BLASTX nr result
ID: Coptis25_contig00001367
seq
BLASTX 2.2.25 [Feb-01-2011] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Coptis25_contig00001367 (2512 letters) Database: ./nr 23,641,837 sequences; 8,123,359,852 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|XP_002281776.1| PREDICTED: two-component response regulator-... 559 e-156 ref|XP_002311123.1| pseudo response regulator [Populus trichocar... 534 e-149 ref|XP_002316333.1| pseudo response regulator [Populus trichocar... 523 e-146 ref|XP_002311124.1| predicted protein [Populus trichocarpa] gi|2... 521 e-145 ref|XP_002531836.1| sensory transduction histidine kinase, putat... 516 e-144 >ref|XP_002281776.1| PREDICTED: two-component response regulator-like PRR73-like [Vitis vinifera] Length = 785 Score = 559 bits (1441), Expect = e-156 Identities = 329/643 (51%), Positives = 401/643 (62%), Gaps = 34/643 (5%) Frame = -2 Query: 2154 MGSVPVNTRGGGN-------RAEW-------YGVVREGQGQGLSEEDESKINEVARGVNV 2017 MG V N GGG + W G+V EGQG G SEEDE NE+ N Sbjct: 1 MGFVQANNDGGGEGGLVNRENSTWDEGKEVRNGMVGEGQGLGSSEEDEPGSNEIIEDANK 60 Query: 2016 A---LXXXXXXXXXXXXXPSASLVHWERFLPRRSLKVLLVENDDSTRHVVSALLRNCSYQ 1846 P S ++W+ FLP RSLKVLLVENDDSTRHVV+ALLRNCSY+ Sbjct: 61 GSEEAIQVHDGLQNSQQQPQGSAINWDSFLPIRSLKVLLVENDDSTRHVVTALLRNCSYE 120 Query: 1845 VVAVSNGLHAWKILQELTNDIDLILTEVVMPCLSGIGLLCKIMNHKTCKNVPVIXXXXXX 1666 V AV+NGL AWKIL++LTN ID++LTEVVMP +SGIGLLCKIM+HKT KN+PVI Sbjct: 121 VTAVANGLQAWKILEDLTNHIDIVLTEVVMPFISGIGLLCKIMSHKTFKNIPVI------ 174 Query: 1665 XXXXXXXXXXXXXXXXXXXMSSHDSMGIVFKCLSKGAVDFLVKPIRKNELKNLWQHVWRR 1486 MSSHDSMGIVFKCLSKGAVDFLVKPIRKNELKNLWQHVWRR Sbjct: 175 ------------------MMSSHDSMGIVFKCLSKGAVDFLVKPIRKNELKNLWQHVWRR 216 Query: 1485 CHXXXXXXXXXXXGIQARKSVKSKSMDESDNSTGSNDEDDDGSVGLNVRDGSDNGSGTQS 1306 CH G Q +KSVKSKS DES+N+TGS+DE D+GS G ++RDGSDNGSGTQS Sbjct: 217 CH--SSSGSGSESGTQTKKSVKSKSNDESENNTGSSDERDNGSTGPSIRDGSDNGSGTQS 274 Query: 1305 SWTRRTVEGYSPQLLSPWDQLA---ESTCTQVIHPKSESFSREWVPIGEKKECSHHDEKL 1135 SWT+R E SPQ LSP DQLA +STC QVIH K + S +WV + E KEC DE+ Sbjct: 275 SWTKRAAEVDSPQPLSPLDQLADAPDSTCPQVIHTKPGTLSNQWVHVIETKECQGKDEQ- 333 Query: 1134 LENVAMGKDLEIGVSRNAELQHEYQSENICTNLVGSNKNKMPELGPQAEIEPLDKGPVES 