BLASTX nr result
ID: Coptis24_contig00006187
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Coptis24_contig00006187
(2176 letters)
Database: ./nr
23,641,837 sequences; 8,123,359,852 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
emb|CBI23362.3| unnamed protein product [Vitis vinifera] 716 0.0
ref|XP_002272174.1| PREDICTED: protein TRANSPARENT TESTA 12-like... 716 0.0
ref|XP_002527924.1| multidrug resistance pump, putative [Ricinus... 705 0.0
ref|XP_003551225.1| PREDICTED: protein TRANSPARENT TESTA 12-like... 683 0.0
ref|XP_003628949.1| Protein TRANSPARENT TESTA [Medicago truncatu... 679 0.0
>emb|CBI23362.3| unnamed protein product [Vitis vinifera]
Length = 1152
Score = 716 bits (1847), Expect = 0.0
Identities = 356/522 (68%), Positives = 416/522 (79%)
Frame = +1
Query: 13 HICESPKPINMEGANQVPLLLHRGDHEDISRQPLKHNGSSFDASLIADGDIEPVKNVNDF 192
H ES +N+ + PLL R D E +R ++F+A + DI P+ V DF
Sbjct: 636 HFSES---LNIMENGKQPLLSARQDDETPNRTAANSLLATFNAD---ESDIGPINGVRDF 689
Query: 193 FREFAVESKKLWFLAGPAIFTSVCQYTLGAVTQAFAGQVGTLELAAVSIENSVIAGFSLG 372
++EF VESKKLW+LAGPAIFTS+CQY+LGA+TQ FAG VGTLELAAVS+ENSVIAGFS G
Sbjct: 690 YKEFIVESKKLWYLAGPAIFTSLCQYSLGAITQVFAGHVGTLELAAVSVENSVIAGFSFG 749
Query: 373 VMMGMGSALETLCGQAFGAGQLDMLGIYMQRSWVILDVTALLLVFLYIFAAQILKLIGQE 552
VM+GMGSALETLCGQAFGAGQLDMLG+YMQRSWVIL TA+LL FLYIF+A++LKLIGQ
Sbjct: 750 VMLGMGSALETLCGQAFGAGQLDMLGVYMQRSWVILTSTAVLLSFLYIFSARLLKLIGQT 809
Query: 553 ENIAETAGKLAIWMIPQLFAYAVNFPQAKFLQAQSKMLVMAIIAFAALVFHTFFSWLFML 732
E I++ AG A+WM+PQLFAYAVNFP AKFLQAQSK++VMA+IA LV HT FSWL ML
Sbjct: 810 EAISKEAGMFAVWMLPQLFAYAVNFPLAKFLQAQSKIMVMAVIAAVVLVLHTVFSWLLML 869
Query: 733 KLGWGLAGAAVVLNASWWFIDIAQFLYIISGTCGRAWTGFSMKAFENLWGFVRLSIASAV 912
KL WGL GAAVVLNASW ID+AQ LYI SGTCGRAWTGFS KAF++LWGFVRLS+ASAV
Sbjct: 870 KLQWGLVGAAVVLNASWVLIDVAQLLYIFSGTCGRAWTGFSWKAFQSLWGFVRLSLASAV 929
Query: 913 MLCLETWYFMALILFAGYLKNPEVSVDGLSICTNILGWTIMVSIGFNASTSVRVANELGA 1092
MLCLE WYFMALILFAGYLKN E+SVD LSIC NILGWT+MV++G NA+ SVRV+NELGA
Sbjct: 930 MLCLEVWYFMALILFAGYLKNAEISVDALSICMNILGWTVMVALGCNAAISVRVSNELGA 989
