BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Coptis21_contig00005005
         (1918 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002276088.2| PREDICTED: bifunctional purine biosynthesis ...   942   0.0  
gb|AAO40252.1| aminoimidazolecarboximide ribonucleotide transfor...   933   0.0  
gb|AAG40879.1|AF321497_1 phosphoribosylaminoimidazolecarboxamide...   931   0.0  
ref|XP_002530710.1| bifunctional purine biosynthesis protein, pu...   930   0.0  
ref|XP_002314814.1| aminoimidazolecarboximide ribonucleotide tra...   925   0.0  

>ref|XP_002276088.2| PREDICTED: bifunctional purine biosynthesis protein PurH-like [Vitis
            vinifera] gi|297737998|emb|CBI27199.3| unnamed protein
            product [Vitis vinifera]
          Length = 604

 Score =  942 bits (2435), Expect = 0.0
 Identities = 474/562 (84%), Positives = 507/562 (90%), Gaps = 4/562 (0%)
 Frame = +2

Query: 89   FYIASVSRSNNVRLVKAMAGAEQTT----RSYSSGPGEKQALISLSDKKDLAFLGNGLQG 256
            + I+S S  +N   VKAMA A+  +    +S S+  G KQALISLSDKKDLAFLGNGLQ 
Sbjct: 44   YRISSPSLRSNFCAVKAMAEADTISILKAQSQSNASGNKQALISLSDKKDLAFLGNGLQS 103

Query: 257  LGFTIVSTGGTASALEEAGVPVTKVEQLTGFPEMLDGRVKTLHPKVHGGILARRDLKHHM 436
            LG+TIVSTGGTASALE AGV VTKVEQLT FPEMLDGRVKTLHP +HGGILARRD K HM
Sbjct: 104  LGYTIVSTGGTASALENAGVSVTKVEQLTCFPEMLDGRVKTLHPNIHGGILARRDQKLHM 163

Query: 437  EALKEHEIGTFDVVVVNLYPFYDKVSSTSGISFEDGIENIDIGGPAMIRAAAKNHRDVLV 616
            EAL EH IGTFDVVVVNLYPFYDKVSS  GI FEDGIENIDIGGPAMIRAAAKNH+DVLV
Sbjct: 164  EALNEHGIGTFDVVVVNLYPFYDKVSS-GGIEFEDGIENIDIGGPAMIRAAAKNHKDVLV 222

Query: 617  VVDPNDYHELLEYLKGNQGDEWFHRKLAWKAFEHVSSYDSAVSEWLWKQTGIDEFPPKFT 796
            VVD  DY  LLE+L+GNQ D+ F RKLAWKAF+HV+SYDSAVSEWLWKQT  D+FPP  T
Sbjct: 223  VVDSQDYSALLEFLQGNQDDQLFRRKLAWKAFQHVASYDSAVSEWLWKQTVGDKFPPSLT 282

Query: 797  VPLSLKSSLRYGENPHQKAAFYVDKRLSEVQAGGIATAIQHHGKEMSYNNYLDADAAWNC 976
            VPLSLKSSLRYGENPHQKAAFYVDK LSEV AGGIATAIQHHGKEMSYNNYLDADAAWNC
Sbjct: 283  VPLSLKSSLRYGENPHQKAAFYVDKSLSEVNAGGIATAIQHHGKEMSYNNYLDADAAWNC 342

Query: 977  VSEFEKPTCVIVKHTNPCGVASRENILEAYRLAVKADPVSAFGGIVAFNVEVDEALAKDI 1156
            VSEF+ PTCVIVKHTNPCGVASR++ILEAYRLAVKADPVSAFGGIVAFN+EVDEALAK+I
Sbjct: 343  VSEFKNPTCVIVKHTNPCGVASRDDILEAYRLAVKADPVSAFGGIVAFNIEVDEALAKEI 402

Query: 1157 REFRSPADGETRMFYEIVVAPKYSEKGLEILRGKSKTLRILEANKNKQGKLSLRQVGGGW 1336
            REFRSP DGETRMFYEIVVAPKYS+KGL+ILRGKSKTLRILEA KN++GKLSLRQVGGGW
Sbjct: 403  REFRSPTDGETRMFYEIVVAPKYSQKGLDILRGKSKTLRILEAGKNEKGKLSLRQVGGGW 462