955 +NVAMG+DLE+GV+ N +Q EYQ E T +NK+PE ++ +P DK +E Sbjct: 334 PDNVAMGRDLELGVATNPAVQLEYQHEKFSTYPTCKRQNKLPE----SDSKPFDKEHLEH 389 Query: 954 DGVTARGKLRAQAAEITCLDTCFLPRVETRFRETPASHSKVPEIIDKPTSDANELPSVER 775 + +A C P+VE+R E P S V +I DK + + ELP ++ Sbjct: 390 NSTSA---------------NCTDPQVESRTFENPNGLSDVSQIKDKGSCETTELPPLDL 434 Query: 774 SLKRLRGFGDDGTTAHDDRKILRHSDLSAFSRYNTAYNANQAPTGIVGSCSPLNNNSELV 595 SLKRLRG GD G HDDR ILRHSDLSAFS+YNTA +ANQAPTG VGSCSPL+N+S + Sbjct: 435 SLKRLRGAGDVGACVHDDRSILRHSDLSAFSKYNTASSANQAPTGNVGSCSPLDNSSVAM 494 Query: 594 KTDSMY-----------SQHSNENSNNNDMGSTNKNVFSDPVAFPEKSASTSKERSLYPS 448 KT++M+ +Q SN +SNN DM ST K A+ EKS STS + + S Sbjct: 495 KTETMHNFPSHVDGIPPNQQSNGSSNNIDMVSTTKYAIPKSEAYNEKSESTSAFKCFHSS 554 Query: 447 AFEPLQNTCVCPPLQVTPQKTN---ANTTVAQPRGAHQQVQLQ 328 AF+P+ + + PP +V+ K + + AQ G+HQQVQ+Q Sbjct: 555 AFQPVTSGRMFPPQKVSSGKADDVVVDAVQAQVIGSHQQVQVQ 597 Score = 77.8 bits (190), Expect = 1e-11 Identities = 36/50 (72%), Positives = 40/50 (80%) Frame = -3 Query: 155 SMPGNALQCGSSNMVGGPIEDNTGNYSLNGSASGSRHGSNGQNGSSKDLN 6 +M A QCGSSN++GGP E N GNYS+NGSASGS HGSNGQNGSS LN Sbjct: 628 NMAAAAPQCGSSNVIGGPTEGNAGNYSVNGSASGSNHGSNGQNGSSTALN 677 >ref|XP_002311123.1| pseudo response regulator [Populus trichocarpa] gi|222850943|gb|EEE88490.1| pseudo response regulator [Populus trichocarpa] Length = 766 Score = 534 bits (1375), Expect = e-149 Identities = 306/614 (49%), Positives = 380/614 (61%), Gaps = 28/614 (4%) Frame = -2 Query: 2085 GQGQGLSEEDESKINEVARGVN-------VALXXXXXXXXXXXXXPSASLVHWERFLPRR 1927 G+GQ LSEEDES+INE + +N LV WERFLP R Sbjct: 31 GEGQELSEEDESQINEDGKYMNDKGMELLQVQNDAQAVIQSQQQQSQGPLVIWERFLPLR 90 Query: 1926 SLKVLLVENDDSTRHVVSALLRNCSYQVVAVSNGLHAWKILQELTNDIDLILTEVVMPCL 1747 SLKVLLVENDDSTRHVVSALLRNC Y+V AVSNGL AWK+LQ+LTN IDL+LTEV MPCL Sbjct: 91 SLKVLLVENDDSTRHVVSALLRNCGYEVTAVSNGLQAWKVLQDLTNHIDLVLTEVAMPCL 150 Query: 1746 SGIGLLCKIMNHKTCKNVPVIXXXXXXXXXXXXXXXXXXXXXXXXXMSSHDSMGIVFKCL 1567 SGIGLL KIM+HKTC+N+PVI MSSHDSM +VFKCL Sbjct: 151 SGIGLLSKIMSHKTCRNIPVI------------------------MMSSHDSMNVVFKCL 186 Query: 1566 SKGAVDFLVKPIRKNELKNLWQHVWRRCHXXXXXXXXXXXGIQARKSVKSKSMDESDNST 1387 SKGAVDFLVKPIRKNELK