BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Akebia24_contig00004052
         (3615 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002280960.2| PREDICTED: DNA topoisomerase 1-like [Vitis v...   604   e-169
emb|CAN67233.1| hypothetical protein VITISV_020021 [Vitis vinifera]   601   e-169
ref|XP_004291220.1| PREDICTED: DNA topoisomerase 1-like [Fragari...   560   e-156
gb|EXC32749.1| DNA topoisomerase 1 [Morus notabilis]                  549   e-153
ref|XP_006483647.1| PREDICTED: uncharacterized protein LOC102624...   537   e-149
ref|XP_006483648.1| PREDICTED: uncharacterized protein LOC102624...   536   e-149
ref|XP_006483646.1| PREDICTED: uncharacterized protein LOC102624...   536   e-149
ref|XP_007011466.1| DNA topoisomerase isoform 5 [Theobroma cacao...   530   e-147
ref|XP_007011465.1| DNA topoisomerase isoform 4 [Theobroma cacao...   530   e-147
ref|XP_007011464.1| DNA topoisomerase isoform 3 [Theobroma cacao...   530   e-147
ref|XP_007011463.1| DNA topoisomerase isoform 2 [Theobroma cacao...   530   e-147
ref|XP_004136444.1| PREDICTED: DNA topoisomerase 1-like [Cucumis...   529   e-147
ref|XP_006450082.1| hypothetical protein CICLE_v10007345mg [Citr...   528   e-147
ref|XP_007225278.1| hypothetical protein PRUPE_ppa001428mg [Prun...   525   e-146
ref|XP_002528003.1| prokaryotic DNA topoisomerase, putative [Ric...   525   e-146
ref|XP_004233765.1| PREDICTED: DNA topoisomerase 1-like [Solanum...   525   e-146
ref|XP_007011462.1| DNA topoisomerase isoform 1 [Theobroma cacao...   519   e-144
ref|XP_007158787.1| hypothetical protein PHAVU_002G181900g [Phas...   515   e-143
ref|XP_006382211.1| hypothetical protein POPTR_0006s29400g [Popu...   513   e-142
ref|XP_006601080.1| PREDICTED: DNA topoisomerase 3-alpha-like is...   513   e-142

>ref|XP_002280960.2| PREDICTED: DNA topoisomerase 1-like [Vitis vinifera]
          Length = 1185

 Score =  604 bits (1557), Expect = e-169
 Identities = 367/689 (53%), Positives = 434/689 (62%), Gaps = 26/689 (3%)
 Frame = +2

Query: 1625 LQCRTLEKYPGTFLPYSPFLSVGKYGKCTQLAFRKKGETGRLTKDKLIGLRFKVERDTRP 1804
            LQ R  + YP T LP +      K+G  +Q+ FRK G    +   +   LR  V R+   
Sbjct: 33   LQYRGFQNYPATSLPCTRLNGGDKFGNFSQINFRKIGIPALVNNIQPKILRLNVNRNFHI 92

Query: 1805 FKSCNGEHRQSQSVTFQTQLQFGFPCTMKYVRNFTSRCLEISFRLDSPSYECFGRRFFSI 1984
            F S     R +  V  Q+QL+ GFP  +  +       L+I  R  SP Y+   +R FS 
Sbjct: 93   FGSLTDSSRFA--VPVQSQLRLGFPNAVTPIYG----TLDIGIRFSSPYYKALAKRPFS- 145

Query: 1985 NAPQKSQFPRKSTNVNNNNASIRDGKSGGNNYSFKRPQRFQKQVKSSTAVRSSSFDEA-- 2158
                  Q PR       +N  IRDG +  N   FK   + +K  KS TA R S F+ A  
Sbjct: 146  ------QVPRVKNK--GDNLGIRDG-TAENTSLFKPFNKHRKWEKSLTAHRRS-FNGAVR 195

Query: 2159 -----HXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESKPSISTPAKNNSN----- 2308
                                     M    Q+  N  K+A+  PSIST   +N+N     
Sbjct: 196  AAGSNQPTKVSSSSSRRSALGDGDMMTQQEQLVDNGRKDADLSPSISTSPVSNNNRGSKA 255

Query: 2309 --DQVTKLGNKKHEEQLSG----SGVAKTKGSKQASRAKKPIVTKAGQFSQSSE------ 2452
               Q  +   KK++EQ++     S VA+ K +K +S A K  +TK  Q  Q+S+      
Sbjct: 256  TEKQRKQSRTKKNKEQVTSTDASSDVAQKKSTKSSSEANKSNITKKSQSPQASKNNSTGN 315

Query: 2453 --ILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPVEVNKKPPG 2626
              +  ++ +     QSKK  GSS                N   KK       ++ K    
Sbjct: 316  KPVEALDSSVSTKSQSKKATGSSNKKGKSPKVA------NESPKKQTVHTMGKI-KSLEQ 368

Query: 2627 RKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRSGSVRPDDGFS 2806
            R LK LYP  GKSVVVVES+TKAKVIQGYLGDM+EVLPSYGHVRDLAGRSGSVRPDD FS
Sbjct: 369  RPLKKLYPSSGKSVVVVESVTKAKVIQGYLGDMYEVLPSYGHVRDLAGRSGSVRPDDDFS 428

Query: 2807 MVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQDALHENINVA 2986
            MVWEVPSAAWTHLKSIKVAL GAENLILASDPDREGEAIAWHI EML QQDALH+++ VA
Sbjct: 429  MVWEVPSAAWTHLKSIKVALGGAENLILASDPDREGEAIAWHIIEMLLQQDALHKDLTVA 488

Query: 2987 RVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWRKLPGCQSAGR 3166
            RVVFHEITESSIKSAL APR+I+ NLVHAYLARR+LDYLIGF+ISPLLWRKLPGCQSAGR
Sbjct: 489  RVVFHEITESSIKSALDAPREIDVNLVHAYLARRALDYLIGFNISPLLWRKLPGCQSAGR 548

Query: 3167 VQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLTHFNFKKLEQL 3346
            VQSAALALICDREM+IDEFKPQEYW+VEVEFNRK+   +   F FPS+LTHF+ KKL Q 
Sbjct: 549  VQSAALALICDREMEIDEFKPQEYWTVEVEFNRKQGSSMNSKF-FPSYLTHFDSKKLNQF 607

Query: 3347 SISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDAANKFNFSASYTMK 3526
            SISS  E K IE++I S  F V+GSK +K RKNP  PYITSTLQQDAANK +FSA YTMK
Sbjct: 608  SISSHTEAKAIEQEINSLEFKVIGSKRNKMRKNPPTPYITSTLQQDAANKLHFSAMYTMK 667

Query: 3527 VAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            +AQ+LYEGV+LSD +A GLITYMRTDGLH
Sbjct: 668  LAQRLYEGVQLSDGKAAGLITYMRTDGLH 696


>emb|CAN67233.1| hypothetical protein VITISV_020021 [Vitis vinifera]
          Length = 1039

 Score =  601 bits (1549), Expect = e-169
 Identities = 367/702 (52%), Positives = 433/702 (61%), Gaps = 39/702 (5%)
 Frame = +2

Query: 1625 LQCRTLEKYPGTFLPYSPFLSVGKYGKCTQLAFRKKGETGRLTKDKLIGLRFKVERDTRP 1804
            LQ R  + YP T LPY+      K+G  +Q+ FRK G    +   +   LR    R+   
Sbjct: 33   LQYRGFQNYPATSLPYTRVNGGDKFGNFSQINFRKIGIPALVNNIQPKILRLNANRNFHI 92

Query: 1805 FKSCNGEHRQSQSVTFQTQLQFGFPCTMKYVRNFTSRCLEISFRLDSPSYECFGRRFFSI 1984
            F S     R +  V  Q+QL+ GFP  +  +       L+I  R  SP Y+   +R FS 
Sbjct: 93   FGSLTDSSRFA--VPVQSQLRLGFPNAVTPIYG----TLDIGIRFSSPYYKALAKRPFS- 145

Query: 1985 NAPQKSQFPRKSTNVNNNNASIRDGKSGGNNYSFKRPQRFQKQVKSSTAVRSSSFDEA-- 2158
                  Q PR       +N  IRDG +  N   FK   + +K  KS TA R S F+ A  
Sbjct: 146  ------QVPRVKNK--GDNLGIRDG-TAENTSLFKPFNKHRKWEKSLTAHRRS-FNGAVR 195

Query: 2159 -----HXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESKPSISTPAKNNSN----- 2308
                                     M    Q+  N  K+ +  PSIST   +N+N     
Sbjct: 196  AAGSNQPTKVSSSSSRRSALSDGDMMTQQEQLVDNGRKDVDLSPSISTSPVSNNNRGSKA 255

Query: 2309 --DQVTKLGNKKHEEQLSG----SGVAKTKGSKQASRAKKPIVTKAGQFSQSSEILQV-- 2464
               Q  +   KK++EQ++     S VA+ K +K +S A K  +TK  Q  Q+S++  V  
Sbjct: 256  TEKQRKQSRTKKNKEQVTSTDASSDVAQKKSTKSSSEANKSNITKKSQSPQASKVRHVSI 315

Query: 2465 -------------------EETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHH 2587
                               + +     QSKK  GSS                N   KK  
Sbjct: 316  CIYELFQNNSTGNKPVEALDSSVSTKSQSKKATGSSNKKGKSPKVA------NESPKKQT 369

Query: 2588 SAVPVEVNKKPPGRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLA 2767
                 ++ K    R LK LYP  GKSVVVVES+TKAKVIQGYLGDM+EVLPSYGHVRDLA
Sbjct: 370  VHTMGKI-KSLEQRPLKKLYPSSGKSVVVVESVTKAKVIQGYLGDMYEVLPSYGHVRDLA 428

Query: 2768 GRSGSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEML 2947
            GRSGSVRPDD FSMVWEVPSAAWTHLKSIKVAL GAENLILASDPDREGEAIAWHI EML
Sbjct: 429  GRSGSVRPDDDFSMVWEVPSAAWTHLKSIKVALGGAENLILASDPDREGEAIAWHIIEML 488

