BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Catharanthus23_contig00008528
         (1980 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q03163.1|HMDH_CATRO RecName: Full=3-hydroxy-3-methylglutaryl-...   620   0.0  
gb|AAT52222.1| hydroxymethylglutaryl-CoA reductase [Catharanthus...   618   0.0  
gb|ADR51242.1| 3-hydroxy-3-methylglutaryl-CoA reductase, partial...   462   0.0  
gb|AAO85554.1| 3-hydroxy-3-methylglutaryl-CoA reductase [Nicotia...   447   0.0  
ref|XP_004232593.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzy...   443   0.0  
gb|AAL54878.1|AF004232_1 hydroxy-methyl-glutaryl-coenzyme A redu...   448   0.0  
sp|Q01559.1|HMDH_NICSY RecName: Full=3-hydroxy-3-methylglutaryl-...   446   0.0  
gb|AAB87727.1| hydroxy-methylglutaryl-coenzyme A reductase [Nico...   446   0.0  
ref|NP_001275084.1| 3-hydroxy-3-methylglutaryl-coenzyme A reduct...   441   0.0  
gb|AAL54879.1|AF004233_1 hydroxy-methyl-glutaryl-coenzyme A redu...   448   0.0  
gb|AEX26934.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase 1...   442   0.0  
ref|XP_006364832.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzy...   438   0.0  
ref|NP_001275461.1| 3-hydroxy-3-methylglutaryl-coenzyme A reduct...   441   0.0  
ref|XP_004231636.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzy...   438   0.0  
dbj|BAB20771.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase ...   438   0.0  
ref|XP_006350440.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzy...   432   0.0  
sp|Q9XEL8.1|HMDH2_CAPAN RecName: Full=3-hydroxy-3-methylglutaryl...   436   0.0  
sp|P48022.1|HMDH2_SOLLC RecName: Full=3-hydroxy-3-methylglutaryl...   431   0.0  
gb|ADN39417.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [...   434   0.0  
dbj|BAE92730.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase ...   418   0.0  

>sp|Q03163.1|HMDH_CATRO RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase;
            Short=HMG-CoA reductase gi|167488|gb|AAA33108.1|
            hydroxymethylglutaryl-CoA reductase [Catharanthus roseus]
            gi|445621|prf||1909368A hydroxy methylglutaryl CoA
            reductase
          Length = 601

 Score =  620 bits (1598), Expect(2) = 0.0
 Identities = 312/325 (96%), Positives = 312/325 (96%)
 Frame = +1

Query: 133  MDSRRRSPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSVMY 312
            MDSRRRSPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSVMY
Sbjct: 1    MDSRRRSPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSVMY 60

Query: 313  FLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNEGWEI 492
            FLLTRWREKIRNATPLHVVT             VIYLVSFFGLDFVQSLIYKPNNEGWEI
Sbjct: 61   FLLTRWREKIRNATPLHVVTLSELAALASLIASVIYLVSFFGLDFVQSLIYKPNNEGWEI 120

Query: 493  EEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLITPQNSEED 672
            EEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLITPQNSEED
Sbjct: 121  EEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLITPQNSEED 180

Query: 673  EDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDYASILGQC 852
            EDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDYASILGQC
Sbjct: 181  EDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDYASILGQC 240

Query: 853  CEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGANSVLLRD 1032
            CEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGANSVLLRD
Sbjct: 241  CEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGANSVLLRD 300

Query: 1033 GMTRAPVVRFGTAKRAAELKFYMED 1107
            GMTRAPVVRFGTAKRAAELKFYMED
Sbjct: 301  GMTRAPVVRFGTAKRAAELKFYMED 325



 Score =  462 bits (1189), Expect(2) = 0.0
 Identities = 241/253 (95%), Positives = 241/253 (95%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA
Sbjct: 349  QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 408

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKN            FNAHAS
Sbjct: 409  AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNLAGSAIAGALGGFNAHAS 468

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS
Sbjct: 469  NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 528

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD
Sbjct: 529  ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 588

Query: 1853 ITNIASSQLESDS 1891
            ITNIASSQLESDS
Sbjct: 589  ITNIASSQLESDS 601


>gb|AAT52222.1| hydroxymethylglutaryl-CoA reductase [Catharanthus roseus]
          Length = 601

 Score =  618 bits (1594), Expect(2) = 0.0
 Identities = 311/325 (95%), Positives = 311/325 (95%)
 Frame = +1

Query: 133  MDSRRRSPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSVMY 312
            MDSRRRSPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSVMY
Sbjct: 1    MDSRRRSPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSVMY 60

Query: 313  FLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNEGWEI 492
            FLLTRWREKIRNATPLHVVT             VIYLV FFGLDFVQSLIYKPNNEGWEI
Sbjct: 61   FLLTRWREKIRNATPLHVVTLSELAALASLIASVIYLVGFFGLDFVQSLIYKPNNEGWEI 120

Query: 493  EEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLITPQNSEED 672
            EEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLITPQNSEED
Sbjct: 121  EEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLITPQNSEED 180

Query: 673  EDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDYASILGQC 852
            EDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDYASILGQC
Sbjct: 181  EDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDYASILGQC 240

Query: 853  CEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGANSVLLRD 1032
            CEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGANSVLLRD
Sbjct: 241  CEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGANSVLLRD 300

Query: 1033 GMTRAPVVRFGTAKRAAELKFYMED 1107
            GMTRAPVVRFGTAKRAAELKFYMED
Sbjct: 301  GMTRAPVVRFGTAKRAAELKFYMED 325



 Score =  459 bits (1180), Expect(2) = 0.0
 Identities = 238/253 (94%), Positives = 240/253 (94%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA
Sbjct: 349  QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 408

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKN            FNAHAS
Sbjct: 409  AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNLAGSAIAGALGGFNAHAS 468

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMP+IEVG VGGGTQLASQS
Sbjct: 469  NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPAIEVGAVGGGTQLASQS 528

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD
Sbjct: 529  ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 588

Query: 1853 ITNIASSQLESDS 1891
            ITN+ASSQLESDS
Sbjct: 589  ITNVASSQLESDS 601


>gb|ADR51242.1| 3-hydroxy-3-methylglutaryl-CoA reductase, partial [Coffea arabica]
          Length = 604

 Score =  462 bits (1188), Expect(2) = 0.0
 Identities = 239/336 (71%), Positives = 275/336 (81%), Gaps = 11/336 (3%)
 Frame = +1

Query: 133  MDSRRR--SPTVTAKAAAGELPLAPHEGQNQQPSIP--RSSDVLPLPLYLANGVFFTLFF 300
            MD RRR  +P +  KA AGE  + PH+    Q   P  ++SD LPLPL+L NG+FFT+FF
Sbjct: 1    MDVRRRPANPILREKADAGEQLIKPHKSHQHQQQHPPMKASDALPLPLHLTNGLFFTIFF 60

Query: 301  SVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNE 480
            SVMYFLL+RWREKIRN+ PLHVVT             VIYL+ FFG+ FVQ+LI +PN +
Sbjct: 61   SVMYFLLSRWREKIRNSIPLHVVTLSELVAVLSLIASVIYLLGFFGIGFVQTLISRPNPD 120

Query: 481  GWEIEEE----ILMVEDSRNGTNCTTLGCAVPPPSVP--KIAPVVPQQPSKMVI-IEKPA 639
            GW++E+E     L+ EDSR+GT CTTLGCAVPPP VP  K  P + Q  +K  + +EKPA
Sbjct: 121  GWDVEDENTEQFLLQEDSRSGT-CTTLGCAVPPPPVPSAKGLPKISQPAAKAAMAVEKPA 179

Query: 640  PLITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLE 819
            PLITPQ+SEEDE+IIK+VV+GKIPSYSLESKLGDCK+AAGIRREALQRITGKSLEGLPLE
Sbjct: 180  PLITPQDSEEDEEIIKSVVSGKIPSYSLESKLGDCKKAAGIRREALQRITGKSLEGLPLE 239

Query: 820  GFDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILA 999
            GFDY SILGQCCEMPVGYVQLPVGIAGPLLLDGREYM+PMATTEGCLVASTNRGCKAI+A
Sbjct: 240  GFDYESILGQCCEMPVGYVQLPVGIAGPLLLDGREYMVPMATTEGCLVASTNRGCKAIMA 299

