BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Atropa21_contig00019027
         (1828 letters)

Database: ./nr 
           37,332,560 sequences; 13,225,080,153 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_004241385.1| PREDICTED: cytochrome P450 82C2-like [Solanu...   934   0.0  
gb|ABC69375.1| CYP82M1v4 [Nicotiana tabacum]                          508   e-141
gb|ABC69376.1| CYP82M1v5 [Nicotiana tabacum]                          507   e-141
gb|ABC69374.1| CYP82M1v3 [Nicotiana tabacum]                          506   e-140
gb|ABC69373.1| CYP82M1v2 [Nicotiana tabacum]                          504   e-140
gb|ABC69372.1| CYP82M1v1 [Nicotiana tabacum]                          503   e-139
ref|XP_006349946.1| PREDICTED: cytochrome P450 82C2-like [Solanu...   502   e-139
ref|XP_006339196.1| PREDICTED: cytochrome P450 82C4-like [Solanu...   484   e-134
ref|XP_006352674.1| PREDICTED: cytochrome P450 82C4-like [Solanu...   482   e-133
ref|XP_004248527.1| PREDICTED: cytochrome P450 82C2-like, partia...   481   e-133
ref|XP_004249377.1| PREDICTED: cytochrome P450 82C4-like [Solanu...   476   e-131
gb|ADP65810.1| nicotine N-demethylase [Nicotiana sylvestris]          475   e-131
dbj|BAM36724.1| nicotine N-demethylase [Nicotiana alata]              473   e-131
gb|ADP65809.1| nicotine N-demethylase [Nicotiana tabacum]             473   e-131
gb|ABD39479.1| CYP82E4v8 [Nicotiana tabacum]                          473   e-130
dbj|BAM36723.1| nicotine N-demethylase [Nicotiana alata]              473   e-130
gb|ABD39478.1| CYP82E4v7 [Nicotiana tabacum]                          472   e-130
gb|ABD39477.1| CYP82E4v6 [Nicotiana tabacum]                          472   e-130
gb|ABD39481.1| CYP82E4v11 [Nicotiana tabacum]                         471   e-130
gb|ABA07804.1| cytochrome P450 monooxygenase CYP82E4v2 [Nicotian...   471   e-130

>ref|XP_004241385.1| PREDICTED: cytochrome P450 82C2-like [Solanum lycopersicum]
          Length = 543

 Score =  934 bits (2413), Expect = 0.0
 Identities = 461/547 (84%), Positives = 485/547 (88%)
 Frame = +3

Query: 87   MDFHILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNN 266
            M+ HILSH EAI+GILVF FL FL RK KT+KNSKKFG  PP+LPGAWPIIGHLPQIL+N
Sbjct: 1    MEIHILSHVEAIIGILVFFFLLFLIRKAKTWKNSKKFGPAPPQLPGAWPIIGHLPQILSN 60

Query: 267  TLDGRSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNL 446
            TLDGR+R N DGEIPLAHTL ALADKYGPVFTVRQGMF IAVVSSYEAIKECFTTQDKNL
Sbjct: 61   TLDGRNRINKDGEIPLAHTLGALADKYGPVFTVRQGMFPIAVVSSYEAIKECFTTQDKNL 120

Query: 447  ANRVATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSI 626
            ANRVATCSCKYLGYDHANLTFANYGPYWRMVR             ERLKHVRI+EVESSI
Sbjct: 121  ANRVATCSCKYLGYDHANLTFANYGPYWRMVRKLVVNNLLSSKSLERLKHVRISEVESSI 180

Query: 627  KELYTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXX 806
            KELYTLFVAN+AKN PTKVDIGHWFDDMMLNITVKMIGGKRYSQV++K            
Sbjct: 181  KELYTLFVANEAKNVPTKVDIGHWFDDMMLNITVKMIGGKRYSQVNNKEEEKEEAERFRK 240

Query: 807  XXNETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKIN 986
              NETMYY+A+VGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRK N
Sbjct: 241  AFNETMYYIAIVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKNN 300

Query: 987  ESSGTGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWII 1166
            ES+   +          MLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWII
Sbjct: 301  ESNDDQD------LIDIMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWII 354

Query: 1167 ACLLSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLVHEAL 1346
            ACLL+NKHVL+KV EEIDTKVG+DRWVEDSDIKNL+YFQATIKEVLRLYPPSPMLVHEAL
Sbjct: 355  ACLLNNKHVLEKVHEEIDTKVGKDRWVEDSDIKNLMYFQATIKEVLRLYPPSPMLVHEAL 414

Query: 1347 ADCQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPF 1526
            ADCQVLGYHI KGTRLFVNVWKLQKD KFWPEPEKFLPERFLT K KVDVYGKDLEFIPF
Sbjct: 415  ADCQVLGYHISKGTRLFVNVWKLQKDSKFWPEPEKFLPERFLTTKAKVDVYGKDLEFIPF 474

Query: 1527 GSGRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKP 1706
            GSGRR+CPGITMAMQVTYLSIARLLQAFDF+ P+N P+DMTEGPGFTAVKK PLEVVVKP
Sbjct: 475  GSGRRSCPGITMAMQVTYLSIARLLQAFDFDLPNNDPLDMTEGPGFTAVKKVPLEVVVKP 534

Query: 1707 RMIPVYY 1727
            RM+P+YY
Sbjct: 535  RMLPMYY 541


>gb|ABC69375.1| CYP82M1v4 [Nicotiana tabacum]
          Length = 521

 Score =  508 bits (1309), Expect = e-141
 Identities = 259/545 (47%), Positives = 354/545 (64%), Gaps = 3/545 (0%)
 Frame = +3

Query: 87   MDFHILSHDEAIVGILVFAFL-FFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILN 263
            MD+HI  H +A++G+L F FL   L R+T T   S+K     PE+PGAWPIIGHL Q+  
Sbjct: 1    MDYHISFHFQALLGLLAFVFLSIILWRRTLT---SRKLA---PEIPGAWPIIGHLRQL-- 52

Query: 264  NTLDGRSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKN 443
                    S TD  IP    L ALADKYGPVFT+R GM+   +V+++EA K+C TT DK+
Sbjct: 53   --------SGTDKNIPFPRILGALADKYGPVFTLRIGMYPYLIVNNWEAAKDCLTTHDKD 104

Query: 444  LANRVATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESS 623
            LA R  + + + +GY +A  T+AN+GPY+  VR             E++KH+R++E+E+S
Sbjct: 105  LAARPTSMAGESIGYKYARFTYANFGPYYNQVRKLALQHVLSSTKLEKMKHIRVSELETS 164

Query: 624  IKELYTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXX 803
            IKELY+L +    KN   KV+I  WF+ + LNI VK I GKRYS + +            
Sbjct: 165  IKELYSLTLG---KNNMQKVNISKWFEQLTLNIIVKTICGKRYSNIEEDEEAQRFRKAFK 221

Query: 804  XXXNETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKI 983
                  M+ +  + + DA PFPL ++ D QG+I++M +I  ++D ILQ WLDDH   + +
Sbjct: 222  GI----MFVVGQIVLYDAIPFPLFKYFDFQGHIQLMNKIYKDLDSILQGWLDDHMMNKDV 277

Query: 984  NESSGTGNXXXXXXXXXXMLTELDKDDFQ-YGYSRETIIKATMLTIVSDATHTTAVHLIW 1160
            N                 ML     ++F+ YG+S+ T+IK+T+L+++ D   TTAVHLIW
Sbjct: 278  NNKDQDA--------IDAMLKVTQLNEFKAYGFSQATVIKSTVLSLILDGNDTTAVHLIW 329

Query: 1161 IIACLLSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-H 1337
            +++ LL+N HV+K+ QEEID KVG++RW+ED+DIKNLVY QA +KE LRLYPP P L+ H
Sbjct: 330  VMSLLLNNPHVMKQGQEEIDMKVGKERWIEDTDIKNLVYLQAIVKETLRLYPPVPFLLPH 389

Query: 1338 EALADCQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEF 1517
            EA+ DC+V GYHIPKGTRL++N WK+ +DP+ W EPEKF+P RFLT K  +D  G++ EF
Sbjct: 390  EAVQDCKVTGYHIPKGTRLYINAWKVHRDPEIWSEPEKFMPNRFLTSKANIDARGQNFEF 449

Query: 1518 IPFGSGRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVV 1697
            IPFGSGRR+CPGI  A  VT+L+  RLLQ FDF  P N P+DMTEG G T  K   +EV+
Sbjct: 450  IPFGSGRRSCPGIGFATLVTHLTFGRLLQGFDFSKPSNTPIDMTEGVGVTLPKVNQVEVL 509