Query: 2948 QQQDALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPL 3127
             QQDALH+++ VARVVFHEITESSIKSAL APR+I+ NLVHAYLARR+LDYLIGF+ISPL
Sbjct: 489  LQQDALHKDLTVARVVFHEITESSIKSALDAPREIDVNLVHAYLARRALDYLIGFNISPL 548

Query: 3128 LWRKLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPS 3307
            LWRKLPGCQSAGRVQSAALALICDREM+IDEFKPQEYW+VEVEFNRK+   +   F FPS
Sbjct: 549  LWRKLPGCQSAGRVQSAALALICDREMEIDEFKPQEYWTVEVEFNRKQGSSMNSKF-FPS 607

Query: 3308 HLTHFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDA 3487
            +LTHF+ KKL Q SISS  E K IE++I S  F V+GSK +K RKNP  PYITSTLQQDA
Sbjct: 608  YLTHFDSKKLNQFSISSHTEAKAIEQEINSLEFKVIGSKRNKMRKNPPTPYITSTLQQDA 667

Query: 3488 ANKFNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            ANK +FSA YTMK+AQ+LYEGV+LSD +A GLITYMRTDGLH
Sbjct: 668  ANKLHFSAMYTMKLAQRLYEGVQLSDGKAAGLITYMRTDGLH 709


>ref|XP_004291220.1| PREDICTED: DNA topoisomerase 1-like [Fragaria vesca subsp. vesca]
          Length = 1175

 Score =  560 bits (1442), Expect = e-156
 Identities = 337/671 (50%), Positives = 416/671 (61%), Gaps = 8/671 (1%)
 Frame = +2

Query: 1625 LQCRTLEKYPGTFLPYSPFLSVGKYGKCTQLAFRKKGETGRLTKDKLIGLRFKVERDTRP 1804
            LQCR LE  PGT LP SP LS+ K    ++L FRK   +  +T         K      P
Sbjct: 41   LQCRALENCPGTCLPSSPVLSLNKCRNYSRLRFRKSRVSCMITS-----YGAKAGPTFAP 95

Query: 1805 FKSCNGEHRQSQSVTFQTQLQ----FGFPCTMKYVRNFTSRCLEISFRLDSPSYECFGRR 1972
             +      + + S+  Q +L      G    M   R F       S  LDS   + + +R
Sbjct: 96   LRRSGDVFQGAFSIDSQLRLSAVNALGTANVMS--RGFLGNGCRSSL-LDSRVGD-YSKR 151

Query: 1973 FFSINAPQKSQFPRKSTNVNNNNASIRDGKSGGNNYSFKRPQRFQKQVKSSTAVRSSSFD 2152
            F S    Q      K  NV + +   +  K   N    K+    Q + +++ +  S   D
Sbjct: 152  FLS----QVPDVTSKVENVGSQDGRRKWFKMISNRKKLKKALATQSETEATVSSISKDAD 207

Query: 2153 EAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESKPS-ISTP-AKNNSNDQVTKL 2326
                                   K + ++  ++  +  SK   +S P AK  S  + TK 
Sbjct: 208  -----------VKVSNETQVGNEKEDEKLESSISNSPISKTKEVSKPKAKRRSKSKKTK- 255

Query: 2327 GNKKHEEQLSGSGVAKTKGSKQASRAKKPIVTKAGQFSQSSEILQVEETTLIPEQSKKTV 2506
              ++     + + VA T+ S+  S+ KK   +K G+ S   + L     T + + + ++ 
Sbjct: 256  --EQDSATNAVADVASTQSSESTSQTKKSGRSKKGEKSAQDKGLSATVKTPV-DLANRSS 312

Query: 2507 GSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPVEVNKKPPGRKL--KPLYPPRGKSVVVVE 2680
                             S N   K     +P E+ K  P  K+  K LYP  GK+VVVVE
Sbjct: 313  TKPRRNKKGEKDSEKEKSINSAAKSPQKLIPQEMGKLKPYGKITTKQLYPATGKTVVVVE 372

Query: 2681 SLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRSGSVRPDDGFSMVWEVPSAAWTHLKSIKV 2860
            S+TKAKVIQGYLGDMFEVLPSYGHVRDLA RSGSVRPDD FSMVWEVPSAAWTHLKSIKV
Sbjct: 373  SVTKAKVIQGYLGDMFEVLPSYGHVRDLAARSGSVRPDDDFSMVWEVPSAAWTHLKSIKV 432

Query: 2861 ALNGAENLILASDPDREGEAIAWHITEMLQQQDALHENINVARVVFHEITESSIKSALQA 3040
            AL+GAENLILASDPDREGEAIAWHI EMLQQQDAL ++INVARVVFHEITE+SIKSALQA
Sbjct: 433  ALSGAENLILASDPDREGEAIAWHIIEMLQQQDALRKDINVARVVFHEITEASIKSALQA 492

Query: 3041 PRDINANLVHAYLARRSLDYLIGFSISPLLWRKLPGCQSAGRVQSAALALICDREMDIDE 3220
            PR+I+ NLVHAYLARR+LDYLIGF+ISPLLWRKLP CQSAGRVQSAALAL+CDREM+ID+
Sbjct: 493  PREIDQNLVHAYLARRALDYLIGFNISPLLWRKLPSCQSAGRVQSAALALVCDREMEIDK 552

Query: 3221 FKPQEYWSVEVEFNRKEPERLEKSFSFPSHLTHFNFKKLEQLSISSQAEVKDIEEKITSS 3400
            FKPQEYW++++E N+ EP     + S P+HLTHF+ KKL+Q SISS  E KDIE++I S 
Sbjct: 553  FKPQEYWTIDIELNQNEPGSSVNAISLPAHLTHFDSKKLDQFSISSHTEAKDIEQQINSE 612

Query: 3401 SFVVVGSKMSKSRKNPLAPYITSTLQQDAANKFNFSASYTMKVAQKLYEGVKLSDDEATG 3580
            +F V+ SK +K RKNP  PYITSTLQQDAANK +FSASYTMK+AQKLYEGV+LSD +A G
Sbjct: 613  TFKVISSKKNKLRKNPPTPYITSTLQQDAANKLHFSASYTMKLAQKLYEGVQLSDGKAAG 672

Query: 3581 LITYMRTDGLH 3613
            LITY RTDGLH
Sbjct: 673  LITYTRTDGLH 683


>gb|EXC32749.1| DNA topoisomerase 1 [Morus notabilis]
          Length = 1163

 Score =  549 bits (1415), Expect = e-153
 Identities = 334/690 (48%), Positives = 424/690 (61%), Gaps = 27/690 (3%)
 Frame = +2

Query: 1625 LQCRTLEKYPGTFLPYSPFLSVGKYGKCTQLAFRKKGETGRLTKDKLIGLRFKVERDTRP 1804
            LQ R L  Y GT LP S F +  K  K   + F+ K     L  +       KV ++  P
Sbjct: 34   LQLRALHNYTGTCLPCSSFGASNKCRKSALIRFKNKSFPCTLRTEHT-----KVGKEFYP 88

Query: 1805 FKSCNGEHRQSQSVTFQTQLQFGFPCTMKYVRNFTSRCLEISFRLDSPSYECFGRRFFSI 1984
             +S +           Q+ L+ GF  T   V NF+            PSY  F +RFFS 
Sbjct: 89   LRSFSDGP--------QSNLRPGFGNTFGPVNNFSYVSFNEGVSSSLPSYGAFTKRFFS- 139

Query: 1985 NAPQKSQFPRKSTNVNNNNASIRDGKSGGNNYSFKRPQRFQKQVKS------STAVRSSS 2146
               QK             N   +DG+SGG+  + +   + +KQ K+      + A  SSS
Sbjct: 140  ---QKKL----------ENRGAQDGESGGSASALRMISKRRKQAKALAANGKTGATGSSS 186

Query: 2147 FDEAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESKPSISTPAKNNSNDQVTKL 2326
              E                     +       G   K  ES    S P     N++V K 
Sbjct: 187  SKE----------------ISLDALSEPLVGGGKDSKILES----SVPTSPVGNNEVPKA 226

Query: 2327 GNKKH-------EEQLSGSGVAK---TKGSKQASRAKKPIVTKAGQ-----------FSQ 2443
              KK        ++ ++ S + K    KG++  SRAKK  + K+ Q            S+
Sbjct: 227  SRKKKLRSKKSTKQDVADSSLLKDDAAKGARGTSRAKKSSIGKSKQEPLQAPKLNLNGSR 286

Query: 2444 SSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPVEVNKKPP 2623
            S+EI     ++  P  SKK+  SS                   + + H A  V   K P 
Sbjct: 287  SAEIADSSSSSTKPLSSKKSGKSSSKEKPGKAAE--------KSSQKHKAQQVGQVKCPG 338

Query: 2624 GRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRSGSVRPDDGF 2803
               LKPLYPP GKSVVVVES+TKAKVIQGYLGDM+EVLPSYGHVRDLA +SGSVRP++ F
Sbjct: 339  KMSLKPLYPPIGKSVVVVESVTKAKVIQGYLGDMYEVLPSYGHVRDLARKSGSVRPEEDF 398

Query: 2804 SMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQDALHENINV 2983
            SMVWEVPSA+W+HLKSIKVAL+GAENLILASDPDREGEAIAWHI EML QQD+L +N  V
Sbjct: 399  SMVWEVPSASWSHLKSIKVALSGAENLILASDPDREGEAIAWHIIEMLHQQDSLQKNTTV 458

Query: 2984 ARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWRKLPGCQSAG 3163
            ARVVFHEITESSIK AL+ PR+++ NLVHAYLARR+LDYLIGF+ISPLLWRKLPGCQSAG
Sbjct: 459  ARVVFHEITESSIKRALETPRELDENLVHAYLARRALDYLIGFNISPLLWRKLPGCQSAG 518

Query: 3164 RVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLTHFNFKKLEQ 3343
            RVQSAALALICDRE++ D+F+PQEYWS++VEF++++   +  +++F +HLTH++F +L Q
Sbjct: 519  RVQSAALALICDREIETDQFEPQEYWSIDVEFHKEDLGSV--NYAFQAHLTHYDFNRLNQ 576