Query: 1000 SGGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            SGGA S+LLRDGMTRAPVVRF TAKRAAELKF++E+
Sbjct: 300  SGGATSMLLRDGMTRAPVVRFATAKRAAELKFFVEE 335



 Score =  415 bits (1067), Expect(2) = 0.0
 Identities = 208/246 (84%), Positives = 227/246 (92%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RFSCSTGDAMGMNMVSKGVQNVL++LQTD+PDMDV+G+SGNFCADKKPA
Sbjct: 359  QCAIAGKNLYMRFSCSTGDAMGMNMVSKGVQNVLDYLQTDFPDMDVIGLSGNFCADKKPA 418

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAIIKEEIVK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 419  AVNWIEGRGKSVVCEAIIKEEIVKKVLKTEVAALVELNMLKNLTGSAMAGSLGGFNAHAS 478

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA++IATGQDPAQNVESS CITMMEAVNDGKDLH+SV+MPSIEVGTVGGGT+LASQS
Sbjct: 479  NIVSAVYIATGQDPAQNVESSHCITMMEAVNDGKDLHVSVSMPSIEVGTVGGGTKLASQS 538

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLL VKGA+K+  GAN+RLLAT+VAGSVLAGELSLMSAISAGQLV SHMKYNRSSKD
Sbjct: 539  ACLNLLRVKGANKEEAGANARLLATVVAGSVLAGELSLMSAISAGQLVSSHMKYNRSSKD 598

Query: 1853 ITNIAS 1870
            +T +AS
Sbjct: 599  VTKVAS 604


>gb|AAO85554.1| 3-hydroxy-3-methylglutaryl-CoA reductase [Nicotiana attenuata]
          Length = 604

 Score =  447 bits (1149), Expect(2) = 0.0
 Identities = 234/336 (69%), Positives = 268/336 (79%), Gaps = 11/336 (3%)
 Frame = +1

Query: 133  MDSRRRSPTV---TAKAAAGELPLAPHEGQNQQP-SIPRSSDVLPLPLYLANGVFFTLFF 300
            MD RRRS      T +  AGE PL PH+ Q +Q  S+  +SD LPLPLYL NG+FFT+FF
Sbjct: 1    MDVRRRSDKPAYPTKEFTAGEKPLKPHKQQQEQDNSLLIASDALPLPLYLTNGLFFTMFF 60

Query: 301  SVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNE 480
            SVMY+LL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQS + + NN+
Sbjct: 61   SVMYYLLSRWREKIRNSTPLHVVTFSELVAIISLIASVIYLLGFFGIGFVQSFVSRDNND 120

Query: 481  -GWEIEEE----ILMVEDSRNGTNCTTLGC-AVPPPSVPKIAPVVPQQPSKMVII-EKPA 639
              W++E+E     L+ EDSR G   TTLGC AVPPP   +  P+VP QP+K+  + EKPA
Sbjct: 121  DSWDVEDENDEQFLLEEDSRRGP-ATTLGCTAVPPPPARQFVPMVPPQPAKIAAMSEKPA 179

Query: 640  PLITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLE 819
            PL+TP  SEEDE+IIK+VV GK+PSYSLESKLGDCKRAA IR+EALQRITGKSLEGLPLE
Sbjct: 180  PLVTPAASEEDEEIIKSVVQGKMPSYSLESKLGDCKRAASIRKEALQRITGKSLEGLPLE 239

Query: 820  GFDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILA 999
            GFDY SILGQCCEMP+GYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI A
Sbjct: 240  GFDYESILGQCCEMPIGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIYA 299

Query: 1000 SGGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            SGGANSVLLRDGMTRAP VRFGTAKRAAELKF++ED
Sbjct: 300  SGGANSVLLRDGMTRAPCVRFGTAKRAAELKFFVED 335



 Score =  414 bits (1063), Expect(2) = 0.0
 Identities = 205/246 (83%), Positives = 227/246 (92%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RF CSTGDAMGMNMVSKGVQNVL++LQ +YPDMDV+GISGNFC+DKKPA
Sbjct: 359  QCAIAGKNLYMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEYPDMDVIGISGNFCSDKKPA 418

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 419  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 478

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+FIATGQDPAQN+ESS CITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQS
Sbjct: 479  NIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQS 538

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++++PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRS+KD
Sbjct: 539  ACLNLLGVKGANREAPGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSTKD 598

Query: 1853 ITNIAS 1870
            +T  +S
Sbjct: 599  VTKASS 604


>ref|XP_004232593.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 [Solanum
            lycopersicum]
          Length = 601

 Score =  443 bits (1140), Expect(2) = 0.0
 Identities = 230/335 (68%), Positives = 263/335 (78%), Gaps = 10/335 (2%)
 Frame = +1

Query: 133  MDSRRR--SPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSV 306
            MD RRR   P  T+K A+   PL     + QQ S P++SD LPLPLYL NG+FFT+FFSV
Sbjct: 1    MDVRRRPVKPLCTSKDASAGEPL-----KQQQVSSPKASDALPLPLYLTNGLFFTMFFSV 55

Query: 307  MYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNEGW 486
            MYFLL RWREKIRN+ PLHVVT             VIYL+ FFG+ FVQS + + N++ W
Sbjct: 56   MYFLLVRWREKIRNSIPLHVVTLSELLAMVSLIASVIYLLGFFGIGFVQSFVSRSNSDSW 115

Query: 487  EIEEE----ILMVEDSRNG--TNCTTLGCAVPPPSVPKIAPVVPQQPSKMVI--IEKPAP 642
            +IE+E    +++ EDSR G     TTLGC VPPP V KIAP+VPQQP+K  +   EKPAP
Sbjct: 116  DIEDENAEQLIIEEDSRRGPCAAATTLGCVVPPPPVRKIAPMVPQQPAKAALSQTEKPAP 175

Query: 643  LITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEG 822
            +I P  SE+DE+II++VV GK PSYSLESKLGDC RAA IR+EALQRITGKSLEGLPLEG
Sbjct: 176  IIMPALSEDDEEIIQSVVQGKTPSYSLESKLGDCMRAASIRKEALQRITGKSLEGLPLEG 235

Query: 823  FDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILAS 1002
            FDY SILGQCCEMPVGYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI  S
Sbjct: 236  FDYESILGQCCEMPVGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIFVS 295

Query: 1003 GGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            GGANS+LLRDGMTRAPVVRF TAKRAAELKF++ED
Sbjct: 296  GGANSILLRDGMTRAPVVRFTTAKRAAELKFFVED 330



 Score =  417 bits (1071), Expect(2) = 0.0
 Identities = 207/247 (83%), Positives = 230/247 (93%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RFSCSTGDAMGMNMVSKGVQNVL++LQ++YPDMDV+GISGNFC+DKKPA
Sbjct: 354  QCAIAGKNLYMRFSCSTGDAMGMNMVSKGVQNVLDYLQSEYPDMDVIGISGNFCSDKKPA 413

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAIIKE++VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 414  AVNWIEGRGKSVVCEAIIKEDVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 473

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+++ATGQDPAQNVESS CITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS
Sbjct: 474  NIVSAVYLATGQDPAQNVESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 533

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++D+PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRS KD
Sbjct: 534  ACLNLLGVKGANRDAPGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSIKD 593

Query: 1853 ITNIASS 1873
            I+ + +S
Sbjct: 594  ISQVINS 600


>gb|AAL54878.1|AF004232_1 hydroxy-methyl-glutaryl-coenzyme A reductase [Nicotiana tabacum]
          Length = 604

 Score =  448 bits (1153), Expect(2) = 0.0
 Identities = 235/336 (69%), Positives = 269/336 (80%), Gaps = 11/336 (3%)
 Frame = +1

Query: 133  MDSRRRSPTV---TAKAAAGELPLAPHEGQNQQP-SIPRSSDVLPLPLYLANGVFFTLFF 300
            MD RRRS      T + AAGE PL PH+ Q QQ  S+  +SD LPLPLYL NG+FFT+FF
Sbjct: 1    MDVRRRSEKPAYPTKEFAAGEKPLKPHKQQQQQDNSLLIASDALPLPLYLTNGLFFTMFF 60

