BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Cocculus23_contig00006780
         (2394 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]               783   0.0  
ref|XP_007020666.1| DNA topoisomerase I alpha isoform 3 [Theobro...   767   0.0  
ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobro...   767   0.0  
ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis v...   743   0.0  
dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]             743   0.0  
dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. g...   741   0.0  
dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]       735   0.0  
dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]                 733   0.0  
ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform ...   733   0.0  
dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]             732   0.0  
ref|XP_006452480.1| hypothetical protein CICLE_v10007398mg [Citr...   730   0.0  
ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citr...   730   0.0  
dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]                  730   0.0  
dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]                 729   0.0  
ref|XP_002300344.1| DNA topoisomerase family protein [Populus tr...   729   0.0  
dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]                  724   0.0  
dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]                  723   0.0  
dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]               719   0.0  
ref|XP_002317355.1| DNA topoisomerase family protein [Populus tr...   719   0.0  
dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]              716   0.0  

>dbj|BAG31376.1| topoisomerase I [Camptotheca acuminata]
          Length = 894

 Score =  783 bits (2022), Expect = 0.0
 Identities = 437/742 (58%), Positives = 494/742 (66%), Gaps = 21/742 (2%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV AC+K K   + D E D P++FKR+   SK NQLNS+ K  +S ++DG S R  S  
Sbjct: 1    MAVQACVKEKMMDEID-EDDEPLVFKRSNATSKHNQLNSDTKK-SSQRYDGQSGRQVSDV 58

Query: 1983 PSPSGQ-------KTQNSSTQKGN------AVSSANTSSIANSKLPPAGNDKSKRSMGES 1843
            PS +GQ       KT   S+ K        + S A  S +AN K+  + +D+SK S  ++
Sbjct: 59   PSTNGQSSSASKGKTTKLSSMKSPIASPKASTSFAKASPVANPKVSSSSDDRSKHSSKQN 118

Query: 1842 SKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKRLKS------P 1681
            +     E+K L  P+ +P         +KPLS RL T L+K +S+ A K L +      P
Sbjct: 119  TINVVKEEKELVNPAAEP---YGDSEDEKPLSARLFTGLTKGSSNNANKGLINSSPASLP 175

Query: 1680 IPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEEKPLASRFQQN 1501
            +P P +                 EIPLSSKFR           S++SD+ K L S FQQN
Sbjct: 176  VPKPEI--------NRYSDDSDDEIPLSSKFRLKANAGTSTVKSYESDDNKTLVSNFQQN 227

Query: 1500 GSSKSNEMMGLKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXXXXAEPKMDD--D 1327
            GS        +KV NKRP     SS QSS+KKPKLSD             AEPK DD  D
Sbjct: 228  GSINRGSKSSIKV-NKRPLGEVKSSVQSSVKKPKLSDASTPVNNKQASKKAEPKADDSDD 286

Query: 1326 DHVPIGQRMKKPVASDNKLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGS 1147
            DHVPI QRMKK   S NK                              KYSKS+KVPP S
Sbjct: 287  DHVPISQRMKKSATSGNKSSTAKQKVTKVVSSSMKKASKKFKKVVKKSKYSKSSKVPPSS 346

Query: 1146 GEGQKWTTLVHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPR 967
            GEG+KW TLVHNGVIFPPPYKPHGVKMLY G+PVDLTPEQEEVATMFAVM DTDY TK +
Sbjct: 347  GEGKKWNTLVHNGVIFPPPYKPHGVKMLYKGKPVDLTPEQEEVATMFAVMLDTDYMTKSK 406

Query: 966  FIENFMNDWRQILGRNHVIKKFELCDFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXX 787
            F ENFM+DWR+ILG+NHVI+  E CDFT IYEWHQ+EK+KKK+M+               
Sbjct: 407  FKENFMDDWRKILGKNHVIQNLEDCDFTPIYEWHQREKEKKKKMTAEEKKVLKEERLKQE 466

Query: 786  XKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPEC 607
             KYMWAIV+GVKEKVGNFRVEPP LFRGRGEHPKMGKLKK IRPSDITINIGK+APIPEC
Sbjct: 467  EKYMWAIVNGVKEKVGNFRVEPPSLFRGRGEHPKMGKLKKCIRPSDITINIGKDAPIPEC 526

Query: 606  PISGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDY 427
            PI GE WKE++HDNTVTWLAFWNDPI P+EFKYVFLAASSSLKGQSDKEKYEKARLLKD+
Sbjct: 527  PIPGESWKEIRHDNTVTWLAFWNDPIKPREFKYVFLAASSSLKGQSDKEKYEKARLLKDF 586

Query: 426  IHNIRANYTKDFTSKDATKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSL 247
            I  IRA YTKDF SKD TKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV  
Sbjct: 587  IQGIRAAYTKDFASKDITKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEP 646

Query: 246  GDQYKLQFDFLGKDSIRYFNTVEVEPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKE 67
                 L+FDFLGKDSIRY N VEVE PVYKAI QFR+            DT+KLNAHLK 
Sbjct: 647  KPPSILKFDFLGKDSIRYQNEVEVELPVYKAIQQFRTGKRGGDDLFDKLDTSKLNAHLKG 706

Query: 66   LMPGLTAKVFRTYNASITLDDM 1
            LMPGLTAKVFRTYNASITLD+M
Sbjct: 707  LMPGLTAKVFRTYNASITLDEM 728


>ref|XP_007020666.1| DNA topoisomerase I alpha isoform 3 [Theobroma cacao]
            gi|590606159|ref|XP_007020668.1| DNA topoisomerase I
            alpha isoform 3 [Theobroma cacao]
            gi|508720294|gb|EOY12191.1| DNA topoisomerase I alpha
            isoform 3 [Theobroma cacao] gi|508720296|gb|EOY12193.1|
            DNA topoisomerase I alpha isoform 3 [Theobroma cacao]
          Length = 836

 Score =  767 bits (1980), Expect = 0.0
 Identities = 425/747 (56%), Positives = 494/747 (66%), Gaps = 26/747 (3%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPAS-KQNQLNSEIKNLTSPKHDGSSQRHTSG 1987
            MAV+A  K  +  D DD+ DGPV+FKRN  +S KQNQLNSE+K  +S + DG S R  S 
Sbjct: 1    MAVEAPAKHVYDFD-DDDDDGPVVFKRNNTSSSKQNQLNSEVKKASSQRSDGQSGRQVSD 59

Query: 1986 APSPSGQ-----KTQNSSTQKGNAVSS------ANTSS---------IANSKLPPAGNDK 1867
              SP+GQ     K ++ S+ K   V S      A+TSS         + N K   + ND+
Sbjct: 60   VRSPNGQSSNAPKNKSISSSKSPPVKSPILSPKASTSSTKALPVKSPVVNFKASTSLNDQ 119

Query: 1866 SKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSN---SSPAPK 1696
            SK+++ ++   +  E +   K + +P +         PLS RL    ++ N   S+ AP 
Sbjct: 120  SKQALKQNMTTAVKEGRSPIKGTTEPNSDDDDDDDSLPLSARLKGISNQGNKGASTSAPA 179

Query: 1695 RLKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEEKPLAS 1516
            + +  +P   V                   PLS++F              D DE+KPLAS
Sbjct: 180  QSRRLVPKTEVKVSAEDPDDEA--------PLSARFNVKSNTGTSSSRLHDCDEKKPLAS 231

Query: 1515 RFQQNGSSKSNEMMGLKVLN-KRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXXXXAEPK 1339
            + QQNGS    +      L+ KRP    NSSD SS KKPK SD             AE  
Sbjct: 232  KIQQNGSIMKGKQQNSSTLSGKRPLDKGNSSDHSSAKKPKTSDAPTTMKTKQVTVKAEKA 291

Query: 1338 MDDDDHVPIGQRMKKPVASDNKLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXKYSKSTKV 1159
             +DDDH+PI QRMKK  AS++KL                             KY KSTKV
Sbjct: 292  DEDDDHMPIAQRMKKSTASNSKLSSMKQKTTKVVSSSFKKINKKSKKEMKSSKYIKSTKV 351

Query: 1158 PPGSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDY 982
            PP SG+GQK W+TLVHNGVIFP PY PHGVKMLY+G+PVDLTPEQEEVATMFAVMKDTDY
Sbjct: 352  PPSSGDGQKKWSTLVHNGVIFPSPYTPHGVKMLYDGRPVDLTPEQEEVATMFAVMKDTDY 411