Query: 3344 LSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDAANKFNFSASYTM 3523
            L+ISS A  K+IE ++TS++F VV SKM+K RKNP +PYITSTLQQDA+NK +FS++YTM
Sbjct: 577  LAISSHAYAKEIENQVTSANFKVVKSKMNKMRKNPPSPYITSTLQQDASNKLHFSSTYTM 636

Query: 3524 KVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            K+AQKLYEG++LSD +A GLITYMRTDG H
Sbjct: 637  KLAQKLYEGIQLSDGKAAGLITYMRTDGCH 666


>ref|XP_006483647.1| PREDICTED: uncharacterized protein LOC102624144 isoform X2 [Citrus
            sinensis]
          Length = 1159

 Score =  537 bits (1384), Expect = e-149
 Identities = 317/570 (55%), Positives = 372/570 (65%), Gaps = 5/570 (0%)
 Frame = +2

Query: 1919 LEISFRLDSPSYECFGRRFFSINAPQKSQFPRKSTNVNNNNAS-IRDGKSGGNNYSFKRP 2095
            L+   R  S + E F +R FS       Q  R    +     S  R G  GG ++  K  
Sbjct: 118  LDNGIRFSSLNCEPFSKRCFS-------QLSRGKIGIEKIGVSDARSGSGGGKSWFNKHR 170

Query: 2096 QRFQK-QVKSSTAVRSSSFDEAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESK 2272
            +R      +  +   SSS   +                     K  + VS N ++N  SK
Sbjct: 171  KRNNAVSARGKSNATSSSISVSEDVNAVNSTSEQLVGDGVEGTKLGSSVS-NTKQN--SK 227

Query: 2273 PSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAKTKGSKQASRAK-KPIVTKAGQFSQSS 2449
            P      ++ S  +  +L      EQ S     K+    ++S+ K K       + S  +
Sbjct: 228  PRARQQQQSRSKKKKEQLSATVASEQASVGKSCKSVSLAKSSKCKSKQCADLTSETSPGN 287

Query: 2450 EILQ-VEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPVEVNKKPPG 2626
             + Q +  + L  +QSKK  G+                    T +    VP   N +   
Sbjct: 288  TLEQPLASSALTKQQSKKNSGNCGRKKKSAKATKASLQRQ--TSEEMVIVPRGQNTQ--- 342

Query: 2627 RKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRSGSVRPDDGFS 2806
                PLYPP GKSVVVVES+TKAKVIQGYLGDM+EVLPSYGHVRDLA RSGSVRPDD FS
Sbjct: 343  ---NPLYPPSGKSVVVVESVTKAKVIQGYLGDMYEVLPSYGHVRDLAARSGSVRPDDDFS 399

Query: 2807 MVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQDALHENINVA 2986
            MVWEVPSAAWTHLKSIKVAL+GAENLILASDPDREGEAIAWHI EMLQQQDALHENI VA
Sbjct: 400  MVWEVPSAAWTHLKSIKVALSGAENLILASDPDREGEAIAWHIVEMLQQQDALHENITVA 459

Query: 2987 RVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWRKLPGCQSAGR 3166
            RVVFHEITE+SIK ALQAPR+I+ANLV AYLARR+LDYLIGF+ISPLLWRKLPGCQSAGR
Sbjct: 460  RVVFHEITEASIKVALQAPREIDANLVQAYLARRALDYLIGFNISPLLWRKLPGCQSAGR 519

Query: 3167 VQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLTHFNFKKLEQL 3346
            VQSAAL+LICDREM+IDEFKPQEYW+VE   ++KE   L+ +FSFP+HLTHF  K+L QL
Sbjct: 520  VQSAALSLICDREMEIDEFKPQEYWTVEAVLDKKESHSLD-TFSFPAHLTHFQSKRLNQL 578

Query: 3347 SISSQAEVKDIEEKITSSSF-VVVGSKMSKSRKNPLAPYITSTLQQDAANKFNFSASYTM 3523
            SISS  E KDIE+KI S++F V+  SK S  RKNP  PYITSTLQQDAANK NFSA+YTM
Sbjct: 579  SISSHTEAKDIEQKINSANFQVIKNSKRSMVRKNP-TPYITSTLQQDAANKLNFSATYTM 637

Query: 3524 KVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            K+AQKLYEGV+L D+ A GLITYMRTDGLH
Sbjct: 638  KLAQKLYEGVQLPDETAAGLITYMRTDGLH 667


>ref|XP_006483648.1| PREDICTED: uncharacterized protein LOC102624144 isoform X3 [Citrus
            sinensis]
          Length = 1158

 Score =  536 bits (1380), Expect = e-149
 Identities = 316/571 (55%), Positives = 371/571 (64%), Gaps = 6/571 (1%)
 Frame = +2

Query: 1919 LEISFRLDSPSYECFGRRFFSINAPQKSQFPRKSTNVNNNNAS-IRDGKSGGNNYSFKRP 2095
            L+   R  S + E F +R FS       Q  R    +     S  R G  GG ++  K  
Sbjct: 116  LDNGIRFSSLNCEPFSKRCFS-------QLSRGKIGIEKIGVSDARSGSGGGKSWFNKHR 168

Query: 2096 QRFQK-QVKSSTAVRSSSFDEAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESK 2272
            +R      +  +   SSS   +                     K  + VS N ++N  SK
Sbjct: 169  KRNNAVSARGKSNATSSSISVSEDVNAVNSTSEQLVGDGVEGTKLGSSVS-NTKQN--SK 225

Query: 2273 PSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAKTKGSKQASRAK-KPIVTKAGQFSQSS 2449
            P      ++ S  +  +L      EQ S     K+    ++S+ K K       + +   
Sbjct: 226  PRARQQQQSRSKKKKEQLSATVASEQASVGKSCKSVSLAKSSKCKSKQCADLTSEKTSPG 285

Query: 2450 EILQ--VEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPVEVNKKPP 2623
              L+  +  + L  +QSKK  G+                    T +    VP   N +  
Sbjct: 286  NTLEQPLASSALTKQQSKKNSGNCGRKKKSAKATKASLQRQ--TSEEMVIVPRGQNTQ-- 341

Query: 2624 GRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRSGSVRPDDGF 2803
                 PLYPP GKSVVVVES+TKAKVIQGYLGDM+EVLPSYGHVRDLA RSGSVRPDD F
Sbjct: 342  ----NPLYPPSGKSVVVVESVTKAKVIQGYLGDMYEVLPSYGHVRDLAARSGSVRPDDDF 397

Query: 2804 SMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQDALHENINV 2983
            SMVWEVPSAAWTHLKSIKVAL+GAENLILASDPDREGEAIAWHI EMLQQQDALHENI V
Sbjct: 398  SMVWEVPSAAWTHLKSIKVALSGAENLILASDPDREGEAIAWHIVEMLQQQDALHENITV 457

Query: 2984 ARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWRKLPGCQSAG 3163
            ARVVFHEITE+SIK ALQAPR+I+ANLV AYLARR+LDYLIGF+ISPLLWRKLPGCQSAG
Sbjct: 458  ARVVFHEITEASIKVALQAPREIDANLVQAYLARRALDYLIGFNISPLLWRKLPGCQSAG 517

Query: 3164 RVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLTHFNFKKLEQ 3343
            RVQSAAL+LICDREM+IDEFKPQEYW+VE   ++KE   L+ +FSFP+HLTHF  K+L Q
Sbjct: 518  RVQSAALSLICDREMEIDEFKPQEYWTVEAVLDKKESHSLD-TFSFPAHLTHFQSKRLNQ 576

Query: 3344 LSISSQAEVKDIEEKITSSSF-VVVGSKMSKSRKNPLAPYITSTLQQDAANKFNFSASYT 3520
            LSISS  E KDIE+KI S++F V+  SK S  RKNP  PYITSTLQQDAANK NFSA+YT
Sbjct: 577  LSISSHTEAKDIEQKINSANFQVIKNSKRSMVRKNP-TPYITSTLQQDAANKLNFSATYT 635

Query: 3521 MKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            MK+AQKLYEGV+L D+ A GLITYMRTDGLH
Sbjct: 636  MKLAQKLYEGVQLPDETAAGLITYMRTDGLH 666


>ref|XP_006483646.1| PREDICTED: uncharacterized protein LOC102624144 isoform X1 [Citrus
            sinensis]
          Length = 1160

 Score =  536 bits (1380), Expect = e-149
 Identities = 316/571 (55%), Positives = 371/571 (64%), Gaps = 6/571 (1%)
 Frame = +2

Query: 1919 LEISFRLDSPSYECFGRRFFSINAPQKSQFPRKSTNVNNNNAS-IRDGKSGGNNYSFKRP 2095
            L+   R  S + E F +R FS       Q  R    +     S  R G  GG ++  K  
Sbjct: 118  LDNGIRFSSLNCEPFSKRCFS-------QLSRGKIGIEKIGVSDARSGSGGGKSWFNKHR 170

Query: 2096 QRFQK-QVKSSTAVRSSSFDEAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESK 2272
            +R      +  +   SSS   +                     K  + VS N ++N  SK
Sbjct: 171  KRNNAVSARGKSNATSSSISVSEDVNAVNSTSEQLVGDGVEGTKLGSSVS-NTKQN--SK 227

Query: 2273 PSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAKTKGSKQASRAK-KPIVTKAGQFSQSS 2449
            P      ++ S  +  +L      EQ S     K+    ++S+ K K       + +   
Sbjct: 228  PRARQQQQSRSKKKKEQLSATVASEQASVGKSCKSVSLAKSSKCKSKQCADLTSEKTSPG 287

Query: 2450 EILQ--VEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPVEVNKKPP 2623
              L+  +  + L  +QSKK  G+                    T +    VP   N +  
Sbjct: 288  NTLEQPLASSALTKQQSKKNSGNCGRKKKSAKATKASLQRQ--TSEEMVIVPRGQNTQ-- 343