Query: 301  SVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNE 480
            SVMY+LL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQS + + NN+
Sbjct: 61   SVMYYLLSRWREKIRNSTPLHVVTFSELVAIVSLIASVIYLLGFFGIGFVQSFVSRDNND 120

Query: 481  -GWEIEEE----ILMVEDSRNGTNCTTLGC-AVPPPSVPKIAPVVPQQPSKMVII-EKPA 639
              W++E+E     L+ EDSR G   TTLGC AVPPP   ++ P+VP QP+K+  + EKPA
Sbjct: 121  DSWDVEDENDEQFLLEEDSRRGP-ATTLGCTAVPPPPARQVVPMVPPQPAKVAAMSEKPA 179

Query: 640  PLITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLE 819
            PL+TP  SEEDE+IIK+VV GK+PSYSLESKLGDCKRAA IR+EALQRITGKSLEGLPLE
Sbjct: 180  PLVTPAASEEDEEIIKSVVQGKMPSYSLESKLGDCKRAASIRKEALQRITGKSLEGLPLE 239

Query: 820  GFDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILA 999
            GFDY SILGQCCEMP+GYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI A
Sbjct: 240  GFDYESILGQCCEMPIGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIYA 299

Query: 1000 SGGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            SGGA SVLLRDGMTRAP VRFGTAKRAAELKF++ED
Sbjct: 300  SGGATSVLLRDGMTRAPCVRFGTAKRAAELKFFVED 335



 Score =  411 bits (1056), Expect(2) = 0.0
 Identities = 204/246 (82%), Positives = 226/246 (91%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RF CSTGDAMGMNMVSKGVQNVL++LQ +YPDMDV+GISGNFC+DKKPA
Sbjct: 359  QCAIAGKNLYMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEYPDMDVIGISGNFCSDKKPA 418

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVAAL+E NM+KN            FNAHAS
Sbjct: 419  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVEPNMLKNLTGSAMAGALGGFNAHAS 478

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+FIATGQDPAQN+ESS CITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQS
Sbjct: 479  NIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQS 538

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++++PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRS+KD
Sbjct: 539  ACLNLLGVKGANREAPGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSTKD 598

Query: 1853 ITNIAS 1870
            +T  +S
Sbjct: 599  VTKASS 604


>sp|Q01559.1|HMDH_NICSY RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase;
            Short=HMG-CoA reductase gi|19746|emb|CAA45181.1|
            3-hydroxy-3-methylglutaryl-coenzyme A reductase
            [Nicotiana sylvestris]
          Length = 604

 Score =  446 bits (1147), Expect(2) = 0.0
 Identities = 237/336 (70%), Positives = 268/336 (79%), Gaps = 11/336 (3%)
 Frame = +1

Query: 133  MDSRRRSPTV---TAKAAAGELPLAPHEGQNQQP-SIPRSSDVLPLPLYLANGVFFTLFF 300
            MD RRRS      T + AAGE PL PH+ Q +Q  S+  +SD LPLPLYL NG+FFT+FF
Sbjct: 1    MDVRRRSEKPAYPTKEFAAGEKPLKPHKQQQEQDNSLLIASDALPLPLYLTNGLFFTMFF 60

Query: 301  SVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNN- 477
            SVMY+LL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQS + + NN 
Sbjct: 61   SVMYYLLSRWREKIRNSTPLHVVTFSELVAIASLIASVIYLLGFFGIGFVQSFVSRDNND 120

Query: 478  EGWEIEEE----ILMVEDSRNGTNCTTLGC-AVPPPSVPKIAPVVPQQPSKMVII-EKPA 639
            E W+ E+E     L+ EDSR G   TTLGC AVPPP   +I P+VP QPSK+  + EKPA
Sbjct: 121  ECWDEEDENDEQFLLEEDSRRGP-ATTLGCTAVPPPPALQIVPMVPPQPSKVAAMSEKPA 179

Query: 640  PLITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLE 819
            PL+TP  SEEDE+IIK+VV GK+PSYSLESKLGDCKRAA IR+EALQRITGKSLEGLPLE
Sbjct: 180  PLVTPAASEEDEEIIKSVVQGKMPSYSLESKLGDCKRAASIRKEALQRITGKSLEGLPLE 239

Query: 820  GFDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILA 999
            GFDY SILGQCCEMP+GYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI A
Sbjct: 240  GFDYESILGQCCEMPIGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIYA 299

Query: 1000 SGGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            SGGA SVLLRDGMTRAP VRFGTAKRAAELKF++ED
Sbjct: 300  SGGATSVLLRDGMTRAPCVRFGTAKRAAELKFFVED 335



 Score =  411 bits (1057), Expect(2) = 0.0
 Identities = 204/246 (82%), Positives = 226/246 (91%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RF CSTGDAMGMNMVSKGVQNVL++LQ +YPDMDV+GISGNFC+DKKPA
Sbjct: 359  QCAIAGKNLYMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEYPDMDVIGISGNFCSDKKPA 418

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 419  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 478

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA++IATGQDPAQN+ESS CITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQS
Sbjct: 479  NIVSAVYIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQS 538

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA+++ PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRS+KD
Sbjct: 539  ACLNLLGVKGANREVPGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSTKD 598

Query: 1853 ITNIAS 1870
            +T  +S
Sbjct: 599  VTKASS 604


>gb|AAB87727.1| hydroxy-methylglutaryl-coenzyme A reductase [Nicotiana tabacum]
          Length = 604

 Score =  446 bits (1148), Expect(2) = 0.0
 Identities = 233/337 (69%), Positives = 268/337 (79%), Gaps = 12/337 (3%)
 Frame = +1

Query: 133  MDSRRR--SPTVTAK--AAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFF 300
            MD RRR   P   +K   +AGE  L PH+ Q QQ S P++SD LPLPLYL NG+FFT+FF
Sbjct: 1    MDVRRRPVKPFYPSKDDVSAGE-SLKPHK-QTQQVSSPKASDALPLPLYLTNGLFFTMFF 58

Query: 301  SVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNE 480
            SVMYFLL RWREKIRN+TPLH+VT             VIYL+ FFG+ FVQS + + N++
Sbjct: 59   SVMYFLLVRWREKIRNSTPLHMVTLSELVAMVSLIASVIYLLGFFGIGFVQSFVSRSNSD 118

Query: 481  GWEIEEE----ILMVEDSRNG--TNCTTLGCAVPPPSVPKIAPVVPQQPSK--MVIIEKP 636
             W++E+E     ++ EDSR G     TTLGCAVPPPS  +I P+VPQQP+K  + + EKP
Sbjct: 119  SWDVEDENTEQFIIEEDSRRGPCAAATTLGCAVPPPSARQIVPMVPQQPAKVALAVAEKP 178

Query: 637  APLITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPL 816
            AP+ITP  SE+DE+II++VV GK PSYSLESKL DCKRAA +RREALQRITGKSLEGLPL
Sbjct: 179  APIITPAVSEDDEEIIQSVVQGKTPSYSLESKLADCKRAASVRREALQRITGKSLEGLPL 238

Query: 817  EGFDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAIL 996
            EGFDY SILGQCCEMPVGYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI 
Sbjct: 239  EGFDYESILGQCCEMPVGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIF 298

Query: 997  ASGGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            ASGGA SVLLRDGMTRAPVVRF TAKRAAELKF++ED
Sbjct: 299  ASGGAISVLLRDGMTRAPVVRFATAKRAAELKFFVED 335



 Score =  410 bits (1055), Expect(2) = 0.0
 Identities = 204/246 (82%), Positives = 228/246 (92%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RFSCSTGDAMGMNMVSKGVQNVL++LQ +YPDMDV+GISGNFC+DKKPA
Sbjct: 359  QCAIAGKNLYMRFSCSTGDAMGMNMVSKGVQNVLDYLQNEYPDMDVIGISGNFCSDKKPA 418

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVA+L+ELN++KN            FNAHAS
Sbjct: 419  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVASLVELNVLKNLTGSAMAGALGGFNAHAS 478