Query: 981  ATKPRFIENFMNDWRQILGRNHVIKKFELCDFTAIYEWHQKEKDKKKQMSTXXXXXXXXX 802
             +K +F +NF  DW ++LG+NH IK  + CDFT IYEWH +EK+KKKQMS+         
Sbjct: 412  MSKTQFKKNFWEDWSKLLGKNHTIKDLDRCDFTPIYEWHLQEKEKKKQMSSEEKKALKEE 471

Query: 801  XXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKNA 622
                  K+MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIGK+A
Sbjct: 472  KLKQEEKFMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDA 531

Query: 621  PIPECPISGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 442
            PIPECPI GERWK++KHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR
Sbjct: 532  PIPECPIPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 591

Query: 441  LLKDYIHNIRANYTKDFTSKDATKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 262
            +LKDYI NIRA YTKDFT+KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 592  MLKDYIKNIRAAYTKDFTTKDVMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 651

Query: 261  ENVSLGDQYKLQFDFLGKDSIRYFNTVEVEPPVYKAIGQFRSXXXXXXXXXXXXDTNKLN 82
             NV      KL+FDFLGKDSI+Y NTVEVE PVYKAIGQF++            DT+KLN
Sbjct: 652  GNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKSKSDDLFDKLDTSKLN 711

Query: 81   AHLKELMPGLTAKVFRTYNASITLDDM 1
            AHLKELMPGLTAKVFRTYNASITLD+M
Sbjct: 712  AHLKELMPGLTAKVFRTYNASITLDEM 738


>ref|XP_007020664.1| DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
            gi|590606147|ref|XP_007020665.1| DNA topoisomerase I
            alpha isoform 1 [Theobroma cacao]
            gi|508720292|gb|EOY12189.1| DNA topoisomerase I alpha
            isoform 1 [Theobroma cacao] gi|508720293|gb|EOY12190.1|
            DNA topoisomerase I alpha isoform 1 [Theobroma cacao]
          Length = 904

 Score =  767 bits (1980), Expect = 0.0
 Identities = 425/747 (56%), Positives = 494/747 (66%), Gaps = 26/747 (3%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPAS-KQNQLNSEIKNLTSPKHDGSSQRHTSG 1987
            MAV+A  K  +  D DD+ DGPV+FKRN  +S KQNQLNSE+K  +S + DG S R  S 
Sbjct: 1    MAVEAPAKHVYDFD-DDDDDGPVVFKRNNTSSSKQNQLNSEVKKASSQRSDGQSGRQVSD 59

Query: 1986 APSPSGQ-----KTQNSSTQKGNAVSS------ANTSS---------IANSKLPPAGNDK 1867
              SP+GQ     K ++ S+ K   V S      A+TSS         + N K   + ND+
Sbjct: 60   VRSPNGQSSNAPKNKSISSSKSPPVKSPILSPKASTSSTKALPVKSPVVNFKASTSLNDQ 119

Query: 1866 SKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSN---SSPAPK 1696
            SK+++ ++   +  E +   K + +P +         PLS RL    ++ N   S+ AP 
Sbjct: 120  SKQALKQNMTTAVKEGRSPIKGTTEPNSDDDDDDDSLPLSARLKGISNQGNKGASTSAPA 179

Query: 1695 RLKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEEKPLAS 1516
            + +  +P   V                   PLS++F              D DE+KPLAS
Sbjct: 180  QSRRLVPKTEVKVSAEDPDDEA--------PLSARFNVKSNTGTSSSRLHDCDEKKPLAS 231

Query: 1515 RFQQNGSSKSNEMMGLKVLN-KRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXXXXAEPK 1339
            + QQNGS    +      L+ KRP    NSSD SS KKPK SD             AE  
Sbjct: 232  KIQQNGSIMKGKQQNSSTLSGKRPLDKGNSSDHSSAKKPKTSDAPTTMKTKQVTVKAEKA 291

Query: 1338 MDDDDHVPIGQRMKKPVASDNKLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXKYSKSTKV 1159
             +DDDH+PI QRMKK  AS++KL                             KY KSTKV
Sbjct: 292  DEDDDHMPIAQRMKKSTASNSKLSSMKQKTTKVVSSSFKKINKKSKKEMKSSKYIKSTKV 351

Query: 1158 PPGSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDY 982
            PP SG+GQK W+TLVHNGVIFP PY PHGVKMLY+G+PVDLTPEQEEVATMFAVMKDTDY
Sbjct: 352  PPSSGDGQKKWSTLVHNGVIFPSPYTPHGVKMLYDGRPVDLTPEQEEVATMFAVMKDTDY 411

Query: 981  ATKPRFIENFMNDWRQILGRNHVIKKFELCDFTAIYEWHQKEKDKKKQMSTXXXXXXXXX 802
             +K +F +NF  DW ++LG+NH IK  + CDFT IYEWH +EK+KKKQMS+         
Sbjct: 412  MSKTQFKKNFWEDWSKLLGKNHTIKDLDRCDFTPIYEWHLQEKEKKKQMSSEEKKALKEE 471

Query: 801  XXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKNA 622
                  K+MWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK+RIRPSDITINIGK+A
Sbjct: 472  KLKQEEKFMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKRRIRPSDITINIGKDA 531

Query: 621  PIPECPISGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 442
            PIPECPI GERWK++KHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR
Sbjct: 532  PIPECPIPGERWKDIKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 591

Query: 441  LLKDYIHNIRANYTKDFTSKDATKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 262
            +LKDYI NIRA YTKDFT+KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 592  MLKDYIKNIRAAYTKDFTTKDVMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 651

Query: 261  ENVSLGDQYKLQFDFLGKDSIRYFNTVEVEPPVYKAIGQFRSXXXXXXXXXXXXDTNKLN 82
             NV      KL+FDFLGKDSI+Y NTVEVE PVYKAIGQF++            DT+KLN
Sbjct: 652  GNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKSKSDDLFDKLDTSKLN 711

Query: 81   AHLKELMPGLTAKVFRTYNASITLDDM 1
            AHLKELMPGLTAKVFRTYNASITLD+M
Sbjct: 712  AHLKELMPGLTAKVFRTYNASITLDEM 738


>ref|XP_002265386.1| PREDICTED: DNA topoisomerase 1-like [Vitis vinifera]
          Length = 883

 Score =  743 bits (1919), Expect = 0.0
 Identities = 428/731 (58%), Positives = 475/731 (64%), Gaps = 25/731 (3%)
 Frame = -1

Query: 2118 DDESDGPVIFKRNKPASKQNQLNSEIKNLTSP------------KHDGSSQRHTS-GAPS 1978
            D E D P+  K +    K N  +  +K L+SP            K DG S+      +  
Sbjct: 18   DSEDDKPLSAKLSARLPKGN--SHVLKGLSSPVLQSQKTKVDVKKSDGDSEDEVPLSSKF 75

Query: 1977 PSGQKTQNSSTQKGNAVSSANTSSIANSKLPPAGNDKSKRSMGESSKVSDVEKKRLSKPS 1798
            P     ++SS   G ++ S   +S + S  PP    ++K  + ESS  S+ E        
Sbjct: 76   PLKTYVRSSS---GKSLGSKGLNSPSLSSHPP----ETKVGVKESSDDSEDEI------- 121

Query: 1797 VDPGAXXXXXXXDKPLSIRLSTALSKSNSSPA---PKRLKSPIPSPSVAXXXXXXXXXXX 1627
                          PL ++L     K  SS      K L SP  S   +           
Sbjct: 122  --------------PLLLKLQLKSRKGASSSKLLDSKGLSSPASSRPQSQKAKVNNKNLS 167

Query: 1626 XXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEEKPLASRFQQNGSSKSNE--MMGLKVLNK 1453
                 EIPLSSKFR             + DE+KPL S  + NG SK ++  +   K  NK
Sbjct: 168  DDSEDEIPLSSKFRLKTGMGASLDKLDNFDEKKPLTSTLKPNGISKKDDERVKSPKGQNK 227

Query: 1452 RPSSYANSSDQSSLKKPKLSDGXXXXXXXXXXXXAEPKMDDDD-------HVPIGQRMKK 1294
            RP   AN+S  SS KKPKL DG            AE K DDDD       + P  +R+KK
Sbjct: 228  RPLGQANTSHHSSSKKPKLLDGSVKGKVKQVSVKAEQKDDDDDDNDDDDEYTPTVKRLKK 287