Query: 2624 GRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRSGSVRPDDGF 2803
                 PLYPP GKSVVVVES+TKAKVIQGYLGDM+EVLPSYGHVRDLA RSGSVRPDD F
Sbjct: 344  ----NPLYPPSGKSVVVVESVTKAKVIQGYLGDMYEVLPSYGHVRDLAARSGSVRPDDDF 399

Query: 2804 SMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQDALHENINV 2983
            SMVWEVPSAAWTHLKSIKVAL+GAENLILASDPDREGEAIAWHI EMLQQQDALHENI V
Sbjct: 400  SMVWEVPSAAWTHLKSIKVALSGAENLILASDPDREGEAIAWHIVEMLQQQDALHENITV 459

Query: 2984 ARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWRKLPGCQSAG 3163
            ARVVFHEITE+SIK ALQAPR+I+ANLV AYLARR+LDYLIGF+ISPLLWRKLPGCQSAG
Sbjct: 460  ARVVFHEITEASIKVALQAPREIDANLVQAYLARRALDYLIGFNISPLLWRKLPGCQSAG 519

Query: 3164 RVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLTHFNFKKLEQ 3343
            RVQSAAL+LICDREM+IDEFKPQEYW+VE   ++KE   L+ +FSFP+HLTHF  K+L Q
Sbjct: 520  RVQSAALSLICDREMEIDEFKPQEYWTVEAVLDKKESHSLD-TFSFPAHLTHFQSKRLNQ 578

Query: 3344 LSISSQAEVKDIEEKITSSSF-VVVGSKMSKSRKNPLAPYITSTLQQDAANKFNFSASYT 3520
            LSISS  E KDIE+KI S++F V+  SK S  RKNP  PYITSTLQQDAANK NFSA+YT
Sbjct: 579  LSISSHTEAKDIEQKINSANFQVIKNSKRSMVRKNP-TPYITSTLQQDAANKLNFSATYT 637

Query: 3521 MKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            MK+AQKLYEGV+L D+ A GLITYMRTDGLH
Sbjct: 638  MKLAQKLYEGVQLPDETAAGLITYMRTDGLH 668


>ref|XP_007011466.1| DNA topoisomerase isoform 5 [Theobroma cacao]
            gi|508781829|gb|EOY29085.1| DNA topoisomerase isoform 5
            [Theobroma cacao]
          Length = 965

 Score =  530 bits (1366), Expect = e-147
 Identities = 306/579 (52%), Positives = 370/579 (63%), Gaps = 7/579 (1%)
 Frame = +2

Query: 1898 RNFTSRCLEISFRLDSPSYECFGRRFFSINAPQKSQFPRKSTNVNNNNASIRDGKSGGNN 2077
            RN  S C   +    S +      +FFS       QFPR +T   N++  +RDG+S G +
Sbjct: 129  RNIISTCASFNCIRSSSACVPLSIKFFS-------QFPRLATK--NDSMGVRDGRSSGFS 179

Query: 2078 Y-SFKRPQRFQKQVKSSTAVRSSSFDEAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVE 2254
            +  F R  +  K V +   ++ + F                              S +  
Sbjct: 180  FRGFNRHWKKPKGVAALNGIKGAPFRSPTSTSLLSNCKLDSTSTSLLNNANPGSTSTSPL 239

Query: 2255 KNAESKPSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAK----TKGSKQASRAKKPIVT 2422
             NA+ +  +S   K  S        +KK++E +S + V+       GSK AS       +
Sbjct: 240  TNAKPESKVSLQKKKQSR-------SKKNKEPISTTVVSDEAPVVNGSKTASPVGISNNS 292

Query: 2423 KAGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPV 2602
            K GQ    +   +   T  +P ++    GS+                  P K  + A   
Sbjct: 293  KNGQHHTPAS--EGNSTGNLPTEAHD--GSASTKLRSKKKSRSSSRKRQPMKAVNEAAQK 348

Query: 2603 EVNK--KPPGRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRS 2776
            +  +      R LK LYPP GKSV+VVES+TKAKVIQGYLGD FEVLPSYGHVRDLA RS
Sbjct: 349  QTPQHISQGQRPLKQLYPPTGKSVMVVESVTKAKVIQGYLGDTFEVLPSYGHVRDLAARS 408

Query: 2777 GSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQ 2956
            GSVRPDD FSMVWEVPSAAWTHLKSIKVAL+GAENL+LASDPDREGEAIAWHI EMLQQQ
Sbjct: 409  GSVRPDDDFSMVWEVPSAAWTHLKSIKVALSGAENLVLASDPDREGEAIAWHIFEMLQQQ 468

Query: 2957 DALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWR 3136
            DAL E +NVARVVFHEITE+SIKSALQ PR+I+ NLVHAYLARR+LDYLIGF+ISPLLWR
Sbjct: 469  DALGEKLNVARVVFHEITEASIKSALQVPREIDVNLVHAYLARRALDYLIGFNISPLLWR 528

Query: 3137 KLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLT 3316
            KLPGCQSAGRVQSAAL+LICDREM+IDEFKPQEYW++EV+   +E     K  SFP+HLT
Sbjct: 529  KLPGCQSAGRVQSAALSLICDREMEIDEFKPQEYWTIEVQLKIEESNVPVKDTSFPAHLT 588

Query: 3317 HFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDAANK 3496
            H+N KKL Q SISS    KDIE+KI   +  V+ SK +  R+NP  PYITSTLQQDAANK
Sbjct: 589  HYNSKKLGQFSISSDTGAKDIEQKINLENLRVISSKRNTMRRNPPTPYITSTLQQDAANK 648

Query: 3497 FNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
             NF A+YTMK+AQ+LYEG++LSD +A GLITY RTDGLH
Sbjct: 649  LNFPATYTMKLAQRLYEGIQLSDGKAAGLITYSRTDGLH 687


>ref|XP_007011465.1| DNA topoisomerase isoform 4 [Theobroma cacao]
            gi|508781828|gb|EOY29084.1| DNA topoisomerase isoform 4
            [Theobroma cacao]
          Length = 1069

 Score =  530 bits (1366), Expect = e-147
 Identities = 306/579 (52%), Positives = 370/579 (63%), Gaps = 7/579 (1%)
 Frame = +2

Query: 1898 RNFTSRCLEISFRLDSPSYECFGRRFFSINAPQKSQFPRKSTNVNNNNASIRDGKSGGNN 2077
            RN  S C   +    S +      +FFS       QFPR +T   N++  +RDG+S G +
Sbjct: 87   RNIISTCASFNCIRSSSACVPLSIKFFS-------QFPRLATK--NDSMGVRDGRSSGFS 137

Query: 2078 Y-SFKRPQRFQKQVKSSTAVRSSSFDEAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVE 2254
            +  F R  +  K V +   ++ + F                              S +  
Sbjct: 138  FRGFNRHWKKPKGVAALNGIKGAPFRSPTSTSLLSNCKLDSTSTSLLNNANPGSTSTSPL 197

Query: 2255 KNAESKPSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAK----TKGSKQASRAKKPIVT 2422
             NA+ +  +S   K  S        +KK++E +S + V+       GSK AS       +
Sbjct: 198  TNAKPESKVSLQKKKQSR-------SKKNKEPISTTVVSDEAPVVNGSKTASPVGISNNS 250

Query: 2423 KAGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPV 2602
            K GQ    +   +   T  +P ++    GS+                  P K  + A   
Sbjct: 251  KNGQHHTPAS--EGNSTGNLPTEAHD--GSASTKLRSKKKSRSSSRKRQPMKAVNEAAQK 306

Query: 2603 EVNK--KPPGRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRS 2776
            +  +      R LK LYPP GKSV+VVES+TKAKVIQGYLGD FEVLPSYGHVRDLA RS
Sbjct: 307  QTPQHISQGQRPLKQLYPPTGKSVMVVESVTKAKVIQGYLGDTFEVLPSYGHVRDLAARS 366

Query: 2777 GSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQ 2956
            GSVRPDD FSMVWEVPSAAWTHLKSIKVAL+GAENL+LASDPDREGEAIAWHI EMLQQQ
Sbjct: 367  GSVRPDDDFSMVWEVPSAAWTHLKSIKVALSGAENLVLASDPDREGEAIAWHIFEMLQQQ 426

Query: 2957 DALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWR 3136
            DAL E +NVARVVFHEITE+SIKSALQ PR+I+ NLVHAYLARR+LDYLIGF+ISPLLWR
Sbjct: 427  DALGEKLNVARVVFHEITEASIKSALQVPREIDVNLVHAYLARRALDYLIGFNISPLLWR 486

Query: 3137 KLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLT 3316
            KLPGCQSAGRVQSAAL+LICDREM+IDEFKPQEYW++EV+   +E     K  SFP+HLT
Sbjct: 487  KLPGCQSAGRVQSAALSLICDREMEIDEFKPQEYWTIEVQLKIEESNVPVKDTSFPAHLT 546

Query: 3317 HFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDAANK 3496
            H+N KKL Q SISS    KDIE+KI   +  V+ SK +  R+NP  PYITSTLQQDAANK
Sbjct: 547  HYNSKKLGQFSISSDTGAKDIEQKINLENLRVISSKRNTMRRNPPTPYITSTLQQDAANK 606

Query: 3497 FNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
             NF A+YTMK+AQ+LYEG++LSD +A GLITY RTDGLH
Sbjct: 607  LNFPATYTMKLAQRLYEGIQLSDGKAAGLITYSRTDGLH 645


>ref|XP_007011464.1| DNA topoisomerase isoform 3 [Theobroma cacao]
            gi|508781827|gb|EOY29083.1| DNA topoisomerase isoform 3
            [Theobroma cacao]
          Length = 1136

 Score =  530 bits (1366), Expect = e-147
 Identities = 306/579 (52%), Positives = 370/579 (63%), Gaps = 7/579 (1%)
 Frame = +2

Query: 1898 RNFTSRCLEISFRLDSPSYECFGRRFFSINAPQKSQFPRKSTNVNNNNASIRDGKSGGNN 2077
            RN  S C   +    S +      +FFS       QFPR +T   N++  +RDG+S G +
Sbjct: 87   RNIISTCASFNCIRSSSACVPLSIKFFS-------QFPRLATK--NDSMGVRDGRSSGFS 137