Query: 1698 VKPRM 1712
            + PR+
Sbjct: 510  ITPRL 514


>gb|ABC69376.1| CYP82M1v5 [Nicotiana tabacum]
          Length = 521

 Score =  507 bits (1305), Expect = e-141
 Identities = 258/545 (47%), Positives = 353/545 (64%), Gaps = 3/545 (0%)
 Frame = +3

Query: 87   MDFHILSHDEAIVGILVFAFL-FFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILN 263
            MD+HI  H +A++G+L F FL   L R+T T   S+K     PE+PGAWPIIGHL Q+  
Sbjct: 1    MDYHISFHFQALLGLLAFVFLSIILWRRTLT---SRKLA---PEIPGAWPIIGHLRQL-- 52

Query: 264  NTLDGRSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKN 443
                    S TD  IP    L ALADKYGPVFT+R GM+   +V+++EA K+C TT DK+
Sbjct: 53   --------SGTDKNIPFPRILGALADKYGPVFTLRIGMYPYLIVNNWEAAKDCLTTHDKD 104

Query: 444  LANRVATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESS 623
             A R  + + + +GY +A  T+AN+GPY+  VR             E++KH+R++E+E+S
Sbjct: 105  FAARPTSMAGESIGYKYARFTYANFGPYYNQVRKLALQHVPSSTKLEKMKHIRVSELETS 164

Query: 624  IKELYTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXX 803
            IKELY+L +    KN   KV+I  WF+ + LNI VK I GKRYS + +            
Sbjct: 165  IKELYSLTLG---KNNMQKVNISKWFEQLTLNIIVKTICGKRYSNIEEDEEAQRFRKAFK 221

Query: 804  XXXNETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKI 983
                  M+ +  + + DA PFPL ++ D QG+I++M +I  ++D ILQ WLDDH   + +
Sbjct: 222  GI----MFVVGQIVLYDAIPFPLFKYFDFQGHIQLMNKIYKDLDSILQGWLDDHMMNKDV 277

Query: 984  NESSGTGNXXXXXXXXXXMLTELDKDDFQ-YGYSRETIIKATMLTIVSDATHTTAVHLIW 1160
            N                 ML     ++F+ YG+S+ T+IK+T+L+++ D   TTAVHLIW
Sbjct: 278  NNKDQDA--------IDAMLKVTQLNEFKAYGFSQATVIKSTVLSLILDGNDTTAVHLIW 329

Query: 1161 IIACLLSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-H 1337
            +++ LL+N HV+K+ QEEID KVG++RW+ED+DIKNLVY QA +KE LRLYPP P L+ H
Sbjct: 330  VMSLLLNNPHVMKQGQEEIDMKVGKERWIEDTDIKNLVYLQAIVKETLRLYPPVPFLLPH 389

Query: 1338 EALADCQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEF 1517
            EA+ DC+V GYHIPKGTRL++N WK+ +DP+ W EPEKF+P RFLT K  +D  G++ EF
Sbjct: 390  EAVQDCKVTGYHIPKGTRLYINAWKVHRDPEIWSEPEKFMPNRFLTSKANIDARGQNFEF 449

Query: 1518 IPFGSGRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVV 1697
            IPFGSGRR+CPGI  A  VT+L+  RLLQ FDF  P N P+DMTEG G T  K   +EV+
Sbjct: 450  IPFGSGRRSCPGIGFATLVTHLTFGRLLQGFDFSKPSNTPIDMTEGVGVTLPKVNQVEVL 509

Query: 1698 VKPRM 1712
            + PR+
Sbjct: 510  ITPRL 514


>gb|ABC69374.1| CYP82M1v3 [Nicotiana tabacum]
          Length = 521

 Score =  506 bits (1302), Expect = e-140
 Identities = 257/545 (47%), Positives = 353/545 (64%), Gaps = 3/545 (0%)
 Frame = +3

Query: 87   MDFHILSHDEAIVGILVFAFL-FFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILN 263
            MD+HI  H +A++G+L F FL   L R+T T   S+K     PE+PGAWPIIGHL Q+  
Sbjct: 1    MDYHISFHFQALLGLLAFVFLSIILWRRTLT---SRKLA---PEIPGAWPIIGHLRQL-- 52

Query: 264  NTLDGRSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKN 443
                    S TD  IP    L ALADKYGPVFT+R GM+   +V+++EA K+C TT DK+
Sbjct: 53   --------SGTDKNIPFPRILGALADKYGPVFTLRIGMYPYLIVNNWEAAKDCLTTHDKD 104

Query: 444  LANRVATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESS 623
             A R  + + + +GY +A  T+AN+GPY+  VR             E++KH+R++E+E+S
Sbjct: 105  FAARPTSMAGESIGYKYARFTYANFGPYYNQVRKLALQHVLSSTKLEKMKHIRVSELETS 164

Query: 624  IKELYTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXX 803
            IKELY+L +    KN   KV+I  WF+ + LNI VK I GKRYS + +            
Sbjct: 165  IKELYSLTLG---KNNMQKVNISKWFEQLTLNIIVKTICGKRYSNIEEDEEAQRFRKAFK 221

Query: 804  XXXNETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKI 983
                  M+ +  + + DA PFPL ++ D QG+I++M +I  ++D ILQ WLDDH   + +
Sbjct: 222  GI----MFVVGQIVLYDAIPFPLFKYFDFQGHIQLMNKIYKDLDSILQGWLDDHMMNKDV 277

Query: 984  NESSGTGNXXXXXXXXXXMLTELDKDDFQ-YGYSRETIIKATMLTIVSDATHTTAVHLIW 1160
            N                 ML     ++F+ YG+S+ T+IK+T+L+++ D   TTAVHLIW
Sbjct: 278  NNKDQDA--------IDAMLKVTQLNEFKAYGFSQATVIKSTVLSLILDGNDTTAVHLIW 329

Query: 1161 IIACLLSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-H 1337
            +++ LL+N HV+K+ QEEID K+G++RW+ED+DIKNLVY QA +KE LRLYPP P L+ H
Sbjct: 330  VMSLLLNNPHVMKQGQEEIDMKMGKERWIEDTDIKNLVYLQAIVKETLRLYPPVPFLLPH 389

Query: 1338 EALADCQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEF 1517
            EA+ DC+V GYHIPKGTRL++N WK+ +DP+ W EPEKF+P RFLT K  +D  G++ EF
Sbjct: 390  EAVQDCKVTGYHIPKGTRLYINAWKVHRDPEIWSEPEKFMPNRFLTSKANIDARGQNFEF 449

Query: 1518 IPFGSGRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVV 1697
            IPFGSGRR+CPGI  A  VT+L+  RLLQ FDF  P N P+DMTEG G T  K   +EV+
Sbjct: 450  IPFGSGRRSCPGIGFATLVTHLTFGRLLQGFDFSKPSNTPIDMTEGVGVTLPKVNQVEVL 509

Query: 1698 VKPRM 1712
            + PR+
Sbjct: 510  ITPRL 514


>gb|ABC69373.1| CYP82M1v2 [Nicotiana tabacum]
          Length = 521

 Score =  504 bits (1298), Expect = e-140
 Identities = 257/545 (47%), Positives = 352/545 (64%), Gaps = 3/545 (0%)
 Frame = +3

Query: 87   MDFHILSHDEAIVGILVFAFL-FFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILN 263
            MD+HI  H +A++G+L F FL   L R+T T   S+K     PE+PGAWPIIGHL Q+  
Sbjct: 1    MDYHISFHFQALLGLLAFVFLSIILWRRTLT---SRKLA---PEIPGAWPIIGHLRQL-- 52

Query: 264  NTLDGRSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKN 443
                    S TD  IP    L ALADKYGPVFT+R GM+   +V+++EA K+C TT DK+
Sbjct: 53   --------SGTDKNIPFPRILGALADKYGPVFTLRIGMYPYLIVNNWEAAKDCLTTHDKD 104

Query: 444  LANRVATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESS 623
             A R  + + + +GY +A  T+AN+GPY+  VR             E++KH+R++E+E+S
Sbjct: 105  FAARPTSMAGESIGYKYARFTYANFGPYYNQVRKLALQHVLSSTKLEKMKHIRVSELETS 164

Query: 624  IKELYTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXX 803
            IKELY+L +    KN   KV+I  WF+ + LNI VK I GKRYS + +            
Sbjct: 165  IKELYSLTLG---KNNMQKVNISKWFEQLTLNIIVKTICGKRYSNIEEDEEAQRFRKAFK 221

