BLASTX 2.2.25 [Feb-01-2011]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Aconitum21_contig00007532
         (3085 letters)

Database: ./nr 
           23,641,837 sequences; 8,123,359,852 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|XP_002283993.1| PREDICTED: zinc-metallopeptidase, peroxisoma...  1529   0.0  
ref|XP_002532073.1| Insulin-degrading enzyme, putative [Ricinus ...  1453   0.0  
ref|XP_002283970.1| PREDICTED: zinc-metallopeptidase, peroxisoma...  1447   0.0  
ref|XP_002308028.1| predicted protein [Populus trichocarpa] gi|2...  1439   0.0  
ref|NP_001233926.1| insulin degrading enzyme [Solanum lycopersic...  1420   0.0  

>ref|XP_002283993.1| PREDICTED: zinc-metallopeptidase, peroxisomal [Vitis vinifera]
            gi|297739661|emb|CBI29843.3| unnamed protein product
            [Vitis vinifera]
          Length = 965

 Score = 1529 bits (3958), Expect = 0.0
 Identities = 729/965 (75%), Positives = 840/965 (87%)
 Frame = +1

Query: 43   VGKSETEIIKPRTDKRDYRRIXXXXXXXXXXXXDPETDKAAASMNVGVGSFCDPAGLEGL 222
            +G++  EI+KPRTD R+YRRI            DP+TDKAAASM+V VGSFCDP G  GL
Sbjct: 1    MGEAAAEIVKPRTDTREYRRIVLRNSLEVLLISDPDTDKAAASMSVSVGSFCDPEGFPGL 60

Query: 223  AHFLEHMLFYASEKYPLENSYSKYITEHGGSTNAYTSSEHTNYYFDVNTNCFEEALDRFA 402
            AHFLEHMLFYASEKYPLE+SYSKYI EHGGSTNA+TSSEHTNYYFDVN++CFEEALDRFA
Sbjct: 61   AHFLEHMLFYASEKYPLEDSYSKYIIEHGGSTNAFTSSEHTNYYFDVNSDCFEEALDRFA 120

Query: 403  QFFLKPLMSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSDKAHPYHKFSTGSWDTL 582
            QFF+KPLMS+DATTREIKAVDSENQKNLLSD WRM QLQKH+S + HPYHKFSTG+WDTL
Sbjct: 121  QFFVKPLMSADATTREIKAVDSENQKNLLSDAWRMCQLQKHISAEGHPYHKFSTGNWDTL 180

Query: 583  EVRPKERGLDTRQKLIEFYENNYSANLMYLVVYGNKTLDEMQNLVCHEFGEVRNTDRSCF 762
            EV+PKE+GLDTR +LI+FYE +YSANLM+LVVY  ++LD++Q+LV H+F E++N DRS F
Sbjct: 181  EVKPKEKGLDTRHELIKFYEEHYSANLMHLVVYTKESLDKIQSLVEHKFQEIQNKDRSNF 240

Query: 763  QFPGQPCLPEHLQILVKTVPVKQGHRLRVIWPITPSIRHYKKAPCRYLGHLIGHEGEGSL 942
            Q PGQPC  EHLQILVKTVP+KQGH+LRVIWPITPSI +YK+ PCRYLGHLIGHEGEGSL
Sbjct: 241  QIPGQPCTSEHLQILVKTVPIKQGHKLRVIWPITPSIHNYKEGPCRYLGHLIGHEGEGSL 300

Query: 943  FYIFKQLGWATSLSAGEGDWTSEFSFFKVSIDLTDAGHDHIEDIVGLLFKYVLLLQKSGV 1122
            FYI K LGWATSLSAGEGDWT EFSFFKV IDLT+AGH+H++DIVGLLFKY+ LLQ++GV
Sbjct: 301  FYILKTLGWATSLSAGEGDWTCEFSFFKVVIDLTEAGHEHMQDIVGLLFKYISLLQQTGV 360

Query: 1123 KKWIFDELAAICETVFHYQDKVPPIDYAVHISSNMQIYPPKDWLVASSLPSEFSPDTIQM 1302
             KWIFDEL+AICETVFHYQDK+PPIDY V++SSNM++YPPKDWLV SSLPS+FSPD IQ 
Sbjct: 361  CKWIFDELSAICETVFHYQDKIPPIDYVVNVSSNMELYPPKDWLVGSSLPSKFSPDVIQK 420

Query: 1303 ILDELSLNNVRIFWESQKFKGHTDMVEPWYGTEYSVQKISSSMIQQWIEKAPDEHLHLPT 1482
            +LDEL+ NNVRIFWES+ F+GHTDMVEPWYGT YS++KI+SSMIQQW+  AP+EHLHLP+
Sbjct: 421  VLDELAPNNVRIFWESKNFEGHTDMVEPWYGTAYSIEKITSSMIQQWMLAAPNEHLHLPS 480