Query: 1093 NHPRTAKFSIAVVVITSFXXXXXXXXXXXXARKQYPYAFTSNADVRNLVYQLTPLLATSI 1272
HPRTAKF++ VVVITSF RKQYP F+ + +V LV +LTPLLA I
Sbjct: 990 THPRTAKFAVVVVVITSFLIGLVLSAILIIFRKQYPALFSDSEEVEELVDELTPLLAFCI 1049
Query: 1273 LLNMVQPVLSGVAIGAGWQALVAYVNIACYYLFGIPFGLIMGYALDFGVKGIWCGMITGT 1452
++N VQPVLSGVAIGAGWQA VA+VNIACYYLFG+P GL++GY + GVKGIWCGM++GT
Sbjct: 1050 VINNVQPVLSGVAIGAGWQAFVAWVNIACYYLFGVPLGLVLGYKVGLGVKGIWCGMLSGT 1109
Query: 1453 VVQTCILFFITYRTKWDKEASAAGARIQQWRGKAEDSVNDIE 1578
VVQTC+LF + YRT W+KEAS AG RI++W G ND+E
Sbjct: 1110 VVQTCVLFGMVYRTNWNKEASIAGDRIKKWGGNEAGRENDVE 1151
Score = 662 bits (1707), Expect = 0.0
Identities = 320/499 (64%), Positives = 391/499 (78%), Gaps = 1/499 (0%)
Frame = +1
Query: 55 NQVPLLLHRGDHEDISR-QPLKHNGSSFDASLIADGDIEPVKNVNDFFREFAVESKKLWF 231
++ PLL D E +P K SF A+ D D++P+ V DFFREF VESKKLW
Sbjct: 33 DEQPLLSTTHDQEQTQNPRPAKTGFFSFLAANY-DDDMDPINGVGDFFREFRVESKKLWH 91
Query: 232 LAGPAIFTSVCQYTLGAVTQAFAGQVGTLELAAVSIENSVIAGFSLGVMMGMGSALETLC 411
+AGPAIFT +C+Y+LGA+TQ F G +G L+LAA ++ENSVI+ FSLG M+GMGSALETLC
Sbjct: 92 IAGPAIFTYLCRYSLGAITQVFVGHIGALQLAAFAVENSVISMFSLGTMLGMGSALETLC 151
Query: 412 GQAFGAGQLDMLGIYMQRSWVILDVTALLLVFLYIFAAQILKLIGQEENIAETAGKLAIW 591
GQAFGAGQLDMLG+YMQRSW+IL TAL L +YIFA QILKLIG+ E I++ AG A+W
Sbjct: 152 GQAFGAGQLDMLGVYMQRSWIILVTTALPLSLIYIFAEQILKLIGETEEISKAAGVFALW 211
Query: 592 MIPQLFAYAVNFPQAKFLQAQSKMLVMAIIAFAALVFHTFFSWLFMLKLGWGLAGAAVVL 771
M+PQLF+YA++FP +KFLQ+Q KMLV+++ A LV H FFSWL ++KLGWGL GAAVVL
Sbjct: 212 MLPQLFSYALSFPISKFLQSQRKMLVLSLTAGVTLVLHAFFSWLLIMKLGWGLVGAAVVL 271
Query: 772 NASWWFIDIAQFLYIISGTCGRAWTGFSMKAFENLWGFVRLSIASAVMLCLETWYFMALI 951
N S W A F YI+SG+CG+AW+GFS KAF+NLW FV+LS+ASAVMLCLE WYFM LI
Sbjct: 272 NVSSWLPVAANFSYILSGSCGQAWSGFSSKAFQNLWAFVKLSLASAVMLCLEVWYFMVLI 331
Query: 952 LFAGYLKNPEVSVDGLSICTNILGWTIMVSIGFNASTSVRVANELGANHPRTAKFSIAVV 1131
LFAGYLKN EVSVD LSIC ILGW +M+SIGFNA+ SVRV+NELGA+HPRTAKFS+AV
Sbjct: 332 LFAGYLKNAEVSVDALSICMTILGWAVMLSIGFNAAVSVRVSNELGASHPRTAKFSVAVA 391
Query: 1132 VITSFXXXXXXXXXXXXARKQYPYAFTSNADVRNLVYQLTPLLATSILLNMVQPVLSGVA 1311
ITSF AR+QYP F+SNA+++ LVY LTPLLA I++N +QPVLSGVA
