEASFRVSDDKIKALEK 1031 + +F +I E+ Sbjct: 230 -----------------------------------------GARNENFEYLLARIAGYEQ 248 Query: 1032 ELVAMRSKLETSEEEAEKLRLLIQKNESSEGDFDSQADPLSSS--------SFSENREIQ 1187 EL ++ SEEE +L + + + +S E Q + +SS S E+ Q Sbjct: 249 ELKIANQSIQHSEEEVARLNIELHRYKSLEAVNSLQKEFISSKDENVKTEDSELESEITQ 308 Query: 1188 INLRSNQVDGLETRITDQEQRVKALEEELEIRNDQLQLLEEEIGRLNLELEKNKTFVANT 1367 + DGLE D + +++AL +EL I ++LQ E+EI L L+LE N+ Sbjct: 309 ASKLKENTDGLEAGTVDSDSKIRALTDELRITKEKLQYAEKEIASLKLQLESNRPS-EKV 367 Query: 1368 DNLKVWLXXXXXXXXXXXXXLAMERKRILDLQEQIRRFEIIVLDRDNEIMKVKVAISEAE 1547 DNL+ L L E++ + LQE+I R + DRD+EI +K+A+S+AE Sbjct: 368 DNLQDQLILAHKDINTWKTRLNAEKREVSKLQERIARLRTSLSDRDHEIRDLKLAVSDAE 427 Query: 1548 ENFTLEKSQLHEKIFFISDSQAHLEGKLKEWELKVRSLEEEIKCIEAEKLKIQDSQVARE 1727 + EK+Q+ +I + + + L+ +L+EWE + R LE++I+ ++ EK + ++ Sbjct: 428 QKIFPEKAQIKAEISKLLEERTSLDEQLREWESRCRCLEDDIRKLQTEKSETEERHY--- 484 Query: 1728 TVIQSEIKQLRADITEKGNHVEVLNKSLDALKLKFDMLVAEKDQLNAKVHTLTEEACSRD 1907 SEI QL+A+ E+ H+E LNKSL+ALKL E+D LNA+V L + SRD Sbjct: 485 ----SEINQLKAETVERDCHIENLNKSLNALKL-------ERDALNAQVVLLKADIISRD 533 Query: 1908 DIIHQKDEHLHRLHMEHVDLIAGSEGHRKLVRELKTRVETLEEEVDRQQTVISEGAEEKR 2087 D I+Q D HL +LHMEHV+LIAG+E RKLV L+++ LE+EV+RQ+ I+EGAEEKR Sbjct: 534 DQINQMDNHLQQLHMEHVELIAGAEEARKLVYTLRSKANDLEKEVERQKIAITEGAEEKR 593 Query: 2088 EAIRQLCFSLEHYRNGYHELRQAFLVHKRPTVLAS 2192 EAIRQLCFSLEHYRNGYH LR+AF+ HKR VL + Sbjct: 594 EAIRQLCFSLEHYRNGYHRLRKAFVEHKRLPVLVT 628 Score = 209 bits (532), Expect = 3e-51 Identities = 99/114 (86%), Positives = 107/114 (93%) Frame = +3 Query: 132 MANSSHKMKRLESRKSHSWWWDSHISPKNSKWLAENLEEMDQSVKRMLKLIEEDGDSFAK 311 M S+ MKRL+SRKSHSWWWDSH+SPKNSKWLAENLEEMD+SV+RMLKLIEEDGDSFAK Sbjct: 5 MVKSNRNMKRLQSRKSHSWWWDSHVSPKNSKWLAENLEEMDRSVRRMLKLIEEDGDSFAK 64 Query: 312 KAEMYYQKRPELVAHVEEFYRMYRSLAERYDNLTGELRKNIPSDLHSQGSGISD 473 KAEMYYQKRPELV+ VEEFYRMYRSLAERYD++TGELRKNIPSDL SQ SGISD Sbjct: 65 KAEMYYQKRPELVSLVEEFYRMYRSLAERYDHVTGELRKNIPSDLQSQSSGISD 118 >ref|XP_002329237.1| predicted protein [Populus