Query: 804  XXXNETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKI 983
                  M+ +  + + DA PFPL ++ D QG+I++M +I  ++D ILQ WLDDH   + +
Sbjct: 222  GI----MFVVGQIVLYDAIPFPLFKYFDFQGHIQLMNKIYKDLDSILQGWLDDHMMNKDV 277

Query: 984  NESSGTGNXXXXXXXXXXMLTELDKDDFQ-YGYSRETIIKATMLTIVSDATHTTAVHLIW 1160
            N                 ML     ++F+ YG+S+ T+IK+T+L+++ D   TTAVHLIW
Sbjct: 278  NNKDQDA--------IDAMLKVTQLNEFKAYGFSQATVIKSTVLSLILDGNDTTAVHLIW 329

Query: 1161 IIACLLSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-H 1337
            +++ LL+N HV+K+ QEEID KVG++RW+ED+DIKNLVY QA +KE LRL+PP P L+ H
Sbjct: 330  VMSLLLNNPHVMKQGQEEIDMKVGKERWIEDTDIKNLVYLQAIVKETLRLFPPVPFLLPH 389

Query: 1338 EALADCQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEF 1517
            EA+ DC+V GYHIPKGTRL++N WK+ +DP+ W EPEKF+P RFLT K  +D  G++ EF
Sbjct: 390  EAVQDCKVTGYHIPKGTRLYINAWKVHRDPEIWSEPEKFMPNRFLTSKANIDARGQNFEF 449

Query: 1518 IPFGSGRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVV 1697
            IPFGSGRR+CPGI  A  VT+L+  RLLQ FDF  P N P DMTEG G T  K   +EV+
Sbjct: 450  IPFGSGRRSCPGIGFATLVTHLTFGRLLQGFDFSKPSNTPTDMTEGVGVTLPKVNQVEVL 509

Query: 1698 VKPRM 1712
            + PR+
Sbjct: 510  ITPRL 514


>gb|ABC69372.1| CYP82M1v1 [Nicotiana tabacum]
          Length = 521

 Score =  503 bits (1295), Expect = e-139
 Identities = 256/545 (46%), Positives = 352/545 (64%), Gaps = 3/545 (0%)
 Frame = +3

Query: 87   MDFHILSHDEAIVGILVFAFL-FFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILN 263
            MD+HI  H +A++G+L F FL   L R+T T   S+K     PE+PGAWPIIGHL Q+  
Sbjct: 1    MDYHISFHFQALLGLLAFVFLSIILWRRTLT---SRKLA---PEIPGAWPIIGHLRQL-- 52

Query: 264  NTLDGRSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKN 443
                    S TD  IP    L ALADKYGPVFT+R GM+   +V+++EA K+C TT DK+
Sbjct: 53   --------SGTDKNIPFPRILGALADKYGPVFTLRIGMYPYLIVNNWEAAKDCLTTHDKD 104

Query: 444  LANRVATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESS 623
             A R  + + + +GY +A  T+AN+GPY+  VR             E++KH+R++E+E+S
Sbjct: 105  FAARPTSMAGESIGYKYARFTYANFGPYYNQVRKLALQHVLSSTKLEKMKHIRVSELETS 164

Query: 624  IKELYTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXX 803
            IKELY+L +    KN   KV+I  WF+ + LNI VK I GKRYS + +            
Sbjct: 165  IKELYSLTLG---KNNMQKVNISKWFEQLTLNIIVKTICGKRYSNIEEDEEAQRFRKAFK 221

Query: 804  XXXNETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKI 983
                  M+ +  + + DA PFPL ++ D QG+I++M +I  ++D ILQ WLDDH   + +
Sbjct: 222  GI----MFVVGQIVLYDAIPFPLFKYFDFQGHIQLMNKIYKDLDSILQGWLDDHMMNKDV 277

Query: 984  NESSGTGNXXXXXXXXXXMLTELDKDDFQ-YGYSRETIIKATMLTIVSDATHTTAVHLIW 1160
            N                 ML     ++F+ YG+S+ T+IK+T+L+++ D   TTAVHLIW
Sbjct: 278  NNKDQDA--------IDAMLKVTQLNEFKAYGFSQATVIKSTVLSLILDGNDTTAVHLIW 329

Query: 1161 IIACLLSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-H 1337
            +++ LL+N HV+K+ QEEID KVG++RW+ED+DIKNLVY QA +KE LRLYPP P L+ H
Sbjct: 330  VMSLLLNNPHVMKQGQEEIDMKVGKERWIEDTDIKNLVYLQAIVKETLRLYPPVPFLLPH 389

Query: 1338 EALADCQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEF 1517
            EA+ DC+V GYHIPKGTRL++N WK+ +D + W EPEKF+P RFLT K  +D  G++ EF
Sbjct: 390  EAVQDCKVTGYHIPKGTRLYINAWKVHRDSEIWSEPEKFMPNRFLTSKANIDARGQNFEF 449

Query: 1518 IPFGSGRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVV 1697
            IPFGSGRR+CPG+  A  VT+L+  RLLQ FDF  P N P+DMTEG G T  K   +EV+
Sbjct: 450  IPFGSGRRSCPGLGFATLVTHLTFGRLLQGFDFSKPSNTPIDMTEGVGVTLPKVNQVEVL 509

Query: 1698 VKPRM 1712
            + PR+
Sbjct: 510  ITPRL 514


>ref|XP_006349946.1| PREDICTED: cytochrome P450 82C2-like [Solanum tuberosum]
          Length = 531

 Score =  502 bits (1292), Expect = e-139
 Identities = 270/552 (48%), Positives = 356/552 (64%), Gaps = 4/552 (0%)
 Frame = +3

Query: 87   MDF-HILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILN 263
            M+F HI SH  AI  +L+ AF+F      K  K        PPE+ G WP+IGHL Q   
Sbjct: 1    MEFDHIFSHFNAI--LLLIAFIFSSIFIWKLLKPQNPL---PPEISGGWPVIGHLLQF-- 53

Query: 264  NTLDGRSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKN 443
                    S  D +IPL+  LA LADKYGPVFT R G+  I VVSSY+A+K+C  T DK 
Sbjct: 54   --------SGAD-DIPLSRKLATLADKYGPVFTFRLGLPCILVVSSYDAVKDCLCTNDKA 104

Query: 444  LANRVATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESS 623
             A R A+ + +Y+GY++A L  ANYGPYWR +R             E+LK VR++E+++S
Sbjct: 105  FAARPASLAGEYIGYNNAMLFLANYGPYWRKIRKIVLQEVLSSSRLEKLKFVRVSEIQTS 164

Query: 624  IKELYTLF-VANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXX 800
            I ELY+L  VA +  + P KV++ +W + + L++ VKMI GK Y +V +K          
Sbjct: 165  INELYSLISVAGENVDFPVKVNVTNWIEKLTLSLIVKMIAGKSYGRV-EKGGNEEEAERF 223

Query: 801  XXXXNETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKR- 977
                 + MY      + DAFP  L +W+D QG++K MKR   ++D +LQ WLD+H  K+ 
Sbjct: 224  KKALKDFMYISMEFVLWDAFPIALFKWIDFQGHVKFMKRTFKDIDCVLQNWLDEHLKKKE 283

Query: 978  KINESSGTGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLI 1157
            +++   G             ML+ +  +DF  G+SRET IKAT L++V DA+ TTA+HL 
Sbjct: 284  RVDVVDGNEQDFIDV-----MLSMMSNEDFADGHSRETTIKATALSMVLDASDTTAIHLN 338

Query: 1158 WIIACLLSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV- 1334
            W++A LL+++ V+KKVQEE+DTKVGR+RWVE+SDIKNLVYFQA +KE LRLYPP+P+LV 
Sbjct: 339  WVMATLLNHRDVMKKVQEELDTKVGRNRWVEESDIKNLVYFQAVVKETLRLYPPAPLLVP 398

Query: 1335 HEALADCQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLE 1514
            HE++ DC V GYHIPKGTRL+VN  KLQ+DPK W  P  F PERFLT +   DV G+  E
Sbjct: 399  HESIEDCIVQGYHIPKGTRLWVNTMKLQRDPKIWSNPNTFDPERFLTSQAGCDVRGQQYE 458

Query: 1515 FIPFGSGRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEV 1694
            FIPFGS RR+CPGIT A+QVT+L+IA LLQ FDF TP N P+DM EG G T  K  P+EV
Sbjct: 459  FIPFGSRRRSCPGITYAIQVTHLAIAHLLQGFDFSTPSNEPLDMKEGLGMTMRKVNPIEV 518