Sbjct: 392 AITSFLISVVLSLILIAARRQYPDLFSSNAEIKKLVYSLTPLLAVCIVINNIQPVLSGVA 451
Query: 1312 IGAGWQALVAYVNIACYYLFGIPFGLIMGYALDFGVKGIWCGMITGTVVQTCILFFITYR 1491
+GAGWQA +AYVNI CYY+ G+P GL++G+ LD GVKGIWCGM++GTV+QTCILF + YR
Sbjct: 452 VGAGWQAFIAYVNIGCYYVIGVPMGLLLGFKLDLGVKGIWCGMLSGTVIQTCILFGMIYR 511
Query: 1492 TKWDKEASAAGARIQQWRG 1548
T W+ EAS A RI++W G
Sbjct: 512 TNWNTEASMAEERIRKWGG 530
>ref|XP_002272174.1| PREDICTED: protein TRANSPARENT TESTA 12-like [Vitis vinifera]
Length = 544
Score = 716 bits (1847), Expect = 0.0
Identities = 356/522 (68%), Positives = 416/522 (79%)
Frame = +1
Query: 13 HICESPKPINMEGANQVPLLLHRGDHEDISRQPLKHNGSSFDASLIADGDIEPVKNVNDF 192
H ES +N+ + PLL R D E +R ++F+A + DI P+ V DF
Sbjct: 28 HFSES---LNIMENGKQPLLSARQDDETPNRTAANSLLATFNAD---ESDIGPINGVRDF 81
Query: 193 FREFAVESKKLWFLAGPAIFTSVCQYTLGAVTQAFAGQVGTLELAAVSIENSVIAGFSLG 372
++EF VESKKLW+LAGPAIFTS+CQY+LGA+TQ FAG VGTLELAAVS+ENSVIAGFS G
Sbjct: 82 YKEFIVESKKLWYLAGPAIFTSLCQYSLGAITQVFAGHVGTLELAAVSVENSVIAGFSFG 141
Query: 373 VMMGMGSALETLCGQAFGAGQLDMLGIYMQRSWVILDVTALLLVFLYIFAAQILKLIGQE 552
VM+GMGSALETLCGQAFGAGQLDMLG+YMQRSWVIL TA+LL FLYIF+A++LKLIGQ
Sbjct: 142 VMLGMGSALETLCGQAFGAGQLDMLGVYMQRSWVILTSTAVLLSFLYIFSARLLKLIGQT 201
Query: 553 ENIAETAGKLAIWMIPQLFAYAVNFPQAKFLQAQSKMLVMAIIAFAALVFHTFFSWLFML 732
E I++ AG A+WM+PQLFAYAVNFP AKFLQAQSK++VMA+IA LV HT FSWL ML
Sbjct: 202 EAISKEAGMFAVWMLPQLFAYAVNFPLAKFLQAQSKIMVMAVIAAVVLVLHTVFSWLLML 261
Query: 733 KLGWGLAGAAVVLNASWWFIDIAQFLYIISGTCGRAWTGFSMKAFENLWGFVRLSIASAV 912
KL WGL GAAVVLNASW ID+AQ LYI SGTCGRAWTGFS KAF++LWGFVRLS+ASAV
Sbjct: 262 KLQWGLVGAAVVLNASWVLIDVAQLLYIFSGTCGRAWTGFSWKAFQSLWGFVRLSLASAV 321
Query: 913 MLCLETWYFMALILFAGYLKNPEVSVDGLSICTNILGWTIMVSIGFNASTSVRVANELGA 1092
MLCLE WYFMALILFAGYLKN E+SVD LSIC NILGWT+MV++G NA+ SVRV+NELGA
Sbjct: 322 MLCLEVWYFMALILFAGYLKNAEISVDALSICMNILGWTVMVALGCNAAISVRVSNELGA 381
Query: 1093 NHPRTAKFSIAVVVITSFXXXXXXXXXXXXARKQYPYAFTSNADVRNLVYQLTPLLATSI 1272
HPRTAKF++ VVVITSF RKQYP F+ + +V LV +LTPLLA I
Sbjct: 382 THPRTAKFAVVVVVITSFLIGLVLSAILIIFRKQYPALFSDSEEVEELVDELTPLLAFCI 441
Query: 1273 LLNMVQPVLSGVAIGAGWQALVAYVNIACYYLFGIPFGLIMGYALDFGVKGIWCGMITGT 1452