trichocarpa] gi|222871018|gb|EEF08149.1| predicted protein [Populus trichocarpa] Length = 545 Score = 264 bits (675), Expect = 7e-68 Identities = 173/456 (37%), Positives = 265/456 (58%) Frame = +3 Query: 825 HEDIVGTNTWYDEELKVASEKLRLSEEEILRLKAELNLEHGHVLELQEQIAEKEASFRVS 1004 H+ I+ T +L EKLR+ EEE + LN E+ ++ Sbjct: 153 HKKIIVMGT----DLSSMEEKLRMHEEE--NRDSMLN-------------GEENRNYEEL 193 Query: 1005 DDKIKALEKELVAMRSKLETSEEEAEKLRLLIQKNESSEGDFDSQADPLSSSSFSENREI 1184 +I E+EL + KL+ SE++ +L++ ++K+ F + L + ++I Sbjct: 194 LSRIIGYEEELRLTKVKLQLSEDDVTRLKIELEKSVF----FRDLSGTLQAQLELALKDI 249 Query: 1185 QINLRSNQVDGLETRITDQEQRVKALEEELEIRNDQLQLLEEEIGRLNLELEKNKTFVAN 1364 Q+ QV+ R+ + +++V EEL+ QL++ EEEI LN +L N Sbjct: 250 QMREDDLQVE--RKRVLELQKKVAEGSEELQ---GQLKVAEEEITMLNAKL--------N 296 Query: 1365 TDNLKVWLXXXXXXXXXXXXXLAMERKRILDLQEQIRRFEIIVLDRDNEIMKVKVAISEA 1544 T E +R+LDLQE+I ++ + D D+EI A+ +A Sbjct: 297 T-----------------------ESRRVLDLQERITCYKSDLSDHDHEIK----ALKDA 329 Query: 1545 EENFTLEKSQLHEKIFFISDSQAHLEGKLKEWELKVRSLEEEIKCIEAEKLKIQDSQVAR 1724 +EN ++EK+ L +I +S+ Q LE KL+EW+L+ + +E++++ EAEK+++++ A+ Sbjct: 330 QENLSVEKAHLQSEILDLSEKQNMLEVKLREWDLQGKFMEDKLRQCEAEKMQMKNLHDAQ 389 Query: 1725 ETVIQSEIKQLRADITEKGNHVEVLNKSLDALKLKFDMLVAEKDQLNAKVHTLTEEACSR 1904 E +Q EI QL+ ++ ++G HVEVLNK D+LK K+DML+AEKD ++AKV+TL + SR Sbjct: 390 EIALQGEISQLKVELIDRGEHVEVLNKKFDSLKSKYDMLMAEKDGMSAKVNTLIADVNSR 449 Query: 1905 DDIIHQKDEHLHRLHMEHVDLIAGSEGHRKLVRELKTRVETLEEEVDRQQTVISEGAEEK 2084 D+ I Q + HL +LH EH LIAGS+ RKLV EL+ +V LE+EVD Q+ +S AEEK Sbjct: 450 DNQIRQMEGHLQQLHTEHEKLIAGSQSSRKLVDELRLKVVELEKEVDGQRVELSAVAEEK 509 Query: 2085 REAIRQLCFSLEHYRNGYHELRQAFLVHKRPTVLAS 2192 R AIRQLCFSLEHYR+GY ELR+AFL HKR +V+AS Sbjct: 510 RAAIRQLCFSLEHYRSGYKELREAFLGHKRHSVMAS 545 Score = 78.6 bits (192), Expect = 7e-12 Identities = 40/70 (57%), Positives = 53/70 (75%) Frame = +3 Query: 249 MDQSVKRMLKLIEEDGDSFAKKAEMYYQKRPELVAHVEEFYRMYRSLAERYDNLTGELRK 428 M++SVK+MLKLIEEDG S AKKAEM Q RP+L++ ++EF M +SLAE Y+ +T EL Sbjct: 1 