Query: 1483 PNVFIPTDLSLKEMQDKAKFPVLLRKSSYSRLWYKPNTMFCTPKAYVRIDFHCPYTSHSP 1662
            PNVFIPTDLSLK++Q+KAKFPVLLRKSSYS LWYKP+TMF TPKAYV+IDF+CP+ S SP
Sbjct: 481  PNVFIPTDLSLKDVQEKAKFPVLLRKSSYSTLWYKPDTMFSTPKAYVKIDFNCPFASSSP 540

Query: 1663 EAVVLTDIFTRLLMDYLNEYAYDAQVAGLYYAINHADTGFQVIVVGYNHKMRILVDTVLE 1842
            EA VLTDIFTRLLMDYLNEYAY AQVAGLYY INH D+GFQV V GYNHK+RIL++TV+E
Sbjct: 541  EADVLTDIFTRLLMDYLNEYAYYAQVAGLYYGINHTDSGFQVAVTGYNHKLRILLETVVE 600

Query: 1843 KIAEFKVKRDRFYVIKETVTKQYQNLKFQQPYQQAMYYCSLILEDHSWPWTXXXXXXXXX 2022
            KIA FKVK DRF VIKE VTK+YQN KFQQPYQQAMYYCSLIL+D++WPW          
Sbjct: 601  KIANFKVKPDRFLVIKEMVTKEYQNFKFQQPYQQAMYYCSLILQDNTWPWMDGLEVIPHL 660

Query: 2023 XXXXXXKFSPLLLSKAFLDCYVAGNMEPKEAESMIFHIEDIFFNGPKHICRALLPSEHLT 2202
                  KF P+LLS+AFLDCY+AGN+EPKEAESMI HIEDIF++GP  I + L PS++LT
Sbjct: 661  EADDLAKFVPMLLSRAFLDCYIAGNIEPKEAESMIHHIEDIFYSGPHPISQPLFPSQYLT 720

Query: 2203 NRIVKLEKGTCYFYKCEVLNKDDENSALVHYIQVHQDDFMMNVKVQLFALIAKQAAFHQL 2382
            NR++KL++G  YFY  E LN  DENSALVHYIQVH+DDF+ NVK+QLFALIAKQ AFHQL
Sbjct: 721  NRVIKLDRGMSYFYPAEGLNPSDENSALVHYIQVHRDDFLPNVKLQLFALIAKQRAFHQL 780

Query: 2383 RSVEQLGYITVLMQRNDSGIRGLQFIIQSTVKDPGQINTRVEAFLKEFESIFYALSDDEF 2562
            RSVEQLGYITVLMQRNDSGIRG+QFIIQSTVK PG I++RV  FLK FES  YA+S+DEF
Sbjct: 781  RSVEQLGYITVLMQRNDSGIRGVQFIIQSTVKGPGHIDSRVVEFLKMFESKLYAMSEDEF 840

Query: 2563 RSNVDALIDMKLEKHKNLREESAFYWREIADGTLKFDRRDAEVVALKSLKKEDLTNFFDE 2742
            +SNV+ALIDMKLEKHKNLREES FYWREI DGTLKFDRR+AEV ALK L +++L +FF+E
Sbjct: 841  KSNVNALIDMKLEKHKNLREESGFYWREIYDGTLKFDRREAEVAALKKLTQKELIDFFNE 900

Query: 2743 HIKVSAPQKRTLSIQVYGSSHSSEYNASKSEAPQPESVYIEDIFSFRRSQSLYGSFKGGL 2922
            HIKV APQK+TLS++VYG  H+SEY   K EA QP+ V I+DIF FR+SQ LYGSFKGGL
Sbjct: 901  HIKVGAPQKKTLSVRVYGGLHTSEYADEKKEANQPKQVKIDDIFKFRKSQPLYGSFKGGL 960

Query: 2923 GHMKL 2937
            G +KL
Sbjct: 961  GQVKL 965


>ref|XP_002532073.1| Insulin-degrading enzyme, putative [Ricinus communis]
            gi|223528255|gb|EEF30307.1| Insulin-degrading enzyme,
            putative [Ricinus communis]
          Length = 967

 Score = 1453 bits (3761), Expect = 0.0
 Identities = 694/967 (71%), Positives = 808/967 (83%)
 Frame = +1

Query: 37   MAVGKSETEIIKPRTDKRDYRRIXXXXXXXXXXXXDPETDKAAASMNVGVGSFCDPAGLE 216
            MAVGK E EI+K RTDKR+YRRI            DPETDK AASM+V VG F DPAGLE
Sbjct: 1    MAVGKEEVEIVKARTDKREYRRIVLRNSLEVLLISDPETDKCAASMDVSVGFFSDPAGLE 60

Query: 217  GLAHFLEHMLFYASEKYPLENSYSKYITEHGGSTNAYTSSEHTNYYFDVNTNCFEEALDR 396
            GLAHFLEHMLFYASEKYPLE+SYSKYITEHGGSTNA+TSSE TNYYFDVNT+CFE+ALDR
Sbjct: 61   GLAHFLEHMLFYASEKYPLEDSYSKYITEHGGSTNAFTSSEFTNYYFDVNTDCFEDALDR 120

