BLASTX nr result
ID: Bupleurum21_contig00002104
seq
BLASTX 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Bupleurum21_contig00002104
(1158 letters)
Database: ./nr
23,641,837 sequences; 8,123,359,852 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
ref|XP_003517554.1| PREDICTED: uncharacterized protein LOC100795... 328 1e-87
ref|XP_002319250.1| predicted protein [Populus trichocarpa] gi|2... 328 1e-87
ref|XP_002270776.2| PREDICTED: uncharacterized protein LOC100249... 325 2e-86
emb|CBI26484.3| unnamed protein product [Vitis vinifera] 325 2e-86
ref|XP_003537726.1| PREDICTED: uncharacterized protein LOC100803... 324 2e-86
>ref|XP_003517554.1| PREDICTED: uncharacterized protein LOC100795783 [Glycine max]
Length = 859
Score = 328 bits (842), Expect = 1e-87
Identities = 188/369 (50%), Positives = 261/369 (70%), Gaps = 7/369 (1%)
Frame = +2
Query: 71 RDFELEANNYSKMVMELKS---EIETLRQELEKA-DGYVEKLAKTEVAVQQLNVDLQSAK 238
++ E N ++ V L S E++ ++QEL D + L+ + A + + ++ A+
Sbjct: 190 KELESVRNQHALDVSALLSTTQELQQIKQELAMTCDAKNQALSHADDATKIAELHVEKAE 249
Query: 239 L--AEACAQEKVKDYEVEASTYRN-IVMELKSEVETLKEKLEKANDLERKVVENETALEQ 409
+ AE + V D ++E N +V+EL++E+E LKE+LEKA + K+ E E +EQ
Sbjct: 250 ILSAELIRLKAVLDSKLETEANENKVVLELQAEIEALKEELEKAQCYDAKLAEKENYIEQ 309
Query: 410 LNVELEAARMAKSYAHNLLEESQKRVEELETRVEQANRQEKSASESLDSIMRQLEESNDL 589
LNVELEAARMA+SYAH+LLEE K+VEELE RVE+AN+ E+SAS SL+S+M+QLE + DL
Sbjct: 310 LNVELEAARMAESYAHSLLEEWTKKVEELEVRVEEANKLERSASMSLESLMKQLEGNKDL 369
Query: 590 LHNAESEIASLKEKAGLMEMTLGSQRGDLEVSEQSLSMYKEQASKMAKEVESLNYELDTV 769
LH AESEI+SLKEK GL+EMT+G QRGDLE SE+ L + KE++ +++K+VESL EL+TV
Sbjct: 370 LHEAESEISSLKEKVGLLEMTIGRQRGDLEDSERCLDVAKEESLELSKKVESLESELETV 429
Query: 770 KDEKTQALNNEKLAADSVQTLLEERNKLISXXXXXXXXXXXXXXAMESLTSSLQEVSSEA 949
K+EK QALNNEKL+A SVQTLLEE++KLI+ AMESL S+L EVS+EA
Sbjct: 430 KEEKAQALNNEKLSASSVQTLLEEKDKLINELEISKDEEEKTKKAMESLASALHEVSAEA 489
Query: 950 REAKQKLLTSEDEHENLKTQVENLKLVLRASNEKYESMIEDAKREIDELTSLIQQNEHDQ 1129
R+AK+KLL + E EN +TQ+E+LKLVL+ASNEK ESM+ DA+ EID LT ++ + +
Sbjct: 490 RDAKEKLLANHVERENYETQIEDLKLVLKASNEKCESMLNDARHEIDVLTCSVENSNSNI 549
Query: 1130 QTAKADREQ 1156
+ KA+ EQ
Sbjct: 550 ENYKAEWEQ 558
Score = 62.8 bits (151), Expect = 2e-07