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+++ATGQDPAQNVESS CITM+EAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS
Sbjct: 479  NIVSAVYLATGQDPAQNVESSHCITMIEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 538

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++++ G+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRSSKD
Sbjct: 539  ACLNLLGVKGANREAAGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSSKD 598

Query: 1853 ITNIAS 1870
            +T I+S
Sbjct: 599  VTKISS 604


>ref|NP_001275084.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1-like [Solanum
            tuberosum] gi|370344588|gb|AEX26933.1|
            3-hydroxy-3-methylglutaryl coenzyme A reductase 1
            [Solanum tuberosum]
          Length = 601

 Score =  441 bits (1133), Expect(2) = 0.0
 Identities = 227/335 (67%), Positives = 264/335 (78%), Gaps = 10/335 (2%)
 Frame = +1

Query: 133  MDSRRR--SPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSV 306
            MD RRR   P  T+K A+   PL     + Q+ S P++SD LPLPLYL NG+FFT+FFSV
Sbjct: 1    MDVRRRPVKPLYTSKDASAGEPL-----KQQEVSSPKASDALPLPLYLTNGLFFTMFFSV 55

Query: 307  MYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNEGW 486
            MYFLL RWREKIRN+ PLHVVT             V+YL+ FFG+ FVQS + + N++ W
Sbjct: 56   MYFLLVRWREKIRNSIPLHVVTLSELLAMVSLIASVVYLLGFFGIGFVQSFVSRSNSDSW 115

Query: 487  EIEEE----ILMVEDSRNG--TNCTTLGCAVPPPSVPKIAPVVPQQPSKMVI--IEKPAP 642
            +IE+E    +++ EDSR G     TTLGC VPPP V KIAP+VPQQP+K+ +   EKP+P
Sbjct: 116  DIEDENAEQLIIEEDSRRGPCAAATTLGCVVPPPPVRKIAPMVPQQPAKVALSQTEKPSP 175

Query: 643  LITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEG 822
            +I P  SE+DE+II++VV GK PSYSLESKLGDC RAA IR+EALQRITGKSLEGLPLEG
Sbjct: 176  IIMPALSEDDEEIIQSVVQGKTPSYSLESKLGDCMRAASIRKEALQRITGKSLEGLPLEG 235

Query: 823  FDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILAS 1002
            FDY SILGQCCEMPVGYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI  S
Sbjct: 236  FDYESILGQCCEMPVGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIFVS 295

Query: 1003 GGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            GGA+SVLLRDGMTRAPVVRF TAKRAAELKF++ED
Sbjct: 296  GGADSVLLRDGMTRAPVVRFATAKRAAELKFFVED 330



 Score =  416 bits (1070), Expect(2) = 0.0
 Identities = 206/247 (83%), Positives = 230/247 (93%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RFSCSTGDAMGMNMVSKGVQNVL++LQ++YPDMDV+GISGNFC+DKKPA
Sbjct: 354  QCAIAGKNLYMRFSCSTGDAMGMNMVSKGVQNVLDYLQSEYPDMDVIGISGNFCSDKKPA 413

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAIIKEE+VK VLKTEVAAL+ELN++KN            FNAHAS
Sbjct: 414  AVNWIEGRGKSVVCEAIIKEEVVKKVLKTEVAALVELNLLKNLTGSAMAGALGGFNAHAS 473

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+++ATGQDPAQNVESS CITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQS
Sbjct: 474  NIVSAVYLATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQS 533

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++D+PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRS KD
Sbjct: 534  ACLNLLGVKGANRDAPGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSIKD 593

Query: 1853 ITNIASS 1873
            I+ + +S
Sbjct: 594  ISQVITS 600


>gb|AAL54879.1|AF004233_1 hydroxy-methyl-glutaryl-coenzyme A reductase [Nicotiana tabacum]
          Length = 604

 Score =  448 bits (1153), Expect(2) = 0.0
 Identities = 237/336 (70%), Positives = 269/336 (80%), Gaps = 11/336 (3%)
 Frame = +1

Query: 133  MDSRRRSPTV---TAKAAAGELPLAPHEGQNQQP-SIPRSSDVLPLPLYLANGVFFTLFF 300
            MD RRRS      T + AAGE PL PH+ Q +Q  S+  +SD LPLPLYL NG+FFT+FF
Sbjct: 1    MDVRRRSEKPAYPTKEFAAGEKPLKPHKQQQEQDNSLLIASDALPLPLYLTNGLFFTMFF 60

Query: 301  SVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNN- 477
            SVMY+LL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQS + + NN 
Sbjct: 61   SVMYYLLSRWREKIRNSTPLHVVTFSELVAIASLIASVIYLLGFFGIGFVQSFVSRDNND 120

Query: 478  EGWEIEEE----ILMVEDSRNGTNCTTLGC-AVPPPSVPKIAPVVPQQPSKMVII-EKPA 639
            E W++E+E     L+ EDSR G   TTLGC AVPPP   +I P+VP QPSK+  + EKPA
Sbjct: 121  ECWDVEDENDEQFLLEEDSRRGP-ATTLGCTAVPPPPALQIVPMVPPQPSKVAAMSEKPA 179

Query: 640  PLITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLE 819
            PL+TP  SEEDE+IIK+VV GK+PSYSLESKLGDCKRAA IR+EALQRITGKSLEGLPLE
Sbjct: 180  PLVTPAASEEDEEIIKSVVQGKMPSYSLESKLGDCKRAASIRKEALQRITGKSLEGLPLE 239

Query: 820  GFDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILA 999
            GFDY SILGQCCEMP+GYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI A
Sbjct: 240  GFDYESILGQCCEMPIGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIYA 299

Query: 1000 SGGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            SGGA SVLLRDGMTRAP VRFGTAKRAAELKF++ED
Sbjct: 300  SGGATSVLLRDGMTRAPCVRFGTAKRAAELKFFVED 335



 Score =  408 bits (1049), Expect(2) = 0.0
 Identities = 203/246 (82%), Positives = 225/246 (91%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RF CSTGDAMGMNMVSKGVQNVL++LQ +Y DMDV+GISGNFC+DKKPA
Sbjct: 359  QCAIAGKNLYMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEYSDMDVIGISGNFCSDKKPA 418

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 419  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 478

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA++IATGQDPAQN+ESS CITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQS
Sbjct: 479  NIVSAVYIATGQDPAQNIESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQS 538

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA+++ PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRS+KD
Sbjct: 539  ACLNLLGVKGANREVPGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSTKD 598

Query: 1853 ITNIAS 1870
            +T  +S
Sbjct: 599  VTKASS 604


>gb|AEX26934.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase 1 [Solanum chacoense]
          Length = 601

 Score =  442 bits (1137), Expect(2) = 0.0
 Identities = 229/335 (68%), Positives = 264/335 (78%), Gaps = 10/335 (2%)
 Frame = +1

Query: 133  MDSRRR--SPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSV 306
            MD RRR   P  T+K A+   PL     + Q+ S P++SD LPLPLYL NG+FFT+FFSV
Sbjct: 1    MDVRRRPVKPLYTSKDASAGEPL-----KQQEVSSPKASDALPLPLYLTNGLFFTMFFSV 55

Query: 307  MYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNEGW 486
            MYFLL RWREKIRN+ PLHVVT             VIYL+ FFG+ FVQS + + N++ W
Sbjct: 56   MYFLLVRWREKIRNSIPLHVVTLSELLAMVSLIASVIYLLGFFGIGFVQSFVSRSNSDSW 115

Query: 487  EIEEE----ILMVEDSRNG--TNCTTLGCAVPPPSVPKIAPVVPQQPSKMVI--IEKPAP 642
            +IE+E    +++ EDSR G     TTLGC VPPP V KIAP+VPQQP+K+ +   EKPAP
Sbjct: 116  DIEDENTEQLIIEEDSRRGPCAAATTLGCVVPPPPVRKIAPMVPQQPAKVALSQTEKPAP 175

Query: 643  LITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEG 822
            +I P  SE+DE+II++VV GK PSYSLESKLGDC RAA IR+EALQRITGKSLEGLPLEG
Sbjct: 176  MIMPALSEDDEEIIQSVVQGKTPSYSLESKLGDCMRAASIRKEALQRITGKSLEGLPLEG 235