Query: 397  FAQFFLKPLMSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSDKAHPYHKFSTGSWD 576
            FAQFF+KPLMS+DAT REIKAVDSENQKNLLSD WRM QLQKHLSD+ HPYHKF TG+WD
Sbjct: 121  FAQFFIKPLMSADATMREIKAVDSENQKNLLSDAWRMGQLQKHLSDEGHPYHKFGTGNWD 180

Query: 577  TLEVRPKERGLDTRQKLIEFYENNYSANLMYLVVYGNKTLDEMQNLVCHEFGEVRNTDRS 756
            TLEVRPK +GLDTR +LI+FYE NYSAN M+LV+Y  ++LD++Q L+  +F  +RN DRS
Sbjct: 181  TLEVRPKAKGLDTRNELIKFYEENYSANRMHLVIYAKESLDKLQILIEDKFQHIRNKDRS 240

Query: 757  CFQFPGQPCLPEHLQILVKTVPVKQGHRLRVIWPITPSIRHYKKAPCRYLGHLIGHEGEG 936
            C  FPGQPC  EHLQILVK VP+KQGHRL++IWPITP I HYK+ PCRYLGHLIGHEGEG
Sbjct: 241  CLSFPGQPCSSEHLQILVKAVPIKQGHRLKIIWPITPEILHYKEGPCRYLGHLIGHEGEG 300

Query: 937  SLFYIFKQLGWATSLSAGEGDWTSEFSFFKVSIDLTDAGHDHIEDIVGLLFKYVLLLQKS 1116
            SLFY+ K LGWATSLSAGEGDWT EFSFFKV IDLTDAGH+H++DI+GLLFKY+ LLQ+S
Sbjct: 301  SLFYVLKTLGWATSLSAGEGDWTMEFSFFKVGIDLTDAGHEHMQDIIGLLFKYIHLLQQS 360

Query: 1117 GVKKWIFDELAAICETVFHYQDKVPPIDYAVHISSNMQIYPPKDWLVASSLPSEFSPDTI 1296
            GV +WIF+ELAA+CET FHYQDK+PPIDY V I+ NM IYPPKDWLV SSLPS FSPD I
Sbjct: 361  GVSEWIFNELAAVCETSFHYQDKIPPIDYVVTIACNMNIYPPKDWLVGSSLPSNFSPDII 420

Query: 1297 QMILDELSLNNVRIFWESQKFKGHTDMVEPWYGTEYSVQKISSSMIQQWIEKAPDEHLHL 1476
            QM+L +LS N+VRIFWES+ F+G T+ VEPWYGT YSV+KI S +IQ+W+  APDE+LHL
Sbjct: 421  QMVLHQLSPNSVRIFWESKNFEGQTEKVEPWYGTAYSVEKIDSLVIQEWMLSAPDENLHL 480

Query: 1477 PTPNVFIPTDLSLKEMQDKAKFPVLLRKSSYSRLWYKPNTMFCTPKAYVRIDFHCPYTSH 1656
            P PNVFIPTDLSLK  Q+K   PVLLRKSSYS LWYKP+TMF TPKAYV+IDF CP+   
Sbjct: 481  PAPNVFIPTDLSLKSAQEKVILPVLLRKSSYSSLWYKPDTMFNTPKAYVKIDFSCPHAGS 540

Query: 1657 SPEAVVLTDIFTRLLMDYLNEYAYDAQVAGLYYAINHADTGFQVIVVGYNHKMRILVDTV 1836
            SPEA VLTDIF RLLMDYLNEYAY AQVAGLYY I   D+GFQV +VGYNHK++IL++TV
Sbjct: 541  SPEADVLTDIFARLLMDYLNEYAYYAQVAGLYYGITKTDSGFQVTLVGYNHKLKILLETV 600

Query: 1837 LEKIAEFKVKRDRFYVIKETVTKQYQNLKFQQPYQQAMYYCSLILEDHSWPWTXXXXXXX 2016
            +EKIA+FKV  DRF VIKE V K+Y+N KFQQPYQQA+YY SLIL++ +WPW        
Sbjct: 601  IEKIAKFKVNPDRFSVIKEMVIKKYKNFKFQQPYQQAIYYSSLILQNQAWPWMEELEVLP 660

Query: 2017 XXXXXXXXKFSPLLLSKAFLDCYVAGNMEPKEAESMIFHIEDIFFNGPKHICRALLPSEH 2196
                    KF P++LS++FL+CY+AGN+E  EAES+I HIE++FF G   IC+ L PS+H
Sbjct: 661  HLVAEDLAKFVPIMLSRSFLECYIAGNIESIEAESIIEHIENVFFKGQNPICQPLFPSQH 720

Query: 2197 LTNRIVKLEKGTCYFYKCEVLNKDDENSALVHYIQVHQDDFMMNVKVQLFALIAKQAAFH 2376
            LTNR++KL +G  YFY  E LN  DENSALVHYIQVHQDDF++NVK+QLFALIAKQ AFH
Sbjct: 721  LTNRVMKLGRGKSYFYAIEGLNPSDENSALVHYIQVHQDDFLLNVKLQLFALIAKQPAFH 780