Identities = 89/387 (22%), Positives = 163/387 (42%), Gaps = 25/387 (6%)
Frame = +2
Query: 71 RDFELEANNYSKMVMELK--SEIETLRQELEKADGYVEKLAKTEVAVQQLNVDLQSAKLA 244
++ L A S + K +E ++ R AD + ++AK QLN+ + K A
Sbjct: 58 QNLRLSAEKSSPRALNSKPATERKSPRPTSTAADKQLPRVAKGSELQAQLNLAQEDLKKA 117
Query: 245 EACAQEKVKDYEVEASTYRNIVMELKSEVETLKEKLEKANDLERKVVENETALEQLNVEL 424
+ E++ E E + + E + E EKL +A +++ E+ + VEL
Sbjct: 118 K----EQLIQAEKEKEKAIDELKEAQRVAEEANEKLREAMVAQKRAEESSEIEKFRAVEL 173
Query: 425 EAARMAKSYAHNLLEESQKRVEELETRVEQANRQEKSASESLDSIMRQL----EESNDLL 592
E A + H EE QK +E + + S ++ L I ++L + N L
Sbjct: 174 EQAGI--EAVHKKEEEWQKELESVRNQHALDVSALLSTTQELQQIKQELAMTCDAKNQAL 231
Query: 593 HNAE--SEIASLK-EKAGLMEMTLGSQRGDLEVSEQSLSMYKEQASKMAKEVESLNYELD 763
+A+ ++IA L EKA ++ L + L+ ++ + + ++ E+E+L EL+
Sbjct: 232 SHADDATKIAELHVEKAEILSAELIRLKAVLDSKLETEANENKVVLELQAEIEALKEELE 291
Query: 764 TV---------KDEKTQALNNE----KLAADSVQTLLEERNKLISXXXXXXXXXXXXXXA 904
K+ + LN E ++A +LLEE K +
Sbjct: 292 KAQCYDAKLAEKENYIEQLNVELEAARMAESYAHSLLEEWTKKVEELEVRVEEANKLE-- 349
Query: 905 MESLTSSLQEVSSEAREAKQKLLTSEDEHENLKTQVENLKLVL---RASNEKYESMIEDA 1075
S + SL+ + + K L +E E +LK +V L++ + R E E ++ A
Sbjct: 350 -RSASMSLESLMKQLEGNKDLLHEAESEISSLKEKVGLLEMTIGRQRGDLEDSERCLDVA 408
Query: 1076 KREIDELTSLIQQNEHDQQTAKADREQ 1156
K E EL+ ++ E + +T K ++ Q
Sbjct: 409 KEESLELSKKVESLESELETVKEEKAQ 435
>ref|XP_002319250.1| predicted protein [Populus trichocarpa] gi|222857626|gb|EEE95173.1|
predicted protein [Populus trichocarpa]
Length = 713
Score = 328 bits (842), Expect = 1e-87
Identities = 179/354 (50%), Positives = 257/354 (72%), Gaps = 5/354 (1%)
Frame = +2
Query: 110 VMELKSEIETLRQELEK-ADGYVEKLAKTEVAVQQLNVDLQSAKL--AEACAQEKVKD-- 274
++ E++ L+QEL D + L+ + A + + + ++ +E + D
Sbjct: 191 LLSTTQELQRLKQELAMITDAKNQALSHADDATKIAEIHAEKVEMLSSELTRLNVLLDSK 250
Query: 275 YEVEASTYRNIVMELKSEVETLKEKLEKANDLERKVVENETALEQLNVELEAARMAKSYA 454
E EA IV++L E+++LK++LEK+ D E K++E E +EQLNVELEAA+MA+SYA
Sbjct: 251 LETEAIESNKIVLQLNEEIDSLKQQLEKSEDFEDKLIEREAFIEQLNVELEAAKMAESYA 310
Query: 455 HNLLEESQKRVEELETRVEQANRQEKSASESLDSIMRQLEESNDLLHNAESEIASLKEKA 634
NL+EE + RVEELE + E+AN+ E+SASESL S+M+QLE +NDLLH+AE+EIA+LKEK
Sbjct: 311 CNLVEEWKNRVEELEMQAEEANKLERSASESLGSVMKQLEANNDLLHDAETEIAALKEKV 370