Query: 1337 LVQDSDDLTPQDIQFKVVSERTPLENELHDAEFAWLCVKHVKSNAIVIAKDDCMLGMGSG 1516
            L QDSDDLTP+DI FK+VSE+ P E+EL DAEFAWLCVKHVKSNAIVIAK++CMLGMGSG
Sbjct: 463  LAQDSDDLTPEDIPFKLVSEKAPPESELRDAEFAWLCVKHVKSNAIVIAKNNCMLGMGSG 522

Query: 1517 QPNRVESLRIALRKAGDEVKGAALASDAFFPFAWNDAVEEACKSGIGAIAEPGGSIRDND 1696
            QPNR ESLRIA+RKAGDEVKGAALASDAFFPFAW DAVEEAC+SGIG IAEPGGSIRD D
Sbjct: 523  QPNRRESLRIAVRKAGDEVKGAALASDAFFPFAWKDAVEEACESGIGIIAEPGGSIRDGD 582

Query: 1697 AIDCCNKYGVSLLFTNVRHFRH 1762
            AIDCCNKYGVSLLFTNVRHFRH
Sbjct: 583  AIDCCNKYGVSLLFTNVRHFRH 604


>gb|AAO40252.1| aminoimidazolecarboximide ribonucleotide transformylase/inosine
            monophosphate cyclohydrolase [Vigna unguiculata]
          Length = 612

 Score =  933 bits (2411), Expect = 0.0
 Identities = 472/578 (81%), Positives = 512/578 (88%), Gaps = 11/578 (1%)
 Frame = +2

Query: 62   HSLQTP-SFSFYIASVS--RSNNVRL----VKAMAG----AEQTTRSYSSGPGEKQALIS 208
            + L TP +FS ++ S +  RS+++      +KAMA     A     S SS PG KQALIS
Sbjct: 35   YPLTTPHNFSSHLLSKTLVRSSSLHFRGVPIKAMAETDTIAASKIASSSSVPGTKQALIS 94

Query: 209  LSDKKDLAFLGNGLQGLGFTIVSTGGTASALEEAGVPVTKVEQLTGFPEMLDGRVKTLHP 388
            LSDKKDLAF+GNGLQ LG+TIVSTGGTASALE+AGV VTKVEQLT FPEMLDGRVKTLHP
Sbjct: 95   LSDKKDLAFVGNGLQELGYTIVSTGGTASALEKAGVAVTKVEQLTQFPEMLDGRVKTLHP 154

Query: 389  KVHGGILARRDLKHHMEALKEHEIGTFDVVVVNLYPFYDKVSSTSGISFEDGIENIDIGG 568
             +HGGILARRDLKHH+EAL  H IGTFDVVVVNLYPFYDKV++  GI FEDGIENIDIGG
Sbjct: 155  NIHGGILARRDLKHHIEALNTHGIGTFDVVVVNLYPFYDKVTAAGGIEFEDGIENIDIGG 214

Query: 569  PAMIRAAAKNHRDVLVVVDPNDYHELLEYLKGNQGDEWFHRKLAWKAFEHVSSYDSAVSE 748
            PAMIRAAAKNH+DVLVVVD  DY  LLE+LKGNQ DE F  KLA KAF+HV+SYDSAVSE
Sbjct: 215  PAMIRAAAKNHKDVLVVVDTEDYPALLEFLKGNQDDEKFRLKLAXKAFQHVASYDSAVSE 274

Query: 749  WLWKQTGIDEFPPKFTVPLSLKSSLRYGENPHQKAAFYVDKRLSEVQAGGIATAIQHHGK 928
            WLWKQ+  D+FPP  TVPLSLKSSLRYGENPHQKAAFYVDK+LSEV AGGIATAIQHHGK
Sbjct: 275  WLWKQSVGDKFPPSLTVPLSLKSSLRYGENPHQKAAFYVDKKLSEVNAGGIATAIQHHGK 334