Query: 2377 QLRSVEQLGYITVLMQRNDSGIRGLQFIIQSTVKDPGQINTRVEAFLKEFESIFYALSDD 2556
            QLRSVEQLGYITVLM RNDSGIRG+ FIIQSTVK P  I+ RVEAFLK FE+  Y +++D
Sbjct: 781  QLRSVEQLGYITVLMPRNDSGIRGVHFIIQSTVKGPVHIDLRVEAFLKSFETKLYEMTND 840

Query: 2557 EFRSNVDALIDMKLEKHKNLREESAFYWREIADGTLKFDRRDAEVVALKSLKKEDLTNFF 2736
            EF++NV++LIDMKLEKHKNL EES FYWREIADGTLKFDRRD+EV AL+ L +++  +FF
Sbjct: 841  EFKNNVNSLIDMKLEKHKNLGEESGFYWREIADGTLKFDRRDSEVAALRQLTQQEFVDFF 900

Query: 2737 DEHIKVSAPQKRTLSIQVYGSSHSSEYNASKSEAPQPESVYIEDIFSFRRSQSLYGSFKG 2916
            +E+IKV AP +RTLSI+VYG+SHS+EY + KSE+  P S+ I+DIFSFRR+QSLYGS +G
Sbjct: 901  NENIKVGAPGRRTLSIRVYGASHSAEYTSDKSESLLPNSIQIDDIFSFRRTQSLYGSCRG 960

Query: 2917 GLGHMKL 2937
            G GHMKL
Sbjct: 961  GFGHMKL 967


>ref|XP_002283970.1| PREDICTED: zinc-metallopeptidase, peroxisomal [Vitis vinifera]
            gi|297739662|emb|CBI29844.3| unnamed protein product
            [Vitis vinifera]
          Length = 965

 Score = 1447 bits (3745), Expect = 0.0
 Identities = 692/965 (71%), Positives = 819/965 (84%)
 Frame = +1

Query: 43   VGKSETEIIKPRTDKRDYRRIXXXXXXXXXXXXDPETDKAAASMNVGVGSFCDPAGLEGL 222
            +G++  EI+KPRTD R+YRRI            DP+TDKAAASM+V VGSF DP G  GL
Sbjct: 1    MGEAAVEIVKPRTDTREYRRIVLRNSLEALLISDPDTDKAAASMSVSVGSFSDPEGFPGL 60

Query: 223  AHFLEHMLFYASEKYPLENSYSKYITEHGGSTNAYTSSEHTNYYFDVNTNCFEEALDRFA 402
            AHFLEHMLFYASEKYPLE+SYSKYITEHGGSTNA+T+SEHTNY+FDVNT+CFEEALDRFA
Sbjct: 61   AHFLEHMLFYASEKYPLEDSYSKYITEHGGSTNAFTASEHTNYFFDVNTDCFEEALDRFA 120

Query: 403  QFFLKPLMSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSDKAHPYHKFSTGSWDTL 582
            QFF+KPLMS+DATTREIKAVDSEN+KNLLSD WRM QLQKH+S + HPYHKFSTG+ DTL
Sbjct: 121  QFFVKPLMSADATTREIKAVDSENKKNLLSDAWRMDQLQKHVSAEGHPYHKFSTGNRDTL 180

Query: 583  EVRPKERGLDTRQKLIEFYENNYSANLMYLVVYGNKTLDEMQNLVCHEFGEVRNTDRSCF 762
            EV+PKE+GLDTR +LI+FYE +YSANLM+LVVY  ++LD++Q+LV H+F E++N DR  F
Sbjct: 181  EVKPKEKGLDTRHELIKFYEEHYSANLMHLVVYTKESLDKIQSLVEHKFQEIQNKDRINF 240

Query: 763  QFPGQPCLPEHLQILVKTVPVKQGHRLRVIWPITPSIRHYKKAPCRYLGHLIGHEGEGSL 942
               GQPC  EHLQILVKTVP+KQGH+L V+WPITPSI +YK+ PCRYLGHLIGHEG+GSL
Sbjct: 241  HICGQPCTSEHLQILVKTVPIKQGHKLIVVWPITPSIHNYKEGPCRYLGHLIGHEGKGSL 300

Query: 943  FYIFKQLGWATSLSAGEGDWTSEFSFFKVSIDLTDAGHDHIEDIVGLLFKYVLLLQKSGV 1122
            FYI K LGWATSLSA E DWT EFSFF+V IDLTDAGH+H++DIVGLLFKY+ LLQ++GV
Sbjct: 301  FYILKTLGWATSLSAWEEDWTCEFSFFEVVIDLTDAGHEHMQDIVGLLFKYISLLQQTGV 360

Query: 1123 KKWIFDELAAICETVFHYQDKVPPIDYAVHISSNMQIYPPKDWLVASSLPSEFSPDTIQM 1302
             KWIFDEL+AICET+FHYQDK+P IDY V++SSNM++YPPKDWLV SSLPS+FSPD IQ 
Sbjct: 361  CKWIFDELSAICETMFHYQDKIPSIDYVVNVSSNMELYPPKDWLVGSSLPSKFSPDVIQK 420

