BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Catharanthus23_contig00003560
         (1990 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gb|AGX93062.1| CYP72A224 7-deoxyloganic acid 7-hydroxylase [Cath...  1051   0.0  
gb|AGX93059.1| 7-deoxyloganic acid 7-hydroxylase-like protein [R...   978   0.0  
gb|AGX93058.1| 7-deoxyloganic acid 7-hydroxylase-like protein [A...   970   0.0  
gb|AGX93060.1| 7-deoxyloganic acid 7-hydroxylase-like protein [T...   967   0.0  
gb|AGX93061.1| 7-deoxyloganic acid 7-hydroxylase-like protein [V...   956   0.0  
gb|AGX93057.1| 7-deoxyloganic acid 7-hydroxylase-like protein [C...   951   0.0  
gb|AGX93056.1| 7-deoxyloganic acid 7-hydroxylase-like protein [L...   809   0.0  
gb|ADU19849.1| putative secologanin synthase [Camptotheca acumin...   639   e-180
dbj|BAL45198.1| cytochrome P450 monooxygenase [Medicago truncatula]   629   e-177
gb|ABC59078.1| cytochrome P450 monooxygenase CYP72A59 [Medicago ...   626   e-176
gb|EXB52089.1| Secologanin synthase [Morus notabilis]                 624   e-176
ref|XP_004488668.1| PREDICTED: secologanin synthase-like [Cicer ...   623   e-176
gb|EXB52087.1| Secologanin synthase [Morus notabilis]                 619   e-174
ref|XP_002333744.1| cytochrome P450 [Populus trichocarpa]             619   e-174
gb|AGX93064.1| secologanin synthase [Catharanthus roseus]             618   e-174
ref|XP_002331333.1| cytochrome P450 [Populus trichocarpa]             618   e-174
ref|XP_006477948.1| PREDICTED: secologanin synthase-like [Citrus...   617   e-174
ref|XP_006477946.1| PREDICTED: secologanin synthase-like [Citrus...   617   e-174
gb|AGX93046.1| secologanin synthase-like protein [Amsonia hubric...   616   e-173
sp|Q05047.1|C72A1_CATRO RecName: Full=Secologanin synthase; Shor...   616   e-173

>gb|AGX93062.1| CYP72A224 7-deoxyloganic acid 7-hydroxylase [Catharanthus roseus]
          Length = 521

 Score = 1051 bits (2718), Expect = 0.0
 Identities = 520/521 (99%), Positives = 520/521 (99%)
 Frame = -2

Query: 1797 MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG 1618
            MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG
Sbjct: 1    MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG 60

Query: 1617 KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK 1438
            KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK
Sbjct: 61   KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK 120

Query: 1437 YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 1258
            YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM
Sbjct: 121  YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 180

Query: 1257 VTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVI 1078
            VTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVI
Sbjct: 181  VTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVI 240

Query: 1077 RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLEC 898
            RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLEC
Sbjct: 241  RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLEC 300

Query: 897  NLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE 718
            NLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE
Sbjct: 301  NLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE 360

Query: 717  VFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLM 538
            VFQVFG KTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLM
Sbjct: 361  VFQVFGNKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLM 420

Query: 537  MPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK 358
            MPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK
Sbjct: 421  MPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK 480

Query: 357  MAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            MAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL
Sbjct: 481  MAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 521


>gb|AGX93059.1| 7-deoxyloganic acid 7-hydroxylase-like protein [Rauvolfia serpentina]
          Length = 520

 Score =  978 bits (2528), Expect = 0.0
 Identities = 480/521 (92%), Positives = 500/521 (95%)
 Frame = -2

Query: 1797 MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG 1618
            ME++FKS+  L FV L LYWVYR+LDW+WF+PKKLEKCLREQGFKGNPYRLFLGDQY+SG
Sbjct: 1    MEVSFKSVTVLGFVGLALYWVYRVLDWIWFRPKKLEKCLREQGFKGNPYRLFLGDQYESG 60

Query: 1617 KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK 1438
            KLI++A++KPIGVEEDVKKRIVPHILKTV THGK SFMWVGRIPRV ITDPELIKEVLTK
Sbjct: 61   KLIKEAMSKPIGVEEDVKKRIVPHILKTVETHGKNSFMWVGRIPRVQITDPELIKEVLTK 120

Query: 1437 YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 1258
            YYKFQKNHHDLDPITK LLTGIGSLEG+ WAKRRKIINAAFHFEKLKLMLPAFYLSCRDM
Sbjct: 121  YYKFQKNHHDLDPITKFLLTGIGSLEGETWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 180

Query: 1257 VTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVI 1078
            V KWD KVPEGGSAEVDVWHDIETLTGDVISRTLFGSN+ EGRRIFELMKELTALTIDVI
Sbjct: 181  VAKWDKKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNYGEGRRIFELMKELTALTIDVI 240

Query: 1077 RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLEC 898
            RSVYIPG RFLPTKRNNRMRAIDKEVRVRITEIINKK K+MK+GEAA AADDFLGILLEC
Sbjct: 241  RSVYIPGHRFLPTKRNNRMRAIDKEVRVRITEIINKKTKIMKAGEAA-AADDFLGILLEC 299

Query: 897  NLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE 718
            NLNEI+EQG+NK+AGMTI EIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE
Sbjct: 300  NLNEIREQGHNKTAGMTIEEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE 359

Query: 717  VFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLM 538
            VFQVFG KTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHE TQLGKY IPAGVQLM
Sbjct: 360  VFQVFGNKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEDTQLGKYLIPAGVQLM 419

Query: 537  MPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK 358
            MPQ+LLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK
Sbjct: 420  MPQVLLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK 479

Query: 357  MAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            MAM+LILRRFSFELS SYVHAPFTLITMQPQYGAHLILHKL
Sbjct: 480  MAMTLILRRFSFELSLSYVHAPFTLITMQPQYGAHLILHKL 520


>gb|AGX93058.1| 7-deoxyloganic acid 7-hydroxylase-like protein [Amsonia hubrichtii]
          Length = 518

 Score =  970 bits (2507), Expect = 0.0
 Identities = 469/518 (90%), Positives = 498/518 (96%)
 Frame = -2

Query: 1788 NFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSGKLI 1609
            NFKS+  L FV + LYWVYR+LDWVWF+PKKLEKCLREQGFKGNPYRL LGDQY+SGKLI
Sbjct: 3    NFKSVAVLGFVCVALYWVYRLLDWVWFRPKKLEKCLREQGFKGNPYRLLLGDQYESGKLI 62

Query: 1608 RQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTKYYK 1429
            R+A++KPIG+EEDVKKRI+PH+LKTV THGK SFMWVGRIPRV +TDPELIKEVLTKYYK
Sbjct: 63   REAMSKPIGLEEDVKKRIIPHLLKTVETHGKNSFMWVGRIPRVQVTDPELIKEVLTKYYK 122

Query: 1428 FQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDMVTK 1249
            FQKNHHDLDPITKLLLTGIGSLEG+PWAKRRKIIN+AFHFEKLKLMLPAFYLSCRD+V+K
Sbjct: 123  FQKNHHDLDPITKLLLTGIGSLEGEPWAKRRKIINSAFHFEKLKLMLPAFYLSCRDLVSK 182

Query: 1248 WDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVIRSV 1069
            WD KVPEGGSAEVDVWHDIETLTGDVISRTLFGSN+EEGRRIFELMKELTALTIDVIRSV
Sbjct: 183  WDKKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNYEEGRRIFELMKELTALTIDVIRSV 242

Query: 1068 YIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLECNLN 889
            YIPGQRFLPTKRNNRMR IDKEVRVRITEIIN KMK+MK+GEA  A DDFLGILLECN N
Sbjct: 243  YIPGQRFLPTKRNNRMRTIDKEVRVRITEIINNKMKIMKTGEA--AGDDFLGILLECNQN 300

Query: 888  EIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEVFQ 709
            EI+EQGNNK+AGMTI +IIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEV Q
Sbjct: 301  EIREQGNNKNAGMTIEQIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEVLQ 360

