BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Akebia23_contig00013119
         (2830 letters)

Database: ./nr 
           38,876,450 sequences; 13,856,398,315 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis v...  1203   0.0  
emb|CBI24922.3| unnamed protein product [Vitis vinifera]             1147   0.0  
ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cac...  1107   0.0  
ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cac...  1104   0.0  
ref|XP_006439079.1| hypothetical protein CICLE_v10030505mg [Citr...  1085   0.0  
ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2-like [Citrus ...  1084   0.0  
gb|EXB68160.1| DNA topoisomerase 2 [Morus notabilis]                 1080   0.0  
ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum...  1079   0.0  
ref|XP_006439078.1| hypothetical protein CICLE_v10030505mg [Citr...  1079   0.0  
ref|XP_002298421.2| DNA topoisomerase family protein [Populus tr...  1077   0.0  
ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2-like [Solanum...  1073   0.0  
gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984...  1067   0.0  
ref|XP_007220582.1| hypothetical protein PRUPE_ppa000202mg [Prun...  1053   0.0  
ref|XP_002314046.2| DNA topoisomerase family protein [Populus tr...  1048   0.0  
ref|XP_004308680.1| PREDICTED: DNA topoisomerase 2-like [Fragari...  1043   0.0  
ref|XP_006838283.1| hypothetical protein AMTR_s00103p00101630 [A...  1025   0.0  
ref|XP_004149716.1| PREDICTED: DNA topoisomerase 2-like [Cucumis...  1010   0.0  
ref|XP_004165384.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisom...  1009   0.0  
ref|XP_007009329.1| Topoisomerase II isoform 3 [Theobroma cacao]...  1007   0.0  
emb|CAJ44361.1| putative DNA topoisomerase II [Malus domestica]      1004   0.0  

>ref|XP_002274267.1| PREDICTED: DNA topoisomerase 2-like [Vitis vinifera]
          Length = 1489

 Score = 1203 bits (3112), Expect = 0.0
 Identities = 622/867 (71%), Positives = 695/867 (80%), Gaps = 12/867 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT++NGRVLSFYSMPEYESWKESLGG A+GWSIKYYKGLGTSTSKEGKEYFKDL  HKKD
Sbjct: 573  ATHRNGRVLSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKD 632

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+WVDE+DGDAI+LAFSKKKIE RKNWLRQF+PGTYLDQKEKLIKYSDFVNKELILFSMA
Sbjct: 633  FMWVDEKDGDAIELAFSKKKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMA 692

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKIAQF+GYVSEHSAYHHGEQSL+STII
Sbjct: 693  DLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTII 752

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLL PNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDD LLDYL
Sbjct: 753  GMAQDFVGSNNINLLLPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYL 812

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEPT YVP IP VLVNGSEGIGTGWSS IPNYNPRDI+AN+R LLNGE MEPMD
Sbjct: 813  NEDGQSIEPTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMD 872

Query: 901  PWYKGFKGTIEKT-ATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMT 1077
            PWY+GF+GTIEKT  TK+    YTV GIIEE+NETTLRI+ELPVR+WTQDYKEFLESIMT
Sbjct: 873  PWYRGFRGTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMT 932

Query: 1078 GNDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFD 1257
            GNDKIK+PFIKDY+EHNDDTTVHFEVIMSEENL+MAK EGL++KFKLTT ISTSNMHLFD
Sbjct: 933  GNDKIKDPFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFD 992

Query: 1258 PKGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEII 1437
              G IKKY+TPEQIL+EFFHLRLEFYEKR                  VRFILGVVRGEII
Sbjct: 993  SNGTIKKYETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEII 1052

Query: 1438 VSNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIG-GKVRASDY 1614
            VSNRKRADLF EL +KGFTPFPKK KS+E A+AG  T+D EE E+N++ +  G VRA+DY
Sbjct: 1053 VSNRKRADLFHELHQKGFTPFPKKSKSVEIAVAG-ATDDTEEAEENTDAVSKGGVRATDY 1111

Query: 1615 EYLLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKND 1794
            EYLLSMAIG+LTLEKVQELCAD+D+L   VD+LK +TPK+LW+ DLDAL+++LDEQDKND
Sbjct: 1112 EYLLSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKND 1171

Query: 1795 AQAEVARKALKGKVMTEAGLKASR-VVKNPRKNNTKKANN-----PPIEATVSSAVEIGN 1956
            A+AE  RK LK +VM+EAG+K SR   KNPRKNN KKANN       ++ + SSA+E+ +
Sbjct: 1172 ARAEETRKQLKSRVMSEAGMKVSRQAPKNPRKNN-KKANNAEPAAETMDVSASSAMEMES 1230

Query: 1957 PSEVLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDS 2136
              EV+KPKGR  PRKAPAKK+E  T                  AAYNL+SSPD SAAM++
Sbjct: 1231 VPEVVKPKGRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEA 1290

Query: 2137 EVP----ARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGENDDSDGDFE 2304
            EVP    ARKKEPS+RAAA+K PL++FTEISDDD   +D+     EE    +    G  +
Sbjct: 1291 EVPQVPAARKKEPSRRAAAQKKPLASFTEISDDD---EDDEDFEVEEVSASDVKKKGGRK 1347

Query: 2305 PEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVENAGISPE 2484
            P                                    QLL Q L+T+  KP E  GISPE
Sbjct: 1348 PAANA--------KAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLGISPE 1399

Query: 2485 KKVRKMRASPFNKKSGSILGRIGTKDK 2565
            KKVRKMRASPFNKKSGS+LG  G +D+
Sbjct: 1400 KKVRKMRASPFNKKSGSVLGSTGEEDE 1426


>emb|CBI24922.3| unnamed protein product [Vitis vinifera]
          Length = 1452

 Score = 1147 bits (2966), Expect = 0.0
 Identities = 601/866 (69%), Positives = 667/866 (77%), Gaps = 11/866 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT++NGRVLSFYSMPEYESWKESLGG A+GWSIKYYKGLGTSTSKEGKEYFKDL  HKKD
Sbjct: 573  ATHRNGRVLSFYSMPEYESWKESLGGNASGWSIKYYKGLGTSTSKEGKEYFKDLGKHKKD 632

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+WVDE+DGDAI+LAFSKKKIE RKNWLRQF+PGTYLDQKEKLIKYSDFVNKELILFSMA
Sbjct: 633  FMWVDEKDGDAIELAFSKKKIEERKNWLRQFQPGTYLDQKEKLIKYSDFVNKELILFSMA 692

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKIAQF+GYVSEHSAYHHGEQSL+STII
Sbjct: 693  DLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKIAQFSGYVSEHSAYHHGEQSLASTII 752

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLL PNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDD LLDYL
Sbjct: 753  GMAQDFVGSNNINLLLPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDILLDYL 812

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEPT YVP IP VLVNGSEGIGTGWSS IPNYNPRDI+AN+R LLNGE MEPMD
Sbjct: 813  NEDGQSIEPTWYVPTIPMVLVNGSEGIGTGWSSSIPNYNPRDIIANVRRLLNGEMMEPMD 872

Query: 901  PWYKGFKGTIEKT-ATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMT 1077
            PWY+GF+GTIEKT  TK+    YTV GIIEE+NETTLRI+ELPVR+WTQDYKEFLESIMT
Sbjct: 873  PWYRGFRGTIEKTDPTKQESVGYTVKGIIEEVNETTLRISELPVRKWTQDYKEFLESIMT 932

Query: 1078 GNDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFD 1257
            GNDKIK+PFIKDY+EHNDDTTVHFEVIMSEENL+MAK EGL++KFKLTT ISTSNMHLFD
Sbjct: 933  GNDKIKDPFIKDYKEHNDDTTVHFEVIMSEENLLMAKQEGLLQKFKLTTKISTSNMHLFD 992

Query: 1258 PKGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEII 1437
              G IKKY+TPEQIL+EFFHLRLEFYEKR                  VRFILGVVRGEII
Sbjct: 993  SNGTIKKYETPEQILEEFFHLRLEFYEKRKRVLLDNLELELLKLENKVRFILGVVRGEII 1052

Query: 1438 VSNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYE 1617
            VSNRKRADLF EL +                                     KVRA+DYE
Sbjct: 1053 VSNRKRADLFHELHQ-------------------------------------KVRATDYE 1075

Query: 1618 YLLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDA 1797
            YLLSMAIG+LTLEKVQELCAD+D+L   VD+LK +TPK+LW+ DLDAL+++LDEQDKNDA
Sbjct: 1076 YLLSMAIGTLTLEKVQELCADRDKLNKGVDDLKKATPKALWITDLDALERELDEQDKNDA 1135

Query: 1798 QAEVARKALKGKVMTEAGLKASR-VVKNPRKNNTKKANN-----PPIEATVSSAVEIGNP 1959
            +AE  RK LK +VM+EAG+K SR   KNPRKNN KKANN       ++ + SSA+E+ + 
Sbjct: 1136 RAEETRKQLKSRVMSEAGMKVSRQAPKNPRKNN-KKANNAEPAAETMDVSASSAMEMESV 1194

Query: 1960 SEVLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSE 2139
             EV+KPKGR  PRKAPAKK+E  T                  AAYNL+SSPD SAAM++E
Sbjct: 1195 PEVVKPKGRAAPRKAPAKKKEMPTSVLKDEDDDEVHELKERLAAYNLESSPDGSAAMEAE 1254

Query: 2140 VP----ARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGENDDSDGDFEP 2307
            VP    ARKKEPS+RAAA+K PL++FTEISDDD   +D+     EE    +    G  +P
Sbjct: 1255 VPQVPAARKKEPSRRAAAQKKPLASFTEISDDD---EDDEDFEVEEVSASDVKKKGGRKP 1311

Query: 2308 EVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVENAGISPEK 2487
                                                QLL Q L+T+  KP E  GISPEK
Sbjct: 1312 AANA--------KAAAAKPAAAAAKNKRGAANKQQPQLLGQTLLTEIFKPAETLGISPEK 1363

Query: 2488 KVRKMRASPFNKKSGSILGRIGTKDK 2565
            KVRKMRASPFNKKSGS+LG  G +D+
Sbjct: 1364 KVRKMRASPFNKKSGSVLGSTGEEDE 1389


>ref|XP_007009327.1| DNA topoisomerase 2 isoform 1 [Theobroma cacao]
            gi|508726240|gb|EOY18137.1| DNA topoisomerase 2 isoform 1
            [Theobroma cacao]
          Length = 1473

 Score = 1107 bits (2863), Expect = 0.0
 Identities = 589/919 (64%), Positives = 688/919 (74%), Gaps = 12/919 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+K   VLSFYSMPEYE WKESLGG A GWSIKYYKGLGTSTSKEGK+YFK+L+ H+K+
Sbjct: 570  ATHKTKGVLSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKE 629

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            FVW DEQDG+AI+LAFSKKKIEARKNWLRQFEPGT+LDQ +KLIKYS+F+NKELILFSMA
Sbjct: 630  FVWQDEQDGEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMA 689

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSM+DGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STI+
Sbjct: 690  DLQRSIPSMIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIV 749

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLL P GQFGTR+QGGKD ASARYI+T LSPITR+LFPKDDDGLLDYL
Sbjct: 750  GMAQDFVGSNNINLLNPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYL 809

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEP  YVPIIP VLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM 
Sbjct: 810  NEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMH 869

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GFKG IEKTA+KEAG +YT++GIIEE++ETTLRITELPVRRWTQDY+EFLESI+TG
Sbjct: 870  PWYRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITG 929

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            ND    PFIK++R+++DDTTV FEVI++EEN+++AK EGL+KKFKLTTTISTSNMHLFD 
Sbjct: 930  ND----PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDS 985