Query: 1303 ILDELSLNNVRIFWESQKFKGHTDMVEPWYGTEYSVQKISSSMIQQWIEKAPDEHLHLPT 1482
            +LDEL+ NNVRIFWES+ F+GHTDMVEPWYGT +S++KI+ SMIQQW+  AP EHLHLP 
Sbjct: 421  VLDELAPNNVRIFWESKNFEGHTDMVEPWYGTAFSIEKITVSMIQQWMLAAPTEHLHLPD 480

Query: 1483 PNVFIPTDLSLKEMQDKAKFPVLLRKSSYSRLWYKPNTMFCTPKAYVRIDFHCPYTSHSP 1662
            PN FIPTDLSLK +Q+KAKFPVLLRKSSYS LWYKP+TMF TPKAYV+IDF+CP+ S SP
Sbjct: 481  PNDFIPTDLSLKNVQEKAKFPVLLRKSSYSTLWYKPDTMFSTPKAYVKIDFNCPFASSSP 540

Query: 1663 EAVVLTDIFTRLLMDYLNEYAYDAQVAGLYYAINHADTGFQVIVVGYNHKMRILVDTVLE 1842
            EA VLTDIFTRLLMDYLNE AY A+VAGLYY +++ D+GFQV + GYNHK+RIL++TV++
Sbjct: 541  EADVLTDIFTRLLMDYLNEDAYYAEVAGLYYCLSNTDSGFQVAMAGYNHKLRILLETVVK 600

Query: 1843 KIAEFKVKRDRFYVIKETVTKQYQNLKFQQPYQQAMYYCSLILEDHSWPWTXXXXXXXXX 2022
            KIA FKVK DRF VIKE VTK YQN+KFQQPYQQAM Y SLIL D++WPW          
Sbjct: 601  KIANFKVKPDRFLVIKELVTKGYQNVKFQQPYQQAMCYRSLILHDNTWPWMDGLEVIPHL 660

Query: 2023 XXXXXXKFSPLLLSKAFLDCYVAGNMEPKEAESMIFHIEDIFFNGPKHICRALLPSEHLT 2202
                  KF P+LLS+AFL+CY+AGN+EPKEAE+MI HIEDIF++GP+ IC+ L PS++LT
Sbjct: 661  EADDLAKFVPMLLSRAFLECYIAGNIEPKEAEAMIHHIEDIFYSGPRPICQPLFPSQYLT 720

Query: 2203 NRIVKLEKGTCYFYKCEVLNKDDENSALVHYIQVHQDDFMMNVKVQLFALIAKQAAFHQL 2382
            NR++KL++G  YFY  E LN  DENSALVHYIQVH+DDF+ NVK+QLFALIAKQ AFHQL
Sbjct: 721  NRVIKLDRGMSYFYPAEGLNPSDENSALVHYIQVHRDDFLPNVKLQLFALIAKQQAFHQL 780

Query: 2383 RSVEQLGYITVLMQRNDSGIRGLQFIIQSTVKDPGQINTRVEAFLKEFESIFYALSDDEF 2562
            RSVEQLGYIT LM RNDSGI G+QF+IQSTVK PG I++R+E FLK FE   YA+S+DEF
Sbjct: 781  RSVEQLGYITELMLRNDSGIHGVQFMIQSTVKGPGHIDSRIEEFLKMFEFKLYAMSEDEF 840

Query: 2563 RSNVDALIDMKLEKHKNLREESAFYWREIADGTLKFDRRDAEVVALKSLKKEDLTNFFDE 2742
            +SNV+ L+DMKLEK+KNL EES FYW+EI DGTLKFDR +AEV ALK L +++L +FF+E
Sbjct: 841  KSNVNTLVDMKLEKYKNLWEESGFYWQEIYDGTLKFDRTEAEVAALKKLTQKELIDFFNE 900

Query: 2743 HIKVSAPQKRTLSIQVYGSSHSSEYNASKSEAPQPESVYIEDIFSFRRSQSLYGSFKGGL 2922
            HIKV APQK+TLS++VYG  H+SEY   + EA QP  V I+DIF FR+SQ LYGSFKGGL
Sbjct: 901  HIKVGAPQKKTLSVRVYGCLHTSEYAEEQKEANQPIQVKIDDIFKFRKSQPLYGSFKGGL 960

Query: 2923 GHMKL 2937
            GH+KL
Sbjct: 961  GHVKL 965


>ref|XP_002308028.1| predicted protein [Populus trichocarpa] gi|222854004|gb|EEE91551.1|
            predicted protein [Populus trichocarpa]
          Length = 949

 Score = 1439 bits (3725), Expect = 0.0
 Identities = 691/959 (72%), Positives = 804/959 (83%)
 Frame = +1

Query: 61   EIIKPRTDKRDYRRIXXXXXXXXXXXXDPETDKAAASMNVGVGSFCDPAGLEGLAHFLEH 240
            EI+K RTDKR+Y+RI             P   + AASMNV VG F DP GLEGLAHFLEH
Sbjct: 2    EIVKARTDKREYKRIVL-----------PNALQCAASMNVSVGCFSDPDGLEGLAHFLEH 50