Query: 929  EMSYNNYLDADAAWNCVSEFEKPTCVIVKHTNPCGVASRENILEAYRLAVKADPVSAFGG 1108
            EMSYNNYLDADAAWNCV EF+ PTCV+VKHTNPCGVASR++ILEAYRLAVKADPVSAFGG
Sbjct: 335  EMSYNNYLDADAAWNCVCEFKNPTCVVVKHTNPCGVASRDDILEAYRLAVKADPVSAFGG 394

Query: 1109 IVAFNVEVDEALAKDIREFRSPADGETRMFYEIVVAPKYSEKGLEILRGKSKTLRILEAN 1288
            IVAFNVE+DEALAK+IREFRSP DGETRMFYEIVVAP Y+EKGLEILRGKSKTLRILEA 
Sbjct: 395  IVAFNVEIDEALAKEIREFRSPTDGETRMFYEIVVAPSYTEKGLEILRGKSKTLRILEAK 454

Query: 1289 KNKQGKLSLRQVGGGWLVQDSDDLTPQDIQFKVVSERTPLENELHDAEFAWLCVKHVKSN 1468
            KN+ GKLSLRQVGGGWL QDSDDLTPQDI+F VVS + P ++EL DAEFAWLCVKHVKSN
Sbjct: 455  KNEPGKLSLRQVGGGWLAQDSDDLTPQDIKFNVVSGKAPQDDELRDAEFAWLCVKHVKSN 514

Query: 1469 AIVIAKDDCMLGMGSGQPNRVESLRIALRKAGDEVKGAALASDAFFPFAWNDAVEEACKS 1648
            AIVIAK++CMLGMGSGQPNRVESLRIA+RKAGD+VKGAALASDAFFPFAW DAVEEAC+S
Sbjct: 515  AIVIAKNNCMLGMGSGQPNRVESLRIAMRKAGDDVKGAALASDAFFPFAWKDAVEEACES 574

Query: 1649 GIGAIAEPGGSIRDNDAIDCCNKYGVSLLFTNVRHFRH 1762
            GIG IAEPGGSIRD DAIDCCNKYGVSLLFTNVRHFRH
Sbjct: 575  GIGVIAEPGGSIRDQDAIDCCNKYGVSLLFTNVRHFRH 612


>gb|AAG40879.1|AF321497_1 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP
            cyclohydrolase [Nicotiana tabacum]
          Length = 612

 Score =  931 bits (2407), Expect = 0.0
 Identities = 471/588 (80%), Positives = 515/588 (87%), Gaps = 6/588 (1%)
 Frame = +2

Query: 17   ASAVRLCHPQTYNYCHSLQT-PSFSFYIASVSRSNN---VRLVKAMAGAEQTTRSY--SS 178
            A+ V LC PQ      +++T  SF F     S++++   V  VKAMA       S   SS
Sbjct: 29   AATVHLCTPQL----RTIRTRTSFCFGQQQSSKTSHRVMVYPVKAMAETAAAPHSAPKSS 84

Query: 179  GPGEKQALISLSDKKDLAFLGNGLQGLGFTIVSTGGTASALEEAGVPVTKVEQLTGFPEM 358
              G KQALISLSDK DLA LGNGLQ LG+TIVSTGGT+SALE AGV VTKVE+LT FPEM
Sbjct: 85   TSGRKQALISLSDKTDLAKLGNGLQELGYTIVSTGGTSSALEGAGVSVTKVEELTRFPEM 144

Query: 359  LDGRVKTLHPKVHGGILARRDLKHHMEALKEHEIGTFDVVVVNLYPFYDKVSSTSGISFE 538
            LDGRVKTLHP VHGGILARRD +HHMEAL++HEIGTFDVVVVNLYPFY KVSS+SGISFE
Sbjct: 145  LDGRVKTLHPSVHGGILARRDQEHHMEALEKHEIGTFDVVVVNLYPFYAKVSSSSGISFE 204

Query: 539  DGIENIDIGGPAMIRAAAKNHRDVLVVVDPNDYHELLEYLKGNQGDEWFHRKLAWKAFEH 718
            DGIENIDIGGPAMIRAAAKNHRDVLVVVD  DY  LLE+L+G+  D+ F RKLAWKAF+H
Sbjct: 205  DGIENIDIGGPAMIRAAAKNHRDVLVVVDSEDYPALLEFLRGDNDDQQFRRKLAWKAFQH 264