Query: 823  FDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILAS 1002
            FDY SILGQCCEMPVGYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI  S
Sbjct: 236  FDYESILGQCCEMPVGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIFVS 295

Query: 1003 GGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            GGA+SVLLRDGMTRAPVVRF TAKRAAELKF++ED
Sbjct: 296  GGADSVLLRDGMTRAPVVRFSTAKRAAELKFFVED 330



 Score =  414 bits (1064), Expect(2) = 0.0
 Identities = 206/247 (83%), Positives = 229/247 (92%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RFSCSTGDAMGMNMVSKGVQNVL++LQ++ PDMDV+GISGNFC+DKKPA
Sbjct: 354  QCAIAGKNLYMRFSCSTGDAMGMNMVSKGVQNVLDYLQSECPDMDVIGISGNFCSDKKPA 413

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAIIKEE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 414  AVNWIEGRGKSVVCEAIIKEEVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 473

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+++ATGQDPAQNVESS CITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQS
Sbjct: 474  NIVSAVYLATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQS 533

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++D+PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRS KD
Sbjct: 534  ACLNLLGVKGANRDAPGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSIKD 593

Query: 1853 ITNIASS 1873
            I+ + +S
Sbjct: 594  ISQVITS 600


>ref|XP_006364832.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1-like
            [Solanum tuberosum]
          Length = 600

 Score =  438 bits (1126), Expect(2) = 0.0
 Identities = 227/335 (67%), Positives = 262/335 (78%), Gaps = 10/335 (2%)
 Frame = +1

Query: 133  MDSRRR--SPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSV 306
            MD RRR   P  T+K A+   PL       Q+ S P++SD LPLPLYL  G+FFT+FFSV
Sbjct: 1    MDVRRRPVKPLYTSKDASAGEPL------KQEVSSPKASDALPLPLYLTTGLFFTMFFSV 54

Query: 307  MYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNEGW 486
            MYFLL RWREKIRN+ PLHVVT             VIYL+ FFG+ FVQS + + N++ W
Sbjct: 55   MYFLLVRWREKIRNSIPLHVVTLSELLAMVSLIASVIYLLGFFGIGFVQSFVSRSNSDSW 114

Query: 487  EIEEE----ILMVEDSRNG--TNCTTLGCAVPPPSVPKIAPVVPQQPSKMVI--IEKPAP 642
            +IE+E    +++ EDSR G     TTLGC VPPP V KIAP+VPQQP+K+ +   EKP+P
Sbjct: 115  DIEDENAEQLIIEEDSRRGPCAAATTLGCVVPPPPVRKIAPMVPQQPAKVALSQTEKPSP 174

Query: 643  LITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEG 822
            +I P  SE+DE+II++VV GK PSYSLESKLGDC RAA IR+EALQRITGKSLEGLPLEG
Sbjct: 175  IIMPALSEDDEEIIQSVVQGKTPSYSLESKLGDCMRAASIRKEALQRITGKSLEGLPLEG 234

Query: 823  FDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILAS 1002
            FDY SILGQCCEMPVGYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI  S
Sbjct: 235  FDYESILGQCCEMPVGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIFVS 294

Query: 1003 GGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            GGA+SVLLRDGMTRAPVVRF TAKRAAELKF++ED
Sbjct: 295  GGADSVLLRDGMTRAPVVRFSTAKRAAELKFFVED 329



 Score =  417 bits (1073), Expect(2) = 0.0
 Identities = 207/247 (83%), Positives = 230/247 (93%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RFSCSTGDAMGMNMVSKGVQNVL++LQ++YPDMDV+GISGNFC+DKKPA
Sbjct: 353  QCAIAGKNLYMRFSCSTGDAMGMNMVSKGVQNVLDYLQSEYPDMDVIGISGNFCSDKKPA 412

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAIIKEE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 413  AVNWIEGRGKSVVCEAIIKEEVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 472

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+++ATGQDPAQNVESS CITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQS
Sbjct: 473  NIVSAVYLATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQS 532

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++D+PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRS KD
Sbjct: 533  ACLNLLGVKGANRDAPGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSIKD 592

Query: 1853 ITNIASS 1873
            I+ + +S
Sbjct: 593  ISQVITS 599


>ref|NP_001275461.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 [Solanum tuberosum]
            gi|1346297|sp|P48020.1|HMDH1_SOLTU RecName:
            Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase 1;
            Short=HMG-CoA reductase 1; Short=HMGR; Short=HMGR1
            gi|169485|gb|AAA93498.1| hydroxymethylglutaryl coenzyme A
            reductase [Solanum tuberosum]
          Length = 596

 Score =  441 bits (1134), Expect(2) = 0.0
 Identities = 228/335 (68%), Positives = 265/335 (79%), Gaps = 10/335 (2%)
 Frame = +1

Query: 133  MDSRRR--SPTVTAKAAAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFSV 306
            MD RRR   P  T+K A+   PL     + Q+ S P++SD LPLPLYL NG+FFT+FFSV
Sbjct: 1    MDVRRRPVKPLYTSKDASAGEPL-----KQQEVSSPKASDALPLPLYLTNGLFFTMFFSV 55

Query: 307  MYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNEGW 486
            MYFLL RWREKIRN+ PLHVVT             VIYL+ FFG+ FVQS + + N++ W
Sbjct: 56   MYFLLVRWREKIRNSIPLHVVTLSELLAMVSLIASVIYLLGFFGIGFVQSFVSRSNSDSW 115

Query: 487  EIEEE----ILMVEDSRNG--TNCTTLGCAVPPPSVPKIAPVVPQQPSKMVI--IEKPAP 642
            +IE+E    +++ EDSR G     TTLGC VPPP V KIAP+VPQQP+K+ +   EKP+P
Sbjct: 116  DIEDENAEQLIIEEDSRRGPCAAATTLGCVVPPPPVRKIAPMVPQQPAKVALSQTEKPSP 175

Query: 643  LITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEG 822
            +I P  SE+DE+II++VV GK PSYSLESKLGDC RAA IR+EALQRITGKSLEGLPLEG
Sbjct: 176  IIMPALSEDDEEIIQSVVQGKTPSYSLESKLGDCMRAASIRKEALQRITGKSLEGLPLEG 235

Query: 823  FDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILAS 1002
            FDY+SILGQCCEMPVGYVQ+PVGIAGPLLLDGREY +PMATTEGCLVASTNRGCKAI  S
Sbjct: 236  FDYSSILGQCCEMPVGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIFVS 295

Query: 1003 GGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            GGA+SVLLRDGMTRAPVVRF TAKRAAELKF++ED
Sbjct: 296  GGADSVLLRDGMTRAPVVRFTTAKRAAELKFFVED 330



 Score =  414 bits (1063), Expect(2) = 0.0
 Identities = 206/242 (85%), Positives = 226/242 (93%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLYI FSCSTGDAMGMNMVSKGVQNVL++LQ++YPDMDV+GISGNFC+DKKPA
Sbjct: 354  QCAIAGKNLYITFSCSTGDAMGMNMVSKGVQNVLDYLQSEYPDMDVIGISGNFCSDKKPA 413

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAIIKEE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 414  AVNWIEGRGKSVVCEAIIKEEVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 473

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+++ATGQDPAQNVESS CITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQS
Sbjct: 474  NIVSAVYLATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQS 533

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++D+PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRS KD
Sbjct: 534  ACLNLLGVKGANRDAPGSNARLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSIKD 593

Query: 1853 IT 1858
            I+
Sbjct: 594  IS 595


>ref|XP_004231636.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2-like
            [Solanum lycopersicum] gi|2246450|gb|AAB62581.1|
            3-hydroxy-3-methylglutaryl CoA reductase 2 [Solanum
            lycopersicum]
          Length = 601

 Score =  438 bits (1127), Expect(2) = 0.0
 Identities = 229/334 (68%), Positives = 264/334 (79%), Gaps = 9/334 (2%)
 Frame = +1