Query: 2078 Y-SFKRPQRFQKQVKSSTAVRSSSFDEAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVE 2254
            +  F R  +  K V +   ++ + F                              S +  
Sbjct: 138  FRGFNRHWKKPKGVAALNGIKGAPFRSPTSTSLLSNCKLDSTSTSLLNNANPGSTSTSPL 197

Query: 2255 KNAESKPSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAK----TKGSKQASRAKKPIVT 2422
             NA+ +  +S   K  S        +KK++E +S + V+       GSK AS       +
Sbjct: 198  TNAKPESKVSLQKKKQSR-------SKKNKEPISTTVVSDEAPVVNGSKTASPVGISNNS 250

Query: 2423 KAGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPV 2602
            K GQ    +   +   T  +P ++    GS+                  P K  + A   
Sbjct: 251  KNGQHHTPAS--EGNSTGNLPTEAHD--GSASTKLRSKKKSRSSSRKRQPMKAVNEAAQK 306

Query: 2603 EVNK--KPPGRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRS 2776
            +  +      R LK LYPP GKSV+VVES+TKAKVIQGYLGD FEVLPSYGHVRDLA RS
Sbjct: 307  QTPQHISQGQRPLKQLYPPTGKSVMVVESVTKAKVIQGYLGDTFEVLPSYGHVRDLAARS 366

Query: 2777 GSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQ 2956
            GSVRPDD FSMVWEVPSAAWTHLKSIKVAL+GAENL+LASDPDREGEAIAWHI EMLQQQ
Sbjct: 367  GSVRPDDDFSMVWEVPSAAWTHLKSIKVALSGAENLVLASDPDREGEAIAWHIFEMLQQQ 426

Query: 2957 DALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWR 3136
            DAL E +NVARVVFHEITE+SIKSALQ PR+I+ NLVHAYLARR+LDYLIGF+ISPLLWR
Sbjct: 427  DALGEKLNVARVVFHEITEASIKSALQVPREIDVNLVHAYLARRALDYLIGFNISPLLWR 486

Query: 3137 KLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLT 3316
            KLPGCQSAGRVQSAAL+LICDREM+IDEFKPQEYW++EV+   +E     K  SFP+HLT
Sbjct: 487  KLPGCQSAGRVQSAALSLICDREMEIDEFKPQEYWTIEVQLKIEESNVPVKDTSFPAHLT 546

Query: 3317 HFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDAANK 3496
            H+N KKL Q SISS    KDIE+KI   +  V+ SK +  R+NP  PYITSTLQQDAANK
Sbjct: 547  HYNSKKLGQFSISSDTGAKDIEQKINLENLRVISSKRNTMRRNPPTPYITSTLQQDAANK 606

Query: 3497 FNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
             NF A+YTMK+AQ+LYEG++LSD +A GLITY RTDGLH
Sbjct: 607  LNFPATYTMKLAQRLYEGIQLSDGKAAGLITYSRTDGLH 645


>ref|XP_007011463.1| DNA topoisomerase isoform 2 [Theobroma cacao]
            gi|508781826|gb|EOY29082.1| DNA topoisomerase isoform 2
            [Theobroma cacao]
          Length = 1087

 Score =  530 bits (1366), Expect = e-147
 Identities = 306/579 (52%), Positives = 370/579 (63%), Gaps = 7/579 (1%)
 Frame = +2

Query: 1898 RNFTSRCLEISFRLDSPSYECFGRRFFSINAPQKSQFPRKSTNVNNNNASIRDGKSGGNN 2077
            RN  S C   +    S +      +FFS       QFPR +T   N++  +RDG+S G +
Sbjct: 38   RNIISTCASFNCIRSSSACVPLSIKFFS-------QFPRLATK--NDSMGVRDGRSSGFS 88

Query: 2078 Y-SFKRPQRFQKQVKSSTAVRSSSFDEAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVE 2254
            +  F R  +  K V +   ++ + F                              S +  
Sbjct: 89   FRGFNRHWKKPKGVAALNGIKGAPFRSPTSTSLLSNCKLDSTSTSLLNNANPGSTSTSPL 148

Query: 2255 KNAESKPSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAK----TKGSKQASRAKKPIVT 2422
             NA+ +  +S   K  S        +KK++E +S + V+       GSK AS       +
Sbjct: 149  TNAKPESKVSLQKKKQSR-------SKKNKEPISTTVVSDEAPVVNGSKTASPVGISNNS 201

Query: 2423 KAGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHSAVPV 2602
            K GQ    +   +   T  +P ++    GS+                  P K  + A   
Sbjct: 202  KNGQHHTPAS--EGNSTGNLPTEAHD--GSASTKLRSKKKSRSSSRKRQPMKAVNEAAQK 257

Query: 2603 EVNK--KPPGRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRS 2776
            +  +      R LK LYPP GKSV+VVES+TKAKVIQGYLGD FEVLPSYGHVRDLA RS
Sbjct: 258  QTPQHISQGQRPLKQLYPPTGKSVMVVESVTKAKVIQGYLGDTFEVLPSYGHVRDLAARS 317

Query: 2777 GSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQ 2956
            GSVRPDD FSMVWEVPSAAWTHLKSIKVAL+GAENL+LASDPDREGEAIAWHI EMLQQQ
Sbjct: 318  GSVRPDDDFSMVWEVPSAAWTHLKSIKVALSGAENLVLASDPDREGEAIAWHIFEMLQQQ 377

Query: 2957 DALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWR 3136
            DAL E +NVARVVFHEITE+SIKSALQ PR+I+ NLVHAYLARR+LDYLIGF+ISPLLWR
Sbjct: 378  DALGEKLNVARVVFHEITEASIKSALQVPREIDVNLVHAYLARRALDYLIGFNISPLLWR 437

Query: 3137 KLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLT 3316
            KLPGCQSAGRVQSAAL+LICDREM+IDEFKPQEYW++EV+   +E     K  SFP+HLT
Sbjct: 438  KLPGCQSAGRVQSAALSLICDREMEIDEFKPQEYWTIEVQLKIEESNVPVKDTSFPAHLT 497

Query: 3317 HFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDAANK 3496
            H+N KKL Q SISS    KDIE+KI   +  V+ SK +  R+NP  PYITSTLQQDAANK
Sbjct: 498  HYNSKKLGQFSISSDTGAKDIEQKINLENLRVISSKRNTMRRNPPTPYITSTLQQDAANK 557

Query: 3497 FNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
             NF A+YTMK+AQ+LYEG++LSD +A GLITY RTDGLH
Sbjct: 558  LNFPATYTMKLAQRLYEGIQLSDGKAAGLITYSRTDGLH 596


>ref|XP_004136444.1| PREDICTED: DNA topoisomerase 1-like [Cucumis sativus]
          Length = 1163

 Score =  529 bits (1362), Expect = e-147
 Identities = 313/682 (45%), Positives = 408/682 (59%), Gaps = 14/682 (2%)
 Frame = +2

Query: 1610 HLPNMLQCRTLEKYPGTFLPYSPFLSVGKYGKCTQLAFRKKGETGRLTKDKLIGLRFKVE 1789
            H    LQ  TL+ Y   + P  PF +     +C+QL FRK G T  +T ++         
Sbjct: 37   HFTTKLQGSTLQNYTSKYTPVLPFSTACNSARCSQLVFRKGGVTFAVTTERT-------- 88

Query: 1790 RDTRPFKSCNGEHRQSQSVTFQTQLQFGFPCTMKYVRNFTSRCLEISFRLDSPSYECFGR 1969
                 +++C+G        T  ++L   FP +         + L   F    P+Y  FGR
Sbjct: 89   -KAGQYRACDGP----SVFTLYSRLPLRFPHSAALPNASNQQLLNGIFAHKLPNYRAFGR 143

Query: 1970 RFFS-----INAPQKS--QFPRKSTN---VNNNNASIRDGKSGGNNYSFKRPQRFQKQVK 2119
            +FFS     +N  +K   ++ RK T+   +  +N  ++  K    +         +K++ 
Sbjct: 144  KFFSNTTEALNGTKKKNVKYARKGTSTFPIEGSNKKLKGEKPVATSR--------KKRIS 195

Query: 2120 SSTAVRSSSFDEAHXXXXXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESKPSISTPAKN 2299
            +S A  S+   E +                      +  V    E N  S  S +  A  
Sbjct: 196  ASKASGSTYVGETN--------------------SSDQLVGAMKEANLVSSSSSTRKASK 235

Query: 2300 NSNDQVTKLGNKKHEEQLSGSGVAKTKGSKQASRAKKPIVTKAGQFSQSSEILQVEETTL 2479
              N++ ++  +KK +E +S +  A  K   +  ++K       G  +   +++Q  +  +
Sbjct: 236  GLNEKKSR--SKKKKEAISSTNDADVKAVCKDGQSKS-----FGSSNTDQDVVQDPKKNV 288

Query: 2480 IPEQSKKTVG----SSXXXXXXXXXXXXXXSDNVPTKKHHSAVPVEVNKKPPGRKLKPLY 2647
                SK +      S+              S N   +K H  V      +      K LY
Sbjct: 289  TGGTSKDSASTKKKSNKQKRSSSRKKEATKSANKLRQKPHVVVDARGTSQVR-TTFKQLY 347

Query: 2648 PPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRSGSVRPDDGFSMVWEVPS 2827
            PP GKSVV+VES+ KAKVIQ YLGDMF VLPS+GHVRDLA RSGSVRPDD F MVWEVPS
Sbjct: 348  PPMGKSVVIVESVAKAKVIQNYLGDMFVVLPSHGHVRDLAARSGSVRPDDDFIMVWEVPS 407

Query: 2828 AAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQDALHENINVARVVFHEI 3007
            AAWTHLKSI+++LNGAENLILASDPDREGEAIAWHI EMLQ Q++LHE I++ARVVFHEI
Sbjct: 408  AAWTHLKSIELSLNGAENLILASDPDREGEAIAWHIIEMLQHQNSLHEGISIARVVFHEI 467

