BLASTX nr result
ID: Cocculus23_contig00003977
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Cocculus23_contig00003977
(1334 letters)
Database: ./nr
38,876,450 sequences; 13,856,398,315 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. g... 242 e-107
sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Sh... 244 e-104
gb|AHF65153.1| stylopine synthase, partial [synthetic construct] 243 e-104
gb|ADB89214.1| stylopine synthase [Papaver somniferum] 243 e-104
gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis] 236 e-102
sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; Alt... 235 e-102
gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum] 233 e-100
sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; ... 230 e-100
sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase;... 225 e-100
gb|ACO90219.1| stylopine synthase [Eschscholzia californica] 230 e-100
dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta] 242 2e-98
sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; ... 225 3e-98
gb|AFB74615.1| cytochrome P450 [Papaver somniferum] 229 1e-97
sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase;... 224 2e-96
dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica] 229 3e-96
dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta] 232 3e-95
gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum] 224 3e-95
dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica] 225 1e-94
dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica] 224 2e-93
gb|AGC29953.1| CYP719A23 [Sinopodophyllum hexandrum] 219 4e-90
>gb|AAU20771.1| (S)-canadine synthase [Thalictrum flavum subsp. glaucum]
Length = 492
Score = 242 bits (617), Expect(2) = e-107
Identities = 126/269 (46%), Positives = 183/269 (68%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG F DD F E M I+D +R++G L + F + +Y+PS K +E +K R+++
Sbjct: 196 FGQTFD-DDKFVESMHFEIDDIIRISGYARLAEAFYYAKYLPSHKKAEREAYLVKCRVED 254
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+SP LS++ P++S YL FLLSQ F+E+++IF +FEL+ VDSTS TT WALA++I
Sbjct: 255 LVSPLLSSNPPTNS---YLYFLLSQRFSEEVIIFCIFELYLLGVDSTSSTTTWALAYLIR 311
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
+ IQ+++ + + LG +V +EDV S+++Y+ AVVKET RM+PIAPLA+PH+ +D
Sbjct: 312 EQAIQEKLYQDTRMTLGDVD-LVKIEDV-SKLKYLQAVVKETMRMKPIAPLAIPHKTAKD 369
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFIP 88
+ L G KV +GT + VNLYA+ H++ +W P +FMPERFL G G ++ K ME+SF+P
Sbjct: 370 TTLMGSKVAKGTRIMVNLYALHHNQNIWTNPYKFMPERFL-QGEDGSASN-KAMEQSFLP 427
Query: 87 FGAGRRSCPAMELAKAEVALTLANLVNSF 1
F AG R C M+L K + A LANLVN+F
Sbjct: 428 FSAGMRICAGMDLGKLQFAFALANLVNAF 456
Score = 176 bits (445), Expect(2) = e-107
Identities = 78/157 (49%), Positives = 117/157 (74%)
Frame = -1
Query: 1325 LLMKLLDQTFFISKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGG 1146
+L+ ++ + S+ +WPTGP + P++GNL+QL G++LH+ LAK+AQ HG +MTVW G
Sbjct: 21 ILIPMVTSSSSFSQMKWPTGPNKLPIIGNLHQLG-GDVLHVALAKLAQVHGSVMTVWIGN 79
Query: 1145 LQPSIVVSDHELAWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQ 966
+P IV+SD + AWEVLV K+SDY +R MP ++KI SA WHT++TS+ G +W+T+RKGLQ
Sbjct: 80 WRPIIVISDIDKAWEVLVNKSSDYGARDMPEITKIASASWHTISTSDAGAFWQTVRKGLQ 139
Query: 965 STTLHPNTISSQTQLQEKDIADLISSLEEEASLNNGV 855
S + P I++Q+Q QE+D+ LI +L +EA+ NN +
Sbjct: 140 SGAMGPLNIAAQSQFQERDMKRLIQALRDEAAQNNNI 176
>sp|B1NF19.1|C719D_ARGME RecName: Full=(S)-stylopine synthase; Short=STS; AltName:
Full=Cytochrome P450 719A13 gi|148841092|gb|ABR14721.1|
stylopine synthase [Argemone mexicana]
Length = 504
Score = 244 bits (622), Expect(2) = e-104
Identities = 122/270 (45%), Positives = 181/270 (67%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
+G +F +D+ + E M IE+ +R++G L + F + +Y+PS K +E+ QR++
Sbjct: 207 YGQDFDNDE-YVEEMHHTIEELIRVSGYARLAEAFYYAKYLPSHKKAVREVLQANQRVQN 265
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P LS + P+ N YL FL SQ + ++++IF +FE + VDSTS TTAWALA++I
Sbjct: 266 LVRPLLSLNSPT---NTYLHFLRSQNYEDEVIIFAIFEAYLLGVDSTSSTTAWALAYLIR 322
Query: 447 HENIQQRVLKQVKNRLGGT-RRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
N+Q+++ +++KN R+MV ED+ ++++Y+ AVVKET RM+PIAPLA+PH+A R
Sbjct: 323 EPNVQEKLYEELKNFTNDNDRKMVKFEDL-NKLQYLQAVVKETMRMKPIAPLAIPHKACR 381
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
++ L G KV +GT V VN+YA+ H++ VWKEP +F PERFL DG D K ME+S +
Sbjct: 382 ETSLMGRKVNQGTRVMVNIYALHHNQNVWKEPYKFNPERFLQKNQ--DGVDGKAMEQSLL 439
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C MEL K + + LANLVN+F
Sbjct: 440 PFSAGMRICAGMELGKLQFSFALANLVNAF 469