Query: 708  VFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLMMPQ 529
            VFG KTPDYDGISHLK++TMILYEVLRLYTPVAELTKVAHE TQLGKYFIPAGVQLMMPQ
Sbjct: 361  VFGDKTPDYDGISHLKIVTMILYEVLRLYTPVAELTKVAHEDTQLGKYFIPAGVQLMMPQ 420

Query: 528  ILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMAM 349
            +LLHHDP+IWGEDVMEFKPERF+EGVLKATKSQGS+FPFSLGPRMCIGQNFALLEAKMAM
Sbjct: 421  MLLHHDPQIWGEDVMEFKPERFSEGVLKATKSQGSYFPFSLGPRMCIGQNFALLEAKMAM 480

Query: 348  SLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            +LILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL
Sbjct: 481  ALILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 518


>gb|AGX93060.1| 7-deoxyloganic acid 7-hydroxylase-like protein [Tabernaemontana
            elegans]
          Length = 519

 Score =  967 bits (2500), Expect = 0.0
 Identities = 467/521 (89%), Positives = 499/521 (95%)
 Frame = -2

Query: 1797 MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG 1618
            ME+NFK +  L F+ L LYWVYR+LDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQY+SG
Sbjct: 1    MEMNFKLVAVLGFIGLALYWVYRVLDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYESG 60

Query: 1617 KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK 1438
            KLIR+A++KPIGVEEDVKKRI+PHILKTV THGK SFMWVGRIPRV++TDPELIKEVLTK
Sbjct: 61   KLIREAMSKPIGVEEDVKKRIIPHILKTVETHGKNSFMWVGRIPRVHVTDPELIKEVLTK 120

Query: 1437 YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 1258
            YYKFQKNHHDLDPITK LLTGIGSLEG+PWAKRRKIINAAFHFEKLKLMLPAFYLSCRD+
Sbjct: 121  YYKFQKNHHDLDPITKFLLTGIGSLEGEPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDL 180

Query: 1257 VTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVI 1078
            V+KWD KVPEGGSAEVDVWHDIETLTGDVISRTLFGSN+EEGRRIFELMKELTALTIDVI
Sbjct: 181  VSKWDKKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNYEEGRRIFELMKELTALTIDVI 240

Query: 1077 RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLEC 898
            RSVYIPGQRFLPTKRNN+MRAIDKEVRVRI EII+ KMK++K+G+  +A DDFLGILLEC
Sbjct: 241  RSVYIPGQRFLPTKRNNKMRAIDKEVRVRIKEIIDNKMKILKAGK--TAGDDFLGILLEC 298

Query: 897  NLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE 718
            NLNEI+EQGNNK+AGMTI +IIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQ RAREE
Sbjct: 299  NLNEIREQGNNKNAGMTIEQIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQNRAREE 358

Query: 717  VFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLM 538
            V QVFG KTPDYDGISHLK +TMILYEVLR+YTPVAELTKVAHE TQLGKYFIPAGVQLM
Sbjct: 359  VLQVFGNKTPDYDGISHLKTVTMILYEVLRIYTPVAELTKVAHEDTQLGKYFIPAGVQLM 418

Query: 537  MPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK 358
            MPQ+LLHHDP+IWGEDVMEFKPERF+EGVLKATKSQGS+FPFSLGPRMCIGQNFALLEAK
Sbjct: 419  MPQMLLHHDPQIWGEDVMEFKPERFSEGVLKATKSQGSYFPFSLGPRMCIGQNFALLEAK 478

Query: 357  MAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            MAM+LIL RFSFELSPSYVHAPFTLITMQPQYGAHLILHKL
Sbjct: 479  MAMALILCRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 519


>gb|AGX93061.1| 7-deoxyloganic acid 7-hydroxylase-like protein [Vinca minor]
          Length = 520

 Score =  956 bits (2472), Expect = 0.0
 Identities = 466/519 (89%), Positives = 496/519 (95%)
 Frame = -2

Query: 1791 LNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSGKL 1612
            +NF S+  L F+SL+++W+YR+LDWVWF+PKKLEKCLREQGFKGNPYRLFLGDQY+SGKL
Sbjct: 4    MNFNSVAILGFISLSIFWIYRVLDWVWFRPKKLEKCLREQGFKGNPYRLFLGDQYESGKL 63

Query: 1611 IRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTKYY 1432
            IR+A++KPIG++EDVKKRIVPHILK V THGK SFMWVGRI RV ITDPELIKEVLTKYY
Sbjct: 64   IREAMSKPIGIDEDVKKRIVPHILKAVETHGKNSFMWVGRILRVQITDPELIKEVLTKYY 123

Query: 1431 KFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDMVT 1252
            KFQKNHHDLDPITKLLL GIGSLEG+ WAKRRKIIN+AFHFEKLKLMLPAFYLSCRDMV 
Sbjct: 124  KFQKNHHDLDPITKLLLGGIGSLEGESWAKRRKIINSAFHFEKLKLMLPAFYLSCRDMVE 183

Query: 1251 KWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVIRS 1072
            KWD KVPEGGS+EV+VWHDIETLTGDVISRTLFGSN+EEGRRIFELMKELTALTIDVIRS
Sbjct: 184  KWDKKVPEGGSSEVEVWHDIETLTGDVISRTLFGSNYEEGRRIFELMKELTALTIDVIRS 243

Query: 1071 VYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLECNL 892
            VYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMK+MK+GE  +AADDFLGILLE NL
Sbjct: 244  VYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKIMKAGE--TAADDFLGILLENNL 301

Query: 891  NEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEVF 712
            NEI+EQGNN++AGMTI +IIGECKLFYFAGQDTTSTL+VWTMVLLSRFPEWQTRAREEV 
Sbjct: 302  NEIREQGNNRNAGMTIEQIIGECKLFYFAGQDTTSTLIVWTMVLLSRFPEWQTRAREEVL 361

Query: 711  QVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLMMP 532
            QVFG K PDYDGIS LKVITMILYEVLRLYTPVAELTKVAHE TQLGKYFIPAGVQLMMP
Sbjct: 362  QVFGNKPPDYDGISRLKVITMILYEVLRLYTPVAELTKVAHEDTQLGKYFIPAGVQLMMP 421

Query: 531  QILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMA 352
            Q LLHHDPEIWGEDVMEFKPERF+EGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMA
Sbjct: 422  QALLHHDPEIWGEDVMEFKPERFSEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMA 481

Query: 351  MSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            MSLILRRF+FELSPSYVHAPFTLITMQPQYGAHLILHKL
Sbjct: 482  MSLILRRFAFELSPSYVHAPFTLITMQPQYGAHLILHKL 520


>gb|AGX93057.1| 7-deoxyloganic acid 7-hydroxylase-like protein [Cinchona calisaya]
          Length = 519

 Score =  951 bits (2457), Expect = 0.0
 Identities = 459/521 (88%), Positives = 494/521 (94%)
 Frame = -2

Query: 1797 MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG 1618
            MELNF SI  L F+ L++YW YR+LDWVW +PKKLEKCLREQGF+GNPYRLFLGDQY+SG
Sbjct: 1    MELNFTSIAILGFIGLSIYWFYRVLDWVWLRPKKLEKCLREQGFRGNPYRLFLGDQYESG 60

Query: 1617 KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK 1438
            KLIR+A++KPI V+EDV+KRI PHILKTV THGK SFMWVGRIPRVN+TDPELI+EVLTK
Sbjct: 61   KLIREAMSKPIPVDEDVRKRIAPHILKTVQTHGKNSFMWVGRIPRVNVTDPELIREVLTK 120

Query: 1437 YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 1258
            YYKFQKNHHDLDPITKLLLTGIGSLEGDPW++RRKIIN+AF FEKLKLMLPAFYLSCRDM
Sbjct: 121  YYKFQKNHHDLDPITKLLLTGIGSLEGDPWSRRRKIINSAFQFEKLKLMLPAFYLSCRDM 180

