BLASTX 2.2.26 [Sep-21-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Astragalus23_contig00004279
         (3523 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           149,584,005 sequences; 54,822,741,787 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_004499912.1| PREDICTED: DNA topoisomerase 2 [Cicer arieti...   638   0.0  
gb|PNY03875.1| DNA topoisomerase 2-like protein [Trifolium prate...   632   0.0  
gb|PNY06816.1| DNA topoisomerase 2-like protein [Trifolium prate...   625   0.0  
dbj|GAU12625.1| hypothetical protein TSUD_121160 [Trifolium subt...   626   0.0  
ref|XP_015936924.1| DNA topoisomerase 2 isoform X2 [Arachis dura...   619   0.0  
ref|XP_015936922.1| DNA topoisomerase 2 isoform X1 [Arachis dura...   619   0.0  
ref|XP_016170361.1| DNA topoisomerase 2 isoform X2 [Arachis ipae...   617   0.0  
ref|XP_016170360.1| DNA topoisomerase 2 isoform X1 [Arachis ipae...   617   0.0  
ref|XP_017425524.1| PREDICTED: DNA topoisomerase 2 [Vigna angula...   609   0.0  
gb|KHN45085.1| DNA topoisomerase 2, partial [Glycine soja]            605   0.0  
ref|XP_003545986.1| PREDICTED: DNA topoisomerase 2-like [Glycine...   605   0.0  
ref|XP_014501355.1| DNA topoisomerase 2 [Vigna radiata var. radi...   601   0.0  
ref|XP_007148908.1| hypothetical protein PHAVU_005G024200g [Phas...   600   0.0  
ref|XP_003599271.2| DNA topoisomerase IV subunit A [Medicago tru...   601   0.0  
ref|XP_020212372.1| DNA topoisomerase 2 [Cajanus cajan]               595   0.0  
gb|KYP71391.1| DNA topoisomerase 2 [Cajanus cajan]                    590   0.0  
ref|XP_014618555.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...   589   0.0  
ref|XP_015952953.1| DNA topoisomerase 2-like [Arachis duranensis]     584   0.0  
ref|XP_016188028.1| DNA topoisomerase 2-like [Arachis ipaensis]       583   0.0  
sp|O24308.1|TOP2_PEA RecName: Full=DNA topoisomerase 2; AltName:...   571   e-177

>ref|XP_004499912.1| PREDICTED: DNA topoisomerase 2 [Cicer arietinum]
 ref|XP_004517303.1| PREDICTED: DNA topoisomerase 2 [Cicer arietinum]
          Length = 1472

 Score =  638 bits (1646), Expect = 0.0
 Identities = 356/611 (58%), Positives = 401/611 (65%), Gaps = 28/611 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            NAIEL  AFS+KKAEDRKT I +FEPGTFRD    L NYK+  NKELILFSRAD+QRSIP
Sbjct: 635  NAIEL--AFSKKKAEDRKTWIRNFEPGTFRDHDAKLINYKDFVNKELILFSRADLQRSIP 692

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++GMAQDFV
Sbjct: 693  SMVDGLKPGQRKILFCSFKKKLFKEIKVGQFIGYVSEHSCYHHGEQSLASTIIGMAQDFV 752

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  SR IYTEL+ VTRCLFHE+DDKL+   +EDG+SI
Sbjct: 753  GSNNINLLKPNGQFGTRNLGGKDHASSRYIYTELSAVTRCLFHEDDDKLLDYLNEDGKSI 812

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EPNWYIPIIPLVLVNG+E    GW SYIP+YNPREIIAN++ LL GE  V MDPWYRGF 
Sbjct: 813  EPNWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPREIIANVRRLLNGEAMVPMDPWYRGFR 872

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            GTIEKS KEG Y VNG+  EID +TF ITELPIR WTQDYK+FLES+T+GAPNVKDPLIE
Sbjct: 873  GTIEKSAKEGGYIVNGSVMEIDEQTFRITELPIRKWTQDYKQFLESVTDGAPNVKDPLIE 932

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI+++MKLDK   I QEGL KKFKL++TISTSNMHLFDA+GKIKKFD P
Sbjct: 933  DFRQNGDDAIVDIEVKMKLDKIATIMQEGLFKKFKLSSTISTSNMHLFDAEGKIKKFDTP 992

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEFFPLRLEYYEKRK YI           DNK RFI GV+ GEIIV          
Sbjct: 993  EQILEEFFPLRLEYYEKRKKYILANLERLLLILDNKVRFILGVVSGEIIVSNRKKADLLI 1052

Query: 2096 XXXXXGFTPMPRK-------VAGENDDNSEAEED-----------------GYEYLLSLP 2203
                 GFTPMPRK       VAG  DDNSE +ED                  YEYLLSLP
Sbjct: 1053 ELKKKGFTPMPRKGKSAEPQVAGAIDDNSEEQEDEQDTVSRPVSVEGATWGDYEYLLSLP 1112

Query: 2204 IRTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXX 2383
            I TLT                 F+ L      S                           
Sbjct: 1113 IGTLTLESVQKLRDEKAEKEKEFEILMGTPTTSLWMKDLDEFETKLDELDNKDAEDERKR 1172

Query: 2384 XXLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSMEV-GILKATPTNTLCK 2551
               +   K   NG A+KAA+KPPQP KNTKK K  EP+   +SME+   ++         
Sbjct: 1173 S--SQASKKAPNGFASKAAKKPPQPRKNTKKAKTVEPENDNSSMEIENPVEVAKPKGRAV 1230

Query: 2552 GKSVEPQVDDN 2584
             K+ + + DD+
Sbjct: 1231 SKNTQKETDDD 1241



 Score =  351 bits (900), Expect = 2e-97
 Identities = 186/277 (67%), Positives = 216/277 (77%), Gaps = 19/277 (6%)
 Frame = +2

Query: 59  MEKPPLRTSNAANIPSETF--IFREMTQREHILRHPNIYVGSMEKHTQDLWVFKKDEIVY 232
           MEK PL+TSNA NIPS+T   ++++ TQ EHIL  P+ YVGS+EKHTQ+LW+++ DE+V+
Sbjct: 1   MEKRPLQTSNATNIPSKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWIYENDEMVH 60

Query: 233 RSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEVDQE 412
           RSISYVPGLYKIFD ILV+A DNK RDPSMDSLKVTIDP  NTVSVY+N +GVP E+ QE
Sbjct: 61  RSISYVPGLYKIFDEILVNAADNKQRDPSMDSLKVTIDPEANTVSVYNNGDGVPVEIHQE 120

Query: 413 EKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLKKYK 541
           EK YVPELI                   GRNGY GAKLT IFSTE +IETADG  LKKYK
Sbjct: 121 EKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGY-GAKLTNIFSTEFVIETADGRRLKKYK 179

Query: 542 QAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAWCL 721
           Q F+NNM  +S+P IT CK +ENWTKVTFKPDLEKF+MT+LEEDVVALM+KRVLDMA CL
Sbjct: 180 QVFSNNMGNKSEPVITKCKSSENWTKVTFKPDLEKFKMTYLEEDVVALMKKRVLDMAGCL 239

Query: 722 GKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRP 832
           GK+VKVEL+G L+    I SF  Y DL MKSAEKS+P
Sbjct: 240 GKTVKVELNGTLLR---IKSFRDYADLFMKSAEKSKP 273



 Score = 77.4 bits (189), Expect = 2e-10
 Identities = 55/126 (43%), Positives = 59/126 (46%), Gaps = 21/126 (16%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQED-----------------GYEYLLSVPIRTLTFEGFLKL 2665
            KGKS EPQV    DDNSE QED                  YEYLLS+PI TLT E   KL
Sbjct: 1065 KGKSAEPQVAGAIDDNSEEQEDEQDTVSRPVSVEGATWGDYEYLLSLPIGTLTLESVQKL 1124

Query: 2666 LADKARMEKEFDILKATPTESLWMAXXXXXXXXXXXXXXXXXXXXXXXXXXQAGKKTAND 2845
              +KA  EKEF+IL  TPT SLWM                           QA KK  N 
Sbjct: 1125 RDEKAEKEKEFEILMGTPTTSLWM-KDLDEFETKLDELDNKDAEDERKRSSQASKKAPNG 1183

Query: 2846 FATKAA 2863
            FA+KAA
Sbjct: 1184 FASKAA 1189



 Score = 64.7 bits (156), Expect = 2e-06
 Identities = 30/34 (88%), Positives = 33/34 (97%)
 Frame = +2

Query: 3146 RNVGTKRTLGEKLLTDMLQPAEGTGTSPEKKVRK 3247
            RNVG K+T+G+KLLTDMLQPAEGTGTSPEKKVRK
Sbjct: 1350 RNVGGKQTMGQKLLTDMLQPAEGTGTSPEKKVRK 1383



 Score = 64.3 bits (155), Expect = 2e-06
 Identities = 32/37 (86%), Positives = 33/37 (89%)
 Frame = +3

Query: 3411 KKVRKMRESPFNKKSGSILGRAANKDKRPSEDLSSGS 3521
            KKVRKMRESPFNKKSGSILGRAANKD  P  DLS+GS
Sbjct: 1379 KKVRKMRESPFNKKSGSILGRAANKDISPIADLSAGS 1415


>gb|PNY03875.1| DNA topoisomerase 2-like protein [Trifolium pratense]
          Length = 1492

 Score =  632 bits (1630), Expect = 0.0
 Identities = 357/614 (58%), Positives = 396/614 (64%), Gaps = 30/614 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            NAIEL  AFS+KKAEDRKT I +FEPGT RD    L NYK+  NKELILFS AD+QRSIP
Sbjct: 634  NAIEL--AFSKKKAEDRKTWIRNFEPGTCRDHEAKLINYKDFVNKELILFSMADLQRSIP 691

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++GMAQDFV
Sbjct: 692  SMVDGLKPGQRKILFCSFKKKLVKEIKVGQFIGYVSEHSAYHHGEQSLASTIIGMAQDFV 751

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  SR IYTELN VTR LFHE+DDKL+   +EDGRSI
Sbjct: 752  GSNNINLLKPNGQFGTRNLGGKDHASSRYIYTELNTVTRSLFHEDDDKLLEYLNEDGRSI 811

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EP WYIPIIPLVLVNG+E    GW SYIP+YNPREI AN++ LL GE  V MDPWYRGF 
Sbjct: 812  EPTWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPREISANVRRLLNGEEMVPMDPWYRGFR 871

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            GTIEKS KEG Y VNG+  EID +TF ITELPIR WTQDYK+FLESIT+G PNVKDPLIE
Sbjct: 872  GTIEKSAKEGGYIVNGSVVEIDEQTFRITELPIRKWTQDYKQFLESITDGTPNVKDPLIE 931

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+   VDI+++MK DK   I QEGL KKFKLT TISTSNMHLFDA+G IKKFDNP
Sbjct: 932  DFRQNGDDEIVDIEVKMKADKIATIMQEGLFKKFKLTGTISTSNMHLFDAEGNIKKFDNP 991

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEFFPLRLEYYEKRK YI           DNK RFI GV+ GEIIV          
Sbjct: 992  EQILEEFFPLRLEYYEKRKKYILANLERLLLILDNKVRFILGVVNGEIIVSNRKKAELLK 1051

Query: 2096 XXXXXGFTPMPRK-------VAGENDDNSEAEEDG----------------YEYLLSLPI 2206
                 GFTPMPRK       VAG NDDNSE  EDG                YEYLLSL I
Sbjct: 1052 ELKQKGFTPMPRKGKSSEPQVAGANDDNSEEREDGEQETGTVRVEEATWGDYEYLLSLSI 1111

Query: 2207 RTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2386
             TLT                 F+ L     +S                            
Sbjct: 1112 GTLTLESVQKLLDEKAEKEKEFEILMGTPSKSLWLKDLDEFEKKLDELDSKDAEAGRKRS 1171

Query: 2387 XLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSME----VGILKATPTNTL 2545
                +     NG A+K A+KPPQP KNTKKT+N EP+   + ME    VG     P    
Sbjct: 1172 ----SQAKKNNGFASKPAKKPPQPRKNTKKTQNVEPENDNSPMEIENAVGKKPPQPRKNT 1227

Query: 2546 CKGKSVEPQVDDNS 2587
             K ++VEP+ D++S
Sbjct: 1228 KKTQNVEPENDNSS 1241



 Score =  348 bits (893), Expect = 2e-96
 Identities = 186/278 (66%), Positives = 216/278 (77%), Gaps = 19/278 (6%)
 Frame = +2

Query: 59  MEKPPLRTSNAANIPSETF--IFREMTQREHILRHPNIYVGSMEKHTQDLWVFKKDEIVY 232
           MEK PL+TSNAANIPS+T   ++++ TQ EHIL  P+ YVGS+EKHTQ+LWV++ DE+V 
Sbjct: 1   MEKRPLQTSNAANIPSKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDEMVN 60

Query: 233 RSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEVDQE 412
           RSISYVPGLYKIFD ILV+A DNK RDPSMDSLKVTIDP  NTVSVY+N +GVP E+ QE
Sbjct: 61  RSISYVPGLYKIFDEILVNAADNKQRDPSMDSLKVTIDPEANTVSVYNNGDGVPVEIHQE 120

Query: 413 EKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLKKYK 541
           EK YVPELI                   GRNGY GAKLT IFSTE IIETADG  LKKYK
Sbjct: 121 EKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGY-GAKLTNIFSTEFIIETADGRRLKKYK 179

Query: 542 QAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAWCL 721
           Q F++NM  +S+P IT CK +ENWTKVTFKPDLEKF+MT+LEEDVVALM+KRVLDMA CL
Sbjct: 180 QVFSDNMGKKSEPVITKCKASENWTKVTFKPDLEKFKMTYLEEDVVALMKKRVLDMAGCL 239

Query: 722 GKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
           GK+VKVEL+G L+      SF  Y DL +KSAEKS+P+
Sbjct: 240 GKTVKVELNGTLIR---FKSFRDYADLFLKSAEKSKPM 274



 Score = 48.5 bits (114), Expect(2) = 9e-09
 Identities = 25/34 (73%), Positives = 28/34 (82%)
 Frame = +2

Query: 3146 RNVGTKRTLGEKLLTDMLQPAEGTGTSPEKKVRK 3247
            RNVGTK+  G+K+LTDMLQPAE    SPEKKVRK
Sbjct: 1371 RNVGTKQLSGQKILTDMLQPAE----SPEKKVRK 1400



 Score = 43.1 bits (100), Expect(2) = 9e-09
 Identities = 21/26 (80%), Positives = 22/26 (84%)
 Frame = +3

Query: 3234 RK*GKMMESPFNKKSGSILGRAANKD 3311
            +K  KM ESPFNKKSGSILGR ANKD
Sbjct: 1396 KKVRKMRESPFNKKSGSILGRDANKD 1421