Query: 719  VSSYDSAVSEWLWKQTGIDEFPPKFTVPLSLKSSLRYGENPHQKAAFYVDKRLSEVQAGG 898
            V+SYDSAVSEWLWKQT  D+FPP  TVPL LKS LRYGENPHQKAA YVDK LSEV AGG
Sbjct: 265  VASYDSAVSEWLWKQTVGDKFPPGLTVPLHLKSLLRYGENPHQKAAVYVDKSLSEVNAGG 324

Query: 899  IATAIQHHGKEMSYNNYLDADAAWNCVSEFEKPTCVIVKHTNPCGVASRENILEAYRLAV 1078
            IAT IQHHGKEMSYNNYLDADAAWNCV EF KPTCV+VKHTNPCGVASR +I+EAYRLAV
Sbjct: 325  IATVIQHHGKEMSYNNYLDADAAWNCVCEFNKPTCVVVKHTNPCGVASRNDIIEAYRLAV 384

Query: 1079 KADPVSAFGGIVAFNVEVDEALAKDIREFRSPADGETRMFYEIVVAPKYSEKGLEILRGK 1258
            KADPVSAFGGIVAFNVEVDEALAKDIREFRSP DGETRMFYEIVVAPKY+EKGLE+LRGK
Sbjct: 385  KADPVSAFGGIVAFNVEVDEALAKDIREFRSPTDGETRMFYEIVVAPKYTEKGLEVLRGK 444

Query: 1259 SKTLRILEANKNKQGKLSLRQVGGGWLVQDSDDLTPQDIQFKVVSERTPLENELHDAEFA 1438
            SKTLRILEA+KN +GKLSLRQ+GGGWL QDSDDLTP+DIQF V+S++TP ENEL+DA+FA
Sbjct: 445  SKTLRILEASKNSKGKLSLRQIGGGWLAQDSDDLTPEDIQFNVMSDKTPQENELNDAQFA 504

Query: 1439 WLCVKHVKSNAIVIAKDDCMLGMGSGQPNRVESLRIALRKAGDEVKGAALASDAFFPFAW 1618
            WLCVKHVKSNAIVIAK++CMLGMGSGQPNR+ESLRIA+RKAGDEVKGAALASDAFFPFAW
Sbjct: 505  WLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIAMRKAGDEVKGAALASDAFFPFAW 564

Query: 1619 NDAVEEACKSGIGAIAEPGGSIRDNDAIDCCNKYGVSLLFTNVRHFRH 1762
            NDAVEEAC+SG+  IAEPGGSIRD DA+DCCNKYGVSL+FTNVRHFRH
Sbjct: 565  NDAVEEACQSGVSVIAEPGGSIRDKDAVDCCNKYGVSLVFTNVRHFRH 612


>ref|XP_002530710.1| bifunctional purine biosynthesis protein, putative [Ricinus communis]
            gi|223529724|gb|EEF31664.1| bifunctional purine
            biosynthesis protein, putative [Ricinus communis]
          Length = 617

 Score =  930 bits (2403), Expect = 0.0
 Identities = 456/548 (83%), Positives = 498/548 (90%), Gaps = 4/548 (0%)
 Frame = +2

Query: 131  VKAMAGAEQTTRS----YSSGPGEKQALISLSDKKDLAFLGNGLQGLGFTIVSTGGTASA 298
            VKAMA ++  + S     S   G KQALISLSDK+DLA LG GLQ LG+TIVSTGGTAS+
Sbjct: 70   VKAMADSQTLSVSKNQPQSPSSGNKQALISLSDKRDLALLGRGLQNLGYTIVSTGGTASS 129

Query: 299  LEEAGVPVTKVEQLTGFPEMLDGRVKTLHPKVHGGILARRDLKHHMEALKEHEIGTFDVV 478
            LE AGV VTKVEQLT FPEMLDGRVKTLHP +HGGILARRD KHHMEAL EH IGTFDVV
Sbjct: 130  LESAGVSVTKVEQLTSFPEMLDGRVKTLHPNIHGGILARRDQKHHMEALNEHGIGTFDVV 189