Query: 1257 VTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVI 1078
            V+KWDNKVPE  SAE+DVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELT+LTIDVI
Sbjct: 181  VSKWDNKVPEDDSAELDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTSLTIDVI 240

Query: 1077 RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLEC 898
            RSVYIPGQRFLPTKRNNRMRAID+EVRVRITEIINKKM+ MK+GEA    DDFLGILLEC
Sbjct: 241  RSVYIPGQRFLPTKRNNRMRAIDREVRVRITEIINKKMRAMKAGEA--TGDDFLGILLEC 298

Query: 897  NLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE 718
            NLNEIKEQGNNKSAGM+I EIIGECKLFYFAGQDTTSTL+VWTMVLLSRFPEWQ  AREE
Sbjct: 299  NLNEIKEQGNNKSAGMSIEEIIGECKLFYFAGQDTTSTLIVWTMVLLSRFPEWQQHAREE 358

Query: 717  VFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLM 538
            V QVFG + PDYDGIS LK++TMILYEVLR+YTPV+ELTKVAHE TQLGKYFIPAGVQLM
Sbjct: 359  VLQVFGDRKPDYDGISRLKIVTMILYEVLRIYTPVSELTKVAHEDTQLGKYFIPAGVQLM 418

Query: 537  MPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK 358
            MPQILLHHDPEIWG+DVMEFKP+RF+EGVLKATKSQGS+FPFSLGPRMCIGQNFALLEAK
Sbjct: 419  MPQILLHHDPEIWGDDVMEFKPQRFSEGVLKATKSQGSYFPFSLGPRMCIGQNFALLEAK 478

Query: 357  MAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            MAM+LILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL
Sbjct: 479  MAMALILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 519


>gb|AGX93056.1| 7-deoxyloganic acid 7-hydroxylase-like protein [Lonicera japonica]
          Length = 519

 Score =  809 bits (2090), Expect = 0.0
 Identities = 391/512 (76%), Positives = 455/512 (88%), Gaps = 1/512 (0%)
 Frame = -2

Query: 1767 LVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSGKLIRQALTKP 1588
            L+F  +T YWVY  L+W+WF+PKKLEKCLREQGF GN YRLFLGDQ +S  +IR A+++P
Sbjct: 12   LIFGVIT-YWVYSFLNWIWFRPKKLEKCLREQGFGGNAYRLFLGDQQESKVMIRDAMSRP 70

Query: 1587 IGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTKYYKFQKNHHD 1408
            I + +D+K+R++PH+LKT+  HGK SFMWVGR+PR++IT+PELI++VLTKYYKFQKNHH 
Sbjct: 71   ITLSDDIKQRVIPHVLKTMNNHGKNSFMWVGRMPRLHITEPELIRDVLTKYYKFQKNHHS 130

Query: 1407 LDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDMVTKWDNKVP- 1231
            LDPITK LL+GIGSLEG+PWA+RR++IN+AFHFEKLKLMLPAFYLSC DMV KW+  V  
Sbjct: 131  LDPITKYLLSGIGSLEGEPWAQRRRVINSAFHFEKLKLMLPAFYLSCLDMVNKWEKVVSS 190

Query: 1230 EGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVIRSVYIPGQR 1051
            +GGS EV+V HD+ETLTGDVISRTLFGSNFEEG++IFELMKELT LTI VI+SVYIPG R
Sbjct: 191  KGGSVEVEVHHDLETLTGDVISRTLFGSNFEEGKKIFELMKELTVLTIQVIQSVYIPGWR 250

Query: 1050 FLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLECNLNEIKEQG 871
            F+PTKRNNR++ IDK+VRV ITEIIN KMK MK+GE++S+  DFLGILLECN+ EI EQ 
Sbjct: 251  FMPTKRNNRIKKIDKDVRVSITEIINNKMKAMKAGESSSS--DFLGILLECNMTEI-EQT 307

Query: 870  NNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEVFQVFGYKT 691
             NK+AG++I EIIGECKLFYFAGQDTTSTLL WTMV+LSRFP+WQ RAREEV QVFG   
Sbjct: 308  KNKNAGLSIEEIIGECKLFYFAGQDTTSTLLCWTMVILSRFPDWQARAREEVLQVFGDGK 367

Query: 690  PDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLMMPQILLHHD 511
            PDYDGI+ LK +TMILYEVLRLY PV ELTKVAHE T+LG   IPAGVQ+M+P ILLHH+
Sbjct: 368  PDYDGINRLKTVTMILYEVLRLYPPVVELTKVAHEDTKLGDLTIPAGVQVMLPTILLHHN 427

Query: 510  PEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMAMSLILRR 331
            P+IWGEDV EFKPERFA+GVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMA++LIL R
Sbjct: 428  PDIWGEDVDEFKPERFAQGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMALALILPR 487

Query: 330  FSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            FSFELSPSYVHAP+TLITMQPQ+GAHLILHK+
Sbjct: 488  FSFELSPSYVHAPYTLITMQPQFGAHLILHKI 519


>gb|ADU19849.1| putative secologanin synthase [Camptotheca acuminata]
          Length = 524

 Score =  639 bits (1647), Expect = e-180
 Identities = 299/522 (57%), Positives = 401/522 (76%)
 Frame = -2

Query: 1800 EMELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDS 1621
            +M++ +KSI   V V   +Y  +++L+W +  PK++EKCLR+QGFKGN YRL +GD  +S
Sbjct: 4    QMDVLYKSIAASVAVVFLVY-AWKMLNWAYLTPKRIEKCLRKQGFKGNSYRLLVGDLKES 62

Query: 1620 GKLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLT 1441
              ++++ ++KPI V ED+ +R++PH++KT+ T+GK SF W+GR+PRV+I +P+LIK++L 
Sbjct: 63   SMMLKETMSKPINVSEDIVERVMPHVIKTIDTYGKNSFTWIGRMPRVHIMEPDLIKDILA 122

Query: 1440 KYYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRD 1261
             +  F KNHH  +P+TK LLTGIGSLEGD WAK R+II+ +FH EKLK MLPAFY+S  D
Sbjct: 123  NHNDFMKNHHAYNPLTKFLLTGIGSLEGDKWAKHRRIISPSFHLEKLKTMLPAFYVSYDD 182

Query: 1260 MVTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDV 1081
            ++TKW+ +    GS E+D++   +TLT DVISR  FGS++ EG RIF L+KEL  LT+DV
Sbjct: 183  LLTKWEQQCSSKGSVEIDLFPTFDTLTSDVISRVAFGSSYGEGGRIFILLKELMDLTVDV 242

Query: 1080 IRSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLE 901
            +RSVY+PG  FLPTKRNNRMR +D E++ R++ IIN ++K MK+GE   + +D LG LLE
Sbjct: 243  MRSVYVPGSSFLPTKRNNRMREVDGEIKDRLSGIINSRVKAMKAGE--PSGEDLLGTLLE 300

Query: 900  CNLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRARE 721
             N  EI+  GN K+AGM+I ++I ECKLFYFAGQ+TT  LL WT VLLSR PEWQ RARE
Sbjct: 301  SNFKEIERLGNKKNAGMSIEDVISECKLFYFAGQETTGILLTWTCVLLSRHPEWQERARE 360

Query: 720  EVFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQL 541
            E+FQVFG    D+D + +LK++ MILYEVLRLY PV ELTKV +E  +LG   IPAGVQL
Sbjct: 361  EIFQVFGNGKVDFDRVQNLKIVPMILYEVLRLYPPVIELTKVTYEEQKLGNLTIPAGVQL 420

Query: 540  MMPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEA 361
            MMP ILLH D E+WG D  EF P RFA+G+ KA KS   + PFS GPR+C+GQNFALL+A
Sbjct: 421  MMPSILLHRDQEMWGADSKEFNPGRFADGISKAVKSPFFYIPFSWGPRICVGQNFALLQA 480

Query: 360  KMAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            KMA+++IL+RF+F+LSP+Y HAPFT++T+QPQ+GA ++  K+
Sbjct: 481  KMALTMILQRFTFDLSPTYAHAPFTVLTLQPQHGAQVVFRKI 522