MERSVKQMLKLIEEDGVSLAKKAEMCRQTRPDLISKIKEFNSMQQSLAECYEYVTTELTN 60 Query: 429 NIPSDLHSQG 458 +IPS+ QG Sbjct: 61 SIPSEFDVQG 70 >ref|XP_003544935.1| PREDICTED: uncharacterized protein LOC100819525 [Glycine max] Length = 623 Score = 260 bits (664), Expect = 1e-66 Identities = 178/511 (34%), Positives = 264/511 (51%), Gaps = 5/511 (0%) Frame = +3 Query: 672 NNFLSSPVNGNGEGLHQRIIELEAEVCEVKEKLRVAEENSEALAAVAGNGNHEDIVGTNT 851 NN+L NG+ G+++RI+ELE E+ EVKEKL Sbjct: 184 NNYLGFSRNGSDLGINRRIMELETELREVKEKL--------------------------- 216 Query: 852 WYDEELKVASEKLRLSEEEILRLKAELNLEHGHVLELQEQIAEKEASFRVSDDKIKALEK 1031 W EE V R S E N E + KI A E+ Sbjct: 217 WMQEEEHVDGSS-RGSRSE--------NTEDVYT-------------------KINAYEQ 248 Query: 1032 ELVAMRSKLETSEEEAEKLRLLIQK-----NESSEGDFDSQADPLSSSSFSENREIQINL 1196 EL+ + KL SEEE KL++ ++K E+ E F+S + + E E + Sbjct: 249 ELMTVNEKLRLSEEEITKLKIELEKYRLFNTENLEAGFESSSMKEHINEGGEALEHKTIE 308 Query: 1197 RSNQVDGLETRITDQEQRVKALEEELEIRNDQLQLLEEEIGRLNLELEKNKTFVANTDNL 1376 +DG++ + DQ ++ L EL I + L+ E +I L E K+ + L Sbjct: 309 LEGSIDGVDKELFDQNGEIETLVRELRITKENLKASEMQITSLKFEANKSSERI---QQL 365 Query: 1377 KVWLXXXXXXXXXXXXXLAMERKRILDLQEQIRRFEIIVLDRDNEIMKVKVAISEAEENF 1556 L E++ L E++ R + DRD+EI +K A+S+ E+ Sbjct: 366 HDQLELARKDISTWKTKFNSEKRESTKLHERLARLRTSLSDRDHEIRDLKTAVSDTEQKI 425 Query: 1557 TLEKSQLHEKIFFISDSQAHLEGKLKEWELKVRSLEEEIKCIEAEKLKIQDSQVARETVI 1736 EK+QL ++ + D + HLE +++EWE + R E+EI+ I++EK++ +++ + Sbjct: 426 FPEKAQLKSEMSKVLDKRTHLEERIREWESRGRCFEDEIRRIQSEKMETEEA-------L 478 Query: 1737 QSEIKQLRADITEKGNHVEVLNKSLDALKLKFDMLVAEKDQLNAKVHTLTEEACSRDDII 1916 + EI+ L+ADI ++ ++++ LN LD LKL EKD L+ +V++L EE SRD I Sbjct: 479 KGEIQLLKADIEQRESNIKDLNTILDTLKL-------EKDNLHVEVYSLKEEVNSRDGRI 531 Query: 1917 HQKDEHLHRLHMEHVDLIAGSEGHRKLVRELKTRVETLEEEVDRQQTVISEGAEEKREAI 2096 + HL++LHMEHV LIAG + +K V ELK++ + LEEEV+RQ+TVI EG EEKREAI Sbjct: 532 EHLNTHLNQLHMEHVQLIAGMDEAQKQVEELKSKAKQLEEEVERQKTVILEGEEEKREAI 591 Query: 2097 RQLCFSLEHYRNGYHELRQAFLVHKRPTVLA 2189 RQLCFSLEHYR+GY+ LRQ + HKR VLA Sbjct: 592 RQLCFSLEHYRDGYNMLRQHVMGHKRVPVLA 