Query: 1293 PVASDNKLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVH 1114
             V+SDNK +                            KYSKSTKVPP SGEGQKWTTL H
Sbjct: 288  SVSSDNK-KASKTKVIPSSRKKATKKAKKSKKLAKSSKYSKSTKVPPNSGEGQKWTTLEH 346

Query: 1113 NGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQ 934
            NGVIFPPPYKPHGVKMLYNG+PVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWR 
Sbjct: 347  NGVIFPPPYKPHGVKMLYNGRPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRV 406

Query: 933  ILGRNHVIKKFELCDFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGV 754
             LG+NHVIKKFELCDFT IYEWH+KEK+KKKQM+T               KYMWA+VDGV
Sbjct: 407  RLGKNHVIKKFELCDFTPIYEWHEKEKEKKKQMTTEEKKALKEEKLKQEDKYMWAVVDGV 466

Query: 753  KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVK 574
            KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI PSDITINIGK AP+PECPI GERWKEV+
Sbjct: 467  KEKVGNFRVEPPGLFRGRGEHPKMGKLKKRICPSDITINIGKEAPVPECPIPGERWKEVR 526

Query: 573  HDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKD 394
            HDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYI NIRA YTKD
Sbjct: 527  HDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIQNIRATYTKD 586

Query: 393  FTSKDATKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFL 214
            FT+KD  KRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV+L    KL+FDFL
Sbjct: 587  FTNKDTMKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVALVPPNKLEFDFL 646

Query: 213  GKDSIRYFNTVEVEPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFR 34
            GKDSIRYFNTVEVE PVYKAIGQF++            DT+KLNAHLKELMPGLTAKVFR
Sbjct: 647  GKDSIRYFNTVEVELPVYKAIGQFKTGKSGGDDLFDKLDTSKLNAHLKELMPGLTAKVFR 706

Query: 33   TYNASITLDDM 1
            TYNASITLD+M
Sbjct: 707  TYNASITLDEM 717


>dbj|BAK32958.1| topoisomerase I [Ophiorrhiza pedunculata]
          Length = 920

 Score =  743 bits (1917), Expect = 0.0
 Identities = 425/778 (54%), Positives = 482/778 (61%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC       D +D+ +GPVIFKR+ PASKQNQ NSE K L+  KH G S  HTS  
Sbjct: 1    MAVEACTTTNLMEDMEDD-EGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDV 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   NSS QKG    SA T  +                       ANSK   +  
Sbjct: 60   RPANGE---NSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASAT 116

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P+    +       +KPLS R     SK  S+ A K 
Sbjct: 117  STAKQQNHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKE 175

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S+DSDE+
Sbjct: 176  GGDSCSIRRPVIEESEDSEDEK-------------PLSRRFTSKSSLGESTSKSYDSDEK 222

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ Q NGS+  +  M     + NKRP     S +QSSLKKPKLS            
Sbjct: 223  KPLAAKVQPNGSASRDSPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 1356 XXAEPKMDDDD-------------------------HVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK +DDD                         +VPI QR+KK  AS +K       
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKK 342

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 402

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFAVM DTDY  KPRF ENF +DW+++LG+NH I+  E C
Sbjct: 403  KMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDC 462

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+EK+KKKQM+T               KYMWAIVDGVKEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPKMGKLKKRIRP DITINIGK+APIPECPI GERWKEV++DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            IN KEFKYVFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDFT +KD  K+QIAV
Sbjct: 583  INQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV       L+FDFLGKDSIRY N V+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQV 702

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 703  EPAVFKAIHQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760


>dbj|BAK32962.1| topoisomerase I [Ophiorrhiza trichocarpon var. glabra]
          Length = 920

 Score =  741 bits (1914), Expect = 0.0
 Identities = 424/778 (54%), Positives = 482/778 (61%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC       D +D+ +GPVIFKR+ PASKQNQ NSE K L+  +H G S  HTS  
Sbjct: 1    MAVEACTTTNLMEDMEDD-EGPVIFKRSNPASKQNQANSEKKKLSLQRHVGQSAVHTSDV 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   NSS QKG    SA T  +                       ANSK   +  
Sbjct: 60   RPANGE---NSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSAGANSKPSASAT 116

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P+    +       +KPLS R     SK  S+ A K 
Sbjct: 117  STAKQQNHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKE 175

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S+DSDE+
Sbjct: 176  GGDSCSIRRPVIEESEDSEDEK-------------PLSRRFTSKSSLGESTSKSYDSDEK 222

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ Q NGS+  +  M     + NKRP     S +QSSLKKPKLS            
Sbjct: 223  KPLAAKVQPNGSASRDSPMNKSASLSNKRPPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 1356 XXAEPKMDDDD-------------------------HVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK +DDD                         +VPI QR+KK  AS +K       
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTATSKPKDEDDDNVPISQRIKKSPASVSKSSAPVKK 342

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 402

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFAVM DTDY  KPRF ENF +DW+++LG+NH I+  E C
Sbjct: 403  KMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDC 462

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+EK+KKKQM+T               KYMWAIVDGVKEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPKMGKLKKRIRP DITINIGK+APIPECPI GERWKEV++DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            IN KEFKYVFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDFT +KD  K+QIAV
Sbjct: 583  INQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV       L+FDFLGKDSIRY N V+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQV 702

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 703  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760


>dbj|BAK32960.1| topoisomerase I [Ophiorrhiza pseudofasciculata]
          Length = 925

 Score =  735 bits (1898), Expect = 0.0
 Identities = 425/778 (54%), Positives = 482/778 (61%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC       D +D+  GPVIFKR+KPA KQNQ NSE K L+  K DG S  HTS  
Sbjct: 1    MAVEACTT-NLMEDMEDDG-GPVIFKRSKPAPKQNQANSEKKKLSLQKQDGQSAVHTSDV 58

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   +SS QKG    SA T  +                       ANSK   +  
Sbjct: 59   RPANGE---SSSAQKGRIQPSAKTPPVKSPLSSPKASNSSAKASPITSPGANSKPSASAT 115

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P+    +       +KPLS R     SK  S+ A K 
Sbjct: 116  STAKQQNHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLSARTFGCSSKGKSNHANKE 174

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S+DSDE+
Sbjct: 175  GGDSCSIRRPVIEESEDSEDEK-------------PLSCRFTSKSSLGESTSKSYDSDEK 221

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ QQNGS+  +  M     + NKRP   A S +QSS+KKPKLS            
Sbjct: 222  KPLAAKVQQNGSASRDGPMNKSASLSNKRPPGEAKSLNQSSVKKPKLSSPITSISNKQAA 281

Query: 1356 XXAEPKM-------------------------DDDDHVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK                          DDDD+VPI QR+KK  AS +K       
Sbjct: 282  VKPEPKAEDDDDNIPLSQRGKKSQSATSKPKDDDDDNVPISQRIKKSPASVSKSSVPVKK 341

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV
Sbjct: 342  ASTVVSSSLKKVNKNSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 401

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFAVM DTDY  KP F ENF +DW++ILG+NH+I+  E C
Sbjct: 402  KMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPCFKENFFSDWKKILGKNHMIQNLEDC 461

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+EK+KKKQM+T               KYMWAIVDGVKEKVGNFRVEPPGL
Sbjct: 462  DFGPIYEWHQQEKEKKKQMTTEEKKALKEEKLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 521

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPKMGKLKKRIRP DITINIGK+APIPECPI GERWKEV++ NTVTWLA+WNDP
Sbjct: 522  FRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNGNTVTWLAYWNDP 581

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            IN KEFKYVFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDFT +KD  K+QIAV
Sbjct: 582  INQKEFKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 641

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV       L+FDFLGKDSIRY N V+V
Sbjct: 642  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVQV 701

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 702  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 759


>dbj|BAG31377.1| topoisomerase I [Catharanthus roseus]
          Length = 910

 Score =  733 bits (1893), Expect = 0.0
 Identities = 417/763 (54%), Positives = 471/763 (61%), Gaps = 42/763 (5%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC  P    D D E D P++FKRN  ASKQ+Q NSE + ++S K DG S R    +
Sbjct: 1    MAVEACPTPNLRDDMD-EDDEPIVFKRNNSASKQSQTNSETRKVSSQKRDGQSVRQIYDS 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSIANSKLPPAGNDKSKRSMGESSKVSDVEKKRL-- 1810
               +G+   +SS QKG  V  +  S + +    P       +S   S KVS    K+   
Sbjct: 60   RPANGE---SSSGQKGRMVPPSKPSQVKSPLSSPPSKPSQVKSPLSSPKVSTSSAKKSPV 116