Score = 163 bits (412), Expect(2) = e-104
Identities = 78/165 (47%), Positives = 111/165 (67%), Gaps = 8/165 (4%)
Frame = -1
Query: 1325 LLMKLLDQTFFI--------SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGR 1170
+L+ LL F I SK WPTGP P++GN+ L G LH+ L +A+ +G
Sbjct: 24 ILLSLLFTIFIILRRNKSSSSKMVWPTGPKTLPIIGNMNILG-GTALHVVLHNLAKTYGN 82
Query: 1169 IMTVWFGGLQPSIVVSDHELAWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYW 990
+MT+W G +P IVVSD + AWEVLV K+SDYS+R MP ++K+ +ADW T+++S+ GP+W
Sbjct: 83 VMTIWIGSWRPVIVVSDIDRAWEVLVNKSSDYSARDMPEITKLATADWKTISSSDSGPFW 142
Query: 989 ETLRKGLQSTTLHPNTISSQTQLQEKDIADLISSLEEEASLNNGV 855
LRKGLQ+ L P +SSQ++ QE+DI I +L+EEA +NNG+
Sbjct: 143 TNLRKGLQNVALSPQNLSSQSKFQERDIIKTIQNLKEEAKMNNGI 187
>gb|AHF65153.1| stylopine synthase, partial [synthetic construct]
Length = 511
Score = 243 bits (621), Expect(2) = e-104
Identities = 125/270 (46%), Positives = 185/270 (68%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG +F DD + + M AIE+ +R++G L + F + +Y+PS K +++E QR+K+
Sbjct: 212 FGQDFD-DDKYVDDMHHAIEELIRVSGYAQLAEAFYYAKYLPSHKKAVRDVEEANQRVKK 270
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P+LS + P+ N YL FL SQ + E+++IF +FE + VDSTS TTAWALAF+I
Sbjct: 271 LVRPFLSLNPPT---NTYLHFLNSQKYDEEVIIFAIFEAYLLGVDSTSLTTAWALAFLIR 327
Query: 447 HENIQQRVLKQVKNRLGGTR-RMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
+Q ++ +++KN +V VED+ ++++Y+ AV+KET RM+PIAPLA+PH+A R
Sbjct: 328 EPVVQDKLYQELKNLTAKNDCEIVKVEDL-NKLQYLQAVLKETMRMKPIAPLAIPHKACR 386
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
D+ L+G K+ +GT V VN+YA+ H+EKVWKEP +FMPERFL + +G K ME+S +
Sbjct: 387 DTSLKGNKIDQGTQVMVNIYALHHNEKVWKEPFKFMPERFLQTQDVVNG---KGMEQSLL 443
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C MEL K + + +LANLVN+F
Sbjct: 444 PFSAGMRICAGMELGKLQFSFSLANLVNAF 473
Score = 162 bits (410), Expect(2) = e-104
Identities = 75/145 (51%), Positives = 104/145 (71%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
S WPTGP P++GN++ L G L + L +A+ HG +MT+W G +P IVVSD +
Sbjct: 49 STMVWPTGPKTLPIIGNMHVLG-GTALQVVLHNLAKIHGNVMTIWIGSWRPVIVVSDIDR 107
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
AWEVLV K+SDYS+R MP ++KI SADW T++TS+ GP W LRKGLQ+ L P+ +++Q
Sbjct: 108 AWEVLVNKSSDYSARDMPEITKIISADWKTISTSDSGPGWSNLRKGLQNVALSPHNLAAQ 167
Query: 929 TQLQEKDIADLISSLEEEASLNNGV 855
+Q QEKDI +I SL++EA+ NNG+
Sbjct: 168 SQFQEKDITKMIQSLKKEAASNNGI 192
>gb|ADB89214.1| stylopine synthase [Papaver somniferum]
Length = 494
Score = 243 bits (621), Expect(2) = e-104
Identities = 125/270 (46%), Positives = 185/270 (68%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG +F DD + + M AIE+ +R++G L + F + +Y+PS K +++E QR+K+
Sbjct: 198 FGQDFD-DDKYVDDMHHAIEELIRVSGYAQLAEAFYYAKYLPSHKKAVRDVEEANQRVKK 256
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P+LS + P+ N YL FL SQ + E+++IF +FE + VDSTS TTAWALAF+I
Sbjct: 257 LVRPFLSLNPPT---NTYLHFLNSQKYDEEVIIFAIFEAYLLGVDSTSLTTAWALAFLIR 313
Query: 447 HENIQQRVLKQVKNRLGGTR-RMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
+Q ++ +++KN +V VED+ ++++Y+ AV+KET RM+PIAPLA+PH+A R
Sbjct: 314 EPVVQDKLYQELKNLTAKNDCEIVKVEDL-NKLQYLQAVLKETMRMKPIAPLAIPHKACR 372
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
D+ L+G K+ +GT V VN+YA+ H+EKVWKEP +FMPERFL + +G K ME+S +
Sbjct: 373 DTSLKGNKIDQGTQVMVNIYALHHNEKVWKEPFKFMPERFLQTQDVVNG---KGMEQSLL 429
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C MEL K + + +LANLVN+F
Sbjct: 430 PFSAGMRICAGMELGKLQFSFSLANLVNAF 459
Score = 162 bits (410), Expect(2) = e-104
Identities = 75/145 (51%), Positives = 104/145 (71%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
S WPTGP P++GN++ L G L + L +A+ HG +MT+W G +P IVVSD +
Sbjct: 35 STMVWPTGPKTLPIIGNMHVLG-GTALQVVLHNLAKIHGNVMTIWIGSWRPVIVVSDIDR 93
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
AWEVLV K+SDYS+R MP ++KI SADW T++TS+ GP W LRKGLQ+ L P+ +++Q
Sbjct: 94 AWEVLVNKSSDYSARDMPEITKIISADWKTISTSDSGPGWSNLRKGLQNVALSPHNLAAQ 153
Query: 929 TQLQEKDIADLISSLEEEASLNNGV 855
+Q QEKDI +I SL++EA+ NNG+
Sbjct: 154 SQFQEKDITKMIQSLKKEAASNNGI 178
>gb|AGL76711.1| (S)-canadine synthase, partial [Coptis chinensis]
Length = 491
Score = 236 bits (603), Expect(2) = e-102
Identities = 122/269 (45%), Positives = 182/269 (67%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG F D+ F E M IED +R++G L + F + +Y+PS K +E +K R++E
Sbjct: 195 FGQNFD-DNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPSHKKAEREAFLVKCRVQE 253
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P LS++ P++S YL FLLSQ F E+++IF +FEL+ VDSTS TT WALA++I
Sbjct: 254 LVRPLLSSNPPTNS---YLYFLLSQNFEEEVIIFCIFELYLLGVDSTSSTTTWALAYLIR 310