Query: 3008 TESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWRKLPGCQSAGRVQSAALA 3187
            TE+SIKSALQ+PR I+ NLV AYLARR+LDYLIGF+ISPLLWRKLPGC+SAGRVQSAALA
Sbjct: 468  TEASIKSALQSPRVIDENLVQAYLARRALDYLIGFNISPLLWRKLPGCRSAGRVQSAALA 527

Query: 3188 LICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLTHFNFKKLEQLSISSQAE 3367
            LICDREM+IDEF  QEYW+++++ N+K P      F+ P+HLTHF+FKKL QL+ISS  E
Sbjct: 528  LICDREMEIDEFHAQEYWTIDIKLNQKNPCSSVGDFAVPAHLTHFDFKKLNQLAISSNME 587

Query: 3368 VKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDAANKFNFSASYTMKVAQKLYE 3547
             K+IE  + S +F V+ SK S  + NP  PYITSTLQQDAANKFNF ASYTM++AQKLYE
Sbjct: 588  AKNIETALKSVNFQVLSSKKSIVQTNPPMPYITSTLQQDAANKFNFPASYTMQLAQKLYE 647

Query: 3548 GVKLSDDEATGLITYMRTDGLH 3613
            G++L+D +A GLITY RTDGLH
Sbjct: 648  GIQLADGKAAGLITYPRTDGLH 669


>ref|XP_006450082.1| hypothetical protein CICLE_v10007345mg [Citrus clementina]
            gi|557553308|gb|ESR63322.1| hypothetical protein
            CICLE_v10007345mg [Citrus clementina]
          Length = 984

 Score =  528 bits (1361), Expect = e-147
 Identities = 294/465 (63%), Positives = 336/465 (72%), Gaps = 1/465 (0%)
 Frame = +2

Query: 2222 KPNAQVSGNVEKNAESKPSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAKTKGSKQASR 2401
            K N  VS   + NA ++ SIS     N+ +  +        EQL G GV   K     S 
Sbjct: 56   KRNNAVSARGKSNA-TRSSISASEDVNAVNSTS--------EQLVGDGVEGAKLGSSVSN 106

Query: 2402 AKKPIVTKAGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKK 2581
             K+    +A Q  QS    + E+ +      + +VG S                   + K
Sbjct: 107  TKQNSKPRARQQQQSRSKKKKEQLSATVASEQASVGKSCKSV-----------SQAKSSK 155

Query: 2582 HHSAVPVEVNKKPPGRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRD 2761
              S    ++  +       PLYPP GKSVVVVES+TKAKVIQGYLGDM+EVLPSYGHVRD
Sbjct: 156  CKSEQCADLTSE------NPLYPPSGKSVVVVESVTKAKVIQGYLGDMYEVLPSYGHVRD 209

Query: 2762 LAGRSGSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITE 2941
            LA RSGSVRPDD FSMVWEVPSAAWTHLKSIKVAL+GAENLILASDPDREGEAIAWHI E
Sbjct: 210  LAARSGSVRPDDDFSMVWEVPSAAWTHLKSIKVALSGAENLILASDPDREGEAIAWHIVE 269

Query: 2942 MLQQQDALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSIS 3121
            MLQQQDALHENI VARVVFHEITE+SIK ALQA R+I+ANLV AYLARR+LDYLIGF+IS
Sbjct: 270  MLQQQDALHENITVARVVFHEITEASIKVALQAAREIDANLVQAYLARRALDYLIGFNIS 329

Query: 3122 PLLWRKLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSF 3301
            PLLWRKLPGCQSAGRVQSAAL+LICDREM+IDEFKPQEYW+VE   ++KE   L+ +FSF
Sbjct: 330  PLLWRKLPGCQSAGRVQSAALSLICDREMEIDEFKPQEYWTVEAVLDKKESHSLD-TFSF 388

Query: 3302 PSHLTHFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGS-KMSKSRKNPLAPYITSTLQ 3478
            P+HLTHF  K+L QLSI S  E KDIE+KI S++F V+ + K S  RKNP  PYITSTLQ
Sbjct: 389  PAHLTHFQSKRLNQLSIGSHTEAKDIEQKINSANFQVIKNYKRSMVRKNP-TPYITSTLQ 447

Query: 3479 QDAANKFNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            QDAANK NFSA+YTMK+AQKLYEGV+L D  A GLITYMRTDGLH
Sbjct: 448  QDAANKLNFSATYTMKLAQKLYEGVQLPDGTAAGLITYMRTDGLH 492


>ref|XP_007225278.1| hypothetical protein PRUPE_ppa001428mg [Prunus persica]
            gi|462422214|gb|EMJ26477.1| hypothetical protein
            PRUPE_ppa001428mg [Prunus persica]
          Length = 831

 Score =  525 bits (1353), Expect = e-146
 Identities = 264/334 (79%), Positives = 292/334 (87%), Gaps = 1/334 (0%)
 Frame = +2

Query: 2615 KPPGRK-LKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAGRSGSVRP 2791
            KP G+  LK LYP  G++VVVVES TKAKVIQGYLGDMFEVLPSYGHVRDLA RSGSVRP
Sbjct: 5    KPQGKMTLKQLYPATGRTVVVVESATKAKVIQGYLGDMFEVLPSYGHVRDLAARSGSVRP 64

Query: 2792 DDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQQQDALHE 2971
            DD FSMVWEVPSAAWTHLKSIKVAL GAENLILASDPDREGEAIAWHI EMLQQQDAL E
Sbjct: 65   DDDFSMVWEVPSAAWTHLKSIKVALTGAENLILASDPDREGEAIAWHIIEMLQQQDALRE 124

Query: 2972 NINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLLWRKLPGC 3151
            +INVARVVFHEITE+SIKSALQAPR+I+ NLVHAYLARR+LDYLIGF+ISPLLWRKLPGC
Sbjct: 125  DINVARVVFHEITETSIKSALQAPREIDENLVHAYLARRALDYLIGFNISPLLWRKLPGC 184

Query: 3152 QSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSHLTHFNFK 3331
            QSAGRVQSAALAL+CDREM+IDEFK QEYW+ E+E N+KEP     +  F +HLTHF+ K
Sbjct: 185  QSAGRVQSAALALLCDREMEIDEFKQQEYWTAEIELNQKEPGSSVNAPDFSAHLTHFDSK 244

Query: 3332 KLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDAANKFNFSA 3511
            KL Q SI S  + K+IE++I S +F VV SK +K RKNP  PYITSTLQQDAANK +FSA
Sbjct: 245  KLNQFSIDSHTKAKEIEQQINSQNFQVVSSKKNKMRKNPPTPYITSTLQQDAANKLHFSA 304

Query: 3512 SYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            +YTMK+AQKLYEGV+LSD +A GLITYMRTDGLH
Sbjct: 305  AYTMKLAQKLYEGVQLSDGKAAGLITYMRTDGLH 338


>ref|XP_002528003.1| prokaryotic DNA topoisomerase, putative [Ricinus communis]
            gi|223532629|gb|EEF34415.1| prokaryotic DNA
            topoisomerase, putative [Ricinus communis]
          Length = 1071

 Score =  525 bits (1352), Expect = e-146
 Identities = 286/463 (61%), Positives = 337/463 (72%)
 Frame = +2

Query: 2225 PNAQVSGNVEKNAESKPSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAKTKGSKQASRA 2404
            P  Q SG+V  N +S   ++TP   NS    T   +KKH +  S    + T   ++A++A
Sbjct: 160  PTEQSSGDV--NLDSTAPVTTP---NSKPTPTTTRHKKHSKTNSKKQQSSTS-VEEAAQA 213

Query: 2405 KKPIVTKAGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKH 2584
            K    TK    ++  E+L    +T  P+ +KKT                  +  V   K 
Sbjct: 214  KTSSSTKTK--TKPKELLDASASTK-PQPNKKT-------RKPTGKPKAIKTVKVSPDKQ 263

Query: 2585 HSAVPVEVNKKPPGRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDL 2764
                P+  +K      LKPLYPP  KSVVVVES+TKAKVIQGYLG MFEVLPSYGHVRDL
Sbjct: 264  QQHKPMHKSKPFRQGSLKPLYPPTAKSVVVVESVTKAKVIQGYLGPMFEVLPSYGHVRDL 323

Query: 2765 AGRSGSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEM 2944
            A RSGSVRPDD FSMVWEVPS AWTHLK+IKVALNGAENL+LASDPDREGEAIAWHI EM
Sbjct: 324  AARSGSVRPDDDFSMVWEVPSPAWTHLKTIKVALNGAENLVLASDPDREGEAIAWHIIEM 383

Query: 2945 LQQQDALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISP 3124
            LQQQDALH+ + VARVVFHEITE SIK+ALQAPR+I+ NLVHAYLARR+LDYLIGF+ISP
Sbjct: 384  LQQQDALHQGVTVARVVFHEITEQSIKNALQAPREIDLNLVHAYLARRALDYLIGFNISP 443

Query: 3125 LLWRKLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFP 3304
            LLWRKLPGCQSAGRVQSAAL+LICDREM+IDEF PQEYW+++VE        +E   S  
Sbjct: 444  LLWRKLPGCQSAGRVQSAALSLICDREMEIDEFTPQEYWTIDVEL-----YIMETGSSVN 498

Query: 3305 SHLTHFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQD 3484
            + LTHF+F KL QLS+ S  E +DIE+KI  +SF+V G+K SK R+NP  PYITSTLQQD
Sbjct: 499  ARLTHFDFNKLNQLSVRSHTEARDIEQKINVASFLVAGAKESKMRRNPPTPYITSTLQQD 558

Query: 3485 AANKFNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            AANK +FS+ YTMK+AQKLYEGV+LSD + TGLITY+RTDGLH
Sbjct: 559  AANKLHFSSMYTMKLAQKLYEGVQLSDGKTTGLITYIRTDGLH 601


>ref|XP_004233765.1| PREDICTED: DNA topoisomerase 1-like [Solanum lycopersicum]
          Length = 1173

 Score =  525 bits (1351), Expect = e-146
 Identities = 332/705 (47%), Positives = 412/705 (58%), Gaps = 45/705 (6%)
 Frame = +2