Query: 1809 ------SKPSVDPGAXXXXXXXDK------------------------------PLSIRL 1738
                  SKPS             K                              PLS+R 
Sbjct: 117  SSLPANSKPSTSGSFKVKPFNQHKSATVIKEEKSSPLRLASAIINDSEDSDDGKPLSLRH 176

Query: 1737 STALSKSNSSPAPKRLKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXX 1558
            S + SK N++   K    P    S                  E PLSS+F          
Sbjct: 177  SASSSKGNTNQVSKEGSKPENEDS----------------DDEKPLSSRFPLKSGVGEST 220

Query: 1557 XXSFDSDEEKPLASRFQQNGSSKSNEMMGL--KVLNKRPSSYANSSDQSSLKKPKLSDGX 1384
              ++DSD++KPLA + Q NGS+  +        + NKRP     SS+Q S+KKPKLS   
Sbjct: 221  SKAYDSDDDKPLAKKLQHNGSAMRDGQPNKYSNMSNKRPPGDIKSSNQLSVKKPKLSSVT 280

Query: 1383 XXXXXXXXXXXAEPKM--DDDDHVPIGQRMKKPVASDNKLQXXXXXXXXXXXXXXXXXXX 1210
                        EPK   DDDDH+PI QR+KK   S++K                     
Sbjct: 281  APTNKKQASVKPEPKAEDDDDDHLPISQRIKKSPTSESK-SSSIKKTTKVVSSSVKKVNK 339

Query: 1209 XXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGVKMLYNGQPVDLTPE 1030
                     KYSKS+KVPP SGEG+KW  L HNGVIFPPPYKPHG+KMLY G+PVDLTPE
Sbjct: 340  KSKKVMKNSKYSKSSKVPPSSGEGKKWNKLEHNGVIFPPPYKPHGIKMLYKGKPVDLTPE 399

Query: 1029 QEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELCDFTAIYEWHQKEKD 850
            QEEVATMFAVM DTDY  KPRF ENF  DW++ILG+NHVI+  E CDF+ IYEWHQ EK+
Sbjct: 400  QEEVATMFAVMLDTDYMNKPRFKENFFGDWKKILGKNHVIQNLENCDFSPIYEWHQSEKE 459

Query: 849  KKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLK 670
            KKKQM+T               KYMWA VDG KEKVGNFRVEPPGLFRGRGEHPKMGKLK
Sbjct: 460  KKKQMTTEEKKALKEEKLKQEEKYMWAWVDGKKEKVGNFRVEPPGLFRGRGEHPKMGKLK 519

Query: 669  KRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAAS 490
            KRIRP DITINIGK+APIPECP+ GERWKEV+HDNTVTWLAFWNDPINPKEFKYVFLAAS
Sbjct: 520  KRIRPCDITINIGKDAPIPECPVPGERWKEVRHDNTVTWLAFWNDPINPKEFKYVFLAAS 579

Query: 489  SSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFTSKDATKRQIAVATYLIDKLALRAGNE 310
            S+LKG SDKEKYEKARLLKDYI  IRA YTKDF SKD TK+QIAVATYLIDKLALRAGNE
Sbjct: 580  STLKGLSDKEKYEKARLLKDYIQGIRAAYTKDFASKDPTKKQIAVATYLIDKLALRAGNE 639

Query: 309  KDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEVEPPVYKAIGQFRSXX 130
            KDDDEADTVGCCTLKVENV       L+FDFLGKDSIRY N VEVE  V+KAI QFRS  
Sbjct: 640  KDDDEADTVGCCTLKVENVEPVPPNILKFDFLGKDSIRYQNEVEVEAAVFKAIQQFRSGK 699

Query: 129  XXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
                      DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 700  EGSSDLFDLLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 742


>ref|XP_006474977.1| PREDICTED: DNA topoisomerase 1-like isoform X1 [Citrus sinensis]
            gi|568842074|ref|XP_006474978.1| PREDICTED: DNA
            topoisomerase 1-like isoform X2 [Citrus sinensis]
            gi|568842076|ref|XP_006474979.1| PREDICTED: DNA
            topoisomerase 1-like isoform X3 [Citrus sinensis]
            gi|568842078|ref|XP_006474980.1| PREDICTED: DNA
            topoisomerase 1-like isoform X4 [Citrus sinensis]
          Length = 902

 Score =  733 bits (1891), Expect = 0.0
 Identities = 417/747 (55%), Positives = 472/747 (63%), Gaps = 26/747 (3%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGS-------- 2008
            MAV+A  KP    D DD+ DGP +FKRN  AS+QN  N E+K  +S   +G         
Sbjct: 1    MAVEASSKPSRVYDFDDDEDGPAVFKRNTAASRQNLANPEVKRPSSSTANGQNSNAPKDK 60

Query: 2007 ----------------SQRHTSGAPSPSGQKTQNSSTQKGNAVSSANTSSIANSKLPPAG 1876
                            SQ+ T+ +   S  K+   S  K + V S   S +ANSK     
Sbjct: 61   TTVSSSKVLPVKSPPPSQKATTSSAKASPSKSPMRSPVK-SPVRSPVKSPVANSKESSPL 119

Query: 1875 NDKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPK 1696
            +D+ K+S   ++    V KK   K      +       DKPLS RL       N      
Sbjct: 120  DDRLKQSPQHNALA--VVKKEEIKDGNGLKSDDNDSEDDKPLSARLKGNSKNVNQGIGAS 177

Query: 1695 RLKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEEKPLAS 1516
            +  + I   +V                  +PLSS+F              DSDE+KPLAS
Sbjct: 178  KADAAISEVNVKTDPEDSDDE--------VPLSSRF-PKSNAGTSGAKPIDSDEKKPLAS 228

Query: 1515 RFQQNGS-SKSNEMMGLKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXXXXAEPK 1339
            + QQNGS S+  +     V  KRP   A+SS  SS KKPK+SD              E K
Sbjct: 229  KVQQNGSTSRETQQKSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKK 288

Query: 1338 MDDDDHVPIGQRMKKPVASDNKLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXKYSKSTKV 1159
             DDDDH+PI QRMK    S  K                              +YSKSTK+
Sbjct: 289  ADDDDHIPISQRMKNSAPSVKKSVTNTAKATKSVSSSSNKINKKTKKVIKNSQYSKSTKM 348

Query: 1158 PPGSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDY 982
             PGSG+GQK WTTLVHNGVIFPPPY PHGVKMLY G+ V+LTPEQEEVATMFAVM DTDY
Sbjct: 349  LPGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDY 408

Query: 981  ATKPRFIENFMNDWRQILGRNHVIKKFELCDFTAIYEWHQKEKDKKKQMSTXXXXXXXXX 802
              KP+F ENF NDWR++LG+NHVI+  E CDF  IY+WHQ++K+KKKQMS+         
Sbjct: 409  MQKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEE 468

Query: 801  XXXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKNA 622
                  KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+PSDITINIGK+ 
Sbjct: 469  KLKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDV 528

Query: 621  PIPECPISGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 442
            PIPECPI GE WKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR
Sbjct: 529  PIPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR 588

Query: 441  LLKDYIHNIRANYTKDFTSKDATKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 262
             LKDYIH+IRA YTKDF S+D T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV
Sbjct: 589  KLKDYIHSIRAAYTKDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 648

Query: 261  ENVSLGDQYKLQFDFLGKDSIRYFNTVEVEPPVYKAIGQFRSXXXXXXXXXXXXDTNKLN 82
             NV      KL+FDFLGKDSI+Y NTVEVE PVYKAIGQF++            DT KLN
Sbjct: 649  GNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLN 708

Query: 81   AHLKELMPGLTAKVFRTYNASITLDDM 1
            AHLKELMPGLTAKVFRTYNASITLD M
Sbjct: 709  AHLKELMPGLTAKVFRTYNASITLDGM 735


>dbj|BAG31374.1| topoisomerase I [Ophiorrhiza liukiuensis]
          Length = 926

 Score =  732 bits (1890), Expect = 0.0
 Identities = 420/778 (53%), Positives = 481/778 (61%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC  P    D +D+ +GPVIFKR+ PASKQNQ NSE K L+  KH G S  HTS  
Sbjct: 1    MAVEACTTPNLMEDMEDD-EGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDV 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   +SS QKG    SA T  +                       ANSKL  +  
Sbjct: 60   RPANGE---SSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASAT 116