Query: 1695 VVKPRMIPVYYE 1730
            ++ PR   V Y+
Sbjct: 519  MITPRFPSVLYK 530


>ref|XP_006339196.1| PREDICTED: cytochrome P450 82C4-like [Solanum tuberosum]
          Length = 524

 Score =  484 bits (1246), Expect = e-134
 Identities = 253/538 (47%), Positives = 350/538 (65%), Gaps = 3/538 (0%)
 Frame = +3

Query: 129  ILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDGRSRSNTDGE- 305
            +LVF+    L   T+ +K++K     PPE+PG+WPIIGHL            R   DG+ 
Sbjct: 17   LLVFSLSIILW--TRNWKSTKL----PPEIPGSWPIIGHL------------RGFGDGKN 58

Query: 306  IPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANRVATCSCKYLG 485
            +PLA T   L+D+YGP+FT++ GM+   V++++EA K+CFT  DK LA R  + + ++ G
Sbjct: 59   VPLARTFGKLSDQYGPIFTIKLGMYRYCVINNWEAAKDCFTINDKELAARPISLAAEHYG 118

Query: 486  YDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKELYTLFVANQAK 665
            Y++A  +FANYGPY+  VR             E++KHVR +EVE SIKELY L    +  
Sbjct: 119  YNYARFSFANYGPYYCQVRKLVLQNVLSSTRLEKVKHVRTSEVEISIKELYNL--CGKGD 176

Query: 666  NAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXNETMYYLALVG 845
            N+ T ++I  WF+ + LNI VKMI GKRY  +                  + MY      
Sbjct: 177  NSNT-INISKWFEKLTLNIIVKMIAGKRYISLEKDEEAQCFRKAFA----KIMYLAGEFI 231

Query: 846  IEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESSGTGNXXXXXX 1025
            + DA PF + +++D QG+IK MK+I  ++D ILQ W+++H  K+KI      G+      
Sbjct: 232  LYDAIPFKIFKYVDFQGHIKTMKQIYKDLDDILQSWVNEHMEKKKIE-----GDNNNEQD 286

Query: 1026 XXXXMLTELDKDDFQ-YGYSRETIIKATMLTIVSDATHTTAVHLIWIIACLLSNKHVLKK 1202
                ML+    +DF+ YGY+R+T+IKAT+L+++ D + TTAVHL W+++ LL+N HV+  
Sbjct: 287  CIDSMLSVTKLEDFKAYGYTRDTVIKATVLSMILDGSDTTAVHLTWLMSLLLNNPHVMSH 346

Query: 1203 VQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALADCQVLGYHIP 1379
            VQ+EID KVG+DRWVE+SDIK+LVY QA +KE LRLYPP+P+LV HEA+ DC V GY+IP
Sbjct: 347  VQKEIDNKVGKDRWVEESDIKDLVYLQAIVKEALRLYPPAPLLVPHEAVEDCTVAGYNIP 406

Query: 1380 KGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGSGRRACPGIT 1559
            KGTRLF N WK+Q+DP+ + EP+KF+PERFL +   VD  G+  EFIPFGSGRR+CPGI 
Sbjct: 407  KGTRLFPNAWKIQRDPRVYSEPDKFMPERFLNEHSNVDARGQHFEFIPFGSGRRSCPGIN 466

Query: 1560 MAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRMIPVYYEV 1733
             A QV +L+I RL+Q F+F TP N PVDMTEG G T  K  P+EVV+ PR+  + YE+
Sbjct: 467  FATQVAHLTIGRLIQGFNFGTPSNLPVDMTEGQGITMPKAKPVEVVITPRLNSMLYEL 524


>ref|XP_006352674.1| PREDICTED: cytochrome P450 82C4-like [Solanum tuberosum]
          Length = 520

 Score =  482 bits (1241), Expect = e-133
 Identities = 247/540 (45%), Positives = 345/540 (63%), Gaps = 2/540 (0%)
 Frame = +3

Query: 117  AIVGILVFAFLFFLARKTKTFKNSKKFG-SPPPELPGAWPIIGHLPQILNNTLDGRSRSN 293
            AI   ++F  L+ L +     KNS K   + PPE+PGA+  IGHL   ++ T        
Sbjct: 7    AIAIFVIFVSLYMLWKTKIQAKNSSKVMINLPPEIPGAYFPIGHLYLFISKT-------- 58

Query: 294  TDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANRVATCSC 473
                 PLA  LA LADKYG +F++R G+    +VS++E +KECFTT DK LA R A+ + 
Sbjct: 59   -----PLALILANLADKYGHIFSIRLGIHRAIIVSNWEIVKECFTTNDKVLAGRPASSAG 113

Query: 474  KYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKELYTLFVA 653
             YLGY++A   FA+YGPYWR +R             ++ KH+R+ EVE++IKELY+  + 
Sbjct: 114  IYLGYNNAAFGFADYGPYWRNIRKLVLLEVLSSKRLDQFKHIRVTEVETNIKELYSSILK 173

Query: 654  NQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXNETMYYL 833
            + + N P+KV++  WF+ + LN+ +KMI GKRY    +K               E MY  
Sbjct: 174  SGSTN-PSKVNMSKWFEQLTLNVIMKMITGKRYKTEDEKGRHFTRTT------KEYMYES 226

Query: 834  ALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESSGTGNXX 1013
                + D  P P L+W D QG IK MK+++ EMD I+  W+D+H  KR++       +  
Sbjct: 227  VQFVLSDVIPLPFLKWFDFQGRIKSMKKLSQEMDKIVTSWIDEHLMKRELAIKDDDQDFI 286

Query: 1014 XXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACLLSNKHV 1193
                    ML+++D + F YGY+RETIIKAT+L I+   + TT++HL W+++ L++NKHV
Sbjct: 287  DV------MLSKID-EQFMYGYTRETIIKATILNIILAGSDTTSIHLTWLLSLLVNNKHV 339

Query: 1194 LKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALADCQVLGY 1370
            + + QEEID K+G++RWVE+ DIKNLVY QA +KE LRLYPP P+ + H A+ DC V GY
Sbjct: 340  MDQAQEEIDMKIGKERWVEECDIKNLVYLQAIVKETLRLYPPGPLAIPHAAMEDCTVGGY 399

Query: 1371 HIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGSGRRACP 1550
             +PKGTRL VNVWKL +DP+ W +PEKF+PERF+    ++D+ G++ EFIPFGSGRR+CP
Sbjct: 400  KVPKGTRLMVNVWKLHRDPQIWSDPEKFMPERFMKSHSEIDISGQNFEFIPFGSGRRSCP 459

Query: 1551 GITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRMIPVYYE 1730
            GIT AMQVT+L++ARLLQ F+F T  + PVD+T G   T  K  PLEV V PR+ P+ Y+
Sbjct: 460  GITFAMQVTHLTLARLLQGFNFSTLGDLPVDLTVGNSITLPKANPLEVFVMPRLAPMLYQ 519


>ref|XP_004248527.1| PREDICTED: cytochrome P450 82C2-like, partial [Solanum lycopersicum]
          Length = 549

 Score =  481 bits (1237), Expect = e-133
 Identities = 246/550 (44%), Positives = 343/550 (62%), Gaps = 3/550 (0%)
 Frame = +3

Query: 87   MDFHILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNN 266
            MD+H+    EAI+GIL F F   +  +      ++K     P++PGAWPIIGHL Q+   
Sbjct: 29   MDYHL----EAILGILAFVFFAIIIWRRSNTLTTEKLA---PQVPGAWPIIGHLHQL--- 78

Query: 267  TLDGRSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNL 446
                   S  D  +P AHTLAALADKYGP+FT+R GM+   +++++E  K+C TT DK+ 
Sbjct: 79   -------SGIDKNVPFAHTLAALADKYGPIFTLRMGMYPYLIINNWEGAKDCLTTHDKDF 131

Query: 447  ANRVATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSI 626
            A R  + + + +GY +A  T++N+G Y+  VR             E+++H+R+ E+E+SI
Sbjct: 132  AARPTSMAGQSIGYKYARFTYSNFGLYYNHVRKLALTQVLSSTKLEKMRHIRVVELENSI 191

Query: 627  KELYTLF-VANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXX 803
            K+LY+L  VAN+       ++I  WF  + LN  VK I GKRY+ +              
Sbjct: 192  KDLYSLTQVANKNNEV---INITQWFHQLTLNTIVKTICGKRYNNIEKDEEAKRFRKAFK 248