 Score = 72.0 bits (175), Expect = 9e-09
 Identities = 43/83 (51%), Positives = 50/83 (60%), Gaps = 20/83 (24%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQEDG----------------YEYLLSVPIRTLTFEGFLKLL 2668
            KGKS EPQV    DDNSE +EDG                YEYLLS+ I TLT E   KLL
Sbjct: 1064 KGKSSEPQVAGANDDNSEEREDGEQETGTVRVEEATWGDYEYLLSLSIGTLTLESVQKLL 1123

Query: 2669 ADKARMEKEFDILKATPTESLWM 2737
             +KA  EKEF+IL  TP++SLW+
Sbjct: 1124 DEKAEKEKEFEILMGTPSKSLWL 1146


>gb|PNY06816.1| DNA topoisomerase 2-like protein [Trifolium pratense]
          Length = 1254

 Score =  625 bits (1612), Expect = 0.0
 Identities = 348/613 (56%), Positives = 398/613 (64%), Gaps = 27/613 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            NAIEL  AFS+KKAEDRKT I +FEPGT RD    L NYKN  NKELILFSRAD+QRSIP
Sbjct: 450  NAIEL--AFSKKKAEDRKTWIRNFEPGTCRDHEAKLINYKNFVNKELILFSRADLQRSIP 507

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++GMAQDFV
Sbjct: 508  SMVDGLKPGQRKILFCSFKKKLVKEIKVGQFIGYVSEHSAYHHGEQSLASTIIGMAQDFV 567

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  SR IYTELN VTRCLFHE+DDKL+   +E+GRSI
Sbjct: 568  GSNNINLLKPNGQFGTRNLGGKDHASSRYIYTELNTVTRCLFHEDDDKLLEYLNEEGRSI 627

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EPNWYIPIIPLVLVNG+E    GW SYIP+YNPREIIAN++ LL  E  V MDPWYRGF 
Sbjct: 628  EPNWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPREIIANVRRLLNEEEMVPMDPWYRGFR 687

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            GTIEKS KEG Y V+G+  EID +TF ITELP+R WTQDYK+FLESIT+G PNVKDPLIE
Sbjct: 688  GTIEKSAKEGGYIVSGSVVEIDEQTFRITELPVRKWTQDYKQFLESITDGTPNVKDPLIE 747

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI+++MK +K   I QEGL KKFKLT TISTSNMHLFDA+GKIKKFD P
Sbjct: 748  DFRQNGDDAIVDIEVKMKPEKIASIMQEGLFKKFKLTNTISTSNMHLFDAEGKIKKFDTP 807

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEF+PLR+EYYE+RK YI           DNK RFI GV+ GEIIV          
Sbjct: 808  EQILEEFYPLRMEYYERRKKYILANLERLLLILDNKVRFILGVVNGEIIVSNRKKAELLI 867

Query: 2096 XXXXXGFTPMPR------KVAGENDDNSEAEED-----------------GYEYLLSLPI 2206
                 GFTPM +      +VAG NDDNSE +ED                  YEYLLSL I
Sbjct: 868  ELKQKGFTPMRKGKSAEPQVAGANDDNSEGQEDEQETVSRPVSVEGATWGDYEYLLSLSI 927

Query: 2207 RTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2386
             TLT                 ++ L     +S                            
Sbjct: 928  GTLTLESVQKLLDEKAEKEKEYEILMGTPTKSLWLKDLDDFEKKLDELDSKEAEDDRKRS 987

Query: 2387 XLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSMEV-GILKATPTNTLCKG 2554
              +   K TANG A K A+KPPQP KNTKK K+ EP+   +SMEV   ++          
Sbjct: 988  --SQASKKTANGFAAKPAKKPPQPRKNTKKNKDVEPENDNSSMEVENAVEVVKPKGRVGS 1045

Query: 2555 KSVEPQVDDNSEV 2593
            K+ + +  D S++
Sbjct: 1046 KNTQKKAGDESDI 1058



 Score =  123 bits (309), Expect = 1e-24
 Identities = 62/91 (68%), Positives = 72/91 (79%)
 Frame = +2

Query: 560 MEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAWCLGKSVKV 739
           M  +S+P IT CK NENWTKVTFKPDLEKF+MT+LEEDVVALM+KRVLDMA C GK+VKV
Sbjct: 1   MGTKSEPVITKCKANENWTKVTFKPDLEKFKMTYLEEDVVALMKKRVLDMAGCFGKTVKV 60

Query: 740 ELDGKLVGTGIINSFEHYVDLHMKSAEKSRP 832
           EL+G L+      SF  Y DL +K AEKS+P
Sbjct: 61  ELNGTLIR---FKSFRDYADLFLKCAEKSKP 88



 Score = 76.6 bits (187), Expect = 3e-10
 Identities = 56/136 (41%), Positives = 63/136 (46%), Gaps = 21/136 (15%)
 Frame = +2

Query: 2519 LKATPTNTLCKGKSVEPQV----DDNSEVQED-----------------GYEYLLSVPIR 2635
            LK      + KGKS EPQV    DDNSE QED                  YEYLLS+ I 
Sbjct: 869  LKQKGFTPMRKGKSAEPQVAGANDDNSEGQEDEQETVSRPVSVEGATWGDYEYLLSLSIG 928

Query: 2636 TLTFEGFLKLLADKARMEKEFDILKATPTESLWMAXXXXXXXXXXXXXXXXXXXXXXXXX 2815
            TLT E   KLL +KA  EKE++IL  TPT+SLW+                          
Sbjct: 929  TLTLESVQKLLDEKAEKEKEYEILMGTPTKSLWL-KDLDDFEKKLDELDSKEAEDDRKRS 987

Query: 2816 XQAGKKTANDFATKAA 2863
             QA KKTAN FA K A
Sbjct: 988  SQASKKTANGFAAKPA 1003


>dbj|GAU12625.1| hypothetical protein TSUD_121160 [Trifolium subterraneum]
          Length = 1315

 Score =  626 bits (1615), Expect = 0.0
 Identities = 354/611 (57%), Positives = 394/611 (64%), Gaps = 32/611 (5%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            +AIEL  AFS+KKAEDRKT I +FEPGT RD    L NYK+  NKELILFSRAD+QRSIP
Sbjct: 449  HAIEL--AFSKKKAEDRKTWIRNFEPGTCRDHDAKLINYKDFVNKELILFSRADLQRSIP 506

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++GMAQDFV
Sbjct: 507  SMVDGLKPGQRKILFCSFKKKLVKEIKVGQFIGYVSEHSAYHHGEQSLASTIIGMAQDFV 566

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  SR IYTELN VTRCLFHENDDKL+   +E+GRSI
Sbjct: 567  GSNNINLLKPNGQFGTRNLGGKDHASSRYIYTELNTVTRCLFHENDDKLLEYLNEEGRSI 626

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EP WYIPIIPLVLVNG+E    GW SYIP+YNPREI AN++ LL  E  V MDPWYRGF 
Sbjct: 627  EPTWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPREICANVRRLLNDEEMVPMDPWYRGFR 686

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            GTIEKS KEG Y VNG+  EID +TF ITELPIR WTQDYK+FLESIT+G PNVKDPLIE
Sbjct: 687  GTIEKSAKEGGYIVNGSVVEIDEQTFRITELPIRKWTQDYKQFLESITDGTPNVKDPLIE 746

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+   VDI+++MK DK D I QEGL KKFKLT TISTSNMHLFDA+GKIKKFDNP
Sbjct: 747  DFRQNGDDEIVDIEVKMKADKIDTIMQEGLFKKFKLTGTISTSNMHLFDAEGKIKKFDNP 806

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEF+PLRLEYYEKRK YI           DNK RFI GV+ GEIIV          
Sbjct: 807  EQILEEFYPLRLEYYEKRKKYILANLERLLLILDNKVRFILGVVNGEIIVSNRKKAELLK 866

Query: 2096 XXXXXGFTPMPRK-------VAGENDDNSEAEED------------------GYEYLLSL 2200
                 GFTPMPRK       VAG ND++SE  ED                   YEYLLSL
Sbjct: 867  ELKQKGFTPMPRKGKSSEPQVAGANDESSEEREDIEQETGSQPVRVEEATWGDYEYLLSL 926

Query: 2201 PIRTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXX 2380
             I TLT                 F+ L   TP                            
Sbjct: 927  SIGTLTLESVQKLLNEKAEKEKEFEIL-MGTPSKALWLKDLDEFEKKLDELDSKEAEEGR 985

Query: 2381 XXXLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSME----VGILKATPTN 2539
                  + K   NG A+K A+KPPQP KNTKK +N EP+   + ME    VG     P  
Sbjct: 986  KRSSQASKK---NGFASKPAKKPPQPRKNTKKAQNIEPENDNSPMEIENAVGKKAPQPRK 1042

Query: 2540 TLCKGKSVEPQ 2572
               K ++VEP+
Sbjct: 1043 NTKKTQNVEPE 1053



 Score =  119 bits (298), Expect = 3e-23
 Identities = 72/135 (53%), Positives = 89/135 (65%), Gaps = 12/135 (8%)
 Frame = +2

Query: 560 MEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAWCLGKSVKV 739
           M  +++P IT CK +ENWTKVTFKPDLEKF+MT+LEEDVVALM+KRVLDMA CLGK+VKV
Sbjct: 1   MGKKAEPVITKCKASENWTKVTFKPDLEKFKMTYLEEDVVALMKKRVLDMAGCLGKTVKV 60

Query: 740 ELDGKLVGTGIINSFEHYVDLHMKSAE--KSRPVNAI--------ELLVAFSEKKAEDRK 889
           EL+G L+      SF  Y DL +KSAE  KS P+  I        E+ V+ SE + +   
Sbjct: 61  ELNGTLIR---FKSFRDYADLFLKSAEKYKSTPLPRIHAKVGDRWEICVSLSEGQFQQVS 117

Query: 890 --TSIPDFEPGTFRD 928
              SI   + GT  D
Sbjct: 118 FVNSIATIKGGTHVD 132



 Score = 63.9 bits (154), Expect = 3e-06
 Identities = 39/85 (45%), Positives = 49/85 (57%), Gaps = 22/85 (25%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQED------------------GYEYLLSVPIRTLTFEGFLK 2662
            KGKS EPQV    D++SE +ED                   YEYLLS+ I TLT E   K
Sbjct: 879  KGKSSEPQVAGANDESSEEREDIEQETGSQPVRVEEATWGDYEYLLSLSIGTLTLESVQK 938

Query: 2663 LLADKARMEKEFDILKATPTESLWM 2737
            LL +KA  EKEF+IL  TP+++LW+
Sbjct: 939  LLNEKAEKEKEFEILMGTPSKALWL 963


>ref|XP_015936924.1| DNA topoisomerase 2 isoform X2 [Arachis duranensis]
          Length = 1490

 Score =  619 bits (1597), Expect = 0.0
 Identities = 337/599 (56%), Positives = 387/599 (64%), Gaps = 26/599 (4%)
 Frame = +2

Query: 794  VDLHMKSAEKSRPVNAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKE 973
            +D H K        + I + +AFS+KK EDRKT I +FEPGT RD      NY++  NKE
Sbjct: 631  LDKHRKDFVWDDDQDGIAIELAFSKKKTEDRKTWIRNFEPGTCRDHMMKRINYRDFVNKE 690

Query: 974  LILFSRADIQRSIPSMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREP 1153
            LILFSRAD+QRSIPSMVDGLKP QRKI            I VGQFI YV EH  Y H E 
Sbjct: 691  LILFSRADLQRSIPSMVDGLKPGQRKILFCSFKKKLFKEIKVGQFIGYVSEHSAYHHGEQ 750

Query: 1154 SLASTVVGMAQDFVGSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHEND 1333
            SLAST++GMAQDFVGSNNINLLKPNGQFGTRN+GGKDH  +R IYTELNP+TRCLFHE+D
Sbjct: 751  SLASTIIGMAQDFVGSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNPITRCLFHEDD 810

Query: 1334 DKLVSCEDEDGRSIEPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKG 1513
            DKL+   +EDGRSIEP+WYIPIIPLVLVNG+E    GW SYIP+YNPREIIAN++ +L G
Sbjct: 811  DKLLEYLNEDGRSIEPSWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPREIIANVRRMLSG 870

Query: 1514 ENTVKMDPWYRGFTGTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLES 1693
            E  + MDPWYRGF G IEKS KEG Y VNG   EID + F ITELPIR WTQDYK+FLES
Sbjct: 871  EAMLPMDPWYRGFHGVIEKSAKEGGYIVNGMIEEIDEQVFRITELPIRRWTQDYKQFLES 930

Query: 1694 ITEGAPNVKDPLIEEFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMH 1873
            +T+G+PNVKDPLIE+FR+ G+ A VDI++R+KLDK  +I QEGL KKFKLT+TISTSNMH
Sbjct: 931  VTDGSPNVKDPLIEDFRQNGDDAIVDIEVRLKLDKIAMIMQEGLLKKFKLTSTISTSNMH 990

Query: 1874 LFDAKGKIKKFDNPEQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKG 2053
            LFDA+GKIKK+D PEQ+LEEFFPLRLEYY KRK +I           DNK RFI GV+ G
Sbjct: 991  LFDAEGKIKKYDTPEQVLEEFFPLRLEYYGKRKQHILNNLERLLLILDNKVRFILGVVNG 1050

Query: 2054 EIIVRYSXXXXXXXXXXXXGFTPMPRK-------VAGENDDNSEAEED------------ 2176
            EIIV               GFTPMPRK       VAG NDD SE ++D            
Sbjct: 1051 EIIVSNRKKADLLMELQQKGFTPMPRKGKSAEPQVAGANDDISEEQDDDTTREETATVEG 1110

Query: 2177 ----GYEYLLSLPIRTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXX 2344
                 YEYLLSLPI +LT                 F+ LK   P S              
Sbjct: 1111 AKRGDYEYLLSLPIGSLTIESVQKLLAEKDEKEKEFEILKATPPTSMWMKDLDELEKKLD 1170

Query: 2345 XXXXXXXXXXXXXXXLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSMEV 2512
                                       A  AA+KPPQP KNTKK KN EP+   +SME+
Sbjct: 1171 EMDSKAAEEQQKRSSQGNRKTSNRGISAAAAAKKPPQPRKNTKKAKNVEPENDNSSMEI 1229



 Score =  317 bits (811), Expect = 1e-85
 Identities = 170/285 (59%), Positives = 203/285 (71%), Gaps = 28/285 (9%)
 Frame = +2

Query: 62  EKPPLRTSNAANIPSETF---------IFREMTQREHILRHPNIYVGSMEKHTQDLWVFK 214
           +K PL TS A NIP+ T          ++++ TQ EHIL  P+ YVGS+EKHTQ LWV+ 
Sbjct: 5   KKRPLHTSTAVNIPTSTAPAPGKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQTLWVYN 64

Query: 215 --KDEIVYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNG 388
              +E+VYR ++YVPGLYKIFD ILV+A DNK RDPSMDSLKV IDP    +SV++N +G
Sbjct: 65  DINNEMVYRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSLKVVIDPERGLISVFNNGDG 124

Query: 389 VPEEVDQEEKAYVPELILD-----------------GRNGYGGAKLTIIFSTECIIETAD 517
           VP E+ QEEK YVPELI                   GRNGYG AKLT IFSTE +IETAD
Sbjct: 125 VPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYG-AKLTNIFSTEFVIETAD 183