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P+    +       +KPL  R S   SK  S+ A K 
Sbjct: 117  STAKQQNHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKE 175

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S+DSDE+
Sbjct: 176  GGDSCSIRRPVIEESEDSEDEK-------------PLSRRFPSKSSLGESTSKSYDSDEK 222

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ QQNGS+  +  M     +LNKR      S +QSSLKK KLS            
Sbjct: 223  KPLATKVQQNGSASRDGPMNKSASLLNKRAPGEVKSLNQSSLKKAKLSSPITSISNKQAA 282

Query: 1356 XXAEPKMDDDD-------------------------HVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK +DDD                         + PI QR+KK  AS +K       
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKK 342

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGV+F PPYKPHGV
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGV 402

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFAVM DTDY TKPRF ENF +DW+++LG+NH ++  E C
Sbjct: 403  KMLYKXQPLTLTPEQEEVATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDC 462

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+EK+K+KQM+T               KYMWAIVDGVKEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKRKQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPKMGKLKKRIRP DITINIGK+APIPECPI GERWKEV++DNTVTWLAFWNDP
Sbjct: 523  FRGRGEHPKMGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAFWNDP 582

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            IN KE KYVFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDFT +KD  K+QIAV
Sbjct: 583  INQKECKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV       L+ DF+GKDSIRY N V+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 703  EPAVFKAIQQFRSGKEGCADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760


>ref|XP_006452480.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|557555706|gb|ESR65720.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 824

 Score =  730 bits (1884), Expect = 0.0
 Identities = 414/746 (55%), Positives = 474/746 (63%), Gaps = 25/746 (3%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDG--------- 2011
            MAV+A  KP    D DD+ DGP +FKRN  AS+QN  N E+K  +S   +G         
Sbjct: 1    MAVEASSKPSRVYDFDDDEDGPAVFKRNTAASRQNLANPEVKRPSSSTANGQNSNAPKDK 60

Query: 2010 ---SSQRHTSGAPSPSGQKTQNSSTQKG-----------NAVSSANTSSIANSKLPPAGN 1873
               SS +       P  QK   SS +             + V S   S +ANSK     +
Sbjct: 61   TTVSSSKVLPVKSPPPSQKATTSSAKASPLKSPMRSPVKSPVRSPVKSPVANSKESSPLD 120

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
            D+ K+ + + + ++ V+K+ + K      +       DKPLS RL       N      +
Sbjct: 121  DRLKQ-LPQHNALAVVKKEEI-KDGNGLKSDDNDSEDDKPLSARLKGNTKNVNQGIGASK 178

Query: 1692 LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEEKPLASR 1513
              + I   +V                  +PLSS+F              DSDE+KPLAS+
Sbjct: 179  ADAAISEVNVKTDPEDSDDE--------VPLSSRF-PKSNAGTSGAKPIDSDEKKPLASK 229

Query: 1512 FQQNGS-SKSNEMMGLKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXXXXAEPKM 1336
             QQNGS S+  +     V  KRP   A+SS  SS KKPK+SD              E K 
Sbjct: 230  VQQNGSTSRETQQKSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKKA 289

Query: 1335 DDDDHVPIGQRMKKPVASDNKLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVP 1156
            DDDDH+PI QRMK    S  K                              +YSKSTK+ 
Sbjct: 290  DDDDHIPISQRMKNSAPSVKKSVTNTAKATKSVSSSSKKINKKTKKVIKNSQYSKSTKML 349

Query: 1155 PGSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYA 979
            PGSG+GQK WTTLVHNGVIFPPPY PHGVKMLY G+ V+LTPEQEEVATMFAVM DTDY 
Sbjct: 350  PGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYM 409

Query: 978  TKPRFIENFMNDWRQILGRNHVIKKFELCDFTAIYEWHQKEKDKKKQMSTXXXXXXXXXX 799
             KP+F ENF NDWR++LG+NHVI+  E CDF  IY+WHQ++K+KKKQMS+          
Sbjct: 410  QKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEK 469

Query: 798  XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKNAP 619
                 KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+PSDITINIGK+ P
Sbjct: 470  LKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVP 529

Query: 618  IPECPISGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARL 439
            IPECPI GE WKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSD+EKYEKAR 
Sbjct: 530  IPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDREKYEKARK 589

Query: 438  LKDYIHNIRANYTKDFTSKDATKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 259
            LKDYIH+IRA YTKDF S+D T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 
Sbjct: 590  LKDYIHSIRAAYTKDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVG 649

Query: 258  NVSLGDQYKLQFDFLGKDSIRYFNTVEVEPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNA 79
            NV      KL+FDFLGKDSI+Y NTVEVE PVYKAIGQF++            DT KLNA
Sbjct: 650  NVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNA 709

Query: 78   HLKELMPGLTAKVFRTYNASITLDDM 1
            HLKELMPGLTAKVFRTYNASITLD M
Sbjct: 710  HLKELMPGLTAKVFRTYNASITLDGM 735


>ref|XP_006452479.1| hypothetical protein CICLE_v10007398mg [Citrus clementina]
            gi|567920950|ref|XP_006452481.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555705|gb|ESR65719.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
            gi|557555707|gb|ESR65721.1| hypothetical protein
            CICLE_v10007398mg [Citrus clementina]
          Length = 902

 Score =  730 bits (1884), Expect = 0.0
 Identities = 414/746 (55%), Positives = 474/746 (63%), Gaps = 25/746 (3%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDG--------- 2011
            MAV+A  KP    D DD+ DGP +FKRN  AS+QN  N E+K  +S   +G         
Sbjct: 1    MAVEASSKPSRVYDFDDDEDGPAVFKRNTAASRQNLANPEVKRPSSSTANGQNSNAPKDK 60

Query: 2010 ---SSQRHTSGAPSPSGQKTQNSSTQKG-----------NAVSSANTSSIANSKLPPAGN 1873
               SS +       P  QK   SS +             + V S   S +ANSK     +
Sbjct: 61   TTVSSSKVLPVKSPPPSQKATTSSAKASPLKSPMRSPVKSPVRSPVKSPVANSKESSPLD 120

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
            D+ K+ + + + ++ V+K+ + K      +       DKPLS RL       N      +
Sbjct: 121  DRLKQ-LPQHNALAVVKKEEI-KDGNGLKSDDNDSEDDKPLSARLKGNTKNVNQGIGASK 178

Query: 1692 LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEEKPLASR 1513
              + I   +V                  +PLSS+F              DSDE+KPLAS+
Sbjct: 179  ADAAISEVNVKTDPEDSDDE--------VPLSSRF-PKSNAGTSGAKPIDSDEKKPLASK 229

Query: 1512 FQQNGS-SKSNEMMGLKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXXXXAEPKM 1336
             QQNGS S+  +     V  KRP   A+SS  SS KKPK+SD              E K 
Sbjct: 230  VQQNGSTSRETQQKSSSVPVKRPLQKASSSGASSAKKPKVSDTSKEVKVKQVTVKVEKKA 289

Query: 1335 DDDDHVPIGQRMKKPVASDNKLQXXXXXXXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVP 1156
            DDDDH+PI QRMK    S  K                              +YSKSTK+ 
Sbjct: 290  DDDDHIPISQRMKNSAPSVKKSVTNTAKATKSVSSSSKKINKKTKKVIKNSQYSKSTKML 349

Query: 1155 PGSGEGQK-WTTLVHNGVIFPPPYKPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYA 979
            PGSG+GQK WTTLVHNGVIFPPPY PHGVKMLY G+ V+LTPEQEEVATMFAVM DTDY 
Sbjct: 350  PGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYM 409

Query: 978  TKPRFIENFMNDWRQILGRNHVIKKFELCDFTAIYEWHQKEKDKKKQMSTXXXXXXXXXX 799
             KP+F ENF NDWR++LG+NHVI+  E CDF  IY+WHQ++K+KKKQMS+          
Sbjct: 410  QKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWHQEQKEKKKQMSSEEKKALKEEK 469

Query: 798  XXXXXKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKNAP 619
                 KYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRI+PSDITINIGK+ P
Sbjct: 470  LKQEEKYMWAIVDGVKEKVGNFRVEPPGLFRGRGEHPKMGKLKKRIQPSDITINIGKDVP 529