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
+ Q+++ + ++ LG +V +EDV ++++Y+ VVKET RM+PIAPLA+PH+ ++
Sbjct: 311 EQGAQEKLYQDIRMTLGDVD-LVKIEDV-NKLKYLQGVVKETMRMKPIAPLAIPHKTAKE 368
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFIP 88
+ L G KV +GT + VNLYA+ H++ +W +P +FMPERFL G++G + K ME+SF+P
Sbjct: 369 TTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFL-EGATGTAYN-KAMEQSFLP 426
Query: 87 FGAGRRSCPAMELAKAEVALTLANLVNSF 1
F AG R C M+L K + A LANLVN+F
Sbjct: 427 FSAGMRICAGMDLGKLQFAFALANLVNAF 455
Score = 165 bits (417), Expect(2) = e-102
Identities = 71/156 (45%), Positives = 115/156 (73%)
Frame = -1
Query: 1322 LMKLLDQTFFISKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGL 1143
++++L + + + +WP+GP + P++GNL+QL ++LH+ LAK+A+ HG +MT+W G
Sbjct: 21 IIRILFSSSSLPQMKWPSGPRKLPIIGNLHQLG-DDVLHVALAKLAKVHGSMMTIWIGSW 79
Query: 1142 QPSIVVSDHELAWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQS 963
+P IV+SD E AWEVLV K++DY +R MP ++KI SA WHT++TS+ GP+W+ +RKGLQS
Sbjct: 80 RPVIVISDLEKAWEVLVNKSADYGARDMPEITKIASASWHTISTSDAGPFWQNVRKGLQS 139
Query: 962 TTLHPNTISSQTQLQEKDIADLISSLEEEASLNNGV 855
+ P +++Q Q QE+ + LI ++ +EA+ NNG+
Sbjct: 140 GAMGPFNVAAQNQHQERGMKRLIKAMSDEAANNNGI 175
>sp|Q948Y1.1|C719A_COPJA RecName: Full=(S)-canadine synthase; AltName:
Full=(S)-tetrahydrocolumbamine oxidase
(methylenedioxy-bridge-forming); AltName:
Full=Cytochrome P450 719A1 gi|15822820|dbj|BAB68769.1|
methylenedioxy bridge-forming enzyme [Coptis japonica]
Length = 491
Score = 235 bits (599), Expect(2) = e-102
Identities = 122/269 (45%), Positives = 180/269 (66%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG F D+ F E M IED +R++G L + F + +Y+PS K +E +K R++E
Sbjct: 195 FGQAFD-DNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPSHKKAEREAFLVKCRVEE 253
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P LS+ P++S YL FLLSQ F E+++IF +FEL+ VDSTS TT WALA++I
Sbjct: 254 LVRPLLSSKPPTNS---YLYFLLSQNFEEEVIIFCIFELYLLGVDSTSSTTTWALAYLIR 310
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
+ Q+++ + ++ LG +V +EDV ++++Y+ VVKET RM+PIAPLA+PH+ ++
Sbjct: 311 EQGAQEKLYQDIRMTLGDVD-LVKIEDV-NKLKYLQGVVKETMRMKPIAPLAIPHKTAKE 368
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFIP 88
+ L G KV +GT + VNLYA+ H++ +W +P +FMPERFL G +G + K ME+SF+P
Sbjct: 369 TTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFL-EGETGTAYN-KAMEQSFLP 426
Query: 87 FGAGRRSCPAMELAKAEVALTLANLVNSF 1
F AG R C M+L K + A LANLVN+F
Sbjct: 427 FSAGMRICAGMDLGKLQFAFALANLVNAF 455
Score = 166 bits (420), Expect(2) = e-102
Identities = 71/156 (45%), Positives = 115/156 (73%)
Frame = -1
Query: 1322 LMKLLDQTFFISKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGL 1143
++++L + + + +WP+GP + P++GNL+QL ++LH+ LAK+A+ HG +MT+W G
Sbjct: 21 IIRILFSSSSLPQMKWPSGPRKLPIIGNLHQLG-DDVLHVALAKLAKVHGSVMTIWIGSW 79
Query: 1142 QPSIVVSDHELAWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQS 963
+P IV+SD E AWEVLV K++DY +R MP ++KI SA WHT++TS+ G +W+ +RKGLQS
Sbjct: 80 RPVIVISDIEKAWEVLVNKSADYGARDMPEITKIASASWHTISTSDAGSFWQNVRKGLQS 139
Query: 962 TTLHPNTISSQTQLQEKDIADLISSLEEEASLNNGV 855
+ P +++Q Q QE+D+ LI ++ +EA+ NNG+
Sbjct: 140 GAMGPLNVAAQNQYQERDMKRLIKAMSDEAANNNGI 175
>gb|AFI57927.1| cytochrome P450, partial [Papaver somniferum]
Length = 488
Score = 233 bits (593), Expect(2) = e-100
Identities = 123/270 (45%), Positives = 177/270 (65%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
+G +F DD + E M IE +R++G L +VF + +Y+PS K E K+R+
Sbjct: 196 YGQDFD-DDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPSHKRAVTGAEEAKRRVIA 254
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P+L ++ ++N YL FL SQ + E+++IF +FE + VDSTS TTAWALAF+I
Sbjct: 255 LVRPFLQSNP---ATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTAWALAFLIR 311
Query: 447 HENIQQRVLKQVKN-RLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
++Q+++ +++KN R M+ VEDV +++ Y+ AVVKET RM+PIAPLA+PH+A +
Sbjct: 312 EPSVQEKLYQELKNFTANNNRTMLKVEDV-NKLPYLQAVVKETMRMKPIAPLAIPHKACK 370
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
D+ L G KV +GT V VN++A+ H EKVWKEP +FMPERFL K ME+S +
Sbjct: 371 DTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFMPERFLQKHD-------KAMEQSLL 423
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C MEL K + + +LANLVN+F
Sbjct: 424 PFSAGMRICAGMELGKLQFSFSLANLVNAF 453
Score = 162 bits (411), Expect(2) = e-100
Identities = 74/145 (51%), Positives = 108/145 (74%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
S +WP GP P++GNL+ L G LH+ L K+A+ +G +MT+W G +P I+VSD +