Query: 518 GCHLKKYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKR 697
           G   KKYKQ F++NM  +SDP IT CKE ENWTKVTFKPDLEKF+M  LEEDVV LM+KR
Sbjct: 184 GKRQKKYKQVFSDNMGKKSDPVITKCKEGENWTKVTFKPDLEKFKMAELEEDVVVLMKKR 243

Query: 698 VLDMAWCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRP 832
           V+DMA CLGK+VKVEL+GK +    + SF  Y DL++KSAEKS+P
Sbjct: 244 VVDMAGCLGKTVKVELNGKAIK---LKSFRDYADLYLKSAEKSKP 285



 Score = 71.2 bits (173), Expect = 2e-08
 Identities = 43/83 (51%), Positives = 49/83 (59%), Gaps = 20/83 (24%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQEDG----------------YEYLLSVPIRTLTFEGFLKLL 2668
            KGKS EPQV    DD SE Q+D                 YEYLLS+PI +LT E   KLL
Sbjct: 1077 KGKSAEPQVAGANDDISEEQDDDTTREETATVEGAKRGDYEYLLSLPIGSLTIESVQKLL 1136

Query: 2669 ADKARMEKEFDILKATPTESLWM 2737
            A+K   EKEF+ILKATP  S+WM
Sbjct: 1137 AEKDEKEKEFEILKATPPTSMWM 1159


>ref|XP_015936922.1| DNA topoisomerase 2 isoform X1 [Arachis duranensis]
          Length = 1521

 Score =  619 bits (1597), Expect = 0.0
 Identities = 337/599 (56%), Positives = 387/599 (64%), Gaps = 26/599 (4%)
 Frame = +2

Query: 794  VDLHMKSAEKSRPVNAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKE 973
            +D H K        + I + +AFS+KK EDRKT I +FEPGT RD      NY++  NKE
Sbjct: 662  LDKHRKDFVWDDDQDGIAIELAFSKKKTEDRKTWIRNFEPGTCRDHMMKRINYRDFVNKE 721

Query: 974  LILFSRADIQRSIPSMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREP 1153
            LILFSRAD+QRSIPSMVDGLKP QRKI            I VGQFI YV EH  Y H E 
Sbjct: 722  LILFSRADLQRSIPSMVDGLKPGQRKILFCSFKKKLFKEIKVGQFIGYVSEHSAYHHGEQ 781

Query: 1154 SLASTVVGMAQDFVGSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHEND 1333
            SLAST++GMAQDFVGSNNINLLKPNGQFGTRN+GGKDH  +R IYTELNP+TRCLFHE+D
Sbjct: 782  SLASTIIGMAQDFVGSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNPITRCLFHEDD 841

Query: 1334 DKLVSCEDEDGRSIEPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKG 1513
            DKL+   +EDGRSIEP+WYIPIIPLVLVNG+E    GW SYIP+YNPREIIAN++ +L G
Sbjct: 842  DKLLEYLNEDGRSIEPSWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPREIIANVRRMLSG 901

Query: 1514 ENTVKMDPWYRGFTGTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLES 1693
            E  + MDPWYRGF G IEKS KEG Y VNG   EID + F ITELPIR WTQDYK+FLES
Sbjct: 902  EAMLPMDPWYRGFHGVIEKSAKEGGYIVNGMIEEIDEQVFRITELPIRRWTQDYKQFLES 961

Query: 1694 ITEGAPNVKDPLIEEFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMH 1873
            +T+G+PNVKDPLIE+FR+ G+ A VDI++R+KLDK  +I QEGL KKFKLT+TISTSNMH
Sbjct: 962  VTDGSPNVKDPLIEDFRQNGDDAIVDIEVRLKLDKIAMIMQEGLLKKFKLTSTISTSNMH 1021

Query: 1874 LFDAKGKIKKFDNPEQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKG 2053
            LFDA+GKIKK+D PEQ+LEEFFPLRLEYY KRK +I           DNK RFI GV+ G
Sbjct: 1022 LFDAEGKIKKYDTPEQVLEEFFPLRLEYYGKRKQHILNNLERLLLILDNKVRFILGVVNG 1081

Query: 2054 EIIVRYSXXXXXXXXXXXXGFTPMPRK-------VAGENDDNSEAEED------------ 2176
            EIIV               GFTPMPRK       VAG NDD SE ++D            
Sbjct: 1082 EIIVSNRKKADLLMELQQKGFTPMPRKGKSAEPQVAGANDDISEEQDDDTTREETATVEG 1141

Query: 2177 ----GYEYLLSLPIRTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXX 2344
                 YEYLLSLPI +LT                 F+ LK   P S              
Sbjct: 1142 AKRGDYEYLLSLPIGSLTIESVQKLLAEKDEKEKEFEILKATPPTSMWMKDLDELEKKLD 1201

Query: 2345 XXXXXXXXXXXXXXXLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSMEV 2512
                                       A  AA+KPPQP KNTKK KN EP+   +SME+
Sbjct: 1202 EMDSKAAEEQQKRSSQGNRKTSNRGISAAAAAKKPPQPRKNTKKAKNVEPENDNSSMEI 1260



 Score =  317 bits (811), Expect = 1e-85
 Identities = 170/285 (59%), Positives = 203/285 (71%), Gaps = 28/285 (9%)
 Frame = +2

Query: 62  EKPPLRTSNAANIPSETF---------IFREMTQREHILRHPNIYVGSMEKHTQDLWVFK 214
           +K PL TS A NIP+ T          ++++ TQ EHIL  P+ YVGS+EKHTQ LWV+ 
Sbjct: 5   KKRPLHTSTAVNIPTSTAPAPGKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQTLWVYN 64

Query: 215 --KDEIVYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNG 388
              +E+VYR ++YVPGLYKIFD ILV+A DNK RDPSMDSLKV IDP    +SV++N +G
Sbjct: 65  DINNEMVYRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSLKVVIDPERGLISVFNNGDG 124

Query: 389 VPEEVDQEEKAYVPELILD-----------------GRNGYGGAKLTIIFSTECIIETAD 517
           VP E+ QEEK YVPELI                   GRNGYG AKLT IFSTE +IETAD
Sbjct: 125 VPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYG-AKLTNIFSTEFVIETAD 183

Query: 518 GCHLKKYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKR 697
           G   KKYKQ F++NM  +SDP IT CKE ENWTKVTFKPDLEKF+M  LEEDVV LM+KR
Sbjct: 184 GKRQKKYKQVFSDNMGKKSDPVITKCKEGENWTKVTFKPDLEKFKMAELEEDVVVLMKKR 243

Query: 698 VLDMAWCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRP 832
           V+DMA CLGK+VKVEL+GK +    + SF  Y DL++KSAEKS+P
Sbjct: 244 VVDMAGCLGKTVKVELNGKAIK---LKSFRDYADLYLKSAEKSKP 285



 Score = 71.2 bits (173), Expect = 2e-08
 Identities = 43/83 (51%), Positives = 49/83 (59%), Gaps = 20/83 (24%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQEDG----------------YEYLLSVPIRTLTFEGFLKLL 2668
            KGKS EPQV    DD SE Q+D                 YEYLLS+PI +LT E   KLL
Sbjct: 1108 KGKSAEPQVAGANDDISEEQDDDTTREETATVEGAKRGDYEYLLSLPIGSLTIESVQKLL 1167

Query: 2669 ADKARMEKEFDILKATPTESLWM 2737
            A+K   EKEF+ILKATP  S+WM
Sbjct: 1168 AEKDEKEKEFEILKATPPTSMWM 1190


>ref|XP_016170361.1| DNA topoisomerase 2 isoform X2 [Arachis ipaensis]
          Length = 1486

 Score =  617 bits (1590), Expect = 0.0
 Identities = 336/585 (57%), Positives = 384/585 (65%), Gaps = 26/585 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            +AIEL  AFS+KK EDRKT I +FEPGT RD      NY++  NKELILFSRAD+QRSIP
Sbjct: 647  SAIEL--AFSKKKTEDRKTWIRNFEPGTCRDHMMKHINYRDFVNKELILFSRADLQRSIP 704

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++GMAQDFV
Sbjct: 705  SMVDGLKPGQRKILFCSFKKKLFKEIKVGQFIGYVSEHSAYHHGEQSLASTIIGMAQDFV 764

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  +R IYTELNP+TRCLFHE+DDKL+   +EDGRSI
Sbjct: 765  GSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNPITRCLFHEDDDKLLEYLNEDGRSI 824

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EP+WYIPIIPLVLVNG+E    GW SYIP+YNPRE+IAN++ +L GE  + MDPWYRGF 
Sbjct: 825  EPSWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPREVIANVRRMLSGEAMLPMDPWYRGFH 884

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            G IEKS KEG Y VNG T EID + F ITELPIR WTQDYK+FLES+T+G+PNVKDPLIE
Sbjct: 885  GVIEKSAKEGGYIVNGMTEEIDEQVFRITELPIRRWTQDYKQFLESVTDGSPNVKDPLIE 944

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI++R+KLDK  +I QEGL KKFKLT+TISTSNMHLFDA+GKIKK+D P
Sbjct: 945  DFRQNGDDAIVDIEVRLKLDKIAMIMQEGLLKKFKLTSTISTSNMHLFDAEGKIKKYDTP 1004

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQ+LEEFFPLRLEYY +RK +I           DNK RFI GV+ GEIIV          
Sbjct: 1005 EQVLEEFFPLRLEYYGRRKQHILNNLERLLLILDNKVRFILGVVNGEIIVSNRKKADLLM 1064

Query: 2096 XXXXXGFTPMPRK-------VAGENDDNSEAEED----------------GYEYLLSLPI 2206
                 GFTPMPRK       VAG NDD SE ++D                 YEYLLSLPI
Sbjct: 1065 ELQQKGFTPMPRKGKSAEPQVAGANDDISEEQDDDTTREETATVEGAKRGDYEYLLSLPI 1124

Query: 2207 RTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2386
             TLT                 F+ LK   P S                            
Sbjct: 1125 GTLTIESVQKLLAEKDEKEKEFEILKATPPTSMWMKDLDELEKKLDEMDSKAAEEQQKRS 1184

Query: 2387 XLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSMEV 2512
                         A  AA+KPPQP KNTKK   AEP+   +SME+
Sbjct: 1185 SQGNRKTSNRGISAAAAAKKPPQPRKNTKKATKAEPENDNSSMEI 1229



 Score =  317 bits (811), Expect = 9e-86
 Identities = 170/285 (59%), Positives = 203/285 (71%), Gaps = 28/285 (9%)
 Frame = +2

Query: 62  EKPPLRTSNAANIPSETF---------IFREMTQREHILRHPNIYVGSMEKHTQDLWVFK 214
           +K PL TS A NIP+ T          ++++ TQ EHIL  P+ YVGS+EKHTQ LWV+ 
Sbjct: 5   KKRPLHTSTAVNIPASTAPASGKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQTLWVYN 64

Query: 215 --KDEIVYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNG 388
              +E+VYR ++YVPGLYKIFD ILV+A DNK RDPSMDSLKV IDP    +SV++N +G
Sbjct: 65  DINNEMVYRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSLKVVIDPERGLISVFNNGDG 124

Query: 389 VPEEVDQEEKAYVPELILD-----------------GRNGYGGAKLTIIFSTECIIETAD 517
           VP E+ QEEK YVPELI                   GRNGYG AKLT IFSTE +IETAD
Sbjct: 125 VPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYG-AKLTNIFSTEFVIETAD 183

Query: 518 GCHLKKYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKR 697
           G   KKYKQ F++NM  +SDP IT CKE ENWTKVTFKPDLEKF+M  LEEDVV LM+KR
Sbjct: 184 GKRQKKYKQVFSDNMGKKSDPVITKCKEGENWTKVTFKPDLEKFKMAELEEDVVVLMKKR 243

Query: 698 VLDMAWCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRP 832
           V+DMA CLGK+VKVEL+GK +    + SF  Y DL++KSAEKS+P
Sbjct: 244 VVDMAGCLGKTVKVELNGKAIK---LKSFRDYADLYLKSAEKSKP 285



 Score = 72.8 bits (177), Expect = 5e-09
 Identities = 44/83 (53%), Positives = 49/83 (59%), Gaps = 20/83 (24%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQEDG----------------YEYLLSVPIRTLTFEGFLKLL 2668
            KGKS EPQV    DD SE Q+D                 YEYLLS+PI TLT E   KLL
Sbjct: 1077 KGKSAEPQVAGANDDISEEQDDDTTREETATVEGAKRGDYEYLLSLPIGTLTIESVQKLL 1136

Query: 2669 ADKARMEKEFDILKATPTESLWM 2737
            A+K   EKEF+ILKATP  S+WM
Sbjct: 1137 AEKDEKEKEFEILKATPPTSMWM 1159


>ref|XP_016170360.1| DNA topoisomerase 2 isoform X1 [Arachis ipaensis]
          Length = 1517

 Score =  617 bits (1590), Expect = 0.0
 Identities = 336/585 (57%), Positives = 384/585 (65%), Gaps = 26/585 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            +AIEL  AFS+KK EDRKT I +FEPGT RD      NY++  NKELILFSRAD+QRSIP
Sbjct: 678  SAIEL--AFSKKKTEDRKTWIRNFEPGTCRDHMMKHINYRDFVNKELILFSRADLQRSIP 735

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++GMAQDFV
Sbjct: 736  SMVDGLKPGQRKILFCSFKKKLFKEIKVGQFIGYVSEHSAYHHGEQSLASTIIGMAQDFV 795

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  +R IYTELNP+TRCLFHE+DDKL+   +EDGRSI
Sbjct: 796  GSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNPITRCLFHEDDDKLLEYLNEDGRSI 855

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EP+WYIPIIPLVLVNG+E    GW SYIP+YNPRE+IAN++ +L GE  + MDPWYRGF 
Sbjct: 856  EPSWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPREVIANVRRMLSGEAMLPMDPWYRGFH 915

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            G IEKS KEG Y VNG T EID + F ITELPIR WTQDYK+FLES+T+G+PNVKDPLIE
Sbjct: 916  GVIEKSAKEGGYIVNGMTEEIDEQVFRITELPIRRWTQDYKQFLESVTDGSPNVKDPLIE 975

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI++R+KLDK  +I QEGL KKFKLT+TISTSNMHLFDA+GKIKK+D P
Sbjct: 976  DFRQNGDDAIVDIEVRLKLDKIAMIMQEGLLKKFKLTSTISTSNMHLFDAEGKIKKYDTP 1035

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQ+LEEFFPLRLEYY +RK +I           DNK RFI GV+ GEIIV          
Sbjct: 1036 EQVLEEFFPLRLEYYGRRKQHILNNLERLLLILDNKVRFILGVVNGEIIVSNRKKADLLM 1095