Query: 635 GLMEMTLGSQRGDLEVSEQSLSMYKEQASKMAKEVESLNYELDTVKDEKTQALNNEKLAA 814
GL+EMT+ Q+GDLE SE SL M KE+AS M K+VESL EL+TVK+EK QALNNEKLAA
Sbjct: 371 GLLEMTIRRQKGDLEESEHSLGMVKEEASVMVKKVESLMSELETVKEEKAQALNNEKLAA 430
Query: 815 DSVQTLLEERNKLISXXXXXXXXXXXXXXAMESLTSSLQEVSSEAREAKQKLLTSEDEHE 994
SVQ+LLEE+NKLI+ AMESL S+L EVS+EAREAK++L++++ EHE
Sbjct: 431 SSVQSLLEEKNKLITELENSRDEEEKSKKAMESLASALHEVSAEAREAKERLVSNQVEHE 490
Query: 995 NLKTQVENLKLVLRASNEKYESMIEDAKREIDELTSLIQQNEHDQQTAKADREQ 1156
N +TQ+E+L+LVL+A+NEKYE++++DAK EID L + ++++++ Q +KA+ +Q
Sbjct: 491 NYETQIEDLRLVLKATNEKYETVLDDAKHEIDLLRNTVEESKNQFQNSKAEWDQ 544
>ref|XP_002270776.2| PREDICTED: uncharacterized protein LOC100249386 [Vitis vinifera]
Length = 846
Score = 325 bits (832), Expect = 2e-86
Identities = 178/354 (50%), Positives = 257/354 (72%), Gaps = 5/354 (1%)
Frame = +2
Query: 110 VMELKSEIETLRQELEK-ADGYVEKLAKTEVAVQQLNVDLQSAKL--AEACAQEKVKDY- 277
++ E++ ++QEL +D + L+ + A + + + A++ AE + + D
Sbjct: 189 LLSATQELQRMKQELAMTSDAKNQALSHADDATKIAEIHAEKAEILSAELTRLKALLDSK 248
Query: 278 -EVEASTYRNIVMELKSEVETLKEKLEKANDLERKVVENETALEQLNVELEAARMAKSYA 454
E EA+ +V L SE+++LK++LE+A E + E E ++EQLNV+LEAARMA+SYA
Sbjct: 249 NETEANENSKMVAALNSEIDSLKQELEEAKASEEALAEREASIEQLNVDLEAARMAESYA 308
Query: 455 HNLLEESQKRVEELETRVEQANRQEKSASESLDSIMRQLEESNDLLHNAESEIASLKEKA 634
NL++E ++RVEELETRVE+A R EKSA+ESLDS+M+QLE +N LLH+AESEIA+LKEK
Sbjct: 309 RNLVQEWKQRVEELETRVEEATRLEKSATESLDSVMQQLEGNNGLLHDAESEIAALKEKV 368
Query: 635 GLMEMTLGSQRGDLEVSEQSLSMYKEQASKMAKEVESLNYELDTVKDEKTQALNNEKLAA 814
GL+E+++G Q+GD E SE+ L + K++AS+M K VESL EL+T+K+EK QALNNEKLAA
Sbjct: 369 GLLEISIGRQKGDFEESERRLEVAKQEASEMGKMVESLKAELETLKEEKAQALNNEKLAA 428
Query: 815 DSVQTLLEERNKLISXXXXXXXXXXXXXXAMESLTSSLQEVSSEAREAKQKLLTSEDEHE 994
SVQ LLEE+NKL++ AMESL S+L EVSSEAREAK+KLL ++ E E
Sbjct: 429 SSVQNLLEEKNKLLNDLENSKDEEEKSKKAMESLASALHEVSSEAREAKEKLLAAQGEQE 488
Query: 995 NLKTQVENLKLVLRASNEKYESMIEDAKREIDELTSLIQQNEHDQQTAKADREQ 1156
TQ+E+LK+VL+A+NEKYE++++DAK E++ LTS I+Q++ + +T+KA+ EQ
Sbjct: 489 MYDTQIEDLKMVLKATNEKYETLLDDAKHEVELLTSTIEQSKREFETSKAEWEQ 542
Score = 58.5 bits (140), Expect = 3e-06
Identities = 84/368 (22%), Positives = 155/368 (42%), Gaps = 34/368 (9%)
Frame = +2