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KG+IKKYDTPEQIL+EFFHLR EFYEKR                  VRFILGVV+GEIIV
Sbjct: 986  KGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIV 1045

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            +NRKRADLFLELQ KGFTPFPKK K++E A+AG  T+D EE E+NSEV    ++ASDY+Y
Sbjct: 1046 NNRKRADLFLELQTKGFTPFPKKAKTVEVAVAG-ATDDTEETEENSEVSAKGLQASDYDY 1104

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSMAIGSLTLEKVQELCAD+D+L  EV++L+ +TPKSLW+KDLD L+ QLDEQDK  AQ
Sbjct: 1105 LLSMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDK-AAQ 1163

Query: 1801 AEVARKALKGKVMTEAGLKASR-VVKNPRKNNTKKANNPPIEATV----SSAVEIGNPSE 1965
            AE A K +KG+   EAG +A R   K PRK N K+ N   +  T     SSA+E      
Sbjct: 1164 AEEAAKLVKGR--GEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETETAPA 1221

Query: 1966 VLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSE-- 2139
             +KPKGRGG RKA     +K                    A YNLDSSPD SAAM++E  
Sbjct: 1222 AVKPKGRGGSRKA-----KKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEVP 1276

Query: 2140 -VPARKKEPSKR-AAAKKPPLSTFTEISDDDGNM---DDEMQMIPEEKKGENDDSDGDFE 2304
             VPA KKEPSKR AAA+K P ++ +EIS+  G +   D++++++            G  +
Sbjct: 1277 QVPAGKKEPSKRAAAARKKPATSLSEISESIGEIDINDEDLEVVEVAAAAAPAGKKGGRK 1336

Query: 2305 PEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVENAGISPE 2484
            P                                   K+   QKL+T+ +KP E++GISPE
Sbjct: 1337 PAAN------------SKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGISPE 1384

Query: 2485 KKVRKMRASPFNKKSGSILGRIGTKDKDSSLMXXXXXXXXXXXXXXXXPDEVNEVXXXXX 2664
            KKVRKMRASPFNKKSGS+LGR+G K+ +S+                   +EV E+     
Sbjct: 1385 KKVRKMRASPFNKKSGSVLGRVG-KELEST---TDSEETFGSSSMSADTEEVTEIVPARP 1440

Query: 2665 XXXXXXXXXXKYVLSDSES 2721
                       YVLSDSE+
Sbjct: 1441 RPQRTNRKQTTYVLSDSET 1459


>ref|XP_007009328.1| DNA topoisomerase 2 isoform 2 [Theobroma cacao]
            gi|508726241|gb|EOY18138.1| DNA topoisomerase 2 isoform 2
            [Theobroma cacao]
          Length = 1285

 Score = 1104 bits (2855), Expect = 0.0
 Identities = 589/920 (64%), Positives = 689/920 (74%), Gaps = 13/920 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+K   VLSFYSMPEYE WKESLGG A GWSIKYYKGLGTSTSKEGK+YFK+L+ H+K+
Sbjct: 381  ATHKTKGVLSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKE 440

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            FVW DEQDG+AI+LAFSKKKIEARKNWLRQFEPGT+LDQ +KLIKYS+F+NKELILFSMA
Sbjct: 441  FVWQDEQDGEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMA 500

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSM+DGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STI+
Sbjct: 501  DLQRSIPSMIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIV 560

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLL P GQFGTR+QGGKD ASARYI+T LSPITR+LFPKDDDGLLDYL
Sbjct: 561  GMAQDFVGSNNINLLNPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYL 620

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEP  YVPIIP VLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM 
Sbjct: 621  NEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMH 680

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GFKG IEKTA+KEAG +YT++GIIEE++ETTLRITELPVRRWTQDY+EFLESI+TG
Sbjct: 681  PWYRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITG 740

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            ND    PFIK++R+++DDTTV FEVI++EEN+++AK EGL+KKFKLTTTISTSNMHLFD 
Sbjct: 741  ND----PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDS 796

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KG+IKKYDTPEQIL+EFFHLR EFYEKR                  VRFILGVV+GEIIV
Sbjct: 797  KGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIV 856

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            +NRKRADLFLELQ KGFTPFPKK K++E A+AG  T+D EE E+NSEV    ++ASDY+Y
Sbjct: 857  NNRKRADLFLELQTKGFTPFPKKAKTVEVAVAG-ATDDTEETEENSEVSAKGLQASDYDY 915

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSMAIGSLTLEKVQELCAD+D+L  EV++L+ +TPKSLW+KDLD L+ QLDEQDK  AQ
Sbjct: 916  LLSMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDK-AAQ 974

Query: 1801 AEVARKALKGKVMTEAGLKASR-VVKNPRKNNTKKANNPPIEATV----SSAVEIGNPS- 1962
            AE A K +KG+   EAG +A R   K PRK N K+ N   +  T     SSA+E    + 
Sbjct: 975  AEEAAKLVKGR--GEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETAETAP 1032

Query: 1963 EVLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSE- 2139
              +KPKGRGG RKA     +K                    A YNLDSSPD SAAM++E 
Sbjct: 1033 AAVKPKGRGGSRKA-----KKDDSDDDDDEDFGIPDLRERLAKYNLDSSPDHSAAMETEV 1087

Query: 2140 --VPARKKEPSKR-AAAKKPPLSTFTEISDDDGNM---DDEMQMIPEEKKGENDDSDGDF 2301
              VPA KKEPSKR AAA+K P ++ +EIS+  G +   D++++++            G  
Sbjct: 1088 PQVPAGKKEPSKRAAAARKKPATSLSEISESIGEIDINDEDLEVVEVAAAAAPAGKKGGR 1147

Query: 2302 EPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVENAGISP 2481
            +P                                   K+   QKL+T+ +KP E++GISP
Sbjct: 1148 KPAAN------------SKAAAKPPAAAKKRGPAAAGKKSQQQKLLTEMLKPAEDSGISP 1195

Query: 2482 EKKVRKMRASPFNKKSGSILGRIGTKDKDSSLMXXXXXXXXXXXXXXXXPDEVNEVXXXX 2661
            EKKVRKMRASPFNKKSGS+LGR+G K+ +S+                   +EV E+    
Sbjct: 1196 EKKVRKMRASPFNKKSGSVLGRVG-KELEST---TDSEETFGSSSMSADTEEVTEIVPAR 1251

Query: 2662 XXXXXXXXXXXKYVLSDSES 2721
                        YVLSDSE+
Sbjct: 1252 PRPQRTNRKQTTYVLSDSET 1271


>ref|XP_006439079.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
            gi|557541275|gb|ESR52319.1| hypothetical protein
            CICLE_v10030505mg [Citrus clementina]
          Length = 1456

 Score = 1085 bits (2807), Expect = 0.0
 Identities = 580/919 (63%), Positives = 685/919 (74%), Gaps = 12/919 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            ATNKNG+VLSFYSMP+YE+WKESLGG A+ WSIKYYKGLGTSTSKEGKEYF+++ LHKKD
Sbjct: 569  ATNKNGKVLSFYSMPDYEAWKESLGGNASSWSIKYYKGLGTSTSKEGKEYFQNITLHKKD 628

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            FVW D+QDG+AI+LAFSKKKIEARK WL QFEPG +LDQKEK IKYSDFVNKELILFSMA
Sbjct: 629  FVWEDDQDGEAIELAFSKKKIEARKKWLLQFEPGNHLDQKEKYIKYSDFVNKELILFSMA 688

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAK+AQF+GYVSEHSAYHHGEQSL+STI+
Sbjct: 689  DLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIL 748

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLLQPNGQFGTR+QGGKD ASARYI+TRLSPITRFLFPKDDD LLDYL
Sbjct: 749  GMAQDFVGSNNINLLQPNGQFGTRNQGGKDAASARYIFTRLSPITRFLFPKDDDKLLDYL 808

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQ IEPT Y+PIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM 
Sbjct: 809  NEDGQQIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMH 868

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GF+GTIEKTA+KEAG +YTV+GIIEE+NETTLRI ELP+RRWTQDY+EFLESI+  
Sbjct: 869  PWYRGFRGTIEKTASKEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQ 928

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            ND     FI+ +R+++DDTTV FEV +SEE+++  K EGL+KKFKLTTTISTSNMHLFD 
Sbjct: 929  NDS----FIRGFRQYSDDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLFDS 984

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KGVIKKYDTPEQIL+EFFH+RLEFYEKR                  VRFILGVV GEI+V
Sbjct: 985  KGVIKKYDTPEQILEEFFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVV 1044

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            +NRKR DL LEL++KGFTPFPK  KSIEA +AG  T++ EE+E+N EV+ G V++ DY+Y
Sbjct: 1045 NNRKRTDLLLELRQKGFTPFPKNSKSIEAVVAG-ATDETEESEENPEVVNG-VQSIDYDY 1102

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSMAIG+LTLEKVQ L AD+D+L  EVD+L+ +TP+SLW+KDLDALD QLDE DK+DA+
Sbjct: 1103 LLSMAIGTLTLEKVQGLLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLDELDKSDAR 1162

Query: 1801 AEVARKALKGKVMTEAGLK--ASRVVKNPRKNNTKKANNPPIEATVSSAV-EIGNPSEVL 1971
            AE  R  +KG   ++AG K  A R  KN RKN+ KK+NN    A  + A+ E+ N ++V+
Sbjct: 1163 AEEERMKIKGNGNSDAGPKIVAKRAPKNARKND-KKSNN----ARATEAMGEMDNVTKVV 1217

Query: 1972 KPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSE---V 2142
            KPKGR G +KAPA+K +                     A+  L+ SPDQS  M++E   V
Sbjct: 1218 KPKGRAGLKKAPAEKLDDEEEDEVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEKVQV 1277

Query: 2143 PARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQM---IPEEKKGENDDSDGD---FE 2304
            PA+KKEPSKR AA+K  ++  T  S+D+  +DD+       PE  K     + G+    +
Sbjct: 1278 PAKKKEPSKRTAAQKKAVTVETSDSEDEIIIDDDEAFEIAAPEAGKKGGRKAAGNTKAAK 1337

Query: 2305 PEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVENAGISPE 2484
            P VE                                +  L Q+L+T+ +KP E+   SPE
Sbjct: 1338 PAVET--------------------KKRGPAKKQQPEASLGQRLLTEMLKPTES---SPE 1374

Query: 2485 KKVRKMRASPFNKKSGSILGRIGTKDKDSSLMXXXXXXXXXXXXXXXXPDEVNEVXXXXX 2664
            KKVRKMRASPFNKKSGS+LGR GT ++ S                    +EV EV     
Sbjct: 1375 KKVRKMRASPFNKKSGSMLGRAGTIEEPSG-------------SSPSTSEEVAEVLPPKA 1421

Query: 2665 XXXXXXXXXXKYVLSDSES 2721
                      +YVLSDSES
Sbjct: 1422 RPQRANRRQARYVLSDSES 1440


>ref|XP_006482851.1| PREDICTED: DNA topoisomerase 2-like [Citrus sinensis]
          Length = 1456

 Score = 1084 bits (2803), Expect = 0.0
 Identities = 579/919 (63%), Positives = 684/919 (74%), Gaps = 12/919 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            ATNKNG+VLSFYSMP+YE+WKESLGG A+ WSIKYYKGLGTSTSKEGKEYF+++ LHKKD
Sbjct: 569  ATNKNGKVLSFYSMPDYEAWKESLGGNASSWSIKYYKGLGTSTSKEGKEYFQNITLHKKD 628