Query: 241  MLFYASEKYPLENSYSKYITEHGGSTNAYTSSEHTNYYFDVNTNCFEEALDRFAQFFLKP 420
            MLFYASEKYPLE+SYSKYI EHGGSTNAYT+S+HTNY+FDVN++CFE+ALDRFAQFF+KP
Sbjct: 51   MLFYASEKYPLEDSYSKYIIEHGGSTNAYTTSDHTNYHFDVNSDCFEDALDRFAQFFIKP 110

Query: 421  LMSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSDKAHPYHKFSTGSWDTLEVRPKE 600
            LMS+DAT REIKAVDSENQKNLLSDGWR++QLQKHLS++ HPYHKFSTG+WDTLEV+PKE
Sbjct: 111  LMSADATVREIKAVDSENQKNLLSDGWRINQLQKHLSEEGHPYHKFSTGNWDTLEVQPKE 170

Query: 601  RGLDTRQKLIEFYENNYSANLMYLVVYGNKTLDEMQNLVCHEFGEVRNTDRSCFQFPGQP 780
            +GLDTR +LI+ YE NYSANLM LV+Y  ++LD++Q+LV  +F E+RN DRSCF FPGQP
Sbjct: 171  KGLDTRLELIKLYEENYSANLMNLVIYAKESLDKIQSLVEEKFQEIRNNDRSCFSFPGQP 230

Query: 781  CLPEHLQILVKTVPVKQGHRLRVIWPITPSIRHYKKAPCRYLGHLIGHEGEGSLFYIFKQ 960
            C  EHLQILV+TVP+KQGH+LR++WPITP I HYK+ PCRYLGHLIGHEGEGSLFY+ K 
Sbjct: 231  CSSEHLQILVRTVPIKQGHKLRIVWPITPGILHYKEGPCRYLGHLIGHEGEGSLFYVLKT 290

Query: 961  LGWATSLSAGEGDWTSEFSFFKVSIDLTDAGHDHIEDIVGLLFKYVLLLQKSGVKKWIFD 1140
            LGWAT LSAGE D T+EF+FF   I+LTDAGH+H++D+VGLLFKY+ LLQ+SGV KWIFD
Sbjct: 291  LGWATDLSAGEVDGTTEFAFFTAVINLTDAGHEHMQDVVGLLFKYIHLLQQSGVCKWIFD 350

Query: 1141 ELAAICETVFHYQDKVPPIDYAVHISSNMQIYPPKDWLVASSLPSEFSPDTIQMILDELS 1320
            ELAAICET FHYQDK PPI Y V I+SNMQ+YP KDWLV SSLPS FSP  IQ +L++LS
Sbjct: 351  ELAAICETSFHYQDKTPPISYVVRIASNMQLYPQKDWLVGSSLPSNFSPSIIQTVLNQLS 410

Query: 1321 LNNVRIFWESQKFKGHTDMVEPWYGTEYSVQKISSSMIQQWIEKAPDEHLHLPTPNVFIP 1500
             +NVRIFWES+KF+G T M EPWY T YSV+KI+ SMIQ+W+  AP+E LHLP PNVFIP
Sbjct: 411  PDNVRIFWESKKFEGQTAMTEPWYKTAYSVEKITGSMIQEWMLFAPNEDLHLPAPNVFIP 470

Query: 1501 TDLSLKEMQDKAKFPVLLRKSSYSRLWYKPNTMFCTPKAYVRIDFHCPYTSHSPEAVVLT 1680
            TDLSLK+ Q+K KFPVLLRKSS S LWYKP+TMF TPKAYV+IDF+CP+ S SPE  VLT
Sbjct: 471  TDLSLKDAQEKVKFPVLLRKSSSSSLWYKPDTMFSTPKAYVKIDFNCPFASSSPETEVLT 530

Query: 1681 DIFTRLLMDYLNEYAYDAQVAGLYYAINHADTGFQVIVVGYNHKMRILVDTVLEKIAEFK 1860
            DIF RLLMD LN+YAY AQVAGLYY I++ D+GFQV VVGYNHK+RIL++TV+EKI+ FK
Sbjct: 531  DIFARLLMDDLNDYAYYAQVAGLYYGISNTDSGFQVTVVGYNHKLRILLETVIEKISNFK 590

Query: 1861 VKRDRFYVIKETVTKQYQNLKFQQPYQQAMYYCSLILEDHSWPWTXXXXXXXXXXXXXXX 2040
            VK DRF VIKE VTK+Y NLKFQQPYQQAMYYCSL+L+D +WPW                
Sbjct: 591  VKPDRFSVIKEMVTKEYGNLKFQQPYQQAMYYCSLLLQDQTWPWMEQLEILPHLQAEDLA 650

Query: 2041 KFSPLLLSKAFLDCYVAGNMEPKEAESMIFHIEDIFFNGPKHICRALLPSEHLTNRIVKL 2220
            KF PL+LS+AFL+CY+AGN+E  EAESMI HIED+F  GP  IC+ L PS+HLT+R++KL
Sbjct: 651  KFIPLMLSRAFLECYIAGNIERSEAESMILHIEDVFNEGPDPICQPLFPSQHLTSRVIKL 710