++N VQPVLSGVAIGAGWQA VA+VNIACYYLFG+P GL++GY + GVKGIWCGM++GT
Sbjct: 442 VINNVQPVLSGVAIGAGWQAFVAWVNIACYYLFGVPLGLVLGYKVGLGVKGIWCGMLSGT 501
Query: 1453 VVQTCILFFITYRTKWDKEASAAGARIQQWRGKAEDSVNDIE 1578
VVQTC+LF + YRT W+KEAS AG RI++W G ND+E
Sbjct: 502 VVQTCVLFGMVYRTNWNKEASIAGDRIKKWGGNEAGRENDVE 543
>ref|XP_002527924.1| multidrug resistance pump, putative [Ricinus communis]
gi|223532699|gb|EEF34481.1| multidrug resistance pump,
putative [Ricinus communis]
Length = 531
Score = 705 bits (1820), Expect = 0.0
Identities = 343/488 (70%), Positives = 403/488 (82%), Gaps = 1/488 (0%)
Frame = +1
Query: 121 NGSSFDASLIADGD-IEPVKNVNDFFREFAVESKKLWFLAGPAIFTSVCQYTLGAVTQAF 297
N +SF ++ + D D I P+ +FFREF ESKKLW+LAGPAIFTS+CQY+LGAVTQ F
Sbjct: 40 NNNSFSSAFVPDSDDIPPITGFRNFFREFYRESKKLWYLAGPAIFTSICQYSLGAVTQVF 99
Query: 298 AGQVGTLELAAVSIENSVIAGFSLGVMMGMGSALETLCGQAFGAGQLDMLGIYMQRSWVI 477
+GQVGTL+LAAVS+ENSVIAGFS G+M+GMGSALETLCGQA+GA QLDMLGIY+QRSWVI
Sbjct: 100 SGQVGTLDLAAVSVENSVIAGFSFGIMLGMGSALETLCGQAYGAKQLDMLGIYLQRSWVI 159
Query: 478 LDVTALLLVFLYIFAAQILKLIGQEENIAETAGKLAIWMIPQLFAYAVNFPQAKFLQAQS 657
L TA L LY+FAAQILK IGQ I++ AG AIWMIPQLFAYA+NFP AKFLQAQS
Sbjct: 160 LGTTASFLCLLYVFAAQILKSIGQTPAISKAAGVFAIWMIPQLFAYAMNFPMAKFLQAQS 219
Query: 658 KMLVMAIIAFAALVFHTFFSWLFMLKLGWGLAGAAVVLNASWWFIDIAQFLYIISGTCGR 837
K++VMA+IA AALV H FSWL MLKLGWGL GAAVVLNASWWFID+AQFLYIISGTCGR
Sbjct: 220 KIMVMAMIAAAALVLHAVFSWLLMLKLGWGLVGAAVVLNASWWFIDLAQFLYIISGTCGR 279
Query: 838 AWTGFSMKAFENLWGFVRLSIASAVMLCLETWYFMALILFAGYLKNPEVSVDGLSICTNI 1017
AW GFS KAF+NLW FVRLS+ASAVMLCLE WYFMALILFAGYLKN EVSVD LSIC NI
Sbjct: 280 AWNGFSWKAFQNLWSFVRLSLASAVMLCLEVWYFMALILFAGYLKNAEVSVDALSICMNI 339
Query: 1018 LGWTIMVSIGFNASTSVRVANELGANHPRTAKFSIAVVVITSFXXXXXXXXXXXXARKQY 1197
LGWT+M++IG NA+ SVRV+NELGA HPRTAKFS+ V VI+SF +R Y
Sbjct: 340 LGWTVMIAIGMNAAISVRVSNELGAGHPRTAKFSLVVAVISSFLIGVVLSLILFLSRNSY 399
Query: 1198 PYAFTSNADVRNLVYQLTPLLATSILLNMVQPVLSGVAIGAGWQALVAYVNIACYYLFGI 1377
P F+++++V+ LV +LTP+LA I++N VQPVLSGVAIGAGWQA+VAYVNIACYY+FGI
Sbjct: 400 PSLFSNDSEVKELVNELTPVLAACIIINNVQPVLSGVAIGAGWQAIVAYVNIACYYVFGI 459