Query: 2096 XXXXXGFTPMPRK-------VAGENDDNSEAEED----------------GYEYLLSLPI 2206
                 GFTPMPRK       VAG NDD SE ++D                 YEYLLSLPI
Sbjct: 1096 ELQQKGFTPMPRKGKSAEPQVAGANDDISEEQDDDTTREETATVEGAKRGDYEYLLSLPI 1155

Query: 2207 RTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2386
             TLT                 F+ LK   P S                            
Sbjct: 1156 GTLTIESVQKLLAEKDEKEKEFEILKATPPTSMWMKDLDELEKKLDEMDSKAAEEQQKRS 1215

Query: 2387 XLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSMEV 2512
                         A  AA+KPPQP KNTKK   AEP+   +SME+
Sbjct: 1216 SQGNRKTSNRGISAAAAAKKPPQPRKNTKKATKAEPENDNSSMEI 1260



 Score =  317 bits (811), Expect = 1e-85
 Identities = 170/285 (59%), Positives = 203/285 (71%), Gaps = 28/285 (9%)
 Frame = +2

Query: 62  EKPPLRTSNAANIPSETF---------IFREMTQREHILRHPNIYVGSMEKHTQDLWVFK 214
           +K PL TS A NIP+ T          ++++ TQ EHIL  P+ YVGS+EKHTQ LWV+ 
Sbjct: 5   KKRPLHTSTAVNIPASTAPASGKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQTLWVYN 64

Query: 215 --KDEIVYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNG 388
              +E+VYR ++YVPGLYKIFD ILV+A DNK RDPSMDSLKV IDP    +SV++N +G
Sbjct: 65  DINNEMVYRPVTYVPGLYKIFDEILVNAADNKQRDPSMDSLKVVIDPERGLISVFNNGDG 124

Query: 389 VPEEVDQEEKAYVPELILD-----------------GRNGYGGAKLTIIFSTECIIETAD 517
           VP E+ QEEK YVPELI                   GRNGYG AKLT IFSTE +IETAD
Sbjct: 125 VPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYG-AKLTNIFSTEFVIETAD 183

Query: 518 GCHLKKYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKR 697
           G   KKYKQ F++NM  +SDP IT CKE ENWTKVTFKPDLEKF+M  LEEDVV LM+KR
Sbjct: 184 GKRQKKYKQVFSDNMGKKSDPVITKCKEGENWTKVTFKPDLEKFKMAELEEDVVVLMKKR 243

Query: 698 VLDMAWCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRP 832
           V+DMA CLGK+VKVEL+GK +    + SF  Y DL++KSAEKS+P
Sbjct: 244 VVDMAGCLGKTVKVELNGKAIK---LKSFRDYADLYLKSAEKSKP 285



 Score = 72.8 bits (177), Expect = 5e-09
 Identities = 44/83 (53%), Positives = 49/83 (59%), Gaps = 20/83 (24%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQEDG----------------YEYLLSVPIRTLTFEGFLKLL 2668
            KGKS EPQV    DD SE Q+D                 YEYLLS+PI TLT E   KLL
Sbjct: 1108 KGKSAEPQVAGANDDISEEQDDDTTREETATVEGAKRGDYEYLLSLPIGTLTIESVQKLL 1167

Query: 2669 ADKARMEKEFDILKATPTESLWM 2737
            A+K   EKEF+ILKATP  S+WM
Sbjct: 1168 AEKDEKEKEFEILKATPPTSMWM 1190


>ref|XP_017425524.1| PREDICTED: DNA topoisomerase 2 [Vigna angularis]
 gb|KOM42453.1| hypothetical protein LR48_Vigan05g005700 [Vigna angularis]
 dbj|BAT93356.1| hypothetical protein VIGAN_07230300 [Vigna angularis var. angularis]
          Length = 1480

 Score =  609 bits (1570), Expect = 0.0
 Identities = 332/586 (56%), Positives = 391/586 (66%), Gaps = 27/586 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            +AIE+  AFS+KKAEDRKT I +FEPGTFRD +    NY++  NKELILFSRAD+QRSIP
Sbjct: 640  SAIEM--AFSKKKAEDRKTWIRNFEPGTFRDHSARYINYRDFVNKELILFSRADLQRSIP 697

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I V QFI YV EH  Y H E SL+ST++ MAQDFV
Sbjct: 698  SMVDGLKPGQRKILFCSFKKKLFKEIKVAQFIGYVSEHSAYHHGEQSLSSTIINMAQDFV 757

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  +R IYTELN +TRC+FHE+DDKL+    EDG+SI
Sbjct: 758  GSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNNITRCIFHEDDDKLLEYLSEDGKSI 817

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EPNWY+P+IPLVLVNG+E    GW S+IP+YNPREIIAN++ LL GE  V M+PWY+GF 
Sbjct: 818  EPNWYMPVIPLVLVNGSEGIGTGWSSFIPNYNPREIIANIRRLLSGETLVPMNPWYKGFK 877

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            GTIE+S KEG Y VNG   EIDG+TF I+ELP+R WTQDYK+FLESIT+G+PNVKDPLI+
Sbjct: 878  GTIERSPKEGGYAVNGLVDEIDGQTFRISELPVRKWTQDYKQFLESITDGSPNVKDPLID 937

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI++R+KLDK   I QEGL KKFKLTT++ST+NMHLFDA+GKIKK+D+P
Sbjct: 938  DFRQNGDDAVVDIEVRIKLDKIAGIMQEGLLKKFKLTTSLSTNNMHLFDAEGKIKKYDSP 997

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            E+ILEEFFPLRL+YYE+RK +I           DNK RFI GV+ GEIIV          
Sbjct: 998  EEILEEFFPLRLDYYERRKNHILNNLERLLLVLDNKVRFILGVVSGEIIVSNRKNADLVI 1057

Query: 2096 XXXXXGFTPMPRK-------VAGEN------DDNSEAEEDG---------YEYLLSLPIR 2209
                 GFTPMPRK       VAG N      DDNS  +E G         YEYLL++ IR
Sbjct: 1058 ELQQKGFTPMPRKGKSAEPVVAGANDEEEQEDDNSTEQETGSVEAAKRGDYEYLLAMSIR 1117

Query: 2210 TLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2389
            TLT                 F+ LK  TP                               
Sbjct: 1118 TLTFESVQKLLAEKAEKEKEFEVLKA-TPSKSMWLKDLDELEKKLDEIDSKDEEEERKRS 1176

Query: 2390 LTYNYKGTANG--CATKAAEKPPQPSKNTKKTKNAEP---DTSMEV 2512
                 K +  G   ATKAA+KPPQP K TKK KN EP   D+SMEV
Sbjct: 1177 SQATRKASNRGVSAATKAAKKPPQPRKYTKKAKNVEPDNDDSSMEV 1222



 Score =  316 bits (810), Expect = 1e-85
 Identities = 168/279 (60%), Positives = 206/279 (73%), Gaps = 22/279 (7%)
 Frame = +2

Query: 65  KPPLRTSNAANIPSETF-----IFREMTQREHILRHPNIYVGSMEKHTQDLWVFKKDEIV 229
           K PL++S+AAN+ +        ++++ TQ EHIL  P+ YVGS+EKHTQ LWV++   +V
Sbjct: 6   KRPLQSSSAANVAAAAGKTIEEVYQKKTQLEHILLRPDTYVGSIEKHTQTLWVYEDGGMV 65

Query: 230 YRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEVDQ 409
            R +SYVPGLYKIFD ILV+A DNK RDPSMD+LKVTID  +NTVSV++N +GVP E+ Q
Sbjct: 66  QRPVSYVPGLYKIFDEILVNAADNKQRDPSMDALKVTIDAEQNTVSVFNNGDGVPVEIHQ 125

Query: 410 EEKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLKKY 538
           EEK YVPELI                   GRNGY GAKLT IFSTE +IETADG   KKY
Sbjct: 126 EEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGY-GAKLTNIFSTEFVIETADGKRQKKY 184

Query: 539 KQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAWC 718
           KQ F+NNM  +S+P IT CK  ENWTKVTFKPDL KF+M HLEEDVVALM+KRV+DMA C
Sbjct: 185 KQVFSNNMGKKSEPVITKCKGGENWTKVTFKPDLAKFKMDHLEEDVVALMKKRVVDMAGC 244

Query: 719 LGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
           LGK+VKVEL+G+L+    + SF  Y DL++KSAEKS+P+
Sbjct: 245 LGKTVKVELNGQLIR---MKSFRDYADLYLKSAEKSKPM 280



 Score = 76.3 bits (186), Expect = 4e-10
 Identities = 43/82 (52%), Positives = 52/82 (63%), Gaps = 19/82 (23%)
 Frame = +2

Query: 2549 KGKSVEP----------QVDDNSEVQEDG---------YEYLLSVPIRTLTFEGFLKLLA 2671
            KGKS EP          Q DDNS  QE G         YEYLL++ IRTLTFE   KLLA
Sbjct: 1070 KGKSAEPVVAGANDEEEQEDDNSTEQETGSVEAAKRGDYEYLLAMSIRTLTFESVQKLLA 1129

Query: 2672 DKARMEKEFDILKATPTESLWM 2737
            +KA  EKEF++LKATP++S+W+
Sbjct: 1130 EKAEKEKEFEVLKATPSKSMWL 1151


>gb|KHN45085.1| DNA topoisomerase 2, partial [Glycine soja]
          Length = 1379

 Score =  605 bits (1560), Expect = 0.0
 Identities = 333/611 (54%), Positives = 394/611 (64%), Gaps = 23/611 (3%)
 Frame = +2

Query: 839  AIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIPS 1018
            AIE+  AFS+KKAEDRK  I +FEPGT RD      NY++  NKELIL+SRAD+QRSIPS
Sbjct: 540  AIEM--AFSKKKAEDRKIWIRNFEPGTCRDHMAKYINYRDFVNKELILYSRADLQRSIPS 597

Query: 1019 MVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFVG 1198
            MVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++ MAQDFVG
Sbjct: 598  MVDGLKPGQRKILFCSFKKKLSKEIKVGQFIGYVSEHSAYHHGEQSLASTIINMAQDFVG 657

Query: 1199 SNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSIE 1378
            SNNINLLKPNGQFGTRN+GGKDH  +R IYTELN +TRC+FHE+DDKL+   +EDGR IE
Sbjct: 658  SNNINLLKPNGQFGTRNLGGKDHASARYIYTELNTITRCIFHEDDDKLLEYLNEDGRCIE 717

Query: 1379 PNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFTG 1558
            PNWYIP+IPLVLVNG+E    GW SYIP+YNPR+IIAN++ LL GE  V MDPWY+GF G
Sbjct: 718  PNWYIPVIPLVLVNGSEGIGTGWGSYIPNYNPRDIIANVRRLLSGETMVPMDPWYKGFKG 777

Query: 1559 TIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIEE 1738
            TIE+S KEG Y VNG+  EI+ +TF ITELP+R WTQDYK+FLESIT+G+PNVKDPLI++
Sbjct: 778  TIERSPKEGGYVVNGSVEEINEQTFRITELPVRKWTQDYKQFLESITDGSPNVKDPLIDD 837

Query: 1739 FRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNPE 1918
            FR+ G+ A VDI++RMKL+K   I QEGL KKFKLT++IST+NMHLFDA+GKIKK+DNPE
Sbjct: 838  FRQNGDDATVDIEVRMKLEKIVGIMQEGLLKKFKLTSSISTNNMHLFDAEGKIKKYDNPE 897

Query: 1919 QILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXXX 2098
            QILEEFFPLRLEYYE+RK +I           DNK RFI GV+ GEI+V           
Sbjct: 898  QILEEFFPLRLEYYERRKKHILNNLEQLLLILDNKVRFILGVVNGEIVVSNRKKAELLIE 957

Query: 2099 XXXXGFTPMPRK-------VAG-------ENDDNSEAEEDG---------YEYLLSLPIR 2209
                GFTPMPRK       VAG       E+D+N+  +E G         YEYLLS+ I 
Sbjct: 958  LQQKGFTPMPRKGKSAEPQVAGANDEEEQEDDNNTREQETGSVEGVKRGDYEYLLSMSIG 1017

Query: 2210 TLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2389
            TLT                 F+ LK  TP                               
Sbjct: 1018 TLTLEAVQKLLAEKAEKEKEFEILKA-TPSKSLWLKDLDELENKLDDIDSIEAEEERKRS 1076

Query: 2390 LTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPDTSMEVGILKATPTNTLCKGKSVEP 2569
               N K T+N   TKAA+KPPQP K TKK KN EP+       ++        KG++   
Sbjct: 1077 SQANRK-TSNRGVTKAAKKPPQPRKYTKKAKNVEPENDNSSMEIENVAEVAKPKGRAGSK 1135

Query: 2570 QVDDNSEVQED 2602
               +   V ED
Sbjct: 1136 NTQNTQPVAED 1146



 Score =  206 bits (524), Expect = 3e-50
 Identities = 112/182 (61%), Positives = 133/182 (73%), Gaps = 17/182 (9%)
 Frame = +2

Query: 341 IDPGENTVSVYHNRNGVPEEVDQEEKAYVPELILD-----------------GRNGYGGA 469
           I+   NTVSV++N +GVP E+ QEEK YVPELI                   GRNGYG A
Sbjct: 1   INAEANTVSVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYNDNEKKTTGGRNGYG-A 59

Query: 470 KLTIIFSTECIIETADGCHLKKYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKF 649
           KLT IFSTE +IETADG   KKYKQ F+NNM  +S+P IT CK  ENWTKVTFKPDLEKF
Sbjct: 60  KLTNIFSTEFVIETADGKRQKKYKQVFSNNMGKKSEPVITKCKVGENWTKVTFKPDLEKF 119

Query: 650 EMTHLEEDVVALMRKRVLDMAWCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSR 829
           +M +LEEDVVALM+KRV+DMA CLGK+VKVEL+G+++    + SF  Y DL++KSAEKSR
Sbjct: 120 KMDYLEEDVVALMKKRVVDMAGCLGKTVKVELNGQVIR---MKSFRDYADLYLKSAEKSR 176

Query: 830 PV 835
           PV
Sbjct: 177 PV 178



 Score = 73.9 bits (180), Expect = 2e-09
 Identities = 52/125 (41%), Positives = 62/125 (49%), Gaps = 20/125 (16%)
 Frame = +2

Query: 2549 KGKSVEPQV-----------DDNSEVQEDG---------YEYLLSVPIRTLTFEGFLKLL 2668
            KGKS EPQV           D+N+  QE G         YEYLLS+ I TLT E   KLL
Sbjct: 969  KGKSAEPQVAGANDEEEQEDDNNTREQETGSVEGVKRGDYEYLLSMSIGTLTLEAVQKLL 1028

Query: 2669 ADKARMEKEFDILKATPTESLWMAXXXXXXXXXXXXXXXXXXXXXXXXXXQAGKKTANDF 2848
            A+KA  EKEF+ILKATP++SLW+                           QA +KT+N  
Sbjct: 1029 AEKAEKEKEFEILKATPSKSLWL-KDLDELENKLDDIDSIEAEEERKRSSQANRKTSNRG 1087