LWQHVWR+CH ++ +KS KS DESDN T Sbjct: 187 SKGAVDFLVKPIRKNELKILWQHVWRKCH--SASGSGSESAVRTQKSTKSNGADESDNDT 244 Query: 1386 GSNDEDDDGSVGLNVRDGSDNGSGTQSSWTRRTVEGYSPQLLSPWDQ-----LAESTCTQ 1222 GSND+D GSVGLN RDGSDNGSGTQSSWT+R VE SP+ +SPWDQ +STC Q Sbjct: 245 GSNDDDGIGSVGLNARDGSDNGSGTQSSWTKRAVEVESPKPMSPWDQDHLSDPPDSTCAQ 304 Query: 1221 VIHPKSESFSREWVPIGEKKECSHHDEKLLENVAMGKDLEIGVSRNAELQHEYQSENICT 1042 VIH + E+ WVP+ K+C D++ L+N+ MGKDLEIGV R LQ + + + T Sbjct: 305 VIHSRPEACDNSWVPLATMKKCGEQDDE-LDNIVMGKDLEIGVPRIPNLQLKDPIKRVPT 363 Query: 1041 NLVGSNKNKMPELGPQAEIEPLDKGPVESDGVTARGKLRAQAAEIT--CLDTCFLPRVET 868 N+ ++ K PE+ + + L+K E + +LR Q ++ + PR+++ Sbjct: 364 NIADNDGEKFPEIKSKHDGGHLEKRQQELNSEKCNTELRNQGNDLKGGGITNSANPRMDS 423 Query: 867 RFRETPASHSKVPEIIDKPTSDANELPSVERSLKRLRGFGDDGTTAHDDRKILRHSDLSA 688 + P S + ++ T + E+PS E SLKRLR GD G ++H DR +LRHSDLSA Sbjct: 424 LVLDVPNGLSSNRK--NEVTYETKEVPSFELSLKRLRDIGDAGASSH-DRNVLRHSDLSA 480 Query: 687 FSRYNTAYNANQAPTGIVGSCSPLNNNSELVKTDSMY-----------SQHSNENSNNND 541 FSRYN+A A+QAPTG VGSCSPL+N+SE KT+SM +Q SN +S+NND Sbjct: 481 FSRYNSASTADQAPTGNVGSCSPLDNSSEAAKTESMQNLQSNSNSTPPNQRSNGSSHNND 540 Query: 540 MGSTNKNVFSDPVAFPEKSASTSKERSLYPSAFEPLQNTCVCPPLQVTPQKTN---ANTT 370 MGSTN F+ P +K + YPSAF+P+QN P V K + ANTT Sbjct: 541 MGSTNNITFAKPSVISDKPTLKPTVKCHYPSAFQPVQNDHTALPQPVIQGKGDAPIANTT 600 Query: 369 VAQPRGAHQQVQLQ 328 + + RG +QQ Q+Q Sbjct: 601 LVKSRGVNQQGQVQ 614 >ref|XP_002316333.1| pseudo response regulator [Populus trichocarpa] gi|222865373|gb|EEF02504.1| pseudo response regulator [Populus trichocarpa] Length = 763 Score = 523 bits (1348), Expect = e-146 Identities = 309/614 (50%), Positives = 380/614 (61%), Gaps = 28/614 (4%) Frame = -2 Query: 2085 GQGQGLSEEDESKINEVARGVN-------VALXXXXXXXXXXXXXPSASLVHWERFLPRR 1927 G+ Q LSEE ES+INE + VN L LVHWERFLPRR Sbjct: 28 GEDQELSEEGESQINEDEKDVNDKGMESLQVLTDAQVVIQSQHQQSQGPLVHWERFLPRR 87 Query: 1926 SLKVLLVENDDSTRHVVSALLRNCSYQVVAVSNGLHAWKILQELTNDIDLILTEVVMPCL 1747 SLKVLLVENDDSTRHVVSALLRNC Y+ AV+NGL AWK+LQ+LTN IDL+LTEV MPCL Sbjct: 88 SLKVLLVENDDSTRHVVSALLRNCGYEATAVANGLQAWKLLQDLTNHIDLVLTEVAMPCL 147 Query: 1746 SGIGLLCKIMNHKTCKNVPVIXXXXXXXXXXXXXXXXXXXXXXXXXMSSHDSMGIVFKCL 1567 