Sbjct: 33 STTEWPVGPKTLPIIGNLHILG-GTALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDR 91
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
AWEVLV K+SDYS+R+MP ++KI +A+W T+++S+ GP+W TLRKGLQS L P ++SQ
Sbjct: 92 AWEVLVNKSSDYSAREMPEITKIGTANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQ 151
Query: 929 TQLQEKDIADLISSLEEEASLNNGV 855
T QE+DI LI +L++EA+LN+G+
Sbjct: 152 TAHQERDIIKLIKNLKDEAALNSGM 176
>sp|Q50LH3.1|C7192_ESCCA RecName: Full=(S)-stylopine synthase 1; Short=STS; AltName:
Full=Cytochrome P450 719A2; Short=EcCYP719A2;
Short=EcCYPB gi|63108256|dbj|BAD98250.1| stylopine
synthase [Eschscholzia californica]
Length = 495
Score = 230 bits (587), Expect(2) = e-100
Identities = 115/270 (42%), Positives = 185/270 (68%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG +F++D + + M AIE+ +R++G L + F + +Y+PS K +E+E ++R++
Sbjct: 198 FGQDFNNDK-YVDDMHLAIEELIRVSGYARLAEAFYYAKYLPSHKKAVREVEEAQRRVQN 256
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+SP+LS + P+ N YL FL SQ + ++++IF +FE + VDSTS TTAWALAF+I
Sbjct: 257 LVSPFLSLNPPT---NTYLHFLRSQKYDDEVIIFAIFEAYLLGVDSTSLTTAWALAFLIR 313
Query: 447 HENIQQRVLKQVKNRLG-GTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
N+Q+++ +++++ RR++ VED+ ++++Y+ AV+KET RM+PIAPLA+PH+A R
Sbjct: 314 EPNVQEKLYQELESFASKNDRRILKVEDI-NKLQYLQAVIKETMRMKPIAPLAIPHKACR 372
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
D+ L G K+ +GT V VN++A+ H++ V+ +P +FMPERF+ S A+ K ME+S +
Sbjct: 373 DTSLMGKKIDKGTRVMVNIFALHHNKNVFNDPFKFMPERFMKVDS--QDANGKAMEQSLL 430
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C MEL K + + LANL +F
Sbjct: 431 PFSAGMRICAGMELGKLQFSFALANLAYAF 460
Score = 163 bits (413), Expect(2) = e-100
Identities = 76/145 (52%), Positives = 103/145 (71%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
SK WP GP P++GN++ L G L + L +A+ HG +MT+W G +P IVVSD E
Sbjct: 35 SKMVWPAGPKTLPIIGNMHLLG-GTALQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIER 93
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
AWEVLV K+SDYS+R MP ++KI SADW T++TS+ GP+W LRKGLQ+ L P+ +++Q
Sbjct: 94 AWEVLVNKSSDYSARDMPDITKIISADWKTISTSDSGPHWTNLRKGLQNVALSPHNLAAQ 153
Query: 929 TQLQEKDIADLISSLEEEASLNNGV 855
Q QEKD+ +I +LEEEA NNG+
Sbjct: 154 FQFQEKDMTKMIQTLEEEARNNNGI 178
>sp|B5UAQ8.1|C7195_ESCCA RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
Full=Cytochrome P450 719A5 gi|209571368|dbj|BAG75113.1|
cheilanthifoline synthase [Eschscholzia californica]
Length = 490
Score = 225 bits (573), Expect(2) = e-100
Identities = 116/269 (43%), Positives = 174/269 (64%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG F+ D+ F + + A++D VR++G L D FKF +PS K +E+ + +R+
Sbjct: 192 FGQSFN-DENFVKGVHLALDDLVRISGYASLADAFKFCENLPSHKKSIREVHEVNERVVN 250
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ PYL + P+ N YL FL SQ F+++++I + E++ VDST+ T WAL F++
Sbjct: 251 LVKPYLVKNPPT---NTYLYFLNSQKFSDEVIISAVLEVYDLGVDSTASTAVWALTFLVR 307
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
+Q+++ K++ + GG R V VEDV S++ Y+ AV+KET RM+PIAP+A+PH+ RD
Sbjct: 308 EPRVQEKLYKEIIDLTGG-ERSVKVEDV-SKLPYLQAVMKETMRMKPIAPMAIPHKTSRD 365
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFIP 88
+ L G KV +GT + VNLYA+ H+ KV+ EP +F+PERFL S G D+K ME+S +P
Sbjct: 366 TSLMGKKVNKGTSIMVNLYAIHHNPKVFPEPYKFIPERFLQGQESKYG-DIKEMEQSLLP 424
Query: 87 FGAGRRSCPAMELAKAEVALTLANLVNSF 1
F AG R C MEL K + +LA+LV +F
Sbjct: 425 FSAGMRICAGMELGKLQYGFSLASLVEAF 453
Score = 168 bits (426), Expect(2) = e-100
Identities = 77/156 (49%), Positives = 112/156 (71%)
Frame = -1
Query: 1322 LMKLLDQTFFISKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGL 1143
+ KLL ++ IS +WP GP + P++GNL+QL GE H+ LA +A+ HG +MT+W G
Sbjct: 18 IAKLLKKSSSISTMEWPKGPKKLPIIGNLHQLG-GEAFHVVLANLAKIHGTVMTIWVGAW 76
Query: 1142 QPSIVVSDHELAWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQS 963
+P IV+SD + AWEVLV K+SDY+ R P ++KI SA+W ++ S+ GP+W+ LRKGLQ
Sbjct: 77 RPMIVISDIDKAWEVLVNKSSDYAGRDFPEITKIISANWKNISCSDSGPFWQNLRKGLQG 136
Query: 962 TTLHPNTISSQTQLQEKDIADLISSLEEEASLNNGV 855
L P + SQ QLQE+D+ +LI+S++E+AS NNG+
Sbjct: 137 GALAPLNVISQYQLQERDMKNLITSMQEKASKNNGI 172
>gb|ACO90219.1| stylopine synthase [Eschscholzia californica]
Length = 495
Score = 230 bits (587), Expect(2) = e-100
Identities = 115/270 (42%), Positives = 185/270 (68%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG +F++D + + M AIE+ +R++G L + F + +Y+PS K +E+E ++R++
Sbjct: 198 FGQDFNNDK-YVDDMHLAIEELIRVSGYARLAEAFYYAKYLPSHKKAVREVEEAQRRVQN 256
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+SP+LS + P+ N YL FL SQ + ++++IF +FE + VDSTS TTAWALAF+I