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            FVW D+QDG+AI+LAFSKKKIEARK WL QFEPG +LDQKEK IKYSDFVNKELILFSMA
Sbjct: 629  FVWEDDQDGEAIELAFSKKKIEARKKWLLQFEPGNHLDQKEKYIKYSDFVNKELILFSMA 688

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAK+AQF+GYVSEHSAYHHGEQSL+STI+
Sbjct: 689  DLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIL 748

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLLQPNGQFGTR+QGGKD ASARYI+TRLSPITRFLFPKDDD LLDYL
Sbjct: 749  GMAQDFVGSNNINLLQPNGQFGTRNQGGKDAASARYIFTRLSPITRFLFPKDDDKLLDYL 808

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQ IEPT Y+PIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM 
Sbjct: 809  NEDGQQIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMH 868

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GF+GTIEKTA+KEAG +YTV+GIIEE+NETTLRI ELP+RRWTQDY+EFLESI+  
Sbjct: 869  PWYRGFRGTIEKTASKEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQ 928

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            ND     FI+ +R+++DDTTV FEV +SEE+++  K EGL+KKFKLTTTISTSNMHLFD 
Sbjct: 929  NDS----FIRGFRQYSDDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLFDS 984

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KGVIKKYDTPEQIL+EFFH+RLEFYEKR                  VRFILGVV GEI+V
Sbjct: 985  KGVIKKYDTPEQILEEFFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVV 1044

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            +NRKR DL LEL++KGFTPFPK  KSIEA +AG  T++ EE+E+N EV+ G V++ DY+Y
Sbjct: 1045 NNRKRTDLLLELRQKGFTPFPKNSKSIEAVVAG-ATDETEESEENPEVVNG-VQSIDYDY 1102

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSMAIG+LTLEKVQ L AD+D+L  EVD+L+ +TP+SLW+KDLDALD QLDE DK+DA+
Sbjct: 1103 LLSMAIGTLTLEKVQGLLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLDELDKSDAR 1162

Query: 1801 AEVARKALKGKVMTEAGLK--ASRVVKNPRKNNTKKANNPPIEATVSSAV-EIGNPSEVL 1971
            AE  R  +KG   ++AG K  A R  KN RKN+ KK+NN    A  + A+ E+ N ++V+
Sbjct: 1163 AEEERMKIKGNGNSDAGPKIVAKRAPKNARKND-KKSNN----ARATEAMGEMDNVTKVV 1217

Query: 1972 KPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSE---V 2142
            KPKGR G +KAPA+K +                     A+  L+ SPDQS  M++E   V
Sbjct: 1218 KPKGRAGLKKAPAEKLDDEEEDEVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEKVQV 1277

Query: 2143 PARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQM---IPEEKKGENDDSDGD---FE 2304
            PA+KKEPSKR AA+K  ++  T  S+D+  +DD+       PE  K     + G+    +
Sbjct: 1278 PAKKKEPSKRTAAQKKAVTVETSDSEDEIIIDDDEAFEIAAPEAGKKGGRKAAGNTKAAK 1337

Query: 2305 PEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVENAGISPE 2484
            P  E                                +  L Q+L+T+ +KP E+   SPE
Sbjct: 1338 PAAET--------------------KKRGPAKKQQPEASLGQRLLTEMLKPTES---SPE 1374

Query: 2485 KKVRKMRASPFNKKSGSILGRIGTKDKDSSLMXXXXXXXXXXXXXXXXPDEVNEVXXXXX 2664
            KKVRKMRASPFNKKSGS+LGR GT ++ S                    +EV EV     
Sbjct: 1375 KKVRKMRASPFNKKSGSMLGRAGTIEEPSG-------------SSPSTSEEVAEVLPPKA 1421

Query: 2665 XXXXXXXXXXKYVLSDSES 2721
                      +YVLSDSES
Sbjct: 1422 RPQRANRRQARYVLSDSES 1440


>gb|EXB68160.1| DNA topoisomerase 2 [Morus notabilis]
          Length = 1451

 Score = 1080 bits (2792), Expect = 0.0
 Identities = 574/920 (62%), Positives = 673/920 (73%), Gaps = 16/920 (1%)
 Frame = +1

Query: 10   KNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKDFVW 189
            KNG+ L+FY+MPEYE+WK+SL G A+GWSIKYYKGLGTSTSKEG+EYF++L+ HKKDF+W
Sbjct: 541  KNGKELAFYTMPEYEAWKDSLRGNASGWSIKYYKGLGTSTSKEGREYFQNLDKHKKDFLW 600

Query: 190  VDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMADLQ 369
            +DEQDG+AI+LAFSKKKIE RKNWLR+FEPGT+LDQKEKLIKYSDFV+KELILFS+ADLQ
Sbjct: 601  IDEQDGEAIELAFSKKKIEERKNWLRRFEPGTHLDQKEKLIKYSDFVHKELILFSLADLQ 660

Query: 370  RSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTIIGMA 549
            RSIPSMVDGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+ TIIGMA
Sbjct: 661  RSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLAGTIIGMA 720

Query: 550  QDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYLNED 729
            QD+VGSNNINLL PNGQFGTR+ GGKDHASARYI+T+LSPITR LFPKDDD LLD+LNED
Sbjct: 721  QDFVGSNNINLLMPNGQFGTRNLGGKDHASARYIFTQLSPITRSLFPKDDDLLLDFLNED 780

Query: 730  GQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMDPWY 909
            G SIEPT YVPIIPTVL NGSEGIGTGWSSYIPNYNPRDIVAN+R LL+G+ M PM PWY
Sbjct: 781  GLSIEPTWYVPIIPTVLANGSEGIGTGWSSYIPNYNPRDIVANVRRLLDGDEMVPMIPWY 840

Query: 910  KGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTGNDK 1089
            +GFKGTIEK++ +   AS+ VSG++EE+NETT+RITELP+RRWTQDYKEFL+SI  GNDK
Sbjct: 841  RGFKGTIEKSSKE---ASFFVSGLMEEVNETTVRITELPIRRWTQDYKEFLDSICYGNDK 897

Query: 1090 IKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDPKGV 1269
             K+PFI+D+ +H+D +TV   V ++EE L+  K EGL+KK KLTT+IST+NMHLFD  GV
Sbjct: 898  AKDPFIEDFTQHSDHSTVDILVHLAEETLIAVKQEGLLKKLKLTTSISTANMHLFDANGV 957

Query: 1270 IKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIVSNR 1449
            IKKYDTPEQIL+EF+HLRLEFYEKR                  VRFILGVV GEI+VSNR
Sbjct: 958  IKKYDTPEQILEEFYHLRLEFYEKRKKALLDNLELELLKLANKVRFILGVVTGEIVVSNR 1017

Query: 1450 KRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNS--EVIGGKVRASDYEYL 1623
            KRADLF+ELQ+KGFTPFPKK K++E  +AGV TEDAE+ E+NS  E I  + R SDYEYL
Sbjct: 1018 KRADLFVELQRKGFTPFPKKTKAVEPEVAGV-TEDAEDTEENSNAEAISTEARISDYEYL 1076

Query: 1624 LSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQA 1803
            LSMAIG+LTLEKVQ LC +KD+L NEV+EL+ +TPKSLW+KDLDAL+ QLDE +K+DAQA
Sbjct: 1077 LSMAIGTLTLEKVQALCGEKDKLNNEVEELRKATPKSLWVKDLDALETQLDELNKSDAQA 1136

Query: 1804 EVARKALKGKVMTEAGLKASRVVKNPRKNNTKKANNPPIEATVS----SAVEIGNPSEVL 1971
            E ARK  KG+V   A  K SR      + NTKKA+N    A ++    SA+E     EV 
Sbjct: 1137 EEARKKSKGQVKNAAVSKVSRQAPKVPRKNTKKASNAEAIADITENFDSAMEFEKAPEVA 1196

Query: 1972 KPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSE---V 2142
            KPKGR GP+KA +K                        AAYNLDSSPD+S+ MD+E   V
Sbjct: 1197 KPKGRAGPKKAASKV----VVEDDDDDDDEVLALKDRLAAYNLDSSPDKSSEMDTEAPQV 1252

Query: 2143 PARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGENDDSDGDFE-----P 2307
            P  KK P+KRAAA+K  L+T +E  + D + DDE+            D D DFE     P
Sbjct: 1253 PVPKKAPTKRAAAQKKTLATVSETVNLDDDDDDEI------------DGDEDFELESTAP 1300

Query: 2308 EVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNK--QLLNQKLITDTMKPVENAGISP 2481
                                              NK  Q+L QKL+TD +KP EN+G+SP
Sbjct: 1301 AKAAAKKGGKKPAVSTKAVSKAPAAAATKRRGAANKEPQVLGQKLLTDMLKPAENSGLSP 1360

Query: 2482 EKKVRKMRASPFNKKSGSILGRIGTKDKDSSLMXXXXXXXXXXXXXXXXPDEVNEVXXXX 2661
            EKKVRKMRASPFNKKSGS+LGR    D D                     D+V EV    
Sbjct: 1361 EKKVRKMRASPFNKKSGSVLGRAVNIDDDDEATTASQENSPSTSESV---DDVVEVPASK 1417

Query: 2662 XXXXXXXXXXXKYVLSDSES 2721
                       +YVLSDSES
Sbjct: 1418 ARPQRANRTQARYVLSDSES 1437


>ref|XP_006345427.1| PREDICTED: DNA topoisomerase 2-like [Solanum tuberosum]
          Length = 1485

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 554/864 (64%), Positives = 663/864 (76%), Gaps = 6/864 (0%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+K+GR+L+FY+MPEYE+W+ SLG T++GWSIKYYKGLGTSTSKEGKEYF+DL+ H+KD
Sbjct: 570  ATHKSGRILAFYTMPEYEAWRRSLGATSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKD 629

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+W D QDG++I+LAFSKKKIEARKNWLRQFEPGT+LDQKEK I Y++FVNKELILFSMA
Sbjct: 630  FIWADNQDGESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMA 689

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSM+DGLKPGQRKILFC+FKRNFVKEAK++QF+GYVSEHSAYHHGEQSLSSTII
Sbjct: 690  DLQRSIPSMLDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTII 749

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQDYVGSNN+NLLQPNGQFGTR+ GGKDHAS+RYIYTRLSPI RFLFPKDDD +LDYL
Sbjct: 750  GMAQDYVGSNNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKDDDTVLDYL 809

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEPT Y+PIIP VLVNGSEGIGTGWSSY+PNYNPRD+VAN+R LLN E MEPMD
Sbjct: 810  NEDGQSIEPTWYIPIIPMVLVNGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDELMEPMD 869

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWYKGFKGTIEKTATKE GA+YTV+GIIEE +ETTLRI+ELPVRRWT+DYK+FLES+   
Sbjct: 870  PWYKGFKGTIEKTATKETGATYTVTGIIEEFSETTLRISELPVRRWTEDYKQFLESMTVS 929

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
             DK K+ FIK+ R + D+ +V FEVIMSEENL++A+ EGL+KKFKLTTTISTSNMHLFD 
Sbjct: 930  TDKSKDAFIKEVRAYGDENSVCFEVIMSEENLLLAQQEGLLKKFKLTTTISTSNMHLFDS 989

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KG IKKYD PE+IL+EF+H+RLE+YEKR                  VRFILGVV+GEIIV
Sbjct: 990  KGKIKKYDAPEEILEEFYHVRLEYYEKRKKTLLEILELELLRIENKVRFILGVVKGEIIV 1049

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            +NRKRADL LEL+ KGFTPFPKK K +EA +A  +T+DAE++E++ E     VRASDY+Y
Sbjct: 1050 NNRKRADLLLELKNKGFTPFPKK-KPVEAVVAD-STDDAEDSEESPEESNKGVRASDYDY 1107