Query: 133  MDSRRRS--PTVTAKA-AAGELPLAPHEGQNQQPS-----IPRSSDVLPLPLYLANGVFF 288
            MD RRRS  P   +K  AA E PL PH+ Q QQ       +  +SD LPLPLYL NG+FF
Sbjct: 1    MDVRRRSEEPVYPSKVFAADEKPLKPHKKQQQQQEDKNTLLIDASDALPLPLYLTNGLFF 60

Query: 289  TLFFSVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYK 468
            T+FFSVMYFLL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQ+ + +
Sbjct: 61   TMFFSVMYFLLSRWREKIRNSTPLHVVTLSELGAIVSLIASVIYLLGFFGIGFVQTFVSR 120

Query: 469  PNNEGW-EIEEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPL 645
             NN+ W E +EE L+ EDSR G   TTLGCAVP P   +IAP+ P QPS M ++EKPAPL
Sbjct: 121  GNNDSWDENDEEFLLKEDSRCGP-ATTLGCAVPAPPARQIAPMAPPQPS-MSMVEKPAPL 178

Query: 646  ITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGF 825
            IT  +SEEDE+IIK+VV GKIPSYSLESKLGDCKRAA IR+E +QRITGKSLEGLPLEGF
Sbjct: 179  ITSASSEEDEEIIKSVVQGKIPSYSLESKLGDCKRAASIRKEVMQRITGKSLEGLPLEGF 238

Query: 826  DYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASG 1005
            +Y SILGQCCEMP+GYVQ+PVGIAGPLLL+G+E+ +PMATTEGCLVASTNRGCKAI ASG
Sbjct: 239  NYESILGQCCEMPIGYVQIPVGIAGPLLLNGKEFSVPMATTEGCLVASTNRGCKAIYASG 298

Query: 1006 GANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            GA  +LLRDGMTRAP VRFGTAKRAAELKF++ED
Sbjct: 299  GATCILLRDGMTRAPCVRFGTAKRAAELKFFVED 332



 Score =  412 bits (1058), Expect(2) = 0.0
 Identities = 204/246 (82%), Positives = 226/246 (91%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RF CSTGDAMGMNMVSKGVQNVL++LQ +YPDMDV+GISGNFC+DKKPA
Sbjct: 356  QCAIAGKNLYMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEYPDMDVIGISGNFCSDKKPA 415

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 416  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 475

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+FIATGQDPAQN+ESS CITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS
Sbjct: 476  NIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 535

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++++PG+N+RLLAT+VAGSVLAGELSLMSAIS+GQLV SHMKYNRS+KD
Sbjct: 536  ACLNLLGVKGANREAPGSNARLLATVVAGSVLAGELSLMSAISSGQLVNSHMKYNRSTKD 595

Query: 1853 ITNIAS 1870
            +T  +S
Sbjct: 596  VTKASS 601


>dbj|BAB20771.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase [Solanum tuberosum]
          Length = 595

 Score =  438 bits (1127), Expect(2) = 0.0
 Identities = 225/332 (67%), Positives = 266/332 (80%), Gaps = 7/332 (2%)
 Frame = +1

Query: 133  MDSRRRS--PTVTAKA-AAGELPLAPHEGQNQQPS---IPRSSDVLPLPLYLANGVFFTL 294
            MD RRRS  P   +K  AA E PL PH+ Q Q+ +   +  +SD LPLPLYL NG+FFT+
Sbjct: 1    MDVRRRSEKPVYPSKVFAADEKPLKPHKNQQQEDNNTLLIDASDALPLPLYLTNGLFFTM 60

Query: 295  FFSVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPN 474
            FFSVMYFLL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQ+ + + N
Sbjct: 61   FFSVMYFLLSRWREKIRNSTPLHVVTLSELGAIVSLIASVIYLLGFFGIGFVQTFVSRGN 120

Query: 475  NEGW-EIEEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLIT 651
            N+ W E +EE L+ EDSR G   TTLGCA+P P   +I+P+ P QP+ M ++EKP+PLIT
Sbjct: 121  NDSWDENDEEFLLKEDSRCGP-ATTLGCAIPAPPARQISPMAPPQPA-MSMVEKPSPLIT 178

Query: 652  PQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDY 831
            P +SEEDE+IIK+VV GKIPSYSLESKLGDCKRAA IR+E +QRITGKSLEGLPLEGF+Y
Sbjct: 179  PASSEEDEEIIKSVVQGKIPSYSLESKLGDCKRAASIRKEVMQRITGKSLEGLPLEGFNY 238

Query: 832  ASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGA 1011
             SILGQCCEMP+GYVQ+PVGIAGPLLL+G+E+ +PMATTEGCLVASTNRGCKAI ASGGA
Sbjct: 239  ESILGQCCEMPIGYVQIPVGIAGPLLLNGKEFSVPMATTEGCLVASTNRGCKAIYASGGA 298

Query: 1012 NSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
              +LLRDGMTRAP VRFGTAKRAAELKF++ED
Sbjct: 299  TCILLRDGMTRAPCVRFGTAKRAAELKFFVED 330



 Score =  406 bits (1043), Expect(2) = 0.0
 Identities = 202/239 (84%), Positives = 221/239 (92%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RF CSTGDAMGMNMVSKGVQNVL++LQ +YPDMDV+GISGNFC+DKKPA
Sbjct: 354  QCAIAGKNLYMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEYPDMDVIGISGNFCSDKKPA 413

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 414  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 473

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+FIATGQDPAQN+ESS CITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS
Sbjct: 474  NIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 533

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSK 1849
            ACLNLLGVKGA++++PG+N+RLLAT+VAGSVLAGELSLMSAISAGQLV SHMKYNRS+K
Sbjct: 534  ACLNLLGVKGANREAPGSNARLLATVVAGSVLAGELSLMSAISAGQLVNSHMKYNRSTK 592


>ref|XP_006350440.1| PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 [Solanum
            tuberosum]
          Length = 596

 Score =  432 bits (1112), Expect(2) = 0.0
 Identities = 226/332 (68%), Positives = 264/332 (79%), Gaps = 7/332 (2%)
 Frame = +1

Query: 133  MDSRRRS--PTVTAKA-AAGELPLAPHEGQNQQPS---IPRSSDVLPLPLYLANGVFFTL 294
            MD RRRS  P   +K  AA E PL PH+ Q Q+ +   +  +SD LPLPLYL NG+FFT+
Sbjct: 1    MDVRRRSEKPVYPSKVFAADEKPLKPHKNQQQEDNNTLLIDASDALPLPLYLTNGLFFTM 60

Query: 295  FFSVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPN 474
            FFSVMYFLL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQ+ + + N
Sbjct: 61   FFSVMYFLLSRWREKIRNSTPLHVVTLSELGAIVSLIASVIYLLGFFGIGFVQTFVSRGN 120

Query: 475  NEGW-EIEEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLIT 651
            N+ W E +EE L+ EDSR G   TTLGCA+P     +IAP+ P QP+ M + EKPAPLIT
Sbjct: 121  NDSWDENDEEFLLKEDSRCGP-ATTLGCAIP---ARQIAPMAPPQPA-MSVAEKPAPLIT 175

Query: 652  PQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDY 831
            P +SEEDE+IIK+VV GKIPSYSLESKLGDCKRAA IR+E +QRITGKSLEGLPLEGF+Y
Sbjct: 176  PASSEEDEEIIKSVVQGKIPSYSLESKLGDCKRAASIRKEVMQRITGKSLEGLPLEGFNY 235

Query: 832  ASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGA 1011
             SILGQCCEMP+GYVQ+PVGIAGPLLL+G+E+ +PMATTEGCLVASTNRGCKAI ASGGA
Sbjct: 236  ESILGQCCEMPIGYVQIPVGIAGPLLLNGKEFSVPMATTEGCLVASTNRGCKAIYASGGA 295

Query: 1012 NSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
              +LLRDGMTRAP VRFGTAKRAAELKF++ED
Sbjct: 296  TCILLRDGMTRAPCVRFGTAKRAAELKFFVED 327



 Score =  410 bits (1055), Expect(2) = 0.0
 Identities = 203/246 (82%), Positives = 226/246 (91%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RF CSTGDAMGMNMVSKGVQNVL++LQ +YPDMDV+GISGNFC+DKKP+
Sbjct: 351  QCAIAGKNLYMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEYPDMDVIGISGNFCSDKKPS 410