Sbjct: 257 LVSPFLSLNPPT---NTYLHFLRSQKYDDEVIIFAIFEAYLLGVDSTSLTTAWALAFLIR 313
Query: 447 HENIQQRVLKQVKNRLGGT-RRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
N+Q+++ +++++ R+++ VED+ ++++Y+ AV+KET RM+PIAPLA+PH+A R
Sbjct: 314 ESNVQEKLYQELESFASKMDRKILKVEDI-NKLQYLQAVIKETMRMKPIAPLAIPHKACR 372
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
D+ L G K+ +GT V VN+YA+ H++ V+ +P +FMPERF+ S A+ K ME+S +
Sbjct: 373 DTSLMGKKIDKGTRVMVNIYALHHNKNVFNDPFKFMPERFMKVDS--QDANGKAMEQSLL 430
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C MEL K + + LANL +F
Sbjct: 431 PFSAGMRICAGMELGKLQFSFALANLAYAF 460
Score = 162 bits (410), Expect(2) = e-100
Identities = 75/145 (51%), Positives = 103/145 (71%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
SK WP GP P++GN++ L G L + L +A+ HG +MT+W G +P IVVSD E
Sbjct: 35 SKMVWPAGPKTLPIIGNMHLLG-GTALQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIER 93
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
AWEVLV K+SDYS+R MP ++KI SADW T++TS+ GP+W LRKGLQ+ L P+ +++Q
Sbjct: 94 AWEVLVNKSSDYSARDMPDITKIISADWKTISTSDSGPHWTNLRKGLQNVALSPHNLAAQ 153
Query: 929 TQLQEKDIADLISSLEEEASLNNGV 855
Q QEKD+ +I +L+EEA NNG+
Sbjct: 154 FQFQEKDMTKMIQTLQEEARNNNGI 178
>dbj|BAF98470.1| cytochrome P450 [Coptis japonica var. dissecta]
Length = 491
Score = 242 bits (617), Expect(2) = 2e-98
Identities = 126/269 (46%), Positives = 180/269 (66%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FGP F +D F E + IED +RL+G L + F + +Y+PS K +E K RI+E
Sbjct: 195 FGPTFDNDK-FVESVLYEIEDVLRLSGYARLTEAFYYAKYLPSQKKVAREAYLAKYRIEE 253
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P LS++ P++S YL FL SQ ++++I+IF FELF VDSTS T WALA++IH
Sbjct: 254 LMRPLLSSNPPTNS---YLYFLQSQNYSKEIIIFCTFELFLLGVDSTSSTATWALAYLIH 310
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
+ +Q+++ + ++ +G +V +ED+ S+++Y+ AVVKET RM+PIAPLA+PH+ D
Sbjct: 311 EQAVQEKLNEDIRMTIGDVD-LVKIEDL-SKLKYLQAVVKETMRMKPIAPLAIPHKTAND 368
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFIP 88
+ L G KV GT + VNLYA+ H+E +W EP +FMPERFL A+ K ME+SF+P
Sbjct: 369 TTLMGTKVARGTQIMVNLYALHHNEDIWPEPYKFMPERFLQ--GENVSANNKAMEQSFLP 426
Query: 87 FGAGRRSCPAMELAKAEVALTLANLVNSF 1
FGAG R C M+L K ++A LANLVN+F
Sbjct: 427 FGAGMRICAGMDLGKLQIAFALANLVNAF 455
Score = 145 bits (367), Expect(2) = 2e-98
Identities = 65/145 (44%), Positives = 101/145 (69%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
SK++WP+GP R P++GNL+ L G+LLH+TLAK+A+ HG +MT+W G +P IV+SD
Sbjct: 32 SKKKWPSGPKRLPIIGNLHLLG-GDLLHVTLAKLAKVHGSVMTIWIGRWRPIIVISDINS 90
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
AWEVLV+K+++Y R P + K + + ++ S++GP+W +RKGLQ+ L P +++Q
Sbjct: 91 AWEVLVSKSAEYGQRDTPDIFKTLTVGQNNISMSDIGPFWHNVRKGLQNGALSPLNVAAQ 150
Query: 929 TQLQEKDIADLISSLEEEASLNNGV 855
TQ +E+D+ LI + EA NG+
Sbjct: 151 TQFREEDVKRLIHEMSREALNKNGI 175
>sp|Q50LH4.1|C7193_ESCCA RecName: Full=(S)-stylopine synthase 2; Short=STS; AltName:
Full=Cytochrome P450 719A3; Short=EcCYP719A3;
Short=EcCYPA gi|63108254|dbj|BAD98249.1| stylopine
synthase [Eschscholzia californica]
Length = 495
Score = 225 bits (574), Expect(2) = 3e-98
Identities = 117/270 (43%), Positives = 179/270 (66%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG +F +D + E M AIE+ +R++G L + F + +Y+PS + + +E LKQ +K
Sbjct: 198 FGRDFE-EDKYVEDMHHAIEELIRISGYARLAEAFYYAKYLPSHRKAVRYVEELKQIVKN 256
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
LI P+LS + P+ N YL FL SQ + E++VIF +FE + VDSTS TTAWALA+++
Sbjct: 257 LIRPFLSVNPPT---NTYLHFLRSQNYDEEVVIFAIFETYLLGVDSTSSTTAWALAYLVR 313
Query: 447 HENIQQRVLKQVKN-RLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
++Q R+ +++ + R+++ VED+ ++++Y+ AV+KET RM+PIAPLA+PH+A +
Sbjct: 314 EPSVQDRLHQELDHFAKQNDRKILKVEDM-NKLQYLQAVIKETMRMKPIAPLAIPHKACK 372
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
D+ L G K+ +GT V VNLYA+ H++ V+ +P +FMPERFL A K ME+S +
Sbjct: 373 DTSLMGNKINKGTRVMVNLYALHHNKNVFNDPFKFMPERFLK--VDNQDAKGKAMEQSLL 430
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C MEL K + + LANL+ +F
Sbjct: 431 PFSAGMRICAGMELGKLQFSFALANLIFAF 460
Score = 162 bits (409), Expect(2) = 3e-98
Identities = 74/141 (52%), Positives = 101/141 (71%)
Frame = -1
Query: 1277 WPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHELAWEV 1098
WP GP P++GN++ L G L + L +A+ HGR+MT+W G +P IVVSD E AWEV
Sbjct: 39 WPEGPKTLPIIGNMHLLG-GTALQVVLYNLAKVHGRVMTIWIGSWRPVIVVSDIEQAWEV 97
Query: 1097 LVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQTQLQ 918
LV K+SDYS+R MP ++KI +ADW T++TS+ GP+W LRKGLQ+ + PN +++Q Q Q
Sbjct: 98 LVNKSSDYSARDMPDITKIVTADWRTISTSDSGPHWSNLRKGLQNIAISPNNLAAQFQFQ 157