>dbj|BAL45198.1| cytochrome P450 monooxygenase [Medicago truncatula]
          Length = 518

 Score =  629 bits (1622), Expect = e-177
 Identities = 297/515 (57%), Positives = 388/515 (75%)
 Frame = -2

Query: 1779 SIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSGKLIRQA 1600
            +II L  ++L+L W +RIL+W+W KPKKLEK LREQG KGN YRL +GD  D  K+ ++A
Sbjct: 6    TIILLTLMTLSLIWAWRILNWLWLKPKKLEKLLREQGLKGNSYRLLVGDIKDLLKIRKEA 65

Query: 1599 LTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTKYYKFQK 1420
             TKP+ + +D+  R+   + ++V  HGK SF+W G  PRVNITDP+ IK+VL K Y FQK
Sbjct: 66   TTKPMNLSDDIVPRVYSFVHQSVTKHGKNSFIWFGPTPRVNITDPDQIKDVLNKIYDFQK 125

Query: 1419 NHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDMVTKWDN 1240
             +   +P+ +LL  G+ SLEG+ W+K RKIIN AFH EKLK+MLP F+ SC DM++KW+ 
Sbjct: 126  PN--ANPLVRLLANGLVSLEGEQWSKHRKIINPAFHLEKLKIMLPIFHKSCDDMISKWEK 183

Query: 1239 KVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVIRSVYIP 1060
             +   GS E+DVW  ++    DVISR  FGS++EEG+RIF+L  E   LT  ++  VYIP
Sbjct: 184  MLSSDGSCEMDVWPFLQNFASDVISRAAFGSSYEEGKRIFQLQTEQAELTTKIMMKVYIP 243

Query: 1059 GQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLECNLNEIK 880
            G RFLPT    RM+ ID++++  +T++IN + + +K+GEA    DD LGILLE N  E++
Sbjct: 244  GWRFLPTATPRRMKEIDRDIKASLTDMINNRERALKAGEATK--DDLLGILLESNHKEME 301

Query: 879  EQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEVFQVFG 700
            E GNNK  GM++ ++I ECKLFYFAGQ+TTS LLVWTMVLLSR+P+WQ RAREEV QVFG
Sbjct: 302  EHGNNKDVGMSLDDVIEECKLFYFAGQETTSVLLVWTMVLLSRYPDWQARAREEVLQVFG 361

Query: 699  YKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLMMPQILL 520
               PD+DG+SHLK++TMILYEVLRLY PV  L +  H+  +LG   +PAGVQ+ +  I++
Sbjct: 362  NNKPDFDGLSHLKIVTMILYEVLRLYPPVIALARRVHKDVKLGNLALPAGVQVFLSIIMV 421

Query: 519  HHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMAMSLI 340
            HHD E+WGED   F PERF+EGVLKAT  + SFFPF+ GPR+CIGQNF++LEAKMA+++I
Sbjct: 422  HHDIELWGEDAKVFNPERFSEGVLKATNGRNSFFPFAGGPRICIGQNFSMLEAKMAIAMI 481

Query: 339  LRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            L+RFSFELSPSY HAP T+IT+QPQYGAH+ILHKL
Sbjct: 482  LQRFSFELSPSYAHAPATVITLQPQYGAHIILHKL 516


>gb|ABC59078.1| cytochrome P450 monooxygenase CYP72A59 [Medicago truncatula]
          Length = 518

 Score =  626 bits (1614), Expect = e-176
 Identities = 294/515 (57%), Positives = 387/515 (75%)
 Frame = -2

Query: 1779 SIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSGKLIRQA 1600
            +II    ++L+L W +RIL+W+W KPKKLEK LREQG KGN YRL +GD  D  K+ ++A
Sbjct: 6    TIILFTLMTLSLIWAWRILNWLWLKPKKLEKLLREQGLKGNSYRLLVGDMNDLLKMRKEA 65

Query: 1599 LTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTKYYKFQK 1420
             +KP+ + +D+  R+   + ++V  HGK SF+W G  PRVNITDP+ IK+VL K Y FQK
Sbjct: 66   TSKPMNLSDDIVPRVYSFVHQSVTKHGKNSFIWFGPTPRVNITDPDQIKDVLNKIYDFQK 125

Query: 1419 NHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDMVTKWDN 1240
             +   +P+ +LL  G+ SLEG+ W+K RKIIN AFH EKLK+MLP F+ SC D+++KW+ 
Sbjct: 126  PN--ANPLVRLLANGLVSLEGEQWSKHRKIINPAFHLEKLKIMLPIFHKSCDDLISKWEK 183

Query: 1239 KVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVIRSVYIP 1060
             +   GS E+DVW  ++    DVISR  FGS++EEG+RIF+L  E   LT  ++  VYIP
Sbjct: 184  MLSSDGSCEMDVWPFLQNFASDVISRAAFGSSYEEGKRIFQLQTEQAELTTKIMMKVYIP 243

Query: 1059 GQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLECNLNEIK 880
            G RFLPT    RM+ ID++++  +T++IN + + +K+GEA    DD LGILLE N  E++
Sbjct: 244  GWRFLPTATPRRMKEIDRDIKASLTDMINNRERALKAGEATK--DDLLGILLESNHKEME 301

Query: 879  EQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEVFQVFG 700
            E GNNK  GM++ ++I ECKLFYFAGQ+TTS LLVWTMVLLSR+P+WQ RAREEV QVFG
Sbjct: 302  EHGNNKDVGMSLDDVIEECKLFYFAGQETTSVLLVWTMVLLSRYPDWQARAREEVLQVFG 361

Query: 699  YKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLMMPQILL 520
               PD+DG+SHLK++TMILYEVLRLY PV  L +  H+  +LG   +PAGVQ+ +  I++
Sbjct: 362  NNKPDFDGLSHLKIVTMILYEVLRLYPPVIALARRVHKDVKLGNLALPAGVQVFLSIIMV 421

Query: 519  HHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMAMSLI 340
            HHD E+WGED   F PERF+EGVLKAT  + SFFPF+ GPR+CIGQNF++LEAKMA+++I
Sbjct: 422  HHDIELWGEDAKVFNPERFSEGVLKATNGRNSFFPFAGGPRICIGQNFSMLEAKMAIAMI 481

Query: 339  LRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            L+RFSFELSPSY HAP T+IT+QPQYGAH+ILHKL
Sbjct: 482  LQRFSFELSPSYAHAPATVITLQPQYGAHIILHKL 516


>gb|EXB52089.1| Secologanin synthase [Morus notabilis]
          Length = 558

 Score =  624 bits (1609), Expect = e-176
 Identities = 305/558 (54%), Positives = 395/558 (70%), Gaps = 40/558 (7%)
 Frame = -2

Query: 1791 LNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSGKL 1612
            L F S++F + +  T  WV+R+++WVW +PK+LEKCLR+QG KGN YR   GD  +S  +
Sbjct: 6    LRFSSVLFAIILITT--WVWRVVNWVWLRPKRLEKCLRKQGLKGNSYRFLFGDLKESISM 63

Query: 1611 IRQALTKPIGVEEDVKKRIVPHILKTV-------------------GTHG---------- 1519
             ++A +KPI + +D+  R+ P +L+TV                   GT G          
Sbjct: 64   YKEARSKPINLSDDITTRVFPFVLQTVQKYGMYLYSTQSGGQTVIFGTQGSQIDHKTLFN 123

Query: 1518 -----------KKSFMWVGRIPRVNITDPELIKEVLTKYYKFQKNHHDLDPITKLLLTGI 1372
                       K SFMW+G  PRVNIT+PE +K++  K   F K H++  P+ +LL TG+
Sbjct: 124  KRKAFSFPVSGKDSFMWIGPNPRVNITNPEHLKDIFNKIGDFPKPHNN--PLVELLATGL 181