Query: 804  XXXNETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKI 983
                  MY +  + + D  PFPL +++D QG+IK+M  I  ++D ILQ WL+DH  K+ +
Sbjct: 249  GI----MYVVGQIVLYDVVPFPLFKYVDFQGHIKLMNNIYKDLDSILQGWLEDHMKKKDL 304

Query: 984  NESSGTGNXXXXXXXXXXMLTELDKDDFQ-YGYSRETIIKATMLTIVSDATHTTAVHLIW 1160
            N                 ML     D+F+ YGYS+ T+IK+T+L+++ D + TTAVH+IW
Sbjct: 305  NNDDDED-------AIDAMLKATYVDEFKAYGYSQATVIKSTILSLILDGSDTTAVHMIW 357

Query: 1161 IIACLLSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-H 1337
            I++ LL+N H +K+ QEEIDTKVG+ RWV +SD+KNLVY QA +KE  RLYPP P+L+ H
Sbjct: 358  IMSLLLNNPHAMKQAQEEIDTKVGKSRWVGESDVKNLVYLQAIVKETSRLYPPVPLLLPH 417

Query: 1338 EALADCQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEF 1517
            EA+ DC+V GY IPKGTR ++N WK+ +DPK W E EKF+PERFLT K  VD  G+  EF
Sbjct: 418  EAVQDCKVAGYDIPKGTRTYINAWKIHRDPKIWSESEKFMPERFLTSKSSVDARGQHFEF 477

Query: 1518 IPFGSGRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVV 1697
            IPFGSGRR+CPGI  A  VT+L+ ARLLQ F F T  N P+DMTEG G T  K   +E++
Sbjct: 478  IPFGSGRRSCPGINFATLVTHLTFARLLQGFAFSTSSNTPIDMTEGVGITLPKVNQVEIL 537

Query: 1698 VKPRMIPVYY 1727
            V PR+   +Y
Sbjct: 538  VTPRLSSNFY 547


>ref|XP_004249377.1| PREDICTED: cytochrome P450 82C4-like [Solanum lycopersicum]
          Length = 524

 Score =  476 bits (1225), Expect = e-131
 Identities = 246/538 (45%), Positives = 347/538 (64%), Gaps = 3/538 (0%)
 Frame = +3

Query: 129  ILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDGRSRSNTDGE- 305
            +LVF+    L   T+ +K++K     PP++PG+WPIIGHL            R   DGE 
Sbjct: 17   LLVFSLSIILW--TRNWKSTKL----PPKIPGSWPIIGHL------------RGFGDGEN 58

Query: 306  IPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANRVATCSCKYLG 485
            +PLA T   L+++YGP+FT++ GM+   V++++EA K+CFT  DK LA R  + + ++ G
Sbjct: 59   VPLARTFGKLSNQYGPIFTIKLGMYRYCVINNWEAAKDCFTINDKELAARPISLAAEHYG 118

Query: 486  YDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKELYTLFVANQAK 665
            Y++A  +FANYGPY+  VR             E++K+VRI+EVE SIKELY ++   +  
Sbjct: 119  YNYARFSFANYGPYYCQVRKLVLQNVLSSTRLEKVKNVRISEVEISIKELYNIWGKGENS 178

Query: 666  NAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXNETMYYLALVG 845
            N    ++I  WF+ + LNI VKMI GKRY  +                  + MY      
Sbjct: 179  NT---INISKWFEKLTLNIIVKMIAGKRYISLEKDQEAQCFRRAFA----KIMYLAGEFI 231

Query: 846  IEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESSGTGNXXXXXX 1025
            + DA PF + +++D QG+IK MK+I  ++D ILQ W+++H  K+KI      G+      
Sbjct: 232  LYDAIPFKIFKYVDFQGHIKTMKQIYKDLDDILQSWVNEHMEKKKIE-----GDNNNEQD 286

Query: 1026 XXXXMLTELDKDDFQ-YGYSRETIIKATMLTIVSDATHTTAVHLIWIIACLLSNKHVLKK 1202
                ML+    +DF+ YGY+R+T+IKA +L+++ D + TTAVHL W+++ LL+N  V+  
Sbjct: 287  CIDSMLSVTKLEDFKAYGYTRDTVIKAIVLSMILDGSDTTAVHLTWLMSLLLNNPRVMNN 346

Query: 1203 VQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALADCQVLGYHIP 1379
             Q+EID+KVG+DRW+E+SDIK+LVY QA +KE LRLYPP+P+LV HEA+ DC V GY+IP
Sbjct: 347  AQKEIDSKVGKDRWIEESDIKDLVYLQAIVKEALRLYPPAPLLVPHEAVEDCTVAGYNIP 406

Query: 1380 KGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGSGRRACPGIT 1559
            KGTRLF N WK+Q+DP+ + EP+KF+PERFL +   VD  G+  EFIPFGSGRR+CPGI 
Sbjct: 407  KGTRLFANAWKIQRDPRVYSEPDKFIPERFLNEHSNVDARGQHFEFIPFGSGRRSCPGIN 466

Query: 1560 MAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRMIPVYYEV 1733
             A QV +L+I RL+Q F F TP N PVDMTEG G T  K  P+EVV+ PR+  + YE+
Sbjct: 467  FATQVAHLTIGRLIQGFSFGTPSNLPVDMTEGQGITMPKAKPVEVVITPRLNSMLYEL 524


>gb|ADP65810.1| nicotine N-demethylase [Nicotiana sylvestris]
          Length = 517

 Score =  475 bits (1222), Expect = e-131
 Identities = 249/544 (45%), Positives = 337/544 (61%), Gaps = 1/544 (0%)
 Frame = +3

Query: 99   ILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDG 278
            ++S  EAIVG++  A LF+  R  K+ K SK     PP++PG WP+IGHL    +++ D 
Sbjct: 1    MVSPVEAIVGLVTLALLFYFIRTKKSQKPSKPL---PPKIPGGWPVIGHLFYFDDDSDDR 57

Query: 279  RSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANRV 458
                      PLA  L  LADKYGPVFT R G+  + VVSSYEAIK+CF+T D   +NR 
Sbjct: 58   ----------PLARKLGDLADKYGPVFTFRLGLPLVLVVSSYEAIKDCFSTNDAIFSNRP 107

Query: 459  ATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKELY 638
            A    +YLGY++A L    YGPYWR  R             E+LKHVR  E+++SIK LY
Sbjct: 108  AFLYGEYLGYNNAMLFLTKYGPYWRKNRKLVIQEVLCASRLEKLKHVRFGEIQTSIKNLY 167

Query: 639  TLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXNE 818
            T    N +      +++  W +++   + VKMI GK Y                      
Sbjct: 168  TRIDGNSST-----INLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFRKAFKDFIIL 222

Query: 819  TMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESSG 998
            +M ++    + DAFP PL +W+D QG++K MKR   ++D + Q WL++H  K++  E + 
Sbjct: 223  SMEFV----LWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHVKKKEKMEVNA 278

Query: 999  TGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACLL 1178
             GN          +L+++  +    GYSR+T+IKAT+ ++V DA  T A+H+ W +A L+
Sbjct: 279  EGNEQDFIDV---VLSKMSNEYLDEGYSRDTVIKATVFSLVLDAADTVALHMNWGMALLI 335

Query: 1179 SNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALADC 1355
            +N+H LKK QEEID KVG+DRWVE+SDIK+LVY Q  +KEVLRLYPP P+LV HE + DC
Sbjct: 336  NNQHALKKAQEEIDKKVGKDRWVEESDIKDLVYLQTIVKEVLRLYPPGPLLVPHENVEDC 395

Query: 1356 QVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGSG 1535
             V GYHIPKGTRLF NV KLQ+DPK W  P+KF PERF      +D  G+  EFIPFGSG
Sbjct: 396  VVSGYHIPKGTRLFANVMKLQRDPKLWSNPDKFDPERFFA--ADIDFRGQHYEFIPFGSG 453

Query: 1536 RRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRMI 1715
            RR+CPG+T AMQV +L+IA L+Q F+++TP++ P+DM EG G T  K  P+EVV+ PR+ 
Sbjct: 454  RRSCPGMTYAMQVEHLTIAHLIQGFNYKTPNDEPLDMKEGAGLTIRKVNPIEVVITPRLT 513

Query: 1716 PVYY 1727
            P  Y
Sbjct: 514  PELY 517


>dbj|BAM36724.1| nicotine N-demethylase [Nicotiana alata]
          Length = 514

 Score =  473 bits (1218), Expect = e-131
 Identities = 246/544 (45%), Positives = 339/544 (62%), Gaps = 1/544 (0%)
 Frame = +3