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVA+L+ELNM+KN            FNAHAS
Sbjct: 411  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVASLVELNMLKNLTGSAMAGALGGFNAHAS 470

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+FIATGQDPAQN+ESS CITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS
Sbjct: 471  NIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 530

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++++PG+N+RLLAT+VAGSVLAGELSLMSAISAGQLV SHMKYNRS+KD
Sbjct: 531  ACLNLLGVKGANREAPGSNARLLATVVAGSVLAGELSLMSAISAGQLVNSHMKYNRSTKD 590

Query: 1853 ITNIAS 1870
            +T  +S
Sbjct: 591  VTKASS 596


>sp|Q9XEL8.1|HMDH2_CAPAN RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase 2;
            Short=HMG-CoA reductase 2
            gi|4704615|gb|AAD28179.1|AF110383_1
            3-hydroxy-3-methylglutaryl-coenzyme A reductase [Capsicum
            annuum]
          Length = 604

 Score =  436 bits (1121), Expect(2) = 0.0
 Identities = 225/336 (66%), Positives = 262/336 (77%), Gaps = 11/336 (3%)
 Frame = +1

Query: 133  MDSRRRSPTVTAKA---AAGELPLAPHEGQNQQPS--IPRSSDVLPLPLYLANGVFFTLF 297
            MD RRRS      +   AA E PL PH+ Q ++ +  +  +SD LPLPLY  NG+FFT+F
Sbjct: 1    MDVRRRSEEAVYSSKVFAADEKPLKPHKQQQEEDNTLLIDASDALPLPLYFTNGLFFTMF 60

Query: 298  FSVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNN 477
            FSVMYFLL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQ+ + + NN
Sbjct: 61   FSVMYFLLSRWREKIRNSTPLHVVTLSELGAIVSLIASVIYLLGFFGIGFVQTFVARGNN 120

Query: 478  EGWEIEEE----ILMVEDSRNG--TNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPA 639
            + W+ E+E     ++ EDSR G     TTLGCAVP P    IAP+VPQQP+ + I EKPA
Sbjct: 121  DSWDEEDENDEQFILEEDSRRGPCAAATTLGCAVPTPPAKHIAPIVPQQPA-VSIAEKPA 179

Query: 640  PLITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLE 819
            PL+TP  SEEDE+IIK+VV GKIPSYSLESKLGDCKRAA IR+E LQRITGKSLEGLPL+
Sbjct: 180  PLVTPAASEEDEEIIKSVVQGKIPSYSLESKLGDCKRAASIRKEVLQRITGKSLEGLPLD 239

Query: 820  GFDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILA 999
            GF+Y SILGQCCEM +GYVQ+PVGIAGPLLL+GREY +PMATTEGCLVASTNRGCKAI A
Sbjct: 240  GFNYESILGQCCEMTIGYVQIPVGIAGPLLLNGREYSVPMATTEGCLVASTNRGCKAIYA 299

Query: 1000 SGGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            SGGA S+LLRDGMTRAP VRFGTAKRAAELKF++ED
Sbjct: 300  SGGATSILLRDGMTRAPCVRFGTAKRAAELKFFVED 335



 Score =  405 bits (1040), Expect(2) = 0.0
 Identities = 202/246 (82%), Positives = 224/246 (91%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNL++RF CSTGDAMGMNMVSKGVQNVL++LQ +Y DMDV+GIS NFC+DKKPA
Sbjct: 359  QCAIAGKNLHMRFVCSTGDAMGMNMVSKGVQNVLDYLQNEYADMDVIGISANFCSDKKPA 418

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 419  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVELNMLKNLTGSALAGALGGFNAHAS 478

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA++IATGQDPAQN+ESS CITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS
Sbjct: 479  NIVSAVYIATGQDPAQNIESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 538

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++++PG+N+RLLATIVAGSVLAGELSLMSAISAGQLV SHMKYNRS+KD
Sbjct: 539  ACLNLLGVKGANREAPGSNARLLATIVAGSVLAGELSLMSAISAGQLVNSHMKYNRSTKD 598

Query: 1853 ITNIAS 1870
            +T  +S
Sbjct: 599  VTKASS 604


>sp|P48022.1|HMDH2_SOLLC RecName: Full=3-hydroxy-3-methylglutaryl-coenzyme A reductase 2;
            Short=HMG-CoA reductase 2 gi|170452|gb|AAA34169.1|
            3-hydroxy-3-methylglutaryl coenzyme A reductase [Solanum
            lycopersicum]
          Length = 602

 Score =  431 bits (1108), Expect(2) = 0.0
 Identities = 228/335 (68%), Positives = 263/335 (78%), Gaps = 10/335 (2%)
 Frame = +1

Query: 133  MDSRRRS--PTVTAKA-AAGELPLAPHEGQNQQPS-----IPRSSDVLPLPLYLA-NGVF 285
            MD RRRS  P   +K  AA E PL PH+ Q QQ       +  +SD LPLPLYL  NG+F
Sbjct: 1    MDVRRRSEEPVYPSKVFAADEKPLKPHKKQQQQQEDKNTLLIDASDALPLPLYLTTNGLF 60

Query: 286  FTLFFSVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIY 465
            FT+FFSVMYFLL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQ+ + 
Sbjct: 61   FTMFFSVMYFLLSRWREKIRNSTPLHVVTLSELGAIVSLIASVIYLLGFFGIGFVQTFVS 120

Query: 466  KPNNEGW-EIEEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAP 642
            + NN+ W E +EE L+ EDSR G   TTLGCAVP P   +IAP+ P QPS M ++EKPAP
Sbjct: 121  RGNNDSWDENDEEFLLKEDSRCGP-ATTLGCAVPAPPARQIAPMAPPQPS-MSMVEKPAP 178

Query: 643  LITPQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEG 822
            LIT  +S EDE+IIK+VV GKIPSYSLESKLGDCKRAA IR+E +QRITGKSLEGLPLEG
Sbjct: 179  LITSASSGEDEEIIKSVVQGKIPSYSLESKLGDCKRAASIRKEVMQRITGKSLEGLPLEG 238

Query: 823  FDYASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILAS 1002
            F+Y SILGQCCEMP+GYVQ+PVGIAGPLLL+G+E+ +PMATTEGCLVASTNRGCKAI AS
Sbjct: 239  FNYESILGQCCEMPIGYVQIPVGIAGPLLLNGKEFSVPMATTEGCLVASTNRGCKAIYAS 298

Query: 1003 GGANSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            GGA  +LLRDGMTRAP VRFGTAKRAAELKF++ED
Sbjct: 299  GGATCILLRDGMTRAPCVRFGTAKRAAELKFFVED 333



 Score =  410 bits (1053), Expect(2) = 0.0
 Identities = 203/246 (82%), Positives = 225/246 (91%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+R  CSTGDAMGMNMVSKGVQNVL++LQ +YPDMDV+GISGNFC+DKKPA
Sbjct: 357  QCAIAGKNLYMRLCCSTGDAMGMNMVSKGVQNVLDYLQNEYPDMDVIGISGNFCSDKKPA 416

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 417  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 476

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA+FIATGQDPAQN+ESS CITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS
Sbjct: 477  NIVSAVFIATGQDPAQNIESSHCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 536

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++++PG+N+RLLAT+VAGSVLAGELSLMSAIS+GQLV SHMKYNRS+KD
Sbjct: 537  ACLNLLGVKGANREAPGSNARLLATVVAGSVLAGELSLMSAISSGQLVNSHMKYNRSTKD 596

Query: 1853 ITNIAS 1870
            +T  +S
Sbjct: 597  VTKASS 602


>gb|ADN39417.1| 3-hydroxy-3-methylglutaryl-coenzyme A reductase [Withania somnifera]
          Length = 599

 Score =  434 bits (1116), Expect(2) = 0.0
 Identities = 220/332 (66%), Positives = 260/332 (78%), Gaps = 7/332 (2%)
 Frame = +1