Query: 2221 EKGTCYFYKCEVLNKDDENSALVHYIQVHQDDFMMNVKVQLFALIAKQAAFHQLRSVEQL 2400
            E+G  Y Y  E LN DDENSALVHYIQ+H+DDF  NVK+QL ALIAKQ AFHQLRSVEQL
Sbjct: 711  ERGINYLYPIEGLNPDDENSALVHYIQIHRDDFTWNVKLQLLALIAKQPAFHQLRSVEQL 770

Query: 2401 GYITVLMQRNDSGIRGLQFIIQSTVKDPGQINTRVEAFLKEFESIFYALSDDEFRSNVDA 2580
            GYITVLMQRNDSGIRGLQFIIQSTVK PGQI+ RVEAFLK FE+  Y +++DEF+SNV+A
Sbjct: 771  GYITVLMQRNDSGIRGLQFIIQSTVKGPGQIDLRVEAFLKMFETKLYGMTNDEFKSNVNA 830

Query: 2581 LIDMKLEKHKNLREESAFYWREIADGTLKFDRRDAEVVALKSLKKEDLTNFFDEHIKVSA 2760
            LIDMKLEKHKNLREESAF+WREI+DGTLKFDRR+ EV ALK L ++DL +FFDEH+KV A
Sbjct: 831  LIDMKLEKHKNLREESAFFWREISDGTLKFDRRECEVAALKQLTQQDLIDFFDEHVKVGA 890

Query: 2761 PQKRTLSIQVYGSSHSSEYNASKSEAPQPESVYIEDIFSFRRSQSLYGSFKGGLGHMKL 2937
            P+KRTLS++VYG  HS EY + KS+   P +V IEDIFSFRRSQ LYGSFKGG GHMKL
Sbjct: 891  PRKRTLSVRVYGKLHSCEYPSDKSQQLPPNAVQIEDIFSFRRSQPLYGSFKGGFGHMKL 949


>ref|NP_001233926.1| insulin degrading enzyme [Solanum lycopersicum]
            gi|15485612|emb|CAC67408.1| insulin degrading enzyme
            [Solanum lycopersicum]
          Length = 971

 Score = 1420 bits (3675), Expect = 0.0
 Identities = 675/971 (69%), Positives = 805/971 (82%), Gaps = 4/971 (0%)
 Frame = +1

Query: 37   MAVGKSE----TEIIKPRTDKRDYRRIXXXXXXXXXXXXDPETDKAAASMNVGVGSFCDP 204
            MAVGK E     EI+KPR DKRDYRRI            DPETDK AASMNV VG+F DP
Sbjct: 1    MAVGKKEENMAVEIVKPRIDKRDYRRIVLQNNLEILLISDPETDKCAASMNVCVGAFSDP 60

Query: 205  AGLEGLAHFLEHMLFYASEKYPLENSYSKYITEHGGSTNAYTSSEHTNYYFDVNTNCFEE 384
             GLEGLAHFLEHMLFYASEKYP+E+SYSKYITE+GGSTNA+TSSE TNYYF+VN + FEE
Sbjct: 61   EGLEGLAHFLEHMLFYASEKYPVEDSYSKYITENGGSTNAFTSSEDTNYYFEVNADGFEE 120

Query: 385  ALDRFAQFFLKPLMSSDATTREIKAVDSENQKNLLSDGWRMSQLQKHLSDKAHPYHKFST 564
            ALDRFAQFF+KPLMS+DATTREIKAVDSE+QKNLLSD WRM+QLQKHLS + HPYHKFST
Sbjct: 121  ALDRFAQFFIKPLMSADATTREIKAVDSEHQKNLLSDPWRMNQLQKHLSAENHPYHKFST 180

Query: 565  GSWDTLEVRPKERGLDTRQKLIEFYENNYSANLMYLVVYGNKTLDEMQNLVCHEFGEVRN 744
            GSWDTLEVRPKERG+DTRQ+L++FY  NYSANLM+LVVY   +LD+++ LV  +F ++RN
Sbjct: 181  GSWDTLEVRPKERGIDTRQELLKFYSENYSANLMHLVVYSKDSLDKVEQLVRGKFQDIRN 240

Query: 745  TDRSCFQFPGQPCLPEHLQILVKTVPVKQGHRLRVIWPITPSIRHYKKAPCRYLGHLIGH 924
             DR+   F GQPC+ EHLQILV+ VP+KQGH+L++IWPITP I HYK+ PCRYLGHLIGH
Sbjct: 241  IDRNQIHFTGQPCIMEHLQILVRAVPIKQGHKLKIIWPITPGIHHYKEGPCRYLGHLIGH 300

Query: 925  EGEGSLFYIFKQLGWATSLSAGEGDWTSEFSFFKVSIDLTDAGHDHIEDIVGLLFKYVLL 1104
            EGEGSLFY+ K+LGWATSLSAGE DWT+EFSFFKV+IDLTDAG DH EDI+GLLFKY+ L
Sbjct: 301  EGEGSLFYVLKKLGWATSLSAGESDWTNEFSFFKVAIDLTDAGQDHFEDIMGLLFKYIHL 360