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSMAIG+LTLEKVQELCAD+D+L  EV++++++TPK LWMKDLD LDKQLDEQDK D Q
Sbjct: 1108 LLSMAIGTLTLEKVQELCADRDKLNAEVEDMRNATPKDLWMKDLDVLDKQLDEQDKLDIQ 1167

Query: 1801 AEVARKALKGKVMTEAGLKASRVVKNPRKNNTKKA----NNPPIEATVSSAVEIGNPSEV 1968
             E AR+ LK KVM  AG KA +    PRK   K A       P++ +V S  E  N +EV
Sbjct: 1168 TEEAREKLKKKVMNAAG-KAPK--PKPRKTTKKAAVVESTAEPMDVSVGSMAETANVTEV 1224

Query: 1969 LKPKGR-GGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSEVP 2145
             KPKGR GG +KAPAK   K                    AAYNL+SSPD+S   ++E P
Sbjct: 1225 AKPKGRGGGSKKAPAK--AKPVVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEAP 1282

Query: 2146 -ARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGENDDSDGDFEPEVEVV 2322
             A+ K P+KRAAA+K  L +  ++S+     +DE+++            D +F PEV V 
Sbjct: 1283 KAQTKAPAKRAAAQKKALPSTPDVSEG----EDEIEI----------SDDNEFAPEVAVG 1328

Query: 2323 XXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVENAGISPEKKVRKM 2502
                                           Q + Q+LIT  +KP E+AG+SP++KVRKM
Sbjct: 1329 GKKKGGRKPAAAKAAAAPKPPKKRAPANKQSQSVGQRLITQVLKPAEDAGVSPDRKVRKM 1388

Query: 2503 RASPFNKKSGSILGRIGTKDKDSS 2574
            R SPFNKKSG+++GR  +    +S
Sbjct: 1389 RESPFNKKSGAVMGRNTSSSSSTS 1412


>ref|XP_006439078.1| hypothetical protein CICLE_v10030505mg [Citrus clementina]
            gi|557541274|gb|ESR52318.1| hypothetical protein
            CICLE_v10030505mg [Citrus clementina]
          Length = 1455

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 579/919 (63%), Positives = 684/919 (74%), Gaps = 12/919 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            ATNKNG+VLSFYSMP+YE+WKESLGG A+ WSIKYYKGLGTSTSKEGKEYF+++ LHKKD
Sbjct: 569  ATNKNGKVLSFYSMPDYEAWKESLGGNASSWSIKYYKGLGTSTSKEGKEYFQNITLHKKD 628

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            FVW D+QDG+AI+LAFSKKKIEARK WL QFEPG +LDQKEK IKYSDFVNKELILFSMA
Sbjct: 629  FVWEDDQDGEAIELAFSKKKIEARKKWLLQFEPGNHLDQKEKYIKYSDFVNKELILFSMA 688

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAK+AQF+GYVSEHSAYHHGEQSL+STI+
Sbjct: 689  DLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTIL 748

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLLQPNGQFGTR+QGGKD ASARYI+TRLSPITRFLFPKDDD LLDYL
Sbjct: 749  GMAQDFVGSNNINLLQPNGQFGTRNQGGKDAASARYIFTRLSPITRFLFPKDDDKLLDYL 808

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQ IEPT Y+PIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM 
Sbjct: 809  NEDGQQIEPTWYMPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEMMEPMH 868

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GF+GTIEKTA+KEAG +YTV+GIIEE+NETTLRI ELP+RRWTQDY+EFLESI+  
Sbjct: 869  PWYRGFRGTIEKTASKEAGVTYTVTGIIEEVNETTLRIKELPIRRWTQDYREFLESIIDQ 928

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            ND     FI+ +R+++DDTTV FEV +SEE+++  K EGL+KKFKLTTTISTSNMHLFD 
Sbjct: 929  NDS----FIRGFRQYSDDTTVDFEVFLSEESMMRTKQEGLLKKFKLTTTISTSNMHLFDS 984

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KGVIKKYDTPEQIL+EFFH+RLEFYEKR                  VRFILGVV GEI+V
Sbjct: 985  KGVIKKYDTPEQILEEFFHIRLEFYEKRKKVQLENLELELLKLENKVRFILGVVNGEIVV 1044

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            +NRKR DL LEL++KGFTPFPK  KSIEA +AG  T++ EE+E+N EV+ G V++ DY+Y
Sbjct: 1045 NNRKRTDLLLELRQKGFTPFPKNSKSIEAVVAG-ATDETEESEENPEVVNG-VQSIDYDY 1102

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSMAIG+LTLEKVQ L AD+D+L  EVD+L+ +TP+SLW+KDLDALD QLD  DK+DA+
Sbjct: 1103 LLSMAIGTLTLEKVQGLLADRDKLNEEVDDLRKATPESLWVKDLDALDMQLD-LDKSDAR 1161

Query: 1801 AEVARKALKGKVMTEAGLK--ASRVVKNPRKNNTKKANNPPIEATVSSAV-EIGNPSEVL 1971
            AE  R  +KG   ++AG K  A R  KN RKN+ KK+NN    A  + A+ E+ N ++V+
Sbjct: 1162 AEEERMKIKGNGNSDAGPKIVAKRAPKNARKND-KKSNN----ARATEAMGEMDNVTKVV 1216

Query: 1972 KPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSE---V 2142
            KPKGR G +KAPA+K +                     A+  L+ SPDQS  M++E   V
Sbjct: 1217 KPKGRAGLKKAPAEKLDDEEEDEVPDLKQRLAKLNEQLASTKLEPSPDQSGVMETEKVQV 1276

Query: 2143 PARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQM---IPEEKKGENDDSDGD---FE 2304
            PA+KKEPSKR AA+K  ++  T  S+D+  +DD+       PE  K     + G+    +
Sbjct: 1277 PAKKKEPSKRTAAQKKAVTVETSDSEDEIIIDDDEAFEIAAPEAGKKGGRKAAGNTKAAK 1336

Query: 2305 PEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVENAGISPE 2484
            P VE                                +  L Q+L+T+ +KP E+   SPE
Sbjct: 1337 PAVET--------------------KKRGPAKKQQPEASLGQRLLTEMLKPTES---SPE 1373

Query: 2485 KKVRKMRASPFNKKSGSILGRIGTKDKDSSLMXXXXXXXXXXXXXXXXPDEVNEVXXXXX 2664
            KKVRKMRASPFNKKSGS+LGR GT ++ S                    +EV EV     
Sbjct: 1374 KKVRKMRASPFNKKSGSMLGRAGTIEEPSG-------------SSPSTSEEVAEVLPPKA 1420

Query: 2665 XXXXXXXXXXKYVLSDSES 2721
                      +YVLSDSES
Sbjct: 1421 RPQRANRRQARYVLSDSES 1439


>ref|XP_002298421.2| DNA topoisomerase family protein [Populus trichocarpa]
            gi|550348289|gb|EEE83226.2| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 1485

 Score = 1077 bits (2784), Expect = 0.0
 Identities = 572/873 (65%), Positives = 661/873 (75%), Gaps = 19/873 (2%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT++NG VLSFYSMPEYESWK SL G A+GWSIKYYKGLGTSTSKEGK YF+ L+ HKKD
Sbjct: 587  ATHRNGTVLSFYSMPEYESWKGSLAGNASGWSIKYYKGLGTSTSKEGKAYFQSLDKHKKD 646

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+W+DEQDGDAI+LAFSKKKIEARKNWLRQ+EPGT+LDQ +KLIKYSDF+NKELILFSMA
Sbjct: 647  FIWMDEQDGDAIELAFSKKKIEARKNWLRQYEPGTHLDQNQKLIKYSDFINKELILFSMA 706

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKI+QF+GYVSEHSAYHHGEQSL+STII
Sbjct: 707  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKISQFSGYVSEHSAYHHGEQSLASTII 766

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLL PNGQFGTR  GGKDHASARYIYT+LSPITRFLFPKDDDGLLDYL
Sbjct: 767  GMAQDFVGSNNINLLLPNGQFGTRSVGGKDHASARYIYTQLSPITRFLFPKDDDGLLDYL 826

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            +EDGQ+IEP  Y+PIIP VLVNG EGIGTGWS++IPNYNPRDIVANIR LLNGE MEPM+
Sbjct: 827  DEDGQTIEPNWYMPIIPMVLVNGCEGIGTGWSTFIPNYNPRDIVANIRRLLNGEMMEPMN 886

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GFKGTIEK A+KEAG SYTV+G+I E+NETTLRITELP+RRWT DYK FL S+  G
Sbjct: 887  PWYRGFKGTIEKGASKEAGCSYTVNGVINEVNETTLRITELPIRRWTDDYKAFLNSVTEG 946

Query: 1081 N-----DKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNM 1245
            N     +  K+PFIKD+R++ DD TV FEV++SEEN+++AK EGL+KKFKLTTTISTSNM
Sbjct: 947  NRDENGNLPKDPFIKDFRKYGDDATVVFEVLLSEENMMIAKQEGLLKKFKLTTTISTSNM 1006

Query: 1246 HLFDPKGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVR 1425
            HLFD  GVIKKYD PEQIL+EFFHLRLE+YE+R                  VRFILGVVR
Sbjct: 1007 HLFDSAGVIKKYDNPEQILEEFFHLRLEYYERRKKVLLENLEFELLKLENKVRFILGVVR 1066

Query: 1426 GEIIVSNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRA 1605
            GEIIV+NRKRADLFLEL +KGFTP PKK K++ A      T+D +E ED+ EV G  VRA
Sbjct: 1067 GEIIVNNRKRADLFLELHQKGFTPIPKKSKAVVAG----ATDDKDEAEDSLEVSG--VRA 1120

Query: 1606 SDYEYLLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQD 1785
            SDY+YLLSMAIG+LTLEKVQ+LCAD D+L  EVD L+ +TP  LW+KDL+AL+ QLD  D
Sbjct: 1121 SDYDYLLSMAIGTLTLEKVQQLCADHDKLNGEVDNLRKTTPIVLWVKDLEALEMQLDVLD 1180

Query: 1786 KNDAQAEVARKALKGKVMTEAGLKASRVV-KNPRKNNTKKANNPPIEATV-----SSAVE 1947
            K DA+AE ARK LKG    EAG K S+   KNPRK  TKKA N  +         SSA+E
Sbjct: 1181 KYDAEAEEARKKLKGDANGEAGFKVSKQAPKNPRKY-TKKAINEEVSVETMGKASSSAME 1239

Query: 1948 IGNPSEVLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAA 2127
              N +EV+KPKGR G RKAPAKKQEK +                   AY LDSSP+QSA 
Sbjct: 1240 TENAAEVVKPKGRAGSRKAPAKKQEKPSPISDEDDEIESLKDRLK--AYRLDSSPEQSAD 1297

Query: 2128 MDSEVPARKKEPSKRAAAKKPPLSTFTEISD--DDGNMDDEMQM----IPEEKK--GEND 2283
            M++EV    + P+ R AA+K PL+  + ISD  D+ ++DD+  +    +PE KK  G   
Sbjct: 1298 METEV---LRVPAGRKAARKKPLAAVSVISDSEDEPDLDDDFDVQVKAVPETKKKGGRKA 1354

Query: 2284 DSDGDFEPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVE 2463
             +  D   +                                   Q L Q+L+T+ +KP E
Sbjct: 1355 AAANDKAAKPPAATKRRGPASK--------------------QSQGLGQQLLTEMLKPAE 1394

Query: 2464 NAGISPEKKVRKMRASPFNKKSGSILGRIGTKD 2562
             +GISPEKKVRKMRASPFNKKSGS+LG I   D
Sbjct: 1395 ESGISPEKKVRKMRASPFNKKSGSLLGGIHKGD 1427