Query: 2849 ATKAA 2863
             TKAA
Sbjct: 1088 VTKAA 1092


>ref|XP_003545986.1| PREDICTED: DNA topoisomerase 2-like [Glycine max]
 gb|KRH13973.1| hypothetical protein GLYMA_15G276000 [Glycine max]
          Length = 1484

 Score =  605 bits (1561), Expect = 0.0
 Identities = 333/611 (54%), Positives = 394/611 (64%), Gaps = 23/611 (3%)
 Frame = +2

Query: 839  AIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIPS 1018
            AIE+  AFS+KKAEDRK  I +FEPGT RD      NY++  NKELIL+SRAD+QRSIPS
Sbjct: 645  AIEM--AFSKKKAEDRKIWIRNFEPGTCRDHMAKYINYRDFVNKELILYSRADLQRSIPS 702

Query: 1019 MVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFVG 1198
            MVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++ MAQDFVG
Sbjct: 703  MVDGLKPGQRKILFCSFKKKLSKEIKVGQFIGYVSEHSAYHHGEQSLASTIINMAQDFVG 762

Query: 1199 SNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSIE 1378
            SNNINLLKPNGQFGTRN+GGKDH  +R IYTELN +TRC+FHE+DDKL+   +EDGR IE
Sbjct: 763  SNNINLLKPNGQFGTRNLGGKDHASARYIYTELNTITRCIFHEDDDKLLEYLNEDGRCIE 822

Query: 1379 PNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFTG 1558
            PNWYIP+IPLVLVNG+E    GW SYIP+YNPR+IIAN++ LL GE  V MDPWY+GF G
Sbjct: 823  PNWYIPVIPLVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLSGETMVPMDPWYKGFKG 882

Query: 1559 TIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIEE 1738
            TIE+S KEG Y VNG+  EI+ +TF ITELP+R WTQDYK+FLESIT+G+PNVKDPLI++
Sbjct: 883  TIERSPKEGGYVVNGSVEEINEQTFRITELPVRKWTQDYKQFLESITDGSPNVKDPLIDD 942

Query: 1739 FRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNPE 1918
            FR+ G+ A VDI++RMKL+K   I QEGL KKFKLT++IST+NMHLFDA+GKIKK+DNPE
Sbjct: 943  FRQNGDDATVDIEVRMKLEKIVGIMQEGLLKKFKLTSSISTNNMHLFDAEGKIKKYDNPE 1002

Query: 1919 QILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXXX 2098
            QILEEFFPLRLEYYE+RK +I           DNK RFI GV+ GEI+V           
Sbjct: 1003 QILEEFFPLRLEYYERRKKHILNNLEQLLLILDNKVRFILGVVNGEIVVSNRKKAELLIE 1062

Query: 2099 XXXXGFTPMPRK-------VAG-------ENDDNSEAEEDG---------YEYLLSLPIR 2209
                GFTPMPRK       VAG       E+D+N+  +E G         YEYLLS+ I 
Sbjct: 1063 LQQKGFTPMPRKGKSAEPQVAGANDEEEQEDDNNTREQETGSVEGVKRGDYEYLLSMSIG 1122

Query: 2210 TLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2389
            TLT                 F+ LK  TP                               
Sbjct: 1123 TLTLEAVQKLLAEKAEKEKEFEILKA-TPSKSLWLKDLDELENKLDDIDSIEAEEERKRS 1181

Query: 2390 LTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPDTSMEVGILKATPTNTLCKGKSVEP 2569
               N K T+N   TKAA+KPPQP K TKK KN EP+       ++        KG++   
Sbjct: 1182 SQANRK-TSNRGVTKAAKKPPQPRKYTKKAKNVEPENDNSSMEIENVAEVAKPKGRAGSK 1240

Query: 2570 QVDDNSEVQED 2602
               +   V ED
Sbjct: 1241 NTQNTQPVAED 1251



 Score =  319 bits (818), Expect = 1e-86
 Identities = 169/280 (60%), Positives = 209/280 (74%), Gaps = 25/280 (8%)
 Frame = +2

Query: 71  PLRTSNAANIPSETF--------IFREMTQREHILRHPNIYVGSMEKHTQDLWVFKKDEI 226
           PL++S+AAN+ +           ++++ TQ EHIL  P+ YVGS+EKHTQ LWV++ DE+
Sbjct: 8   PLQSSSAANVAAAAATGKKTIEEMYQKKTQLEHILLRPDTYVGSVEKHTQTLWVYENDEM 67

Query: 227 VYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEVD 406
           V+R++SYVPGLYKIFD ILV+A DNK RDPSMD+LKVTI+   NTVSV++N +GVP E+ 
Sbjct: 68  VHRAVSYVPGLYKIFDEILVNAADNKQRDPSMDALKVTINAEANTVSVFNNGDGVPVEIH 127

Query: 407 QEEKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLKK 535
           QEEK YVPELI                   GRNGY GAKLT IFSTE +IETADG   KK
Sbjct: 128 QEEKVYVPELIFGHLLTSSNYNDNEKKTTGGRNGY-GAKLTNIFSTEFVIETADGKRQKK 186

Query: 536 YKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAW 715
           YKQ F+NNM  +S+P IT CK  ENWTKVTFKPDLEKF+M +LEEDVVALM+KRV+DMA 
Sbjct: 187 YKQVFSNNMGKKSEPVITKCKVGENWTKVTFKPDLEKFKMDYLEEDVVALMKKRVVDMAG 246

Query: 716 CLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
           CLGK+VKVEL+G+++    + SF  Y DL++KSAEKSRPV
Sbjct: 247 CLGKTVKVELNGQVIR---MKSFRDYADLYLKSAEKSRPV 283



 Score = 73.9 bits (180), Expect = 2e-09
 Identities = 52/125 (41%), Positives = 62/125 (49%), Gaps = 20/125 (16%)
 Frame = +2

Query: 2549 KGKSVEPQV-----------DDNSEVQEDG---------YEYLLSVPIRTLTFEGFLKLL 2668
            KGKS EPQV           D+N+  QE G         YEYLLS+ I TLT E   KLL
Sbjct: 1074 KGKSAEPQVAGANDEEEQEDDNNTREQETGSVEGVKRGDYEYLLSMSIGTLTLEAVQKLL 1133

Query: 2669 ADKARMEKEFDILKATPTESLWMAXXXXXXXXXXXXXXXXXXXXXXXXXXQAGKKTANDF 2848
            A+KA  EKEF+ILKATP++SLW+                           QA +KT+N  
Sbjct: 1134 AEKAEKEKEFEILKATPSKSLWL-KDLDELENKLDDIDSIEAEEERKRSSQANRKTSNRG 1192

Query: 2849 ATKAA 2863
             TKAA
Sbjct: 1193 VTKAA 1197


>ref|XP_014501355.1| DNA topoisomerase 2 [Vigna radiata var. radiata]
          Length = 1492

 Score =  601 bits (1550), Expect = 0.0
 Identities = 331/587 (56%), Positives = 390/587 (66%), Gaps = 28/587 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            +AIE+  AFS+KKAEDRKT I +FEPGT+RD +    NY++  NKELILFSRAD+QRSIP
Sbjct: 640  SAIEM--AFSKKKAEDRKTWIRNFEPGTYRDHSARYINYRDFVNKELILFSRADLQRSIP 697

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I V QFI YV EH  Y H E SL+ST++ MAQDFV
Sbjct: 698  SMVDGLKPGQRKILFCSFKKKLFKEIKVAQFIGYVSEHSAYHHGEQSLSSTIINMAQDFV 757

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  +R IYTELN +TRC+FHE+DDKL+    EDG+SI
Sbjct: 758  GSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNNITRCIFHEDDDKLLEYLSEDGKSI 817

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EPNWY+P+IPLVLVNG+E    GW S+IP+YNPREIIAN++ LL GE  V M+PWY+GF 
Sbjct: 818  EPNWYMPVIPLVLVNGSEGIGTGWSSFIPNYNPREIIANIRRLLSGEALVPMNPWYKGFK 877

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            GTIE+S KEG Y VNG   EID +TF I+ELP+R WTQDYK+FLESIT+G+PNVKDPLI+
Sbjct: 878  GTIERSPKEGGYVVNGLAEEIDEQTFRISELPVRKWTQDYKQFLESITDGSPNVKDPLID 937

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI++RMKLDK   I QEGL KKFKLTT++ST+NMHLFDA+GKIKK+D+P
Sbjct: 938  DFRQNGDDAIVDIEVRMKLDKIAGIMQEGLLKKFKLTTSLSTNNMHLFDAEGKIKKYDSP 997

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            E+ILEEFFPLRL+YYE+RK +I           DNK RFI GV+ GEIIV          
Sbjct: 998  EEILEEFFPLRLDYYERRKNHILNNLERLLLVLDNKVRFILGVVSGEIIVNNRKNADLVI 1057

Query: 2096 XXXXXGFTPMPRK-------VAGEN------DDNSEAEEDG---------YEYLLSLPIR 2209
                 GFTPMPRK       VAG N      DDNS  +E G         YEYLL++ IR
Sbjct: 1058 ELQQKGFTPMPRKGKSAEPVVAGANDEEEQEDDNSTEQETGSVEAAKRGDYEYLLAMSIR 1117

Query: 2210 TLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2389
            TLT                 F+ LK  TP                               
Sbjct: 1118 TLTFESVQKLLAEKAEKEKEFEILKA-TPSKSMWLKDLDELEKKLDEIDSKEAEEELKRS 1176

Query: 2390 LTYNYKGTANG--CATKAAEK-PPQPSKNTKKTKNAEPD---TSMEV 2512
                 K +  G   ATKAA+K PPQP K TKK KN EPD   +SMEV
Sbjct: 1177 SQATRKASNRGVSAATKAAKKPPPQPRKYTKKAKNVEPDNDNSSMEV 1223



 Score =  321 bits (822), Expect = 4e-87
 Identities = 170/279 (60%), Positives = 207/279 (74%), Gaps = 22/279 (7%)
 Frame = +2

Query: 65  KPPLRTSNAANIPSETF-----IFREMTQREHILRHPNIYVGSMEKHTQDLWVFKKDEIV 229
           K PL++S+AAN+ +        ++++ TQ EHIL  P+ YVGS+EKHTQ LWV++  E+V
Sbjct: 6   KRPLQSSSAANVAAAAGKTIEEVYQKKTQLEHILLRPDTYVGSIEKHTQTLWVYQNGEMV 65

Query: 230 YRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEVDQ 409
            R +SYVPGLYKIFD ILV+A DNK RDPSMD+LKVTID  +NTVSVY+N +GVP E+ Q
Sbjct: 66  QRPVSYVPGLYKIFDEILVNAADNKQRDPSMDALKVTIDAEQNTVSVYNNGDGVPVEIHQ 125

Query: 410 EEKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLKKY 538
           EEK YVPELI                   GRNGY GAKLT IFSTE +IETADG   KKY
Sbjct: 126 EEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGY-GAKLTNIFSTEFVIETADGKRQKKY 184

Query: 539 KQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAWC 718
           KQ F+NNM  +S+P IT CK  ENWTKVTFKPDL KF+M HLEEDVVALM+KRV+DMA C
Sbjct: 185 KQVFSNNMGKKSEPVITKCKGGENWTKVTFKPDLAKFKMDHLEEDVVALMKKRVVDMAGC 244

Query: 719 LGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
           LGK+VKVEL+G+++    + SF  Y DL++KSAEKS+PV
Sbjct: 245 LGKTVKVELNGQVIR---MKSFRDYADLYLKSAEKSKPV 280



 Score = 76.6 bits (187), Expect = 3e-10
 Identities = 44/82 (53%), Positives = 52/82 (63%), Gaps = 19/82 (23%)
 Frame = +2

Query: 2549 KGKSVEP----------QVDDNSEVQEDG---------YEYLLSVPIRTLTFEGFLKLLA 2671
            KGKS EP          Q DDNS  QE G         YEYLL++ IRTLTFE   KLLA
Sbjct: 1070 KGKSAEPVVAGANDEEEQEDDNSTEQETGSVEAAKRGDYEYLLAMSIRTLTFESVQKLLA 1129

Query: 2672 DKARMEKEFDILKATPTESLWM 2737
            +KA  EKEF+ILKATP++S+W+
Sbjct: 1130 EKAEKEKEFEILKATPSKSMWL 1151


>ref|XP_007148908.1| hypothetical protein PHAVU_005G024200g [Phaseolus vulgaris]
 gb|ESW20902.1| hypothetical protein PHAVU_005G024200g [Phaseolus vulgaris]
          Length = 1474

 Score =  600 bits (1548), Expect = 0.0
 Identities = 327/594 (55%), Positives = 388/594 (65%), Gaps = 26/594 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            +AIE+  AFS+KKAEDRKT I +FEPGTFRD      NY++  NKELILFSRAD+QRSIP
Sbjct: 641  SAIEM--AFSKKKAEDRKTWIRNFEPGTFRDHTARYINYRDFVNKELILFSRADLQRSIP 698

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I V QFI YV EH  Y H E SL+ST++ MAQDFV
Sbjct: 699  SMVDGLKPGQRKILFCSFKKKLFKEIKVAQFIGYVSEHSAYHHGEQSLSSTIINMAQDFV 758

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNN+NLLKPNGQFGTRN+GGKDH  +R IYTELN +TRC+FHE+DDKL+    EDG+SI
Sbjct: 759  GSNNVNLLKPNGQFGTRNLGGKDHASARYIYTELNTITRCIFHEDDDKLLEYLSEDGKSI 818

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EP+WY+P+IPLVLVNG+E    GW S+IP+YNPREIIAN++ LL GE  V M+PWY+GF 
Sbjct: 819  EPSWYMPVIPLVLVNGSEGIGTGWSSFIPNYNPREIIANIRRLLSGETMVPMNPWYKGFR 878

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            G IE+S KEG Y VNG   E+D +TF I ELPIR WTQDYK+FLESIT+G+PNVKDPLI+
Sbjct: 879  GIIERSPKEGGYIVNGLVEEMDEQTFKIAELPIRKWTQDYKQFLESITDGSPNVKDPLID 938

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI++RMKLDK   I QEGL KKFKLTT++ST+NMHLFDA+G+IKK+D P
Sbjct: 939  DFRQNGDDAIVDIEVRMKLDKITGIMQEGLLKKFKLTTSLSTNNMHLFDAEGRIKKYDTP 998

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEFFPLRL+YYE+RK +I           DNK RFI GV+ GEIIV          
Sbjct: 999  EQILEEFFPLRLDYYERRKNFILNDLERLLLVLDNKVRFILGVVSGEIIVSNRKNADLVL 1058

Query: 2096 XXXXXGFTPMPRK-------VAG-------ENDDNSEAEEDG---------YEYLLSLPI 2206
                 GFTPMP+K       VAG       E+D+NS  +E G         YEYLLS+ I
Sbjct: 1059 ELQQKGFTPMPKKGKSAEPVVAGANDEEEQEDDNNSTEQETGSVESAKRGDYEYLLSMSI 1118