Query: 479  VVNLYPFYDKVSSTSGISFEDGIENIDIGGPAMIRAAAKNHRDVLVVVDPNDYHELLEYL 658
            VVNLYPFYDKV+S+  I FEDGIENIDIGGPAMIRAAAKNH+DVLVVVD  DY  LL+YL
Sbjct: 190  VVNLYPFYDKVTSSGQIDFEDGIENIDIGGPAMIRAAAKNHKDVLVVVDSEDYPALLDYL 249

Query: 659  KGNQGDEWFHRKLAWKAFEHVSSYDSAVSEWLWKQTGIDEFPPKFTVPLSLKSSLRYGEN 838
            +G+Q D+ F R LAWKAF+HV+SYDSAVSEWLWKQT  D+FPP  TVPLSLKSSLRYGEN
Sbjct: 250  QGDQDDQQFRRNLAWKAFQHVASYDSAVSEWLWKQTVGDKFPPSLTVPLSLKSSLRYGEN 309

Query: 839  PHQKAAFYVDKRLSEVQAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEFEKPTCVIVKH 1018
            PHQKAAFYVDK +SEV AGGIATAIQHHGKEMSYNNYLDADAAWNCVSEF+ PTCV+VKH
Sbjct: 310  PHQKAAFYVDKSISEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEFKNPTCVVVKH 369

Query: 1019 TNPCGVASRENILEAYRLAVKADPVSAFGGIVAFNVEVDEALAKDIREFRSPADGETRMF 1198
            TNPCGVASR++ILEAYRLAVKADPVSAFGGIVAFN+EVDE LAK+IREFRSP DGETRMF
Sbjct: 370  TNPCGVASRDDILEAYRLAVKADPVSAFGGIVAFNIEVDEVLAKEIREFRSPTDGETRMF 429

Query: 1199 YEIVVAPKYSEKGLEILRGKSKTLRILEANKNKQGKLSLRQVGGGWLVQDSDDLTPQDIQ 1378
            YEIVVAPKY++KGLE+LRGKSKTLRILEA KN+QGKLSLRQVGGGWL QDSDDLTPQDI+
Sbjct: 430  YEIVVAPKYTKKGLEVLRGKSKTLRILEAKKNEQGKLSLRQVGGGWLAQDSDDLTPQDIK 489

Query: 1379 FKVVSERTPLENELHDAEFAWLCVKHVKSNAIVIAKDDCMLGMGSGQPNRVESLRIALRK 1558
            F  +SE+TP E+EL+DA+FAWLCVKHVKSNAIVIAK++CMLGMGSGQPNR+ESLRIAL+K
Sbjct: 490  FNFMSEKTPQESELNDAQFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRIALKK 549

Query: 1559 AGDEVKGAALASDAFFPFAWNDAVEEACKSGIGAIAEPGGSIRDNDAIDCCNKYGVSLLF 1738
            AGDEVKGAALASDAFFPFAWNDAVEEAC++G+G IAEPGGSIRD DAIDCCNKYGVSL+F
Sbjct: 550  AGDEVKGAALASDAFFPFAWNDAVEEACEAGVGVIAEPGGSIRDKDAIDCCNKYGVSLIF 609

Query: 1739 TNVRHFRH 1762
            TNVRHFRH
Sbjct: 610  TNVRHFRH 617


>ref|XP_002314814.1| aminoimidazolecarboximide ribonucleotide transformylase/inosine
            monophosphate cyclohydrolase [Populus trichocarpa]
            gi|222863854|gb|EEF00985.1| aminoimidazolecarboximide
            ribonucleotide transformylase/inosine monophosphate
            cyclohydrolase [Populus trichocarpa]
          Length = 545

 Score =  925 bits (2391), Expect = 0.0
 Identities = 452/530 (85%), Positives = 488/530 (92%)
 Frame = +2