Query: 99   ILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDG 278
            ++S  EAIVG++   FLF+     K+ K SK     PP++PG WP+IGHL    N   DG
Sbjct: 1    MVSPIEAIVGLVTLTFLFYFLWTKKSQKPSKPL---PPKIPGGWPVIGHLFYFDN---DG 54

Query: 279  RSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANRV 458
              R       PLA  L  LADKYGPV+T R G+  + VVSSYEAIK+CF+T D   +NR 
Sbjct: 55   DDR-------PLARKLGDLADKYGPVYTFRLGLPLVLVVSSYEAIKDCFSTNDAIFSNRP 107

Query: 459  ATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKELY 638
            A    +YLGY++A L  ANYGPYWR  R             E+ KHVR+A++++ IK+LY
Sbjct: 108  AFLYGEYLGYNNAMLFLANYGPYWRKNRKLIIQEVLSASRLEKFKHVRLAKIQTGIKDLY 167

Query: 639  TLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXNE 818
            +    N +      +++  W +++   + VKMI GK Y                      
Sbjct: 168  SRIDGNSST-----INLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFKKAFKDFMIL 222

Query: 819  TMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESSG 998
            +M ++    + DAFP PL +W+D QG++K MKR   ++D + Q WL++H  KR++N    
Sbjct: 223  SMEFV----LWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHIKKREVNAEGN 278

Query: 999  TGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACLL 1178
              +          +L+++  +    GYSR+T+IKAT+ ++V DA  T A+H+ W +A L+
Sbjct: 279  EQDFIDV------VLSKMSNEYLDEGYSRDTVIKATVFSLVLDAADTVALHINWGMALLI 332

Query: 1179 SNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALADC 1355
            +N++ LKK QEEIDTKVG+DRWVE+SDIK+LVY QA +KEVLRLYPP P+LV HE + DC
Sbjct: 333  NNQNALKKAQEEIDTKVGKDRWVEESDIKDLVYLQAIVKEVLRLYPPGPLLVPHENVEDC 392

Query: 1356 QVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGSG 1535
             V GYHIPKGTRLF NV KLQ+DPK WP P+ F PERF+     +D  G+  E+IPFGSG
Sbjct: 393  VVSGYHIPKGTRLFANVMKLQRDPKLWPNPDNFDPERFVA--ANIDFRGQHYEYIPFGSG 450

Query: 1536 RRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRMI 1715
            RR+CPG+T A+QV +L++ARL+Q F++ TP   P+DM EG G T  K  P+EV++ PR+ 
Sbjct: 451  RRSCPGMTYALQVEHLTMARLIQGFNYRTPTKEPLDMKEGAGITIRKVNPVEVIITPRLA 510

Query: 1716 PVYY 1727
            P  Y
Sbjct: 511  PELY 514


>gb|ADP65809.1| nicotine N-demethylase [Nicotiana tabacum]
          Length = 517

 Score =  473 bits (1218), Expect = e-131
 Identities = 248/544 (45%), Positives = 336/544 (61%), Gaps = 1/544 (0%)
 Frame = +3

Query: 99   ILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDG 278
            ++S  EAIVG++    LF+  R  K+ K SK     PP++PG WP+IGHL    +++ D 
Sbjct: 1    MVSPVEAIVGLVTLTLLFYFIRTKKSQKPSKPL---PPKIPGGWPVIGHLFYFDDDSDDR 57

Query: 279  RSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANRV 458
                      PLA  L  LADKYGPVFT R G+  + VVSSYEAIK+CF+T D   +NR 
Sbjct: 58   ----------PLARKLGDLADKYGPVFTFRLGLPLVLVVSSYEAIKDCFSTNDAIFSNRP 107

Query: 459  ATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKELY 638
            A    +YLGY++A L    YGPYWR  R             E+LKHVR  E+++SIK LY
Sbjct: 108  AFLYGEYLGYNNAMLFLTKYGPYWRKNRKLVIQEVLCASRLEKLKHVRFGEIQTSIKNLY 167

Query: 639  TLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXNE 818
            T    N +      +++  W +++   + VKMI GK Y                      
Sbjct: 168  TRIDGNSST-----INLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFRKAFKDFIIL 222

Query: 819  TMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESSG 998
            +M ++    + DAFP PL +W+D QG++K MKR   ++D + Q WL++H  K++  E + 
Sbjct: 223  SMEFV----LWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHVKKKEKMEVNA 278

Query: 999  TGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACLL 1178
             GN          +L+++  +    GYSR+T+IKAT+ ++V DA  T A+H+ W +A L+
Sbjct: 279  EGNEQDFIDV---VLSKMSNEYLDEGYSRDTVIKATVFSLVLDAADTVALHMNWGMALLI 335

Query: 1179 SNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALADC 1355
            +N+H LKK QEEID KVG+DRWVE+SDIK+LVY Q  +KEVLRLYPP P+LV HE + DC
Sbjct: 336  NNQHALKKAQEEIDKKVGKDRWVEESDIKDLVYLQTIVKEVLRLYPPGPLLVPHENVEDC 395

Query: 1356 QVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGSG 1535
             V GYHIPKGTRLF NV KLQ+DPK W  P+KF PERF      +D  G+  EFIPFGSG
Sbjct: 396  VVSGYHIPKGTRLFANVMKLQRDPKLWSNPDKFDPERFFA--ADIDFRGQHYEFIPFGSG 453

Query: 1536 RRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRMI 1715
            RR+CPG+T AMQV +L+IA L+Q F+++TP++ P+DM EG G T  K  P+EVV+ PR+ 
Sbjct: 454  RRSCPGMTYAMQVEHLTIAHLIQGFNYKTPNDEPLDMKEGAGLTIRKVNPIEVVITPRLT 513

Query: 1716 PVYY 1727
            P  Y
Sbjct: 514  PELY 517


>gb|ABD39479.1| CYP82E4v8 [Nicotiana tabacum]
          Length = 517

 Score =  473 bits (1217), Expect = e-130
 Identities = 249/545 (45%), Positives = 339/545 (62%), Gaps = 2/545 (0%)
 Frame = +3

Query: 99   ILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDG 278
            +LS  EAIVG++ F FLFF     K+ K SK     PP++PG WP+IGHL          
Sbjct: 1    MLSPIEAIVGLVTFTFLFFFLWTKKSQKPSKPL---PPKIPGGWPVIGHLFHF------- 50

Query: 279  RSRSNTDGEI-PLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANR 455
                N DG+  PLA  L  LADKYGPVFT R G+  + VVSSYEA+K+CF+T D   +NR
Sbjct: 51   ----NDDGDDRPLARKLGDLADKYGPVFTFRLGLPLVLVVSSYEAVKDCFSTNDAIFSNR 106

Query: 456  VATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKEL 635
             A     YLGY++A L  ANYGPYWR  R             E+ KHVR A +++SIK L
Sbjct: 107  PAFLYGDYLGYNNAMLFLANYGPYWRKNRKLVIQEVLSASRLEKFKHVRFARIQASIKNL 166

Query: 636  YTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXN 815
            YT    N +      +++  W +++   + VKMI GK Y                     
Sbjct: 167  YTRIDGNSST-----INLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFKKAFKDFMI 221

Query: 816  ETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESS 995
             +M ++    + DAFP PL +W+D QG++K MKR   ++D + Q WL++H NKR+  E +
Sbjct: 222  LSMEFV----LWDAFPIPLFKWVDFQGHVKAMKRAFKDIDSVFQNWLEEHINKREKMEVN 277

Query: 996  GTGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACL 1175
              GN          +L+++  +    GYSR+T+IKAT+ ++V DA  T A+H+ W +A L
Sbjct: 278  AEGNEQDFIDV---VLSKMSNEYLGEGYSRDTVIKATVFSLVLDAADTVALHINWGMALL 334

Query: 1176 LSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALAD 1352
            ++N+  L K QEEIDTKVG+DRWVE+SDIK+LVY QA +KEVLRLYPP P+LV HE + D
Sbjct: 335  INNQKALTKAQEEIDTKVGKDRWVEESDIKDLVYLQAIVKEVLRLYPPGPLLVPHENVED 394

Query: 1353 CQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGS 1532
            C V GYHIPKGTRLFVNV KLQ+DPK W +P+ F PERF+     +D  G+  ++IPFGS
Sbjct: 395  CVVSGYHIPKGTRLFVNVMKLQRDPKLWSDPDTFDPERFIA--TDIDFRGQYYKYIPFGS 452