Query: 917 EKDIADLISSLEEEASLNNGV 855
EKDI +I LE+EA NNG+
Sbjct: 158 EKDIIKMIQILEQEAKDNNGI 178
>gb|AFB74615.1| cytochrome P450 [Papaver somniferum]
Length = 486
Score = 229 bits (585), Expect(2) = 1e-97
Identities = 121/270 (44%), Positives = 176/270 (65%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
+G +F DD + E M IE +R++G L +VF + +Y+P K E K+R+
Sbjct: 194 YGQDFD-DDKYVEDMHDVIEFLIRISGYAQLAEVFYYAKYLPGHKRAVTGAEEAKRRVIA 252
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P+L ++ ++N YL FL SQ + E+++IF +FE + VDSTS TTAWALAF+I
Sbjct: 253 LVRPFLQSNP---ATNTYLHFLKSQLYPEEVIIFAIFEAYLLGVDSTSSTTAWALAFLIR 309
Query: 447 HENIQQRVLKQVKN-RLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
++Q+++ +++KN R M+ VEDV +++ Y+ AVVKET RM+PIAPLA+PH+A +
Sbjct: 310 EPSVQEKLYQELKNFTANNNRTMLKVEDV-NKLPYLQAVVKETMRMKPIAPLAIPHKACK 368
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
D+ L G KV +GT V VN++A+ H EKVWKEP +F+PERFL K ME+S +
Sbjct: 369 DTSLMGKKVDKGTKVMVNIHALHHTEKVWKEPYKFIPERFLQKHD-------KAMEQSLL 421
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C MEL K + + +LANLVN+F
Sbjct: 422 PFSAGMRICAGMELGKLQFSFSLANLVNAF 451
Score = 155 bits (393), Expect(2) = 1e-97
Identities = 71/140 (50%), Positives = 103/140 (73%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
S +WP GP P++GNL+ L G LH+ L K+A+ +G +MT+W G +P I+VSD +
Sbjct: 33 STTEWPVGPKTLPIIGNLHILG-GTALHVVLHKLAEVYGSVMTIWIGSWKPVIIVSDFDR 91
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
AWEVLV K+SDYS+R+MP ++KI +A+W T+++S+ GP+W TLRKGLQS L P ++SQ
Sbjct: 92 AWEVLVNKSSDYSAREMPEITKIGTANWRTISSSDSGPFWATLRKGLQSVALSPQHLASQ 151
Query: 929 TQLQEKDIADLISSLEEEAS 870
T QE+DI LI +L++EA+
Sbjct: 152 TAHQERDIIKLIKNLKDEAA 171
>sp|B1NF20.1|C719E_ARGME RecName: Full=Cheilanthifoline synthase; Short=CHS; AltName:
Full=Cytochrome P450 719A14 gi|148841094|gb|ABR14722.1|
cheilanthifoline synthase [Argemone mexicana]
Length = 494
Score = 224 bits (571), Expect(2) = 2e-96
Identities = 116/270 (42%), Positives = 177/270 (65%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG +F + L M A++D VR++G L D FKF +PS K +E+ +K+R++
Sbjct: 195 FGQDFQDEKLVVG-MHHALDDLVRISGYASLADAFKFCENLPSHKKSIREVHEVKKRVEN 253
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
LI P++ ++ P+ N YL FL +Q F EDI+I + E++ VDST+ TT WAL F++
Sbjct: 254 LIRPHIVSNPPT---NTYLYFLKTQDFNEDIIISAILEVYDLGVDSTASTTVWALTFLVR 310
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
+ IQ+++ +++ N GG +R V VEDV ++M Y+ AV+KET RM+PIAP+A+PH+ +D
Sbjct: 311 EQEIQEKLYREIVNVTGG-KRSVKVEDV-NKMPYLQAVMKETMRMKPIAPMAIPHKTSKD 368
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDG-ADVKRMERSFI 91
+ L G K+ +G+ + VNLYA+ H+ KV+ EP +FMPERFL +S + ++K ME S +
Sbjct: 369 TSLMGKKINKGSVIMVNLYAIHHNPKVFPEPYKFMPERFLKDVNSDESLGNIKTMESSLL 428
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
F AG R C MEL K ++A LA+LV+ F
Sbjct: 429 AFSAGMRICAGMELGKLQLAFGLASLVHEF 458
Score = 157 bits (396), Expect(2) = 2e-96
Identities = 69/146 (47%), Positives = 105/146 (71%)
Frame = -1
Query: 1292 ISKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHE 1113
+S +WP GP + P++GNL+QL G++ H+ LA +A+ +G + T+W G +P I+VSD +
Sbjct: 31 LSTMEWPVGPKKLPIIGNLHQLG-GDVFHVVLANLAKVYGSVFTIWVGSWRPMIIVSDID 89
Query: 1112 LAWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISS 933
AWEVLV K+SDYS+R MP ++KI SA+W ++ S+ GP+W LRKGLQ L P ++S
Sbjct: 90 KAWEVLVNKSSDYSARDMPDITKIISANWKNISCSDSGPFWHNLRKGLQGVALTPLNVAS 149
Query: 932 QTQLQEKDIADLISSLEEEASLNNGV 855
Q LQE+D+ +LI+S+ ++AS NG+
Sbjct: 150 QYHLQERDMKNLINSMYKDASRKNGI 175
>dbj|BAG75116.1| cytochrome P450 [Eschscholzia californica]
Length = 495
Score = 229 bits (584), Expect(2) = 3e-96
Identities = 116/269 (43%), Positives = 175/269 (65%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG +F+ DD + E + AIE+ +R++G L + F + +Y+PS K + E KQ +
Sbjct: 198 FGQDFN-DDKYVEDLHQAIEELIRMSGYAQLAEAFYYAKYLPSHKKAIRHAELTKQIVTN 256
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P+LS + P++S YL FL SQ + E++VIF +FE + VDSTS TTAWALA+++
Sbjct: 257 LVRPFLSLNPPTNS---YLHFLQSQKYDEEMVIFAIFETYLLGVDSTSSTTAWALAYLVR 313
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
N+Q R+ ++ N R + +V ++++Y+ AV KET RM+PIAPLA+PH+A RD
Sbjct: 314 EPNVQDRLYNELNNYANYNDRKILKVEVINKLQYLQAVTKETMRMKPIAPLAIPHKACRD 373
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFIP 88
+ L G K+ +GT V VNL+A+ H+E V+ +P +FMPERFL + + ++K ME+S +P
Sbjct: 374 TSLMGTKIDKGTKVMVNLHALHHNENVFTDPFKFMPERFLK--VNNEDVNMKAMEQSLLP 431
Query: 87 FGAGRRSCPAMELAKAEVALTLANLVNSF 1
F AG R C MEL K + + LANLV +F