Query: 1378 PFGLIMGYALDFGVKGIWCGMITGTVVQTCILFFITYRTKWDKEASAAGARIQQWRGKAE 1557
P GLI+GY + +GV+GIW GM++GTVVQTC LF++ Y+T W+KEAS A RI++W G +
Sbjct: 460 PMGLILGYKVGWGVRGIWYGMMSGTVVQTCALFWMIYKTNWNKEASIAEDRIRKWGGHTD 519
Query: 1558 DSVNDIEK 1581
VN+ EK
Sbjct: 520 SGVNNKEK 527
>ref|XP_003551225.1| PREDICTED: protein TRANSPARENT TESTA 12-like [Glycine max]
Length = 509
Score = 683 bits (1762), Expect = 0.0
Identities = 336/504 (66%), Positives = 393/504 (77%), Gaps = 3/504 (0%)
Frame = +1
Query: 85 DHEDISRQPLKHNGSSFDASLI---ADGDIEPVKNVNDFFREFAVESKKLWFLAGPAIFT 255
DHED + L + D +++ DI P+ DF REF ESKKLW+LAGPAIFT
Sbjct: 3 DHEDHTHPLLTPRHHTPDPAVVFTAKSDDIAPIAGAGDFAREFFAESKKLWYLAGPAIFT 62
Query: 256 SVCQYTLGAVTQAFAGQVGTLELAAVSIENSVIAGFSLGVMMGMGSALETLCGQAFGAGQ 435
SVCQY+LGAVTQ F+G V TL LAA+SIENSVIAGF LG+ GMGSALETLCGQA+GAGQ
Sbjct: 63 SVCQYSLGAVTQVFSGHVSTLALAAISIENSVIAGFCLGITFGMGSALETLCGQAYGAGQ 122
Query: 436 LDMLGIYMQRSWVILDVTALLLVFLYIFAAQILKLIGQEENIAETAGKLAIWMIPQLFAY 615
+ MLG+YMQRSWVIL+ TA+LL LYIFAA +L+ IGQ E I+ AG A+WMIPQLFAY
Sbjct: 123 VHMLGVYMQRSWVILNATAILLTLLYIFAAPLLRAIGQTEAISAAAGDFAVWMIPQLFAY 182
Query: 616 AVNFPQAKFLQAQSKMLVMAIIAFAALVFHTFFSWLFMLKLGWGLAGAAVVLNASWWFID 795
AVN+P KFLQAQS+++VMA IA AALV HT FSWL MLKL WGL GAAVVLNASWWFID
Sbjct: 183 AVNYPAQKFLQAQSRIMVMAWIAAAALVLHTVFSWLLMLKLRWGLVGAAVVLNASWWFID 242
Query: 796 IAQFLYIISGTCGRAWTGFSMKAFENLWGFVRLSIASAVMLCLETWYFMALILFAGYLKN 975
+AQ +YI+ G CG AW+GF+ KAF NLWGFVRLS+ASAVMLCLE WYFMALILFAGYLKN
Sbjct: 243 LAQLVYIMGGACGEAWSGFTFKAFHNLWGFVRLSLASAVMLCLEVWYFMALILFAGYLKN 302
Query: 976 PEVSVDGLSICTNILGWTIMVSIGFNASTSVRVANELGANHPRTAKFSIAVVVITSFXXX 1155
EVSVD LSIC NILGWTIMVS G NA+ SVRV+NELGA HPRTAKFS+ V VITS
Sbjct: 303 AEVSVDALSICMNILGWTIMVSFGMNAAVSVRVSNELGACHPRTAKFSLLVAVITSTLIG 362
Query: 1156 XXXXXXXXXARKQYPYAFTSNADVRNLVYQLTPLLATSILLNMVQPVLSGVAIGAGWQAL 1335
R QYP+ F+++++VR +V +LTP+LA I++N VQPVLSGVA+GAGWQA+
Sbjct: 363 VMLSMVLIIFRNQYPFLFSNDSEVRKIVVELTPMLALCIVINNVQPVLSGVAVGAGWQAV 422
Query: 1336 VAYVNIACYYLFGIPFGLIMGYALDFGVKGIWCGMITGTVVQTCILFFITYRTKWDKEAS 1515
VAYVNIACYY FGIP GLI+GY LD GV GIW GM+ GT++QTC+LFF+ YRT W+KEAS