>ref|XP_004229644.1| PREDICTED: DNA topoisomerase 2-like [Solanum lycopersicum]
          Length = 1477

 Score = 1073 bits (2776), Expect = 0.0
 Identities = 546/860 (63%), Positives = 659/860 (76%), Gaps = 2/860 (0%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+K+GR+L+FY+MPEYE+W+ SLG T++GWSIKYYKGLGTSTSKEGKEYF+DL+ H+KD
Sbjct: 570  ATHKSGRILAFYTMPEYEAWRRSLGATSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKD 629

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            FVW D QDG++I+LAFSKKKIEARKNWLRQFEPGT+LDQKEK I Y++FVNKELILFSMA
Sbjct: 630  FVWADNQDGESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMA 689

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSM+DGLKPGQRKILFC+FKRNFVKEAK++QF+GYVSEHSAYHHGEQSLSSTII
Sbjct: 690  DLQRSIPSMLDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTII 749

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQDYVGSNN+NLLQPNGQFGTR+ GGKDHAS+RYIYTRLSPI RFLFPKDDD +LDYL
Sbjct: 750  GMAQDYVGSNNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKDDDTILDYL 809

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEPT YVP+IPTVLVNGSEGIGTGWSSY+PNYNPRD+VAN+R LLN E MEPMD
Sbjct: 810  NEDGQSIEPTWYVPVIPTVLVNGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDELMEPMD 869

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWYKGFKG IEKTATKE GA+YTV+GIIEE++ETTLRI+ELPVRRWT+DYK+FLES+   
Sbjct: 870  PWYKGFKGKIEKTATKETGATYTVTGIIEEVSETTLRISELPVRRWTEDYKQFLESMTVS 929

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
             DK K+ FIK+ R + D+ +V FEVIMSE+NL++A+ EGL+KKFKLTTTISTSNMHLFD 
Sbjct: 930  TDKAKDSFIKEVRAYGDENSVCFEVIMSEDNLLLAQQEGLLKKFKLTTTISTSNMHLFDS 989

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KG IKKYD PE+IL+EF+H+RLE+YEKR                  V+FILGVV+GEIIV
Sbjct: 990  KGKIKKYDAPEEILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKGEIIV 1049

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            +NRKRA+L LEL+ KGFTPFPKK K +EA +A  +T+DA+++E++ E     VRASDY+Y
Sbjct: 1050 NNRKRAELLLELKNKGFTPFPKK-KPVEAVVAD-STDDADDSEESPEESSRGVRASDYDY 1107

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSMAIG+LTLEKVQELCAD+D+L  EV++++++TPK LWMKDLD LDKQLDEQDK D Q
Sbjct: 1108 LLSMAIGTLTLEKVQELCADRDKLNAEVEDMRNATPKHLWMKDLDVLDKQLDEQDKIDIQ 1167

Query: 1801 AEVARKALKGKVMTEAGLKASRVVKNPRKNNTK-KANNPPIEATVSSAVEIGNPSEVLKP 1977
             E AR+ LK KVM  AG  A +    PRK N K ++    ++ +  S  E  N SEV+KP
Sbjct: 1168 TEEAREKLKKKVMNAAGKAAPK--PKPRKTNKKAESTAESMDVSFGSTAETANVSEVVKP 1225

Query: 1978 KGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSEVP-ARK 2154
            KGRG P KA      K                    AAYNL+SSPD+S   ++EVP A+ 
Sbjct: 1226 KGRGRPAKA------KPIVVEDEEEEDEVLALKDRLAAYNLNSSPDRSEVTETEVPKAQT 1279

Query: 2155 KEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGENDDSDGDFEPEVEVVXXXX 2334
            K P+KRAAA+K  L +  ++SD +  ++ +               D +FEP   V     
Sbjct: 1280 KAPAKRAAAQKKALPSTPDVSDGEDAIEID---------------DDEFEPAAAVGGKKK 1324

Query: 2335 XXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKPVENAGISPEKKVRKMRASP 2514
                                       Q + Q+LIT  +KP E+AG+SP++KVRKMRASP
Sbjct: 1325 GGRKPAAAKAAAAPKPPGKKAPANNQSQSVGQRLITQVLKPAEDAGVSPDRKVRKMRASP 1384

Query: 2515 FNKKSGSILGRIGTKDKDSS 2574
            FNKKSG+++G+  +    SS
Sbjct: 1385 FNKKSGAVMGKNTSSSSTSS 1404


>gb|AAN85207.1| DNA topoisomerase II [Nicotiana tabacum] gi|26984168|gb|AAN85208.1|
            DNA topoisomerase II [Nicotiana tabacum]
          Length = 1482

 Score = 1067 bits (2760), Expect = 0.0
 Identities = 564/918 (61%), Positives = 681/918 (74%), Gaps = 11/918 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+K+G++LSFY+MPEYESW++SLG  ++GWSIKYYKGLGTSTSKEGKEYF+DL+ H+KD
Sbjct: 569  ATHKSGKILSFYTMPEYESWRKSLGANSSGWSIKYYKGLGTSTSKEGKEYFQDLQKHRKD 628

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+W D QDG++I+LAFSKKKIEARKNWLRQFEPGT+LDQKEK I Y++FVNKELILFSMA
Sbjct: 629  FIWADNQDGESIELAFSKKKIEARKNWLRQFEPGTHLDQKEKYISYTEFVNKELILFSMA 688

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSM+DGLKPGQRKILFC+FKRNFVKEAK++QF+GYVSEHSAYHHGEQSLSSTII
Sbjct: 689  DLQRSIPSMLDGLKPGQRKILFCAFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLSSTII 748

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQDYVGSNN+NLLQPNGQFGTR+ GGKDHAS+RYIYTRLSPI RFLFPK+DD + DYL
Sbjct: 749  GMAQDYVGSNNVNLLQPNGQFGTRNMGGKDHASSRYIYTRLSPIARFLFPKEDDTIHDYL 808

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQ IEPT YVPI+P VL+NGSEGIGTGWSSY+PNYNPRD+VAN+R LLN EPMEPMD
Sbjct: 809  NEDGQYIEPTWYVPIVPMVLINGSEGIGTGWSSYVPNYNPRDLVANVRRLLNDEPMEPMD 868

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWYKGFKGTIEKTATKEAGA+YTV+GIIEE+NETTLRI+ELPVRRWT+DYK+FLES+   
Sbjct: 869  PWYKGFKGTIEKTATKEAGATYTVTGIIEEVNETTLRISELPVRRWTEDYKQFLESMTVS 928

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            NDK K+PFIK+ R + D+ +V FEVIMSEENL++A+ EGL+KKFKL TTISTSNMHLFD 
Sbjct: 929  NDKAKDPFIKEVRAYGDENSVCFEVIMSEENLILAQQEGLLKKFKLATTISTSNMHLFDS 988

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
             G IKKYD PE IL+EF+H+RLE+YEKR                  V+FILGVV+ EIIV
Sbjct: 989  NGKIKKYDNPEDILEEFYHVRLEYYEKRKKALLEILELELLRIENKVKFILGVVKVEIIV 1048

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            +NRKRADL LEL++KGFTPFPKK K++EA +A  T++DAE++E   E +   VRA DY+Y
Sbjct: 1049 NNRKRADLLLELKEKGFTPFPKK-KAVEAVVAD-TSDDAEDSE---EELNRGVRAGDYDY 1103

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSM IG+LTLEKVQELCA++D+L  EV++++++TPK LW+KDLD L+KQLDEQDK D Q
Sbjct: 1104 LLSMPIGTLTLEKVQELCAERDQLNGEVEDMRNATPKLLWLKDLDVLEKQLDEQDKIDIQ 1163

Query: 1801 AEVARKALKGKVMTEAGLKASRVVKNPRKNNTKKAN------NPPIEATVSSAVEIGNPS 1962
            AE AR+ +K KVM  AGLKA +    PRK N KKA+       P    +  ++    N +
Sbjct: 1164 AEEAREKIKKKVMNAAGLKAPK--PKPRK-NVKKASVVESTAEPMDRVSCFNSGNRSNVT 1220

Query: 1963 EVLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSA-AMDSE 2139
            EV+KPK RGG +KAPAK +                      AAYNL+SSPD SA AM++E
Sbjct: 1221 EVVKPKARGGSKKAPAKAKPIAVEDEEEEEDDEVLALKDRLAAYNLNSSPDHSAEAMETE 1280

Query: 2140 VP-ARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGENDDSDGDFEPEVE 2316
             P A+KK P+++AAAKK  L +  ++S+     +DE+++            D + EPEV 
Sbjct: 1281 APKAQKKAPTRKAAAKKKTLPSIADVSEG----EDEIEI----------SDDDESEPEVA 1326

Query: 2317 VVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQL--LNQKLITDTMKPVENA-GISPEK 2487
            V                              NKQ   + QKLIT  +KP EN    SPEK
Sbjct: 1327 VGGKKKGGRKPATAKAAPAAAKQPPKKRGPANKQAVGIGQKLITSILKPAENTDNSSPEK 1386

Query: 2488 KVRKMRASPFNKKSGSILGRIGTKDKDSSLMXXXXXXXXXXXXXXXXPDEVNEVXXXXXX 2667
            KVRKMRASPFN+KSG++LG    K+K S+L                  DEVNE       
Sbjct: 1387 KVRKMRASPFNEKSGAVLG----KNKGSTLQ--ENEDASPVSSLGSLEDEVNEA-VVAPK 1439

Query: 2668 XXXXXXXXXKYVLSDSES 2721
                      YV+SDS++
Sbjct: 1440 ARVTRGKKTTYVISDSDN 1457


>ref|XP_007220582.1| hypothetical protein PRUPE_ppa000202mg [Prunus persica]
            gi|462417044|gb|EMJ21781.1| hypothetical protein
            PRUPE_ppa000202mg [Prunus persica]
          Length = 1471

 Score = 1053 bits (2722), Expect = 0.0
 Identities = 554/865 (64%), Positives = 645/865 (74%), Gaps = 15/865 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+KNG+ L+FYSMPEYE+WKESL G A+GWSIKYYKGLGTSTSKEG++YF++L +HKKD
Sbjct: 576  ATHKNGKSLAFYSMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGRDYFQNLAMHKKD 635

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+W+DE+DG+AI+LAFSKKKIE RKNWLRQFEP  +LDQKEKLIKYSDFV+KELI FSMA
Sbjct: 636  FIWIDERDGEAIELAFSKKKIEERKNWLRQFEPSVHLDQKEKLIKYSDFVHKELIQFSMA 695

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STII
Sbjct: 696  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 755

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQDYVGSNNINLLQPNGQFGTR+ GGKDHASARYIYTRLSPITRFLFPKDDD LLDYL
Sbjct: 756  GMAQDYVGSNNINLLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYL 815

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEPT YVPIIPTVLVNGSEGIGTGWSSYIPNYN RDIVAN+R LLNGE M PMD
Sbjct: 816  NEDGQSIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNTRDIVANVRRLLNGEAMVPMD 875

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GF GTIEKT  KE+G SYTV G+IEE NETT+RI+ELP+RRWTQDYKEFLESI  G
Sbjct: 876  PWYRGFSGTIEKT-VKESGVSYTVCGVIEEGNETTVRISELPIRRWTQDYKEFLESISQG 934

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            NDK K+PFI+ + +H+D +TV   V + EENL+ A+ EGL+KKFKLTT+ISTSNMHLFDP
Sbjct: 935  NDKAKDPFIEGFTQHSDHSTVDIIVHLPEENLMAARQEGLLKKFKLTTSISTSNMHLFDP 994