Query: 1105 LQKSGVKKWIFDELAAICETVFHYQDKVPPIDYAVHISSNMQIYPPKDWLVASSLPSEFS 1284
            LQ++G  KWIF+EL+AICET FHYQDK+ P DY V+++ NMQ YPP+DWLVASSLPS+F+
Sbjct: 361  LQQAGASKWIFEELSAICETAFHYQDKIRPSDYVVNVAMNMQHYPPEDWLVASSLPSKFN 420

Query: 1285 PDTIQMILDELSLNNVRIFWESQKFKGHTDMVEPWYGTEYSVQKISSSMIQQWIEKAPDE 1464
            P  IQ  L+EL+ +NVRIFWES KF+G+T M EPWYGT YS++K+    I+QW+E AP E
Sbjct: 421  PSIIQSFLNELNPDNVRIFWESTKFEGNTSMTEPWYGTAYSIEKVGGDSIKQWMEHAPSE 480

Query: 1465 HLHLPTPNVFIPTDLSLKEMQDKAKFPVLLRKSSYSRLWYKPNTMFCTPKAYVRIDFHCP 1644
             LHLP PNVFIPTDLSLK + +K K P+LLRKS YSRLWYKP+T F +PKAYV IDF CP
Sbjct: 481  ELHLPAPNVFIPTDLSLKPVFEKTKVPILLRKSPYSRLWYKPDTAFSSPKAYVMIDFSCP 540

Query: 1645 YTSHSPEAVVLTDIFTRLLMDYLNEYAYDAQVAGLYYAINHADTGFQVIVVGYNHKMRIL 1824
            Y  HSPEA VLT+IFTRLLMDYLNEYAY+AQVAGLYY I+  ++GFQ+ + GYN K+R+L
Sbjct: 541  YCGHSPEAEVLTEIFTRLLMDYLNEYAYNAQVAGLYYDISKTNSGFQLTLFGYNDKLRVL 600

Query: 1825 VDTVLEKIAEFKVKRDRFYVIKETVTKQYQNLKFQQPYQQAMYYCSLILEDHSWPWTXXX 2004
            ++ V+EK+A+F+VK DRF V+KE VTKQYQN KFQQPYQQ MYYCSL+L+D+ WPW    
Sbjct: 601  LEAVIEKVAKFEVKPDRFSVVKELVTKQYQNFKFQQPYQQVMYYCSLLLKDNIWPWNEEL 660

Query: 2005 XXXXXXXXXXXXKFSPLLLSKAFLDCYVAGNMEPKEAESMIFHIEDIFFNGPKHICRALL 2184
                        KF PLL++++F++CYVAGN+E  EAESMI  IED+FF GP+ I + L 
Sbjct: 661  DVLPHLKVDDLVKFYPLLMARSFMECYVAGNVEQAEAESMIQLIEDVFFKGPQSISKPLF 720

Query: 2185 PSEHLTNRIVKLEKGTCYFYKCEVLNKDDENSALVHYIQVHQDDFMMNVKVQLFALIAKQ 2364
             S+HLTNR+V LE+G  Y Y  E LN  DENSALVHYIQVHQDDFM+NVK+QLFALIAKQ
Sbjct: 721  ASQHLTNRVVNLERGVNYVYAAEGLNPSDENSALVHYIQVHQDDFMLNVKLQLFALIAKQ 780

Query: 2365 AAFHQLRSVEQLGYITVLMQRNDSGIRGLQFIIQSTVKDPGQINTRVEAFLKEFESIFYA 2544
             AFHQLRSVEQLGYITVLMQR+DSG+ G+QFI+QST KDP  I+TRVE F+K FES  Y 
Sbjct: 781  PAFHQLRSVEQLGYITVLMQRSDSGVHGVQFIVQSTAKDPKYIDTRVELFMKMFESKLYE 840

Query: 2545 LSDDEFRSNVDALIDMKLEKHKNLREESAFYWREIADGTLKFDRRDAEVVALKSLKKEDL 2724
            ++ DEF++NV+ALIDMKLEKHKNLREES FYWREI+DGTLKFDRRD E+VALK L +++L
Sbjct: 841  MTSDEFKNNVNALIDMKLEKHKNLREESRFYWREISDGTLKFDRRDREIVALKQLTQKEL 900

Query: 2725 TNFFDEHIKVSAPQKRTLSIQVYGSSHSSEYNASKSEAPQPESVYIEDIFSFRRSQSLYG 2904
            T+FFDE+IKV  P+K+ LS++VYGSSHSS++ A K+E  +P +V IE+IFSFRRS+ LY 
Sbjct: 901  TDFFDEYIKVGVPRKKALSVRVYGSSHSSQFQAHKNEQMEPNAVQIEEIFSFRRSRPLYS 960

Query: 2905 SFKGGLGHMKL 2937
            SFKGG GH++L
Sbjct: 961  SFKGGFGHVRL 971