622 Score = 204 bits (520), Expect = 7e-50 Identities = 98/112 (87%), Positives = 106/112 (94%) Frame = +3 Query: 138 NSSHKMKRLESRKSHSWWWDSHISPKNSKWLAENLEEMDQSVKRMLKLIEEDGDSFAKKA 317 +S +M+RLESRKSHSWWWDSHISPKNSKWL ENLEEMD+SVKRMLKLIEED DSFAKKA Sbjct: 7 HSCKQMRRLESRKSHSWWWDSHISPKNSKWLFENLEEMDRSVKRMLKLIEEDADSFAKKA 66 Query: 318 EMYYQKRPELVAHVEEFYRMYRSLAERYDNLTGELRKNIPSDLHSQGSGISD 473 EMYYQKRPELVA VEEFYR+YR+LAERYD++TGELRKNIPSDL SQGSGISD Sbjct: 67 EMYYQKRPELVALVEEFYRVYRALAERYDHVTGELRKNIPSDLQSQGSGISD 118 >ref|XP_002275508.1| PREDICTED: uncharacterized protein LOC100260478 [Vitis vinifera] Length = 539 Score = 254 bits (650), Expect = 6e-65 Identities = 166/437 (37%), Positives = 245/437 (56%), Gaps = 26/437 (5%) Frame = +3 Query: 960 LQEQIAEKEASFRVSDDK-------------IKALEKELVAMRSKLETSEEEAEKLRLLI 1100 LQ + + +V++DK + L ++ KLE SEEE +L + Sbjct: 141 LQTMLPSMKEKLQVTEDKDADCIPKVGTHASYEELLGKITEYSQKLEFSEEEIARLNCEL 200 Query: 1101 QKNESSEGDFDSQADPLSSSSFSENREIQINLRSNQV-------DGLETRITDQEQRVKA 1259 +KNES+ G +Q + S+ E +E + L QV LE R+++ + ++ Sbjct: 201 KKNESATGTLQAQLE--SAWREIEMQEANLELEKRQVLELQKQTAELENRVSESDHKICM 258 Query: 1260 LEEELEIRNDQLQLLEEEIGRLNLELEKNKTFVANTDNLKVWLXXXXXXXXXXXXXLAME 1439 LEEELE +L EEE +L EL + V + +E Sbjct: 259 LEEELEETKKRLMGSEEENEKLKHELTNEISVVKHQ----------------------LE 296 Query: 1440 RKRIL------DLQEQIRRFEIIVLDRDNEIMKVKVAISEAEENFTLEKSQLHEKIFFIS 1601 +R L LQ+ I + V D D E+ + A+ A+ENF+LE++QL I +S Sbjct: 297 DQRALAVMLETQLQDSIIKHMAFVSDHDREVESLNAALHNAQENFSLERAQLQSDISSLS 356 Query: 1602 DSQAHLEGKLKEWELKVRSLEEEIKCIEAEKLKIQDSQVARETVIQSEIKQLRADITEKG 1781 LE +L+EW A++++++ A+ETV+ EI+QL+A+++E+G Sbjct: 357 KQVVLLETRLEEWR--------------AKEMEMKGLHEAQETVLLGEIEQLKAELSERG 402 Query: 1782 NHVEVLNKSLDALKLKFDMLVAEKDQLNAKVHTLTEEACSRDDIIHQKDEHLHRLHMEHV 1961 + V+ LNK+LDALK+ +DML+AEKD+L+A+V TL + S D+ I Q ++HL +L +E V Sbjct: 403 DIVQALNKNLDALKVTYDMLMAEKDELSARVDTLIADVNSWDNQIQQLEDHLRQLRIERV 462 Query: 1962 DLIAGSEGHRKLVRELKTRVETLEEEVDRQQTVISEGAEEKREAIRQLCFSLEHYRNGYH 2141 +LIAG+E RKLV EL RV+ LE EV+RQ+ VIS+ AEEKREAIRQLCFSLEHYR+GY Sbjct: 463 ELIAGTESARKLVDELSWRVKELEREVERQRVVISDRAEEKREAIRQLCFSLEHYRSGYQ 522 Query: 2142 ELRQAFLVHKRPTVLAS 2192 ELRQAF+ HKR +LAS Sbjct: 523 ELRQAFIGHKRLPILAS 539 Score = 103 bits (257), Expect = 2e-19 Identities = 52/69 (75%), Positives = 61/69 (88%) Frame = +3 Query: 249 MDQSVKRMLKLIEEDGDSFAKKAEMYYQKRPELVAHVEEFYRMYRSLAERYDNLTGELRK 428 M+QSVK+MLKLIEE GDSF +KAEMY +KRPELVAHVEEFYRMY++LAER D+LTGEL K Sbjct: 1 MEQSVKQMLKLIEEGGDSFEEKAEMYNRKRPELVAHVEEFYRMYQALAERCDHLTGELFK 60 Query: 429 NIPSDLHSQ 455 + PS L +Q Sbjct: 61 SNPSMLQAQ 69 Score = 81.3 bits (199), Expect = 1e-12 Identities = 99/406 (24%), Positives = 174/406 (42%), Gaps = 40/406 (9%) Frame = +3 Query: 672 NNFLSSPVNGNGEGLHQRIIELEAEVCEVKEKLRVAEE-NSEALAAVAGNGNHEDIVGTN 848 N +L +P NG+G+GL + + KEKL+V E+ +++ + V + ++E+++G Sbjct: 127 NRYLGTPSNGDGKGLQTMLPSM-------KEKLQVTEDKDADCIPKVGTHASYEELLGKI 179 Query: 849 TWYDEELKVASEKLRLSEEEILRLKAELN----------------------------LEH 944 T Y S+KL SEEEI RL EL LE Sbjct: 180 TEY-------SQKLEFSEEEIARLNCELKKNESATGTLQAQLESAWREIEMQEANLELEK 232 Query: 945 GHVLELQEQIAEKEASFRVSDDKIKALEKELVAMRSKLETSEEEAEKLRLLIQKNESSEG 1124 VLELQ+Q AE E SD KI LE+EL + +L SEEE EKL+ + NE S Sbjct: 233 RQVLELQKQTAELENRVSESDHKICMLEEELEETKKRLMGSEEENEKLKHEL-TNEIS-- 289 Query: 1125 DFDSQADPLSSSSFSENREIQINLRSNQVDGLETR---ITDQEQRVKALEEELEIRNDQL 1295 + + R + + L + D + ++D ++ V++L L + Sbjct: 290 --------VVKHQLEDQRALAVMLETQLQDSIIKHMAFVSDHDREVESLNAALHNAQENF 341 Query: 1296 QL----LEEEIGRLNLELEKNKTFVANTDNLKVWLXXXXXXXXXXXXXLAMERKRILDLQ 1463 L L+ +I L +K V L+ W ME K + + Q Sbjct: 342 SLERAQLQSDISSL------SKQVVLLETRLEEW------------RAKEMEMKGLHEAQ 383 Query: 1464 EQIRRFEIIVLDRD-NEIMKVKVAISEAEENFTLEKSQLHEKIFFISDSQAHLEGKLKEW 1640 E + EI L + +E + A+++ + + L + +S L + W Sbjct: 384 ETVLLGEIEQLKAELSERGDIVQALNKNLDALKVTYDMLMAEKDELSARVDTLIADVNSW 443 Query: 1641 ELKVRSLEEEIKCIEAEKLK-IQDSQVARETV--IQSEIKQLRADI 1769 + +++ LE+ ++ + E+++ I ++ AR+ V + +K+L ++ Sbjct: 444 DNQIQQLEDHLRQLRIERVELIAGTESARKLVDELSWRVKELEREV 489