Query: 1371 GSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDMVTKWDNKVPEGGSAEVDVWHDI 1192
             S EG+ WAK RKIIN AFH EKLK MLPAFYLSC +M+ KW++ +   GS E+DVW  +
Sbjct: 182  ASYEGEKWAKHRKIINPAFHVEKLKHMLPAFYLSCNEMLKKWESFLNNEGSCEIDVWPYL 241

Query: 1191 ETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVIRSVYIPGQRFLPTKRNNRMRAI 1012
            + +TGDVISRT FGS++EEGRRIF+L +E   L I  I++VY+PG RF PT  N RM+ +
Sbjct: 242  QNMTGDVISRTAFGSSYEEGRRIFQLQREQAELAIKAIQTVYVPGWRFAPTTLNKRMKEV 301

Query: 1011 DKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLECNLNEIKEQGNNKSAGMTIGEII 832
            D EV+  + +II+K+ K M++GEA +  DD LGIL+E N  EI+E GNNK+ G++I ++I
Sbjct: 302  DHEVQGLLKDIIHKREKAMRAGEAPN--DDLLGILMESNFKEIQEHGNNKNMGISIRDVI 359

Query: 831  GECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEVFQVFGYKTPDYDGISHLKVIT 652
             ECKLFYFAGQ+TTS LLVWTMVLLSR+P+WQ RAREEV QVFGY  PD+DG+ HLK++T
Sbjct: 360  EECKLFYFAGQETTSVLLVWTMVLLSRYPDWQARAREEVLQVFGYNNPDFDGLGHLKIVT 419

Query: 651  MILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLMMPQILLHHDPEIWGEDVMEFKP 472
            MILYEVLR Y PV  LT+   + TQLG   +P GVQ+ +P IL+H D  +WGED  EFKP
Sbjct: 420  MILYEVLRFYPPVILLTRTVQKQTQLGNLSLPPGVQISLPVILVHRDTNLWGEDAKEFKP 479

Query: 471  ERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMAMSLILRRFSFELSPSYVHAP 292
            ERFAEGV KATK Q SFFPF  GPR+CIGQNFA++EAKMA++LIL+RF+FELSPSY HAP
Sbjct: 480  ERFAEGVSKATKGQVSFFPFGWGPRICIGQNFAMIEAKMALALILQRFTFELSPSYAHAP 539

Query: 291  FTLITMQPQYGAHLILHK 238
             T+IT+QPQYGAH+ LHK
Sbjct: 540  CTVITLQPQYGAHITLHK 557


>ref|XP_004488668.1| PREDICTED: secologanin synthase-like [Cicer arietinum]
          Length = 519

 Score =  623 bits (1607), Expect = e-176
 Identities = 297/515 (57%), Positives = 387/515 (75%)
 Frame = -2

Query: 1779 SIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSGKLIRQA 1600
            +II      L+L W +R+L+W+W KPKKLEK LREQGFKGN YRL +GD  D  K  ++A
Sbjct: 7    AIILFTLTILSLTWAWRMLNWLWLKPKKLEKLLREQGFKGNSYRLLVGDVRDLLKTRKEA 66

Query: 1599 LTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTKYYKFQK 1420
             +KP+ + +D+  R+  ++  +V  +GK SFMW G IPRVNITDPE IK+VL K Y F+K
Sbjct: 67   TSKPMNLSDDIGPRVFSYVHHSVTKYGKNSFMWFGPIPRVNITDPEQIKDVLNKIYDFRK 126

Query: 1419 NHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDMVTKWDN 1240
             + +  P+ +LL  G+ S EG+ W K RKIIN AFH EKLK+MLP F+ SC D+++KW+ 
Sbjct: 127  PNSN--PLVRLLANGLVSYEGEKWNKHRKIINPAFHLEKLKIMLPIFFKSCDDLISKWEK 184

Query: 1239 KVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVIRSVYIP 1060
             +   GS E+DVW  ++ L  DVISRT FGS+FEEG+RIF+L  E   LT  ++  VYIP
Sbjct: 185  MLSLEGSCEMDVWPFLQNLASDVISRTAFGSSFEEGKRIFQLQIEQAELTKQIMMKVYIP 244

Query: 1059 GQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLECNLNEIK 880
            G RFLPT  + RM+ ID++++  +T++INK+ K +K+GEA    DD LGILLE N  E++
Sbjct: 245  GWRFLPTTTHKRMKEIDRDIKASLTDMINKREKALKAGEATK--DDLLGILLESNHREME 302

Query: 879  EQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREEVFQVFG 700
            E GNNK+ GM++ ++I ECKLFYFAGQ+TTS LLVWTMV LSR+P+WQ RAREEVFQVFG
Sbjct: 303  EHGNNKNVGMSLEDVIEECKLFYFAGQETTSVLLVWTMVCLSRYPDWQARAREEVFQVFG 362

Query: 699  YKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLMMPQILL 520
             K PD+DG+SHLK++TMIL EVLRLY PV  L +  H+  +LG   +PAGVQ+ +P +L+
Sbjct: 363  NKKPDFDGLSHLKIVTMILNEVLRLYPPVIALARSVHKDVKLGNITLPAGVQVSLPVVLV 422

Query: 519  HHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAKMAMSLI 340
            HHD E+WG+D   F PERF+EGVLKAT  + SFFPF  GPR+CIGQNF++LEAKMAM++I
Sbjct: 423  HHDCELWGDDAKVFNPERFSEGVLKATNGKVSFFPFGGGPRICIGQNFSMLEAKMAMAMI 482

Query: 339  LRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            L+ FSFELSPSY HAP T+IT+QPQYGAH+IL K+
Sbjct: 483  LQHFSFELSPSYAHAPATVITLQPQYGAHIILRKV 517


>gb|EXB52087.1| Secologanin synthase [Morus notabilis]
          Length = 518

 Score =  619 bits (1597), Expect = e-174
 Identities = 296/521 (56%), Positives = 387/521 (74%), Gaps = 1/521 (0%)
 Frame = -2

Query: 1797 MELNFKSIIFLVFVSLTLY-WVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDS 1621
            ME++F  +  +VF  L +  W +R+L+WVW +PK+LE CLR+QG KGN YRL+ GD  +S
Sbjct: 1    MEVSFLKLSSVVFAILLITTWAWRVLNWVWLRPKRLENCLRKQGLKGNSYRLWSGDLKES 60

Query: 1620 GKLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLT 1441
              +I++A +KPI + ED+  RI P  L TV  +GK SFMW+G  PRV+IT+PE IK++  
Sbjct: 61   SLMIKEASSKPINLSEDITARIFPFGLHTVNNYGKDSFMWIGPTPRVSITNPEYIKDIFN 120

Query: 1440 KYYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRD 1261
            K   F K      P+ KLL TG+ + EG+ W + RKIIN AFH EKLK ++PAFYLSC +
Sbjct: 121  KLGDFPKPQSI--PLVKLLATGVATYEGEKWTRHRKIINPAFHMEKLKRLVPAFYLSCSE 178

Query: 1260 MVTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDV 1081
            M+ KW+  +   GS E+DVW  ++ +TGDVISRT FGS++EEGRRIF+L KE   L I  
Sbjct: 179  MLNKWERLLNSEGSCELDVWSYLQNMTGDVISRTAFGSSYEEGRRIFQLQKEQGELAIKS 238

Query: 1080 IRSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLE 901
            +++VYIPG RF+PTK N RM+ I  E+   +  II+K+   M++GEA +  DD LGIL+E
Sbjct: 239  LQTVYIPGWRFVPTKLNRRMKKIYNEIEALVKNIIHKREGAMRAGEAPN--DDLLGILME 296

Query: 900  CNLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRARE 721
             NL EI+E GNNK+ G++I ++I ECKLFY AGQ+TTSTLLVWTMVLLSRFP WQ RARE
Sbjct: 297  SNLKEIQEHGNNKNMGISIRDVIEECKLFYIAGQETTSTLLVWTMVLLSRFPSWQDRARE 356

Query: 720  EVFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQL 541
            EV Q+FG   P +DG++ LKV+TMI YEVLRLY P+   T+   + TQLG   +PAGV++
Sbjct: 357  EVLQIFGNNKPGFDGLTQLKVVTMIFYEVLRLYPPLILFTRKVEKKTQLGNLSLPAGVEV 416