Query: 155 EKADGYVEKLAKTEVAVQQLNVDLQSAKLAEACAQEKVKDYEVEASTYRNIVMELKSEVE 334
EK V K ++ + + DL+ AK + EK K ++ + E + E
Sbjct: 74 EKPQSRVLKGSELQAQLSHAQEDLKKAK-EQLVIAEKEKVQAIDE------LKEAQKSAE 126
Query: 335 TLKEKLEKANDLERKVVENETALEQLNVELEAARMAKSYAHNLLEESQKRVEELETRVEQ 514
EKL +A +++ EN + VE+E A +E +QK+ +E + +E
Sbjct: 127 EANEKLREALVAQKRAEENSEIEKFRAVEMEQAG---------IEAAQKKEDEWQKELES 177
Query: 515 ANRQEK-------SASESLDSIMRQLEESNDLLHNAES------EIASL-KEKAGLMEMT 652
Q SA++ L + ++L ++D + A S +IA + EKA ++
Sbjct: 178 VRSQHALDVAALLSATQELQRMKQELAMTSDAKNQALSHADDATKIAEIHAEKAEILSAE 237
Query: 653 LGSQRGDLEVSEQSLSMYKEQASKMAKEVESLNYELDTVKDEKTQALNNEKLAAD---SV 823
L + L+ S + +A++ +K V +LN E+D++K E +A +E+ A+ S+
Sbjct: 238 LTRLKALLD------SKNETEANENSKMVAALNSEIDSLKQELEEAKASEEALAEREASI 291
Query: 824 QTL---LEERNKLISXXXXXXXXXXXXXXAME-----------SLTSSLQEVSSEAREAK 961
+ L LE S +E S T SL V +
Sbjct: 292 EQLNVDLEAARMAESYARNLVQEWKQRVEELETRVEEATRLEKSATESLDSVMQQLEGNN 351
Query: 962 QKLLTSEDEHENLKTQVENLKLVL---RASNEKYESMIEDAKREIDELTSLIQQNEHDQQ 1132
L +E E LK +V L++ + + E+ E +E AK+E E+ +++ + + +
Sbjct: 352 GLLHDAESEIAALKEKVGLLEISIGRQKGDFEESERRLEVAKQEASEMGKMVESLKAELE 411
Query: 1133 TAKADREQ 1156
T K ++ Q
Sbjct: 412 TLKEEKAQ 419
>emb|CBI26484.3| unnamed protein product [Vitis vinifera]
Length = 825
Score = 325 bits (832), Expect = 2e-86
Identities = 178/354 (50%), Positives = 257/354 (72%), Gaps = 5/354 (1%)
Frame = +2
Query: 110 VMELKSEIETLRQELEK-ADGYVEKLAKTEVAVQQLNVDLQSAKL--AEACAQEKVKDY- 277
++ E++ ++QEL +D + L+ + A + + + A++ AE + + D
Sbjct: 189 LLSATQELQRMKQELAMTSDAKNQALSHADDATKIAEIHAEKAEILSAELTRLKALLDSK 248
Query: 278 -EVEASTYRNIVMELKSEVETLKEKLEKANDLERKVVENETALEQLNVELEAARMAKSYA 454
E EA+ +V L SE+++LK++LE+A E + E E ++EQLNV+LEAARMA+SYA
Sbjct: 249 NETEANENSKMVAALNSEIDSLKQELEEAKASEEALAEREASIEQLNVDLEAARMAESYA 308
Query: 455 HNLLEESQKRVEELETRVEQANRQEKSASESLDSIMRQLEESNDLLHNAESEIASLKEKA 634
NL++E ++RVEELETRVE+A R EKSA+ESLDS+M+QLE +N LLH+AESEIA+LKEK
Sbjct: 309 RNLVQEWKQRVEELETRVEEATRLEKSATESLDSVMQQLEGNNGLLHDAESEIAALKEKV 368
Query: 635 GLMEMTLGSQRGDLEVSEQSLSMYKEQASKMAKEVESLNYELDTVKDEKTQALNNEKLAA 814
GL+E+++G Q+GD E SE+ L + K++AS+M K VESL EL+T+K+EK QALNNEKLAA
Sbjct: 369 GLLEISIGRQKGDFEESERRLEVAKQEASEMGKMVESLKAELETLKEEKAQALNNEKLAA 428