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KGVIKKYDTPEQIL+EFFHLRLEFYEKR                  VRFIL VV GEIIV
Sbjct: 995  KGVIKKYDTPEQILEEFFHLRLEFYEKRKKVLLDNLEMELLKLENKVRFILAVVNGEIIV 1054

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGK-VRASDYE 1617
            SNR+RADLFLELQ+KGFTPFPKK K+ E  +AG   ED EE E+NSE   G   R SDYE
Sbjct: 1055 SNRRRADLFLELQQKGFTPFPKKTKAQEPEVAG-AIEDTEETEENSESASGNGARISDYE 1113

Query: 1618 YLLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDA 1797
            YL+SMAIG+LT+E+VQ LCAD+D++ NEV EL++STP+SLW+KDLDAL+ +L E +K++A
Sbjct: 1114 YLISMAIGTLTIERVQALCADRDKVNNEVAELRNSTPRSLWLKDLDALEMELGELEKSEA 1173

Query: 1798 QAEVARKALKGKVMTEAGLKASR-VVKNPRKNNTKKANNPPI-----EATVSSAVEIGNP 1959
             AE A+K  + +V      K SR   KNPRKNN KKANN        E + S   E+   
Sbjct: 1174 LAEEAKKKSRNQVKNAPAAKVSRPAPKNPRKNN-KKANNAEAAAESRETSSSFVFEMEKA 1232

Query: 1960 SEVLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSE 2139
             E++K K     +KAPA K++ ++                  AAYNLDSSP+ SA  ++E
Sbjct: 1233 PEIVKRKVGAVAKKAPAGKKQAKSAVVLSDDDDEVLELKDRLAAYNLDSSPENSAGKETE 1292

Query: 2140 V---PARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGENDDSDGDFEPE 2310
            V   P ++KEPSKRA              DDD + + E+   P   K     + G  +  
Sbjct: 1293 VPQEPVQRKEPSKRAMQ-----------IDDDEDFEVEIAAAPAAGKKGGRKAAGTTKAS 1341

Query: 2311 VEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQ-----LLNQKLITDTMKPVENAGI 2475
                                             NKQ        QKL+TD +KPVE +G+
Sbjct: 1342 --------------------KPPAAAKKRGAAANKQSQASSSSGQKLLTDMLKPVETSGV 1381

Query: 2476 SPEKKVRKMRASPFNKKSGSILGRI 2550
            SPE KVRKMRASPFNKKS S++G++
Sbjct: 1382 SPEPKVRKMRASPFNKKSSSVMGKV 1406


>ref|XP_002314046.2| DNA topoisomerase family protein [Populus trichocarpa]
            gi|550331162|gb|EEE88001.2| DNA topoisomerase family
            protein [Populus trichocarpa]
          Length = 1482

 Score = 1048 bits (2710), Expect = 0.0
 Identities = 553/881 (62%), Positives = 653/881 (74%), Gaps = 23/881 (2%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT++NG VLSFYSMPEYE WKESL G A+GWSIKYYKGLGTSTSKEGK+YFK+L  HKKD
Sbjct: 573  ATHRNGTVLSFYSMPEYEYWKESLSGNASGWSIKYYKGLGTSTSKEGKDYFKNLHKHKKD 632

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+W+DE DGDAI+LAFSKKKIEARKNWLRQ EPGT+LD  +K+IKYSDF+NKELILFSMA
Sbjct: 633  FLWMDELDGDAIELAFSKKKIEARKNWLRQHEPGTHLDHNQKIIKYSDFINKELILFSMA 692

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAK++QF+GYVSEHSAYHHGEQSL+ TII
Sbjct: 693  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLAGTII 752

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLLQPNGQFGTR  GGKDHASARYIYT+LSPITRFLFPKDDDGLL+YL
Sbjct: 753  GMAQDFVGSNNINLLQPNGQFGTRSVGGKDHASARYIYTQLSPITRFLFPKDDDGLLNYL 812

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            +EDGQ+IEPT Y+PIIPTVLVNG EGIGTGWS++IPNYNPRD+VANIR LLNGE MEPM+
Sbjct: 813  DEDGQTIEPTWYMPIIPTVLVNGCEGIGTGWSTFIPNYNPRDVVANIRRLLNGEMMEPMN 872

Query: 901  PWYKGFKGTIEKTATKEAG-ASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMT 1077
            PWY+GFKGTIEK A+KE G +SYTV+G+I E+NETTLRITELP+RRWT DYK FL S+  
Sbjct: 873  PWYRGFKGTIEKGASKEGGCSSYTVNGVINEVNETTLRITELPIRRWTDDYKAFLNSVTE 932

Query: 1078 GN-----DKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSN 1242
            G      +  K+PF+KD+R++ DD  VHFEV +SEEN+++AK EGL+KKFKLTTTISTSN
Sbjct: 933  GTRDENGNLPKDPFVKDFRKYGDDAAVHFEVQLSEENMLVAKQEGLLKKFKLTTTISTSN 992

Query: 1243 MHLFDPKGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVV 1422
            MHLFD  GVIKKYD PEQIL+ FFHLRLE+YE R                  VRFILGVV
Sbjct: 993  MHLFDSAGVIKKYDNPEQILENFFHLRLEYYETRKKVLLENLEFELLKLENKVRFILGVV 1052

Query: 1423 RGEIIVSNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVR 1602
            RGEIIV+NRKRADL LEL +KGF   PKK K++ A      T+D EE ED+ +V G  VR
Sbjct: 1053 RGEIIVNNRKRADLLLELHQKGFNAIPKKSKAVVAG----ATDDTEEAEDSPDVSG--VR 1106

Query: 1603 ASDYEYLLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQ 1782
            ASDY+YLLSMAIG+LTLE+VQ+LCAD+D+L  EVD L+ +TPK LW+KDL+AL+ QLD  
Sbjct: 1107 ASDYDYLLSMAIGTLTLERVQQLCADRDKLNGEVDSLRKTTPKVLWVKDLEALEMQLDML 1166

Query: 1783 DKNDAQAEVARKALKGK-VMTEAGLKASRVVKNPRKNNTKKANNPPIEATV-----SSAV 1944
            D+ DA+AE AR+ LKG     EAG K S+      + NTKKA N  +         S A+
Sbjct: 1167 DEYDAEAEEARRKLKGGGAKGEAGFKVSKQAPKYPRKNTKKAINEEVSVETTGTSSSFAI 1226

Query: 1945 EIG---NPSEVLKPKGRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPD 2115
            E     N + V+KPKGR G +KAPAK ++                      AY LDSSP+
Sbjct: 1227 ETASSENAAAVVKPKGRAGSKKAPAKMEKLSPVLDDFDEDDEIESLKDRLNAYRLDSSPE 1286

Query: 2116 QSAAMDSEVPARKKEPSKRAAAKKPPLSTFTEISD--DDGNMDD----EMQMIPEEKK-- 2271
            QSA M+++V    + P++R AA+K PL+  + ISD  D+ N+DD    E++ +PE KK  
Sbjct: 1287 QSADMETDV---LQVPARRGAARKKPLANVSVISDSEDEPNLDDDADVEVKALPETKKKG 1343

Query: 2272 GENDDSDGDFEPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTM 2451
            G    +  D   +                                   Q L QKL+T+ +
Sbjct: 1344 GRKAAAANDKAAKPPAATKRRGPAS--------------------QQSQGLGQKLLTEML 1383

Query: 2452 KPVENAGISPEKKVRKMRASPFNKKSGSILGRIGTKDKDSS 2574
            KP E AGISPEKKVRK+RASPFNKKSGS+LGRI  +D   S
Sbjct: 1384 KPAEGAGISPEKKVRKVRASPFNKKSGSVLGRIHKEDDTGS 1424


>ref|XP_004308680.1| PREDICTED: DNA topoisomerase 2-like [Fragaria vesca subsp. vesca]
          Length = 1469

 Score = 1043 bits (2697), Expect = 0.0
 Identities = 547/865 (63%), Positives = 648/865 (74%), Gaps = 10/865 (1%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+KNG+ L+FYSMPEYE+W+ESL G A+GW+IKYYKGLGTSTSKEG++YF++L++HKKD
Sbjct: 573  ATHKNGKELAFYSMPEYEAWRESLRGNASGWTIKYYKGLGTSTSKEGRDYFQNLDMHKKD 632

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            FVW+DE+DG+AI+LAFSKKKIE RKNWLRQFEPGT+LDQKEKL+KYSDFV+KELI FSMA
Sbjct: 633  FVWIDERDGEAIELAFSKKKIEERKNWLRQFEPGTHLDQKEKLVKYSDFVHKELIQFSMA 692

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAK+AQF+GYVSEHSAYHHGEQSL+STII
Sbjct: 693  DLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVAQFSGYVSEHSAYHHGEQSLASTII 752

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQDYVGSNNIN LQPNGQFGTR+ GGKDHASARYIYTRLSPITRFLFPKDDD LLDYL
Sbjct: 753  GMAQDYVGSNNINFLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFPKDDDRLLDYL 812

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEPT YVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNG+ M PMD
Sbjct: 813  NEDGQSIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGDEMVPMD 872

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GF G IEKT  KE G SYT  GIIEE+NETTLRI+ELP+RRWTQDYKEFLESI  G
Sbjct: 873  PWYRGFTGFIEKT-VKETGTSYTACGIIEEVNETTLRISELPIRRWTQDYKEFLESISQG 931

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            NDK K+PFI+ + +H+D +TV   V + EENL+ A+ EGL+KKF+LTT+I+T+NMHLFDP
Sbjct: 932  NDKAKDPFIEGFTQHSDHSTVEILVHLPEENLMAARKEGLLKKFRLTTSIATTNMHLFDP 991

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KGVIKKYDT EQIL+EFF LRLEFYEKR                  VRFILGVV GEIIV
Sbjct: 992  KGVIKKYDTAEQILEEFFPLRLEFYEKRKKVLLDNLELELLKMENKVRFILGVVNGEIIV 1051

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSE-VIGGKVRASDYE 1617
            SNRKRADLFLELQ+KGFTPFPKK KS+E  +AG  TED EE E+NSE VI   VR SDYE
Sbjct: 1052 SNRKRADLFLELQQKGFTPFPKKTKSVEPEVAG-ATEDTEETEENSETVISNGVRISDYE 1110

Query: 1618 YLLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDA 1797
            YL+SMAIG+LT+E+V+ L AD+D++  +V++L+ STPKSLW+KDLD L+ +L+E +K++A
Sbjct: 1111 YLISMAIGTLTIERVEALLADRDKVNEQVNDLRGSTPKSLWLKDLDVLEAELNELEKSEA 1170

Query: 1798 QAEVARKALKGKVMTEAGL-KASRVVKNPRKNNTKKANNPPI-----EATVSSAVEIGNP 1959
             A+ A++  +   +  A + K S+    PRK NTKK NN        E + SSA+EI  P
Sbjct: 1171 LADEAKRKSRNNQIKNAPVGKVSKQAPKPRK-NTKKVNNAEAIPESRETSSSSAMEIEKP 1229

Query: 1960 SEVLKPKG-RGGPRKAPAKKQEKRT-XXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMD 2133
             EV+K +G   G +KAPAKKQ K T                   AAYNLDSSPD+   + 
Sbjct: 1230 PEVMKRRGVAAGSKKAPAKKQVKSTVVLSDDDDDEEMLDLKDRLAAYNLDSSPDKETEVP 1289

Query: 2134 SEVPARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKKGENDDSDGDFEPEV 2313
             + PA+KKE SK+A  K        +  DDD + + E+   P   K       G  +   
Sbjct: 1290 LK-PAQKKEASKKATLK-------DDEDDDDDDFEVEIAAAPAAVKKGGRKPAGAAKAAA 1341