Query: 540  MMPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEA 361
             +P IL+H D E+WGED  +FKPERFAEG+ K TK Q SFFPF  GPR+C+GQNFA++EA
Sbjct: 417  SIPTILVHRDTELWGEDAKDFKPERFAEGMSKVTKGQVSFFPFGWGPRICVGQNFAMVEA 476

Query: 360  KMAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHK 238
            KMA++LIL+RF+FELSPSY HAP T++T+QPQYGAH+ILHK
Sbjct: 477  KMALALILQRFTFELSPSYAHAPLTILTLQPQYGAHIILHK 517


>ref|XP_002333744.1| cytochrome P450 [Populus trichocarpa]
          Length = 518

 Score =  619 bits (1595), Expect = e-174
 Identities = 298/523 (56%), Positives = 390/523 (74%), Gaps = 2/523 (0%)
 Frame = -2

Query: 1797 MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG 1618
            M +   SI+  +     L W +R+L+WVWF+PKK+E+CLR+QGF G PYRL  GD  ++ 
Sbjct: 1    MTVTVTSILVSIVYVAVLRWAWRVLNWVWFRPKKVERCLRQQGFAGKPYRLLFGDWKENS 60

Query: 1617 KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK 1438
             ++++A TKPIG+ + +  R++P + + V  +GK SFMW+G  PRVNI +P+ I++V  K
Sbjct: 61   DMLKEARTKPIGLSDALLPRVMPFLHQLVKDYGKNSFMWIGPKPRVNIMNPDQIRDVFMK 120

Query: 1437 YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 1258
              ++QK  H   P+ K L  G+ S EG+ WAK RKIIN AFH EKLKLM+PAFY SC  M
Sbjct: 121  INEYQKPSH---PLLKPLACGLASHEGEKWAKHRKIINPAFHQEKLKLMIPAFYESCSGM 177

Query: 1257 VTKWDNKVP-EGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDV 1081
            + KW+  V  + GS E+DVW D++ LT D ISRT FGSN+EEG+RIF+L+KELT LT+ V
Sbjct: 178  INKWEKLVSVDEGSCELDVWPDLQGLTCDAISRTSFGSNYEEGKRIFDLLKELTDLTVHV 237

Query: 1080 I-RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILL 904
            I ++  IPG RFLP   N R++AIDKE++  +  +INK+ K M +GE   A +D LG+LL
Sbjct: 238  IIKAFVIPGYRFLPIPTNRRLKAIDKEIKASLNALINKREKAMSAGE--DAKNDLLGLLL 295

Query: 903  ECNLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAR 724
            E N  EI+E GN KS  M+I ++I ECK+FYFAGQ+TTS LL WTMVLL+++P WQ RAR
Sbjct: 296  ESNFREIQEHGNTKSVRMSIEDVIDECKIFYFAGQETTSVLLTWTMVLLAQYPNWQARAR 355

Query: 723  EEVFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQ 544
            EEV QVFG K PD+DG++HLKV+TMILYEVLRLY PV  L +  HE  +LG   +PAGVQ
Sbjct: 356  EEVVQVFGNKKPDFDGLNHLKVVTMILYEVLRLYPPVIMLNRDVHEEIKLGNLLLPAGVQ 415

Query: 543  LMMPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLE 364
            + +P ILLH D E+WG+D  EFKPERFAEGV KATKSQ SF PF  GPR+C+GQNFAL+E
Sbjct: 416  ISLPTILLHQDHELWGDDASEFKPERFAEGVSKATKSQVSFLPFGWGPRICVGQNFALIE 475

Query: 363  AKMAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            AKMA++++L+R+SFELSPSY+HAP T+IT+QPQ+GA +IL KL
Sbjct: 476  AKMALAMVLQRYSFELSPSYIHAPRTVITLQPQHGAPMILRKL 518


>gb|AGX93064.1| secologanin synthase [Catharanthus roseus]
          Length = 527

 Score =  618 bits (1594), Expect = e-174
 Identities = 287/522 (54%), Positives = 392/522 (75%)
 Frame = -2

Query: 1800 EMELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDS 1621
            +M++  K+I   +F +L + W +R+LDW WF PK++EK LR+QGF+GNPYR  +GD  +S
Sbjct: 4    DMDIIRKAIAATIF-ALVMAWAWRVLDWAWFTPKRIEKRLRQQGFRGNPYRFLVGDVKES 62

Query: 1620 GKLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLT 1441
            GK+ ++AL+ P+  + D+  R++PHI  T+ T+G+ SF W+GRIPR+++ +PELIKEVLT
Sbjct: 63   GKMHQEALSNPMEFDNDIVPRLMPHINHTIKTYGRNSFTWMGRIPRIHVMEPELIKEVLT 122

Query: 1440 KYYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRD 1261
               K+QKN    +P+ K LLTG+GS EG  W+K R+II+ AF  EKLK MLPAF +   D
Sbjct: 123  HSSKYQKNFDVHNPLVKFLLTGVGSFEGAKWSKHRRIISPAFTLEKLKSMLPAFAICYHD 182

Query: 1260 MVTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDV 1081
            M+TKW+    + GS EVD++   + LT DVIS+  FGS ++EG +IF L+KEL  LTID 
Sbjct: 183  MLTKWEKLAEKEGSHEVDIFPTFDVLTSDVISKVAFGSTYDEGGKIFRLLKELMDLTIDC 242

Query: 1080 IRSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLE 901
            +R VYIPG  +LPTKRN RM+ I+KE+   +  IINK+MK +K+GE     DD LG+LLE
Sbjct: 243  MRDVYIPGWSYLPTKRNKRMKEINKEITDMLRFIINKRMKALKAGEPGE--DDLLGVLLE 300

Query: 900  CNLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRARE 721
             N+ EI++QGN K  GMTI ++I ECKLFYFAGQ+TT  LL WT +LLS+ PEWQ RARE
Sbjct: 301  SNIQEIQKQGNRKDGGMTINDVIEECKLFYFAGQETTGVLLTWTTILLSKHPEWQERARE 360

Query: 720  EVFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQL 541
            EV Q FG   P+++ ++HLK ++MILYEVLRLY PV +LTK+ HE T+LG Y IPAG Q+
Sbjct: 361  EVLQAFGKNKPEFERLNHLKYVSMILYEVLRLYPPVIDLTKIIHEDTKLGPYTIPAGTQV 420

Query: 540  MMPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEA 361
            M+P ++LH +  IWGED MEF P RFA+GV  ATK+  ++ PFS GPR+C+GQNFALL+A
Sbjct: 421  MLPTVMLHREKSIWGEDAMEFNPMRFADGVANATKNNVTYLPFSWGPRVCLGQNFALLQA 480

Query: 360  KMAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            K+ +++IL+RF F+++PSYVHAPFT++T+QPQ+G+H+I  KL
Sbjct: 481  KLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFGSHVIYKKL 522


>ref|XP_002331333.1| cytochrome P450 [Populus trichocarpa]
          Length = 518

 Score =  618 bits (1593), Expect = e-174
 Identities = 298/523 (56%), Positives = 390/523 (74%), Gaps = 2/523 (0%)
 Frame = -2

Query: 1797 MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG 1618
            M +   SI+  +     L W +R+L+WVWF+PKK+E+CLR+QGF G PYRL  GD  +S 
Sbjct: 1    MTVTVTSILVSIVYVAVLRWAWRVLNWVWFRPKKVERCLRQQGFAGKPYRLLFGDWKESS 60

Query: 1617 KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK 1438
             ++++A TKPIG+ + +  R++P + + V  +GK SFMWVG  PRVNI +P+ I++V  K
Sbjct: 61   DMLKEARTKPIGLSDALLPRVMPFLHQLVKDYGKNSFMWVGPKPRVNIMNPDQIRDVFMK 120