Query: 1634 RTLEKYPGTFLPYSPFLSVGKYGKCTQLAFRKKGETGRLTKDKLIGLRFKVERDTRPFKS 1813
            RTL  Y    L  S F +V  + K ++ A    G   R  ++    LR   ++   P +S
Sbjct: 21   RTLHNYQANCLQCSTFATVDSFEKMSRKARICCGIRARQPRN----LRVVSQQKIHPLRS 76

Query: 1814 CNGEHRQSQSVTFQTQL-QFGFPCTMKYVRNFTSRCLEISFRLDSPSYECFGRRFFSINA 1990
                   S S     QL + GFP T   +          SFR     +   G R  S N 
Sbjct: 77   YYTNEPGSSSAFSVLQLSKEGFPSTPMPII--------FSFR----PFGGIGSR--SYNT 122

Query: 1991 PQKSQFPRKSTNVNNNNASIRDGKSGGNNYSFKRPQRFQKQVKSSTAVRSSSFDEAHXXX 2170
              K  F R +  + +  +      S GN   FK  +   ++       R ++  +     
Sbjct: 123  DGKMHFSRDARAIADKGSGGAKVFSDGNKTFFKNLKNHSERSNELAVHRRNALSDKVTEK 182

Query: 2171 XXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESKPSISTPAKNNSND------------- 2311
                              PN++VS +  KN +   S  TP K +  D             
Sbjct: 183  GT----------------PNSKVSAS--KNVDLVISKDTPVKTDEKDVNLDISGIPLGNN 224

Query: 2312 ---------QVTKLGNKKHEEQLSGSGVAKTKGSKQASRAKKPIVTK------------- 2425
                     +  K    K ++ +S + V + K SK   RAKKP   K             
Sbjct: 225  GKPTSTGSEKTKKQSRSKKDKNVSSATVDQPKASK-TRRAKKPSPAKDEESPAVSEISSP 283

Query: 2426 --------AGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKK 2581
                    A   S   ++ QV+ T+  P + K T  S+              S  V  K 
Sbjct: 284  VHSSSVGPADNVSMKVDLAQVKRTS--PRKRKPTKVSNSVAELNGATVVPSDSKLVTDKS 341

Query: 2582 HHSAVPVEVNKKPPGRKLKP-LYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVR 2758
                  V    KPPG+K  P LYPP  KSV+VVES+TKA+VIQGYLGDMFEVLPSYGHVR
Sbjct: 342  SD----VSSKSKPPGQKKWPKLYPPTAKSVLVVESVTKARVIQGYLGDMFEVLPSYGHVR 397

Query: 2759 DLAGRSGSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHIT 2938
            DLA RSGSVRPDD FSMVWEVPSAAWTHLKSIKVAL+GA+NLILASDPDREGEAI+WHI 
Sbjct: 398  DLAARSGSVRPDDDFSMVWEVPSAAWTHLKSIKVALSGAQNLILASDPDREGEAISWHII 457

Query: 2939 EMLQQQDALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSI 3118
            EMLQQQDAL ++INV RVVF+EITESSIK++LQ+PR+I+ANLVHAYLARR+LDYLIGF+I
Sbjct: 458  EMLQQQDALRDDINVTRVVFNEITESSIKASLQSPREIDANLVHAYLARRALDYLIGFNI 517

Query: 3119 SPLLWRKLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFS 3298
            SPLLWRKLPGCQSAGRVQSAAL+LICDREM+ID FKPQEYW+V VEF + +   L  +F 
Sbjct: 518  SPLLWRKLPGCQSAGRVQSAALSLICDREMEIDGFKPQEYWTVLVEFKKNKNLDLANNF- 576

Query: 3299 FPSHLTHFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQ 3478
              SHLTHF+ KKL Q S+SS  E  +IE KI SS+F V+ SK++K ++NP  PYITSTLQ
Sbjct: 577  LSSHLTHFDTKKLSQFSVSSHTEAMEIEGKINSSNFEVLSSKITKKQRNPSPPYITSTLQ 636

Query: 3479 QDAANKFNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            QDAANK +FS++YTMK+AQKLYEG++LSD ++TGLITY+RTDGLH
Sbjct: 637  QDAANKLDFSSTYTMKLAQKLYEGIQLSDGKSTGLITYIRTDGLH 681


>ref|XP_007011462.1| DNA topoisomerase isoform 1 [Theobroma cacao]
            gi|508781825|gb|EOY29081.1| DNA topoisomerase isoform 1
            [Theobroma cacao]
          Length = 1011

 Score =  519 bits (1336), Expect = e-144
 Identities = 292/529 (55%), Positives = 350/529 (66%), Gaps = 7/529 (1%)
 Frame = +2

Query: 2048 IRDGKSGGNNY-SFKRPQRFQKQVKSSTAVRSSSFDEAHXXXXXXXXXXXXXXXXXXXMK 2224
            +RDG+S G ++  F R  +  K V +   ++ + F                         
Sbjct: 3    VRDGRSSGFSFRGFNRHWKKPKGVAALNGIKGAPFRSPTSTSLLSNCKLDSTSTSLLNNA 62

Query: 2225 PNAQVSGNVEKNAESKPSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAK----TKGSKQ 2392
                 S +   NA+ +  +S   K  S        +KK++E +S + V+       GSK 
Sbjct: 63   NPGSTSTSPLTNAKPESKVSLQKKKQSR-------SKKNKEPISTTVVSDEAPVVNGSKT 115

Query: 2393 ASRAKKPIVTKAGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVP 2572
            AS       +K GQ    +   +   T  +P ++    GS+                  P
Sbjct: 116  ASPVGISNNSKNGQHHTPAS--EGNSTGNLPTEAHD--GSASTKLRSKKKSRSSSRKRQP 171

Query: 2573 TKKHHSAVPVEVNK--KPPGRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSY 2746
             K  + A   +  +      R LK LYPP GKSV+VVES+TKAKVIQGYLGD FEVLPSY
Sbjct: 172  MKAVNEAAQKQTPQHISQGQRPLKQLYPPTGKSVMVVESVTKAKVIQGYLGDTFEVLPSY 231

Query: 2747 GHVRDLAGRSGSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIA 2926
            GHVRDLA RSGSVRPDD FSMVWEVPSAAWTHLKSIKVAL+GAENL+LASDPDREGEAIA
Sbjct: 232  GHVRDLAARSGSVRPDDDFSMVWEVPSAAWTHLKSIKVALSGAENLVLASDPDREGEAIA 291

Query: 2927 WHITEMLQQQDALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLI 3106
            WHI EMLQQQDAL E +NVARVVFHEITE+SIKSALQ PR+I+ NLVHAYLARR+LDYLI
Sbjct: 292  WHIFEMLQQQDALGEKLNVARVVFHEITEASIKSALQVPREIDVNLVHAYLARRALDYLI 351

Query: 3107 GFSISPLLWRKLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLE 3286
            GF+ISPLLWRKLPGCQSAGRVQSAAL+LICDREM+IDEFKPQEYW++EV+   +E     
Sbjct: 352  GFNISPLLWRKLPGCQSAGRVQSAALSLICDREMEIDEFKPQEYWTIEVQLKIEESNVPV 411

Query: 3287 KSFSFPSHLTHFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYIT 3466
            K  SFP+HLTH+N KKL Q SISS    KDIE+KI   +  V+ SK +  R+NP  PYIT
Sbjct: 412  KDTSFPAHLTHYNSKKLGQFSISSDTGAKDIEQKINLENLRVISSKRNTMRRNPPTPYIT 471

Query: 3467 STLQQDAANKFNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            STLQQDAANK NF A+YTMK+AQ+LYEG++LSD +A GLITY RTDGLH
Sbjct: 472  STLQQDAANKLNFPATYTMKLAQRLYEGIQLSDGKAAGLITYSRTDGLH 520


>ref|XP_007158787.1| hypothetical protein PHAVU_002G181900g [Phaseolus vulgaris]
            gi|561032202|gb|ESW30781.1| hypothetical protein
            PHAVU_002G181900g [Phaseolus vulgaris]
          Length = 1057

 Score =  515 bits (1326), Expect = e-143
 Identities = 274/421 (65%), Positives = 322/421 (76%), Gaps = 6/421 (1%)
 Frame = +2

Query: 2369 AKTKGSKQASRAKKPIVTKAGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXX 2548
            AKT  +K   + KKP   K  + S +S+    E    +PE+S K+               
Sbjct: 148  AKTAENKTVKK-KKPSPRK--KVSAASKSTHEECVAAVPEKSTKSKRKKVSKKSSVDSAT 204

Query: 2549 XXXSDNVPT------KKHHSAVPVEVNKKPPGRKLKPLYPPRGKSVVVVESLTKAKVIQG 2710
               +DN  +      KK+  +  +E  K       KPLYPP GKSVVVVES+TKAKVI+G
Sbjct: 205  EEIADNSASVKDELKKKNGKSSVIEEAKPLWNFTHKPLYPPSGKSVVVVESVTKAKVIKG 264

Query: 2711 YLGDMFEVLPSYGHVRDLAGRSGSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLIL 2890
            YLGDM+EVLPSYGHVRDLA RSGSVRPD+ FSMVWEVPS AWTHLKSIKVAL+GAENLIL
Sbjct: 265  YLGDMYEVLPSYGHVRDLAARSGSVRPDEDFSMVWEVPSPAWTHLKSIKVALSGAENLIL 324

Query: 2891 ASDPDREGEAIAWHITEMLQQQDALHENINVARVVFHEITESSIKSALQAPRDINANLVH 3070
            ASDPDREGEAI+WHI EMLQQQ ALH+NI++ARVVFHEITE SIK ALQ PR+I+ NLV 
Sbjct: 325  ASDPDREGEAISWHIIEMLQQQGALHDNISLARVVFHEITEKSIKVALQTPREIDINLVQ 384