Sbjct: 432 FSAGMRICAGMELGKLQFSFALANLVYAF 460
Score = 151 bits (381), Expect(2) = 3e-96
Identities = 71/145 (48%), Positives = 98/145 (67%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
SK WP GP P++GN++ L G L + L +A+ HG +MT+W G +P IVVSD E
Sbjct: 35 SKMVWPQGPKTLPIIGNMHLLG-GTALQVVLHNLAKVHGSVMTIWIGSWRPVIVVSDIER 93
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
AWEVLV K+SDYS+R++P + K +AD T+AT + GP+W LRKGLQ+ L PN +++Q
Sbjct: 94 AWEVLVNKSSDYSARELPDIIKYNTADCRTIATCDSGPHWSNLRKGLQNVALSPNNLAAQ 153
Query: 929 TQLQEKDIADLISSLEEEASLNNGV 855
Q QEKD+ +I LE+EA NG+
Sbjct: 154 FQFQEKDVIKMIDILEQEAINKNGI 178
>dbj|BAF98471.1| cytochrome P450 [Coptis japonica var. dissecta]
Length = 508
Score = 232 bits (592), Expect(2) = 3e-95
Identities = 126/269 (46%), Positives = 176/269 (65%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FGP F+ D F E M IED +R + L + F + +Y+PS + +E + K RI+E
Sbjct: 211 FGPSFN-DSKFIESMLYEIEDFIRTSSYTSLTNSFYYAKYLPSQRKATREAKLGKYRIEE 269
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P LS+ P+ N YL FLLSQ +E++ IF +FELF VDS S TT WALA+MI
Sbjct: 270 LVRPLLSSKPPT---NAYLYFLLSQNLSEEVTIFCIFELFLLGVDSASSTTTWALAYMIR 326
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
+ Q+++ + ++ +G +V +EDV ++++Y+ +VVKET RM+PIAPLA+PH A +D
Sbjct: 327 EQEAQEKLYQDIRMTIGDVD-LVKIEDV-NKLKYLQSVVKETMRMKPIAPLALPHNAGKD 384
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFIP 88
+ L G K+ +GT V VNLYA+ H E VW EP++FMPER+L G G K ME+S +P
Sbjct: 385 TTLMGTKIVKGTRVMVNLYALHHYEDVWLEPSKFMPERYL-QGEDG-SVTHKAMEQSLLP 442
Query: 87 FGAGRRSCPAMELAKAEVALTLANLVNSF 1
FGAG R C M+L K +VA LANLVN+F
Sbjct: 443 FGAGMRICAGMDLGKLQVAFVLANLVNAF 471
Score = 145 bits (365), Expect(2) = 3e-95
Identities = 67/147 (45%), Positives = 104/147 (70%), Gaps = 3/147 (2%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
S+ WP+GP + P++GNL+QL RGELLH+TLAK+A+ HG +MT+W G P IV+SD
Sbjct: 45 SQMTWPSGPKKLPIIGNLHQL-RGELLHVTLAKLAKVHGGVMTIWMGSWVPIIVISDINS 103
Query: 1109 AWEVLVTKASDYSSRKMPYVSKI---TSADWHTLATSNLGPYWETLRKGLQSTTLHPNTI 939
AWEVLV K++DY +R++ Y+ ++ ++ H +++S++GP W +RKGLQS L P ++
Sbjct: 104 AWEVLVNKSADYGAREVTYLHELLRDSAMHPHNISSSDVGPLWHNIRKGLQSGALSPLSV 163
Query: 938 SSQTQLQEKDIADLISSLEEEASLNNG 858
+SQTQ +E+D+ ++ + E NNG
Sbjct: 164 ASQTQHRERDMKRVVHEMSREIVNNNG 190
>gb|ADB89213.1| cheilanthifoline synthase [Papaver somniferum]
Length = 492
Score = 224 bits (570), Expect(2) = 3e-95
Identities = 116/270 (42%), Positives = 176/270 (65%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG +F +D F M A+++ V ++G L D FKF +PS K + + ++K R
Sbjct: 193 FGQDFVDED-FVVGMHQALDELVSISGYASLADAFKFCENLPSHKKTVRAVHAIKIRFDN 251
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
LI P++ ++ P+ N YL FLLSQ F+ED++I + E++ VDST+ TT WAL F++
Sbjct: 252 LIRPHIVSNPPT---NTYLHFLLSQDFSEDVIISAILEVYDLGVDSTASTTVWALTFLVR 308
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
+ IQ+++ +++ N GG ++ V VED+ +++ Y+ AV+KET RM+PIAP+A+PH+A +D
Sbjct: 309 EQKIQEKLYREINNVTGG-KKPVKVEDL-NKLPYLQAVMKETMRMKPIAPMAIPHKASKD 366
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLM-SGSSGDGADVKRMERSFI 91
+ L G K+ +G V VNLYA+ H+ V+ EP +FMPERFL + S G D+K+ME S +
Sbjct: 367 TSLMGKKINKGAVVMVNLYAIHHNPAVFPEPYKFMPERFLKDANSDGSLGDIKKMESSLL 426
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
F AG R C MEL K ++A LA+LVN F
Sbjct: 427 AFSAGMRICAGMELGKLQLAFGLASLVNEF 456
Score = 153 bits (387), Expect(2) = 3e-95
Identities = 69/146 (47%), Positives = 103/146 (70%)
Frame = -1
Query: 1292 ISKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHE 1113
+S +WP+GP P++GNL+QL GE H+ LA +A+ +G + T+W G +P IV+SD +
Sbjct: 29 MSTMEWPSGPKTLPIIGNLHQLG-GEAFHVCLANLAKVYGGVFTIWVGSWRPFIVISDVD 87
Query: 1112 LAWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISS 933
AWEVLV K+SDYS+R MP ++KI SA+W ++ + GP+W LRKGLQ L P ++S
Sbjct: 88 KAWEVLVNKSSDYSARDMPDITKIISANWKNISHGDSGPFWHNLRKGLQGVALTPFNVAS 147
Query: 932 QTQLQEKDIADLISSLEEEASLNNGV 855
Q LQE+D+ +LI S++++AS NG+
Sbjct: 148 QYHLQERDMQNLIKSMKKKASQKNGI 173
>dbj|BAG75114.1| cytochrome P450 [Eschscholzia californica]
Length = 495
Score = 225 bits (573), Expect(2) = 1e-94
Identities = 114/270 (42%), Positives = 177/270 (65%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG +F +D + E++ I++ +R++G L + F + RY+P+ K KQ +
Sbjct: 199 FGQDFD-EDTYVEKLHHTIDELIRMSGYAQLAEAFYYARYLPNHKKAVNHAAKTKQIVTH 257
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P+LS + P++S YL FL SQ + E+++IF++FE++ VDSTS TTAWALA+++
Sbjct: 258 LMRPFLSLNPPTNS---YLHFLQSQNYDEELIIFSIFEVYLLGVDSTSSTTAWALAYLVR 314