Query: 1437 YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 1258
              ++QK  H   P+ KL++ G+ S EG+ WAK RKIIN AFH EKLKLM+PAF  SC  M
Sbjct: 121  INEYQKASH---PLLKLIVCGLASHEGEKWAKHRKIINPAFHQEKLKLMIPAFSESCSGM 177

Query: 1257 VTKWDNKVP-EGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDV 1081
            + KW+  V  + GS E+DVW D++ LT D ISRT FGSN+EEG+RIF+L+KELT LT  V
Sbjct: 178  INKWEKLVSVDEGSCELDVWPDLQGLTCDAISRTSFGSNYEEGKRIFDLLKELTDLTAHV 237

Query: 1080 I-RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILL 904
            I +++ IPG RFLP   N R++AIDKE++  +  +INK+ K M +GE   A  D LG+LL
Sbjct: 238  IIKAIVIPGYRFLPIPSNRRLKAIDKEIKASLNALINKREKAMSAGE--DAKKDLLGLLL 295

Query: 903  ECNLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAR 724
            E N  EI+E GN KS GM+I ++I ECK+FYFAGQ+TT  LL WTMVLL+++P WQ RAR
Sbjct: 296  ESNFREIQEHGNTKSVGMSIEDVIDECKIFYFAGQETTLVLLTWTMVLLAQYPNWQARAR 355

Query: 723  EEVFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQ 544
            EEV QVFG K PD+DG++HLKV+TMILYEVLRLY PV  L +  HE  +LG   +PAGVQ
Sbjct: 356  EEVVQVFGNKKPDFDGLNHLKVVTMILYEVLRLYPPVIMLNRDVHEEIKLGNLLLPAGVQ 415

Query: 543  LMMPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLE 364
            + +P ILLH D E+WG+D  EFKPERFAEG+ KATKSQ SF PF  GPR+C+GQNFAL+E
Sbjct: 416  VSLPIILLHQDHELWGDDASEFKPERFAEGISKATKSQVSFLPFGWGPRICVGQNFALIE 475

Query: 363  AKMAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            AKMA++++L+R+SFELSPSY+HAP T+IT+QPQ+GA +IL KL
Sbjct: 476  AKMALAMVLQRYSFELSPSYIHAPRTVITLQPQHGAPMILRKL 518


>ref|XP_006477948.1| PREDICTED: secologanin synthase-like [Citrus sinensis]
          Length = 522

 Score =  617 bits (1591), Expect = e-174
 Identities = 294/521 (56%), Positives = 389/521 (74%)
 Frame = -2

Query: 1797 MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG 1618
            MEL  KSI   + +   L W +R+L+WVW +P+KLEK LR+QG KGN YRL  GD  ++ 
Sbjct: 1    MELPLKSIALTIVIVTVLTWAWRVLNWVWLRPEKLEKFLRQQGLKGNSYRLLFGDLKENS 60

Query: 1617 KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK 1438
              +++A  +P+ +++D+  R+ P + K V  +GK SFMW G  PRVNI +P+ IK + TK
Sbjct: 61   IELKEAKARPLSLDDDIAIRVNPFLHKLVNDYGKNSFMWFGPTPRVNIMNPDQIKAIFTK 120

Query: 1437 YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 1258
               FQK +    P+ +LL+ G+ +LEG+ WAK RK+IN AFH EKLKLMLPAFYLSC ++
Sbjct: 121  INDFQKVNSI--PLARLLIVGLATLEGEKWAKHRKLINPAFHQEKLKLMLPAFYLSCIEI 178

Query: 1257 VTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVI 1078
            +TKW+ ++   GS+E+DVW  +  LT DVISRT FGS++EEGRRIF+L  EL  LT+ V 
Sbjct: 179  ITKWEKQMSVEGSSELDVWPYLANLTSDVISRTAFGSSYEEGRRIFQLQAELAELTMQVF 238

Query: 1077 RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLEC 898
            RSV+IPG RFLPTKRN RM+ IDKE+R  +  II  + K M++GEAA+  DD LGIL+E 
Sbjct: 239  RSVHIPGWRFLPTKRNRRMKEIDKEIRASLMGIIKNREKAMRAGEAAN--DDLLGILMET 296

Query: 897  NLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE 718
            +  EI+E GNNK+ G ++ ++I ECKLFYFAGQ+TTS LL WTMVLLS+  +WQ RAR+E
Sbjct: 297  SFREIEEHGNNKNVGFSMNDVIEECKLFYFAGQETTSVLLNWTMVLLSKHQDWQERARQE 356

Query: 717  VFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLM 538
            V QVFG   PDYDG++HLK++ MILYEVLRLY PV  L++   + T+LG   +PAGVQ+ 
Sbjct: 357  VLQVFGNNKPDYDGLNHLKIVQMILYEVLRLYPPVTVLSRAVFKETKLGNLTLPAGVQIG 416

Query: 537  MPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK 358
            +P IL+H DPE+WG+D +EFKPERFAEG+ KA K+Q S+FPF+LGPR+C+GQNFAL+EAK
Sbjct: 417  LPMILVHQDPELWGDDAVEFKPERFAEGISKAAKNQVSYFPFALGPRICVGQNFALVEAK 476

Query: 357  MAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            MA ++IL+ +SFELSPSYVHAP  + T+ P+ G  LIL KL
Sbjct: 477  MATAMILQNYSFELSPSYVHAPTAVPTLHPELGTQLILRKL 517


>ref|XP_006477946.1| PREDICTED: secologanin synthase-like [Citrus sinensis]
          Length = 522

 Score =  617 bits (1590), Expect = e-174
 Identities = 294/521 (56%), Positives = 389/521 (74%)
 Frame = -2

Query: 1797 MELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDSG 1618
            MEL  KSI   + +   L W +R+L+WVW +PKKLEK LR+QG KGN YRL  GD  ++ 
Sbjct: 1    MELPLKSIALTIVIVTVLTWAWRVLNWVWLRPKKLEKFLRQQGLKGNSYRLLFGDLKENS 60

Query: 1617 KLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLTK 1438
              +++A  +P+ +++D+  R+ P + K V  +GK SFMW G  PRVNI +P+ IK + TK
Sbjct: 61   IELKEAKARPLSLDDDIAIRVNPFLHKLVNDYGKNSFMWFGPTPRVNIMNPDQIKAIFTK 120

Query: 1437 YYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRDM 1258
               FQK +    P+ +LL+ G+ +LEG+ WAK RK+IN AFH EKLKLMLPAFYLSC ++
Sbjct: 121  INDFQKVNSI--PLARLLIVGLATLEGEKWAKHRKLINPAFHQEKLKLMLPAFYLSCIEI 178

Query: 1257 VTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDVI 1078
            +TKW+ ++   GS+E+DVW  +  LT DVISRT FGS++EEGRRIF+L  EL  LT+ V 
Sbjct: 179  ITKWEKQMSVEGSSELDVWPYLANLTSDVISRTAFGSSYEEGRRIFQLQAELAELTMQVF 238

Query: 1077 RSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLEC 898
            RSV+IPG RFLPTKRN RM+ IDKE+R  +  II  + K M++GEAA+  +D LGIL+E 
Sbjct: 239  RSVHIPGWRFLPTKRNRRMKEIDKEIRASLMGIIKNREKAMRAGEAAN--NDLLGILMET 296

Query: 897  NLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRAREE 718
            +  EI+E GNNK+ G ++ ++I ECKLFYFAGQ+TTS LL WTMVLLS+  +WQ RAR+E
Sbjct: 297  SFREIEEHGNNKNVGFSMNDVIEECKLFYFAGQETTSVLLNWTMVLLSKHQDWQERARQE 356

Query: 717  VFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQLM 538
            V QVFG   PDYDG++HLK++ MILYEVLRLY PV  L++   + T+LG   +PAGVQ+ 
Sbjct: 357  VLQVFGNNKPDYDGLNHLKIVQMILYEVLRLYPPVTVLSRAVFKETKLGNLTLPAGVQIG 416

Query: 537  MPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEAK 358
            +P IL+H DPE+WG+D +EFKPERFAEG+ KA K+Q S+FPF+LGPR+C+GQNFAL+EAK
Sbjct: 417  LPMILVHQDPELWGDDAVEFKPERFAEGISKAAKNQVSYFPFALGPRICVGQNFALVEAK 476