Query: 815 DSVQTLLEERNKLISXXXXXXXXXXXXXXAMESLTSSLQEVSSEAREAKQKLLTSEDEHE 994
SVQ LLEE+NKL++ AMESL S+L EVSSEAREAK+KLL ++ E E
Sbjct: 429 SSVQNLLEEKNKLLNDLENSKDEEEKSKKAMESLASALHEVSSEAREAKEKLLAAQGEQE 488
Query: 995 NLKTQVENLKLVLRASNEKYESMIEDAKREIDELTSLIQQNEHDQQTAKADREQ 1156
TQ+E+LK+VL+A+NEKYE++++DAK E++ LTS I+Q++ + +T+KA+ EQ
Sbjct: 489 MYDTQIEDLKMVLKATNEKYETLLDDAKHEVELLTSTIEQSKREFETSKAEWEQ 542
Score = 58.5 bits (140), Expect = 3e-06
Identities = 84/368 (22%), Positives = 155/368 (42%), Gaps = 34/368 (9%)
Frame = +2
Query: 155 EKADGYVEKLAKTEVAVQQLNVDLQSAKLAEACAQEKVKDYEVEASTYRNIVMELKSEVE 334
EK V K ++ + + DL+ AK + EK K ++ + E + E
Sbjct: 74 EKPQSRVLKGSELQAQLSHAQEDLKKAK-EQLVIAEKEKVQAIDE------LKEAQKSAE 126
Query: 335 TLKEKLEKANDLERKVVENETALEQLNVELEAARMAKSYAHNLLEESQKRVEELETRVEQ 514
EKL +A +++ EN + VE+E A +E +QK+ +E + +E
Sbjct: 127 EANEKLREALVAQKRAEENSEIEKFRAVEMEQAG---------IEAAQKKEDEWQKELES 177
Query: 515 ANRQEK-------SASESLDSIMRQLEESNDLLHNAES------EIASL-KEKAGLMEMT 652
Q SA++ L + ++L ++D + A S +IA + EKA ++
Sbjct: 178 VRSQHALDVAALLSATQELQRMKQELAMTSDAKNQALSHADDATKIAEIHAEKAEILSAE 237
Query: 653 LGSQRGDLEVSEQSLSMYKEQASKMAKEVESLNYELDTVKDEKTQALNNEKLAAD---SV 823
L + L+ S + +A++ +K V +LN E+D++K E +A +E+ A+ S+
Sbjct: 238 LTRLKALLD------SKNETEANENSKMVAALNSEIDSLKQELEEAKASEEALAEREASI 291
Query: 824 QTL---LEERNKLISXXXXXXXXXXXXXXAME-----------SLTSSLQEVSSEAREAK 961
+ L LE S +E S T SL V +
Sbjct: 292 EQLNVDLEAARMAESYARNLVQEWKQRVEELETRVEEATRLEKSATESLDSVMQQLEGNN 351
Query: 962 QKLLTSEDEHENLKTQVENLKLVL---RASNEKYESMIEDAKREIDELTSLIQQNEHDQQ 1132
L +E E LK +V L++ + + E+ E +E AK+E E+ +++ + + +
Sbjct: 352 GLLHDAESEIAALKEKVGLLEISIGRQKGDFEESERRLEVAKQEASEMGKMVESLKAELE 411
Query: 1133 TAKADREQ 1156
T K ++ Q
Sbjct: 412 TLKEEKAQ 419
>ref|XP_003537726.1| PREDICTED: uncharacterized protein LOC100803802 [Glycine max]
Length = 861
Score = 324 bits (831), Expect = 2e-86
Identities = 179/353 (50%), Positives = 253/353 (71%), Gaps = 4/353 (1%)
Frame = +2
Query: 110 VMELKSEIETLRQELEKA-DGYVEKLAKTEVAVQQLNVDLQSAKL--AEACAQEKVKDYE 280
++ E++ ++QEL D + L+ + A + + ++ A++ E + V D +
Sbjct: 206 LLSTTQELQRIKQELAMTCDAKNQALSHADDATKIAELHVEKAEILSVELIRLKAVLDSK 265
Query: 281 VEASTY-RNIVMELKSEVETLKEKLEKANDLERKVVENETALEQLNVELEAARMAKSYAH 457