Query: 1533 GRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRM 1712
            GRR+CPG+T A+QV +L++A L+Q F++ TP++ P+DM EG G T  K  P+E+++ PR+
Sbjct: 453  GRRSCPGMTYALQVEHLTMAHLIQGFNYRTPNDEPLDMKEGAGITIRKVNPVELIIAPRL 512

Query: 1713 IPVYY 1727
             P  Y
Sbjct: 513  APELY 517


>dbj|BAM36723.1| nicotine N-demethylase [Nicotiana alata]
          Length = 514

 Score =  473 bits (1216), Expect = e-130
 Identities = 245/544 (45%), Positives = 339/544 (62%), Gaps = 1/544 (0%)
 Frame = +3

Query: 99   ILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDG 278
            ++S  EAIVG++   FLF+     K+ K SK     PP++PG WP+IGHL    N   DG
Sbjct: 1    MVSPIEAIVGLVTLTFLFYFLWTKKSQKPSKPL---PPKIPGGWPVIGHLFYFDN---DG 54

Query: 279  RSRSNTDGEIPLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANRV 458
              R       PLA  L  LADKYGPV+T R G+  + VVSSYEAIK+CF+T D   +NR 
Sbjct: 55   DDR-------PLARKLGDLADKYGPVYTFRLGLPLVLVVSSYEAIKDCFSTNDAIFSNRP 107

Query: 459  ATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKELY 638
            A    +YLGY++A L  ANYGP+WR  R             E+ KHVR+A++++ IK+LY
Sbjct: 108  AFLYGEYLGYNNAMLFLANYGPFWRKNRKLIIQEVLSASRLEKFKHVRLAKIQTGIKDLY 167

Query: 639  TLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXNE 818
            +    N +      +++  W +++   + VKMI GK Y                      
Sbjct: 168  SRIDGNSST-----INLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFKKAFKDFMIL 222

Query: 819  TMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESSG 998
            +M ++    + DAFP PL +W+D QG++K MKR   ++D + Q WL++H  KR++N    
Sbjct: 223  SMEFV----LWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHIKKREVNAEGN 278

Query: 999  TGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACLL 1178
              +          +L+++  +    GYSR+T+IKAT+ ++V DA  T A+H+ W +A L+
Sbjct: 279  EQDFIDV------VLSKMSNEYLDEGYSRDTVIKATVFSLVLDAADTVALHINWGMALLI 332

Query: 1179 SNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALADC 1355
            +N++ LKK QEEIDTKVG+DRWVE+SDIK+LVY QA +KEVLRLYPP P+LV HE + DC
Sbjct: 333  NNQNALKKAQEEIDTKVGKDRWVEESDIKDLVYLQAIVKEVLRLYPPGPLLVPHENVEDC 392

Query: 1356 QVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGSG 1535
             V GYHIPKGTRLF NV KLQ+DPK WP P+ F PERF+     +D  G+  E+IPFGSG
Sbjct: 393  VVSGYHIPKGTRLFANVMKLQRDPKLWPNPDNFDPERFVA--ANIDFRGQHYEYIPFGSG 450

Query: 1536 RRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRMI 1715
            RR+CPG+T A+QV +L++ARL+Q F++ TP   P+DM EG G T  K  P+EV++ PR+ 
Sbjct: 451  RRSCPGMTYALQVEHLTMARLIQGFNYRTPTKEPLDMKEGAGITICKVNPVEVIITPRLA 510

Query: 1716 PVYY 1727
            P  Y
Sbjct: 511  PELY 514


>gb|ABD39478.1| CYP82E4v7 [Nicotiana tabacum]
          Length = 517

 Score =  472 bits (1214), Expect = e-130
 Identities = 248/545 (45%), Positives = 338/545 (62%), Gaps = 2/545 (0%)
 Frame = +3

Query: 99   ILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDG 278
            +LS  EAIVG++ F FLFF     K+ K SK     PP++PG WP+IGHL          
Sbjct: 1    MLSPIEAIVGLVTFTFLFFFLWTKKSQKPSKPL---PPKIPGGWPVIGHLFHF------- 50

Query: 279  RSRSNTDGEI-PLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANR 455
                N DG+  PLA  L  LADKYGPVFT R G+  + VVSSYEA+K+CF+T D   +NR
Sbjct: 51   ----NDDGDDRPLARKLGDLADKYGPVFTFRLGLPLVLVVSSYEAVKDCFSTNDAIFSNR 106

Query: 456  VATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKEL 635
             A     YLGY++A L  ANYGPYWR  R             E+ KHVR A +++SIK L
Sbjct: 107  PAFLYGDYLGYNNAMLFLANYGPYWRKNRKLVIQEVLSASRLEKFKHVRFARIQASIKNL 166

Query: 636  YTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXN 815
            YT    N +      +++  W +++   + VKMI GK Y                     
Sbjct: 167  YTRIDGNSST-----INLTDWLEELNFGLVVKMIAGKNYESGKGDEQVERFKKAFEDFMI 221

Query: 816  ETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESS 995
             +M ++    + DAFP PL +W+D QG++K MKR   ++D + Q WL++H NKR+  E +
Sbjct: 222  LSMEFV----LWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHINKREKMEVN 277

Query: 996  GTGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACL 1175
              GN          +L+++  +    GYSR+T+IKAT+ ++V DA  T A+H+ W +A L
Sbjct: 278  AEGNEQDFIDV---VLSKMSNEYLGEGYSRDTVIKATVFSLVLDAADTVALHINWGMALL 334

Query: 1176 LSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALAD 1352
            ++N+  L K QEEIDTKVG+DRWVE+SDIK+LVY QA +KEVLRLYPP P+LV HE + D
Sbjct: 335  INNQKALTKAQEEIDTKVGKDRWVEESDIKDLVYLQAIVKEVLRLYPPGPLLVPHENVED 394

Query: 1353 CQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGS 1532
            C V GYHIPKGTRLF NV KLQ+DPK W +P+ F PERF+     +D  G+  ++IPFGS
Sbjct: 395  CVVSGYHIPKGTRLFANVMKLQRDPKLWSDPDTFDPERFIA--TDIDFRGQYYKYIPFGS 452

Query: 1533 GRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRM 1712
            GRR+CPG+T A+QV +L++A L+Q F++ TP++ P+DM EG G T  K  P+E+++ PR+
Sbjct: 453  GRRSCPGMTYALQVEHLTMAHLIQGFNYRTPNDEPLDMKEGAGITIRKVNPVELIIAPRL 512

Query: 1713 IPVYY 1727
             P  Y
Sbjct: 513  APELY 517


>gb|ABD39477.1| CYP82E4v6 [Nicotiana tabacum]
          Length = 517

 Score =  472 bits (1214), Expect = e-130
 Identities = 248/545 (45%), Positives = 338/545 (62%), Gaps = 2/545 (0%)
 Frame = +3

Query: 99   ILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDG 278
            +LS  EAIVG++ F FLFF     K+ K SK     PP++PG WP+IGHL          
Sbjct: 1    MLSPIEAIVGLVTFTFLFFFLWTKKSQKPSKPL---PPKIPGGWPVIGHLFHF------- 50

Query: 279  RSRSNTDGEI-PLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANR 455
                N DG+  PLA  L  LADKYGPVFT R G+  + VVSSYEA+K+CF+T D   +NR
Sbjct: 51   ----NDDGDDRPLARKLGDLADKYGPVFTFRLGLPLVLVVSSYEAVKDCFSTNDAIFSNR 106

Query: 456  VATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKEL 635
             A     YLGY++A L  ANYGPYWR  R             E+ KHVR A +++SIK L
Sbjct: 107  PAFLYGDYLGYNNAMLFLANYGPYWRKNRKLVIQEVLSASRLEKFKHVRFARIQASIKNL 166

Query: 636  YTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXN 815
            YT    N +      +++  W +++   + VKMI GK Y                     
Sbjct: 167  YTRIDGNSST-----INLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFKKAFKDFMI 221

Query: 816  ETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESS 995
             +M ++    + DAFP PL +W+D QG++K MKR   ++D + Q WL++H NKR+  E +
Sbjct: 222  LSMEFV----LWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHINKREKMEVN 277

Query: 996  GTGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACL 1175
              GN          +L+++  +    GYSR+T+IKAT+ ++V DA  T A+H+ W +A L
Sbjct: 278  AEGNEQDFIDV---VLSKMSNEYLGEGYSRDTVIKATVFSLVLDAADTVALHINWGMALL 334