Query: 447 HENIQQRVLKQVKN-RLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
N+Q+ + +++ N R+++ VED+ ++++Y+ AV KET RM+PIAPLA+PH+A R
Sbjct: 315 EPNVQETLYQELDNFAKQNDRKILKVEDI-NKLQYLQAVTKETMRMKPIAPLAIPHKASR 373
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
D+ L G KV +GT V VNL+A+ H+E V+ +P +FMPERFL S GA K ME+S++
Sbjct: 374 DTTLMGKKVEKGTKVMVNLHALHHNENVFNDPYKFMPERFL---KSYQGAKAKAMEQSYL 430
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C ME+ K + LANL +F
Sbjct: 431 PFSAGMRICGGMEVGKLQFGFALANLAYAF 460
Score = 150 bits (378), Expect(2) = 1e-94
Identities = 67/145 (46%), Positives = 100/145 (68%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
S +WP GP P++GN++ L + L + L +A+ +G +MT+W G +P I+VSD E
Sbjct: 35 SNTEWPNGPKTLPIIGNMHLLGGTKALQVILHNLAKVYGGVMTIWIGSWRPVIIVSDIER 94
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
AWEVLV K+SDYS+R++P + K +A++ T+AT + GP+W LRKGLQ+ L P+ +++Q
Sbjct: 95 AWEVLVNKSSDYSARELPEIIKYNAANFRTIATCDSGPHWSNLRKGLQNVALSPHNLAAQ 154
Query: 929 TQLQEKDIADLISSLEEEASLNNGV 855
Q QEKDI +I +LE EA NNG+
Sbjct: 155 FQFQEKDITKMIQNLEVEAKNNNGI 179
>dbj|BAG75115.1| cytochrome P450 [Eschscholzia californica]
Length = 494
Score = 224 bits (570), Expect(2) = 2e-93
Identities = 114/270 (42%), Positives = 174/270 (64%), Gaps = 1/270 (0%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FGP F+ DD + E M I++ ++++ L + F + +Y+PS + + E KQ +K+
Sbjct: 199 FGPNFN-DDQYVEDMHNTIDELIQMSSYAQLAEAFYYAKYLPSHRKAVRHFEQTKQIVKK 257
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
LI PY+S P N YL FL SQ + E++VIF +FE + VDSTS TT WALAF+I
Sbjct: 258 LIRPYISVSPPP---NTYLHFLQSQNYDEEVVIFAIFEAYLLGVDSTSSTTTWALAFLIR 314
Query: 447 HENIQQRVLKQVKNRLG-GTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVR 271
N+Q+++ +++KN R ++ VED+ ++++Y+ AV KET RM+P+APLA+PH+A R
Sbjct: 315 EPNVQEKLYQELKNFAEQNDREIMKVEDI-NKLQYLQAVTKETMRMKPVAPLAIPHKACR 373
Query: 270 DSELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFI 91
++ L G+ + +GT V VN++++ H+E V+ +P FMPERFL D +VK ME+S++
Sbjct: 374 ETSLMGMPIDKGTKVMVNIHSLHHNENVFSDPFTFMPERFL----KVDNQNVKAMEQSYL 429
Query: 90 PFGAGRRSCPAMELAKAEVALTLANLVNSF 1
PF AG R C +EL K LANLV +F
Sbjct: 430 PFSAGMRICAGIELGKLHFGFALANLVYAF 459
Score = 147 bits (372), Expect(2) = 2e-93
Identities = 69/145 (47%), Positives = 96/145 (66%)
Frame = -1
Query: 1289 SKQQWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHEL 1110
SK WP GP P++GN++ L + L + L +++ HG +MT+W G +P IVVS+ E
Sbjct: 35 SKMVWPKGPKTLPIIGNMHLLGGSKALQVILHNLSKVHGSVMTIWIGRWRPVIVVSNIER 94
Query: 1109 AWEVLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQ 930
WEVLV K+SDYS R +P V K SAD+ T++TS+ GP+W LRKGLQ+ L PN++++Q
Sbjct: 95 VWEVLVNKSSDYSGRYVPDVIKFVSADFRTISTSDSGPHWTNLRKGLQNVALSPNSLAAQ 154
Query: 929 TQLQEKDIADLISSLEEEASLNNGV 855
Q QEKDI + LE EA N G+
Sbjct: 155 FQFQEKDIIKMTDILEREARNNKGI 179
>gb|AGC29953.1| CYP719A23 [Sinopodophyllum hexandrum]
Length = 489
Score = 219 bits (559), Expect(2) = 4e-90
Identities = 119/269 (44%), Positives = 171/269 (63%)
Frame = -3
Query: 807 FGPEFSSDDLFAERMDCAIEDQVRLTGKPGLVDVFKFTRYIPSLKPPFKELESLKQRIKE 628
FG F +D + + M ++D R G L F F +++PS K KE K++I +
Sbjct: 194 FGDTFDNDP-YNDSMHEVVQDLNRFGGIALLEQAFSFAKHLPSYKRGVKEFHIHKRKIDD 252
Query: 627 LISPYLSTHKPSSSSNCYLSFLLSQGFTEDIVIFNLFELFTFAVDSTSCTTAWALAFMIH 448
L+ P +++ P S+S YL FL SQ ++E+I+I +FEL+ A+DS++ T WALAFMI
Sbjct: 253 LVRPVVASANPPSNS--YLGFLQSQNYSEEIIIACIFELYLLAMDSSASTATWALAFMIR 310
Query: 447 HENIQQRVLKQVKNRLGGTRRMVSVEDVTSEMEYVHAVVKETTRMRPIAPLAVPHRAVRD 268
+ +Q+++ + +K +G +V ED+ S+M Y+ AVVKET RM+PIAPLA+PH+ D
Sbjct: 311 DQQVQEKLYQDIKRVIGDGVDLVKAEDL-SKMHYLQAVVKETMRMKPIAPLAIPHKTAID 369
Query: 267 SELQGVKVREGTPVSVNLYAMLHDEKVWKEPNRFMPERFLMSGSSGDGADVKRMERSFIP 88
+ + G KV +GT V VNLYA+ HDE VW +P FMPERFL DG V E++F+P
Sbjct: 370 TTVMGTKVPKGTCVMVNLYALHHDESVWAKPYTFMPERFL---QGEDGKSV--TEQAFLP 424
Query: 87 FGAGRRSCPAMELAKAEVALTLANLVNSF 1
FGAG R C ME+ K + +L LANLVN+F
Sbjct: 425 FGAGMRICGGMEVGKLQFSLALANLVNAF 453
Score = 140 bits (353), Expect(2) = 4e-90
Identities = 67/142 (47%), Positives = 99/142 (69%)
Frame = -1
Query: 1280 QWPTGPTRFPLVGNLYQLSRGELLHLTLAKMAQKHGRIMTVWFGGLQPSIVVSDHELAWE 1101
+WP GP P++GNL+QL G+ LH+ LAK+A+ HG IMT+W +P IVVSD WE
Sbjct: 35 KWPPGPKTLPIIGNLHQLG-GDELHIVLAKLARVHGAIMTIWMAK-KPVIVVSDVNSVWE 92
Query: 1100 VLVTKASDYSSRKMPYVSKITSADWHTLATSNLGPYWETLRKGLQSTTLHPNTISSQTQL 921
VLV+K+SDY++R +SKI SA H++ TS+ GPYW+TLR+GL L P IS+Q +
Sbjct: 93 VLVSKSSDYAARDAAEISKIVSASSHSINTSDSGPYWQTLRRGLTHGPLGPLNISAQIPI 152
Query: 920 QEKDIADLISSLEEEASLNNGV 855
Q++D+ +I ++++A+ N G+
Sbjct: 153 QQRDMQRVIREMQQDAAANGGI 174