Query: 618  IPECPISGERWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARL 439
            IPECPI GE WKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSD+EKYEKAR 
Sbjct: 530  IPECPIPGESWKEVKHDNTVTWLAFWNDPINPKEFKYVFLAASSSLKGQSDREKYEKARK 589

Query: 438  LKDYIHNIRANYTKDFTSKDATKRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVE 259
            LKDYIH+IRA YTKDF S+D T+RQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV 
Sbjct: 590  LKDYIHSIRAAYTKDFVSRDGTRRQIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVG 649

Query: 258  NVSLGDQYKLQFDFLGKDSIRYFNTVEVEPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNA 79
            NV      KL+FDFLGKDSI+Y NTVEVE PVYKAIGQF++            DT KLNA
Sbjct: 650  NVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNA 709

Query: 78   HLKELMPGLTAKVFRTYNASITLDDM 1
            HLKELMPGLTAKVFRTYNASITLD M
Sbjct: 710  HLKELMPGLTAKVFRTYNASITLDGM 735


>dbj|BAG31373.1| topoisomerase I [Ophiorrhiza pumila]
          Length = 926

 Score =  730 bits (1884), Expect = 0.0
 Identities = 418/778 (53%), Positives = 479/778 (61%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC  P    D +D+ +GPVIFKR+ PASKQNQ NSE K L+  KH G S  HTS  
Sbjct: 1    MAVEACTTPNLMEDMEDD-EGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDV 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   +SS QKG    SA T  +                       ANSKL  +  
Sbjct: 60   RPANGE---SSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASAT 116

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P+    +       +KPL  R S   SK  S+ A K 
Sbjct: 117  STAKQQNHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKE 175

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S DSDE+
Sbjct: 176  GGDSCSIRRPVIEESEDSEDEK-------------PLSRRFPSKSSLGESTSKSHDSDEK 222

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ QQNGS+  +  M     + NKR      S +QSSLKKPKLS            
Sbjct: 223  KPLAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSTITSISNKQAA 282

Query: 1356 XXAEPKMDDDD-------------------------HVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK +DDD                         + PI QR+KK  AS +K       
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKK 342

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGV+FPPPYKPHGV
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGV 402

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFA M DTDY  KPRF ENF +DW++ILG+NH I+  E C
Sbjct: 403  KMLYKRQPLTLTPEQEEVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDC 462

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+EK+KKKQM+T               KYMWAIVDGVKEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKKKQMTTEEKKALKEERLQLEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPK+GKLKKRIRP DITINIGK+APIPECPI GERWKEV++DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            +N KE KYVFLAASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDFT +KD  K+Q+AV
Sbjct: 583  VNLKECKYVFLAASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQVAV 642

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV       L+ DF+GKDSIRY N V+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 703  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760


>dbj|BAK32959.1| topoisomerase I [Ophiorrhiza plumbea]
          Length = 920

 Score =  729 bits (1883), Expect = 0.0
 Identities = 418/778 (53%), Positives = 478/778 (61%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC  P    D +D+ +GPVIFKR+ PASKQNQ NSE K L+  KH G S  HTS  
Sbjct: 1    MAVEACTTPNLMEDMEDD-EGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDV 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   +SS QKG    SA T  +                       ANSKL  +  
Sbjct: 60   RPANGE---SSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASAT 116

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P+    +       +KPL  R S   SK  S+ A K 
Sbjct: 117  STAKQQNHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKE 175

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S+DSDE+
Sbjct: 176  GGDSCSIRRPVIEESEDSEDEK-------------PLSRRFPSKSSLGESTSKSYDSDEK 222

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ Q NGS+  +  M     + NKR      S +QSSLKKPKLS            
Sbjct: 223  KPLAAKVQPNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 1356 XXAEPKMDDDD-------------------------HVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK +DDD                         + PI QR+KK  AS +K       
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKK 342

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 402

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFAVM DTDY  KPRF ENF +DW+++LG+NH I+  E C
Sbjct: 403  KMLYKRQPITLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDC 462

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+EK+KKKQM+T               KYMW IVDGVKEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKKKQMTTEEKKALKEERLQQEEKYMWVIVDGVKEKVGNFRVEPPGL 522

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPK+GKLKKRIRP DITINIGK+APIPECPI GERWKEV++DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            IN KE KYVFL ASS+LKGQSDKEKYEKARLLKDYIH IRA YTKDFT +KD  K+QIAV
Sbjct: 583  INQKERKYVFLGASSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV       L+ DF+GKDSIRY N V+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 703  EPAVFKAIQQFRSGKEGSADLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760


>ref|XP_002300344.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222847602|gb|EEE85149.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 877

 Score =  729 bits (1882), Expect = 0.0
 Identities = 413/720 (57%), Positives = 470/720 (65%), Gaps = 13/720 (1%)
 Frame = -1

Query: 2124 DCDDESDGPVIFKRN-KPASKQNQLNSEIKNLTSPKHDGSSQ-----RHTSGAPSPSGQK 1963
            D DD+ DGP++FKR     SKQNQLN E K  +S   + + Q     +  S  PS +   
Sbjct: 16   DDDDDDDGPIVFKRGGNSTSKQNQLNPEAKKPSSSSQNSNGQSLNLQKGKSPIPSSNASP 75

Query: 1962 TQNSSTQKGNAVSSANTSSIAN----SKLPPAGNDKSKRSMGESSKVSDVEKKRLSKPSV 1795
             ++S+     + SSA  S + +    ++   + ND+ K++   S +V     K  +K  V
Sbjct: 76   MKSSTGSPKASASSAKASPLKSPLTYTRALTSSNDQLKQA---SKQVVSNAVKEETKSIV 132

Query: 1794 DPGAXXXXXXXDKPLSIRLSTALSKSNSS-PAPKRLKSPIPSPSVAXXXXXXXXXXXXXX 1618
            D          DKPLS R+  + +  N    AP  +K   PS                  
Sbjct: 133  DD----EDSEDDKPLSSRIKGSTNNVNKGVTAPAHVKDE-PSDD---------------- 171

Query: 1617 XXEIPLSSKFRXXXXXXXXXXXSFDSDEEKPLASRFQQNGSSKSNEMMGLKVL-NKRPSS 1441
              E+PLSS+F            S  S E +P  S+ Q NGS+K+++     V+  KRP  
Sbjct: 172  -DEVPLSSRFAMKSNAGTSSSKSIRSSEIRPFPSKSQLNGSTKNDKQQKSSVVPTKRPMD 230

Query: 1440 YANSSDQSSLKKPKLSDGXXXXXXXXXXXXAEPKMDDDDHVPIGQRMKKPVASDNKLQXX 1261
                S+ SS KKPKL D              E K DDDDH+ I QRMKK  +S NK    
Sbjct: 231  NKVPSNHSSAKKPKLLDACTTTKVKQVTVKVEQKADDDDHLTISQRMKKADSSANKSSFA 290

Query: 1260 XXXXXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQK-WTTLVHNGVIFPPPYK 1084
                                      KYSKSTKV PGS +GQK WTTLVHNGVIFPPPYK
Sbjct: 291  KKKVTKVVSSSLKKTTQKNKKQMKNSKYSKSTKVQPGSSDGQKKWTTLVHNGVIFPPPYK 350

Query: 1083 PHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKK 904
            PHGVK+LY G+P+DLTPEQEEVATMFAVMKDTDY  KP+F +NF NDWR++LG+NHVI+K
Sbjct: 351  PHGVKILYKGKPIDLTPEQEEVATMFAVMKDTDYVQKPQFRQNFWNDWRKLLGKNHVIQK 410

Query: 903  FELCDFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVE 724
             + CDF  IYEWHQ+EK+KKKQMST               KYMWAIV+GVKEKVGNFRVE
Sbjct: 411  LDDCDFNPIYEWHQQEKEKKKQMSTEEKKVLKEEKLKQEEKYMWAIVNGVKEKVGNFRVE 470

Query: 723  PPGLFRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAF 544
            PPGLFRGRGEHPKMGKLK RIRPSDITINIGK+APIPECPI GERWKEVKHDNTVTWLAF
Sbjct: 471  PPGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPECPIPGERWKEVKHDNTVTWLAF 530

Query: 543  WNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFTSKDATKRQ 364
            WNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIHNIRA YTKDF SKD TKRQ
Sbjct: 531  WNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIRAAYTKDFASKDITKRQ 590

Query: 363  IAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNT 184
            IAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV      KL+FDFLGKDSIRY NT
Sbjct: 591  IAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLGKDSIRYENT 650

Query: 183  VEVEPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDD 4
            VEVE PVYKAIG F+             DT+KLNAHLKELMPGLTAKVFRTYNASITLD+
Sbjct: 651  VEVELPVYKAIGHFQVAKKQTDDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLDE 710


>dbj|BAK32963.1| topoisomerase I [Ophiorrhiza sp. 35]
          Length = 920

 Score =  724 bits (1868), Expect = 0.0
 Identities = 415/778 (53%), Positives = 477/778 (61%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC       D +D+ +GPVIFKR+ PASKQNQ NSE K L+  KH G S  HTS  
Sbjct: 1    MAVEACTTTNLMEDMEDD-EGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDV 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   +SS QKG    SA T  +                       ANSKL  +  
Sbjct: 60   RPANGE---SSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASAT 116

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P     +       +KPL  R S   SK  S+ A K 
Sbjct: 117  STAKQQNHHKSSAAFIEPKP-SVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKE 175

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S+DSDE+
Sbjct: 176  GGDSCSIRRPVVEESEDSEDEK-------------PLSRRFPSKSSLGESTSKSYDSDEK 222

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ QQNGS+  +  M     + NKR      S +QSSLKKPKLS            
Sbjct: 223  KPLAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 1356 XXAEPKMDDDD-------------------------HVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK +DDD                         + PI QR+KK  AS +K       
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKK 342

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 402

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFAVM DTDY  KPRF ENF +DW+++LG+NH I+  E C
Sbjct: 403  KMLYKRQPLTLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKMLGKNHTIQNLEDC 462

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+E++KKKQM+T               KYMWAIVDGVKEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEREKKKQMTTEEKKALKDERLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPK+GKLKKRI P DITINIGK+APIPECPI GERWKEV++DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKVGKLKKRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            +N KE KYVFLA SS+LKGQSDKEKYEKARLLKDYIH IRA YTKDFT +KD  K+QIAV
Sbjct: 583  VNLKECKYVFLAPSSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTL+VENV       L+ DF+GKDSIRY N V+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLRVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 703  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760


>dbj|BAK32956.1| topoisomerase I [Ophiorrhiza fucosa]
          Length = 926

 Score =  723 bits (1867), Expect = 0.0
 Identities = 415/778 (53%), Positives = 476/778 (61%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC       D +D+ +GPVIFKR+ PASKQNQ NSE K L+  KH G S  HTS  
Sbjct: 1    MAVEACTTTNLMEDMEDD-EGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDV 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   +SS QKG    SA T  +                       ANSKL  +  
Sbjct: 60   RPANGE---SSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASAT 116

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P     +       +KPL  R S   SK  S+ A K 
Sbjct: 117  STAKQQNHHKSSAAFIEPKP-SVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKE 175

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S+DSDE+
Sbjct: 176  GGDSCSIRRPVVEESEDSEDEK-------------PLSRRFPSKSSLGESTSKSYDSDEK 222

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ QQNGS+  +  M     + NKR      S +QSSLKKPKLS            
Sbjct: 223  KPLAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 1356 XXAEPKMDDDD-------------------------HVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK +DDD                         + PI QR+KK  AS +K       
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKK 342

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGV+FPPPYKPHGV
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGV 402

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFA M DTDY  KPRF ENF +DW++ILG+NH I+  E C
Sbjct: 403  KMLYKRQPLTLTPEQEEVATMFAAMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDC 462

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+E++KKKQM+T               KYMWAIVDGVKEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEREKKKQMTTEEKKALKDERLQLEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPK+GKLKKRI P DITINIGK+APIPECPI GERWKEV++DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKVGKLKKRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            +N KE KYVFLA SS+LKGQSDKEKYEKARLLKDYIH IRA YTKDFT +KD  K+QIAV
Sbjct: 583  VNLKECKYVFLAPSSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV       L+ DF+GKDSIRY N V+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 703  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760


>dbj|BAK32961.1| topoisomerase I [Ophiorrhiza ridleyana]
          Length = 926

 Score =  719 bits (1855), Expect = 0.0
 Identities = 413/778 (53%), Positives = 474/778 (60%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC       D +D+ +GPVIFKR+ P SKQNQ N+E K L+  KH G S  HTS  
Sbjct: 1    MAVEACTTTNLMEDMEDD-EGPVIFKRSNPTSKQNQANAEKKKLSLQKHVGQSAVHTSDV 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   +SS QKG    SA T  +                       ANSKL  +  
Sbjct: 60   RPANGE---SSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASAT 116

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P+    +       +KPL  R S   S   S+ A K 
Sbjct: 117  STAKQQNHHKSSAAFIEPKP-SVPAAKANSNSESSDDEKPLIARTSGCSSMGKSNHANKE 175

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S+DSDE+
Sbjct: 176  GGDSCSIRRPVIEESEDSEDEK-------------PLSRRFPSKSSLGESTSKSYDSDEK 222

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ QQNGS+     M     + NKR      S +QSSLKKPKLS            
Sbjct: 223  KPLAAKVQQNGSASPEGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 1356 XXAEPKMDDDD-------------------------HVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK +DDD                         H PI QR+KK   S +K       
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDHAPISQRIKKSPVSVSKSSAPVKK 342

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGV+FPPPYKPHGV
Sbjct: 343  ASTVVSTSLKKVNKKSKKVIRKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFPPPYKPHGV 402

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFAVM DTDY  KPRF ENF +DW++ILG+NH I+  E C
Sbjct: 403  KMLYKRQPLTLTPEQEEVATMFAVMLDTDYMNKPRFKENFFSDWKKILGKNHTIQNLEDC 462

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+EK+KKKQM+T               KYMWAIVDGVKEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKKKQMTTEEKKALKEERLQQEEKYMWAIVDGVKEKVGNFRVEPPGL 522

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPK+GKLKKRIRP DITINIGK+APIPECPI GERWKEV++DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKVGKLKKRIRPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            +N KE KYVFLAASS+LKGQS KEKYEKAR+LKDYIH IRA YTK FT +KD  K+QIAV
Sbjct: 583  VNIKECKYVFLAASSTLKGQSVKEKYEKARVLKDYIHGIRAAYTKGFTNNKDPMKKQIAV 642

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV       L+ DF+GKDSIRY N V+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 703  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760


>ref|XP_002317355.1| DNA topoisomerase family protein [Populus trichocarpa]
            gi|222860420|gb|EEE97967.1| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 860

 Score =  719 bits (1855), Expect = 0.0
 Identities = 410/721 (56%), Positives = 462/721 (64%), Gaps = 16/721 (2%)
 Frame = -1

Query: 2118 DDESDGPVIFKRN-KPASKQNQLNSEIKNLTSPKHDGSSQRHTSGAPSPSGQKTQNSSTQ 1942
            DD+ DGP++FKR     SKQNQ N E K         SS ++++G         Q+ +  
Sbjct: 17   DDDDDGPIVFKRGGNSTSKQNQPNLEAKK------PSSSSQNSNG---------QSLNAH 61

Query: 1941 KGNA-VSSANTSSIANSKLPPAGNDKSKRSMGESSKV-----------SDVEKKRLSKPS 1798
            KG + +SS+N S + +    P G+ K+  S  ++S +           S +  K  +KP 
Sbjct: 62   KGKSPISSSNASPVKS----PIGSPKASASSAKASPMKPPVTYSRVPSSSIAVKEETKPI 117

Query: 1797 VDPGAXXXXXXXDKPLSIRLSTALSKSNSS-PAPKRLKSPIPSPSVAXXXXXXXXXXXXX 1621
            VD          DKPLS R   + + +N     P R+K                      
Sbjct: 118  VDDD----DSEDDKPLSSRFKGSTNNANKGVTVPARVKDEHSDDD--------------- 158

Query: 1620 XXXEIPLSSKFRXXXXXXXXXXXSFDSDEEKPLASRFQQNGSS-KSNEMMGLKVLNKRPS 1444
               E+PLSS+F            +  S E+  L S+ Q NGS+ K  +     V  KRP 
Sbjct: 159  ---EVPLSSRFAAKSNAGSSSCKTISSSEKILLVSKIQLNGSTAKDKQQKSSAVPTKRPM 215