Query: 2207 RTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2386
            RTLT                 F+ LK    +S                            
Sbjct: 1119 RTLTFESVQKLLGEKAEKEKEFEILKATPSKSMWLKDLDELEKKLDEIDSKDAEEERKRS 1178

Query: 2387 XLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSMEVGILKATPTN 2539
                         ATKAA+KPPQP KNTKK KN EP+   +SMEV  +    TN
Sbjct: 1179 TQATKKASNRALGATKAAKKPPQPRKNTKKAKNVEPENDSSSMEVENVAQVTTN 1232



 Score =  327 bits (837), Expect = 4e-89
 Identities = 174/279 (62%), Positives = 208/279 (74%), Gaps = 22/279 (7%)
 Frame = +2

Query: 65  KPPLRTSNAANIPSETF-----IFREMTQREHILRHPNIYVGSMEKHTQDLWVFKKDEIV 229
           K PL++S+AAN+ +        ++++ TQ EHIL  P+ YVGS+EKHTQ LWV++ DE+V
Sbjct: 6   KRPLQSSSAANVAAAAGKTIEEVYQKKTQLEHILLRPDTYVGSIEKHTQTLWVYENDEMV 65

Query: 230 YRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEVDQ 409
            R ISYVPGLYKIFD ILV+A DNK RDPSMD+LKVTID  +NTVSV++N +GVP E+ Q
Sbjct: 66  QRPISYVPGLYKIFDEILVNAADNKQRDPSMDALKVTIDAEQNTVSVFNNGDGVPIEIHQ 125

Query: 410 EEKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLKKY 538
           EEK YVPELI                   GRNGY GAKLT IFSTE +IETADG  LKKY
Sbjct: 126 EEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGY-GAKLTNIFSTEFVIETADGKRLKKY 184

Query: 539 KQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAWC 718
           KQ F+NNM  +S+P IT CK  ENWTKVTFKPDL KF M HLEEDVVALM+KRVLDMA C
Sbjct: 185 KQVFSNNMGKKSEPVITKCKAGENWTKVTFKPDLAKFRMDHLEEDVVALMKKRVLDMAGC 244

Query: 719 LGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
           LGK+VKVEL+G+L+    + SF  Y DL++KSAEKS+PV
Sbjct: 245 LGKTVKVELNGQLIR---MKSFRDYADLYLKSAEKSKPV 280



 Score = 73.6 bits (179), Expect = 3e-09
 Identities = 43/83 (51%), Positives = 51/83 (61%), Gaps = 20/83 (24%)
 Frame = +2

Query: 2549 KGKSVEPQV-----------DDNSEVQEDG---------YEYLLSVPIRTLTFEGFLKLL 2668
            KGKS EP V           D+NS  QE G         YEYLLS+ IRTLTFE   KLL
Sbjct: 1071 KGKSAEPVVAGANDEEEQEDDNNSTEQETGSVESAKRGDYEYLLSMSIRTLTFESVQKLL 1130

Query: 2669 ADKARMEKEFDILKATPTESLWM 2737
             +KA  EKEF+ILKATP++S+W+
Sbjct: 1131 GEKAEKEKEFEILKATPSKSMWL 1153


>ref|XP_003599271.2| DNA topoisomerase IV subunit A [Medicago truncatula]
 gb|AES69522.2| DNA topoisomerase IV subunit A [Medicago truncatula]
          Length = 1504

 Score =  601 bits (1549), Expect = 0.0
 Identities = 349/634 (55%), Positives = 395/634 (62%), Gaps = 38/634 (5%)
 Frame = +2

Query: 794  VDLHMKSA--EKSRPVNAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFN 967
            +D H K    E     NAIEL  AFS+KKAEDRK  +  FEPGT RD    L +YK+  +
Sbjct: 619  LDKHRKDFIWENELDGNAIEL--AFSKKKAEDRKNWMRSFEPGTCRDHEAKLISYKDFVD 676

Query: 968  KELILFSRADIQRSIPSMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHR 1147
            KELILFSRAD+QRSIPSMVDGLKP QRKI            + VGQFI YV EH  Y H 
Sbjct: 677  KELILFSRADLQRSIPSMVDGLKPGQRKILFCSFKKNLSKEVKVGQFIGYVSEHSAYHHG 736

Query: 1148 EPSLASTVVGMAQDFVGSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHE 1327
            E SLAST++GMAQDFVGSNNINLL PNGQFGTRN+GGKDH  SR IYT+LN VTR LFH 
Sbjct: 737  EQSLASTIIGMAQDFVGSNNINLLTPNGQFGTRNLGGKDHASSRYIYTQLNTVTRSLFHA 796

Query: 1328 NDDKLVSCEDEDGRSIEPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLL 1507
            +DDKL+   +EDGRSIEPNWYIPIIPLVLVNG+E    GW S+IP+YNPREIIAN++ LL
Sbjct: 797  DDDKLLEYLNEDGRSIEPNWYIPIIPLVLVNGSEGIGTGWSSFIPNYNPREIIANVRRLL 856

Query: 1508 KGENTVKMDPWYRGFTGTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFL 1687
              E  V MDPWY+GF GTIEKS KEG Y VNG+  EID  TF ITELPIR WTQDYK FL
Sbjct: 857  NDEEMVPMDPWYKGFRGTIEKSAKEGGYIVNGSVEEIDDITFRITELPIRKWTQDYKTFL 916

Query: 1688 ESITEGAPNVKDPLIEEFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSN 1867
            E  TEGAPNVKDPLIE+F++ G+ A VDI++RMK +K   I QEGL KKFKLT+TISTSN
Sbjct: 917  ELTTEGAPNVKDPLIEDFKQNGDDAIVDIEVRMKAEKVAAIMQEGLFKKFKLTSTISTSN 976

Query: 1868 MHLFDAKGKIKKFDNPEQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVL 2047
            MHLFDA+GKIKKFD PEQILEEF+PLRLEYYEKRK YI           DNK RFI GV+
Sbjct: 977  MHLFDAEGKIKKFDTPEQILEEFYPLRLEYYEKRKKYILANLERLLLILDNKVRFILGVV 1036

Query: 2048 KGEIIVRYSXXXXXXXXXXXXGFTPMPRK-------VAGENDDNSEAEEDG--------- 2179
             GEIIV               GFTP+P+K       VAG ND+NSE +ED          
Sbjct: 1037 SGEIIVSNRKRTELLIELKQKGFTPIPKKGKSAEPQVAGANDENSEDQEDSERETASKSV 1096

Query: 2180 ---------YEYLLSLPIRTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXX 2332
                     YEYLLSL I TLT                 F+ L   TP            
Sbjct: 1097 NVEGATWGDYEYLLSLSIGTLTLESVQKLLDEKADKENEFEIL-MGTPSKSLWLKDLDEL 1155

Query: 2333 XXXXXXXXXXXXXXXXXXXLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TS 2503
                                  N K   N  ATK A+KPPQP KNTKK  N EP+   +S
Sbjct: 1156 EKKLDELDRIEAEEGQKRSTMSNKK---NRLATKPAKKPPQPRKNTKKA-NVEPENDNSS 1211

Query: 2504 ME----VGILK----ATPTNTLCKGKSVEPQVDD 2581
            ME    V ++K    A P       K+ + + DD
Sbjct: 1212 MEIENAVEVVKPVEVAKPKGRAGSKKNAQTEADD 1245



 Score =  340 bits (873), Expect = 9e-94
 Identities = 181/277 (65%), Positives = 212/277 (76%), Gaps = 19/277 (6%)
 Frame = +2

Query: 59  MEKPPLRTSNAANIPSETF--IFREMTQREHILRHPNIYVGSMEKHTQDLWVFKKDEIVY 232
           MEK PL+ S  ANIPS+T   ++++ TQ EHIL  P+ YVGS+EKHTQ+LWV++ +E+V 
Sbjct: 1   MEKRPLQPSTTANIPSKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENEEMVN 60

Query: 233 RSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEVDQE 412
           RSISYVPGLYKIFD ILV+A DNK RDPSMDSLKVTIDP  NTVSVY+N +GVP E+ QE
Sbjct: 61  RSISYVPGLYKIFDEILVNAADNKQRDPSMDSLKVTIDPEANTVSVYNNGDGVPVEIHQE 120

Query: 413 EKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLKKYK 541
           EK YVPELI                   GRNGY GAKLT IFSTE +IETADG  LKKYK
Sbjct: 121 EKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGY-GAKLTNIFSTEFVIETADGRRLKKYK 179

Query: 542 QAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAWCL 721
           Q FT+NM  +SDP IT CK NENWTKVTFKPDLEKF+MT+LEEDVVALM+KRVLDMA CL
Sbjct: 180 QVFTDNMGKKSDPVITKCKANENWTKVTFKPDLEKFKMTYLEEDVVALMKKRVLDMAGCL 239

Query: 722 GKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRP 832
           GK+VKVEL+G ++      SF+ Y +L +K AEKS+P
Sbjct: 240 GKTVKVELNGTVIR---FKSFKDYAELFLKCAEKSKP 273



 Score = 66.6 bits (161), Expect = 4e-07
 Identities = 41/85 (48%), Positives = 48/85 (56%), Gaps = 22/85 (25%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQEDG------------------YEYLLSVPIRTLTFEGFLK 2662
            KGKS EPQV    D+NSE QED                   YEYLLS+ I TLT E   K
Sbjct: 1065 KGKSAEPQVAGANDENSEDQEDSERETASKSVNVEGATWGDYEYLLSLSIGTLTLESVQK 1124

Query: 2663 LLADKARMEKEFDILKATPTESLWM 2737
            LL +KA  E EF+IL  TP++SLW+
Sbjct: 1125 LLDEKADKENEFEILMGTPSKSLWL 1149


>ref|XP_020212372.1| DNA topoisomerase 2 [Cajanus cajan]
          Length = 1480

 Score =  595 bits (1535), Expect = 0.0
 Identities = 331/591 (56%), Positives = 383/591 (64%), Gaps = 25/591 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            NAIE+  AFS+KK EDRK  I +FEPG  RD  D   NY++  NKELILFSRAD+QRSIP
Sbjct: 638  NAIEM--AFSKKKTEDRKIWIRNFEPGNHRDHMDRYINYRDFVNKELILFSRADLQRSIP 695

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++ MAQDFV
Sbjct: 696  SMVDGLKPGQRKILFCSFKKKLFKEIKVGQFIGYVSEHSAYHHGEQSLASTIINMAQDFV 755

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  +R IYTELN  TRC+FHE+DDKL+   +EDG+SI
Sbjct: 756  GSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNTFTRCIFHEDDDKLLEYLNEDGKSI 815

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EPNWYIPIIPLVLVNG+E    GW SYIP+YNPR+IIAN++ LL GE  V M PWY+GF 
Sbjct: 816  EPNWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLSGETMVPMHPWYKGFK 875

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            G IE+S KEG Y VNG   E+D +TF ITELPIR WTQDYK+FLESIT+G+PNVKDPLIE
Sbjct: 876  GIIERSPKEGGYVVNGLVEEMDEQTFRITELPIRKWTQDYKQFLESITDGSPNVKDPLIE 935

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI++RMK DK   I QEGL KKFKLT+T+STSNMHLFDA+GKIKK++NP
Sbjct: 936  DFRQNGDDAIVDIEVRMKADKIAGIMQEGLLKKFKLTSTLSTSNMHLFDAEGKIKKYENP 995

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEFFPLRLEYYE+RK +I           DNK RFI GV+ GEIIV          
Sbjct: 996  EQILEEFFPLRLEYYERRKKHILENLERLLLVLDNKVRFILGVVNGEIIVSNRKKAELLI 1055

Query: 2096 XXXXXGFTPMPRK-------VAG----ENDDNSEAEED----------GYEYLLSLPIRT 2212
                 GFTPMPRK       VAG    ++DDN+  E++           YEYLLS+ I T
Sbjct: 1056 ELQQKGFTPMPRKGKSAEPQVAGADDEQDDDNNTREQETSSVEGAKRGDYEYLLSMSIGT 1115

Query: 2213 LTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXL 2392
            LT                 F+ LK  TP                                
Sbjct: 1116 LTLESVQKLLAEKDEKEKEFEILKA-TPSKSMWLKDLDELEKKLDESASKEAEEERKRSS 1174

Query: 2393 TYNYKGTANGCATKAAEKPPQPSKNTKKTKN-AEPD---TSMEVGILKATP 2533
              N K +  G    AA+KPPQP K TKK KN  EP+   + MEV  +   P
Sbjct: 1175 QANRKTSYRGETKAAAKKPPQPRKYTKKAKNVVEPENDNSPMEVENVAEVP 1225



 Score =  321 bits (822), Expect = 3e-87
 Identities = 170/281 (60%), Positives = 208/281 (74%), Gaps = 22/281 (7%)
 Frame = +2

Query: 59  MEKP-PLRTSNAANIPSETFIFREM----TQREHILRHPNIYVGSMEKHTQDLWVFKKDE 223
           M+ P PL +S+AAN+ +      EM    TQ EHIL  P+ YVGS+EKHTQ LWV++ DE
Sbjct: 1   MDHPRPLHSSSAANVAAAGKTIEEMYQKKTQLEHILLRPDTYVGSVEKHTQTLWVYENDE 60

Query: 224 IVYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEV 403
           +V+R +SYVPGLYKIFD ILV+A DNK RDPSMD+LKV +D  +NT++V++N +GVP E+
Sbjct: 61  MVHRPVSYVPGLYKIFDEILVNAADNKQRDPSMDALKVLVDAEQNTITVFNNGDGVPVEI 120

Query: 404 DQEEKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLK 532
            QEEK YVPELI                   GRNGY GAKLT IFSTE +IETADG   K
Sbjct: 121 HQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGY-GAKLTNIFSTEFVIETADGKRQK 179

Query: 533 KYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMA 712
           KYKQ F+NNM  +S+P IT CK  ENWTKVTFKPDLEKF+M +LEEDVVALM+KRV+DMA
Sbjct: 180 KYKQVFSNNMGKKSEPVITKCKSGENWTKVTFKPDLEKFKMAYLEEDVVALMKKRVVDMA 239

Query: 713 WCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
            CLGK+VKVEL+G+++    + SF  Y DL++KSAEKSRPV
Sbjct: 240 GCLGKTVKVELNGRVIK---MKSFRDYADLYLKSAEKSRPV 277



 Score = 68.2 bits (165), Expect = 1e-07
 Identities = 40/81 (49%), Positives = 49/81 (60%), Gaps = 18/81 (22%)
 Frame = +2

Query: 2549 KGKSVEPQV---------DDNSEVQEDG---------YEYLLSVPIRTLTFEGFLKLLAD 2674
            KGKS EPQV         D+N+  QE           YEYLLS+ I TLT E   KLLA+
Sbjct: 1068 KGKSAEPQVAGADDEQDDDNNTREQETSSVEGAKRGDYEYLLSMSIGTLTLESVQKLLAE 1127