Query: 1176 LSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALAD 1352
            ++N+  L K QEEIDTKVG+DRWVE+SDIK+LVY QA +KEVLRLYPP P+LV HE + D
Sbjct: 335  INNQKALTKAQEEIDTKVGKDRWVEESDIKDLVYLQAIVKEVLRLYPPGPLLVPHENVED 394

Query: 1353 CQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGS 1532
            C V GYHIPKGTRLF NV KL +DPK WP+P+ F PERF+     +D  G+  ++IPFGS
Sbjct: 395  CVVSGYHIPKGTRLFANVMKLLRDPKLWPDPDTFDPERFIA--TDIDFRGQYYKYIPFGS 452

Query: 1533 GRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRM 1712
            GRR+CPG+T A+QV +L++A L+Q F++ TP++ P+DM EG G T  K  P+E+++ PR+
Sbjct: 453  GRRSCPGMTYALQVEHLTMAHLIQGFNYRTPNDEPLDMKEGAGITIRKVNPVELIIAPRL 512

Query: 1713 IPVYY 1727
             P  Y
Sbjct: 513  APELY 517


>gb|ABD39481.1| CYP82E4v11 [Nicotiana tabacum]
          Length = 517

 Score =  471 bits (1213), Expect = e-130
 Identities = 249/545 (45%), Positives = 337/545 (61%), Gaps = 2/545 (0%)
 Frame = +3

Query: 99   ILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDG 278
            +LS  EAIVG++ F FLFF     K+ K SK     PP++PG WP+IGHL          
Sbjct: 1    MLSPIEAIVGLVTFTFLFFFLWTKKSQKPSKPL---PPKIPGGWPVIGHLFHF------- 50

Query: 279  RSRSNTDGEI-PLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANR 455
                N DG+  PLA  L  LADKYGPVFT R G+  + VVSSYEA+K+CF+T D   +NR
Sbjct: 51   ----NDDGDDRPLAQKLGDLADKYGPVFTFRLGLPLVLVVSSYEAVKDCFSTDDAIFSNR 106

Query: 456  VATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKEL 635
             A     YLGY++A L  ANYGPYWR  R             E+ KHVR A +++SIK L
Sbjct: 107  PAFLYGDYLGYNNAMLFLANYGPYWRKNRKLVIQEVLSASRLEKFKHVRFARIQASIKNL 166

Query: 636  YTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXN 815
            YT    N +      +++  W +++   + VKMI GK Y                     
Sbjct: 167  YTRIDGNSST-----INLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFKKAFKDFMI 221

Query: 816  ETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESS 995
             +M ++    + DAFP PL +W+D QG++K MKR   ++D + Q WL++H NKR+  E +
Sbjct: 222  LSMEFV----LWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHINKREKMEVN 277

Query: 996  GTGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACL 1175
              GN          +L+++  +    GYSR+T+IKAT+  +V DA  T A+H+ W +A L
Sbjct: 278  AEGNEQDFIDV---VLSKMSNEYLGEGYSRDTVIKATVFGLVLDAADTVALHINWGMALL 334

Query: 1176 LSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALAD 1352
            ++N+  L K QEEIDTKVG+DRWVE+SDIK+LVY QA +KEVLRLYPP P+LV HE + D
Sbjct: 335  INNQKALTKAQEEIDTKVGKDRWVEESDIKDLVYLQAIVKEVLRLYPPGPLLVPHENVED 394

Query: 1353 CQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGS 1532
            C V GYHIPKGTRLF NV KLQ+DPK W +P+ F PERF+     +D  G+  ++IPFGS
Sbjct: 395  CVVSGYHIPKGTRLFANVMKLQRDPKLWSDPDTFDPERFIA--TDIDFRGQYYKYIPFGS 452

Query: 1533 GRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRM 1712
            GRR+CPG+T A+QV +L+IA L+Q F++ TP++ P+DM EG G T  K  P+E+++ PR+
Sbjct: 453  GRRSCPGMTYALQVEHLTIAHLIQGFNYRTPNDEPLDMKEGAGITIRKVNPVELIIAPRL 512

Query: 1713 IPVYY 1727
             P  Y
Sbjct: 513  APELY 517


>gb|ABA07804.1| cytochrome P450 monooxygenase CYP82E4v2 [Nicotiana tabacum]
            gi|78214561|gb|ABB36475.1| nicotine demethylase
            [Nicotiana tabacum] gi|125489132|gb|ABN42695.1|
            cytochrome P450 CYP82E4v2 nicotine demethylase [Nicotiana
            tabacum]
          Length = 517

 Score =  471 bits (1213), Expect = e-130
 Identities = 248/545 (45%), Positives = 338/545 (62%), Gaps = 2/545 (0%)
 Frame = +3

Query: 99   ILSHDEAIVGILVFAFLFFLARKTKTFKNSKKFGSPPPELPGAWPIIGHLPQILNNTLDG 278
            +LS  EAIVG++ F FLFF     K+ K SK     PP++PG WP+IGHL          
Sbjct: 1    MLSPIEAIVGLVTFTFLFFFLWTKKSQKPSKPL---PPKIPGGWPVIGHLFHF------- 50

Query: 279  RSRSNTDGEI-PLAHTLAALADKYGPVFTVRQGMFTIAVVSSYEAIKECFTTQDKNLANR 455
                N DG+  PLA  L  LADKYGPVFT R G+  + VVSSYEA+K+CF+T D   +NR
Sbjct: 51   ----NDDGDDRPLARKLGDLADKYGPVFTFRLGLPLVLVVSSYEAVKDCFSTNDAIFSNR 106

Query: 456  VATCSCKYLGYDHANLTFANYGPYWRMVRXXXXXXXXXXXXXERLKHVRIAEVESSIKEL 635
             A     YLGY++A L  ANYGPYWR  R             E+ KHVR A +++SIK L
Sbjct: 107  PAFLYGDYLGYNNAMLFLANYGPYWRKNRKLVIQEVLSASRLEKFKHVRFARIQASIKNL 166

Query: 636  YTLFVANQAKNAPTKVDIGHWFDDMMLNITVKMIGGKRYSQVSDKXXXXXXXXXXXXXXN 815
            YT    N +      +++  W +++   + VKMI GK Y                     
Sbjct: 167  YTRIDGNSST-----INLTDWLEELNFGLIVKMIAGKNYESGKGDEQVERFKKAFKDFMI 221

Query: 816  ETMYYLALVGIEDAFPFPLLQWLDLQGNIKVMKRIADEMDVILQRWLDDHTNKRKINESS 995
             +M ++    + DAFP PL +W+D QG++K MKR   ++D + Q WL++H NKR+  E +
Sbjct: 222  LSMEFV----LWDAFPIPLFKWVDFQGHVKAMKRTFKDIDSVFQNWLEEHINKREKMEVN 277

Query: 996  GTGNXXXXXXXXXXMLTELDKDDFQYGYSRETIIKATMLTIVSDATHTTAVHLIWIIACL 1175
              GN          +L+++  +    GYSR+T+IKAT+ ++V DA  T A+H+ W +A L
Sbjct: 278  AEGNEQDFIDV---VLSKMSNEYLGEGYSRDTVIKATVFSLVLDAADTVALHINWGMALL 334

Query: 1176 LSNKHVLKKVQEEIDTKVGRDRWVEDSDIKNLVYFQATIKEVLRLYPPSPMLV-HEALAD 1352
            ++N+  L K QEEIDTKVG+DRWVE+SDIK+LVY QA +KEVLRLYPP P+LV HE + D
Sbjct: 335  INNQKALTKAQEEIDTKVGKDRWVEESDIKDLVYLQAIVKEVLRLYPPGPLLVPHENVED 394

Query: 1353 CQVLGYHIPKGTRLFVNVWKLQKDPKFWPEPEKFLPERFLTDKVKVDVYGKDLEFIPFGS 1532
            C V GYHIPKGTRLF NV KLQ+DPK W +P+ F PERF+     +D  G+  ++IPFGS
Sbjct: 395  CVVSGYHIPKGTRLFANVMKLQRDPKLWSDPDTFDPERFIA--TDIDFRGQYYKYIPFGS 452

Query: 1533 GRRACPGITMAMQVTYLSIARLLQAFDFETPDNGPVDMTEGPGFTAVKKTPLEVVVKPRM 1712
            GRR+CPG+T A+QV +L++A L+Q F++ TP++ P+DM EG G T  K  P+E+++ PR+
Sbjct: 453  GRRSCPGMTYALQVEHLTMAHLIQGFNYRTPNDEPLDMKEGAGITIRKVNPVELIIAPRL 512

Query: 1713 IPVYY 1727
             P  Y
Sbjct: 513  APELY 517