Query: 3071 AYLARRSLDYLIGFSISPLLWRKLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVE 3250
            AYLARR+LDYLIGF+ISPLLWRKLPGCQSAGRVQSAALALICDREM+IDEFKP+EYW+VE
Sbjct: 385  AYLARRALDYLIGFNISPLLWRKLPGCQSAGRVQSAALALICDREMEIDEFKPKEYWTVE 444

Query: 3251 VEFNRKEPERLEKSFSFPSHLTHFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMS 3430
            V+  +K+P    ++F+FPSHLTHF+ KKL Q SI+S AE + I+  I S+ F VV  K S
Sbjct: 445  VQLKKKDPGS-NQNFTFPSHLTHFDSKKLNQFSITSDAEARYIQSNINSADFHVVCLKKS 503

Query: 3431 KSRKNPLAPYITSTLQQDAANKFNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGL 3610
            K+R+NP  PYITSTLQQDAANK +F+AS+TMK+AQKLYEGV+LSD  A GLITY+RTDG 
Sbjct: 504  KTRRNPPTPYITSTLQQDAANKLHFTASHTMKLAQKLYEGVELSDGVAVGLITYIRTDGF 563

Query: 3611 H 3613
            H
Sbjct: 564  H 564


>ref|XP_006382211.1| hypothetical protein POPTR_0006s29400g [Populus trichocarpa]
            gi|550337366|gb|ERP60008.1| hypothetical protein
            POPTR_0006s29400g [Populus trichocarpa]
          Length = 1120

 Score =  513 bits (1322), Expect = e-142
 Identities = 316/669 (47%), Positives = 402/669 (60%), Gaps = 6/669 (0%)
 Frame = +2

Query: 1625 LQCRTLEKYPGTFLPYSPFLSVGKYGKCTQLAFRKKGETGRLTKDKLIGLRFKVERDTRP 1804
            LQCRT + YP + LP     +   Y +C+Q+         +L KD+L    F +  +   
Sbjct: 28   LQCRTFQNYPASHLPIGT--TCRNYMQCSQI---------KLKKDRL---SFIISINHSQ 73

Query: 1805 FKSCNGEHRQSQSVTFQTQLQFGFPCTMKYVRNFTSRCLEISFRLDSPSYECFGRRFFSI 1984
              +  G    S ++          P ++    +F +        L S     F +R FS 
Sbjct: 74   SLTNGGSMSMSSAINSHLS-----PGSLLNYWSFNN-----GNTLTSLESGVFAKRLFST 123

Query: 1985 NAPQKSQFPRKSTNVNNNNASIRDGKSGGNNYSFKRPQRFQKQVKSSTAVRSSSFDEAHX 2164
                       S   NN N ++     GG +  +K+P       K+S A      DE + 
Sbjct: 124  ----------ASRGSNNKNQNV-----GGFSKHWKKP-------KASGAAHDK--DETNT 159

Query: 2165 XXXXXXXXXXXXXXXXXXMKPNAQVSGNVEKNAESKPSISTPAKNNSNDQVTKLGNKKHE 2344
                                 +A++   V +    K  ++   K  S        +KK++
Sbjct: 160  NSRISASKDVDAVTSTETAVGDAKLGSAVSRTRNKKSKVNETEKKESK-------SKKNK 212

Query: 2345 EQLSGSGVA-KTKGSKQ---ASRAKKPIVTKAGQFSQSSEILQVEETTLIPEQSKKTVGS 2512
             + S + V+ K  G+K     S+ KK + +K+GQ +  +   Q + T  +P  S K   +
Sbjct: 213  GEASFTAVSEKAAGAKSMTTTSQLKKSLPSKSGQVAARAS--QKKATEEMPNGSTKQQSN 270

Query: 2513 SXXXXXXXXXXXXXXSDNVPTKKHHSAVPVEVNKKPPGR--KLKPLYPPRGKSVVVVESL 2686
                            +    K+     P ++ K  P    KLK LYP  GK VVVVES+
Sbjct: 271  KKNGNSSIKRTTKKAVNGSAEKQK----PQKIGKLQPFAQGKLKSLYPSAGKCVVVVESV 326

Query: 2687 TKAKVIQGYLGDMFEVLPSYGHVRDLAGRSGSVRPDDGFSMVWEVPSAAWTHLKSIKVAL 2866
            TKAKVIQGYLGDM+EVLPSYGHVRDLA RSGSVRPDD FS+VWEVPSAAWTHL SIKVAL
Sbjct: 327  TKAKVIQGYLGDMYEVLPSYGHVRDLAARSGSVRPDDDFSIVWEVPSAAWTHLNSIKVAL 386

Query: 2867 NGAENLILASDPDREGEAIAWHITEMLQQQDALHENINVARVVFHEITESSIKSALQAPR 3046
            +GA+ LILASDPDREGEAIAWHI EMLQQQDAL +++ VARVVFHEITE+SIK+ALQAPR
Sbjct: 387  SGAKILILASDPDREGEAIAWHIVEMLQQQDALRQDLTVARVVFHEITETSIKNALQAPR 446

Query: 3047 DINANLVHAYLARRSLDYLIGFSISPLLWRKLPGCQSAGRVQSAALALICDREMDIDEFK 3226
             I+ NLVHAYLARR+LDYLIGF+ISPLLWRKLPGCQSAGRVQSAAL+L+CDREM+IDEF 
Sbjct: 447  GIDVNLVHAYLARRALDYLIGFNISPLLWRKLPGCQSAGRVQSAALSLLCDREMEIDEFN 506

Query: 3227 PQEYWSVEVEFNRKEPERLEKSFSFPSHLTHFNFKKLEQLSISSQAEVKDIEEKITSSSF 3406
             QEYW++  +  ++E + L       +HLTHF+ KKL Q SISS  E KD+E+KI S+ F
Sbjct: 507  SQEYWTIGAKLKKQEQDSLVN-----AHLTHFDSKKLNQFSISSDTEAKDMEQKINSADF 561

Query: 3407 VVVGSKMSKSRKNPLAPYITSTLQQDAANKFNFSASYTMKVAQKLYEGVKLSDDEATGLI 3586
             VVGSK +K+ +NP  PYITSTLQQDAANK +F+ SYTMKVAQKLYEGV+LSD +ATGLI
Sbjct: 562  QVVGSKKTKTHRNPPTPYITSTLQQDAANKLDFATSYTMKVAQKLYEGVQLSDGKATGLI 621

Query: 3587 TYMRTDGLH 3613
            TY+RTDGLH
Sbjct: 622  TYLRTDGLH 630


>ref|XP_006601080.1| PREDICTED: DNA topoisomerase 3-alpha-like isoform X6 [Glycine max]
          Length = 879

 Score =  513 bits (1321), Expect = e-142
 Identities = 277/461 (60%), Positives = 327/461 (70%), Gaps = 1/461 (0%)
 Frame = +2

Query: 2234 QVSGNVEKNAESKPSISTPAKNNSNDQVTKLGNKKHEEQLSGSGVAKTKGSK-QASRAKK 2410
            QV   V +  E        A +   D          E++  GS  A   G + + S  KK
Sbjct: 118  QVRAAVVRGKEKDGGAVNDAASKEVDNAAASEGSLGEKKKKGSSRAAASGEEDEKSVKKK 177

Query: 2411 PIVTKAGQFSQSSEILQVEETTLIPEQSKKTVGSSXXXXXXXXXXXXXXSDNVPTKKHHS 2590
                K    +Q    ++  + +    + K +  S               + +   KK+ +
Sbjct: 178  TAKQKKTTSTQEDGAVEASKKSSKGNKKKDSKKSLTESAIEEITENSASAKDKVKKKNGN 237

Query: 2591 AVPVEVNKKPPGRKLKPLYPPRGKSVVVVESLTKAKVIQGYLGDMFEVLPSYGHVRDLAG 2770
            +  +E  K       KPLYPP GKSVVVVES+TKAKVI+ YLGDM+EVLPSYGHVRDLA 
Sbjct: 238  SSLIEEAKPLWNFTYKPLYPPTGKSVVVVESVTKAKVIKRYLGDMYEVLPSYGHVRDLAA 297

Query: 2771 RSGSVRPDDGFSMVWEVPSAAWTHLKSIKVALNGAENLILASDPDREGEAIAWHITEMLQ 2950
            RSGSVRPDD FSMVWEVPS AWTHLKSIKVAL+GAENLILASDPDREGEAIAWHI EMLQ
Sbjct: 298  RSGSVRPDDDFSMVWEVPSPAWTHLKSIKVALSGAENLILASDPDREGEAIAWHIIEMLQ 357

Query: 2951 QQDALHENINVARVVFHEITESSIKSALQAPRDINANLVHAYLARRSLDYLIGFSISPLL 3130
            QQ ALH+NI++ARVVFHEITE SIK +LQ PR+I+ NLV AYLARR+LDYLIGFSISPLL
Sbjct: 358  QQGALHDNISLARVVFHEITEKSIKGSLQTPREIDINLVQAYLARRALDYLIGFSISPLL 417

Query: 3131 WRKLPGCQSAGRVQSAALALICDREMDIDEFKPQEYWSVEVEFNRKEPERLEKSFSFPSH 3310
            WRKLPGCQSAGRVQSAAL+LICDREM+IDEFKP+EYW VEV+  +KE  R  K+ +FP+H
Sbjct: 418  WRKLPGCQSAGRVQSAALSLICDREMEIDEFKPKEYWIVEVQLKKKE-LRSNKNLTFPAH 476

Query: 3311 LTHFNFKKLEQLSISSQAEVKDIEEKITSSSFVVVGSKMSKSRKNPLAPYITSTLQQDAA 3490
            LTHF+ KKL Q SI+S  E +DI+  I S+ F VV  K SKSR+NP  PYITSTLQQDAA
Sbjct: 477  LTHFDSKKLNQFSITSDTEARDIQSTINSADFHVVSLKKSKSRRNPPTPYITSTLQQDAA 536

Query: 3491 NKFNFSASYTMKVAQKLYEGVKLSDDEATGLITYMRTDGLH 3613
            NK +F+AS+TMK+AQKLYEGV+LSD  A GLITY+RTDGLH
Sbjct: 537  NKLHFTASHTMKLAQKLYEGVELSDGIAVGLITYIRTDGLH 577