SGIGLL IM+HKTC+N+PVI MSSHDSM +VF+CL Sbjct: 148 SGIGLLSNIMSHKTCRNIPVI------------------------MMSSHDSMNVVFRCL 183 Query: 1566 SKGAVDFLVKPIRKNELKNLWQHVWRRCHXXXXXXXXXXXGIQARKSVKSKSMDESDNST 1387 SKGAVDFLVKPIRKNELK LWQHVWRRCH IQ KS+KSK DESDN T Sbjct: 184 SKGAVDFLVKPIRKNELKILWQHVWRRCHSASGSGSESAVRIQ--KSLKSKGADESDNDT 241 Query: 1386 GSNDEDDDGSVGLNVRDGSDNGSGTQSSWTRRTVEGYSPQLLSPWDQLA---ESTCTQVI 1216 SND+DD GS+GLN RDGSDNGSGTQSSWT+R VE SP+ + PWDQLA +ST QVI Sbjct: 242 DSNDDDDIGSIGLNARDGSDNGSGTQSSWTKRAVEVDSPKPMLPWDQLADPPDSTFAQVI 301 Query: 1215 HPKSESFSREWVPIGEKKECSHHDEKLLENVAMGKDLEIGVSRNAELQHEYQSENICTNL 1036 H +SE+ WVP+ K+ D++ L+N MGKDLEIGV R LQH+ S+ + TN+ Sbjct: 302 HSRSEACD-NWVPLATTKKFGKQDDE-LDNFVMGKDLEIGVPRIPNLQHKDLSKEVLTNI 359 Query: 1035 VGSNKNKMPELGPQAEIEPLDKGPVESDGVTARGKLRAQAAEITCLDTCFL-PRVETRFR 859 G+N K E+ + + L+KG +E + +LR Q ++ + T P++E+ Sbjct: 360 AGNNGEKFREIKSEQDSGHLEKGQLELNSEKHNTELRNQGNDLKGVSTNITNPQIESEVV 419 Query: 858 E--TPASHSKVPEIIDKPTSDANELPSVERSLKRLRGFGDDGTTAHDDRKILRHSDLSAF 685 + S +K E+I + E+PS+E LKRLR GD +A +DR +LRHSDLSAF Sbjct: 420 DISNSLSSNKKNEVI----YETKEMPSLELVLKRLRDTGDAWASA-NDRNVLRHSDLSAF 474 Query: 684 SRYNTAYNANQAPTGIVGSCSPLNNNSELVKTDSMYSQHSNEN-----------SNNNDM 538 SRYN+A A QAPTG VGSCS L+ SE KT+SM + SN N SNNND+ Sbjct: 475 SRYNSASTAYQAPTGNVGSCSLLDKCSEAAKTESMQNLQSNSNSTPRNLCSNGSSNNNDV 534 Query: 537 GSTNKNVFSDPVAFPEKSASTSKERSLYP-SAFEPLQNTCVC---PPLQVTPQKTNANTT 370 G+T N F+ P+ +K S + L+P SAF+P+QN P +Q ANT Sbjct: 535 GTTTNNAFAKPLVIRDKPTPKSTVKCLHPSSAFQPVQNDQTLHAQPVIQGKGDAPIANTI 594 Query: 369 VAQPRGAHQQVQLQ 328 +AQ RG +QQ Q+Q Sbjct: 595 LAQSRGMNQQGQVQ 608 >ref|XP_002311124.1| predicted protein [Populus trichocarpa] gi|222850944|gb|EEE88491.1| predicted protein [Populus trichocarpa] Length = 711 Score = 521 bits (1343), Expect = e-145 Identities = 292/565 (51%), Positives = 362/565 (64%), Gaps = 21/565 (3%) Frame = -2 Query: 1959 LVHWERFLPRRSLKVLLVENDDSTRHVVSALLRNCSYQVVAVSNGLHAWKILQELTNDID 1780 LV WERFLP RSLKVLLVENDDSTRHVVSALLRNC Y+V AVSNGL AWK+LQ+LTN ID Sbjct: 25 LVIWERFLPLRSLKVLLVENDDSTRHVVSALLRNCGYEVTAVSNGLQAWKVLQDLTNHID 84 Query: 1779 LILTEVVMPCLSGIGLLCKIMNHKTCKNVPVIXXXXXXXXXXXXXXXXXXXXXXXXXMSS 1600 L+LTEV