Query: 133  MDSRRRSPTVTAKA---AAGELPLAPHEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFFS 303
            MD RRRS      +   AA E PL PH+ Q     +  +SD LPLPLYL NG+FFT+FFS
Sbjct: 1    MDVRRRSEKAVYPSEVFAADEKPLKPHKQQEDNTLLIDASDALPLPLYLTNGLFFTMFFS 60

Query: 304  VMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNEG 483
            VMYFLL+RWREKIRN+TPLHVVT             VIYL+ FFG+ FVQ+ + + NN+ 
Sbjct: 61   VMYFLLSRWREKIRNSTPLHVVTLSELGAIVLLIASVIYLLGFFGIGFVQTFVSRVNNDS 120

Query: 484  WEIEEE----ILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLIT 651
            W++E+E     ++ EDSR  T  TTLGCA+P P   +IAP+VP QP+ M + EKPA L+T
Sbjct: 121  WDVEDENDEQFILEEDSRR-TPATTLGCAIPAPPARQIAPLVPPQPA-MSMAEKPAQLVT 178

Query: 652  PQNSEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDY 831
            P  SEEDE+IIK+VV G IPSYSLESKLGDCKRAA IR+EA+QR+TGKSLEGLPLEGF+Y
Sbjct: 179  PAASEEDEEIIKSVVQGTIPSYSLESKLGDCKRAASIRKEAVQRLTGKSLEGLPLEGFNY 238

Query: 832  ASILGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGA 1011
             SILGQCCEMP+GYVQ+PVG+AGPLLL+GREY +PMATTEGCLVASTNRGCKAI ASGGA
Sbjct: 239  ESILGQCCEMPIGYVQIPVGVAGPLLLNGREYSVPMATTEGCLVASTNRGCKAIYASGGA 298

Query: 1012 NSVLLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
              +LLRDGMTRAP VRFGT+KRAAELKF++ED
Sbjct: 299  TCILLRDGMTRAPCVRFGTSKRAAELKFFVED 330



 Score =  404 bits (1039), Expect(2) = 0.0
 Identities = 200/246 (81%), Positives = 223/246 (90%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RF CSTGDAMGMNM SKGVQNVL++LQ +YPDMDV+GISGNFC+DKKPA
Sbjct: 354  QCAIAGKNLYMRFVCSTGDAMGMNMASKGVQNVLDYLQNEYPDMDVIGISGNFCSDKKPA 413

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAII EE+VK VLKTEVA L+ELNM+KN            FNAHAS
Sbjct: 414  AVNWIEGRGKSVVCEAIITEEVVKKVLKTEVATLVELNMLKNLTGSAMAGALGGFNAHAS 473

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSA++IATGQDPAQN+ESS CITMMEAVN GKDLHISVTMPSIEVGTVGGGTQLASQS
Sbjct: 474  NIVSAVYIATGQDPAQNIESSHCITMMEAVNGGKDLHISVTMPSIEVGTVGGGTQLASQS 533

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGA++++PG+N+RLLATIVAGSVLAGELS+MSAISAG LV+SHMKYNRS+KD
Sbjct: 534  ACLNLLGVKGANREAPGSNARLLATIVAGSVLAGELSIMSAISAGHLVKSHMKYNRSAKD 593

Query: 1853 ITNIAS 1870
            +T  +S
Sbjct: 594  VTKASS 599


>dbj|BAE92730.1| 3-hydroxy-3-methylglutaryl coenzyme A reductase [Gentiana lutea]
          Length = 586

 Score =  418 bits (1075), Expect(2) = 0.0
 Identities = 210/244 (86%), Positives = 228/244 (93%)
 Frame = +2

Query: 1133 QCAIAGKNLYIRFSCSTGDAMGMNMVSKGVQNVLEFLQTDYPDMDVLGISGNFCADKKPA 1312
            QCAIAGKNLY+RF+CSTGDAMGMNMVSKGVQNVL+FLQ+D+PDMDV+GISGNFCADKKP+
Sbjct: 339  QCAIAGKNLYMRFTCSTGDAMGMNMVSKGVQNVLDFLQSDFPDMDVIGISGNFCADKKPS 398

Query: 1313 AVNWIEGRGKSVVCEAIIKEEIVKTVLKTEVAALIELNMVKNXXXXXXXXXXXXFNAHAS 1492
            AVNWIEGRGKSVVCEAIIKEEIVK VLKTEVAAL+ELNM+KN            FNAHAS
Sbjct: 399  AVNWIEGRGKSVVCEAIIKEEIVKKVLKTEVAALVELNMLKNLTGSAMAGALGGFNAHAS 458

Query: 1493 NIVSAIFIATGQDPAQNVESSQCITMMEAVNDGKDLHISVTMPSIEVGTVGGGTQLASQS 1672
            NIVSAI+IATGQDPAQNVESS CITMMEAVNDGKDLH+SVTMPSIEVGTVGGGTQLASQ+
Sbjct: 459  NIVSAIYIATGQDPAQNVESSHCITMMEAVNDGKDLHVSVTMPSIEVGTVGGGTQLASQA 518

Query: 1673 ACLNLLGVKGASKDSPGANSRLLATIVAGSVLAGELSLMSAISAGQLVRSHMKYNRSSKD 1852
            ACLNLLGVKGASK++ GANSRLLATIVAGSVLAGELSLMSAISAGQLV+SHMKYNRSS+D
Sbjct: 519  ACLNLLGVKGASKETAGANSRLLATIVAGSVLAGELSLMSAISAGQLVKSHMKYNRSSRD 578

Query: 1853 ITNI 1864
            +T +
Sbjct: 579  VTQL 582



 Score =  409 bits (1052), Expect(2) = 0.0
 Identities = 220/329 (66%), Positives = 252/329 (76%), Gaps = 4/329 (1%)
 Frame = +1

Query: 133  MDSRRRS-PTVTAKAAAGELPLAP---HEGQNQQPSIPRSSDVLPLPLYLANGVFFTLFF 300
            MD RRR        AAAGEL L P    + Q+ Q    ++SD LP PLYLANG+FFT+FF
Sbjct: 1    MDVRRRPLMPKPINAAAGELLLKPPSNQKNQSTQQQQVKASDALPFPLYLANGLFFTMFF 60

Query: 301  SVMYFLLTRWREKIRNATPLHVVTXXXXXXXXXXXXXVIYLVSFFGLDFVQSLIYKPNNE 480
            SV+YFLL RWR KIR++TPLHVVT             VIYLV FFG+DFVQSLIYKPN++
Sbjct: 61   SVIYFLLLRWRGKIRDSTPLHVVTLSELVAMISLIASVIYLVGFFGIDFVQSLIYKPNHD 120

Query: 481  GWEIEEEILMVEDSRNGTNCTTLGCAVPPPSVPKIAPVVPQQPSKMVIIEKPAPLITPQN 660
             W++E+E           N   L    P  +VP   P +P + +   +  KPAPLIT Q+
Sbjct: 121  VWDVEDE----------QNEQFL--VQPAKTVPSFPPPLPSEFAAEKV--KPAPLITHQD 166

Query: 661  SEEDEDIIKAVVAGKIPSYSLESKLGDCKRAAGIRREALQRITGKSLEGLPLEGFDYASI 840
            S+EDE+II++VV+GK PSYSLESKLGDCKRAA IRREALQRITGKSLEGLPLEGFDY SI
Sbjct: 167  SQEDEEIIESVVSGKTPSYSLESKLGDCKRAAKIRREALQRITGKSLEGLPLEGFDYESI 226

Query: 841  LGQCCEMPVGYVQLPVGIAGPLLLDGREYMLPMATTEGCLVASTNRGCKAILASGGANSV 1020
            LGQCCEMPVGYVQLPVGIAGPLLLDGREYM+PMATTEGCLVASTNRGCKA++A GGA SV
Sbjct: 227  LGQCCEMPVGYVQLPVGIAGPLLLDGREYMVPMATTEGCLVASTNRGCKAMVACGGATSV 286

Query: 1021 LLRDGMTRAPVVRFGTAKRAAELKFYMED 1107
            LL+DGMTRAPVVRFGTAKRAAELKF++ED
Sbjct: 287  LLKDGMTRAPVVRFGTAKRAAELKFFVED 315