Sbjct: 423 VAYVNIACYYFFGIPLGLILGYKLDKGVMGIWSGMLLGTILQTCVLFFMVYRTDWNKEAS 482
Query: 1516 AAGARIQQWRGKAEDSVNDIEKKN 1587
A RI+QW G + + I K +
Sbjct: 483 LAEDRIKQWGGHEDSKTHAIAKND 506
>ref|XP_003628949.1| Protein TRANSPARENT TESTA [Medicago truncatula]
gi|355522971|gb|AET03425.1| Protein TRANSPARENT TESTA
[Medicago truncatula]
Length = 512
Score = 679 bits (1751), Expect = 0.0
Identities = 328/471 (69%), Positives = 385/471 (81%)
Frame = +1
Query: 160 DIEPVKNVNDFFREFAVESKKLWFLAGPAIFTSVCQYTLGAVTQAFAGQVGTLELAAVSI 339
DI P+ DF REF ESKKLW+LAGPAIFTS+ QY+LGAVTQ FAGQVGTL+LAAVS+
Sbjct: 34 DISPITGAGDFAREFLNESKKLWYLAGPAIFTSISQYSLGAVTQVFAGQVGTLQLAAVSV 93
Query: 340 ENSVIAGFSLGVMMGMGSALETLCGQAFGAGQLDMLGIYMQRSWVILDVTALLLVFLYIF 519
ENSVIAGF LG+ MGMGSALETLCGQAFGAG+LDMLGIYMQRSW+IL+ TA++L FLYIF
Sbjct: 94 ENSVIAGFCLGITMGMGSALETLCGQAFGAGKLDMLGIYMQRSWLILNATAIILCFLYIF 153
Query: 520 AAQILKLIGQEENIAETAGKLAIWMIPQLFAYAVNFPQAKFLQAQSKMLVMAIIAFAALV 699
A+ +LKLIGQ I+E AG A+WMIPQLFAYA+NFP KFLQAQSK++ MA I+ AALV
Sbjct: 154 ASPLLKLIGQTTAISEAAGVFALWMIPQLFAYAMNFPIQKFLQAQSKIMAMAWISAAALV 213
Query: 700 FHTFFSWLFMLKLGWGLAGAAVVLNASWWFIDIAQFLYIISGTCGRAWTGFSMKAFENLW 879
HTFFSW ML LGWGL GAAVVLN+SWWFI +AQ +Y++SG+CG AW+GFS +AF+NLW
Sbjct: 214 GHTFFSWFLMLHLGWGLVGAAVVLNSSWWFIVLAQIVYVLSGSCGEAWSGFSFQAFQNLW 273
Query: 880 GFVRLSIASAVMLCLETWYFMALILFAGYLKNPEVSVDGLSICTNILGWTIMVSIGFNAS 1059
GFVRLS+ASAVM+CLE WYFMALILFAGYL+N EVSVD LSICTNILGWT+M S G NA+
Sbjct: 274 GFVRLSLASAVMMCLEVWYFMALILFAGYLENAEVSVDALSICTNILGWTVMASFGVNAA 333
Query: 1060 TSVRVANELGANHPRTAKFSIAVVVITSFXXXXXXXXXXXXARKQYPYAFTSNADVRNLV 1239
SVRV+NELGA+HPR AKFS+ V VITSF RKQYP F+++ +VR +V
Sbjct: 334 VSVRVSNELGASHPRAAKFSLVVAVITSFALGLILSMILIIFRKQYPVLFSNDPEVREVV 393
Query: 1240 YQLTPLLATSILLNMVQPVLSGVAIGAGWQALVAYVNIACYYLFGIPFGLIMGYALDFGV 1419
+LTP+LA I++N +QPVLSGVAIGAGWQ+ VAYVNIACYYLFGIP GL GY LDFGV
Sbjct: 394 IELTPMLALCIVINNIQPVLSGVAIGAGWQSAVAYVNIACYYLFGIPLGLFFGYYLDFGV 453
Query: 1420 KGIWCGMITGTVVQTCILFFITYRTKWDKEASAAGARIQQWRGKAEDSVND 1572
GIW GM++GTV+QT +LFF+ YRT W+ EAS A RI +W G+ +ND
Sbjct: 454 LGIWSGMLSGTVLQTLVLFFMVYRTDWNNEASLAEERISKWGGQKVIKMND 504