MPCLSGIGLL KIM+HKTC+N+PVI MSS Sbjct: 85 LVLTEVAMPCLSGIGLLSKIMSHKTCRNIPVI------------------------MMSS 120 Query: 1599 HDSMGIVFKCLSKGAVDFLVKPIRKNELKNLWQHVWRRCHXXXXXXXXXXXGIQARKSVK 1420 HDSM +VFKCLSKGAVDFLVKPIRKNELK LWQHVWR+CH ++ +KS K Sbjct: 121 HDSMNVVFKCLSKGAVDFLVKPIRKNELKILWQHVWRKCH--SASGSGSESAVRTQKSTK 178 Query: 1419 SKSMDESDNSTGSNDEDDDGSVGLNVRDGSDNGSGTQSSWTRRTVEGYSPQLLSPWDQ-- 1246 S DESDN TGSND+D GSVGLN RDGSDNGSGTQSSWT+R VE SP+ +SPWDQ Sbjct: 179 SNGADESDNDTGSNDDDGIGSVGLNARDGSDNGSGTQSSWTKRAVEVESPKPMSPWDQDH 238 Query: 1245 ---LAESTCTQVIHPKSESFSREWVPIGEKKECSHHDEKLLENVAMGKDLEIGVSRNAEL 1075 +STC QVIH + E+ WVP+ K+C D++ L+N+ MGKDLEIGV R L Sbjct: 239 LSDPPDSTCAQVIHSRPEACDNSWVPLATMKKCGEQDDE-LDNIVMGKDLEIGVPRIPNL 297 Query: 1074 QHEYQSENICTNLVGSNKNKMPELGPQAEIEPLDKGPVESDGVTARGKLRAQAAEIT--C 901 Q + + + TN+ ++ K PE+ + + L+K E + +LR Q ++ Sbjct: 298 QLKDPIKRVPTNIADNDGEKFPEIKSKHDGGHLEKRQQELNSEKCNTELRNQGNDLKGGG 357 Query: 900 LDTCFLPRVETRFRETPASHSKVPEIIDKPTSDANELPSVERSLKRLRGFGDDGTTAHDD 721 + PR+++ + P S + ++ T + E+PS E SLKRLR GD G ++H D Sbjct: 358 ITNSANPRMDSLVLDVPNGLSSNRK--NEVTYETKEVPSFELSLKRLRDIGDAGASSH-D 414 Query: 720 RKILRHSDLSAFSRYNTAYNANQAPTGIVGSCSPLNNNSELVKTDSMY-----------S 574 R +LRHSDLSAFSRYN+A A+QAPTG VGSCSPL+N+SE KT+SM + Sbjct: 415 RNVLRHSDLSAFSRYNSASTADQAPTGNVGSCSPLDNSSEAAKTESMQNLQSNSNSTPPN 474 Query: 573 QHSNENSNNNDMGSTNKNVFSDPVAFPEKSASTSKERSLYPSAFEPLQNTCVCPPLQVTP 394 Q SN +S+NNDMGSTN F+ P +K + YPSAF+P+QN P V Sbjct: 475 QRSNGSSHNNDMGSTNNITFAKPSVISDKPTLKPTVKCHYPSAFQPVQNDHTALPQPVIQ 534 Query: 393 QKTN---ANTTVAQPRGAHQQVQLQ 328 K + ANTT+ + RG +QQ Q+Q Sbjct: 535 GKGDAPIANTTLVKSRGVNQQGQVQ 559 >ref|XP_002531836.1| sensory transduction histidine kinase, putative [Ricinus communis] gi|223528532|gb|EEF30556.1| sensory transduction histidine kinase, putative [Ricinus communis] Length = 807 Score = 516 bits (1330), Expect = e-144 Identities = 303/613 (49%), Positives = 385/613 (62%), Gaps = 22/613 (3%) Frame = -2 Query: 2100 GVVREGQGQGLSEEDESKINEVARGVNVA----LXXXXXXXXXXXXXPSASLVHWERFLP 1933 GV+ EG+G G S ED++++++V VN + S++ WERFLP Sbjct: 11 GVMGEGRGLGSSGEDDTRVDDVPVDVNNGPGREVQVHDGFQISQQQQAQNSVIRWERFLP 70 Query: 1932 