Query: 357  MAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            MA ++IL+ +SFELSPSYVHAP  + T+ P+ G  LIL KL
Sbjct: 477  MATAMILQNYSFELSPSYVHAPTAVPTLHPELGTQLILRKL 517


>gb|AGX93046.1| secologanin synthase-like protein [Amsonia hubrichtii]
          Length = 524

 Score =  616 bits (1589), Expect = e-173
 Identities = 289/522 (55%), Positives = 390/522 (74%)
 Frame = -2

Query: 1800 EMELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDS 1621
            +M++  K+I   VF +L L W +R+LDW WF PK+LEK LR+QG+KGN YR  +GD  ++
Sbjct: 4    DMDIIRKAIAASVF-ALVLAWAWRVLDWAWFTPKRLEKRLRQQGYKGNAYRFLVGDVKEN 62

Query: 1620 GKLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLT 1441
            GK++++A++KP+    D+  RI+PHI  T+ T+G+ SF W+GRIPR+++ +PELIKEVLT
Sbjct: 63   GKMLQEAMSKPMAFNNDIVPRIMPHIHHTIQTYGRNSFTWMGRIPRIHVMEPELIKEVLT 122

Query: 1440 KYYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRD 1261
               K+QKN    +P+ K LLTG+GS EG  W+K R+II+ AF  EKLK MLPAF +S  D
Sbjct: 123  HSSKYQKNFDVHNPLVKFLLTGVGSFEGAKWSKHRRIISPAFTLEKLKTMLPAFAISYDD 182

Query: 1260 MVTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDV 1081
            M+ KW+    + GS EVD++   + LT DVIS+  FGS +EEG +IF+L+KEL  LTI+ 
Sbjct: 183  MLRKWEKIAEKQGSHEVDIFPTFDVLTSDVISKVAFGSTYEEGGKIFQLLKELMDLTIEC 242

Query: 1080 IRSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLE 901
            +R VYIPG  +LPTKRN RMR I+KE+   +  IINK+ K +K+GE     DD LG+LLE
Sbjct: 243  MRDVYIPGWSYLPTKRNKRMREINKELTDMLRNIINKRTKALKAGEPGE--DDLLGVLLE 300

Query: 900  CNLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRARE 721
             N  EI++QGN K+ GMTI ++I ECKLFYFAGQ+TT  LL W  +LLS+ PEWQ RARE
Sbjct: 301  SNFQEIQKQGNKKNVGMTINDVIEECKLFYFAGQETTGVLLTWATILLSKHPEWQERARE 360

Query: 720  EVFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQL 541
            EV Q FG   PD++ ++HLK ++MILYEVLRLY PV +LTK+ HE T+LG Y IPAG Q+
Sbjct: 361  EVLQAFGKNKPDFERLNHLKYVSMILYEVLRLYPPVIDLTKIVHEDTKLGPYTIPAGTQV 420

Query: 540  MMPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEA 361
            M+P ++LH +  IWGED MEF P RFA+GV  ATK+  ++ PFS GPR+C+GQNFALL+A
Sbjct: 421  MLPTVILHREKSIWGEDAMEFNPMRFADGVANATKNNVTYLPFSWGPRVCLGQNFALLQA 480

Query: 360  KMAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            K+ +++IL+RF+F++SPSY HAPFT++T+QPQ G+H+I  KL
Sbjct: 481  KLGLAMILQRFTFDVSPSYAHAPFTILTLQPQLGSHVIYKKL 522


>sp|Q05047.1|C72A1_CATRO RecName: Full=Secologanin synthase; Short=SLS; AltName:
            Full=CYPLXXII; AltName: Full=Cytochrome P450 72A1
            gi|167484|gb|AAA33106.1| cytochrome P-450 protein
            [Catharanthus roseus] gi|445604|prf||1909351A cytochrome
            P450
          Length = 524

 Score =  616 bits (1588), Expect = e-173
 Identities = 286/522 (54%), Positives = 390/522 (74%)
 Frame = -2

Query: 1800 EMELNFKSIIFLVFVSLTLYWVYRILDWVWFKPKKLEKCLREQGFKGNPYRLFLGDQYDS 1621
            +M+   K+I   +F +L + W +R+LDW WF PK++EK LR+QGF+GNPYR  +GD  +S
Sbjct: 4    DMDTIRKAIAATIF-ALVMAWAWRVLDWAWFTPKRIEKRLRQQGFRGNPYRFLVGDVKES 62

Query: 1620 GKLIRQALTKPIGVEEDVKKRIVPHILKTVGTHGKKSFMWVGRIPRVNITDPELIKEVLT 1441
            GK+ ++AL+KP+    D+  R++PHI  T+ T+G+ SF W+GRIPR+++ +PELIKEVLT
Sbjct: 63   GKMHQEALSKPMEFNNDIVPRLMPHINHTINTYGRNSFTWMGRIPRIHVMEPELIKEVLT 122

Query: 1440 KYYKFQKNHHDLDPITKLLLTGIGSLEGDPWAKRRKIINAAFHFEKLKLMLPAFYLSCRD 1261
               K+QKN    +P+ K LLTG+GS EG  W+K R+II+ AF  EKLK MLPAF +   D
Sbjct: 123  HSSKYQKNFDVHNPLVKFLLTGVGSFEGAKWSKHRRIISPAFTLEKLKSMLPAFAICYHD 182

Query: 1260 MVTKWDNKVPEGGSAEVDVWHDIETLTGDVISRTLFGSNFEEGRRIFELMKELTALTIDV 1081
            M+TKW+    + GS EVD++   + LT DVIS+  FGS +EEG +IF L+KEL  LTID 
Sbjct: 183  MLTKWEKIAEKQGSHEVDIFPTFDVLTSDVISKVAFGSTYEEGGKIFRLLKELMDLTIDC 242

Query: 1080 IRSVYIPGQRFLPTKRNNRMRAIDKEVRVRITEIINKKMKVMKSGEAASAADDFLGILLE 901
            +R VYIPG  +LPTKRN RM+ I+KE+   +  IINK+MK +K+GE     DD LG+LLE
Sbjct: 243  MRDVYIPGWSYLPTKRNKRMKEINKEITDMLRFIINKRMKALKAGEPGE--DDLLGVLLE 300

Query: 900  CNLNEIKEQGNNKSAGMTIGEIIGECKLFYFAGQDTTSTLLVWTMVLLSRFPEWQTRARE 721
             N+ EI++QGN K  GM+I ++I ECKLFYFAGQ+TT  LL WT +LLS+ PEWQ RARE
Sbjct: 301  SNIQEIQKQGNKKDGGMSINDVIEECKLFYFAGQETTGVLLTWTTILLSKHPEWQERARE 360

Query: 720  EVFQVFGYKTPDYDGISHLKVITMILYEVLRLYTPVAELTKVAHEATQLGKYFIPAGVQL 541
            EV Q FG   P+++ ++HLK ++MILYEVLRLY PV +LTK+ H+ T+LG Y IPAG Q+
Sbjct: 361  EVLQAFGKNKPEFERLNHLKYVSMILYEVLRLYPPVIDLTKIVHKDTKLGSYTIPAGTQV 420

Query: 540  MMPQILLHHDPEIWGEDVMEFKPERFAEGVLKATKSQGSFFPFSLGPRMCIGQNFALLEA 361
            M+P ++LH +  IWGED MEF P RF +GV  ATK+  ++ PFS GPR+C+GQNFALL+A
Sbjct: 421  MLPTVMLHREKSIWGEDAMEFNPMRFVDGVANATKNNVTYLPFSWGPRVCLGQNFALLQA 480

Query: 360  KMAMSLILRRFSFELSPSYVHAPFTLITMQPQYGAHLILHKL 235
            K+ +++IL+RF F+++PSYVHAPFT++T+QPQ+G+H+I  KL
Sbjct: 481  KLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFGSHVIYKKL 522