Query: 173  SSGPGEKQALISLSDKKDLAFLGNGLQGLGFTIVSTGGTASALEEAGVPVTKVEQLTGFP 352
            S   G+KQALISLSDKKDLAFLG GL+ LG+TIVSTGGTASALE AGV VTKVEQLT FP
Sbjct: 16   SPASGKKQALISLSDKKDLAFLGTGLEQLGYTIVSTGGTASALEGAGVSVTKVEQLTLFP 75

Query: 353  EMLDGRVKTLHPKVHGGILARRDLKHHMEALKEHEIGTFDVVVVNLYPFYDKVSSTSGIS 532
            EMLDGRVKTLHP +HGGILARRD KHHMEAL EH IG+FDVVVVNLYPFYDKV+ST GI 
Sbjct: 76   EMLDGRVKTLHPHIHGGILARRDQKHHMEALSEHGIGSFDVVVVNLYPFYDKVTSTGGIE 135

Query: 533  FEDGIENIDIGGPAMIRAAAKNHRDVLVVVDPNDYHELLEYLKGNQGDEWFHRKLAWKAF 712
            FEDGIENIDIGGPAMIRAAAKNH+DVL+VVD  DY  LLE+LKG++ D+ F RKLAWKAF
Sbjct: 136  FEDGIENIDIGGPAMIRAAAKNHKDVLIVVDNEDYPGLLEFLKGDRDDQQFRRKLAWKAF 195

Query: 713  EHVSSYDSAVSEWLWKQTGIDEFPPKFTVPLSLKSSLRYGENPHQKAAFYVDKRLSEVQA 892
            +H +SYDSAVSEWLWKQT  D+FPP FTVPL LKSSLRYGENPHQ AAFYVDK +SEV A
Sbjct: 196  QHCASYDSAVSEWLWKQTMGDKFPPSFTVPLELKSSLRYGENPHQNAAFYVDKSISEVNA 255

Query: 893  GGIATAIQHHGKEMSYNNYLDADAAWNCVSEFEKPTCVIVKHTNPCGVASRENILEAYRL 1072
            GGIATAIQHHGKEMSYNNYLDADAAWNCVSEF+ PTCVIVKHTNPCGVASR +ILEAYRL
Sbjct: 256  GGIATAIQHHGKEMSYNNYLDADAAWNCVSEFQNPTCVIVKHTNPCGVASRGDILEAYRL 315

Query: 1073 AVKADPVSAFGGIVAFNVEVDEALAKDIREFRSPADGETRMFYEIVVAPKYSEKGLEILR 1252
            AVK DPVSAFGGIVAFN+EVDEALAK+IREFRSP DGETRMFYEIVVAPKY++KGLEILR
Sbjct: 316  AVKGDPVSAFGGIVAFNIEVDEALAKEIREFRSPTDGETRMFYEIVVAPKYTKKGLEILR 375

Query: 1253 GKSKTLRILEANKNKQGKLSLRQVGGGWLVQDSDDLTPQDIQFKVVSERTPLENELHDAE 1432
            GKSKTLRILEA  N++GKLSLRQVGGGWL QDSDDL PQDIQF VVS+++P E+ELHDAE
Sbjct: 376  GKSKTLRILEAKSNEKGKLSLRQVGGGWLAQDSDDLAPQDIQFNVVSDKSPAESELHDAE 435

Query: 1433 FAWLCVKHVKSNAIVIAKDDCMLGMGSGQPNRVESLRIALRKAGDEVKGAALASDAFFPF 1612
            FAWLC KHVKSNAIVIAK++CMLGMGSGQPNR+ESLRI++RKAGDEVKGAALASDAFFPF
Sbjct: 436  FAWLCAKHVKSNAIVIAKNNCMLGMGSGQPNRLESLRISMRKAGDEVKGAALASDAFFPF 495

Query: 1613 AWNDAVEEACKSGIGAIAEPGGSIRDNDAIDCCNKYGVSLLFTNVRHFRH 1762
            AWNDAVEEAC++GIG IAEPGGSIRD DAI+CCNKYGVSLLFTNVRHFRH
Sbjct: 496  AWNDAVEEACEAGIGVIAEPGGSIRDKDAIECCNKYGVSLLFTNVRHFRH 545