Query: 1443 SYANSSDQSSLKKPKLSDGXXXXXXXXXXXXAEPKMDDDDHVPIGQRMKKPVASDNKLQX 1264
                 S+QS  KKPKLSD              E K DDDDH+ I QRMKK  +S NK   
Sbjct: 216  DNKVPSNQSFAKKPKLSDASTTKQVTVKA---ELKADDDDHLTISQRMKKASSSSNKSLS 272

Query: 1263 XXXXXXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQK-WTTLVHNGVIFPPPY 1087
                                       KYSKSTKV PGS +GQK W TLVHNGVIFPPPY
Sbjct: 273  VKQNVTKVVSFSSKKTTKNNKKQMQNSKYSKSTKVQPGSSDGQKKWKTLVHNGVIFPPPY 332

Query: 1086 KPHGVKMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIK 907
            KPHGVKMLY G+PVDLTPEQEEVATMFAVMKDT+Y  KP+F++NF NDWR +LG+NHVI+
Sbjct: 333  KPHGVKMLYKGKPVDLTPEQEEVATMFAVMKDTEYVQKPQFLQNFWNDWRTLLGKNHVIQ 392

Query: 906  KFELCDFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRV 727
            K E CDF  IYEWHQKEK+KKKQMST                YMWAIV+GVKEKVGNFRV
Sbjct: 393  KLEACDFNPIYEWHQKEKEKKKQMSTEEKKAVREEKLKQEEMYMWAIVNGVKEKVGNFRV 452

Query: 726  EPPGLFRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLA 547
            EPPGLFRGRGEHPKMGKLK RIRPSDITINIGK+APIP+CPI GERWKEVKHDNTVTWLA
Sbjct: 453  EPPGLFRGRGEHPKMGKLKSRIRPSDITINIGKDAPIPKCPIPGERWKEVKHDNTVTWLA 512

Query: 546  FWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFTSKDATKR 367
            FWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKAR LKDYIHNIR  YTKDF SKD TKR
Sbjct: 513  FWNDPINPKEFKYVFLAASSSLKGQSDKEKYEKARKLKDYIHNIRTAYTKDFASKDITKR 572

Query: 366  QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFN 187
            QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKV NV      KL+FDFLGKDSIRY N
Sbjct: 573  QIAVATYLIDKLALRAGNEKDDDEADTVGCCTLKVANVECIPPNKLKFDFLGKDSIRYEN 632

Query: 186  TVEVEPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLD 7
            TVEVE PVYKAI QF+             DT+KLNAHLKELMPGLTAKVFRTYNASITLD
Sbjct: 633  TVEVELPVYKAIRQFQVAKKPTDDLFDSLDTSKLNAHLKELMPGLTAKVFRTYNASITLD 692

Query: 6    D 4
            +
Sbjct: 693  E 693


>dbj|BAK32957.1| topoisomerase I [Ophiorrhiza harrisiana]
          Length = 920

 Score =  716 bits (1848), Expect = 0.0
 Identities = 413/778 (53%), Positives = 476/778 (61%), Gaps = 57/778 (7%)
 Frame = -1

Query: 2163 MAVDACIKPKFPGDCDDESDGPVIFKRNKPASKQNQLNSEIKNLTSPKHDGSSQRHTSGA 1984
            MAV+AC       D +D+ +GPVIFKR+ PASKQNQ NSE K L+  KH G S  HTS  
Sbjct: 1    MAVEACTTTNLMEDMEDD-EGPVIFKRSNPASKQNQANSEKKKLSLQKHVGQSAVHTSDV 59

Query: 1983 PSPSGQKTQNSSTQKGNAVSSANTSSI-----------------------ANSKLPPAGN 1873
               +G+   +SS QKG    SA T  +                       ANSKL  +  
Sbjct: 60   RPANGE---SSSAQKGRIQPSAETPPVKSPLSSPKASNSSAKASPITSPGANSKLSASAT 116

Query: 1872 DKSKRSMGESSKVSDVEKKRLSKPSVDPGAXXXXXXXDKPLSIRLSTALSKSNSSPAPKR 1693
              +K+     S  + +E K  S P     +       +KPL  R S   SK  S+ A K 
Sbjct: 117  STAKQQNHHKSSAAFIEPKP-SVPPAKANSNSESSDDEKPLIARTSGCSSKGKSNHANKE 175

Query: 1692 ------LKSPIPSPSVAXXXXXXXXXXXXXXXXEIPLSSKFRXXXXXXXXXXXSFDSDEE 1531
                  ++ P+   S                    PLS +F            S+DSDE+
Sbjct: 176  GGDSCSIRRPVVEESEDSEDEK-------------PLSRRFPSKSSLGESTSKSYDSDEK 222

Query: 1530 KPLASRFQQNGSSKSNEMMG--LKVLNKRPSSYANSSDQSSLKKPKLSDGXXXXXXXXXX 1357
            KPLA++ QQNGS+  +  M     + NKR      S +QSSLKKPKLS            
Sbjct: 223  KPLAAKVQQNGSASRDGPMNKSASLSNKRAPGEVKSLNQSSLKKPKLSSPITSISNKQAA 282

Query: 1356 XXAEPKMDDDD-------------------------HVPIGQRMKKPVASDNKLQXXXXX 1252
               EPK +DDD                         + PI QR+KK  AS +K       
Sbjct: 283  VKPEPKAEDDDDNIPLSQRGKKSQTAASKPKDEDDDNAPISQRIKKSPASVSKSSAPVKK 342

Query: 1251 XXXXXXXXXXXXXXXXXXXXXXXKYSKSTKVPPGSGEGQKWTTLVHNGVIFPPPYKPHGV 1072
                                    Y+KS+KVPPGSGEGQKWTTLVHNGV+F PPYKPHGV
Sbjct: 343  ASTVVSPSLKKVNKKSKKVIKKTAYTKSSKVPPGSGEGQKWTTLVHNGVMFLPPYKPHGV 402

Query: 1071 KMLYNGQPVDLTPEQEEVATMFAVMKDTDYATKPRFIENFMNDWRQILGRNHVIKKFELC 892
            KMLY  QP+ LTPEQEEVATMFAVM DTDY TKPRF ENF +DW+++LG+NH ++  E C
Sbjct: 403  KMLYKQQPLTLTPEQEEVATMFAVMLDTDYMTKPRFKENFFSDWKKMLGKNHTVQNLEDC 462

Query: 891  DFTAIYEWHQKEKDKKKQMSTXXXXXXXXXXXXXXXKYMWAIVDGVKEKVGNFRVEPPGL 712
            DF  IYEWHQ+EK+K+KQM+T               KYM AIVDGVKEKVGNFRVEPPGL
Sbjct: 463  DFGPIYEWHQQEKEKRKQMTTEEKKALKEERLQQEEKYMRAIVDGVKEKVGNFRVEPPGL 522

Query: 711  FRGRGEHPKMGKLKKRIRPSDITINIGKNAPIPECPISGERWKEVKHDNTVTWLAFWNDP 532
            FRGRGEHPK+GKLKKRI P DITINIGK+APIPECPI GERWKEV++DNTVTWLA+WNDP
Sbjct: 523  FRGRGEHPKVGKLKKRIHPRDITINIGKDAPIPECPIPGERWKEVRNDNTVTWLAYWNDP 582

Query: 531  INPKEFKYVFLAASSSLKGQSDKEKYEKARLLKDYIHNIRANYTKDFT-SKDATKRQIAV 355
            +N KE KYVFLA SS+LKGQSDKEKYEKARLLKDYIH IRA YTKDFT +KD  K+QIAV
Sbjct: 583  VNLKECKYVFLAPSSTLKGQSDKEKYEKARLLKDYIHGIRAAYTKDFTNNKDPMKKQIAV 642

Query: 354  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVSLGDQYKLQFDFLGKDSIRYFNTVEV 175
            ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENV       L+ DF+GKDSIRY N V+V
Sbjct: 643  ATYLIDKLALRAGNEKDDDEADTVGCCTLKVENVEPVPPNILKIDFIGKDSIRYQNEVQV 702

Query: 174  EPPVYKAIGQFRSXXXXXXXXXXXXDTNKLNAHLKELMPGLTAKVFRTYNASITLDDM 1
            EP V+KAI QFRS            DT+KLNAHLKELMPGLTAKVFRTYNASITLDDM
Sbjct: 703  EPAVFKAIQQFRSGKEGSEDLFDRLDTSKLNAHLKELMPGLTAKVFRTYNASITLDDM 760