RRSLKVLLVENDDSTRHVVSALLRNCSYQVVAVSNGLHAWKILQELTNDIDLILTEVVMP 1753 RSLKVLLVENDDSTRHVVSALLRNCSY+V AV+NG AWKIL+++ N DL+LTEVVMP Sbjct: 71 VRSLKVLLVENDDSTRHVVSALLRNCSYEVNAVANGFQAWKILEDMNNHTDLVLTEVVMP 130 Query: 1752 CLSGIGLLCKIMNHKTCKNVPVIXXXXXXXXXXXXXXXXXXXXXXXXXMSSHDSMGIVFK 1573 LSGIGLLCKI NHKT +N+PVI MSSHDSMGIVFK Sbjct: 131 ILSGIGLLCKIRNHKTLRNIPVI------------------------MMSSHDSMGIVFK 166 Query: 1572 CLSKGAVDFLVKPIRKNELKNLWQHVWRRCHXXXXXXXXXXXGIQARKSVKSKSMDESDN 1393 CLSKGAVDFLVKPIRKNELKNLWQHVWRRCH G Q +KS K+KS +ES+N Sbjct: 167 CLSKGAVDFLVKPIRKNELKNLWQHVWRRCH--SSSGSGSESGTQTKKSAKTKSNEESEN 224 Query: 1392 STGSNDE-DDDGSVGLNVRDGSDNGSGTQSSWTRRTVEGYSPQLLSPWDQLA---ESTCT 1225 ++ S+DE D GS G + RDGSDNGSGTQSSWT+R + SP+ +S Q+A +STC Sbjct: 225 NSDSSDELGDYGSNGPSNRDGSDNGSGTQSSWTKRAADIDSPRPMSSAYQMADAPDSTCA 284 Query: 1224 QVIHPKSESFSREWVPIGEKKECSHHDEKLLENVAMGKDLEIGVSRNAELQHEYQSENIC 1045 QVIH K E+F WV + + K D+K ++ AMGKDLEIGVS N + +H+ Q EN+ Sbjct: 285 QVIHTKPETFGNIWVHVTDTKGLQERDDK-HDDFAMGKDLEIGVSSNLDTRHDCQLENLS 343 Query: 1044 TNLVGSNKNKMPELGPQAEIEPLDKGPVESDGVTARGKLRAQAAEITCLDT-CFLPRVET 868 + K+ E+ + +PL+ G +E DG KLR Q ++ + PR+E Sbjct: 344 PRPTSKRQQKISEV----DSKPLENGMLEHDGENLFTKLRDQTPQLASTNADSANPRIEI 399 Query: 867 RFRETPASHSKVPEIIDKPTSDANELPSVERSLKRLRGFGDDGTTAHDDRKILRHSDLSA 688 + + ++ + ++ DK D+ ELPS E SLKRLRG GDDG A DDR +LRHSDLSA Sbjct: 400 K-KVGTSNRPDISQLKDKACCDSGELPSFELSLKRLRGVGDDGNAADDDRNVLRHSDLSA 458 Query: 687 FSRYNTAYNANQAPTGIVGSCSPLNNNSELVKTDSMY-----------SQHSNENSNNND 541 FS+YN +ANQ PT GSCSPL+N+S +KT++ + +Q SN +SNNND Sbjct: 459 FSKYNNGSSANQGPTENGGSCSPLDNSSVAMKTETTHNIPFHLSGTVLNQQSNGSSNNND 518 Query: 540 MGSTNKNVFSDPVAFPEKSASTSKERSLYPSAFEPLQNTCVCPPLQVTPQKT--NANTTV 367 M ST K V P AF +KS STS +S + SAF+P+QN C ++ P K NT Sbjct: 519 MASTAKKVTPKPEAFNDKSESTSTFKSFHSSAFQPVQNGHSC-SWKIKPGKVEDTGNTFH 577 Query: 366 AQPRGAHQQVQLQ 328 AQ RG +QQVQ+Q Sbjct: 578 AQVRGINQQVQVQ 590 Score = 74.7 bits (182), Expect = 1e-10 Identities = 34/50 (68%), Positives = 40/50 (80%) Frame = -3 Query: 155 SMPGNALQCGSSNMVGGPIEDNTGNYSLNGSASGSRHGSNGQNGSSKDLN 6 +M A QCGSSN++GGP E N GNYS+NGSASGS HGSNGQNGS+ L+ Sbjct: 621 NMAAVAPQCGSSNVIGGPTEGNAGNYSMNGSASGSNHGSNGQNGSNTALH 670