Query: 2675 KARMEKEFDILKATPTESLWM 2737
            K   EKEF+ILKATP++S+W+
Sbjct: 1128 KDEKEKEFEILKATPSKSMWL 1148


>gb|KYP71391.1| DNA topoisomerase 2 [Cajanus cajan]
          Length = 1446

 Score =  590 bits (1521), Expect = 0.0
 Identities = 324/570 (56%), Positives = 371/570 (65%), Gaps = 4/570 (0%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            NAIE+  AFS+KK EDRK  I +FEPG  RD  D   NY++  NKELILFSRAD+QRSIP
Sbjct: 638  NAIEM--AFSKKKTEDRKIWIRNFEPGNHRDHMDRYINYRDFVNKELILFSRADLQRSIP 695

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SMVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++ MAQDFV
Sbjct: 696  SMVDGLKPGQRKILFCSFKKKLFKEIKVGQFIGYVSEHSAYHHGEQSLASTIINMAQDFV 755

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  +R IYTELN  TRC+FHE+DDKL+   +EDG+SI
Sbjct: 756  GSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNTFTRCIFHEDDDKLLEYLNEDGKSI 815

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EPNWYIPIIPLVLVNG+E    GW SYIP+YNPR+IIAN++ LL GE  V M PWY+GF 
Sbjct: 816  EPNWYIPIIPLVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLSGETMVPMHPWYKGFK 875

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            G IE+S KEG Y VNG   E+D +TF ITELPIR WTQDYK+FLESIT+G+PNVKDPLIE
Sbjct: 876  GIIERSPKEGGYVVNGLVEEMDEQTFRITELPIRKWTQDYKQFLESITDGSPNVKDPLIE 935

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI++RMK DK   I QEGL KKFKLT+T+STSNMHLFDA+GKIKK++NP
Sbjct: 936  DFRQNGDDAIVDIEVRMKADKIAGIMQEGLLKKFKLTSTLSTSNMHLFDAEGKIKKYENP 995

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEFFPLRLEYYE+RK +I           DNK RFI GV+ GEIIV          
Sbjct: 996  EQILEEFFPLRLEYYERRKKHILENLERLLLVLDNKVRFILGVVNGEIIVSNRKKAELLI 1055

Query: 2096 XXXXXGFTPMPRKVAGENDDNSEAEEDGYEYLLSLPIRTLTNXXXXXXXXXXXXXXXXFD 2275
                 GFTPMPRK               YEYLLS+ I TLT                 F+
Sbjct: 1056 ELQQKGFTPMPRK-------------GDYEYLLSMSIGTLTLESVQKLLAEKDEKEKEFE 1102

Query: 2276 SLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLTYNYKGTANGCATKAAEKPPQ 2455
             LK  TP                                  N K +  G    AA+KPPQ
Sbjct: 1103 ILKA-TPSKSMWLKDLDELEKKLDESASKEAEEERKRSSQANRKTSYRGETKAAAKKPPQ 1161

Query: 2456 PSKNTKKTKN-AEPD---TSMEVGILKATP 2533
            P K TKK KN  EP+   + MEV  +   P
Sbjct: 1162 PRKYTKKAKNVVEPENDNSPMEVENVAEVP 1191



 Score =  321 bits (822), Expect = 3e-87
 Identities = 170/281 (60%), Positives = 208/281 (74%), Gaps = 22/281 (7%)
 Frame = +2

Query: 59  MEKP-PLRTSNAANIPSETFIFREM----TQREHILRHPNIYVGSMEKHTQDLWVFKKDE 223
           M+ P PL +S+AAN+ +      EM    TQ EHIL  P+ YVGS+EKHTQ LWV++ DE
Sbjct: 1   MDHPRPLHSSSAANVAAAGKTIEEMYQKKTQLEHILLRPDTYVGSVEKHTQTLWVYENDE 60

Query: 224 IVYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEV 403
           +V+R +SYVPGLYKIFD ILV+A DNK RDPSMD+LKV +D  +NT++V++N +GVP E+
Sbjct: 61  MVHRPVSYVPGLYKIFDEILVNAADNKQRDPSMDALKVLVDAEQNTITVFNNGDGVPVEI 120

Query: 404 DQEEKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLK 532
            QEEK YVPELI                   GRNGY GAKLT IFSTE +IETADG   K
Sbjct: 121 HQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGY-GAKLTNIFSTEFVIETADGKRQK 179

Query: 533 KYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMA 712
           KYKQ F+NNM  +S+P IT CK  ENWTKVTFKPDLEKF+M +LEEDVVALM+KRV+DMA
Sbjct: 180 KYKQVFSNNMGKKSEPVITKCKSGENWTKVTFKPDLEKFKMAYLEEDVVALMKKRVVDMA 239

Query: 713 WCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
            CLGK+VKVEL+G+++    + SF  Y DL++KSAEKSRPV
Sbjct: 240 GCLGKTVKVELNGRVIK---MKSFRDYADLYLKSAEKSRPV 277


>ref|XP_014618555.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Glycine
            max]
          Length = 1481

 Score =  589 bits (1519), Expect = 0.0
 Identities = 327/581 (56%), Positives = 379/581 (65%), Gaps = 23/581 (3%)
 Frame = +2

Query: 839  AIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIPS 1018
            AIE+  AFS+KKAEDRK  I +FEPGT RD      NY++  NKELIL+SRAD+QRSIPS
Sbjct: 644  AIEM--AFSKKKAEDRKIWIRNFEPGTCRDHMAKYINYRDFVNKELILYSRADLQRSIPS 701

Query: 1019 MVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFVG 1198
            MVDGLKP QRKI            I VGQFI YV EH  Y H E SLAST++ MAQDFVG
Sbjct: 702  MVDGLKPGQRKILFCSFKKKLFKEIKVGQFIGYVSEHSAYHHGEQSLASTIINMAQDFVG 761

Query: 1199 SNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSIE 1378
            SNNINLLKPNGQFGTRN+GGKDH  +R IYTEL+ +TRC+FHE+DDKL+   +EDGR IE
Sbjct: 762  SNNINLLKPNGQFGTRNLGGKDHASARYIYTELSTITRCIFHEDDDKLLEYLNEDGRCIE 821

Query: 1379 PNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFTG 1558
            P WYIP+IPLVLVNG+E    GW SYIP+YNPR+IIAN++ LL GE  V MDPWY+GF G
Sbjct: 822  PTWYIPVIPLVLVNGSEGIGTGWSSYIPNYNPRDIIANVRRLLSGETMVPMDPWYKGFKG 881

Query: 1559 TIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIEE 1738
            TIE+S KEG Y VNG+  EI+   F ITELPIR WTQDYK+FLESIT+G+PNVKDPLI++
Sbjct: 882  TIERSPKEGGYIVNGSVEEINEHNFRITELPIRKWTQDYKQFLESITDGSPNVKDPLIDD 941

Query: 1739 FRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNPE 1918
            FR+ G+ A V+I++RMKL+K   I QEGL KKF LT++IST+NMHLFDA+GKIKK+DNPE
Sbjct: 942  FRQNGDDATVNIEVRMKLEKIVGIMQEGLLKKFXLTSSISTNNMHLFDAEGKIKKYDNPE 1001

Query: 1919 QILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXXX 2098
            QILEEFFPLRLEYYE+RK +I           DNK RFI GV+ GEIIV           
Sbjct: 1002 QILEEFFPLRLEYYERRKNHILNNLERLLLILDNKARFILGVVNGEIIVSNRKKADLLIE 1061

Query: 2099 XXXXGFTPMPRK-------VAGEN----DDNSEAEE---------DGYEYLLSLPIRTLT 2218
                GFTPMPRK       VAG N    DDN+  +E           YEYLLS+ I TLT
Sbjct: 1062 LQHKGFTPMPRKGKSAEPQVAGANEDQEDDNTREQETESVEVAKGGDYEYLLSMSIGTLT 1121

Query: 2219 NXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLTY 2398
                             F  LK  TP                                  
Sbjct: 1122 LEAVQKLLAEKAEKEKEFKILK-ETPSKSLWLKDLDELEKKLDDIDSIEAEEERKRSSQA 1180

Query: 2399 NYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSMEV 2512
            N K       TKAA+KPPQP K TKK KN EP+   +SMEV
Sbjct: 1181 NRK--TKEAFTKAAKKPPQPRKYTKKAKNVEPENDNSSMEV 1219



 Score =  315 bits (807), Expect = 3e-85
 Identities = 167/281 (59%), Positives = 208/281 (74%), Gaps = 24/281 (8%)
 Frame = +2

Query: 65  KPPLRTSNAANIPSE-------TFIFREMTQREHILRHPNIYVGSMEKHTQDLWVFKKDE 223
           K PL++S+AAN+ +          ++++ TQ EHIL  P+ YVGS+EKHTQ LWV++ DE
Sbjct: 6   KYPLQSSSAANVAATGGGKKTIEEMYQKKTQLEHILLRPDTYVGSVEKHTQTLWVYENDE 65

Query: 224 IVYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEV 403
           +V R++SYVPGLYKIFD ILV+A DNK RDPSMD+LKV+ID   NTVS+++N +GVP E+
Sbjct: 66  MVQRAVSYVPGLYKIFDEILVNAADNKQRDPSMDALKVSIDAEANTVSIFNNGDGVPVEI 125

Query: 404 DQEEKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLK 532
            QEEK YVPELI                   GRNGY GAKLT IFSTE +IETADG   K
Sbjct: 126 HQEEKVYVPELIFGHLLTSSNYNDNEKKTTGGRNGY-GAKLTNIFSTEFVIETADGKRQK 184

Query: 533 KYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMA 712
           KYKQ F++NM  +S+P IT CK  ENWTKVTFKPDLEKF+M +LEEDVVALM+KRV+DMA
Sbjct: 185 KYKQVFSDNMGKKSEPVITKCKVGENWTKVTFKPDLEKFKMDYLEEDVVALMKKRVVDMA 244

Query: 713 WCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
            CLGK+VKVEL+G+++    + SF  Y DL++KS EKSRPV
Sbjct: 245 GCLGKTVKVELNGQVIR---MKSFRDYADLYLKSVEKSRPV 282



 Score = 70.1 bits (170), Expect = 3e-08
 Identities = 42/80 (52%), Positives = 48/80 (60%), Gaps = 17/80 (21%)
 Frame = +2

Query: 2549 KGKSVEPQV--------DDNSEVQED---------GYEYLLSVPIRTLTFEGFLKLLADK 2677
            KGKS EPQV        DDN+  QE           YEYLLS+ I TLT E   KLLA+K
Sbjct: 1073 KGKSAEPQVAGANEDQEDDNTREQETESVEVAKGGDYEYLLSMSIGTLTLEAVQKLLAEK 1132

Query: 2678 ARMEKEFDILKATPTESLWM 2737
            A  EKEF ILK TP++SLW+
Sbjct: 1133 AEKEKEFKILKETPSKSLWL 1152


>ref|XP_015952953.1| DNA topoisomerase 2-like [Arachis duranensis]
          Length = 1483

 Score =  584 bits (1505), Expect = 0.0
 Identities = 317/572 (55%), Positives = 375/572 (65%), Gaps = 18/572 (3%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            +AIEL  AFS+KKAEDRKT I +FEPGT RD      +Y++  +KELILFSRAD+QRSIP
Sbjct: 650  DAIEL--AFSKKKAEDRKTWIRNFEPGTCRDHRAKHISYRDFVDKELILFSRADLQRSIP 707

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SM+DGLKP QRKI            I V QFI YV E   Y H E SLAST++GMAQDFV
Sbjct: 708  SMIDGLKPSQRKILFCSFKKKLTKEIKVAQFIGYVSEQSAYHHGEQSLASTIIGMAQDFV 767

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  +R IYTELNP+TR LF E+DD LV   +EDG+SI
Sbjct: 768  GSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNPITRRLFPEDDDNLVDYLNEDGKSI 827

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EPNWYIP+IPLVLVNG+E    GW SYIP+YNPREIIAN++ ++ GE  + MDPWYRG+ 
Sbjct: 828  EPNWYIPVIPLVLVNGSEGIGVGWSSYIPNYNPREIIANVRRMMNGETMIPMDPWYRGYK 887

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            GTIEKS KEG Y VNG   EI+ +TF ITELPIR WTQDYK+FLES+T+G+P VKDPLIE
Sbjct: 888  GTIEKSAKEGGYIVNGMVEEINEQTFRITELPIRKWTQDYKQFLESLTDGSPTVKDPLIE 947

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A +DI++RMKL+K  ++ QEGL KKFKL+++ISTSNMHLFDA+GKIKK+DNP
Sbjct: 948  DFRQNGDDATIDIEVRMKLEKVPMVMQEGLLKKFKLSSSISTSNMHLFDAEGKIKKYDNP 1007

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEFFPLRLEYY +RK Y            DNK RFI GV+ GEIIV          
Sbjct: 1008 EQILEEFFPLRLEYYVRRKKYKLDNLERVLLTLDNKVRFILGVVNGEIIVSNRRKADLLI 1067

Query: 2096 XXXXXGFTPMPRK-------VAGENDDNSEAEE-----------DGYEYLLSLPIRTLTN 2221
                 GFTPMPRK       VAG+NDDN E +E             YEYLLS+PI TLT 
Sbjct: 1068 ELKQKGFTPMPRKGKSAEPQVAGDNDDNPEEQETESVNVEGARVGDYEYLLSMPIGTLTL 1127

Query: 2222 XXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLTYN 2401
                            ++ LK   P+S                                N
Sbjct: 1128 ESVQKLLAEKDEKEKEYEILKATPPKSMWMEDLDQLEKKLDELETKEAEEERKRSSQA-N 1186

Query: 2402 YKGTANGCATKAAEKPPQPSKNTKKTKNAEPD 2497
             K +     TKA++KP Q  KN KK    E +
Sbjct: 1187 KKTSTRAVTTKASKKPRQ--KNIKKANVIEEE 1216



 Score =  313 bits (802), Expect = 1e-84
 Identities = 168/288 (58%), Positives = 212/288 (73%), Gaps = 30/288 (10%)
 Frame = +2

Query: 62  EKPPLRTSNAANIPSETF------------IFREMTQREHILRHPNIYVGSMEKHTQDLW 205
           +K PL++SN ANIP+ T             ++++ TQ EHIL  P+ YVGS+EKHTQ LW
Sbjct: 6   KKRPLQSSNNANIPTATAGNGNGDGKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQSLW 65

Query: 206 VFKKD-EIVYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNR 382
           V+ ++ E+V+RSI+YVPGLYKIFD ILV+A DNK RDPSM+S+KVTID  EN ++V++N 
Sbjct: 66  VYSENNEMVHRSITYVPGLYKIFDEILVNAADNKQRDPSMNSVKVTIDAEENLITVFNNG 125

Query: 383 NGVPEEVDQEEKAYVPELILD-----------------GRNGYGGAKLTIIFSTECIIET 511
           +GVP E+ QEEK YVPELI                   GRNGYG AKLT IFST+ IIET
Sbjct: 126 DGVPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYG-AKLTNIFSTQFIIET 184

Query: 512 ADGCHLKKYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMR 691
           ADG   KKYKQ F+ NM  +S+P IT CK  ENWTKV+FKPDL+KF+M++LEEDVVALM+
Sbjct: 185 ADGKRQKKYKQVFSENMGKKSEPSITKCKVGENWTKVSFKPDLDKFKMSYLEEDVVALMK 244