Query: 2314 EVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTMKP-VENAGISPEKK 2490
                                                  QKL+TD +KP  E++G+SP+ K
Sbjct: 1342 AA------------KPPVAAKKRGAAAKKDTQTSSSSGQKLLTDMLKPAAESSGVSPDPK 1389

Query: 2491 VRKMRASPFNKKSGSILGRIGTKDK 2565
            VRKMR SPFNKKSGS+L R+  +D+
Sbjct: 1390 VRKMRESPFNKKSGSVLSRVNLEDE 1414


>ref|XP_006838283.1| hypothetical protein AMTR_s00103p00101630 [Amborella trichopoda]
            gi|548840751|gb|ERN00852.1| hypothetical protein
            AMTR_s00103p00101630 [Amborella trichopoda]
          Length = 1505

 Score = 1025 bits (2650), Expect = 0.0
 Identities = 540/889 (60%), Positives = 644/889 (72%), Gaps = 34/889 (3%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            A NKNG+VLSFY++PEYESWKESLGG A GW+IKYYKGLGTSTS+EGKEYFK++  HKKD
Sbjct: 582  ARNKNGKVLSFYTLPEYESWKESLGGNARGWTIKYYKGLGTSTSQEGKEYFKEINKHKKD 641

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+WVD+QDGDAI+LAFSKKKIEARKNWLR FEPGTYLDQKEKLIKYSDFVNKELILFSMA
Sbjct: 642  FIWVDDQDGDAIELAFSKKKIEARKNWLRHFEPGTYLDQKEKLIKYSDFVNKELILFSMA 701

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNFV +AK+ QF+GYVSEHSAYHHGEQSL++TI+
Sbjct: 702  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVSQAKVVQFSGYVSEHSAYHHGEQSLAATIV 761

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VG+NNINLLQP GQFGTR++GGKD ASARYI+T LSPITRFLFPKDDD LLDY 
Sbjct: 762  GMAQDFVGTNNINLLQPLGQFGTRNRGGKDAASARYIFTCLSPITRFLFPKDDDVLLDYQ 821

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQ IEP  Y+PIIP VL+NGSEGIGTGWSSY+PNYNPRD+ AN++ LLNGE M PM+
Sbjct: 822  NEDGQCIEPNWYMPIIPLVLINGSEGIGTGWSSYVPNYNPRDVAANVKRLLNGESMLPME 881

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWYKGFKGTIEK+ATKE G  YTVSGI+EEINETTLRITELP+RRWT+DYK +LES+ TG
Sbjct: 882  PWYKGFKGTIEKSATKEGGVGYTVSGIVEEINETTLRITELPIRRWTEDYKVYLESLRTG 941

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            ++K KEPFI DY+EHN DT VHF+V++ EEN+ +++ EGLMK FKLTTTISTSNMHLF+ 
Sbjct: 942  SEKTKEPFIVDYKEHNTDTRVHFDVLLPEENMKISQQEGLMKMFKLTTTISTSNMHLFNA 1001

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KGVIKKYDTPEQIL+EFFHLRL++Y KR                   RFILGVV GEI+V
Sbjct: 1002 KGVIKKYDTPEQILEEFFHLRLDYYGKRKKVLLDNLELELLKLDNKARFILGVVNGEIVV 1061

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            S RKRADL LEL+ KGFTPFPKK K++EAA+AG T  D EE E++ EV    + ASDY+Y
Sbjct: 1062 SKRKRADLVLELRDKGFTPFPKKSKNVEAALAGATPVD-EEGEESPEVDDRGINASDYDY 1120

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSMAIG+LT+EKVQELCA+KD+L ++V EL+  TPK+LW+KDLDA   QLD +   +A+
Sbjct: 1121 LLSMAIGTLTIEKVQELCAEKDKLEHDVKELRGLTPKALWIKDLDAFLAQLDAEAVQEAK 1180

Query: 1801 AEVARKALKGKVMTEAGLKASRVVKNPRKNNTKKANNPPIEATVSSAVEIGNPSEVLKPK 1980
             +         ++++A     +V KNPRKN  K A   P E   + A +        KPK
Sbjct: 1181 DDEYEL---NNMVSDAAKIFRQVGKNPRKNTKKPA---PAEHVDTDASDTTTTEVAAKPK 1234

Query: 1981 GRGGPRKAPAKKQEKRTXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSEVPARKKE 2160
             R  P+KAP KK+                      A YN++SSP+  A M++++P R+ E
Sbjct: 1235 KRA-PKKAPTKKK----VDVEDMEDDLLLDLNARLAKYNIESSPEH-ADMETDLPERR-E 1287

Query: 2161 PSKRAAAKKPPLSTFTEISDDDGNMDDEMQMI----------------------PEEKKG 2274
            PSKRA +K  P   + +ISDD+    +E++                        P+EKK 
Sbjct: 1288 PSKRAVSK--PQQVYADISDDESEHLEEIEEEKEEEQEDEDPKPAKGKKKQAPKPKEKKK 1345

Query: 2275 ENDDSDGDF------------EPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQ 2418
             +  SD +F            E E                                  + 
Sbjct: 1346 MDGSSDEEFVISDEDLSVFDIETEDAPPKPKGRAKKPLSNKPKAPTGAAKKRGAASSKQP 1405

Query: 2419 LLNQKLITDTMKPVENAGISPEKKVRKMRASPFNKKSGSILGRIGTKDK 2565
            +LNQKLIT+ +KPV   G+SPEKKVRKMRASPFNKKSGS+LGRI  + K
Sbjct: 1406 ILNQKLITEVLKPV---GVSPEKKVRKMRASPFNKKSGSVLGRIERESK 1451


>ref|XP_004149716.1| PREDICTED: DNA topoisomerase 2-like [Cucumis sativus]
          Length = 1459

 Score = 1010 bits (2612), Expect = 0.0
 Identities = 539/883 (61%), Positives = 643/883 (72%), Gaps = 25/883 (2%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+KNG VLSFY+MPEYE+WKESL G A+GWSIKYYKGLGTSTSKEG+EYF+ L  HKKD
Sbjct: 537  ATHKNGTVLSFYTMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKD 596

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+W D+ DG+AI+LAFSKKKIE RKNWLRQFEPGT+LDQ  KLIKYSDFVNKELILFSMA
Sbjct: 597  FIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMA 656

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAK++QF+GYVSEHSAYHHGEQSL+STII
Sbjct: 657  DLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTII 716

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLL PNGQFGTR+ GGKDHAS+RYIYT+LS +TRFLFP+DDD LL+YL
Sbjct: 717  GMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDKLLNYL 776

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEPT Y+PIIPTVLVNGSEGIGTGWSSY+PNYNPRDI+ N+R +L GE M PMD
Sbjct: 777  NEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMD 836

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLES---I 1071
            PWY+GF GTIEKTATKE G +YTVSGIIEE+++TTLRI ELPVRRWT DYK+FL+S   +
Sbjct: 837  PWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRV 896

Query: 1072 MTGNDKIKE-----PFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTIST 1236
             + +DK KE     PFI+    H+DD  V  +V ++EEN+++A  EGL KKFKLTTT+ST
Sbjct: 897  ASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVST 956

Query: 1237 SNMHLFDPKGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILG 1416
            SNMHLFD  GVIKKYDTPEQIL+EFF LRLEFYEKR                  VRFIL 
Sbjct: 957  SNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILA 1016

Query: 1417 VVRGEIIVSNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGK 1596
            VV  EI VSNRK+ DLF ELQ KGFTPFPKK KS+E  IAG + E  +E E++ EV+ G+
Sbjct: 1017 VVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE-TDEAEESPEVVKGE 1075

Query: 1597 VRASDYEYLLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLD 1776
             R SDYEYLL++ IG+LT+EKVQELC+D+D+L  EVD+L+ +TPKSLW+ DLD L+K+LD
Sbjct: 1076 -RISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELD 1134

Query: 1777 EQDKNDAQAEVARKALKGKVMTEAGLKASRVVKNPRKNNTKKANNPPIEATV-----SSA 1941
            E D+NDAQ    RK  + K   +   K SR      +N+ K +N   +  ++     S+ 
Sbjct: 1135 EMDRNDAQTMELRKQQREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTT 1194

Query: 1942 VEIGNPSEVLKPKGRGGPRKAPAKKQEKRT--XXXXXXXXXXXXXXXXXXAAYNLDSSPD 2115
             E+ N + V+KPKG+  PRKAPAKK+ K                      AAY ++SSP+
Sbjct: 1195 TEVAN-NPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEDDEVLELKDRLAAYKIESSPE 1253

Query: 2116 QS--AAMDSEV------PARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKK 2271
             S  +AM++EV       A+KKEPSKRA AKK   +   +IS  D               
Sbjct: 1254 PSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISD--------------- 1298

Query: 2272 GENDDSDGDFEPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTM 2451
               DD+DGDFE + EV                                  L QKLIT  +
Sbjct: 1299 ---DDNDGDFEIK-EVDPPAAKKGGGRGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQML 1354

Query: 2452 KP-VENAGISPEKKVRKMRASPFNKKSGSILGR-IGTKDKDSS 2574
            +P  EN+GISPEKKVRK+RASPFNKKSGS+LGR IG +++D +
Sbjct: 1355 EPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDEN 1397


>ref|XP_004165384.1| PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-like [Cucumis
            sativus]
          Length = 1460

 Score = 1009 bits (2609), Expect = 0.0
 Identities = 537/883 (60%), Positives = 641/883 (72%), Gaps = 25/883 (2%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+KNG VLSFY+MPEYE+WKESL G A+GWSIKYYKGLGTSTSKEG+EYF+ L  HKKD
Sbjct: 537  ATHKNGTVLSFYTMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKD 596

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+W D+ DG+AI+LAFSKKKIE RKNWLRQFEPGT+LDQ  KLIKYSDFVNKELILFSMA
Sbjct: 597  FIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMA 656

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAK++QF+GYVSEHSAYHHGEQSL+STII
Sbjct: 657  DLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTII 716

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLL PNGQFGTR+ GGKDHAS+RYIYT+LS +TRFLFP+DDD LL+YL
Sbjct: 717  GMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDKLLNYL 776

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEPT Y+PIIPTVLVNGSEGIGTGWSSY+PNYNPRDI+ N+R +L GE M PMD
Sbjct: 777  NEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMD 836

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLES---I 1071
            PWY+GF GTIEKTATKE G +YTVSGIIEE+++TTLRI ELPVRRWT DYK+FL+S   +
Sbjct: 837  PWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRV 896

Query: 1072 MTGNDKIKE-----PFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTIST 1236
             + +DK KE     PFI+    H+DD  V  +V ++EEN+++A  EGL KKFKLTTT+ST
Sbjct: 897  ASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVST 956

Query: 1237 SNMHLFDPKGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILG 1416
            SNMHLFD  GVIKKYDTPEQIL+EFF LRLEFYEKR                  VRFIL 
Sbjct: 957  SNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILA 1016

Query: 1417 VVRGEIIVSNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGK 1596
            VV  EI VSNRK+ DLF ELQ KGFTPFPKK KS+E  IAG + E  +E E++ EV+ G+
Sbjct: 1017 VVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE-TDEAEESPEVVKGE 1075

Query: 1597 VRASDYEYLLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLD 1776
             R SDYEYLL++ IG+LT+EKVQELC+D+D+L  EVD+L+ +TPKSLW+ DLD L+K+LD
Sbjct: 1076 -RISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELD 1134