+E NIV+EL++E+E LKE+LEKA + K+ E E +EQLNV+LEAARMA+SYAH
Sbjct: 266 LETEAIANNIVLELQAEIEALKEELEKAKGYDAKLAEKENYIEQLNVDLEAARMAESYAH 325
Query: 458 NLLEESQKRVEELETRVEQANRQEKSASESLDSIMRQLEESNDLLHNAESEIASLKEKAG 637
+LLEE K+VEELE RVE+AN+ E+SAS SL+S+M+QLE + DLLH AESEI+SLKEK G
Sbjct: 326 SLLEEWTKKVEELEVRVEEANKLERSASVSLESVMKQLEVNKDLLHEAESEISSLKEKVG 385
Query: 638 LMEMTLGSQRGDLEVSEQSLSMYKEQASKMAKEVESLNYELDTVKDEKTQALNNEKLAAD 817
L+EMT+ Q GDLE SE L + KE++ +++K+VESL EL+TVK+EK ALNNEKL+A
Sbjct: 386 LLEMTIARQTGDLEDSECCLHVAKEESLELSKKVESLESELETVKEEKALALNNEKLSAS 445
Query: 818 SVQTLLEERNKLISXXXXXXXXXXXXXXAMESLTSSLQEVSSEAREAKQKLLTSEDEHEN 997
SVQTLLEE++KLI+ AMESL S+L EVS+EAR++K+KLL + EHEN
Sbjct: 446 SVQTLLEEKDKLINELEILRDEEEKTKKAMESLASALHEVSAEARDSKEKLLANHVEHEN 505
Query: 998 LKTQVENLKLVLRASNEKYESMIEDAKREIDELTSLIQQNEHDQQTAKADREQ 1156
+TQ+E+LKLVL+A+NEKYESM+ DA+ EID LT ++ ++ + + +KA+ EQ
Sbjct: 506 YETQIEDLKLVLKATNEKYESMLNDARHEIDTLTCSVENSKSNIENSKAEWEQ 558
Score = 58.5 bits (140), Expect = 3e-06
Identities = 80/359 (22%), Positives = 146/359 (40%), Gaps = 30/359 (8%)
Frame = +2
Query: 164 DGYVEKLAKTEVAVQQLNVDLQSAKLAEACAQEKVKDYEVEASTYRNIVMELKSEVETLK 343
D + ++AK QLN+ + K A+ E++ E E + E + E
Sbjct: 91 DKQIPRVAKGSELQAQLNLAQEDLKKAK----EQLVQAEKEKEKAIGELKEAQRVAEEAN 146
Query: 344 EKLEKANDLERKVVENETALEQLNVELEAARMAKSYAHNLLEESQKRVEELETRVEQANR 523
EKL +A +++ E+ + VELE A +E +QK+ EE + +E
Sbjct: 147 EKLSEAIVAQKRAEESSEIEKFRAVELEQAG---------IEAAQKKEEEWQEELESVRN 197
Query: 524 QEK-------SASESLDSIMRQL----EESNDLLHNAE--SEIASLK-EKAGLMEMTLGS 661
Q S ++ L I ++L + N L +A+ ++IA L EKA ++ + L
Sbjct: 198 QHALDVSALLSTTQELQRIKQELAMTCDAKNQALSHADDATKIAELHVEKAEILSVELIR 257
Query: 662 QRGDLEVSEQSLSMYKEQASKMAKEVESLNYELDTVKDEKTQALNNE------------- 802
+ L+ ++ ++ ++ E+E+L EL+ K + E
Sbjct: 258 LKAVLDSKLETEAIANNIVLELQAEIEALKEELEKAKGYDAKLAEKENYIEQLNVDLEAA 317
Query: 803 KLAADSVQTLLEERNKLISXXXXXXXXXXXXXXAMESLTSSLQEVSSEAREAKQKLLTSE 982
++A +LLEE K + S + SL+ V + K L +E
Sbjct: 318 RMAESYAHSLLEEWTKKVEELEVRVEEANKLE---RSASVSLESVMKQLEVNKDLLHEAE 374
Query: 983 DEHENLKTQVENLKLVLRASN---EKYESMIEDAKREIDELTSLIQQNEHDQQTAKADR 1150
E +LK +V L++ + E E + AK E EL+ ++ E + +T K ++
Sbjct: 375 SEISSLKEKVGLLEMTIARQTGDLEDSECCLHVAKEESLELSKKVESLESELETVKEEK 433