Query: 692 KRVLDMAWCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
           KRV+D+A CLGK+VKVEL+G+L+    I SF  Y DL++KSAEK+RPV
Sbjct: 245 KRVVDLAGCLGKTVKVELNGQLIR---IKSFREYADLYLKSAEKNRPV 289



 Score = 74.3 bits (181), Expect = 2e-09
 Identities = 43/78 (55%), Positives = 49/78 (62%), Gaps = 15/78 (19%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQED-----------GYEYLLSVPIRTLTFEGFLKLLADKAR 2683
            KGKS EPQV    DDN E QE             YEYLLS+PI TLT E   KLLA+K  
Sbjct: 1080 KGKSAEPQVAGDNDDNPEEQETESVNVEGARVGDYEYLLSMPIGTLTLESVQKLLAEKDE 1139

Query: 2684 MEKEFDILKATPTESLWM 2737
             EKE++ILKATP +S+WM
Sbjct: 1140 KEKEYEILKATPPKSMWM 1157


>ref|XP_016188028.1| DNA topoisomerase 2-like [Arachis ipaensis]
          Length = 1486

 Score =  583 bits (1503), Expect = 0.0
 Identities = 316/573 (55%), Positives = 376/573 (65%), Gaps = 18/573 (3%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            +AIEL  AFS+KKAEDRKT I +FEPGT RD      +Y++  +KELILFSRAD+QRSIP
Sbjct: 650  DAIEL--AFSKKKAEDRKTWIRNFEPGTCRDHRAKHISYRDFVDKELILFSRADLQRSIP 707

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
            SM+DGLKP QRKI            I V QFI YV E   Y H E SLAST++GMAQDFV
Sbjct: 708  SMIDGLKPSQRKILFCSFKKKLTKEIKVAQFIGYVSEQSAYHHGEQSLASTIIGMAQDFV 767

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGTRN+GGKDH  +R IYTELNP+TR LF E+DD LV   +EDG+SI
Sbjct: 768  GSNNINLLKPNGQFGTRNLGGKDHASARYIYTELNPITRRLFPEDDDNLVDYLNEDGKSI 827

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EPNWYIP+IPLVLVNG+E    GW SYIP+YNPR+IIAN++ ++ GE  + MDPWYRG+ 
Sbjct: 828  EPNWYIPVIPLVLVNGSEGIGVGWSSYIPNYNPRDIIANVRRMMNGETMIPMDPWYRGYK 887

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            GTIEKS KEG Y VNG   EI+ +TF ITELPIR WTQDYK+FLES+T+G+P VKDPLIE
Sbjct: 888  GTIEKSAKEGGYIVNGMVEEINEQTFRITELPIRKWTQDYKQFLESLTDGSPTVKDPLIE 947

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A +DI++RMKL+K  ++ QEGL KKFKL+++ISTSNMHLFDA+GKIKK+DNP
Sbjct: 948  DFRQNGDDATIDIEVRMKLEKVPMVMQEGLLKKFKLSSSISTSNMHLFDAEGKIKKYDNP 1007

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEFFPLRLEYY +RK Y            DNK RFI GV+ GEIIV          
Sbjct: 1008 EQILEEFFPLRLEYYVRRKKYKLDNLERVLLILDNKVRFILGVVNGEIIVSNRRKADLLI 1067

Query: 2096 XXXXXGFTPMPRK-------VAGENDDNSEAEE-----------DGYEYLLSLPIRTLTN 2221
                 GFTPMPRK       VAG+NDDN E +E             YEYLLS+PI +LT 
Sbjct: 1068 ELKQKGFTPMPRKGKSAEPQVAGDNDDNPEEQETESFNVEGARVGDYEYLLSMPIGSLTL 1127

Query: 2222 XXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLTYN 2401
                            ++ LK   P+S                                N
Sbjct: 1128 ESVQKLLAEKDEKEKEYEILKATPPKSMWMEDLDQLEKKLDELETKEAEEERKRSSQA-N 1186

Query: 2402 YKGTANGCATKAAEKPPQPSKNTKKTKNAEPDT 2500
             K +     TKA++KP Q  KN KK    E +T
Sbjct: 1187 KKTSTRAVTTKASKKPRQ--KNIKKANVIEEET 1217



 Score =  313 bits (802), Expect = 1e-84
 Identities = 168/288 (58%), Positives = 213/288 (73%), Gaps = 30/288 (10%)
 Frame = +2

Query: 62  EKPPLRTSNAANIPSETF------------IFREMTQREHILRHPNIYVGSMEKHTQDLW 205
           +K PL++SN ANIP+ T             ++++ TQ EHIL  P+ YVGS+EKHTQ LW
Sbjct: 6   KKRPLQSSNNANIPTATAGNGNGDGKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQSLW 65

Query: 206 VFKKD-EIVYRSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNR 382
           V+ ++ E+V+RSI+YVPGLYKIFD ILV+A DNK RDPSM+S+KVTID  EN ++V++N 
Sbjct: 66  VYSENNEMVHRSITYVPGLYKIFDEILVNAADNKQRDPSMNSVKVTIDAEENLITVFNNG 125

Query: 383 NGVPEEVDQEEKAYVPELILD-----------------GRNGYGGAKLTIIFSTECIIET 511
           +GVP E+ QEEK YVPELI                   GRNGYG AKLT IFST+ IIET
Sbjct: 126 DGVPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYG-AKLTNIFSTQFIIET 184

Query: 512 ADGCHLKKYKQAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMR 691
           ADG   KKYKQ F++NM  +S+P IT CK  ENWTKV+FKPDL+KF+M++LEEDVVALM+
Sbjct: 185 ADGKRQKKYKQVFSDNMGKKSEPAITKCKVGENWTKVSFKPDLDKFKMSYLEEDVVALMK 244

Query: 692 KRVLDMAWCLGKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
           KRV+D+A CLGK+VKVEL+G+L+    I SF  Y DL++KSAEK+RPV
Sbjct: 245 KRVVDLAGCLGKTVKVELNGQLIR---IKSFREYADLYLKSAEKNRPV 289



 Score = 72.8 bits (177), Expect = 5e-09
 Identities = 42/78 (53%), Positives = 49/78 (62%), Gaps = 15/78 (19%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQED-----------GYEYLLSVPIRTLTFEGFLKLLADKAR 2683
            KGKS EPQV    DDN E QE             YEYLLS+PI +LT E   KLLA+K  
Sbjct: 1080 KGKSAEPQVAGDNDDNPEEQETESFNVEGARVGDYEYLLSMPIGSLTLESVQKLLAEKDE 1139

Query: 2684 MEKEFDILKATPTESLWM 2737
             EKE++ILKATP +S+WM
Sbjct: 1140 KEKEYEILKATPPKSMWM 1157


>sp|O24308.1|TOP2_PEA RecName: Full=DNA topoisomerase 2; AltName: Full=DNA topoisomerase
            II; AltName: Full=PsTopII
 emb|CAA74891.1| topoisomerase II [Pisum sativum]
          Length = 1462

 Score =  571 bits (1472), Expect = e-177
 Identities = 331/619 (53%), Positives = 384/619 (62%), Gaps = 30/619 (4%)
 Frame = +2

Query: 836  NAIELLVAFSEKKAEDRKTSIPDFEPGTFRDRADLLRNYKNLFNKELILFSRADIQRSIP 1015
            NAIEL  AFS+KKAE RK  + +FEPGT RD    L NYK+  NKELILFSRAD+  S  
Sbjct: 634  NAIEL--AFSKKKAEGRKIWMRNFEPGTCRDHEAKLINYKDFVNKELILFSRADLFGSFK 691

Query: 1016 SMVDGLKPCQRKIXXXXXXXXXXXXINVGQFIAYVYEHFPYDHREPSLASTVVGMAQDFV 1195
              +                      I V QFI YV EH  Y H E SLAST++GMAQDFV
Sbjct: 692  KKL-------------------YKEIKVAQFIGYVSEHSAYHHGEQSLASTIIGMAQDFV 732

Query: 1196 GSNNINLLKPNGQFGTRNMGGKDHPKSRCIYTELNPVTRCLFHENDDKLVSCEDEDGRSI 1375
            GSNNINLLKPNGQFGT N+GGKDH  +R IYTEL+PVTRCLFHE+DDKL+   +EDG+SI
Sbjct: 733  GSNNINLLKPNGQFGTCNLGGKDHASARYIYTELSPVTRCLFHEHDDKLLEYLNEDGKSI 792

Query: 1376 EPNWYIPIIPLVLVNGNEATRAGWRSYIPSYNPREIIANMKHLLKGENTVKMDPWYRGFT 1555
            EPNWY+PIIPLVLVNG+E    GW SYIP+YNPREIIAN++ LL GE  V MDPWY+GF 
Sbjct: 793  EPNWYMPIIPLVLVNGSEGIGTGWSSYIPNYNPREIIANVRRLLNGEELVPMDPWYKGFR 852

Query: 1556 GTIEKSEKEGEYTVNGTTTEIDGRTFHITELPIRTWTQDYKRFLESITEGAPNVKDPLIE 1735
            GTIEKS KEG Y VNGT TEID +TF ITELPIR WTQDYK+FLESIT+GAPNVKDPLIE
Sbjct: 853  GTIEKSAKEGGYIVNGTVTEIDEQTFRITELPIRKWTQDYKQFLESITDGAPNVKDPLIE 912

Query: 1736 EFRKYGNYADVDIQIRMKLDKKDLITQEGLHKKFKLTTTISTSNMHLFDAKGKIKKFDNP 1915
            +FR+ G+ A VDI+I+MK +K   I QEGL KKFKLT+TISTSNMHLFDA+G  KKFD P
Sbjct: 913  DFRQNGDDAIVDIEIKMKPEKIATILQEGLFKKFKLTSTISTSNMHLFDAEGN-KKFDTP 971

Query: 1916 EQILEEFFPLRLEYYEKRKAYIXXXXXXXXXXXDNKERFISGVLKGEIIVRYSXXXXXXX 2095
            EQILEEFFPLRL+YYEK K YI           DNK RFI GV+ GEIIV          
Sbjct: 972  EQILEEFFPLRLDYYEKSKEYILGNLNRLLLILDNKVRFILGVVNGEIIVSNRKKAELLI 1031

Query: 2096 XXXXXGFTPMPRK-------VAGENDDNSEAEEDG------------------YEYLLSL 2200
                 GFTPMPRK       VAG NDD+SE +ED                   Y+ LLSL
Sbjct: 1032 ELKEKGFTPMPRKGKSTKPQVAGANDDDSEEQEDAEPETASQSVSVEGATWGDYDDLLSL 1091

Query: 2201 PIRTLTNXXXXXXXXXXXXXXXXFDSLKTRTPESXXXXXXXXXXXXXXXXXXXXXXXXXX 2380
            PI TLT                 ++ L + TP +                          
Sbjct: 1092 PIGTLTLESVQKLLDEKTEKEKEYEIL-SGTPTTSLWLKDLDEFEKKLDELDLKYAEDDR 1150

Query: 2381 XXXLTYNYKGTANGCATKAAEKPPQPSKNTKKTKNAEPD---TSMEV--GILKATPTNTL 2545
                  + K  ANG A+K A+KPPQP KNTKK K+ EP+   +SME+   +  A P    
Sbjct: 1151 KRASQGSKK--ANGFASKPAKKPPQPRKNTKKAKSVEPENDNSSMEIENAVEAAKPAEVA 1208

Query: 2546 CKGKSVEPQVDDNSEVQED 2602
                   P+ +   E ++D
Sbjct: 1209 KPKGRAAPKKNIQKEPEDD 1227



 Score =  343 bits (879), Expect = 1e-94
 Identities = 181/278 (65%), Positives = 213/278 (76%), Gaps = 19/278 (6%)
 Frame = +2

Query: 59  MEKPPLRTSNAANIPSETF--IFREMTQREHILRHPNIYVGSMEKHTQDLWVFKKDEIVY 232
           MEK PL+TSNAANIPS+T   ++++ TQ EHIL  P+ YVGS+EKHTQ+LWV++ DE+V+
Sbjct: 1   MEKRPLQTSNAANIPSKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDEMVH 60

Query: 233 RSISYVPGLYKIFDAILVDAVDNKLRDPSMDSLKVTIDPGENTVSVYHNRNGVPEEVDQE 412
           R++SYVPGLYKIFD ILV+A DNK RDPSMDSLKVTIDP  NTVSVY+N +GVP E+ QE
Sbjct: 61  RAVSYVPGLYKIFDEILVNAADNKQRDPSMDSLKVTIDPEANTVSVYNNGDGVPVEIHQE 120

Query: 413 EKAYVPELIL-----------------DGRNGYGGAKLTIIFSTECIIETADGCHLKKYK 541
           EK YVPELI                   GRNGY GAKLT IFSTE IIETADG  LKKYK
Sbjct: 121 EKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGY-GAKLTNIFSTEFIIETADGRRLKKYK 179

Query: 542 QAFTNNMEMESDPEITICKENENWTKVTFKPDLEKFEMTHLEEDVVALMRKRVLDMAWCL 721
           Q F+NNM  + +P IT CK +ENWTKVTFKPDLEKF+M +LEEDVVALM+KRVLDMA C 
Sbjct: 180 QVFSNNMGTKCEPVITKCKASENWTKVTFKPDLEKFKMAYLEEDVVALMKKRVLDMAGCF 239

Query: 722 GKSVKVELDGKLVGTGIINSFEHYVDLHMKSAEKSRPV 835
           GK+VKVEL+G L+      SF  Y DL +K AEKS+P+
Sbjct: 240 GKTVKVELNGTLIR---FKSFRDYADLFLKCAEKSKPM 274



 Score = 64.3 bits (155), Expect = 2e-06
 Identities = 39/85 (45%), Positives = 47/85 (55%), Gaps = 22/85 (25%)
 Frame = +2

Query: 2549 KGKSVEPQV----DDNSEVQEDG------------------YEYLLSVPIRTLTFEGFLK 2662
            KGKS +PQV    DD+SE QED                   Y+ LLS+PI TLT E   K
Sbjct: 1044 KGKSTKPQVAGANDDDSEEQEDAEPETASQSVSVEGATWGDYDDLLSLPIGTLTLESVQK 1103

Query: 2663 LLADKARMEKEFDILKATPTESLWM 2737
            LL +K   EKE++IL  TPT SLW+
Sbjct: 1104 LLDEKTEKEKEYEILSGTPTTSLWL 1128



 Score = 62.8 bits (151), Expect = 6e-06
 Identities = 29/34 (85%), Positives = 33/34 (97%)
 Frame = +2

Query: 3146 RNVGTKRTLGEKLLTDMLQPAEGTGTSPEKKVRK 3247
            R+VGTK++ G+KLLTDMLQPAEGTGTSPEKKVRK
Sbjct: 1338 RSVGTKQSAGQKLLTDMLQPAEGTGTSPEKKVRK 1371