Query: 1777 EQDKNDAQAEVARKALKGKVMTEAGLKASRVVKNPRKNNTKKANNPPIEATV-----SSA 1941
            E D+NDAQ    RK  + K   +   K SR      +N+ K +N   +  ++     S+ 
Sbjct: 1135 EMDRNDAQTMELRKQQREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTT 1194

Query: 1942 VEIGNPSEVLKPKGRGGPRKAPAKKQEKRT--XXXXXXXXXXXXXXXXXXAAYNLDSSPD 2115
             E+ N + V+KPKG+  PRKAPAKK+ K                      AAY ++SSP+
Sbjct: 1195 TEVAN-NPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEDDEVLELKDRLAAYKIESSPE 1253

Query: 2116 QS--AAMDSEV------PARKKEPSKRAAAKKPPLSTFTEISDDDGNMDDEMQMIPEEKK 2271
             S  +AM++EV       A+KKEPSKRA AKK   +   +IS  D               
Sbjct: 1254 PSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISD--------------- 1298

Query: 2272 GENDDSDGDFEPEVEVVXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNKQLLNQKLITDTM 2451
               DD+DGDFE +                                     L QKLIT  +
Sbjct: 1299 ---DDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQML 1355

Query: 2452 KP-VENAGISPEKKVRKMRASPFNKKSGSILGR-IGTKDKDSS 2574
            +P  EN+GISPEKKVRK+RASPFNKKSGS+LGR IG +++D +
Sbjct: 1356 EPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDEN 1398


>ref|XP_007009329.1| Topoisomerase II isoform 3 [Theobroma cacao]
            gi|508726242|gb|EOY18139.1| Topoisomerase II isoform 3
            [Theobroma cacao]
          Length = 1244

 Score = 1007 bits (2604), Expect = 0.0
 Identities = 506/673 (75%), Positives = 575/673 (85%), Gaps = 5/673 (0%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+K   VLSFYSMPEYE WKESLGG A GWSIKYYKGLGTSTSKEGK+YFK+L+ H+K+
Sbjct: 570  ATHKTKGVLSFYSMPEYEFWKESLGGNAKGWSIKYYKGLGTSTSKEGKDYFKNLDKHRKE 629

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            FVW DEQDG+AI+LAFSKKKIEARKNWLRQFEPGT+LDQ +KLIKYS+F+NKELILFSMA
Sbjct: 630  FVWQDEQDGEAIELAFSKKKIEARKNWLRQFEPGTHLDQSQKLIKYSEFINKELILFSMA 689

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSM+DGLKPGQRKILFCSFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STI+
Sbjct: 690  DLQRSIPSMIDGLKPGQRKILFCSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTIV 749

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLL P GQFGTR+QGGKD ASARYI+T LSPITR+LFPKDDDGLLDYL
Sbjct: 750  GMAQDFVGSNNINLLNPGGQFGTRNQGGKDAASARYIFTNLSPITRYLFPKDDDGLLDYL 809

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEP  YVPIIP VLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LLNGE MEPM 
Sbjct: 810  NEDGQSIEPIWYVPIIPMVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLNGEQMEPMH 869

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GFKG IEKTA+KEAG +YT++GIIEE++ETTLRITELPVRRWTQDY+EFLESI+TG
Sbjct: 870  PWYRGFKGNIEKTASKEAGVTYTITGIIEEVDETTLRITELPVRRWTQDYREFLESIITG 929

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            ND    PFIK++R+++DDTTV FEVI++EEN+++AK EGL+KKFKLTTTISTSNMHLFD 
Sbjct: 930  ND----PFIKEFRQYSDDTTVEFEVILTEENMMVAKQEGLLKKFKLTTTISTSNMHLFDS 985

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KG+IKKYDTPEQIL+EFFHLR EFYEKR                  VRFILGVV+GEIIV
Sbjct: 986  KGMIKKYDTPEQILEEFFHLRFEFYEKRKKLLLDNLEMELLKMENKVRFILGVVKGEIIV 1045

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVTTEDAEENEDNSEVIGGKVRASDYEY 1620
            +NRKRADLFLELQ KGFTPFPKK K++E A+AG  T+D EE E+NSEV    ++ASDY+Y
Sbjct: 1046 NNRKRADLFLELQTKGFTPFPKKAKTVEVAVAG-ATDDTEETEENSEVSAKGLQASDYDY 1104

Query: 1621 LLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKNDAQ 1800
            LLSMAIGSLTLEKVQELCAD+D+L  EV++L+ +TPKSLW+KDLD L+ QLDEQDK  AQ
Sbjct: 1105 LLSMAIGSLTLEKVQELCADRDKLQQEVEDLRKATPKSLWLKDLDNLEIQLDEQDK-AAQ 1163

Query: 1801 AEVARKALKGKVMTEAGLKASR-VVKNPRKNNTKKANNPPIEATV----SSAVEIGNPSE 1965
            AE A K +KG+   EAG +A R   K PRK N K+ N   +  T     SSA+E      
Sbjct: 1164 AEEAAKLVKGR--GEAGKRAQRQAPKIPRKINKKEKNAETVTETTDISSSSAMETETAPA 1221

Query: 1966 VLKPKGRGGPRKA 2004
             +KPKGRGG RKA
Sbjct: 1222 AVKPKGRGGSRKA 1234


>emb|CAJ44361.1| putative DNA topoisomerase II [Malus domestica]
          Length = 1467

 Score = 1004 bits (2597), Expect = 0.0
 Identities = 541/899 (60%), Positives = 639/899 (71%), Gaps = 44/899 (4%)
 Frame = +1

Query: 1    ATNKNGRVLSFYSMPEYESWKESLGGTANGWSIKYYKGLGTSTSKEGKEYFKDLELHKKD 180
            AT+KNG  L+FYSMPEYE+WKESL G A+GWSIKYYKGLGTSTSKEG++YF++L  HKKD
Sbjct: 540  ATHKNGNTLAFYSMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGRDYFQNLVQHKKD 599

Query: 181  FVWVDEQDGDAIDLAFSKKKIEARKNWLRQFEPGTYLDQKEKLIKYSDFVNKELILFSMA 360
            F+W+DE+DG+AI+LAFSKKKIE RKNWLRQFEPG +LDQKEKLIKYSDFV+KELI FSMA
Sbjct: 600  FIWIDERDGEAIELAFSKKKIEERKNWLRQFEPGVHLDQKEKLIKYSDFVHKELIQFSMA 659

Query: 361  DLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKIAQFAGYVSEHSAYHHGEQSLSSTII 540
            DLQRSIPSMVDGLKPGQRKILF SFKRNFVKEAK+AQF+GYVSEHSAYHHGEQSL+STII
Sbjct: 660  DLQRSIPSMVDGLKPGQRKILFSSFKRNFVKEAKVAQFSGYVSEHSAYHHGEQSLASTII 719

Query: 541  GMAQDYVGSNNINLLQPNGQFGTRHQGGKDHASARYIYTRLSPITRFLFPKDDDGLLDYL 720
            GMAQD+VGSNNINLLQPNGQFGTR+ GGKDHASARYIYTRLSPITRFLF KDDD LLDYL
Sbjct: 720  GMAQDFVGSNNINLLQPNGQFGTRNLGGKDHASARYIYTRLSPITRFLFSKDDDRLLDYL 779

Query: 721  NEDGQSIEPTCYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANIRCLLNGEPMEPMD 900
            NEDGQSIEPT YVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVAN+R LL+G+ M PMD
Sbjct: 780  NEDGQSIEPTWYVPIIPTVLVNGSEGIGTGWSSYIPNYNPRDIVANVRRLLDGDAMVPMD 839

Query: 901  PWYKGFKGTIEKTATKEAGASYTVSGIIEEINETTLRITELPVRRWTQDYKEFLESIMTG 1080
            PWY+GF GTIEKT  KE+G SYT  GIIEE++ET+LRI+ELP+RRWTQDYKEFLESI  G
Sbjct: 840  PWYRGFTGTIEKT-VKESGVSYTACGIIEEVSETSLRISELPIRRWTQDYKEFLESISEG 898

Query: 1081 NDKIKEPFIKDYREHNDDTTVHFEVIMSEENLVMAKLEGLMKKFKLTTTISTSNMHLFDP 1260
            NDK K+PFI+ + +H+D +TV   V + EE L+ AK EGL+KKFKLTT+ISTSNMHLFD 
Sbjct: 899  NDKAKDPFIEGFTQHSDHSTVDIIVHLREEKLMAAKQEGLLKKFKLTTSISTSNMHLFDR 958

Query: 1261 KGVIKKYDTPEQILQEFFHLRLEFYEKRXXXXXXXXXXXXXXXXXXVRFILGVVRGEIIV 1440
            KGVIKKYDTPEQIL++FFHLRLEFYEKR                  VRFILGVV GEIIV
Sbjct: 959  KGVIKKYDTPEQILEDFFHLRLEFYEKRKKVLLEDLELELLKLENKVRFILGVVNGEIIV 1018

Query: 1441 SNRKRADLFLELQKKGFTPFPKKIKSIEAAIAGVT--TEDAEENEDNSEVIGGKVRASDY 1614
            SNRKRADLFLELQ+KGFTPFPKK K++E  +AG T  TEDAEEN + +   G ++  SDY
Sbjct: 1019 SNRKRADLFLELQQKGFTPFPKKTKALEPEVAGATENTEDAEENSEAAIEKGARI--SDY 1076

Query: 1615 EYLLSMAIGSLTLEKVQELCADKDRLTNEVDELKSSTPKSLWMKDLDALDKQLDEQDKND 1794
            EYL+SMAIG+LT+E+VQ L AD+D+   EVDEL+ STP+SLW+KDLDAL+ +LD  +K++
Sbjct: 1077 EYLISMAIGTLTIERVQALLADRDKANAEVDELRKSTPRSLWLKDLDALEMELDVLEKSE 1136

Query: 1795 AQAEVARKALKGKVMTEAGLKASRVVKNPRKNNTKKANNPPIEATV-------------- 1932
            A AE A+K  + +V      KAS+    PRK NTKKANN    ++V              
Sbjct: 1137 ALAEEAKKKARTQVKNVPASKASKQAPKPRK-NTKKANNAEAASSVMEIARRYYFIIEFS 1195

Query: 1933 -------SSAVEIGNPSEVLKPKGRGGPRKAP---------------------AKKQEKR 2028
                   SSA  +   S   +   R G +++                        +Q K 
Sbjct: 1196 DCFTHIISSACFVRERSRGSEKDRRSGSKESSCCQEVEQIRCTQEAGTYIFMFVMQQVKS 1255

Query: 2029 TXXXXXXXXXXXXXXXXXXAAYNLDSSPDQSAAMDSEVPARKKEPSKRAAAKKPPLSTFT 2208
            +                  AAYNLDSSP+ SA  D  V  +KKE +K+   +        
Sbjct: 1256 SAVLSDDDDDEVLELKERLAAYNLDSSPENSAGNDKVV--QKKEANKKVVMQ-------- 1305

Query: 2209 EISDDDGNMDDEMQMIPEEKKGENDDSDGDFEPEVEVVXXXXXXXXXXXXXXXXXXXXXX 2388
               D D + ++E+   P   KG    + G  +P+V                         
Sbjct: 1306 --MDSDDDFEEEIAAAP---KGGRKKAAG--KPKVAA------------SKPPAAAKKRG 1346

Query: 2389 XXXXXXMNKQLLNQKLITDTMKPVENAGISPEKKVRKMRASPFNKKSGSILGRIGTKDK 2565
                    +    QKL+TD +KP E++  SPE KVRKMRASPFNKKSGS++GR+G  D+
Sbjct: 1347 TAANKKQPQTSSGQKLLTDMLKPAESSRASPEPKVRKMRASPFNKKSGSVMGRVGLADE 1405